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<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC4</accession>
    <name>A9AUC4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0392"/>
    <dbReference type="EnsemblBacteria" id="ABX03043">
        <property type="protein sequence ID" value="ABX03043"/>
        <property type="gene ID" value="Haur_0392"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0392"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_4_0"/>
    <dbReference type="OMA" id="YWAMMHK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-395-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30753" checksum="091AC37B4DC1C782" modified="2008-01-15" version="1">MSVIVIDDQVVHYETFGRGRPVLFLHGWLGSWRYWMPTMEFVSKDFRTYSFDFWGFGDSDKTSTAKSISITNFSDQVIRFLDAMGIDKVPLVGHSMGGMVALKTAIRHPNRISRVAAIGAPIVGTSLSGLLKLTDNQYVSRAMARVPVVTKFLFRWFLGNVNDTAYGEILDDSVKPTEESLRRAVGSMMRTDLRPELEQLTIPTLIIHGARDDIVNPNQADIFLQRDMANTQVFVMPESRHFPFLDEPAQFNKVLHAFLKRPVNEARAAAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM7</accession>
    <name>A9AUM7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1911"/>
    <dbReference type="EnsemblBacteria" id="ABX04554">
        <property type="protein sequence ID" value="ABX04554"/>
        <property type="gene ID" value="Haur_1911"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1911"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107126_0_0_0"/>
    <dbReference type="OMA" id="PRWDLER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1940-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="20827" checksum="662EC63B6CD3314F" modified="2008-01-15" version="1">MELPLMVNVQQLKQQLQAGNDLVLLDVRTAAEFESVHIDGSLNVVLDQIEQQRQQLSESLKHPVVLVCRSGNRARQAAALLQHVNLPNLHILEGGIQAWQAANEPVKQGRQRWALDRQVRGLAGSIVLASMLGSLLWPPLRWVAAFMGAGLTYSALTDSCAMGMLLSKLPYNRQTTCQPSFTPIQNEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN2</accession>
    <name>A9AUN2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1916"/>
    <dbReference type="EnsemblBacteria" id="ABX04559">
        <property type="protein sequence ID" value="ABX04559"/>
        <property type="gene ID" value="Haur_1916"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1916"/>
    <dbReference type="eggNOG" id="COG1337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085066_0_0_0"/>
    <dbReference type="OMA" id="LMEIDEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1945-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="25526" checksum="088E92168FC1F764" modified="2008-01-15" version="1">MSSYTIKITLLSDTTFGTGDGIVGLIDQEVEYDQYGFPFLRGRTLKGLLCDECDTFIAGIESNSNPEFDEIRRMRDQLFGVGGSVARKESRLHFSDAILPLAIQNTLKSYELPTHEILNALTVIRRQTAIENATGVAKPHSLRSQRAVIHGLTFESIIDCKQDLEPAAKELLDLSCRLLRRLGTQRNRGRGRVKCCLIDHSSANQHDRDEHNKPNNFSTLKQLLGVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU4</accession>
    <name>A9AUU4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3898"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06532">
        <property type="protein sequence ID" value="ABX06532"/>
        <property type="gene ID" value="Haur_3898"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3898"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_0"/>
    <dbReference type="OMA" id="VFPLHGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3940-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="28"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="236"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="433" mass="48244" checksum="8770DB5DFE6E50F3" modified="2008-01-15" version="1">MAITPVASIDHQLRVAMLCRAVFPLHGFGGIERHVFHLVTHLSDLGVKLDLWTQTIPHDVPTAGEAYARLCQNPLIELHETRYDRTSPWLRPNSIIGRQFNYPIFTWQQASAVAKTAQQGQIDIVHTQGLCALGWGLVRQQQPSLRRIPQLANPHGMEEYKNVDWRKQLAYAPFRAQYSWSHRQADCAIATDACTADDLPNLLGVDPTRVAVLPSAIDVAEALGQVDEQLGNELVQRLQLADHDLVFLTVSRLERNKGYHLLLAALAELRDLLPASWRLLMVGTGKEQAALEQQAQSLGLAQHVSLLGRLSDRELHSLYEHVDLFIHPTLYEGSSLVTLEAMIHRLPVVATAAGGIPDKVISGHNGLLVPANNQRALVNALRLALDLREYWPQWGAAGAAIVRRSFDWPVVARQTLATYRELLQSRSLRGGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY7</accession>
    <name>A9AUY7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3941"/>
    <dbReference type="EnsemblBacteria" id="ABX06575">
        <property type="protein sequence ID" value="ABX06575"/>
        <property type="gene ID" value="Haur_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3941"/>
    <dbReference type="eggNOG" id="ENOG502ZIW0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_335508_0_0_0"/>
    <dbReference type="OMA" id="ANVCHAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3983-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="781" mass="84233" checksum="251454C0C1C0B9D1" modified="2008-01-15" version="1">MVRNRKRRRVLSSFLITLTLLVTFISSVSAISLNATVSLSSGDFASGYFGLTGLTQQDQVIGDVTYGGVQLIPQGALAQWSDASNQLCRTLADMGTVSFKQHLYAIGGSTASSGNVAVVSEVCRATVTDTGGETTEWTELPQTLPVPLTRMSTVVVTNTSDPTKGIMYTFGGQSASTGDIEYTDKIYSNVINADGSLNTWQTQALTTGEKLINTTATAYTTPNGQTYIYLIGGKTRDTSALFSPIYVRRSVRRTLVGPNGVLGPWQSMPDLPITPDMFTPTNGCDENVGLHSMDVANFDAITLTSTYRAFLVVGGTFELGTGHVAVGCTRTVEGSAQAMLGKLDTNGMLTWETQRYILPEPLSSPRVIGVNQKIYVVGGRQGSAGDPTHRIYTSYINIDNFTLPVFGQSNFRVSENALLTSQARSGHGLELIYINFRPVAYMYGGIRVGNTYQQDVLFGFVGTDADIDLTVGGYPSPGVYRSSPLQLRAPAIIEQMLWDATLPNPPINTDIQMQYKLAATRGALETAQWQTVDASPGNDNYSVQGPNVANGTPAVQGQWFQYQALMTTQSPTEVGATPILRNVRIKYKVDGHPSLYVDSATMSTVSTTGITAFTATFKNGIKPGSNDTENVLDADIESQGTFFVDMYLLPPGSADVPPARDPDSGAYPLGMVFTEINRLNLPQDGEFTLDAISDNTIWRRTCPAATVDCPLVVWQALFNKTGTWKVYLVIDSGNYVTEAETPAGQRELDNVYSFNVNSTVVGSTIHMPVVGINFLATPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV32</accession>
    <name>A9AV32_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0459"/>
    <dbReference type="EnsemblBacteria" id="ABX03110">
        <property type="protein sequence ID" value="ABX03110"/>
        <property type="gene ID" value="Haur_0459"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0459"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_0"/>
    <dbReference type="OMA" id="YNRYDAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-465-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="36712" checksum="71ED103F38CE611D" modified="2008-01-15" version="1">MASLTIEQIAELAHVSIATVSRVLNNQPHVRAEVRERVLAVMQEHHYTPHAAARTLAGQRPKVIAVFISRTTATIFRNPTFSHLLQGMTEACNAKGYVLMVSLDSANRADDPATKLLNGRSVDGRIVIPNTINDPLLPQLIADRVPMVLVGKHPLLHHIVSVDIDHFAGSYQAVHHLLKLGHQSVGMIVGSLHALATHDQIEGYQQAYREAGLPIHPALIATGNETEQGGQAAIEQLLALQPRPSALFVSSAVMATGVLQTLHTQGLRVPDDITVVCFDDVPTAASLNPSMTSLHQPMYDLGATAANVLIELIEGKTPSSENTILPISMIVRHENEVWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV80</accession>
    <name>A9AV80_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0509"/>
    <dbReference type="EnsemblBacteria" id="ABX03158">
        <property type="protein sequence ID" value="ABX03158"/>
        <property type="gene ID" value="Haur_0509"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0509"/>
    <dbReference type="HOGENOM" id="CLU_2246248_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-514-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="12621" checksum="625EAAAB7863B93D" modified="2008-01-15" version="1">MAQPDYHVPNNPKKPKFEWRFSVILNILNTSFSIMLVVLIFGGACGVDREAICRGISWMALSGSSWLAALLLLYSLMNFTRTLAFMRWFTIGLPLIPILFVAFVYLRALFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB5</accession>
    <name>A9AVB5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0545"/>
    <dbReference type="EnsemblBacteria" id="ABX03193">
        <property type="protein sequence ID" value="ABX03193"/>
        <property type="gene ID" value="Haur_0545"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0545"/>
    <dbReference type="eggNOG" id="COG1479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011736_6_1_0"/>
    <dbReference type="OMA" id="GAHRIFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-554-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="14"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="420"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="568" mass="66188" checksum="34CB08F1D9D7FEE4" modified="2008-01-15" version="1">MGNTYIESETAPIGDFINKVEALKVPVFQRSFAWTEDEIKLLWDDITAIIELPQPEYFLGSMVFKKKDGYYEIIDGQQRITAIYIILSCIRNIYRINSDTQRNEWFNREYFGKIDINTLTINSKFQMNEINNPFFQKYIVSESNIEEIEENIKNLPKKDTNHLLGKAIKQIYSLLIERQKEFSGTEFSSDALLSIHNIIQKHIYVLILKVSDEADAYTIFETLNDRGLGLTTMELLKNHIFEKSGMYLPSVQNEWSILRDNLLHSDPSDRFIHHYWTSIHGRTSKPQLFRLMRKQVNTPIQAVEFARSLRTSARLYAAFGNPNDDYWNDHEKQTRDNLEVLDILDAQQVMPVLLAAVQKFNPTEFRKLTYALVVMAVRYNLIGELRTGVISNYYSDIPKKIHSGELNKSIKVCREFRSIYPTDEEFEEAFSTKVLSDAKKSRYLLIELEKNFNGGSSQVSNDPRKVNLEHILPQNPSNEWIDTITQAGDDLRKYIYKLGNQALVSTTPNKKSGAKGFIYKNTNLYSKETQIYYTHMLTQYSTWLPADIIRRQKELAKQAVKTWRIEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE4</accession>
    <name>A9AVE4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1992"/>
    <dbReference type="EnsemblBacteria" id="ABX04635">
        <property type="protein sequence ID" value="ABX04635"/>
        <property type="gene ID" value="Haur_1992"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1992"/>
    <dbReference type="eggNOG" id="ENOG502Z7M5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_251160_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2021-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1453" mass="156827" checksum="6EDE959F09B8FFBC" modified="2008-01-15" version="1">MDFAQLEAMLQASLSNQVFKFALNQLNDLILTKLADDYLPNGELHLEHVPEIGKDAAAQRYTIVGQGLSTPFKGLTTTCTFQLVAGVWHVQLAAEAALPNPIGLAFAEVNGSWLAELPFQARPQWRLVSHPTPALTLTGVADFTHLAGGIANLLGQPTHELTGAFELAKHGANLQSIELDAPVLGPTDLGLFQVNQVVLGVKSELVPSLKPPSQLIPALVLATSIPFHAQQQTYNLGLAVYARNLAQNLHFRLDLNQVLQAGFDELASLVHGYSLGQLIPQGLHVEDYFTLSDFFFDFDYQNPHKISLIGLDVRSTTTWDILTFPAGSKASIGNILLAFRLSEPLSSEIKPFLAVSGEVVLDTAILDISTNLPDWEFQAHLREGTTLHVAKLLEMTLGHSAHLPELNIYDLYFGVSSEGFTFHAGISDLWELVPGKLRLTDLAVGLNYATADGVYLGIEVGFDLLEITVTLTGEYQSSQAGWALTGSTGYEQPIPIGQLIDDLASKFGAITLPTPLTGLIIKNIHAGLNTGSFDTTFDCEIDFPVSASQHVALLLKLAIIHESNGIKADFSGHMTLGSLIFDLRFHHDPSHNAFIASYSHSAEQAAIHLRELLGYVWADVPSAIPDIQIDLKDVVFLFDNTGNVKVFVFGFDLGARISLADLPLIGSKFPPDWTVGLENLQVLVVSGEIPKTTIVSLNALLPETVTGLPDQDLTKGLNITAKLQLGSSRQALNLPIAGQDQTAPTKPTTPTQAGSSSTDTAQWFNIQKSLGPVHFERIGVQYSDSVLWFLIDASLSAAGLTLSMQGLGVGSRIDKFELHFTLRGIGIDFKRPPLEIGGALLRVPSADGDDYLGMAIIRASSFGLAAMGGYSTYKGWPSLFVYAALNTPIGGPPYFFVMGLAAGFGFNRALNIPPVGDLLKFPFVSEALGIRPNGTTITDELLALHQYVPPTTGQLFFAAGLHFTTFKVLDAFALLTISVGSSQLEVNLLGLATVAAPPTQGMKDVDPLASLQLALKATLDLLHGYVELSGQLTSESFILDRNCRITGGFAIAAWFGAEHTGDFVITLGGYHPQFNVPSHYPKVPRLGLNWQLADTLSLKGGLYFAMNGSAMMAGGELQLTWESGDLKAWLKAGIDFLIAWKPFHYDVHLYVDIGVSYTLHFLGTHRLSVDIGADLHIWGPEFSGIAKLDLKIFSFEIKFGAAAPALPKPINWIEFQASFLPASQQILSLTVERGLSVSNQAQAEQQPWLINPKELSLNLASAVPISTLMLGSNSINLATSNTQLGVAPLNLPLGHLNSVCTISIRLHDQPAEQHFQLELLHKNAPAALWGDNFIPQPNSPSLVDNTLSGVRIVPIATHSEGETAGIDPQTLLFVPEAKPETFAWKAAVNYTASAETPTERELMMRSNLASAEVQTARSQLLQALGQTAICRINHEYLDGLADVPQLGSWTIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE5</accession>
    <name>A9AVE5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1993"/>
    <dbReference type="EnsemblBacteria" id="ABX04636">
        <property type="protein sequence ID" value="ABX04636"/>
        <property type="gene ID" value="Haur_1993"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1993"/>
    <dbReference type="eggNOG" id="ENOG502Z976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016041_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2022-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="609" mass="67464" checksum="16B413484D9D879F" modified="2008-01-15" version="1">MSNDLIFAEHHLPALPLGKYSLTVTQTLSSTGQLPAGAEPIRQTDYRTTGEMLISGERWSLPETLIGAVFPPVGSTGDHSTTLPHIMLTRSTLPWERTAQASGQLPWLALLVFNEDEKPTPKVLKRADLADPTVLYQLPTSESNETAADLVTVIDLPWATLQPLLPTLADLPLLTHVRRVDVNEQAVVWANRIPQADRMSTVHLVSLEQRYDQTGFMAAGASAETMVRLVSLYSWQFACVAEGQRIEELLTHLDVATIGLPSINNPHADAFLAQGAVLLPHHLRNGEQTVAWYHGPLRASLQVAAANYPHAVSADSLLRFDQRVGVFDVSYAAAWELGRLLGLQNQQFSQALYAWKSQQASQSVSRLQARNTRYDHLPSFGRQVRARSLSEPIPPAIMNFVRRLSLLEGVPFSSLFPDERLLPLESIRFFSLDRAWLAALIDGALSIGRANIDHGNDGYLRLQIVQQLNLPTSISGFAIRSSVIAGWSALEIEAKSSAGSRLEHLNEDTIRLGENMLLLLFADELASLSIHQHAQTIHFGLDRDSNGWHKTLRNGSEIRPLAWHDQQRQILDVAQLASQMSQTLNQPVHSGSFALQMIEGVARVTFERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVG0</accession>
    <name>A9AVG0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2008"/>
    <dbReference type="EnsemblBacteria" id="ABX04651">
        <property type="protein sequence ID" value="ABX04651"/>
        <property type="gene ID" value="Haur_2008"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2008"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_223983_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2037-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="597"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2110"/>
            <end position="2184"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="3177"/>
            <end position="3252"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="634"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="2144"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="3212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="4101" mass="443057" checksum="8ABBADFE3B010F24" modified="2008-01-15" version="1">[encoded data, 4101 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVG4</accession>
    <name>A9AVG4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2012"/>
    <dbReference type="EnsemblBacteria" id="ABX04655">
        <property type="protein sequence ID" value="ABX04655"/>
        <property type="gene ID" value="Haur_2012"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2012"/>
    <dbReference type="eggNOG" id="COG0684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2493647_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2041-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="86" mass="9681" checksum="717D6E481633A908" modified="2008-01-15" version="1">MLQVADLLPALPSLTQLQAAYYTQADALSRSQVMDLVWQEMPRVAGPAFTVQWMPSDNCMLHAAIYRAEPGSIKEHHQWSINALQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK1</accession>
    <name>A9AVK1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04692">
        <property type="protein sequence ID" value="ABX04692"/>
        <property type="gene ID" value="Haur_2049"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2049"/>
    <dbReference type="HOGENOM" id="CLU_2935231_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2078-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="60" mass="6774" checksum="D32F830A263B09BD" modified="2008-01-15" version="1">MVILTIPHVGLRRTRFIGLEKTHLQHVLSAVALNVIRIGAWLDQPRQTPPRRSALSRLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVP4</accession>
    <name>A9AVP4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4012"/>
    <dbReference type="EnsemblBacteria" id="ABX06644">
        <property type="protein sequence ID" value="ABX06644"/>
        <property type="gene ID" value="Haur_4012"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4012"/>
    <dbReference type="eggNOG" id="COG2129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095253_0_0_0"/>
    <dbReference type="OMA" id="DPCHRGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4054-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="30"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="24302" checksum="4628B6CC008B165B" modified="2008-01-15" version="1">MRLLSVSDEVVSMLQTSALRQRVGSIDAIVGCGDLPPSYLEYLVSMLNVPCFYVNGNHDAPEQHEDGRVSVKPQGCDNLDLRVEAVGGLLIAGAGGVLRYRPGEHQYSEAEWAWRMTMLSARVFFAQMRYRQRLDVLITHTPPAGLHDGIGAHRGPQALRRFIDRIAPRYVIHGHVHLNYGYGDQRPLQYGDTLIVNTHGYRLLDLEPMPALSKAQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ2</accession>
    <name>A9AVZ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0582"/>
    <dbReference type="EnsemblBacteria" id="ABX03230">
        <property type="protein sequence ID" value="ABX03230"/>
        <property type="gene ID" value="Haur_0582"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0582"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_2_0"/>
    <dbReference type="OMA" id="FHVRDPF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-591-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="31278" checksum="8C500586E3803C37" modified="2008-01-15" version="1">MQIEVQIVNAFIDGDAGGNPAGVVLQADGLSAAQKLAVAQQVGLSETAFVSKSDVATIKLEFFTPTRQIAHCGHATIATFSLLRQLNRVPTGQLAKETIDGLREIIVADDQAFMQQLAPRYQAFALTDPIAQQALRSLNIPSGDLLRGTVPTLVNTGNSFLIIGLASEQTLAELQPDFGQIQQISEQLDLIGYYLFTPATKQAGRSAGTRMFAPRYGIREEAGTGMAAGPLACYLYDQLGLQQTSFLIEQGWLMQPSSPSVIEVQLSLVDGAIQSLLAGGRAKVMQTLQVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWB2</accession>
    <name>A9AWB2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase internal region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2122"/>
    <dbReference type="EnsemblBacteria" id="ABX04762">
        <property type="protein sequence ID" value="ABX04762"/>
        <property type="gene ID" value="Haur_2122"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2122"/>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020473_5_0_0"/>
    <dbReference type="OMA" id="WDIVAGN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2150-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="232"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="516" mass="58347" checksum="5BDA654693ADC355" modified="2008-01-15" version="1">MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYKTQYDVLIQNITTANSINGYIKPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDNSSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAENLVLMEEIRSITQLIEGNVQAYALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVTTTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQINPHFLYNTLDAIIWMAEAKRTAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLAIQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYHGIKNKRSGGTIVVRGRWLDGDRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSDYGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF7</accession>
    <name>A9AWF7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted protein containing thrombospondin 3 repeats</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4084"/>
    <dbReference type="EnsemblBacteria" id="ABX06716">
        <property type="protein sequence ID" value="ABX06716"/>
        <property type="gene ID" value="Haur_4084"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4084"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591567_0_0_0"/>
    <dbReference type="OMA" id="QQEWTAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4128-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731678" evidence="2">
        <location>
            <begin position="25"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="462" mass="49625" checksum="53EB1DD96271E551" modified="2008-01-15" version="1">MLRVKILLLAIIFLPIQSINQVNAQKIAEISRNTTNEQLDSDSDSLTNSWETNHQLNPYSALGDDGAAGDPDHDGLSNANEQIHATNPRNPDSDADGLNDGWEVRYWLNPTSAIGDHGATGDADRDGLTNQEELFSNTYPNNPDTDGDGLRDGWEVDHQFSPINTTGYHGSAGDVDTDNLNNFQEQAADTNPRHPDSDGDGLPDGLEIEHGSNPLDCDLDADADGLENQPELALATNPFNSDSDGDGLPDGWEVAQQLNPLSVAGIHGANGDGDADGLGQLQEYLHQTNPHQADSDDDGLLDGWEVQHHLNPLSSLAADGANADPDSDSLSNLAEQGFATNPRNADSDNDQLPDAWELQQQLDPLLASGEVGTHGDPDADRLTNLAEYRNSTRPLLADSDGDGLDDGWEVQYTLDPLDGFGVNGANGDPDSDGMNNLIELQRQTHPLQATYLVMLPLAQHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN5</accession>
    <name>A9AWN5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="8" type="ordered locus">Haur_4162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4162"/>
    <dbReference type="EnsemblBacteria" id="ABX06794">
        <property type="protein sequence ID" value="ABX06794"/>
        <property type="gene ID" value="Haur_4162"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4162"/>
    <dbReference type="eggNOG" id="COG0552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_3_4_0"/>
    <dbReference type="OMA" id="GISDQFQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
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    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
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    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="7">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="125"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
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        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX06794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="35673" checksum="5663DFBF16FA69FB" modified="2008-01-15" version="1">MFRRLFGGEERSEQEIKQEEKKIEQSVQKTRSGFFGRITAMFRSEDPITNELWDELEELLIAGDVGAENALKIVERVREKCEKKGFKFASEARSLLKSELVNRLDVDTPQYSERSTKPYVILVVGVNGVGKTTLIAKLANRYKAMGKNVILAAADTFRAAAIDQLQHWADRVGVPMISQQPGSDPGAVAYDATQATYNQQADVLIIDTAGRLQSKHNLMKELEKISNVVKKRWQYAPHEVLLVLDATTGQNGLIQARAFTQAAQVTHLALTKLDGTAKGGIAFAIVQEIERPIKYIGTGETINDLALFDGESFVNALFEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX23</accession>
    <name>A9AX23_HERA2</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04831.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX04831">
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        <property type="gene ID" value="Haur_2191"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2191"/>
    <dbReference type="eggNOG" id="COG3266">
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-2219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735069" evidence="2">
        <location>
            <begin position="25"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="26213" checksum="8596ED781C632B85" modified="2008-01-15" version="1">MKRRLLWWAIPLIALMLAVQLAQAQTGGVFSLDWSTIDSGGGNSTGGNFDLHGSIGQADASVAHTGGNFSVEGGFWYGVSTLTPTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTNTPTATATETSTPTNTPTETSTPTATATNTPTETSTPTATATATNTPTNTPTATVTATNTPTETSTPTATATNPIPSYTIYLPQTMRGESSLRSNNPQRSIIQSILQRGFLAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX30</accession>
    <name>A9AX30_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2198"/>
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        <property type="gene ID" value="Haur_2198"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2198"/>
    <dbReference type="HOGENOM" id="CLU_536422_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2226-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="544" mass="60247" checksum="622B8A59EEE9D3C9" modified="2008-01-15" version="1">MKNTDVFNSFDLIVPITQKTINDQLTHLVRLGVINPELIITQVWDDPNKQDVYTILKSSADLPKNSDGSIDSSKLDGYLDGILLPQISIHESGTVVLLLLNFLSGTFGYWGGSPHNPTWMTVDMSNWKFGISVNMDLATLAKNDLDQKIKVPDNVQQQLSGFIDNMFTVNHLFMDFESTDLINFDPTVTSVGNAGDDVKKQFVFFMQEYLKSQKDAGNPYVLGYTMSATDQSNYASYGDVPDSLRPVGTTYNFYNDPTNPDISTLNFALVTKGGHQSISTTPGNFDSNWISPNEQCDAKMIYSHQVLLEEYFLKPIFQQLHDGIYAQIKDHLSVDSGANYDQAKSATANGFSYSIINDKDGDDQYVNNYSVQIVNQAQSAQVDLNFSGHLYFYKEQSKDMFFCTAKGWAWTGLDWSGTVSLITTKDTNGRPNLSITKQFSISNVDKGQDKNSCAEAWTIIGDILGSILDAFSFGLDGNFFANLFANAFGIHIDSIGNIGVVLGDIGTTINTALILPAGNVFFISNPTADPLANFYLELHYKSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX81</accession>
    <name>A9AX81_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4169"/>
    <dbReference type="EnsemblBacteria" id="ABX06801">
        <property type="protein sequence ID" value="ABX06801"/>
        <property type="gene ID" value="Haur_4169"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4169"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_0"/>
    <dbReference type="OMA" id="MWRWQRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4215-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29717" checksum="2C52C93AE099EE2E" modified="2008-01-15" version="1">MASHLVNGVRYYYEERGSGDQVIFFGHGLMYHWRIFEPQMEYFAAKGFRCIAIDWRGQGQTEGGGTLDDYSMYRLGADAYQLLSDLGIKRVHWVGVSMGGMIGLRLYPKHPELFLSFTLIDSSAGDAPELLDGYRQMGDAYLAYGLIPPLQEGLDAVFYTPKMAERHPQVLAYWHAYWTNADRESLYKAIIPVIDRDDVTDTISQIAVPTLIVVGVEDMSTPPAKSEAMQQLIANAQLRYIDDASHMSILEQPEAITAAMAEFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK1</accession>
    <name>A9AXK1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ordered locus">Haur_0767</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0767"/>
    <dbReference type="EnsemblBacteria" id="ABX03415">
        <property type="protein sequence ID" value="ABX03415"/>
        <property type="gene ID" value="Haur_0767"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0767"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_1_0"/>
    <dbReference type="OMA" id="RMASVNG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="58" mass="7000" checksum="6285DB3D5217B4B8" modified="2008-01-15" version="1">MPKRTWQPKRIKRRRVHGFLERMQTRTGRAVLKARRQRGRWKLTVSDKRRPAGPGGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL4</accession>
    <name>A9AXL4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0780"/>
    <dbReference type="ESTHER" id="hera2-a9axl4">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03428">
        <property type="protein sequence ID" value="ABX03428"/>
        <property type="gene ID" value="Haur_0780"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0780"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_3_1_0"/>
    <dbReference type="OMA" id="FWVTPRS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-792-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="30032" checksum="4EADCF7E48FE0D66" modified="2008-01-15" version="1">MPTKTIVLIHGLFVSKHSWQPWVEYYQAKGYTVLTPAWPGRDQSVAELKQRSNDPALAQHTLKESIDYHVKFIQSLPEKPIVIGHSMGGLITQILANRQLISAGVAIDSAPPQGVISTKWSFIKSALPMLNPFRSTSKPFMMPFEHFQYSFVNGMPLAEQQAIYQNQVVPESLHNLRQSLTSVSRVDFKAEHAPLLLIAGEIDHIIPASLNYSNYRKYRNSKSLTDFKQFAGRNHYIVGQPNWQEVAEYALNWVETKALASQSVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ2</accession>
    <name>A9AXQ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0818"/>
    <dbReference type="EnsemblBacteria" id="ABX03466">
        <property type="protein sequence ID" value="ABX03466"/>
        <property type="gene ID" value="Haur_0818"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0818"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="EYMWEFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-832-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
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        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="160"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="160"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29619" checksum="6AD85426AF240D4D" modified="2008-01-15" version="1">MSQASILLVDDEFPIRATLGDLLRRRGYDVQTADSGEEALDRIAQRPFDLFLLDLRLPGVDGITVAQRVRERYPDAAILILTGHGSLDSAIEGIHLGVFDYMLKTSSPQDVLARVKSALEAQADQRHKKSLMNTLQTVVSELGGKQQEPSETPTQQPAGDQWIRVGELEIGLWRQMARLGDQTLNLTPTEFRLLSCLAQQAGLVMSYANLLRCAQGYEAESSEAAELLKPHIYHLRQKIEPDPSNPRYILTVRGTGYVLAVEAPQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY9</accession>
    <name>A9AXY9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2315"/>
    <dbReference type="EnsemblBacteria" id="ABX04955">
        <property type="protein sequence ID" value="ABX04955"/>
        <property type="gene ID" value="Haur_2315"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2315"/>
    <dbReference type="eggNOG" id="ENOG502ZTG0">
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    <dbReference type="HOGENOM" id="CLU_1737672_0_0_0"/>
    <dbReference type="OMA" id="TPWFVDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2343-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039437">
        <property type="entry name" value="Put_lumazine-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12893">
        <property type="entry name" value="Lumazine_bd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="15527" checksum="7B9A5929004DB075" modified="2008-01-15" version="1">MHHSSTNDDIAAIQQAALDYLESQHNLDPAQMQRSIHPRMVKRTFWTHRGTGKQYLREASAEEMILLAASYNRDGDKFPATPRKTVEILDVQASVASVKLTADEWIDYMHLVKINDQWTVINVLWAYHDQDLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYA8</accession>
    <name>A9AYA8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0842"/>
    <dbReference type="EnsemblBacteria" id="ABX03490">
        <property type="protein sequence ID" value="ABX03490"/>
        <property type="gene ID" value="Haur_0842"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0842"/>
    <dbReference type="eggNOG" id="ENOG502ZWP7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2556168_0_0_0"/>
    <dbReference type="OMA" id="RRWVQIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-856-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9213" checksum="704A57780EB57D5A" modified="2008-01-15" version="1">MSELEPAALIIALLASVYGALAHLFWGQRWRHLPLFLGTALIGCLMSYAFNLHFIGAGPVPAGVPLVESTIAAWIMLILATRLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC9</accession>
    <name>A9AYC9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0863"/>
    <dbReference type="EnsemblBacteria" id="ABX03511">
        <property type="protein sequence ID" value="ABX03511"/>
        <property type="gene ID" value="Haur_0863"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0863"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019557_0_0_0"/>
    <dbReference type="OMA" id="DPYGWYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-877-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="262"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="809" mass="88716" checksum="C7B8BE598895F48A" modified="2008-01-15" version="1">MRVLELTMQRSLILGLLIMMLGGATLPFVVHASPQQPQPSQQPTHGLSSLDGGVQGFLQRQNSSLAKLDIDGQPASQIIEGMAAYYNIEARIVLALLETTSQLISNPTLPTTATEQPFLAGPKGFLSQIDWAAKEIRVGLGPYDSALVLNFSDGTQQKLNPNDDPHALTVKRFLAFERDQATWQQLVARYSKVYHDLFQNEPVVAPSTPPVSTGFLSIPWEQGARMVHSSHFDHTYPMVDSGGDGNDVMINYQGKSGLSYNSHDGHDYYFPDLPYGTPIVAAAPGWAYARTTRGLGVLIQHAGEAAGYETVYWHLDDFAPSFKGFIDAAKPRWVERGELLGWSGATGFTTGAPHLHFEVRHNGNQVDPYGWYGPGADPCTNYVKCEASVWLWNDSVPWSRPDGPAPTDTTPPSALLTINPAEDLALVAHFENNPLPAVGPMAASDQLSYSSGKFGQAVKVGDGALTYPASPTLTLNQGTLALWVNVPKTWPSSRTGRHYLLAASQNPVDPDKIYRNTLALRHEQTEQAIWTFWTVDQAGQEHSLSVPDTLNAGWHHFAISWDQTTGNKRLLINGMLVNEASKVSLPSEVGEDLNVGRWTIGAGISNVAIDELLSYKRQLAADEIYRLATSEQALAASSTSTDQHDLLILTPALDNGGGVIKAQLGINGIYAAPMTYYRAYRWTLPNVEGSYTISVRLTDRMGNTTTLSQTISIDHPPQASVNIRDINDLGATLVLSATDANQPLAMALSAYPSPSFKQWEQFSIERQWQWNPITARRVYVWFRDANGNERGPIVAGPDLFRAYLPRIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ7</accession>
    <name>A9AYJ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0931"/>
    <dbReference type="EnsemblBacteria" id="ABX03579">
        <property type="protein sequence ID" value="ABX03579"/>
        <property type="gene ID" value="Haur_0931"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0931"/>
    <dbReference type="eggNOG" id="COG1100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077110_0_0_0"/>
    <dbReference type="OMA" id="MSTINFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-945-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21554" checksum="3BF9DF30D67D1237" modified="2008-01-15" version="1">MAIINVGVREIHCKIVYYGPGMCGKTTNLQYIHSQVPREAKGDLLSIATETERTLFFDFLPLDLGKVRGFSTRFHLYTVPGQILYERTRVAVLNGADGVVFVADSQRDKLQEDIKSLQELARNITRQNKKFSEFPIVLQYNKRDMPGALPTPVMDKYLNPLGWQRYEAVATTGVGVFDTLKAISKLVISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ27</accession>
    <name>A9AZ27_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4435"/>
    <dbReference type="EnsemblBacteria" id="ABX07067">
        <property type="protein sequence ID" value="ABX07067"/>
        <property type="gene ID" value="Haur_4435"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4435"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OMA" id="EPIKVFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4490-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="4"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="35670" checksum="0BC5EA91AFB74861" modified="2008-01-15" version="1">MTYLVTGGAGFIGSHLCETLLQRGERVIAFDNFNDYYSPERKRRNVAGLLDHLNFVLWEGDLRDPASLLALFEQHRPSHVAHLAGMANPRYSLQYPALYSAVNVEGSVNVWQAAIQYGIQAFVQASTSSVYGLAPTPWHEELATDRPLSPYAATKKASELLAYTFHYQTQIPTRVVRFFTVYGPKGRPDMTPTIFVEAMRKQEPIVLYNGGVDVYRDWTYVDDIVSGVIAVLDSDRAFDIFNLGNSTPVMLRSFIDTLQAITGLNAIIEAKPLSSADPPITFADTSKAQQLLGWKPTIDIEDGLERYWHWYKTEYDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B042</accession>
    <name>A9B042_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_1101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1101"/>
    <dbReference type="EnsemblBacteria" id="ABX03749">
        <property type="protein sequence ID" value="ABX03749"/>
        <property type="gene ID" value="Haur_1101"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1101"/>
    <dbReference type="eggNOG" id="COG0460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_0_0_0"/>
    <dbReference type="OMA" id="FNEFSTT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1121-MON"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_aspartokin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="entry name" value="PTHR43070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homoserine_dh" evidence="10">
        <location>
            <begin position="136"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX03749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="35328" checksum="09E0BBEF689BDA2F" modified="2008-01-15" version="1">MHNLAIYGFGGVGRAVLAQALPHFNLALVADRSGYVAGPLSNERWLAVATAKAQGATLASLPEGSSGDWRAALPAGCLVADTTAEANAAQLVELVGRGMRLALANKKPLCEDLNLFQALVAERCTRYEATVGAGLPIVVTTNLLRDTGDQVQRIEGGLSGTLGFLLSSIEQGQPYSAAVREAKALGWTEPDPRDDLGGVDVARKALILARTLGYQWNLSDITIEPLYPAEFADLSIAEFMAQLEQLDPGYAQRQAEAVAQGQTLRYVAAITSEGARVGLQAVAKDSPLGSLKGPDNMVAWTTNRYQERPLVVRGPGAGVEVTASAVLFDLLAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0D2</accession>
    <name>A9B0D2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2603"/>
    <dbReference type="EnsemblBacteria" id="ABX05241">
        <property type="protein sequence ID" value="ABX05241"/>
        <property type="gene ID" value="Haur_2603"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2603"/>
    <dbReference type="eggNOG" id="COG0381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041674_0_1_0"/>
    <dbReference type="OMA" id="KPCITMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2631-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="352" mass="39790" checksum="19B36692DD66AC5C" modified="2008-01-15" version="1">MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFPGNYSIGAAIDWVREQIRRHDIDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKRMYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFNIGNTTVDLIHDFAHELTPRRNDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLLSRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGANVVTGFEPTAIIAAVRNQRAKKGQQFSPVYGERGVGQRIVATLQAHFRSWSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G6</accession>
    <name>A9B0G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent DNA helicase, RecQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4553</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4553"/>
    <dbReference type="EnsemblBacteria" id="ABX07184">
        <property type="protein sequence ID" value="ABX07184"/>
        <property type="gene ID" value="Haur_4553"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4553"/>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_14_3_0"/>
    <dbReference type="OMA" id="GNYKFLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4608-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="48"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="242"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="6">
        <location>
            <begin position="787"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="864" mass="95862" checksum="4F88F4457C3A2C73" modified="2008-01-15" version="1">MTLVDPETPLFTFDEAEAQPTALANELTEALREHFGLPGFRSGQQQVIERVMAGRSTLALMPTGAGKSLCYQLPALLLPHATIVISPLIALMKDQLDGLPEAVRERATFINSAIPFDEVRTRLRGLSEGRYKLVYVAPERLRQRQFLYALQQVGISLFVVDEAHCVSLWGFSFRPDYLFIREALRELGNPLVLGLTATASPATEKAICEQLGDLETVRTNVFRPNLHFELIKASNKEKKQAAILSLCSQIDGAIIVYARSRNSCEELAEQLRKTGVVAEAYHAGCPDRDAIQDRFMRGETRVIVATIAFGMGVDKRDVRAVIHANLPKSLEDYAQEAGRAGRDGQISRCIMLYNFFDKRQLKEWLESSHFGVEELRELYKAVLGQIGKGQGTINQAQLMELSGFDETRLRVGLGILEHVGLVRRHFDLPRVCKLRRGEAPATPEINQLCEWFSLGRWWQDVSSLDLAAALRIAPSQLEPTLLAWQEQGLLGYEGVAREVLLEVLPSPKDTRERMYQVLKQWRSTQERQLDSLTQYVEASHCRHRILAAQFGQRLPACGNACDICQSGRITISRPPNVLQPQTMPLVGSNWGNGGAISDHQRIMVEAVREHPQQLTSRDLAHILAGSRGYSSHPLFGALAERSFDSIRAEIDVLVDAGTLAYQGATLVAVVAAPKRTGNQQRDIALQVLATLTRLPYPLGRTGLVRLLKGVSDAKRSPDHGVLAHATMEQIEVVVEALVEAQLLDRQQQGLYPLLALNSAGRAVLNDPQSLPVLNIQGKRDSAKDEQLQADGELLLLLKSWRSEQARKLNLPHYMIIPDSVLFDLAAYQPTNTQELSTIKGIGSQKLAQWGADLLSLITTGKPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0P2</accession>
    <name>A9B0P2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Histidine ammonia-lyase</fullName>
            <ecNumber evidence="3 6">4.3.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidine = NH4(+) + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:21232"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="EC" id="4.3.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PAL/histidase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.3" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4629"/>
    <dbReference type="EnsemblBacteria" id="ABX07260">
        <property type="protein sequence ID" value="ABX07260"/>
        <property type="gene ID" value="Haur_4629"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4629"/>
    <dbReference type="eggNOG" id="COG2986">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_4_0_0"/>
    <dbReference type="OMA" id="CAPQVAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4686-MON"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005921">
        <property type="entry name" value="HutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01225">
        <property type="entry name" value="hutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="528" mass="56397" checksum="2B6B399395AC8597" modified="2008-01-15" version="1">MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTGFGHFQNRTIDRDHVRELQRNIIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLVAQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLGLGEAVAPGQSPVHGQRMSGAEVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAALPAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVPQVHGAIRDAACYGRWATEIELNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMDFLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGLHSGMMLIQYTAVALASENKVLVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHEHLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0W7</accession>
    <name>A9B0W7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1189"/>
    <dbReference type="EnsemblBacteria" id="ABX03837">
        <property type="protein sequence ID" value="ABX03837"/>
        <property type="gene ID" value="Haur_1189"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1189"/>
    <dbReference type="eggNOG" id="COG2839">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109297_0_1_0"/>
    <dbReference type="OMA" id="KWGQIGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1211-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007403">
        <property type="entry name" value="DUF456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04306">
        <property type="entry name" value="DUF456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="150" mass="16156" checksum="E3465C346F2A1414" modified="2008-01-15" version="1">MFLGLVSVVILPILPGAALIWLGALLYASMTDFVVIGWGTLAVLGAIALIAMTSDIWVGALGQRRGGASIWATIFSMIGGIIGLLILNIPGMLIGSIIGALLPEWQRWRDRKFVLDVSWRTIKNWLVSIAIQVSLGLVMVTIFLVRVITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9B116</accession>
    <name>A9B116_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="12" type="ordered locus">Haur_2656</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2656"/>
    <dbReference type="EnsemblBacteria" id="ABX05294">
        <property type="protein sequence ID" value="ABX05294"/>
        <property type="gene ID" value="Haur_2656"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2656"/>
    <dbReference type="eggNOG" id="COG1197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_1_3_0"/>
    <dbReference type="OMA" id="WAPPCRE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="644"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="826"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1015"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1207" mass="136219" checksum="2D1EA6C72E0969A4" modified="2008-01-15" version="1">MTDHVDTLLADIQALFASEPQLKAALAAAQPNTTRTITPVPSAARRVVAAIATRQHRSSLLIAATPDAAVRMHADLTAWLGENVMLFPPTDTLPYEHMSADIGIVAQRLAVLGRLHASEPICVVASVKALMQPTMTPEEFQFATRLLRQGDQHDPRKLLAHWVSLGYRVGPTAEQPGDLSQRGGIIDIFPPTSDRPIRLEFWDDQLESLRIYDPISQRSDKRVRQIQISPAHEIPFWRRTEAIKRIEQLQIASLRREVQHEWATAREHLETGQRFEGRAFYAPFFRTPHEAAEAGLWQHLPASAIILLSEEHELNAQGIELQSHADLVRSTQIENNELPPDFPFPLIAWTFIRRSIQRWSCLNLSNQPIADDQNDSFVHEINTFSQAASYGGQTDRLFEDLRERLVGGERVVLISPQASRLRELASQHNLALIGEEDGPDVDDPPFQSGTIIIRHGNLSGGFSSDPLRLTILSDSEIFGWQQRRALSTRARKQRTESDRTAFLQSLKVGDYVVHIEHGIAQYEGLSRIEASGAEREFLVLRYASGDKLYVPVDQVDRVSRYIGAGEGKPTLTRLGTSDWERAKRKVRADVEELATELLDLYAARQLVEGFAYSSDTSWQRELEDSFPYTETDDQLRAIEEVKSDMENTRPMDRLICGDVGFGKTEVALRAAFKAVQDGRQVAVLVPTTVLAQQHFETFSRRMQMFPVRIEMLSRFRSASQQKSITERIVKGEIDIVVGTHRILSSDIHFKQLGLVIIDEEQRFGVKDKERLKKLRHEIDVLTLTATPIPRTMHMALSGIRDLSVIDTPPDDRMPIKTYVQPYNEMLVRDAILRELGRNGQAYFVHNRVQSIYTVANRLQKLVPEARIGVGHGQMPEKALEKVILQFFEGLFDVFVCTTIIESGIDVPSANTMIIDDATTYGLAQLYQLRGRVGRSTQRGYAYMFYNPTKAMGEEAQKRLEAIQEATELGAGFRIAMRDLEIRGTGNLLGAEQSGNITTIGFDLYSRLLSQAVERVREERKRGQQQKSGEQKAQRARAVEALRRAAVVSARSSFSGDADDPVLPDAMVSIDLPINAYLPQNYVDDEPLRLRVYQHIAEARSTRDIRMLRQELEDRFGPVPEPAARLLDLLTIKVLALQAGVISIISDDNEITVRLPKSVYLDREQLQRESPRGVVIGPQLARLDRRVLRDDWEVVLRQLLEALNKIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B194</accession>
    <name>A9B194_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4650"/>
    <dbReference type="EnsemblBacteria" id="ABX07281">
        <property type="protein sequence ID" value="ABX07281"/>
        <property type="gene ID" value="Haur_4650"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4650"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_3_0"/>
    <dbReference type="OMA" id="AWRHPEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4707-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="130"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21646" checksum="D65A247AB7B1FBE1" modified="2008-01-15" version="1">MPGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVWQRASTFDNSRGNCAPWLFGIARNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEVVWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIADKLGNPLGTIKTRVRLGLLKLRDLLGTQQWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D0</accession>
    <name>A9B1D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4686"/>
    <dbReference type="EnsemblBacteria" id="ABX07317">
        <property type="protein sequence ID" value="ABX07317"/>
        <property type="gene ID" value="Haur_4686"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4686"/>
    <dbReference type="eggNOG" id="COG3688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048760_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4743-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34547">
        <property type="entry name" value="PTHR34547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29426" checksum="8CE505D81D9B3998" modified="2008-01-15" version="1">MPYIIDGHNLIGQLATIRLNDPDDEAKLVQLLQRFAITRKVSVSVVFDRGQYTQGSLGGGGVSVRFARSPSDADEIIKSQLVRLSRPSEWVLVSSDRAITSVADAVGARVITARDFAALLESMGAADPNAPTHQEMHAHVRQDQLPEWLDFFGIDKESAESKVDLTRKPKPNQPTQQRSATQAKRRSPQAAKPIVVPQPPERWQLPPRRKDQPDPIPRDADGRPRLSRGGKNPQASTGERLHKPPPPVHPDEIDEWLEFFGADEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1H7</accession>
    <name>A9B1H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1214"/>
    <dbReference type="EnsemblBacteria" id="ABX03862">
        <property type="protein sequence ID" value="ABX03862"/>
        <property type="gene ID" value="Haur_1214"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1214"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_4_0_0"/>
    <dbReference type="OMA" id="VQQRKPA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="256"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1130" mass="124734" checksum="39AA9EC5DD6CC4D9" modified="2008-01-15" version="1">MAANPQISSFLPRYVLQRLIEEHQPRQPLAEDQLATVLFADFSGFSRLSEQFAYDQTTILEYISDVLNDSFSQLIDTVIAHGGDVVKFAGDALIAIWMADDLDQLTQNTQLAAQCGLAIQASFNNPSESERLAIRVQIGAGSISSFIVGGVNNHWEQLITGEALLQVHLLGSQSFAGQVIVSPEARSLIREYGLGEDLRAQAFRLTAMSENLPLPMMNQTLPEYPTEQLTPFMPTAVIARINAGLHEWLAELRHLSVMFINVPALSFFTTLEQVQAAVSALQTVIFRYEGSIDKLSVDDKGVSLLAAFGLPPLSHRDDAERAVRSALEASAALSKLSLTHTIGIATGPAFCGEIGNSQRREFTMIGDVVNRAARLMEANLAPILCDQTTAQASQQHVRFQVLPPITIKGKSQPITIYRPQQTNHSPDQIRPRRLIGRRRERGQIEALFNQTQPSSQHVAITGDSGMGKSALLYEAVEIAQHYERQAMLITSSSLRQSAQYPGWRLLLEACLAVEQWPNQAVQSYQLIIQRLQLPDQLAKSVHLLHDVLELPGRAEANTTDHAQQVQIIHELIGHALYQLHAQRPLVLCIDNLQWFDSLALATLELLLQQHDDIILITTAPSAVACLEPQQTIHLQALDPVACIAVVAQSLGVQAIPPSVALFINQRAAGHPLWSIELAQALRNAGMIRVNNGVCKLDQFSQLEKLNLPSTIQGVLVSRIDQLPPQPQLTLKIASVIGHDFSLAVLDAIYPVAHEREHIPAHLDLLLQQGFIHEAAEGYQFSQAIIHDVAYSLLLFGQRRALHRAIAEWYTREHPHLVEAGSSLLAHHWSHAIDPDEPESRQPAIDALRRAGEQTLVRCSYREAIPFFERALHLLAIDDDFASQQQIVRMQFNLSQARWRLGDHSMALTNLDAALVTAQQIGDGIGEADVLRQFGNIAYVQGDLYTAQQHFLASVARARKANYPSGIISGVSNVGVVAFARGDYQVAREAYRDGLAISIEQGHDFGIAVNQLNLGGLAIVEQAWDEARSYLQQALSLGYAKHMTLVCLHSLVALAEWRLATNQAEASANLIQIVLHHEAIDSEIHAAIDKLKPKLIQILGETQWLILSQRPTTPFEQVLPAIMQELATEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J7</accession>
    <name>A9B1J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1234</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1234"/>
    <dbReference type="EnsemblBacteria" id="ABX03882">
        <property type="protein sequence ID" value="ABX03882"/>
        <property type="gene ID" value="Haur_1234"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1234"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_1_0"/>
    <dbReference type="OMA" id="SFIRPNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1256-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="58"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28488" checksum="8E9E4E86059A0C69" modified="2008-01-15" version="1">MSYRKLVLLLAFLLIVPIAIFLVYAFAQGWFFPALWPERWDSELFLRQLRDPQVRRGFEQSLVVATGVSGLALLLGYPAARVLELQQFRGRGLIYGLFFLPTVVPSVATGIGLNIVFLRLDLAGTLFGVMLVHLIPVLPYVVLTLGSSLAHYDRNYEHQAAVLGASPWLVFWRVSLPLLLPSLVVAGVLAFLISWSQYVLSLLIGGGKIITLPMLLFSAASGGNYSLIASLSLIFIAPLLLLLGLVARYLGSPATGATPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K2</accession>
    <name>A9B1K2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1239"/>
    <dbReference type="EnsemblBacteria" id="ABX03887">
        <property type="protein sequence ID" value="ABX03887"/>
        <property type="gene ID" value="Haur_1239"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1239"/>
    <dbReference type="eggNOG" id="COG1088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OMA" id="KLIPLMC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1261-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="5"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="41133" checksum="CDA08CB5DC0E8B72" modified="2008-01-15" version="1">MRIAVTGGAGFIGSNFVRYWMDTNPADEVVVIDALTYAGHLSNLAGYHERANCQFVQADICDYPTMLKVLAGVNLVVHFAAETHVDRSLGEFEMERQFYRSNIEGTASLLRASREAGVGHFHHVSTDEVFGDLDFDDPQKFHETYPYNPSSPYAVSKAASDHVVRAFAHTHKYPITITNCTNNYGPFQTPEKLIPRSIALLLAGQKVKLYTDAEGIPGRNIRDWLHVQDHCEAIALVIQKGRIGETYGIGGEAELSNYHLVETMLDIMSEYLDRTLTIENSVEFVADRPGHDRRYAMDLSKIKRELGWQPRYSFQQGFLETVQWYTSPEGQAWLASLNDRTSDVRANQEQVVAVRENWQAEHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R4</accession>
    <name>A9B1R4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c-type biogenesis protein CcmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CcmB/CycW/HelB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2718"/>
    <dbReference type="EnsemblBacteria" id="ABX05356">
        <property type="protein sequence ID" value="ABX05356"/>
        <property type="gene ID" value="Haur_2718"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2718"/>
    <dbReference type="eggNOG" id="COG2386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079069_0_1_0"/>
    <dbReference type="OMA" id="VKCLAHW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2749-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003544">
        <property type="entry name" value="Cyt_c_biogenesis_CcmB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30070">
        <property type="entry name" value="PTHR30070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03379">
        <property type="entry name" value="CcmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="24486" checksum="AABCCB9325248C84" modified="2008-01-15" version="1">MAKPTLWQAAWAVAYKDLQIELRTRYALNAMALFAVTTAVMVSFRLGPLGLSRDPRSAATLAVLLWIAIFFAAMNGLARTFVREEEAHTATLLRLNVPALAVYLGKLLVNLLILALLETLVTLLFIGLLNVTITKVGLFLATLSLGGVALAGATTILATLVAKADGKGSLFTILAFPLVLPLLIIAVETTELALSGGTWGSAGSGLQLLAAYTIAEHVAALWLFERVWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T6</accession>
    <name>A9B1T6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2740"/>
    <dbReference type="EnsemblBacteria" id="ABX05378">
        <property type="protein sequence ID" value="ABX05378"/>
        <property type="gene ID" value="Haur_2740"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2740"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_905428_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2771-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="193"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="34681" checksum="1DC43BC645E48412" modified="2008-01-15" version="1">MTAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQPKTDTMQTIYSIDEGIENVVPYAWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTRSFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEFEEALLSTVASSVALALDNAQVLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDGSGLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMGLAMLGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X9</accession>
    <name>A9B1X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2783"/>
    <dbReference type="EnsemblBacteria" id="ABX05421">
        <property type="protein sequence ID" value="ABX05421"/>
        <property type="gene ID" value="Haur_2783"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2783"/>
    <dbReference type="HOGENOM" id="CLU_2130037_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2814-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12752" checksum="4ABD2B81C79CC3C4" modified="2008-01-15" version="1">MIRIEENNRPNIKFLNYSLFAGGQGLFFLINRWSGWAWYNGYSRLGRRLGRLVGTATNKADGQKCNPDQAAHTASSSLNDTHQLGRVYPINQFLPTNNSFRIDNSSTNALICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B263</accession>
    <name>A9B263_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4782"/>
    <dbReference type="EnsemblBacteria" id="ABX07413">
        <property type="protein sequence ID" value="ABX07413"/>
        <property type="gene ID" value="Haur_4782"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4782"/>
    <dbReference type="eggNOG" id="ENOG502ZIKF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1426215_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4840-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="21080" checksum="30F3677B7DB46056" modified="2008-01-15" version="1">MTRQKGRGAREQNRADRRNEYATLVAPHFKGLVVPESPADRIILFGDELVDLAVHLARQIPDGQLVLITSEYDRWQAASEALAQFAQASVLQELDELRDPDGFPTEPWSLAVMLVPFQLGSKTVLDLMRNLFGWLRAGSPIYLGGSRMHEWQITSERFSAMAGPLTMLYNGDPVRIAKGMARGGSLVSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B289</accession>
    <name>A9B289_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ParB-like partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4808"/>
    <dbReference type="EnsemblBacteria" id="ABX07439">
        <property type="protein sequence ID" value="ABX07439"/>
        <property type="gene ID" value="Haur_4808"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4808"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023853_0_0_0"/>
    <dbReference type="OMA" id="IALSYQR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4867-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="31"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="35368" checksum="2A79B77C6DF5AD6A" modified="2008-01-15" version="1">MNPKKRGLGQGLGALIRPDPTTSMPMVGALHSVPIESIEANPHQPRQIFTPEALEELSASIATHGILQPLVVTRTATGYELIAGERRWRAAQQAGLSEVPVIIKEVTPQERLELALVENIQRADLNPLEEAQAYQLLHDEFSLSHQAIAERVGKSRPAITNALRLLKLPSPLQQAVMEQQLTAGHLKQLITIDDERTQILAMEQILEFRLSVREAEKMAQLIKHESQTPAQARIAIQQRGAAPRASRRNGAPTPAAPTRNSIPAEPVVPNVDDTAAVDQLTRQLGTKVEVKRQGNGGYVRIDFYSDEQLIALIESLLNGETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F2</accession>
    <name>A9B2F2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1352"/>
    <dbReference type="EnsemblBacteria" id="ABX03997">
        <property type="protein sequence ID" value="ABX03997"/>
        <property type="gene ID" value="Haur_1352"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1352"/>
    <dbReference type="HOGENOM" id="CLU_1336000_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1373-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="23161" checksum="180E7851C58A7E1D" modified="2008-01-15" version="1">MSLKTRSPLGYMHHRNRVLVARGLPQNATVKTRWQFVNRSRLIAEASMLLIWVVLWIANGIATASAVVLGGLWLQYHGIWVHAGVLDWFVIGCLSHVVVSFVGQHLWRGVNVPNELRWYQQVPYFFVHVDRMRLTCAVIVSSLDATATGWYIQTVLNDVFGYRWWFALVSGLLAALVALSAEPMIRQFVRGVRDVLKGTAASCKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L9</accession>
    <name>A9B2L9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha,alpha-trehalase</fullName>
            <ecNumber evidence="1">3.2.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.28" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2832"/>
    <dbReference type="CAZy" id="GH37">
        <property type="family name" value="Glycoside Hydrolase Family 37"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05470">
        <property type="protein sequence ID" value="ABX05470"/>
        <property type="gene ID" value="Haur_2832"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2832"/>
    <dbReference type="eggNOG" id="COG1626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006451_3_3_0"/>
    <dbReference type="OMA" id="TNGVLIW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2863-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005991">
        <property type="term" value="P:trehalose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="PTHR23403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="46325" checksum="80AB59658D8420A0" modified="2008-01-15" version="1">MRQPAITQYIDAYWDKLVRQQPEDQKTLIGLPHQFMVPTHDPTFQEMFYWDSFFIALGLGGTRYEAVIEGMAENMAYLYQRFGVIPNASRYYFLSRSQPPFWTQLIWLAYQTKQAAGDPDSAAWLQRLMALAEQEHASVWLATTHPHQRQVHRGLSRYFDINYLDTLACCESGWDHSTRCNGQWMSHLPVDLNSILYLRECDFAQAARVRDDHAAAEQWQSCADQRAETMQAVFWDAASGFFYDYNYLNEVADLDNPSLAGFYPLWAGWATEVQAAQVVEQWLPSFMRVGGLVTTLKTHASYQWASPNGWAPLQWIVVEGLLRYGYQSQAREVMQAWCTLNETVFERTNAMWEKYNVVDPTGEVEGGKYGSLPGFGWSNAVYLDFKRRLAQPTIERWKLGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Q5</accession>
    <name>GCST_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminomethyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gcvT</name>
        <name type="ordered locus">Haur_2868</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B2Q5"/>
    <dbReference type="SMR" id="A9B2Q5"/>
    <dbReference type="STRING" id="316274.Haur_2868"/>
    <dbReference type="PRIDE" id="A9B2Q5"/>
    <dbReference type="EnsemblBacteria" id="ABX05506">
        <property type="protein sequence ID" value="ABX05506"/>
        <property type="gene ID" value="Haur_2868"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2868"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_2_0"/>
    <dbReference type="OMA" id="MPVQYPA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0032">Aminotransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000114099" description="Aminomethyltransferase">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <sequence length="361" mass="39308" checksum="E5371EA3250BEEFB" modified="2008-01-15" version="1">MKQTPLNARHRALGARMVEFGGWDMPVQYAGIIAEHKATREGAGLFDISHMARFWVTGPDSERFIQLIDTFDISKTAIGQSDYGIMCYEDGGIVDDIFTYHLGPDEWMVVANAGNAEKDWAWLNQHTAGYDVVLTDRSQELAMIALQGPKAESLLAPLTDADVVNLAFHGITKATVEGAAGYISRTGYTGEDGFELFLPAGEIERIWDRLLEVGATPIGLGARDSLRFEPGLALYGHEIERDINPYEAKLGWVVKLDKGPFIGSEALHDIKANGPVRTLVGLEMTGRGIARQGYPVVALDGSELGVVTTGMPSPSLGKNLAYALVKAGSLKIGAEVDVLIREKPVRATVVKTPFYKARYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Q7</accession>
    <name>A9B2Q7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glycine dehydrogenase (decarboxylating) subunit 1</fullName>
            <ecNumber evidence="4">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glycine cleavage system P-protein subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine decarboxylase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine dehydrogenase (aminomethyl-transferring) subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gcvPA</name>
        <name evidence="5" type="ordered locus">Haur_2870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvP family. N-terminal subunit subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2870"/>
    <dbReference type="EnsemblBacteria" id="ABX05508">
        <property type="protein sequence ID" value="ABX05508"/>
        <property type="gene ID" value="Haur_2870"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2870"/>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_0"/>
    <dbReference type="OMA" id="MYDGASA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00712">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006815">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="47725" checksum="04865E1353F414D0" modified="2008-01-15" version="1">MSHYISITESERAEMLKAIGVADVAELFHDVPADLRFPTLDLPAALAEGEMARELRRLSSKNSDVLNYSCFLGAGAYNHFIPAAVDSLLRRSEFYTAYTPYQPEISQGTLQAIFEYQSLMCGLLQMDAANASHYDGATAMAEGAIMAISATRNRRKIVVAPSVHPQYRGVLRSYTQGLGVTITGDENPAASVADAAALVDNETAVFIVQSPDFLGVLHDLKPVAEQIHAAGALLLMVTNPIALGLFQTPGMVGADIAVMEGQPLGIPLSFGGPYVGVFSCTEKLLRRMAGRLVGVTTDLNGQLGYVLTLQTREQHIRREKATSNICTNQGLMALAATIYTSLMGKTGLRKVAELCYQRAHYAAKAIGNLAGYEVLEQGAFFHEFVVRCPRPVAEITQALHAQGIIGGYDLSKDYPHLGNAMLICVTEQNTKNDIDQLVAVLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R4</accession>
    <name>A9B2R4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2877"/>
    <dbReference type="EnsemblBacteria" id="ABX05515">
        <property type="protein sequence ID" value="ABX05515"/>
        <property type="gene ID" value="Haur_2877"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2877"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="RTRGQMW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2908-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="36324" checksum="2565E6BC29091C25" modified="2008-01-15" version="1">MQPEYAIRTVNLQRTYKTKERILKALDGVDLAVRPGELFGFLGPNGAGKTTTIKILTTLLLPTGGTAEVWGFDVLHEADAVRRHINMVSGGESSGYGLLTVRENLWMFTQFHGMDSKLANKRIDELLEVMGLADRAKTRVSFLSTGLRQKMNYIRGLLTDPDVLFLDEPTLGLDVEAARTLRTYTRHWLDTNPGKTVVLTTHYMQEADELCDRVAIISGGTILACDTPTSLKHSLQEDVVFRLFTTPVNPAFLQAVEQIAGVQSISQRSGDQRDELSLILRDDAILPHVLSQLAAHNAGLLSLEKRQPTLEDVFVNLVGHSLSESEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V3</accession>
    <name>A9B2V3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="2">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3380"/>
    <dbReference type="EnsemblBacteria" id="ABX06016">
        <property type="protein sequence ID" value="ABX06016"/>
        <property type="gene ID" value="Haur_3380"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3380"/>
    <dbReference type="eggNOG" id="COG1884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_0"/>
    <dbReference type="OMA" id="CGVAIDS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3417-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="1">
        <location>
            <begin position="38"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="559" mass="62612" checksum="40D6312396C89E6F" modified="2008-01-15" version="1">MFSPEQLAQMRAAQERWNDETLAPTLQKTPERPALFSTISSEPIQRLYTPLDIADTDYQKDISFPGEFPYTRGIHPTGYRGKLWTMRMFAGFGTAEETNARFKYLLSQGQTGLSTAFDMPTLYGRDTDHPLVEGEFGKCGVAVTSLADMDILFDGIPLDQVTTSMTINSPAAIIWAMYIAAAEKRGISRAKLGGTLQNDILKEYAAQNEYIFPIAPSMRLVVDTIEFAAQHMPKWNPVSVSGYHIREAGSTAAQELAFTLGDGIAYVKACLKRGLNIDDFAPRISYFFNAHNDFFEEIAKYRAARRVWARQMRDVYGAKNPRSWWMRFHTQTAGVSLTAQQPENNIVRVAIQALAAVIGGTQSLHTDAMDEALALPSEKAVTIALRTQQIIAEESGVTNTIDPLAGSYFVEALTNRMEAECLDYFRRIEEQGGMEAALEKGWIQQQIADSSYRFQQEVDSGQRGFVGVNKYTVDDPIEIPILQMDPDGENKHMARLNKVRNERDQVRWAEAMDNLRQAAQGEHNLMEPILAAVNAYATLGEMCDVLREVFGVYQEVMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W3</accession>
    <name>A9B2W3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3390"/>
    <dbReference type="EnsemblBacteria" id="ABX06026">
        <property type="protein sequence ID" value="ABX06026"/>
        <property type="gene ID" value="Haur_3390"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3390"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403227_0_0_0"/>
    <dbReference type="OMA" id="SARTFIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3427-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="275"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="332"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="460"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="682" mass="74033" checksum="71366568F355140E" modified="2008-01-15" version="1">MQLRPKIRLPTLLIGVNLAVLIIAIVGIATVAIGLLLELGDDQGLARVRQGVAIAQNDVQRSGNEVLTTAQLLAERPTLARLLQTNDQVALEDFLGQFQATSELAGCAIYQDGQLLIAVGTEIPAMPALDNRALLLDGALLGLAARVPLATDPSVIVAVWIELDQQYQAELSTILSLPVAIVPQQRLTNPNDPLTETQAAALTTNTITDSYLRDQHHYIASAPLLASTGQPIGVVSVTLPDTQIRNSAQRLSEVLLTIALVGGVLAFGLNLLVGRYVGWPLRRLTMAAAQIGRGDLTTPVAPAKGVEVGMLAGTLEDMRQRLRGLTADLQRQQAEANAILAGIVEGVFTVDRDRRIRYLNQQAASMLGIAPEQAIGRFCGDVLQPQLVDGVRPCEQACPIIHARFRGQAQATEHLQLLDGRRRTVIITSAGDVEQNHVQVMRDETDIETSRRLRDTILATISHEFRTPLSAQLASLELLLDQLPQLSTAQIRQLIVSLQRGALRLTYLIDNLLESARIEAGQLTIRRSEIALDGVVEAAVELMLPLIEQRRQQVEVDLPYPLPNVAGDATRLTQVFVNLLANASKFSPPDTTIAIGGEVTSEHLLVWVEDEGPGMPPSPSESPFRLFVRGRNEPEQSGAGLGLWIVQSIIERHNGRIHVPARSLGTRIVIELPRGTDEDFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B366</accession>
    <name>A9B366_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4899"/>
    <dbReference type="EnsemblBacteria" id="ABX07529">
        <property type="protein sequence ID" value="ABX07529"/>
        <property type="gene ID" value="Haur_4899"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4899"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072309_0_0_0"/>
    <dbReference type="OMA" id="KHKAFHN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4960-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735215" evidence="4">
        <location>
            <begin position="25"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="27037" checksum="107413061A7132C5" modified="2008-01-15" version="1">MKPTTIVSTGLLLLALTGCGAPSAADINAEGNALYEQGVYGQALNQYKEAVLMAPDRPEPQVNLGNTRYQMGDYLGAIEAPNNALQTADAATQAIIYYNQGNAHFRLEELDEAIEAYKKALRINPDDLDAKYNLELAQKIQEQQQQQQQASNQQDPNQQPQDGQQDPNQQPQDGQQPEPNQDPSGGGQPPERPQAPPSSMNPDEAERQLDQLERSEERNREDLYDNYAVGADGNPTDSQSGDDEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B2</accession>
    <name>A9B3B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1431"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04075">
        <property type="protein sequence ID" value="ABX04075"/>
        <property type="gene ID" value="Haur_1431"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1431"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_1_0"/>
    <dbReference type="OMA" id="VEPAYEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1453-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="590"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="749" mass="80572" checksum="3D76A02AB88C9051" modified="2008-01-15" version="1">MTASDQQINDLLTQMTLEEKISLTIGQDMWSTHPVERLGLGSINMNDGPHGLRKPPENSSIGIIDAIPATCFPTAAAVASTWDVDLTKAIGEAIAQECLANNVQIVLGPGINLKRTPLGGRNFEYYSEDPVLAGELGTAFVEGVQSHGVGTSLKHYACNNQEFERMTISSEVDQRTLRELYLAAFERVVKRAQPWTIMAAYNKINGIYATEHRQLLTEILREEWGFEGIVVSDWGAVNDKAAALTAGLDLEMPGPALNHVEFLAGLVRKGALSETVIDTAASRMLKIILRGIAQRQPAASYDKAAHHALARRAASESMVLLKNDGILPLQPTAGSTVAVIGNFAQKPRYQGAGSSEINATQVDTPLEALQTWLKNQSVEVNFAAGYDHDGNTNDQLIAEAVAAAKNASLSLVLVGLPDAYETEGADRAHMNMPTGHNQLLEAVAAVQANTVAILINGSAVTIPWLDQVRAVLEAGLAGQAVGSALVDVLSGAVNPSGKLAETFPYDLADTPAFLNYPGEAGVVRYGESLFIGYRYYDVRKVKPLFPFGYGLSYTSFRYDQIALSAASIDEATPLTVSVTLTNTGERVGKEVVQVYVKPSNSAYLRPVKELRAFAKVELAAGETKTVELTLVARDFSLYDQQRAAWRMEGGSYQILAGGCSADLPLVADLTVNEDPRSARKVLTRMSSIKEFLDDPIGAEILHATAGAFIEGQSASTRAIFEPIPLAKFVNFGFFEASQVDEIVAKVNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E0</accession>
    <name>A9B3E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1459"/>
    <dbReference type="EnsemblBacteria" id="ABX04103">
        <property type="protein sequence ID" value="ABX04103"/>
        <property type="gene ID" value="Haur_1459"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1459"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_0_0"/>
    <dbReference type="OMA" id="WAINSYT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1481-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="483" mass="51540" checksum="DCE25C2464A16BC7" modified="2008-01-15" version="1">MRVETTHASAVATSTREKGIILTLLIATFVVILNETIMGVALPRLKDEFQVEASTVQWLTTAYLLVMAVLIPTTGFLIQRFSTRTLFLTAMGLFTFGTVAAAAAPGFEVLLVGRVFQAAGTALMLPLLMTVILVLVPMERRGAMMSTASMVISVAPAIGPALSGLIIQALSWRFMFIFVIPIALAVLAYGYLRLVNVGKLQAASLDRTSILLAAIGFGGLVYGFSRAGEPGSSLTEPIVLAAIGMGLVGIALFAWRQTRLSSPLLDLRVFRFPMFTLSVVLMMVVMVTLFASAILLPFYFQQIRQFNTLQTGLFLLPGGALMGFSGLFVGRIFDRSGPRMLVIGGMVLVVLALWQWTFLNATTSVIWLLSLHVIFSLGLACLFTPILTTGLNQLPQTLHSHGTAISNTLQQVAGAIGTALLITIMSAGQAQPGQTIAPNPLADLTIGIQNAFVVAAGIAVVGLVLALFLRRTGEPSGEPTFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K1</accession>
    <name>A9B3K1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2935"/>
    <dbReference type="EnsemblBacteria" id="ABX05573">
        <property type="protein sequence ID" value="ABX05573"/>
        <property type="gene ID" value="Haur_2935"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2935"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813230_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2967-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732431" evidence="1">
        <location>
            <begin position="28"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="37080" checksum="A3EF08B89F5990EB" modified="2008-01-15" version="1">MHLKKWSLIGAALVGLLLAQPITPSTASPQALDIATRGSISCASPTTDRIDCFVVGDDKQVWQHSWQSGFGWGTWVGLGFPYFTIDPGGGVSAVARDGTTIDIFVSGKDGNFFNLYQRTWNGTTWSDWTSLGGPGSWDIYELSCTSASATNISCFVRASDNHLWQKTWNGSNWSTWSDLGTFVNGGPFKGLASSNYNADSILLFAIGSDGHAYRRFYESGTWSGWLDDGGPTGSSFDQVNCQDQAGSKITCAFTDTMGDVWYRTWDAGWSAFTQLATPPSSAKGVAVAHYSSLGRVIVTNGFDGRLYRTFQPDPTSAWASWLDDGRPQDLQIFLPMAIKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K3</accession>
    <name>A9B3K3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2937"/>
    <dbReference type="EnsemblBacteria" id="ABX05575">
        <property type="protein sequence ID" value="ABX05575"/>
        <property type="gene ID" value="Haur_2937"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2937"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_0_0_0"/>
    <dbReference type="OMA" id="ERHTEIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2969-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="149"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="30293" checksum="F3235BB9295B51EE" modified="2008-01-15" version="1">MSFGSVFIAMEESMSDQLIDQALVEIPGYRKLPLTKQQLAQRVLITVHAFGMDLDEEEPHFYRTHLEEGAYQRAMQGLPIDDFEQLVLLWHRRGIEMLMAKFEHPAEHVALLRQTLKVIQSGLAGLYRGYDRARIGQLDRQQAILSELALPIIPVYKHILAVPLIGVIDSSRAQQMIERLLDEITTLKAQMVILDLTGVPLIDTGVAHHLLKTVHSARLLGARVIIVGIRGEIAQTMVHLGIDLSEITTRANLQAGVEYALACTGFAIRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3M1</accession>
    <name>A9B3M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2955"/>
    <dbReference type="EnsemblBacteria" id="ABX05593">
        <property type="protein sequence ID" value="ABX05593"/>
        <property type="gene ID" value="Haur_2955"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2955"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_0_0"/>
    <dbReference type="OMA" id="VAFACAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2987-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="22012" checksum="463781D5A73BA9FD" modified="2008-01-15" version="1">MMEERYHHGDLRQALLTLAKQQLTSQGIESLSLRAISREAGVSHAAAYRHFPNKEALVAALACAGFEQLQIFVAGEVAQYSEDPTEQFFQCGIAYVTFAINNATLFRLMFGVSGVDRLQYPATHAAAQASFGVLVGTIERGQAAGLIGSGEPRQLAFTAWAAVHGLATLALQDQITPQGTIDPERLVRNSAKLLWHGLKYGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N3</accession>
    <name>A9B3N3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2967"/>
    <dbReference type="EnsemblBacteria" id="ABX05605">
        <property type="protein sequence ID" value="ABX05605"/>
        <property type="gene ID" value="Haur_2967"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2967"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108925_0_0_0"/>
    <dbReference type="OMA" id="VWDYEVY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2999-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="115"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="115"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="24887" checksum="16663358892A82FB" modified="2008-01-15" version="1">MSDQPVPSLTIKNQDVPPRLMSWEQTILTIGRDVANDIVIDHRLASRRHARLERDEAGCYIRDLDSTNGTYLNGVKVNGLAPLRNNDEVWVADTVIIFRDPEATMKGTPPPVVMHRIATQDQAELHVDSAAKEVYVRGKRLDPQLTAKEFQLLELLYNRRGEVVSKEQIAIGVWDYEVYDYNAIDALIYRLRQRIEIDPSAPRFVLTVRGFGYKLSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B459</accession>
    <name>A9B459_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsF</name>
        <name evidence="6" type="ordered locus">Haur_4962</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4962"/>
    <dbReference type="EnsemblBacteria" id="ABX07592">
        <property type="protein sequence ID" value="ABX07592"/>
        <property type="gene ID" value="Haur_4962"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4962"/>
    <dbReference type="eggNOG" id="COG0360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113441_5_1_0"/>
    <dbReference type="OMA" id="REGYYLM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="109" mass="12604" checksum="FF1BCD56EB6A4F93" modified="2008-01-15" version="1">MFHVGENIVRAYEMMTVLRPDLGGEEELNTTIETIQGYIKAQGGEVASTEQGAPWGRRKLAYPIDDYTEGFYFLTHFTLNADRVTEVERHLKLAPQILRYLLIRDETKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D5</accession>
    <name>A9B4D5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0040"/>
    <dbReference type="EnsemblBacteria" id="ABX02692">
        <property type="protein sequence ID" value="ABX02692"/>
        <property type="gene ID" value="Haur_0040"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0040"/>
    <dbReference type="HOGENOM" id="CLU_579737_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-40-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="471" mass="50092" checksum="1A5D0632B8290F64" modified="2008-01-15" version="1">MHHLPTFRTLGLLGLLGLLLVAIQPSQAQQPLSPKIRPEPSLSNRQPLLSAAPQGGSEWLVPCAANAENWQSSVREDTAALNCEIYVPESAMIFVMATGSFSMQTNAVTNTYEGRIGLTLDGVLRESSNRWGNVYALGQLNTGETSIFASTTVFTASAGVHTVSLVGGFVGYGPLTLNNAQLSVLAFPTNSANIRVCATDTGLGVWRATPTMSTIRSCSFNLPSNSTVFVSADGSALPIPGNEVALQFRLGVDEATTGDVRTDRYVDVDSLEPNNEQIDGNDISTSIAASFNLTAGNHTINFLGNGSGSNQAYLSRSSLAVLAFPSGSPFRTCTSMNDTSTFFSNSEFSSWANCLLTVSGAHRGIIVGNVTVGQQNGEPQVRTRLRANTEVVLGSTRTSDLTIFRMVGGQGDDKTMTSVGMSELAGGLNIFNFDGYPSNSSTVRMIDPNIHVLAFPDPFRYKQYTPLALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4K6</accession>
    <name>A9B4K6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1527"/>
    <dbReference type="EnsemblBacteria" id="ABX04171">
        <property type="protein sequence ID" value="ABX04171"/>
        <property type="gene ID" value="Haur_1527"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1527"/>
    <dbReference type="eggNOG" id="COG4668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072531_3_0_0"/>
    <dbReference type="OMA" id="IDWAGNE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1551-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="16599" checksum="5E328456A45C0ECF" modified="2008-01-15" version="1">MAILSSETIRLGASAASKQEAIQQAGALLVASGCVAANYVDGMLKREQVISTYLGNGVAIPHGQHENMADVIRTGIAVVQFPAGVEWEPGELAYLVIGIAANADEHVGVLANLAEVIEDEAIVQQLAQTSDPSQILEQLGRAREEEAYDEERHHAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q5</accession>
    <name>A9B4Q5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1577"/>
    <dbReference type="EnsemblBacteria" id="ABX04220">
        <property type="protein sequence ID" value="ABX04220"/>
        <property type="gene ID" value="Haur_1577"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1577"/>
    <dbReference type="eggNOG" id="COG4753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139202_1_0_0"/>
    <dbReference type="OMA" id="EIDGCIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1601-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13136" checksum="599601CF7D056603" modified="2008-01-15" version="1">MNNIKQSLEAAMNIDGALGVALVDYTSGMTLGTAGGNSALNLELAAAGNTEVVRAKMKVMSRLGLKDQIEDMLITLGTQYHLIRILQKKPSIFLYLALNKPTANLALARIMLSEIEEKIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W9</accession>
    <name>A9B4W9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3054"/>
    <dbReference type="EnsemblBacteria" id="ABX05692">
        <property type="protein sequence ID" value="ABX05692"/>
        <property type="gene ID" value="Haur_3054"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3054"/>
    <dbReference type="eggNOG" id="ENOG5032JAA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1394676_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3086-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="21462" checksum="B736CAA3132DBBEB" modified="2008-01-15" version="1">MSNQPPYGQQPPQQPGYPPQQPYGQQPGYPPQQPGYPPQQPYGQQPYGYPPQPQKRSGCLKWGIIGSLVLLLLCGGGGFWLYKFTLNTIGTVNTSLDGFMKAGAANDVNAAKAFVDSSFITDEQLENLFSQRELFEGYSSIEDLPASTNANSSTGQSTTLSLQGTINYSDGMGTYDVQYNLEGEIWKIRYVNIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z0</accession>
    <name>A9B4Z0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05713">
        <property type="protein sequence ID" value="ABX05713"/>
        <property type="gene ID" value="Haur_3075"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3075"/>
    <dbReference type="eggNOG" id="COG2251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_491572_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3107-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="374"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="554" mass="62955" checksum="B63134B2F9D2BC09" modified="2008-01-15" version="1">MLRVSDALRVLLQNQTVVGNDWLPPTKIRSLYLNDPAAIWLEHHGAAHGFAPETLSYAFIDFLAEKGHQFELAWLQRVAPNAVQVCVEPYEGREAHRVAQTLDLIEARTPVIAQPALWWPAERIFGTPDLIVLSSWFRQQYPELAHLVGETEHYLVLDLKFSSNLEKREKAADLSCYSAQTRMYSYMLGQIQGIMPQHAFLITRDRLHNPISIPIEAQLGQPLDADIRQNCERYFEIVRDGGQYLPWNDPIVQLNPNVNDERWGKARAQIRQRQPGGEMLRLWNIGAAAQQKLVKAGITSLSSLMNAASQSLPKGVMKYPDPMKAIMQANHTGLAQRAQGIAPTTRPYEFFVDFEFFSNLNVNFEQQWPTLQGTPMIFMIGIGWLANGEWHYHECIAEREDHLAEQAILAEFIAVLQAQTNQQLDQAVLYHWHNAEPVECRHAAARHQLPSDHLLLNLPWFDLKNVLVDNACAVPGAWDYSLKSIAKALAALDAQYDPAWPSDLADGSQAQLVGWYAYRQPNPRTSAEMQLLSRYLEADCRATWKILAWLRADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B525</accession>
    <name>A9B525_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3526"/>
    <dbReference type="EnsemblBacteria" id="ABX06162">
        <property type="protein sequence ID" value="ABX06162"/>
        <property type="gene ID" value="Haur_3526"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3526"/>
    <dbReference type="HOGENOM" id="CLU_1914171_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3563-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="15392" checksum="FADB653BB595485C" modified="2008-01-15" version="1">MTILAEPLLPETTRRVGSIVLLWHDLLEDTNADLLENTPEQVRQLVQEMTFDDFDHEMRDLWQRSDLTKLFKLYDKTSQFFDAIWLRDARYAQLLQHTQQLISFVRETYGELNIVKVAQALAVPRVTAAQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B553</accession>
    <name>A9B553_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3554"/>
    <dbReference type="EnsemblBacteria" id="ABX06190">
        <property type="protein sequence ID" value="ABX06190"/>
        <property type="gene ID" value="Haur_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3554"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914568_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3591-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="97"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="319" mass="35523" checksum="B1AEC8C7D0BCACCA" modified="2008-01-15" version="1">MIKRGLIYLAWLGVVPCSLWSLLRWTALATTPQGMVLLVFDAWVYASLLPIALLAVSLRRNYLLGVLGLNMLVVLGLYGGRWLPQSANSTPQDLRIMTWNVFYNTQDIAGLAATIRQQQPDIVVLQEYNFQLDPQLPEALEDLYPYAALDPHSGAGGLATLSRWPLRELAPVARGVDSCGCQYLEIATPNGPTRLINTHPHIPLASFKGIYTKTQQDPTFDHLLKLIADQSQPLILAGDLNTTERQPNYLRLRQQLGDAYQQQGWGLGYTFPSNGAIPKAVRLDYIMPNAHWQPLRAWNGTANLSDHGFVVADLQRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B566</accession>
    <name>A9B566_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3567"/>
    <dbReference type="EnsemblBacteria" id="ABX06203">
        <property type="protein sequence ID" value="ABX06203"/>
        <property type="gene ID" value="Haur_3567"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3567"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_0"/>
    <dbReference type="OMA" id="CFITNSG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3604-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="122"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="40985" checksum="96A8BFE85CEC9C53" modified="2008-01-15" version="1">MDFQLTQEQQELRQSVREFAERELLPKAKDVDEKAQIPASTWQKMADMGLMGLPFAEELGGAGADAISAALAVEEIARCCGSTALSYAAHVGLGSAPIAMFGNDQQKEQFLRPAAEGRYLGAFGLTEPHAGSDAGSTRTTAVRDGNEWVINGAKMWITNAAEAGHLIATAITNKDRGKRGISAIIIPKGTPGVHFGSPEHKMGLRGSNTHAITFDNVRVPLENLLGAEGDGFVQFLKVLDGGRISIGAMAIGLGVAAMEAAVSYARERQAFGHAIGSYQSISNMLADMDTELEAARLLILRAAWLKENGKPFTREAAIAKLYASEASERACRNAVQIFGGYGYSSEYPVERYYRDTRLLTIGEGTSEILRMVISRGLLGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C9</accession>
    <name>A9B5C9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0102"/>
    <dbReference type="EnsemblBacteria" id="ABX02754">
        <property type="protein sequence ID" value="ABX02754"/>
        <property type="gene ID" value="Haur_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0102"/>
    <dbReference type="HOGENOM" id="CLU_2617162_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-103-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="78" mass="8716" checksum="E8DE5C4A656B5CC1" modified="2008-01-15" version="1">MPDYLYDLEAQELANGDWALVIHCEAAYAQTVNIATPNFAIERRFDATGYAAVTIPRQQFNGINASDLQIQIQTKINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E0</accession>
    <name>A9B5E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0113"/>
    <dbReference type="EnsemblBacteria" id="ABX02765">
        <property type="protein sequence ID" value="ABX02765"/>
        <property type="gene ID" value="Haur_0113"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0113"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_639011_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-114-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018656">
        <property type="entry name" value="DUF2087"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09860">
        <property type="entry name" value="DUF2087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="235"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="47964" checksum="D79A4423DB20CE90" modified="2008-01-15" version="1">MQLQSSAVTDSLNTLQLLNRAATIRGASAWVQRTAQALSAKQLADNQLVASLGFGLLPQNPSQPMDDFLAELGSSEPNQWVAQLQQHLLELSASAGPLTSERLWQALRNAGIYSELATQQELLAAMQQPDQLLARVCQHLEHMWQLCLQAEWQQAQTAISQLNRQLQAQVPNEAALKGFRQSLGYAVNQEWQQLQGQRQIVLFAATQNGSLTTFLADRQRLWVGIGFGISNELQPRVVSRNELLFRLQALADAARIQIMELLAQGELSAQAIISQTQLPQSSVSRHLNILRNAGFVQERRAGGATKSYRLVTSHIGATLAALEQTLNQPSASPSSSAQSASAVPTSIQRFFNREGRMVTWPSKHIDRIPILEYFAQQFEFGREYSEREINELLKPHTGSDVANLRRYLIDVKLFERDGTGSRYWRKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F9</accession>
    <name>A9B5F9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0132"/>
    <dbReference type="EnsemblBacteria" id="ABX02784">
        <property type="protein sequence ID" value="ABX02784"/>
        <property type="gene ID" value="Haur_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0132"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_0"/>
    <dbReference type="OMA" id="PMWGEVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-135-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="23914" checksum="8E28C3B835AD363B" modified="2008-01-15" version="1">MTKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNASDPAIVQQAIDLAQQAGQGHIDGLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQAALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFLQALREELRPQGVRVTAVVSAAVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S5</accession>
    <name>A9B5S5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1665"/>
    <dbReference type="EnsemblBacteria" id="ABX04308">
        <property type="protein sequence ID" value="ABX04308"/>
        <property type="gene ID" value="Haur_1665"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1665"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_4_0"/>
    <dbReference type="OMA" id="ITVQKAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1689-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14930" checksum="5CE6355C96DC0AD0" modified="2008-01-15" version="1">MNIHSDLSISRTDGRPMYLQIIEQIKQRIAIGDWPAGSEIPSIRQLAIDLRISVITVKRAYFELEHEGIIVTQHGKGSFVATNTQLSRQLWEDELDSYLEQVARLAALLGLSNEQLIHRLQAAAAQQQQELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V2</accession>
    <name>A9B5V2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3107"/>
    <dbReference type="EnsemblBacteria" id="ABX05745">
        <property type="protein sequence ID" value="ABX05745"/>
        <property type="gene ID" value="Haur_3107"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3107"/>
    <dbReference type="eggNOG" id="COG1045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_10_0_0"/>
    <dbReference type="OMA" id="GDDVMLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="27599" checksum="455B7783570443CE" modified="2008-01-15" version="1">MRHWWRLVREDIRTILHNDPAARSIFEVLLYPGFQAVQIHRLTHWLWGLNLPFIPRLLSQITRFFTGIEIHPGATIGQRLFIDHGMGIVVGETAIIGDDVVMYQGVTLGGTGKETGKRHPTIGNNVVIGVGAKVLGAITIGDGARIGGGAVVVKPVPAHSTAIGVPARVVATRDPQTGQTNRVEMLPDPEGAMLRSLHESVQHLNQRVIELESAMGSQAYHIAALSAQRTNGDDPFDCLDDLQSYEMHYADGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W3</accession>
    <name>A9B5W3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3118"/>
    <dbReference type="EnsemblBacteria" id="ABX05756">
        <property type="protein sequence ID" value="ABX05756"/>
        <property type="gene ID" value="Haur_3118"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3118"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_397288_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3150-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731908" description="CHAT domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="356"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="693" mass="76579" checksum="FA5788D62EED07D9" modified="2008-01-15" version="1">MVAPSALALILPAGMPLATALMIVNQRQIDWVVITPTPNPKEGDAATLIAVAELKQSNVSVVGALAGLTVTITRIFPDRTVHWQSEAITTKQNDDRRGDNEGIEPEPTTPRVVNAALYYADDPPDLVPPTTTLAVASRYHLRINIGERRSDSRLTDAQALPTPEISEDLPLFISVSSRGEYMVFDAPMQRLSLPPVGDSASLQFSLTAKQAIDDIPIWINVYYNWTLLQTLELHFKITPVEGDLAAPLLARVSYSRTAGFADLVAIRPKKITCKLTGDGEFYRMSVAWPDEGTSTRREQRGLNLVLPINAASLSNEIVQARNTLYDITWQPSYRQGSRGKLAERRESLYQLAVVGNRLYAALFAPSGASAEQAESLAALRTWLETISADQTLPALQIIHEGMPSGVPWGLLYPEPVNDPNNVDLNKFWGCRYRLEIMTPQLAQNAQQAPTAQAQLQISGGTYNFRVPIADTVVDVTQQHREALQTWSTTRGNVALDLRESGDKNSLGGLFGKSDIVYMYCHGHTAKTPDDTSDWLAKFRDQMARLDDNVRSNYSDLLSLSQKEYQPSDPNISDSWLKWNQSLLPLRLLSQWGLKLERKPLVILNMCESAQVLPTLSSGFIPFFSQLGARGILGTECPMLAPFAAAFGQKLIERLGQGEAIGDILPALRRHFIEEERNPLGLAYTYYGDADAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B679</accession>
    <name>A9B679_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3654"/>
    <dbReference type="EnsemblBacteria" id="ABX06290">
        <property type="protein sequence ID" value="ABX06290"/>
        <property type="gene ID" value="Haur_3654"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3654"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="DVWVPPD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3693-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="24377" checksum="A636C338D8BD7404" modified="2008-01-15" version="1">MESISVFLVDDHLVVRQGLRDFLELQDDIEVVGDSGMPVEAVGQIKQLLPDVVIMDLVMPEIDGVEATRRVKAVSPTTQVIVLTSFSDDEKVFPAIKAGAISYLLKDVSPLELARAVRSAKRGEAVLHPEVAAKLMQEFSAPRNNDPDAEALTEREMDVLRLIARGHSNREIADSLIISEKTVKTHVSNILSKLHLADRTQAAIYALRQRLVPMDDPLPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F3</accession>
    <name>A9B6F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0204"/>
    <dbReference type="EnsemblBacteria" id="ABX02856">
        <property type="protein sequence ID" value="ABX02856"/>
        <property type="gene ID" value="Haur_0204"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0204"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091262_1_0_0"/>
    <dbReference type="OMA" id="AVTTNHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-207-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025722">
        <property type="entry name" value="TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13972">
        <property type="entry name" value="TetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21996" checksum="F9EFD4B45E322E93" modified="2008-01-15" version="1">MSKRDLILSTALELFNQKGTAEVSTNHIAEACSISPGNLYYHFRNKAAIIQALFEQLYAAWDTELSLPNDHTPQLSDLTNLVETNYQIIWRYRFVYRELVALLRQDLALHASFLSTRQRGFSGFQQLVEQFIAAGIMRPIEAKTLDQLMQICWLISEFWLNNLEIQQQSIEPSTINSGVSLMLRVLQPYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F6</accession>
    <name>A9B6F6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0207"/>
    <dbReference type="EnsemblBacteria" id="ABX02859">
        <property type="protein sequence ID" value="ABX02859"/>
        <property type="gene ID" value="Haur_0207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0207"/>
    <dbReference type="eggNOG" id="ENOG502Z8NV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_724956_0_0_0"/>
    <dbReference type="OMA" id="DHVHFID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-210-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021445">
        <property type="entry name" value="DUF3095"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11294">
        <property type="entry name" value="DUF3095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="417" mass="46399" checksum="3A8BCA4A32C13C12" modified="2008-01-15" version="1">MAHNFYATLPIITDFVQITDANCYHRVPDDWVIVVSDIEQSTKAIGEGRYKDVNFIGASTIVALLNLQPNLDIPFVFGGDGATVLLPPWLVEQAKPALQAVQHLSESIYNLHLRVGIMPVSEVYAHRYQLEIAKFAASDNYAQAMINGDGLTFVEQTIKDPVAGAKYLLAAQSSDQPGLLDGLECRWQEIPSRYGETVSLLVRAEANTTTQRNAINRQVIEQIEAIYGADDSHHPVDVQQLSLTLRIQDLWGEARLRGGTSKLQQLRYLNNIWWLNVLGKLLLATGAKTELTDWAEYPQILQASTDYRKYDAMLRMVIAGTPEQRQQLEQFLNAERAAGRLNYGLHVSDSALMTCIVFERMGRQVHFIDGNNGGYAKAADQLKQQSHYLEPPVTTKPVSQPKTGLLGDTSSPSWGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q0</accession>
    <name>A9B6Q0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Haur_1716</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1716"/>
    <dbReference type="EnsemblBacteria" id="ABX04359">
        <property type="protein sequence ID" value="ABX04359"/>
        <property type="gene ID" value="Haur_1716"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1716"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_2_1_0"/>
    <dbReference type="OMA" id="VCFEGTV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1743-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="2"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="443"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="483"/>
            <end position="490"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX04359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="745" mass="81939" checksum="47C6092974E2AF0D" modified="2008-01-15" version="1">MMQDRAFIEVYGARENNLKNISLNIPKQRVTVFTGVSGSGKSSLVFDTIAAEAQRQLNETFTFFVQGFLPHYGQPDVERIEHLNSPIIIDQKRVGGGSRSTVGTYTDIAVLLRLLFSRIGQPYVGPGYAFSFNTPQGMCPECEGIGKTVQLDMDKLLDRSKSLNEGAILHPEFKVGKWMWKMYPLSGLFDNDKPIQDYNEQELQAFLYGADLKVSWGEFSSKYEGLLERFERMYLKKDAAAMSDRNRAVFEQFTSSQICPVCHGGRLTQAALNCRIAGRNIAELADFEATDLISFLADVTDPIGDRVAAKLLERMQQLVDIGLGYLSLSRETSTLSGGESQRVKMIRHLGNSLTEMLYILDEPSVGLHARDVARLNNLLQQLRDKGNTVLVVEHDPDVIAIADHIVDIGPRAGVHGGEVVFEGSYADLKRSNTLTGSYLQQVVPTKQHSRQPTGYLPIVNANLHNLKNVNVNIPTGVLTVVTGVAGSGKSTLINEVFLSQHPNAIVIDQSRVTANSRSAPATYTGIMDDIRQTFAKANGVSASLFSFNSTGSCDNCNGLGLVYTDLAFMEGISSTCEICEGKRFKAEVLEYRLRGKSISDVLDMTAEEALDFFNEKKIKPVLQAMNDVGLSYLKLGQPLSTISGGEGQRLKLATELHKKASVYVMDEPTTGLHRSDIGLLMGIIDRLVDLKNTVILIEHHLDIIRQADWIIDIGPEGGSAGGEIIFEGPPMALKTCQRSITAKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T0</accession>
    <name>A9B6T0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin--nitrite reductase</fullName>
            <ecNumber evidence="5">1.7.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1746</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.7.7.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1746"/>
    <dbReference type="EnsemblBacteria" id="ABX04389">
        <property type="protein sequence ID" value="ABX04389"/>
        <property type="gene ID" value="Haur_1746"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1746"/>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015667_2_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1773-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048307">
        <property type="term" value="F:ferredoxin-nitrite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="55"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="130"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="311"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="388"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="553" mass="61468" checksum="5FAC3F6383D96CE4" modified="2008-01-15" version="1">MTATTPKLNPVELQKLEKDGLAVLEDIYRYAQSGDINEVTESDMNRFKWYGLYHDKPKDGFFMLRVRLPGGIMTADQADAIVHLAETVAPGRVEITTRQTFQLHTIALRDIPTVFETLESVGLSSIEACGDVPRNVVSSPVAGIAADEWIDPRPFFKALDEHFAYNTDYSNLPRKYKVSVAGGGLDATQAPINDLSFTPGRKEIDGEIVLGYNVWVGGGLSHEPHLAQNIDVFVPADLDAVVEIARAITLVYRDFGYREKRNHARLKYLIADWGAERFREEVVNYLGHPLERAATDVPPAVYSGDVVGVFRQKQPNLYWVGLLVPTGRITPAQIREAARLSREYGQSEIRLTHSQNLLLPYIPEARLDALLAEPLLQELQPNGPRIQRTVVACTGLPYCNFATIETKEAAWQLAGALDQKVELDVPLRIHLSACPHSCSQHSIADIGLQGGVIRNPDGSKNKLPATDILLGGALGDDATIGRRVATKVPWSELADRLGNLVTTYQAQRTSPEDQFRHWAKRQTDDQLRVYLGFGEPETEEGVWTEEGSWNKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B700</accession>
    <name>A9B700_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3231"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05868">
        <property type="protein sequence ID" value="ABX05868"/>
        <property type="gene ID" value="Haur_3231"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3231"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_19_2_0"/>
    <dbReference type="OMA" id="CAFRREA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3266-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="35193" checksum="F1EEE81DF59416B2" modified="2008-01-15" version="1">MTYLSLICTVKNEADNIADLLDSMLAQSRQPDEIVVNDCGSTDSTAAIVQTYIERGAPIRLVHGGFNISSGRNNAIVHAQGDLIASTDAGLALDRTWLERIIAPLEADQADLVAGFYQAAPRSDLETAIGSTNYPLAEEVDPSRFLAAGQSVAFRKVVWQTVGGYPEWLDHCEDLVFDRAAVAAGFRSTAVLDAVVHFQPRSSFRALFRQYFFYARGDGVANLWPLRHAIRYATYLGLLLLIRNLPQRPWLLGVLGLGIAGYTRKPYRRLWRATKGWSFTRRSKTLGLPPLIRMVGDLAKMLGYPVGWLVRLRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B723</accession>
    <name>A9B723_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3254"/>
    <dbReference type="EnsemblBacteria" id="ABX05891">
        <property type="protein sequence ID" value="ABX05891"/>
        <property type="gene ID" value="Haur_3254"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3254"/>
    <dbReference type="HOGENOM" id="CLU_2105605_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3289-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="115" mass="13416" checksum="4A6512AD3995FCAC" modified="2008-01-15" version="1">MRLKSRSRQMIKQRLTILGYGLIGLLIEFCYLFPSSEYRSAQSIPVYDPDTVLVIQWFVAGLIVPVSFLLVRAIRRRNQRFRWVKYGLLLVALALLSWHWFTLNSHSYPFPAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B756</accession>
    <name>A9B756_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S16 lon domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3703"/>
    <dbReference type="EnsemblBacteria" id="ABX06339">
        <property type="protein sequence ID" value="ABX06339"/>
        <property type="gene ID" value="Haur_3703"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3703"/>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048359_1_1_0"/>
    <dbReference type="OMA" id="MLDHTRK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3745-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="24242" checksum="896BCA6C094961D9" modified="2008-01-15" version="1">MQRLPLFPLNVVLFPGAQLPLHIFEPRYRTMISRCLEESKPFGVVLIREGVEVGGSAVPHMVGTTADIQSAYRLADGRMYIVTEGRQRFRINYPLSVDPYMVAMVTMLDDDVNDRHQADELTALYSQYHRTVAAATGMRSNAIDLPSEPVSLSYKLADSMQMALPIKQRWLESDLDQRIHELIEALQFELALLPNIPPDQLDREPPFENTSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C1</accession>
    <name>A9B7C1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3768"/>
    <dbReference type="EnsemblBacteria" id="ABX06404">
        <property type="protein sequence ID" value="ABX06404"/>
        <property type="gene ID" value="Haur_3768"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3768"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518539_0_0_0"/>
    <dbReference type="OMA" id="SHERNID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3810-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="332"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="448"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="481"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="525" mass="57043" checksum="1C6EC0150D6D5E95" modified="2008-01-15" version="1">MNSITIDERLFEALRSGQSLIATEILAAHPELATTRFDPIDQSLSVTSFVCHPEQYGNARIGQSPLHLAAWNGEQRLVKQLLELGADPNARDRQGGTPLHAMVRWVTRPDIVGMVLERGADINAVDYAGQTPLHLAASCIRRPGHQWGNHTDLCNFLLAHGAIADIFAAVMLNLTDQAAMLLKQNPELVHARTTGNQTHPESATPLHIAVDRGKQAMAEMLLDYGADPNSLDARGRPALYLAAHIAGTRKLEPTPELVDLLLQHSTATPIFNASLIGQCAELRELLIHDPAQIQALDQAGYTALHLAAWNGQVAAVAELLAHDADIAARTKRNETALQLAITYGHHATAELLLNHGATPDIFSAVILGRIDLLEQLLDHQSELASTTNRYGRTPLRLAIEREQTAVIDYLIGREVKPDLWMAAGMGDFARVEALVETDRHALHQRDQWGYTALHWASKSGQLAVIEYLLEQGAGLEPRGSDGGTPLTLALWHEQSAAARLLVASGADIDALDNWGGSPRNQVATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7G7</accession>
    <name>A9B7G7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recG</name>
        <name evidence="9" type="ordered locus">Haur_0288</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0288"/>
    <dbReference type="EnsemblBacteria" id="ABX02940">
        <property type="protein sequence ID" value="ABX02940"/>
        <property type="gene ID" value="Haur_0288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0288"/>
    <dbReference type="eggNOG" id="COG1200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_7_1_0"/>
    <dbReference type="OMA" id="DNGFQAC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="377"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="600"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="832" mass="92818" checksum="8F9A96E27B308990" modified="2008-01-15" version="1">MFFVLMVMQANQHIIELGKTLAAEEKAGCDDTATDHGISIFLREWQAQHPQALHEPVVQGVLDALDGYSELSHAEREARLSVALDRLRNLFRKQPKAPAEPVGAVPPIDTLLKTLQGIGPSTARSFAKLGVHTLEDLLYHVPHRYDDFSKRKQICDLVVGETDTVIVTVDAIKSFNAKGRQGVEITVGDDTGVLKASWFRGTWMAKQFREGMRIVLSGKVSMFREMKSMSNPQWEPFVEDDLVHTGRLVPVHPLTKGLQDRNARQVIKRVVDAVTPTLSDPLPIELRERAGLLPLGVAISQIHFPDSWAMVQRARQRLGFDEFLYIQLGVLQRKRLYQGVQGQPIAFNQAIHDAYLSSLPFALTNAQTRTFNEICRDLERPVPMTRLVQGDVGSGKTAVAAAALVQAVAAGFQGAMMAPTEILAEQHYRGLKKLLANVKIPGRETNSNGDWRDELDQEKRNRLAQIKQLLMLADEPEPEPGGIRVALLTGSLKARQRREALKLIADGEVDIIIGTHALIQANVDYQALGLAVVDEQHRFGVEQREALKRKGFNPHLLVMTATPIPRSLALTIYGDLDVSVIDERPPGRQPIRTKWISSGERSKAYKHMRKEIAAGRQAFVICPLVEESEKLEDVKSAIVEQEHLQHEIFPDLKVGLIHGRMTSSEKDTIMAQFRDREFDILVATAVVEVGIDIPNATTIMIEGAERFGLAQLHQFRGRVGRGSHQSFCVLVSDKEDNDVTVARLSSMEESEDGFRLAEIDLELRGPGEFFGIRQSGTPDLKVAQLTDTRLLHAARIEAERILKLDPELELPEHAKVREKLQAFWAGMETQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I4</accession>
    <name>A9B7I4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0305"/>
    <dbReference type="EnsemblBacteria" id="ABX02957">
        <property type="protein sequence ID" value="ABX02957"/>
        <property type="gene ID" value="Haur_0305"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0305"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_369107_0_0_0"/>
    <dbReference type="OMA" id="QQVSHML"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-308-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="505"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="754" mass="82840" checksum="1ABCFF79CC3836C9" modified="2008-01-15" version="1">MTERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDAIAVWFYSPTSHRYLLSHFNNANHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARNADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGNGRPSGVIELFSSKPSINANSAAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIEVVSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVISTSDLGEDIMGRAAMPLLAGGTIVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRLYEESQRERQRLGTVIESIADGVAICNGVGELILANETAAGLVEISILPTLATSSESGARYLDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFDGAVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRGFITLSQQVNIMVQLVDNLLDVSRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHFEQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQVFSDEQFGYVQVDDQGPGIPQGQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAIPRFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P5</accession>
    <name>A9B7P5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1780"/>
    <dbReference type="EnsemblBacteria" id="ABX04423">
        <property type="protein sequence ID" value="ABX04423"/>
        <property type="gene ID" value="Haur_1780"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1780"/>
    <dbReference type="eggNOG" id="COG3500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_868177_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1808-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="34750" checksum="E2DAAB1D143869C8" modified="2008-01-15" version="1">MLVKYRITIGSSSFSADQADWLVSCASYGSLRSPINRCSLVFASKSGLNAKLGDPVSVDLGDADSLQRVFTGCVASCQANLHTITVEAYSSAQLLTKMHLNALYEQRSGGAIAKDLLGRAKLKLGTVDDGLTFSSYLCSVNQSLWQHLHALAQRCGVDWYSDVEDAVHFKAYAAKTTHQAQYAQQLLQFSASPVQASIDGLEIHGTSPAGQGQSDEASSWLTKKVVKGSAGKSSGNVWRISDATARSQDQARQIAEHRFQAYAATLAGKAQVLGMAELALGDAIQFQQMPDASHNLSAKILSVSHKLNRYQGFVSEISWEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P6</accession>
    <name>A9B7P6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phage_base_V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1781"/>
    <dbReference type="EnsemblBacteria" id="ABX04424">
        <property type="protein sequence ID" value="ABX04424"/>
        <property type="gene ID" value="Haur_1781"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1781"/>
    <dbReference type="eggNOG" id="COG3501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085677_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1809-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="1">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="23976" checksum="C7E7D0E8AD792C82" modified="2008-01-15" version="1">MEELLQIIQRVAERSTQRIHTSELGVVTAVFSHADEGDNDNYQCSVQLRNYSLPDGSPFELRKVPVATPYLGLACIPNVGDLVVLSFIGGDINAPIIMGRVYNDEDRPPANNPKEFLLQHSIAEGGSLLLDSEGKIILTSKNGENTITLEDEKIAISNEKFSLVIDLAGEKISLSSNKDLSLIAETGKLTVQANAIELKSDSTLDLQASGAIKIKGSTIDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B809</accession>
    <name>A9B809_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine biosynthesis enzyme LysX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimK family. LysX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3306"/>
    <dbReference type="EnsemblBacteria" id="ABX05942">
        <property type="protein sequence ID" value="ABX05942"/>
        <property type="gene ID" value="Haur_3306"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3306"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054353_2_1_0"/>
    <dbReference type="OMA" id="YEHKVFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3343-MON"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011870">
        <property type="entry name" value="LysX_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02144">
        <property type="entry name" value="LysX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="98"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="31868" checksum="A86B3F8A64A6A178" modified="2008-01-15" version="1">MRVGMLCSRIRVEEKLLITEFERRNVQFERIDDDQTWFDLNALQANRQVREQFPDVIIERSLHHGRALYTLKTLNDAGIPTVNNYDVALTCGDKFLTTQALLCNGVPSPRCLLAYTQDSALEAIESLGYPVVLKPVIGSWGRLVSKINDREAAEAVLEHRDTLGNYQHAIFYIQEYVNKPGGRDIRAFVVGDECIAAIYRTSGHWITNTARGGQASNCPITPALADICIGAANAVGGGVVAIDVFETAEGRYLVNEVNYTMEFRNSISTTGVNIPERIVDYVLAQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B828</accession>
    <name>A9B828_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3325"/>
    <dbReference type="EnsemblBacteria" id="ABX05961">
        <property type="protein sequence ID" value="ABX05961"/>
        <property type="gene ID" value="Haur_3325"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3325"/>
    <dbReference type="eggNOG" id="ENOG50319N3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102452_0_0_0"/>
    <dbReference type="OMA" id="LSNIGVW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3362-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="25337" checksum="0487943CD6C6C713" modified="2008-01-15" version="1">MKPRFFAFGSQQLHSDAPQHHSLTRRMIGWIGLFVACLLLILYSFSQLDHIPLSTLTRDPADITGMPFYFGILSTLGVMLWSATTGVCGVGWLLLESSHQQRRFLGASALLSLILALDDAILLHERVFPKHLHIPENLVLAGYLGLGMAYLFYFLPRMLSTDYGLFMLAVGFMALSMIFDVIMPFHELATFTEDSLKFVGIVFWLSYFGRTVQTILAQAKLQRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B847</accession>
    <name>A9B847_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PT repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3344"/>
    <dbReference type="EnsemblBacteria" id="ABX05980">
        <property type="protein sequence ID" value="ABX05980"/>
        <property type="gene ID" value="Haur_3344"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3344"/>
    <dbReference type="eggNOG" id="COG5401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_499555_0_0_0"/>
    <dbReference type="OMA" id="EGPRNGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3381-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00909">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="3">
        <location>
            <begin position="281"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="3">
        <location>
            <begin position="413"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="514" mass="54475" checksum="7F91D2F66E1E7C3E" modified="2008-01-15" version="1">MTGEAHDIPVPQASFCLSSNHVRCPLYAGEDLPVAQVISTPTPVAVGGWRGWLAGLSTRDRRIYATLVGLLGLIIVAYAISGVVLFSNPDNPATPSATSQVLQPTSDSPTLTVSPSPNAFATAAVRQTQTAEVIAQTTTVTPSVSATSSASATTQVILASPTFVIVPPTEDVIVASATPSIPFATDLPTFEPTLSPIATTAVPTLEPTAEPTVEPTLEPTLEPTVEPTVEPTPEPIPEPTAQPTEETGGREVNQLTLFFADSTGQVLVPVSRQIAATRQSRTAAIQQLIQGARSDLRSLLPSDTQLLGLRLNNGIATANFNRIPTFGNSSLEDLGLRSIVLALTEQPEVKQVQIQVQGQNLGGLRYRPNVNPDNPQGLNGQFNTTSFLPLYFQQSSGRWVRVMRLVPSTKTEARATVNELIRGAGRYSHVVSSAIPSASQVRRLVIVDGVAQLDLSAEFSQTSNPQAAVDALVLALTSFSSVQQVQITVEGQSLSSIWGATFSNPFVRPQLNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B874</accession>
    <name>A9B874_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3791</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3791"/>
    <dbReference type="EnsemblBacteria" id="ABX06427">
        <property type="protein sequence ID" value="ABX06427"/>
        <property type="gene ID" value="Haur_3791"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3791"/>
    <dbReference type="eggNOG" id="COG0004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_1_0"/>
    <dbReference type="OMA" id="IFFMHAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3833-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RHESUSRHD"/>
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        <property type="entry name" value="amt"/>
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    </dbReference>
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        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
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    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="24"/>
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    <feature type="chain" id="PRO_5002735526" description="Ammonium transporter" evidence="9">
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            <begin position="25"/>
            <end position="468"/>
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            <begin position="40"/>
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        <location>
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            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU362002"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="468" mass="48723" checksum="3065DB2876DE43B6" modified="2008-01-15" version="1">MFRRRRWIVPAAVASLAIPTATFAQEAAPVATETITTQIDIIWLLIAAVLVFFMQAGFALVESGFTRSKNAANILMKNLMDFCVGTVLFFAIGFGLMYGASAGGFIGTDNFFLSDFSPATGSGKDWVGFFFQLVFAATAATIVSGAVAERFKFISYLIYSAVICGIVYPISGHWQWGGGWLFQLGFIDFAGSTIVHSVGGWAAVAGTILLGPRLGKFNKDGSSNVIPGHSLTLGVLGVFILWVGWFGFNPGSTLSGMNESIGYIAVTTNMAAAVGALSALITNWLITGHPDTAVASNGALAGLVAITAGCANVTPVGALFIGLLGGIIFVYGSIFLEKVLKLDDPVGAIPVHCFNGIFGTLAVGLFASPAVGGLTGMGDAAGLFYGGGLGLLGTQAIGVLAVGAWAFTTMFIVFYVLKKTLGIRVSEQEEIEGLDISEHDTVSYPEFGTPVAGVAGARSMMPELSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B881</accession>
    <name>A9B881_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06434.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX06434">
        <property type="protein sequence ID" value="ABX06434"/>
        <property type="gene ID" value="Haur_3798"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3798"/>
    <dbReference type="eggNOG" id="COG0318">
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP-bd_C_sf"/>
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        <property type="entry name" value="ANL_N_sf"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="499" mass="55705" checksum="109585C38982149B" modified="2008-01-15" version="1">MYIGDWLGKRELLTPERLALVDDRDGERYSYRQLNSRANRLAASLRQRFGVGKGDRVAILAKNQIGYLDALFATGKLGAILVPLNWRLTEHELIYMLKDSASSILLYDSQFAPLLPTLRSQTPIKQCVQFGPEYDQLLTQASDLPISESVDLDDPHLILYTSGTTGAPKGAVLSHRVLVWNSLNTNVGWDLHADDVSIIHTPLFHTGGLNVLTLPILHAGGTMVLMQEWNPERCLQLIEQEHVTIFFAVPTMFEMLLQAPNFVQTNLSSLRFCIAGGSPCPIPLIEAYQQRNIPFRQGYGLTEVSVNCFTLNPEDAIRKAGSVGKPIFHLDARIVDEAGRDVPTNSIGELILYGPTVCNGYWRNPVATAQALQKGWFYTGDLARVDAEGYFYIVDRKKDMYISGGENVYPAEVENVLYQHPAVQECAVIGIPDSRWGEVGRALVVLRPSTQLDEPTLIAFCRERLASYKTPKSIYFLPELPHNASGKVVKPELRKLFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A1</accession>
    <name>A9B8A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_3818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3818"/>
    <dbReference type="EnsemblBacteria" id="ABX06454">
        <property type="protein sequence ID" value="ABX06454"/>
        <property type="gene ID" value="Haur_3818"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3818"/>
    <dbReference type="eggNOG" id="COG1287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_427459_0_0_0"/>
    <dbReference type="OMA" id="FTEGLPC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3860-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
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    </feature>
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        </location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="558"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="640" mass="68796" checksum="E892A148EBA084EF" modified="2008-01-15" version="1">MALGRYARPLLLSSVVAGLLLWLGWQRLVPFNLAIGGDLVIGESGEQFALMYDQPYLEHVHAPEPATVDLTTTETYRWTQPESAITVPYLNGSAHIVRLSLAPPSVPQTPFLLQANGAAVRTDLPPGQRTLHLFAPASSDGSLTLELQAPTYNASPDPRLLGVVLYRMQAQPLSHDWFLPWAAWIDLLLVVIVVGLGAALAGLAPLTAAGAILVTSSGLSVLLATVRTVITLDTGQLRTISLACLLVAWLGRWLAERRQNPEIALVAGMTALGLALRLIGIRHPQTNFSDLLLNVNNLASVGSGDLLFTEGLPCAAGAGRSPYPPGTYLITQPLSLLLPASMNRGILIQIVGAVADALVIPLLWWLIDRTRDARTPARAALWAASLYLAPLAMLRAMVIGEWSNVLGQAIAMPILAWLGLWLASNQPRAWQPALIAGLTIAALQHSGTMLSLGLWGVALAGFLVWQKQWQVLGRLVVVGTSAVVLAVGLYYSNFLGDPTLANNGVICPAPRPFDQKLWGVVWNDLIALDGRVPAWFWLVGLGGAFSLRQGLSRLATPIWAWLATFVLSLSSLLWSEQTVRWWLFILPALALSGGVGLATLAQRGRFGRVAAIAASLFIIAASLALWTRFIIEYRTGAFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8C6</accession>
    <name>A9B8C6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3843"/>
    <dbReference type="EnsemblBacteria" id="ABX06479">
        <property type="protein sequence ID" value="ABX06479"/>
        <property type="gene ID" value="Haur_3843"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3843"/>
    <dbReference type="eggNOG" id="COG4262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008530_1_0_0"/>
    <dbReference type="OMA" id="WQGGKRA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3886-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="544" mass="59332" checksum="C98485A6D7E6C9F1" modified="2008-01-15" version="1">MLLVFGAGICTLGIEMTASRLLAPYFGTSQLIWANVIGLTLLYLTIGYTLGGRWADRRPELGLLCTIILVGAITAAVIPWISRPILKWSLEAFATRSAGSFIGSLLGVLALFSVPITLLGMVSPFAVRLAIRDAADAGKAAGNLSAISTLGSILGTFLPVLFLIPTVGTNMTIYIFAMGLLVLILPGFWLERRKLLPVALVALIVVVALAFWPQSEPIKVADCRGCSLITEDDSAYNYIQIVERGSDANKMIGLVLNEGQAIHSIYYPKFEQTNNASDLLTNGPWDFYNIAPYFYPNRSMESVNSMAMVGSAAGSVPKQFLAIYGKDSVIDGIEIDPRIVELGREYFAMHDVQYYQARGETPQFPNFNTYVADGRIFFAGNDNKYDIIGMDAYKQPYIPFHLTTREFFETVRDHLAPNGVAVVNAGKPNTAAGGDYRLVNVLASTMSSVFAHVYMIDVPNNFNTMLIGIPGDVGDGVANFEANLATIQDPTLRYVMEQALASNSSKKPIRRWDGVGENRVFTDDLAPVESVIDRIILGQVDEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L5</accession>
    <name>A9B8L5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07679">
        <property type="protein sequence ID" value="ABX07679"/>
        <property type="gene ID" value="Haur_5051"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5051"/>
    <dbReference type="HOGENOM" id="CLU_1956591_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5113-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14418" checksum="3BBCDF2418368ECA" modified="2008-01-15" version="1">MTLNNDDRDSLVSRLRDLADEELLGVLQRVFADRTLLGTEVPIVESHFFLGNATRLYENTPDGGQAWEPWEIHAIAYPDLSAYDADPDWFGFDYGFSEWAICSTCGIELRCNVKYGICPVCSTKAYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T1</accession>
    <name>A9B8T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07745">
        <property type="protein sequence ID" value="ABX07745"/>
        <property type="gene ID" value="Haur_5117"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5117"/>
    <dbReference type="HOGENOM" id="CLU_1105966_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5179-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="28038" checksum="A430AD82C05D0A0E" modified="2008-01-15" version="1">MTPCLPPHDPILVASLHAGLTALGPLDRATIGRIWFPTKGDQAIRRILRPLVQQKLLHATVLSNGRQRIAMRYHATAVPATDLVILPPIRMAAALLETAQRLPDLVSVQTTVLDLYRGGGRIVGLRTRTTPSRRPSPPILRWNTAAPRDREQDTWYLLVPDHEQVSRDQHAMRARWYRDLATTRGFPMPIPLIVTSPARRAIVDYAWTPHWPQLVIGYASPDGPWTDVAWHPIVDGTALPPPVPITQLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8V3</accession>
    <name>A9B8V3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07767">
        <property type="protein sequence ID" value="ABX07767"/>
        <property type="gene ID" value="Haur_5139"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5139"/>
    <dbReference type="HOGENOM" id="CLU_817945_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5201-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="39432" checksum="9996D25ADBF25AA5" modified="2008-01-15" version="1">MNEIISFDLMYEQISGAGEDAFPILMVDEYPNCGAIAVFDGLGGAGGTIYTVNEEEHTAAYIASRMVRNIVYDHLQSLLNKLINEESFSCSLIASELKDIIITRMRYAIEDKNINIPSSKIKSALVQVLPTTMAMLLFTKYINNQTITYNYYSIWAGDSRNYILTSDYGLQQVTKDDISQDKDAFELLKQDCPLSNNIKFSEDFYINCKKITSDTPMILISATDGCFGYLPTPLHFEYFILDSLFKSNNVLEWRDLLNDIIKLYAGDDFSLSLVVIEWNDLDILKNNFKKRYEYCKVRVKGIDIVKRNIEVLSKHELFYTNRLWELYRSDYEHFIRDLGGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z1</accession>
    <name>A9B8Z1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07805">
        <property type="protein sequence ID" value="ABX07805"/>
        <property type="gene ID" value="Haur_5178"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5178"/>
    <dbReference type="HOGENOM" id="CLU_2023532_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5240-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="13247" checksum="26DC7A7EA7DCC1A0" modified="2008-01-15" version="1">MRSPDPTTGEPIRLYGHDRCPAVPPVRGLLNRASIPYVYINIHHDPAAAAVVQQINDGNESVPTLVFPDASTLTEPTTTQLVTRLAQVGYAVPWHAQLIGHSWKLLIVAGILLAIVRGLGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B952</accession>
    <name>A9B952_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5239"/>
    <dbReference type="EnsemblBacteria" id="ABX07866">
        <property type="protein sequence ID" value="ABX07866"/>
        <property type="gene ID" value="Haur_5239"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5239"/>
    <dbReference type="HOGENOM" id="CLU_1903821_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5301-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14318" checksum="D1914D4861EC5E80" modified="2008-01-15" version="1">MQRWCLVLMGLVVASVLGGCGEDASSKSSVDVITTWAEAVVADDWSTATAMIGWEPERWEKVLRGDDGTDDYTAYALVGDPVVLTASTTAKIQWTRAGDPKPQCMTVEVGTSNRITVNGWSLCPGESLNRHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK7</accession>
    <name>A9AUK7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1891"/>
    <dbReference type="EnsemblBacteria" id="ABX04534">
        <property type="protein sequence ID" value="ABX04534"/>
        <property type="gene ID" value="Haur_1891"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1891"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="GETVFFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1920-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="35045" checksum="55F16327FF0F38F0" modified="2008-01-15" version="1">MSPIVQVEHLGKQYNAPNGPMAVKDVSFEIQKGEIFSLLGPNGAGKTTTISMLSCLLQPTSGTILIDGHSVTKEPKQVKQVIGVVPQDIALYPTMTAQENLLFWGKMYGLSGKHLQDRISKVLTIADLADRANDKVETFSGGMKRRINIAVGLLHDPKVVYFDEPTVGIDPQSRRRILDSIKQLNTHGISVLYTTHYMEEAQELSHKIGIIDHGELIAVGSQEQLTQLVGQHDLVQFEIDPTAANLDATLSALKVINDVDQVTSSPEENLITVQTRNTNAILPQLISQMTETGTPIKSLTIKAPNLESVFLHLTGRALRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM4</accession>
    <name>A9AUM4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1908"/>
    <dbReference type="EnsemblBacteria" id="ABX04551">
        <property type="protein sequence ID" value="ABX04551"/>
        <property type="gene ID" value="Haur_1908"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1908"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520641_0_0_0"/>
    <dbReference type="OMA" id="EAYQFQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1937-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="213"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="269"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="487" mass="53812" checksum="581CC62506D1BBF7" modified="2008-01-15" version="1">MNITSREWAMIEDFSRRITTEAPQSLVALAQSLSAAFQVDVTIWSRTASGEYHCVTPSAGQPEGLMMSAEQALNVEKATLIFVYEAFYAAKFNPAHNFSPAQVMIIQALLEGWIGRLRTSYVEPHEHENLGDLHQSLLQSIIDVLPEGVVVGLAPDGQLILANRQAEQLWQHPLHSVPVEGYSHFGLYKPDGTRLPAGDSGIARVLRTGEPFLKHDLILRRPDGSEIPILANTSPIHDNRGNLIGAVAVFQDITGWKLQESDRDNAIATIVHDLKNPLTTIRGSADLLLRRAKTENRSERELNRLQSIIAQSDRMRDYLSLLVDVARINAGETLISPCLLDFGELVGQLIATINGGLANPRINVELLARPLVRVDPIWMERVIWNLLDNALKYSADDTNIDVRLELEHDQVLLSIRDAGLGIDPQDLERIFERFTRGRHTQRVGGTGLGLYTVRAVVRAHGGSIVVESEGLGRGSCLTVSLPVESNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN0</accession>
    <name>A9AUN0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1914"/>
    <dbReference type="EnsemblBacteria" id="ABX04557">
        <property type="protein sequence ID" value="ABX04557"/>
        <property type="gene ID" value="Haur_1914"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1914"/>
    <dbReference type="HOGENOM" id="CLU_1693093_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1943-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735220" evidence="1">
        <location>
            <begin position="23"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="16427" checksum="7CCB62ECF08B7257" modified="2008-01-15" version="1">MSRYWLAISLILTIGLPTTNTAAFTQPIIAFEQGNCPPGETEVIIWPTLQTISSTTPHAGDPIVIQGSGGFIQCSGGLYNESARSFVVTLDAQPIGQLGCYANYCQTTLTIPLTTSSGVHLIATEGGSQMSIIVQPQRATQGIQFLPMLIQGAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP7</accession>
    <name>A9AUP7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrin alpha beta-propellor repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1931"/>
    <dbReference type="EnsemblBacteria" id="ABX04574">
        <property type="protein sequence ID" value="ABX04574"/>
        <property type="gene ID" value="Haur_1931"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1931"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025051_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1960-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="684" mass="70320" checksum="3418A4672F6630C8" modified="2008-01-15" version="1">MSTPKPIVYARMLLGLLLISISFGLGLPRIAAQTPRDEATERLNSADWAAIQGLLAPTTAISGSKFQAGYLKAAQVSAGDSFGASVAISGDTVVVGVPAESSSLAGVQNSATPTINALAAQAGAAYVFVRGSAGWQQQAYLKASEVSANDQFGWSVAISGDTIVVGSPRESSSTVGVQNSATPTVNNDLGGAGAAYVFVRTGSTWSQQAYFKASQVTSGDWFGWSVGLASNTIVVGAYGEDSNIVGVQNSATPTVNEAATAAGAAYIFVRTGSTWSQQAYLKAAQINTDDVFGWSVAVAGDTVIVGAPGEDTSIAGVQHSATPTVDETALAAGAVFVFTRSGSSWSPQVFVKASQVTPGDQFGYNLAIAGNTIVVGAPYEDSSTSGVQHGASPSVDELASFAGAAFVYTQNAGVWSQQAYLKASNVADGDRFGMSVAIDANTIVVGAPEEDSGIAGVQNSALPNADESAIQAGAAYVYARNATTWSQQSYLKASQVSTGDYFGRGVGVAGDMLVIGIPLEDSARSGIQNSATPSVDELAADSGAALIIDTTYRSYSPLVQRMTLLALLTINSTAIPIRAVTQQGEVFASFTATLPTTIPAGGHIYLSASPSSLQPTLVDDRIIIRDGANIIFQHTYDLESNGELVEIPWEVINAASGHSLTITFVDVSAGLVGATPIYLIWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV9</accession>
    <name>A9AUV9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3913"/>
    <dbReference type="EnsemblBacteria" id="ABX06547">
        <property type="protein sequence ID" value="ABX06547"/>
        <property type="gene ID" value="Haur_3913"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3913"/>
    <dbReference type="HOGENOM" id="CLU_942578_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3955-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="33432" checksum="94920F97525D2D9C" modified="2008-01-15" version="1">MPTIETTQATSILGFIPWGEAGLKPIDIQTSLPNQPLGRMTPEIVLDTQQQPWFWLDGRIINVDDQRYWEINQSVKANATAVMPTPQGFVVAVASPRTVGIQLLDLNGKLLWQHDRPFELPDELDQRQLLLQDADRVWLYAGNRAGWQLWEINLQTGELSPQFAQNTPAPSQIWLYDGIVMWWSYQASSQTRQWHRHNLATQTTSTVEQSPLNRWFANIKSATPTGGALLVTTNEIIWMDADGQEQNRLTSNDLLPPSWQPATYSLIPSRAVVNAQGMMLWLGFDQQGVYLLQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY5</accession>
    <name>A9AUY5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1094</name>
        <name evidence="3" type="ordered locus">Haur_3939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1094"/>
    <dbReference type="EnsemblBacteria" id="ABX03742">
        <property type="protein sequence ID" value="ABX03742"/>
        <property type="gene ID" value="Haur_1094"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06573">
        <property type="protein sequence ID" value="ABX06573"/>
        <property type="gene ID" value="Haur_3939"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1094"/>
    <dbReference type="KEGG" id="hau:Haur_3939"/>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686571_0_0_0"/>
    <dbReference type="OMA" id="AAHGWGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1114-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="133"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="44541" checksum="A8B9A09F97043C55" modified="2008-01-15" version="1">MVQPYPLTNRGRMPSIPALAQWINTILLTAVPTLSPWTARRLTDWLLSILLMPSITTRVVAWGCALGLSTAARAASHERRLRRTYRDSQLSWSLHRAILTTTLRFAPAEAVTVIIDETTHTDHWTLLTAALWYHGRAIPLAWVLHPGNTRRTTAFWMDTATLLDRVQQVLPATTDVVVVADRAFGCPAFTDQVAAHGWGWVVRVQGHTRMLLRGHTEVPIRTLVGRGQRVVRRGQAFKKAGWRTVTVVAEWTAVAQEPLLLVSTLAGIGAIRHAYGRRSAIEALFRDWKTGGWQWEASQSRSQTTQEALVLGMAIATVLVLLVGTAEAQAVLAERGDRPSPRRPWAARESLFRLGRYGVLRWLWTGTQPALGARLSLAETALHERWATTVTRGGRLGTAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM1</accession>
    <name>A9AVM1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3989"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06621">
        <property type="protein sequence ID" value="ABX06621"/>
        <property type="gene ID" value="Haur_3989"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3989"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_0"/>
    <dbReference type="OMA" id="QTFARRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4031-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="27560" checksum="ED992E1ECB374CB7" modified="2008-01-15" version="1">MAHTDYSVDIVIPVLNEEQQLEQSVVALRDFLQASCPYRWRIVVADNGSTDRTPQICHDLRSRFPGEVDFERLEQRGRGRALRTAWLKSSADILCYMDVDLSTNLRALPPLLAALIHSDYSLGTGSRLMHGAIVTRQWKREMISRAYNLLIRVLFWHRFRDAQCGFKAITRQAAQELIPMVRDNEWFFDTELLLKAERRGYRIFEVPVEWIEDLGTTVKIVKTAWQDIKGLVRVRLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS9</accession>
    <name>A9AVS9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein Haur_4047</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06679">
        <property type="protein sequence ID" value="ABX06679"/>
        <property type="gene ID" value="Haur_4047"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4047"/>
    <dbReference type="eggNOG" id="COG1666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099839_0_0_0"/>
    <dbReference type="OMA" id="SDFDRQE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4090-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18604" checksum="223A291B6C0E07DD" modified="2008-01-15" version="1">MAEFSFDVVSDFDRQELINAVDQTKRDVGTRYDLKDTNTDITLGEKDITIVTSSELALNAVRDLLETKALRRNLSIKMFDFGEPEEIGGMKIRQVITLRKGIADDIAKKIQKLIKAEVPKAQARIQGDSLRVSSKSKDELQAVMSLLRERGDDFPLPLQFNNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY8</accession>
    <name>A9AVY8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0578"/>
    <dbReference type="EnsemblBacteria" id="ABX03226">
        <property type="protein sequence ID" value="ABX03226"/>
        <property type="gene ID" value="Haur_0578"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0578"/>
    <dbReference type="eggNOG" id="COG1769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044328_0_0_0"/>
    <dbReference type="OMA" id="LELHAEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-587-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019117">
        <property type="entry name" value="CRISPR-assoc_protein_Cmr3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09700">
        <property type="entry name" value="Cas_Cmr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="396" mass="43754" checksum="25BF40F3E212117B" modified="2008-01-15" version="1">MTLDLWLIQPFNSLVIADGRPFENQPGARAKSLSFPPPSVTVGGFRARAGVKANYNFSAKLSDPEYTNLLAMQVRGPILLKETVDLLIPFVAIPADALIRQDGANVTCYRLQPLDPRYFPTEQTDLVLGQQPDQPRFSLVGSQQHTKGKAPANLPRFWNWERLFLPWLINPPIQPFDLEQQRAAGQMLDLEGDTRTHVGIKPSTQIAEDGQLFQTQGLSFQSLEAGYGLGLWSSTPIDPAVASLGAERRLVEWYRVPSGTAAGIETIEPSILAAIVQTKHCRIILLTPAIWDAGFYPKHLPTFGLPMTATIKAVVNPRPEYVSGWDLRLQRPKATRRLAAAGTVLFVELTGSDAEIEQWARQLWFSNISSSEQAAKDGFGLAVLGIWNDGYLQELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW70</accession>
    <name>A9AW70_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2080"/>
    <dbReference type="EnsemblBacteria" id="ABX04720">
        <property type="protein sequence ID" value="ABX04720"/>
        <property type="gene ID" value="Haur_2080"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2080"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1127855_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2108-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="26550" checksum="56D7257B35408FC1" modified="2008-01-15" version="1">MDDLDLHLALEALRTNPAAHAYHERITRGMQAIEQESLTPFEREVLHRLLARFPISPPADPVAALIAAFQDKLPTYDPAAVAIAIQHALAQRPATLNGAPVTITMNGDTHAHQANLAIGNQVGGNLVQITVTIPIPDARFDALLATALKTHEHEKTQARIRHAAQQIESDRLLNLRLEGFVGRVAELAAIRKQIAAMRPTGGYVLIKAAAGEGKSSSIAKLIQQAGIAQTPHHFIALTTDRAYQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWI9</accession>
    <name>A9AWI9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transferase hexapeptide repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4116"/>
    <dbReference type="EnsemblBacteria" id="ABX06748">
        <property type="protein sequence ID" value="ABX06748"/>
        <property type="gene ID" value="Haur_4116"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4116"/>
    <dbReference type="eggNOG" id="COG1207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_587770_0_0_0"/>
    <dbReference type="OMA" id="KNCSIDP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4162-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="48166" checksum="1B09F95E6009CBEF" modified="2008-01-15" version="1">MKRIVLRDPTLIAPFGEPARDLRILNKPLWLLHRDLLARHCQSVAEVDDWSEISPSSDELLVHKDNLYFNRDFIETFIAEARATGQPCQVAFAADDAMITAHALRLQEGIRKHGNHFIADLYYFPRGVVPNPQPLVIDTNAMEMGYYHIPSYMAPNQGDLVFQVPIRAFCSIESWVHIFMTNSPLGVFAWGRKLEQEVAASWRLKLKIGFRSFIERKHFLSSSPVVKIGKNCSIDPSAIIQGPTEIGNNVNIGAGVVITNSLIGNNVTIMQGSQVMLSVVSDRCYLPFRAALFMTVLMENSMVAQNTCLQLCVVGRNTFIGAGNTCTDFDLLGKPIKTLHRGRLEEVGLPVIGSAIGHNCKIGSGFVIYPARNIESGTVLIYGDDHSVIPKNVSSGIYTRPPVFYPDRDPRVQRVPVNDRVADEYPAEQFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL9</accession>
    <name>A9AWL9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4146</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4146"/>
    <dbReference type="EnsemblBacteria" id="ABX06778">
        <property type="protein sequence ID" value="ABX06778"/>
        <property type="gene ID" value="Haur_4146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4146"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_2_1_0"/>
    <dbReference type="OMA" id="HADHEMN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4192-MON"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="41277" checksum="4FEC5169DAA8090E" modified="2008-01-15" version="1">MATETQVHVGLEGIVAAATRLSSVDGQAGELIIAGFPLERLAPFATFEETIFLLWNDHLPSQSELAELRQSLASQRQLPALTLEVAQQLGREQADPMDALRAATATLNPLADEKATAQRIVAALPTIVAAYWRARNQAEFIEPRSDLSHAANYLWMLTGKEPSAEKVRALETYLNTVVDHGLNASTFTTRVIISTESDLVSAITGAIGALKGPLHGGAPGPALDMVFEIGTADRAEEVLRAKLARGERLMGFGHRVYKVRDPRAEVLAGAADQLFANDGNRELYELVRHVEQTAIRLLEEHKPGRKLQTNVEFYTALLLHGIDFETDLFTPTFTISRAVGWIAHAFEQRAVGRIIRPQSIYTGERNRTWVEVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN6</accession>
    <name>A9AWN6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4163"/>
    <dbReference type="EnsemblBacteria" id="ABX06795">
        <property type="protein sequence ID" value="ABX06795"/>
        <property type="gene ID" value="Haur_4163"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4163"/>
    <dbReference type="HOGENOM" id="CLU_1336002_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4209-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="22013" checksum="6447128621EC0ACA" modified="2008-01-15" version="1">MCSRSSAVIPIRLWWFPKPKPSILIANQNHMPNWSLTQLRQLLLIGLLAPLLTGCLLMAGRNEQATITAELGSQNVEFVSSDTNGEAVLQALDIGTLPMLLDVTFNAQVASGELVIEVLSGEQANVAFTVVASAEGSSQRGIVMSNDVGDLQYRVRSTNARNGIYRISYQPPPTPTPTLTPSPTWTLTPSTTPTVEPTAEVTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX60</accession>
    <name>A9AX60_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2228"/>
    <dbReference type="EnsemblBacteria" id="ABX04868">
        <property type="protein sequence ID" value="ABX04868"/>
        <property type="gene ID" value="Haur_2228"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2228"/>
    <dbReference type="eggNOG" id="ENOG502Z9DU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_280448_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2256-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017589">
        <property type="entry name" value="CRISPR-assoc_prot_Csc3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03174">
        <property type="entry name" value="cas_Csc3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="981" mass="111226" checksum="7A0E80C20842DED9" modified="2008-01-15" version="1">MDAESTTYAEGDPPTEDSSQLDPEFLDLLLGKAPNEEEIFERYRKHILNDGLLCYKKTIQFSMTEGGKAGESLYSHILNGILVLQDLRSIVHLTDEETKVLFTAFTIHDINKVQPTEQRQSYLDLTKPNIVANEMSKVKLDVFFDGYEPYLNDIISLMQRHSGHNWTGVQALNLKNQPKFKLPMERLDQLVLLMRAADGIDLSHTLEEQRHKEQFLHSINTFSPQQYAFWRHRVAEQRGNLTNIIHNAVAAELSERFGLVPLLYYPDGVAYLKLKATSLQPEPNLYPAIAARVANTINSMTSAGFREFIRAINMGITVDRKCLELNLPFAQILAAIDTIIQRRTVKDDKLQALSQASIKRTRDLLAKRQAKTANSNDQRAINQAIEVMLERGPVPQTNSQMKVGELIRTYYIFLIEHFEQAIPDAWQHIYQLLELPAERWAIYDGFDARMDRAYAIATEISLTADQIYQRIEADGGSLINTQTTLDPRLPTIEAYLKHVLVFDGQARAAGDFASSLPNYVRQNSKQCVQCSLPMPTQKWGSANVRSDIKIQMFSNRLTGGPGEPVKHICEVCLIQYLVEKLNYREVSGERTIYLHMFPYSFLPAPLLEGLRATFRSLLSEDSITGAVRLADVSNSMLQRTPTLRFTTRTKANKPQPYGLYSPRYSETLGGLITLPLNPAGDTDTERFLFALQHALLLHQHFGCKVLLSNAAVPPLDKTAFSDLYIDLTPLQARGFVRQNDYEHFKQGTKESGSLAKLWDQLDWLYQIREVVAMANADPVVDFIGAMADHPLRIFYLAEKYAEAKAGHQASSWLIHTMFNPVQQLALSMGDRSMEQLDFCLNRLAEIARHGNLRGSSWKKSSMITALDEVLRKVNLQSEELTPAVLQAAAIEDMFQHIQRTRNLRGFSGGKKLRAACEEFVQVFFNDIYYGVYAGKPARLLNHEKVLRSAYHFYVQQHFRAKPLSPEEAQAEGLNDDGDVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXF3</accession>
    <name>A9AXF3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4241"/>
    <dbReference type="EnsemblBacteria" id="ABX06873">
        <property type="protein sequence ID" value="ABX06873"/>
        <property type="gene ID" value="Haur_4241"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4241"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_0"/>
    <dbReference type="OMA" id="SCDMVVC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4288-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="27809" checksum="8E9A4FF7371FA275" modified="2008-01-15" version="1">MTDTLLISKADNVTTLTINRPAVRNAVDQPTMDALRAEIEACEHDGTRCIVIAGAGGAFSSGADIMAALQSGGTANDVYRVLTESYGPTLLAIRQSSWPVIAAVDGVAAGIGSDLALACDLRLVSSRGRFSEIFIKVGLIPDGGGTYSLPRLIGLGRAMELMFTGAMVEAERALAWGMANAVFDEANFANEVQAYAATIAAQAPLALTRGKRAMLAAQNDQSFADALRREAEYQREIFNSEDGFEGFQAFLQKRPPVWKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXG3</accession>
    <name>A9AXG3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4251"/>
    <dbReference type="EnsemblBacteria" id="ABX06883">
        <property type="protein sequence ID" value="ABX06883"/>
        <property type="gene ID" value="Haur_4251"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4251"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972457_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4298-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="41"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="180"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="29946" checksum="3E5B215BA342E259" modified="2008-01-15" version="1">MTKNIAVSLLFTLATVALLGFIWFGQTNDRLAATNLRQDALQLEFGQRNYEQYCATCHGLAGEGQGPGNKAAPKLSDLQGRLGPGTEAFTRENGIQKKYGSLRNYVEAIIAYGKTGTAMPAWKLQGMRDDQIKAIASYVMSMQGGAVAPSALDSAKSWSATTEAGLPPTATPNEPPLDDPLAEAGKQTFNTYCISCHSKTDASGAGPGLAGLFGESGTKAFGTTLPNGNPVNDANVLDWIKNGGGGPGVGPDPQDGASYGVMPAQGQILSEDKILEVIAYLKTLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH4</accession>
    <name>A9AXH4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06894">
        <property type="protein sequence ID" value="ABX06894"/>
        <property type="gene ID" value="Haur_4262"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4262"/>
    <dbReference type="HOGENOM" id="CLU_1419744_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4309-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21589" checksum="6E464188940BBDBB" modified="2008-01-15" version="1">MNYYQDVFPWEVVVVSSVILASMALFSTVRWIFRPQPKVFPGKRIVLFVICLGLIFYAFRFVPNFRDKFELGLSTNRAATSDNPILPELMTPRFTQDQNTVYQAGIRTIQAQRGWTITNRSDSQKALKVDIDVMLGIFTDELTIAFIDEGGQTRVDIQSASKVGGADLGANRRHIRQLVRALEEDLGTPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXM7</accession>
    <name>A9AXM7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0793"/>
    <dbReference type="EnsemblBacteria" id="ABX03441">
        <property type="protein sequence ID" value="ABX03441"/>
        <property type="gene ID" value="Haur_0793"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0793"/>
    <dbReference type="HOGENOM" id="CLU_1480114_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-805-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="20913" checksum="5A3AD2546A1D8CFC" modified="2008-01-15" version="1">MRRGVFMQRRMLLHHPARDHWLVIAATDSQPCTAVSEPLHPDQLGFPLATFPLHPLEQHTEPFDLSEYVCIRTNREESTANEIADMLNSAIMMELDQTAVTLGFSEGDQFFKQQPQRYVQEIAHWLNTPPSNLNLEYLLIDQTETQALFQIRDPTTRQVWRLTRTMPGVDAKPDGVGWGWSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP0</accession>
    <name>A9AXP0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0806</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0806"/>
    <dbReference type="EnsemblBacteria" id="ABX03454">
        <property type="protein sequence ID" value="ABX03454"/>
        <property type="gene ID" value="Haur_0806"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0806"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_532000_0_0_0"/>
    <dbReference type="OMA" id="DCDEAAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-819-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="63"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="483" mass="53947" checksum="1FB592AF9CBCF59F" modified="2008-01-15" version="1">MLRRFRRRRLALWAVIGAVCGLIVILRMPLHQLPLERDEAAYAVIARDWADGAIPYRDRFDHKPPFVYAAYAPPVLLGTEPIQTIRVWATLWLEATTLVMWRAGRRLWRSEAAGVLTAILVASWNSAVFLQGVTFNSEAIMLLPSCLALLFGLKALDSQQKAWWMLAGVAAALALLSKPVALLILPALIITTIAFKGDVNERLGRAILVIDGLALVLIPTLLYFALAGGWSQFVEALWTYNTAYLDQTDATISQLWPIWRSLLLLLVAGIVGATMAWRRRRYGPSLTLAGLWSIGLIASAFVSLRAYPHYYQALVPALAVFAGGLAKVRLGFLQQYKDFSIVVIAFLLAIQPLASLWPLYNKTPEAQIEQLYGVDGREFFALAPKVVEWIDSNVGQQASVWVWAAEPEIYLYGDYAVPSRFPYDYPLAILPNALDQTLQQLRSQPPKVIVTYGAVRPIGFDAMLQVAPYRLRVHLAGYDIWVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP2</accession>
    <name>A9AXP2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoenolpyruvate carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0808</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0808"/>
    <dbReference type="EnsemblBacteria" id="ABX03456">
        <property type="protein sequence ID" value="ABX03456"/>
        <property type="gene ID" value="Haur_0808"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0808"/>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006557_2_0_0"/>
    <dbReference type="OMA" id="GPTHRFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-821-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="908" mass="101411" checksum="84BC51FEEE28B1FF" modified="2008-01-15" version="1">MANLPSYDFADLIKADHDAEFVLTCFAEVLQELGEAELAAYLGLPTTASINQTITPERAIQAASLSFQLLNMVEENAAAQQRRIREAAEGFNAEVGLWGNTLQSLSQAGFSAEQIGAALGQIYVEPVLTAHPTEAKRATMLEHYRRLYLLLVKRENPIWTPLEQQALRDEIKVELERLWRTGEIFLEKPSVADELRNILHYLRHVFPASLVTLDLRLQQAWQLQGFDRRLLPTTEQLPHVQFGTWVGGDRDGHPLVTAAVTRFALQELRRNALEVLHEQLVQLVIKLSLSDRLQPPHAALLEALDASAAALGQRGQMALARNPEEPWRQWINLIIARLPESGQLRQPWQYRSSSETVADLQFLAEQLHAVGAQRLVLNDLQPVIRSVQTLGFHSAVLDIRQNSKFHDLAVEQLLQAAGFSDYQFSSWPEEQRLELLNRELQSARPFAHPSLELGNEASAVRDCYRVLADEIAQHGTAGLGSLIISMTRSLSDLLVVYLLAREASLLYVTEAGLACVLPVVPLFETIEDLEISPGILDAFLAHPVSQASRALRQTSVQQVMVGYSDSNKDGGILASLWSLYRSQGTLAAVGAKHHVRVRFFHGRGGTISRGAGPTHRFLNALPAAALAGDLRMTEQGETIAQKYANHITAVYNLELMVAGVTEATLLGSQRDQTPHSLAPIMDVLTAYSRQRYETLIQTPGFIQFFGQATPIDVIEQGKIGSRPARRTGQRTLGDLRAIPWVFSWSQARFFLSGWYGVGSSLAWLAEQHPEQFDQLKQAAFEWYPLKYLLTNVSTSMLSADLATMQAYSQLVEDPSVRQPIMAAIEAEFKQTQQQLELIFGGSLAERRPRIYRMLQGRQSRLSQLHQQQINLLHTWRSLPSEQIPERERLLTQLLLTVNAIASGLRTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXZ3</accession>
    <name>A9AXZ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04959">
        <property type="protein sequence ID" value="ABX04959"/>
        <property type="gene ID" value="Haur_2319"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2319"/>
    <dbReference type="eggNOG" id="COG5562">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133369_0_0_0"/>
    <dbReference type="OMA" id="YAIDFRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2347-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009833">
        <property type="entry name" value="DUF1398"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036696">
        <property type="entry name" value="YdfO-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07166">
        <property type="entry name" value="DUF1398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160419">
        <property type="entry name" value="SSF160419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14711" checksum="CB9298D30816D804" modified="2008-01-15" version="1">MSTFDQTLLQACAESTLNGTLPFPEVIQRLSPSVEQYHVDLIRLEMTYYGHQGQSFVYPLNLNKLPAIASQLDLVAFQTALKASQRGEISYPTFLQQSMAAGVSSYLVFLSGRLAIYVGRNGAYSVEPFPTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY04</accession>
    <name>A9AY04_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2330"/>
    <dbReference type="EnsemblBacteria" id="ABX04970">
        <property type="protein sequence ID" value="ABX04970"/>
        <property type="gene ID" value="Haur_2330"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2330"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331147_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2358-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="865" mass="91332" checksum="93F044ECE1B9C028" modified="2008-01-15" version="1">MQPSFVQQRFRSVVSALIILTFGLGSFSWLLQSAFANTIDATPYLNPLAPDFGIQAAIDAAAAQGGGTVRLPAGSFTLETYLDLKTGVTLQGVGAETILKAGRNEQRVFVTQTGSNLSTIKVASVTPFRVGMIVYVWRSTELRFLPGSYEIMSINSTNQTITLDRAVNYPLTANVSQVSYGLYTKLTGAATQGTNVISVADTSVFNPGEGIIIKGTEGTGIGNWGVEQNMVDSINTSNNTLTLKKPLTLSVPNNSVVSHAYSAIFALGTNFNNRLQNMGVRDLTIEGWNTNQKPAFYEFYIGAINFVYCRFVTIDNITVRYWHSDGVSLQSCDQSTVSNSLATANRGHGFHPGTASRDIEFFKIQGIGNLGYAARGTAGDGLYYCWANQRVNIRQSVFRNNAGSGVGDLGGGDTDNSSRDTDNIIEDSIMEGNFRAGIEVNGGGNTANNIIRRNVIRNNNTGNQDYAGINLLSKRGPVQRYIIQDNIVENTAGSNQLFGIREVNLAVPPTTPVDYLTDFNTITNNTIYNHPSNNLVVIGPNTVATGNIFTAPGAVITPTPTNIQPTATATIAPTNTPTPTGSYVPRLIMYNADTDQVMYDPIPNGVTINYATLGTRNISIVAPTAPSSGIGSVRFWVDSVVYRTESGRPYSIAGDQTNGTDFLPMNPALAHGTHVIKAATYTGSGGTGTQGTPYQIVINIVDSNATATPIPTNTNTPVPTVPTATATATNTPTNTPTNTATNTPTATAIATATNTPTEIATPTATVTEVATATPTEIATITATATDVATVTATEIATATATATITATLTNTPTNTPTNTATATLTETPTATLEPSVTPSNTPTATTTVTTPVPSTHHVYAPWVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY26</accession>
    <name>A9AY26_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4276"/>
    <dbReference type="EnsemblBacteria" id="ABX06908">
        <property type="protein sequence ID" value="ABX06908"/>
        <property type="gene ID" value="Haur_4276"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4276"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388742_0_0_0"/>
    <dbReference type="OMA" id="ISELWHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4328-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="571"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="735" mass="82480" checksum="14042E92416474DA" modified="2008-01-15" version="1">MQRFKRFLPLALIALSAIIFLIPPARPSIDVVMGSEGEFLVEGQTQNFRNFYGFKEVERTEQGVFRWTSGRGSIAFPYWENVAAPLQLNLLLCGCRTDGQTMPLTVTVNQQALLKLNLSNQWQWYHVQLPAGLTHPDHDILLDLTSAEWRSPDQRTLGIVVQRIQIEALAAQPTQSFVAWLGLALGLGLMVLWQIPVGFAGIVFGQWLLGVYGYQPQFLPKDFLLISLVFANVIGWQCMRNLPQLWRWVSLPLSSFWLISSPQILGSWILDDAFISFRYAANLANGQGLVFNLDERVEGFTNFLWTLLSSFSIKLGADPILVTHATNLLLGMVIVVLSLQLAHRLHQSSWMTLAIPLMLLNLPLLLYTSLGSGMETALFCAGILATVLLAINQVWGYAAIATTLTIMTRPDGMLLAGIIGLLAIWQSWQTKHWQPLIRYAGILSLTFVPYWLARWWYYGYPLPNTFYAKVGGTAKQAERGINYFIDFNRSYYLGWLGLGLGALASGLRWYQTKKVPILAIITWAIVGLYTSYTISVGGDWMPGYRFMVATVPWFALLASWGISELWHYRRWLGASAIVASSAILLLLLQPLQQERPLTVGSAAWYETDVVNRYREVGLWIKASTPPETTLTVTAAGAIPYYAERTTIDAHGLTDLHIAHLPIDPSKAGKPGHEKQDPDYVLRDRKPSLIPWVAAPMFTSHPLFDANYRLIEASGVEGRGIRMFVRRDSGLFEQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY33</accession>
    <name>A9AY33_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4283"/>
    <dbReference type="EnsemblBacteria" id="ABX06915">
        <property type="protein sequence ID" value="ABX06915"/>
        <property type="gene ID" value="Haur_4283"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4283"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037051_0_0_0"/>
    <dbReference type="OMA" id="EARYTTH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4335-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="29629" checksum="F3EA60E2883122FC" modified="2008-01-15" version="1">MHRLDQLVEDYGRTMPNEAKPAYFRLHRYRFRALLRALPAAPARILEIGTTPGTFTGILRQAGYQVAGIDLFPQDRAELWQKLNVEVKFCNLDEQPIPYGDGEFDAVVFSEVIEHLAGSPLKPLAEMLRVLKPGGRVIISTPNQFYFKSRMKTLGDVVLARPFESFKEFTRSMQLDGPQRYYNHSRLYTMAELRWMLEQAGFKVAKEFFGDAWERVGIEKGRILRHPLRVVTKAGLWVLTSLRPEWRSMLLIVGTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY81</accession>
    <name>A9AY81_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ordered locus">Haur_4331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4331"/>
    <dbReference type="EnsemblBacteria" id="ABX06963">
        <property type="protein sequence ID" value="ABX06963"/>
        <property type="gene ID" value="Haur_4331"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4331"/>
    <dbReference type="eggNOG" id="COG0163">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074522_0_1_0"/>
    <dbReference type="OMA" id="GATHIQD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="95"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="21443" checksum="80F2DD9B30F9F054" modified="2008-01-15" version="1">MSKRLPVVVGVSGASGAALADRVIERLIALEHPIELIATSSARIVWRQEQGYPWAEAVARWQASGLITEHNPNNQAATIASGSYPVYGMLIVPCSMGTVAALAAGFANNLLLRVADVTQKEGRRLVVVPRETPLSSVHLENMLRLSQRGVRLVPPMPNFYARPTTVAEVVDFVAARALVALGLSPELDSNQQWAGLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC7</accession>
    <name>A9AYC7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0861"/>
    <dbReference type="EnsemblBacteria" id="ABX03509">
        <property type="protein sequence ID" value="ABX03509"/>
        <property type="gene ID" value="Haur_0861"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0861"/>
    <dbReference type="HOGENOM" id="CLU_1439271_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-875-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="21239" checksum="0BD0514F8A939059" modified="2008-01-15" version="1">MYLAPQATFRPHQRWHWLILGWFIPALIALPWLAGPLWMTPSRSVALNRLFELPSFHTQDFAPLRIVFLIFMGFNALLYLRFIKPSSKGMVGLLIGIGITYIVYQGCMLVRANYQFWAISINDLDKYSIRVGHLLAGIGIGCVLTSVRLTVTGFSWKQIPSIILGWIASTVCGITLYTLMFGVIIQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE9</accession>
    <name>A9AYE9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0883"/>
    <dbReference type="EnsemblBacteria" id="ABX03531">
        <property type="protein sequence ID" value="ABX03531"/>
        <property type="gene ID" value="Haur_0883"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0883"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914567_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-897-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="130"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33448" checksum="092743CA6FA15D97" modified="2008-01-15" version="1">MPNPSETDVALTVIKRLRWLWLGSALVLLVGVGFLLWVGTAKQPFSLAVVLLFAAWSLIWLLLSAWLYRQIAQHLNRTILPVVRDHPLLNEQISQAKAALLAAQDQYSSHTAQLIDSILPLGVQLVSEDDVEHLFHTIVTTAKQLASADACTLYLRTSTQTLRPVTMQTDSLKINLSAFDQQLPIPALALYDNQGQPIVRTITAATVHRGVSHNVIDVYGSDSYDFSGPQAFDMAMNYHSMSLLTVPLKDSTTEVIGVLQLINCIDRAQHTIVPFSPEVQQKVEVLASLVAAALVVNDKQLPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF3</accession>
    <name>A9AYF3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cellobiose 2-epimerase</fullName>
            <shortName evidence="3">CE</shortName>
            <ecNumber evidence="3">5.1.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>D-cellobiose = beta-D-glucosyl-(1-&gt;4)-D-mannopyranose</text>
            <dbReference type="Rhea" id="RHEA:23384"/>
            <dbReference type="ChEBI" id="CHEBI:17057"/>
            <dbReference type="ChEBI" id="CHEBI:47931"/>
            <dbReference type="EC" id="5.1.3.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cellobiose 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0887"/>
    <dbReference type="EnsemblBacteria" id="ABX03535">
        <property type="protein sequence ID" value="ABX03535"/>
        <property type="gene ID" value="Haur_0887"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0887"/>
    <dbReference type="eggNOG" id="COG2942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046651_3_0_0"/>
    <dbReference type="OMA" id="WVQAETF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-901-MON"/>
    <dbReference type="BRENDA" id="5.1.3.11">
        <property type="organism ID" value="2656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047736">
        <property type="term" value="F:cellobiose epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00929">
        <property type="entry name" value="Cellobiose_2_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028584">
        <property type="entry name" value="Cellobiose_2_epim"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="416" mass="47469" checksum="D487B6E46A9EED43" modified="2008-01-15" version="1">MANLVDGGFDHGLREMWQAQFRDEVLGNILPFWANHTLDHEHGGFYGGLTNDLTIHNEFPRSAVLCGRILWTFACAYRMLGDPRDLAVAEYAYAYLKQAFWDQTYGGLYWSIDANGQPLADHKQTYAQSFAIYGLAEYVRATGDQSALELAQTLFHLIENHAFDAVYGGYIEGCDRVWQPLGDSRLSKLEPEARKTMNTMLHMMEAYANLLRVWDVADVRQQLASLIEACCEHIIDPVQGRFHLFFDDQWNHHEHGISYGHDIEGSWLLMEAAHVLGDEHLIAKAETLAIGMADAVYRNGRHADGSIIHERAPDGSINLERHWWPQAEAVVGFYNAYQATGKPEFAQAAYDSWNFIQRYFIDHDHGDWFKILDAQNQPLGAIPKVGPWECPYHHARVCFEMIERLAEHNVSVQMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH0</accession>
    <name>A9AYH0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0904"/>
    <dbReference type="EnsemblBacteria" id="ABX03552">
        <property type="protein sequence ID" value="ABX03552"/>
        <property type="gene ID" value="Haur_0904"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0904"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_5_0_0"/>
    <dbReference type="OMA" id="HAGMVST"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-918-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="48"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15261" checksum="10120DDF07283979" modified="2008-01-15" version="1">MSDDLTAIGQQILASQPFSQLLKAQISEFRQGYAELRLKINPELTQQFGFVHGGVLSYAADNAITFAGGSVLGLEVVTAEYKINYVKPAQDQELIARASVLSSGSRQAVCQCLVYCQDEQNETLVAVAQGTIMTLSSKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ4</accession>
    <name>A9AYJ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0928"/>
    <dbReference type="EnsemblBacteria" id="ABX03576">
        <property type="protein sequence ID" value="ABX03576"/>
        <property type="gene ID" value="Haur_0928"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0928"/>
    <dbReference type="HOGENOM" id="CLU_2012097_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-942-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="12938" checksum="7DD2B06A4E01B366" modified="2008-01-15" version="1">MSHNHDLLKPLRSAHGEFVTTVLAQAKAANPAPLVEQLVAHNRWAVAQLRAVPQRAGAMPPASGTMIDVSGMLAELAASCADLGAAVRDLPAEAVECGSSMVDAIIGYYHEQTARLRQGGTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN8</accession>
    <name>A9AYN8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2376"/>
    <dbReference type="EnsemblBacteria" id="ABX05016">
        <property type="protein sequence ID" value="ABX05016"/>
        <property type="gene ID" value="Haur_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2376"/>
    <dbReference type="eggNOG" id="ENOG5033EVQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159818_0_0_0"/>
    <dbReference type="OMA" id="EMHILYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2404-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="14098" checksum="7683828517616F26" modified="2008-01-15" version="1">MNILYLLHDRLQIAFMLFMIIIGIWGCFLFFTGRSITGDFWGALVIGEGLVIVEAIVGILLYIGGARPQRDIFHILYAAVAVISIPATFAFTRGRDNRFEALIYGLLGFFLMGISIRTRTTALFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYP1</accession>
    <name>A9AYP1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2379"/>
    <dbReference type="EnsemblBacteria" id="ABX05019">
        <property type="protein sequence ID" value="ABX05019"/>
        <property type="gene ID" value="Haur_2379"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2379"/>
    <dbReference type="eggNOG" id="COG4696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097934_1_0_0"/>
    <dbReference type="OMA" id="EGWQPAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2407-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023292">
        <property type="entry name" value="NTP_PyroPHydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="13946" checksum="00718F6698C4F831" modified="2008-01-15" version="1">MPDHSAAVRAFHEAIGMELPDTPQLPSLAVQALRQTLLQEEYTELQAAVNAGDLVAIAQEAADLLYVTYGLCLTYGIDLNPVFAEVHRANLAKTTGPRRADGKQLKPADWQPPDVASVLAQQAPPFRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS4</accession>
    <name>A9AYS4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2412"/>
    <dbReference type="EnsemblBacteria" id="ABX05052">
        <property type="protein sequence ID" value="ABX05052"/>
        <property type="gene ID" value="Haur_2412"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2412"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_5_0"/>
    <dbReference type="OMA" id="ATCREHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2440-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1810"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1481"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1939" mass="210291" checksum="6C291A1083683402" modified="2008-01-15" version="1">MNNLPSGTDSIKPETIETTAEILTEWLVNHFCTYLNVSSNEIDVRLPFAHYQIDSIQALSLISKLEQFLGRSLSPTLLWDYPSIATLVPALIGTEQPEVATVADSDQNADAIAIIGMSCRFPGARNLAEYWNLLINGRDAITEIPAERWNLEAVYNPDRSVPGTMYTRWGGFVDQPDYFDAGFFGISPREAIHLDPQQRMLLECTWEAFEDAGQSPQALAGSKTGVFIASVSEDYGRILFSHPEIIDAYTGPGTAHSILANRLSYVLNLQGPSININTACSGSLVAIHMACQALQTGEADLVVAGGVNASLLPDGNLFFSKAGALSPDGRCKTFDARANGIVRSDGAGIVILKPLQKALADGNPIYAVIRGSAVNSDGRTNGIMAPNRQSQEVVLQEAYRRAGVNPAAVQYIEAHGTGTSLGDVIEAQALGAVLAVGRSAQQPCAIGSVKTNIGHSESAAGIAGVIKVALAMKHQLLPASLHFETPNPMIPFEELRLQVQAQRGPWPNASGSLLAGVSGFGFGGTNAHVVLESAPIRETQSPSSNDAWPLLLPLSAQSEPALRQLAARYASQIAAASPSEVANICYSASVGRSQLDHRIAVYAASPALLSEQLNDFAEGRSATGLITQDRSQAHKLVWVFSGQGSHWVGMGRGLLAQQPIFRQTLEACDQAFRNYASWSLIEALRDDQAAEQINQTDRAQPLIFALQVSLAALWRSWGITPAAIVGHSLGEVAAAYVSGVLTLDEAVQVVYHRSRLMKQVAGKGKTAAVELTFEQARLLLVGREQQVAIAGINSPTSCILAGDPSTLEQLVASLQHNDVFARLVRGVDIAFHSPQMKPLVPELNAALAQLKPQAPIIPLVSTVTGTFAEQALYSEGYWGRNLREPFLFANAIKNLLDKGYDTFLEVSPHPVLGESMLRSIQHFKQSAQVFSSLRRDQAELDLLFETLGRLFVAGYSPDWQQVYPEPRQRSTLPSYPWQRERYWFDQLLPASSNQTSARGGFVPALLAGNLQATTSAQHPLLGLSIASAVNQSQFWQTNLAANYPAYLADHVVQEQVLLPGAAYVEMIVSALRSRGQHHVTINNLVFKQPLILPNQGQRTVQLVCNADDNGVNLQILSQAAEPDSPWELHATANALDNATPVNHSAYLALDELQARCTESIAVSEHYARMQAVQLVYGPAFQSLSQIWRGEAEALAQLQLAPAIGQLAQHDQLHPALLDATFQLVAVMLAQHTNDQTYLPIALERLNVLDRIPAEAWCHAALRSAPADETLMYEADLVIADAQGRVVVEIAGLKLFQVAAARNANQPQQALYDYRWQPIEIQTIEHPAERWLILANTHDQFAKQLSNSLAAHGQQVDCLEQSIEANGLGDWLKTQLQANYQQIVCLWPLAASNDHAPVTSATQQSLAMLTLLQTLSDSGSATPRLWCVTRGAQAVLDHEVINLAQAPLWGMVRSAALEHPELAPSLIDLAPMAESNEASQLAKTLLQRANEHQQALRNQQQLVARLQQRPITKSTTLKLSNQAAYLITGGSGGLGLEIAHWMLAKGASNLIILGRRPLQPSHNAVSEQQSQLVNALSQLEQAGANLRYAAINVADQAALAEFLQQYRAETGLAIRGIVHAAGVLDDQMLYRMQPSALTSVFAPKVAGAWALHEVFSQEPLDFMIFCSSLAASIGSVGQAHYAAANSFMDSLAAYRRSQGLVGLSINWGPWAEVGMAAKLNPQLFEAHGVQLLQPQQALVAMEQLINDQAIQTTIAEIDWATWLKNNQVVATLPFFAALAPSTTIAQTASNLTQEHEFRQRVLQTQPSERQALITQQLKQLIAKVMQLDPSKLDSQLALHTLGLDSIMAIELKTSISQNLGVTLSVAYLIQGPSIDEIVANVNQQLSLELSSEMFASPETRDDALQVLLEQVQQSDHDQIAQILAELEQLSTDEAKSRLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU4</accession>
    <name>A9AYU4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2432"/>
    <dbReference type="EnsemblBacteria" id="ABX05072">
        <property type="protein sequence ID" value="ABX05072"/>
        <property type="gene ID" value="Haur_2432"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2432"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_0"/>
    <dbReference type="OMA" id="YSMINRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2460-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="36446" checksum="3432AF7F958FC8A2" modified="2008-01-15" version="1">MIYQAKDSRYTSMRYNRSGKSGLKLSAVSLGLWHNFGGVDVYENGRSMVLHAFDHGITHFDLANNYGPPPGSAEENFGRMLQHDLKPYRDELVISTKAGYYMWAGPYGDWGSRKYLVSSLDQSLKRMGLEYVDIFYHHRPDPETPLEETMQALDQIVRSGKALYVGLSNYSAEQTAAASAILRQLGTPCLIHQPSYNMFNRWVEGGLLATLAEQGIGCIAFSPLAQGLLTDRYLQGIPGDSRAAKSHGFLKPAHITDSALAKVAQLNDLAQARDQTLAQMALAWVLRHPTMTSVLIGASRISQIDDAITALNNLTFSDEELATIETVLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYW0</accession>
    <name>A9AYW0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4368"/>
    <dbReference type="EnsemblBacteria" id="ABX07000">
        <property type="protein sequence ID" value="ABX07000"/>
        <property type="gene ID" value="Haur_4368"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4368"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4421-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="31832" checksum="43726C2FEB794B5A" modified="2008-01-15" version="1">MSSFLADDQNPIFYSDTGGQKPAIIFIHGWTSAGSHWVGITTALRRWYRCIAIDLRGHGRTPGQGELTISRLAKDLHQLIEHLKLEQPTIVGWSMGGLTTFEYARQFGVSQLKSIVLVDQTPCMQTSTEWTMGLFGAYTPDHITSMRQLFESQQRRVLRRFAMGVVHPNRTLLRFATWLTSPYRRNYDRKALLPLAEDMADRDYRDLLASMDVPILLCYGSQSWLYPGKVGEYLHEHLPQSTLIHFERSGHCPPFEEPVKFVRTLYQFMHQQLPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYZ9</accession>
    <name>A9AYZ9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4407</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4407"/>
    <dbReference type="EnsemblBacteria" id="ABX07039">
        <property type="protein sequence ID" value="ABX07039"/>
        <property type="gene ID" value="Haur_4407"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4407"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_2_0"/>
    <dbReference type="OMA" id="QVGVAPK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4461-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12263" checksum="76D0C1893139A745" modified="2008-01-15" version="1">MAKPLAVSDAEFESAVINSDIPVLVDFWAPWCGPCRSIAPVLEELADEYQGKLLIAKVNTDEDSGNAMKFGVQGIPTLIFFQGGQEVDRIVGAGPKKIYQERIEAILNPVTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ06</accession>
    <name>A9AZ06_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4414</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4414"/>
    <dbReference type="EnsemblBacteria" id="ABX07046">
        <property type="protein sequence ID" value="ABX07046"/>
        <property type="gene ID" value="Haur_4414"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4414"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044815_1_3_0"/>
    <dbReference type="OMA" id="RPWLIAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4469-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="23956" checksum="8B3D4BCB25BA57AC" modified="2008-01-15" version="1">MTHAAATLAAIAEEVAQCTACPLCRTRTNAVPGEGPANAEILLIGEGPGQREDALGRPFVGPSGDLLEQWLAEIGLTREQVFIANVVKCRPPGNRDPEPSEIAACAHFLDRQIAALAPKLIATLGRHSMNKFFPGGKITKIHGIRGVKRQGQTVFLPLFHPAYVLRNMNAMPDAIADIKLIPRLIARLNQRLQEETNETTEPNLPETDEPTTPPQQMSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ57</accession>
    <name>A9AZ57_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0955"/>
    <dbReference type="EnsemblBacteria" id="ABX03603">
        <property type="protein sequence ID" value="ABX03603"/>
        <property type="gene ID" value="Haur_0955"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0955"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_0"/>
    <dbReference type="OMA" id="IRWMGAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-969-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="102"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="31482" checksum="A06AEC011E93FC19" modified="2008-01-15" version="1">MNHVELFESYRGYVFGIAYRMLGSVMDAEDCLQETFLRWQSHAEQVENPRAWLATVATRWCLDQLNTARHQREQYIGEWLPEPLIIAAPSSNVEQLESLSTAFLVLLERLSPAERAVFLLHKVFGYEYSEIAEIVGKTPAACRQLGHRAADHVAQARPRFKVEPSVQQRLSEQFLQSCATGDLNGLMSLLTEDVVLRSDGGGVVQAARNPIYGPTAVGRFLLGVLPKLPANSIFEPRLINGQAGFVALVDGQASGTLILDMLDQQIAGIYIMLNPQKLQHLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ92</accession>
    <name>A9AZ92_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0990"/>
    <dbReference type="EnsemblBacteria" id="ABX03638">
        <property type="protein sequence ID" value="ABX03638"/>
        <property type="gene ID" value="Haur_0990"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0990"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_539365_0_0_0"/>
    <dbReference type="OMA" id="TCGMPLI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1006-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="37"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="313"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="486" mass="53854" checksum="EDC3DCE8154B2AE6" modified="2008-01-15" version="1">MSIATERTLCPICGTDNRNDAKFCQQCGNNIVLNNRYRITRAIKEGGMGAVYAATDQSGKRYALKSLIDRFNDKAERDEAIERFKEEASILRELQHPQIPHVYGDFLHGGRYYLAMDFVEGDDLEDLQRHQANEQFDEPTVLHWAEQIANVLDYLHERRLIYRDVKPSNIMIERKTGNVKVVDFGIAKLFQPNERGTLIGTPGYSPPEQYQGQATPQSDIYALGATLHHLLTGRDPRDEAPFSFPPVRQLAPKVSAATEQAISKALEMEISKRWKSAAAFRAALPLESLHKPKPKPKPQPQATVILEQKPQKPAMAASVGAIPQPQKAAPTSSTKPKPKPKSQPLPAKPKPAAKPQKRFRPWIPLLTIIIVGVLLALGIPGMDQKILNLFNSSTTTSVTPIPQAATTRWVERNIVVSVAEGTNDTEIANQLKQQYRQAIVAEFGNTAKINEALMTFVGGNPRNIGTDASGIRYEVTIRASVAIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD2</accession>
    <name>A9AZD2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WYL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2436"/>
    <dbReference type="EnsemblBacteria" id="ABX05076">
        <property type="protein sequence ID" value="ABX05076"/>
        <property type="gene ID" value="Haur_2436"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2436"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450390_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2464-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="541"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="606" mass="67777" checksum="A5E0BE4E193C2165" modified="2008-01-15" version="1">MAYSSSAVKLHATNALHAVAVRTLRTLAHYTDCSRQRSQTGHALAAALQRHWQTPHYRQLVRRSLTAADRALLQAWWQGQQPLPTPQALDLWRWQAPWPTLEQLSSEQRLAALGLVVPIRTTTGRTVVLINDTSRWLRRTPPLPPTPVAASLQALFQAVVALLAACANTPQPRQAAGLALHIAQSAGWLADRLNQWRITPRGRVWLHSPIAEQQRLLHQQLITCNPPARGLVAWRSPDWAALFADLERLMEAQAQRRSMDVAALLHDHPAWNGLPAAQQIRLVHGWLCTVLQPAGVVSLAKGWLFWHGWQQLAAQAPAFDGLRLPKRAALPAALQVWGLTWGMATSHGWRITHASVTARLQQGLDLNGFWQPIDQWYAERPALIQALIAKLQATPPLRLRRITLLEGSPEAVASAHANWQIQAYLQPGFDQAQRVVCQGAEQVVAKVLGLHATPTPSLDTQTSIQIMALRIAAQHLPSHRLAFNQQAQHLLAELSFEQRCIIDDDWERLQLSDAPDLLASSQALAVGQQPRAQITVEQARQTCRQAINNQQSVTVRYYTPAEHRITTRTIRPLELTSTGMRGWCELRQQERAFRFDRILAIEANTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR5</accession>
    <name>A9AZR5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="17" type="ordered locus">Haur_4487</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4487"/>
    <dbReference type="EnsemblBacteria" id="ABX07119">
        <property type="protein sequence ID" value="ABX07119"/>
        <property type="gene ID" value="Haur_4487"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4487"/>
    <dbReference type="eggNOG" id="COG1207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_15_2_0"/>
    <dbReference type="OMA" id="TAIVEHK"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
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        <property type="entry name" value="GlmU_C_LbH"/>
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    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
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        <property type="entry name" value="MobA-like_NTP_Trfase"/>
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        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
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        <property type="entry name" value="Trimer_LpxA-like_sf"/>
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        <property type="entry name" value="SSF53448"/>
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        <property type="entry name" value="glmU"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
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        <location>
            <begin position="1"/>
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            <end position="253"/>
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            <end position="459"/>
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        <location>
            <position position="22"/>
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        <ligand>
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        </ligand>
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        <location>
            <position position="140"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
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        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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        </ligand>
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        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
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        </location>
    </feature>
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        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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        </ligand>
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            <position position="353"/>
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        <ligand>
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        <location>
            <position position="368"/>
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        <ligand>
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        </ligand>
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        <location>
            <position position="379"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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        </ligand>
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        <location>
            <position position="382"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="408"/>
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        <ligand>
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        <ligand>
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        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX07119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="459" mass="48817" checksum="AAC788BF19F48308" modified="2008-01-15" version="1">MTLGVVVLAAGQGTRMRSSLPKVLHPVAGLPLVEHVTRLADAVGAQQIVLVVSEDTLAPISAAFGHRYRYVVQHERLGTGHAVAQARAELEGKVDEVLVLYGADPLMRHESLLELLAVRRTTNAKAAIVSFQANPPTGYGRIVRDETGAVQAIVEERNATPEQRRITEVNQGVALYDGAWLWNALDQIQPNSLNGEYYLTDLVEIALHEHGLGAVAAIQLRDPDEALGVNDRIQLAQVGAILNARKIRALMLAGVTVVDPATTFVDHDVQVGMDTTLLPGTILKGRTTIGANCMIGPNSLIEDSQIGDHCKISYSVVEQAQMDLGANIGPYGHLRRGAHLMEHVHMGNFGEVKNATLGAGTKMGHFSYVGDATIGENVNIGAGTITCNFTADGKKHRTEIGANAFIGSDSLLRAPVKIGAGAITGAGSVVTKDIPDGGVAVGMPARVIRHRKLEQSENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B017</accession>
    <name>A9B017_HERA2</name>
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        <submittedName>
            <fullName evidence="3">PSP1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1076"/>
    <dbReference type="EnsemblBacteria" id="ABX03724">
        <property type="protein sequence ID" value="ABX03724"/>
        <property type="gene ID" value="Haur_1076"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1076"/>
    <dbReference type="eggNOG" id="COG1774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033149_2_1_0"/>
    <dbReference type="OMA" id="SFEQENY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1096-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="61"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="451"/>
            <end position="483"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="508" mass="57493" checksum="60C9CFED34AF7E98" modified="2008-01-15" version="1">MPLVVGVKFKDSGKIYHFDPNQHHLELGDAVVVETVRGLELGKVAAPIEDLPDSDLIAELKPVIRQPTTEDYDRMRVLAERRDDVLRICAERISVHRLPMRLIRSDWNFDGTRLTIYFTSQQRVDFRHLVRELARIFHARIELRQIGARDEAKLLGGLGPCGRPLCCSTFLPDFARVSVKMAKDQDLPLNPSKISGVCGRLLCCLSYEQEQYLEIKAELPTRGEQVKTPEGIGYVVAVNTIRETVTVDIESNYHDFKADQLETLTGAAGAIARERLEQGEAAPIAQKRFNRPVGETIKSTLNNWDNEDWGLDELRSFEEDPESSGDKPKPRPKPAQQARPNPEAREQRTNPNEQRPRFDRAERQKRFNRSEAANAEASVAPTPSNEPSERKPRHAFKRKGDTTPTPERPKLPATVRQQSLGGVPEQLTPRGRQPSTNDPDEPKQPNRRRRRGNGGNGNQQGQQQVQPKPNQPQVTSSKPSTVEKTESESAKPEANNERRSPRRRKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B028</accession>
    <name>A9B028_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24504" checksum="E4BD00708D245A78" modified="2008-01-15" version="1">MQTTRPRGRPRTFDRQAALDAAMELFWRHGYEGTSIADLTAAMGFTPPTLYAAFGSKEDLYREVIQHFLLRSERQRMEAALNQTSAYAMLRYYLYAAAESFTDPSTPAGCMVATAALQCAVENQPIVQEVARIRHQMFIGFVERLDVAKRNQELPETIDSLALANFYTAIVQGMSVQAIDGASSADLIAVADLALSAWPGEKSEGKSQKAKVQRDQDSGIRG</sequence>
</entry>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="20547" checksum="23B4F83AFB34E9EC" modified="2008-01-15" version="1">MTTQVSNRLTRSATDRRFAGVCGGIAEYLAIDSIWVRLAFVFLVMTGISILLYPLLWFIMPRGAVSYLAQTTQAVQQPVSYQVAQSVGVQPSVNARFDPMTGQAIKAEPYRFDPVTGQPIGQGIPVNNIATPVATVSPDVIKARRNLWLKSALVIGGALFLSSILVEIAPVLIPVGLVVAGVWLIRNNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B062</accession>
    <name>A9B062_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
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                <person name="Brettin T."/>
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                <person name="Detter J.C."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
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                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
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                <person name="Tice H."/>
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                <person name="Richardson P."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX05171">
        <property type="protein sequence ID" value="ABX05171"/>
        <property type="gene ID" value="Haur_2533"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2533"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="WVGCGRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2561-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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        <property type="entry name" value="TPR_repeat"/>
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    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="SSF52540"/>
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        <location>
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    </feature>
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            <end position="702"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05171.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="798" mass="88814" checksum="AF0DC243AF61279C" modified="2008-01-15" version="1">MNQHLWQVEWLQQLLQQPHIALNQPAIKQLVHAKGGLHPLLQWLCQQPLQPDQQRLLQLIVAEPQRSIAYYADSLGIHATTYHRHFKKLCQYLLTRLNDGIAEPQASASFNLPIPPTRCLGRGNEQQTINRLFAKGQRLISILGFGGVGKTRLALAIAEIQQAHYRDGVCFCGLASISQPQLVLATIAEALGVAIGPQQTPEKALQQFLAKRQILLILDNVEHVVEGVAAIGQLLREAPQLQILATSRVPLNLYGEYMLQLQPLVVPTKPIASQDLAETPAIALFIERAQSHAARFSLDDASLEAIRQICSQLEGLPLALELAAAHTRVLSPQRLVQQLSNHVLGLKTSIRDLPERQRSLRNLISWSVDLLAPSQQQALQALAIWPAGWTLSSASFALDLAEDDPALYDILANLVDHHLIMQVPHAERWVLHPFVREYVLEQLAPAQQQQFAQQHLAWATQLSEAFNQHFAAAQQQWLDLFEAEHDNLRAALAWASSNHYPIAALNIAVNSWRFWWARSYFNEGQQWLDQTLAQATSQTQKLEPTLHSRALNACGAIAWSRGDIAAAQAHFSQSLALYDANNNPIGAAMVRNNLALVAIKQQAYAQAESLFELNAAVFGSTVEQAANYAATLSNLAMLARYRGDLERAYDLAQQTLTLRQTLNNQWATATSLTNLGAISLQRGEFQPAQRYYQQSLQVLHQLGERESIAECLEGLAILAIQAGQYQLGAQRLIVVEHLRESIGAPRSEPEQALLAPWISQLEQQLDLGIRQQLRQQTSLDRLESMIEQALNEGVEARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B093</accession>
    <name>A9B093_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2564"/>
    <dbReference type="EnsemblBacteria" id="ABX05202">
        <property type="protein sequence ID" value="ABX05202"/>
        <property type="gene ID" value="Haur_2564"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2564"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_0"/>
    <dbReference type="OMA" id="GRGHFIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2592-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="28956" checksum="583EEAE7EA6EA01E" modified="2008-01-15" version="1">MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSADVRDPEAVQQVVATVIDEVGTPNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLCHAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAIVRLSETLAMELKRQKIRVNCIGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLITVHDAYEQLSSQLVEINHSSRYTLRRIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E0</accession>
    <name>A9B0E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05249">
        <property type="protein sequence ID" value="ABX05249"/>
        <property type="gene ID" value="Haur_2611"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2611"/>
    <dbReference type="HOGENOM" id="CLU_1560835_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2639-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19259" checksum="4E76CC302C1970E3" modified="2008-01-15" version="1">MQPFLLDPKNAAVVTRQKPYGSGKFMLFMLLFSLPFLFVGCGALGFLLRDVGQAESQTDWNSVSIQLAFVILFGLFGSLALYFFVLRPWRLAKALRERGQMLPGQIINARFEKDSDGDWNLVINYQFVSPQGIGITKTQSHIRNDLRNTPPPPANTPVVVMYADDRNFTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F6</accession>
    <name>A9B0F6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4543"/>
    <dbReference type="EnsemblBacteria" id="ABX07174">
        <property type="protein sequence ID" value="ABX07174"/>
        <property type="gene ID" value="Haur_4543"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4543"/>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_758144_0_0_0"/>
    <dbReference type="OMA" id="WDAFVTM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4598-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="40195" checksum="706BAB43607F5138" modified="2008-01-15" version="1">MLTQIRSRKRLLAIGAAVLVFFFIVTTLLNGSGNSASDKFQTVSDALDQAAMPESAPAAEMERQVTTDGLMDESDVAAAPALGGAAPADAENSQEPSAAPNQATDRLVIKNADVEALIDYKQMRLASTQIENMVLRLGGYIVLTDDASSNDEDQAYISLAFRVPADQFEKALNAFEENKLEVVRREVSGQDVTEEFVDNQSRLTNLEATAARIRELLAKAETIADTIKINETLAQYESQIEMIKGRQKYLSDSASMSMITLLIRPKTADYSMFTKIDIGQNIRNALAKAERPGWTPLAAATGAWDDVLEIGKDVAETLVVWAVWLPIWLPLVLAAWFGWRKWRKYSQNQSQNSPITNQNPPVNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J8</accession>
    <name>A9B0J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4585"/>
    <dbReference type="EnsemblBacteria" id="ABX07216">
        <property type="protein sequence ID" value="ABX07216"/>
        <property type="gene ID" value="Haur_4585"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4585"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_541602_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4640-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000413">
        <property type="entry name" value="Integrin_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01185">
        <property type="entry name" value="INTEGRINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735155" evidence="4">
        <location>
            <begin position="25"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="503" mass="50419" checksum="271E200BD2C49562" modified="2008-01-15" version="1">MKLRQLLGLCGCGIALGLSGWAFAESPQFSESLAETTIVAFTGGAGEHAGYAVADAGDINQDGLADSLVGAWVADPLGRNNAGTSYLIWGQALTATLQAPDLAERGVAIYGASEGASSGWSVTGLGDVNGDEIDDFAIGAWGESPNNRATAGSVFVVWGGSLTTTLDLAALGNHGYRIDGAVAGDRLGYALAGVEDLNNDGLNEIVIGAIGVDASADNAGAAYVVWGKTTTTTLDLATASNYGYRIDGAAASDRAGSAVGSTSDMNGDGKPEILVGSYVADPFGRSAAGSVAVVWGANTTASYPIGALAQNGFVIAGAGASDRAGISLVGTGDLNGDQRGDLAVGSDQFPAGGAGRVDLIYGSAFSGTLDLAQPLSNTVRFVGEQAGDEAGFSVGYSDQRLIIGAYGVDSSLGTDTGRVYVVNTPSISNTINLANLTIEQGFSLDGVVGGGRLGRAVAGLGDATGDGHGDLLLGADLAGSQIEGYAYIVGRLPTTVYLPMIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N0</accession>
    <name>A9B0N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ppx/GppA phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4617"/>
    <dbReference type="EnsemblBacteria" id="ABX07248">
        <property type="protein sequence ID" value="ABX07248"/>
        <property type="gene ID" value="Haur_4617"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4617"/>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025908_4_2_0"/>
    <dbReference type="OMA" id="RISEGCY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4674-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="2">
        <location>
            <begin position="27"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="344"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="502" mass="55849" checksum="F37E7D86F7A723D6" modified="2008-01-15" version="1">MTQHVGIIDLGSNTARMIVVQYQPYYSFKLVEEVKENVRLAHNVGADNQLQAEPMAMAIETLRMFSNFCRALGVNEVVAVATSAVRDAANQASFLAQVKEETGLDLRVLSGDEEAYYSYLGVINTLGVSNGFMFDIGGGSVELALVRGRGLAHTTSLPLGTVRLTEQILRSETPSKAELKALDRHLDEALAELDWFRPQGSKLPLIGVGGTVRNLAKLEQRAQRYPLDIVHGYTMSLQRVDEWATRLSKLNRNEREQLDGLNNDRADVITAGVLLIRALMQRCGADSLWICGHGLRDGIFYEQFLRGSQPPLLGDVRQFSVENLARIYGYNVVHVAKVRELSLALFDQLQSLHGYGAWERELLEAATVVHDIGVAVNFYDHHKHGLYLILNSMLNGYTHREMAMVALLTRHHRKGGVTDAGLGGVLAEGDLERVGKLSALLRIAEYLERSKSQVVQSIVCKIEKNQVRVKVQAVGDASIEIWDANRKTNLFRKVYGVEMLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T3</accession>
    <name>A9B0T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1155"/>
    <dbReference type="EnsemblBacteria" id="ABX03803">
        <property type="protein sequence ID" value="ABX03803"/>
        <property type="gene ID" value="Haur_1155"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1155"/>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065178_0_0_0"/>
    <dbReference type="OMA" id="ESFPREV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1177-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="133"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="29034" checksum="62A92BBCD0E761FE" modified="2008-01-15" version="1">MLIDRQLAAQLEAADAHNLRQYTAAVAQVVPASQATWAQIGDATACYTGPDLPINRAVGAGSQQPWQARQFGELEDFYRQRQLPASLELTPFCDPSLQGVLAQRNYQIIRWWSVLAFDMLRYTPFSPSSVQSRMIAPEQSELWVEGITNHGQSSPMGITMAKAAAARSDSQLFGAWLDDHLIGCGALSINAEVATLFSTFVKPDWRRRGAQTSLIAARLAYAHAQGCRWATVLTISGSDSQRIVTRAGFELAYNKVTLEEQRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U9</accession>
    <name>A9B0U9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1171"/>
    <dbReference type="EnsemblBacteria" id="ABX03819">
        <property type="protein sequence ID" value="ABX03819"/>
        <property type="gene ID" value="Haur_1171"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1171"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049009_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1193-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735161" evidence="1">
        <location>
            <begin position="23"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26449" checksum="F5F9005DDBEB43B2" modified="2008-01-15" version="1">MKQLKCLMLAMLLIVPIRASTAASSYCFPELKAHCVEAPFDDYWRDNGGLPVFGYPITAKERYQAPDHGPTLSIQWTERQRLEHHSNLTGTPYEIQIGLLGKERLAQLNRELEPAARRPAADCLWFGETGHNVCNQDLGMGFKQYWESHGTTTAGLDSYGRSLQLFGLPLTSAQYEINADGDQVVTQWFERARFEWHPDNPDQFKVLLGRLGSELTGLEPVIEPEPIPGPNPPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V7</accession>
    <name>A9B0V7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1179</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1179"/>
    <dbReference type="EnsemblBacteria" id="ABX03827">
        <property type="protein sequence ID" value="ABX03827"/>
        <property type="gene ID" value="Haur_1179"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1179"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_0"/>
    <dbReference type="OMA" id="LTMTNGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1201-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="146"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="40765" checksum="B7157D2A99C2197C" modified="2008-01-15" version="1">MSSQPQTSTNTEPRSRNNVGLAQMLLVPLALLISILVGRWSLGVMKDAEAPRLLVVGVALLVGVFGIWIAYWLCNELLNLIPSETLREKIRPIIFVGPALALLIIYLVYPTVMTAYYSVLDKNSEAFVGLDNYTFAFKNRTIQIALRNNLYWIVGVTTFSVVGGLIMAVLFDKVRYESVAKSMIFLPMIISFVGAGVIWRFMYASNPPGVGLLNAFIGNFDYKPVAWLINKSVNNISLIVIMIWLQTGFCLVILSAALKAIPADIIDAARVDGAGELDIFWRIIIPSLKTTILTVVTTVVIAVLKVFDIVFVMTNGNYETEVIANRMFTEFFRNQNYGLSSALTMILVIAVLPVMIINVRNARRQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B142</accession>
    <name>A9B142_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2682"/>
    <dbReference type="EnsemblBacteria" id="ABX05320">
        <property type="protein sequence ID" value="ABX05320"/>
        <property type="gene ID" value="Haur_2682"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2682"/>
    <dbReference type="eggNOG" id="COG5349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133146_1_0_0"/>
    <dbReference type="OMA" id="GMAINTV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2712-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009325">
        <property type="entry name" value="DUF983"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06170">
        <property type="entry name" value="DUF983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13779" checksum="EFE28775F0D959B5" modified="2008-01-15" version="1">MFNALLMLWRGLGGRCPTCGYGHMFKTFFGLIEGCPACGLRFEGTGDQSTGAMGISLTITVALGFAGALILVWQWPDHLILGTAGLIGVLSIFQLFCYRVSRGFWIGILAITGAIHEDERRDQFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D6</accession>
    <name>A9B1D6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ychF</name>
        <name evidence="3" type="ordered locus">Haur_4692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4692"/>
    <dbReference type="EnsemblBacteria" id="ABX07323">
        <property type="protein sequence ID" value="ABX07323"/>
        <property type="gene ID" value="Haur_4692"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4692"/>
    <dbReference type="eggNOG" id="COG0012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_0_1_0"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="275"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="360" mass="39557" checksum="C2F6DA0E4EA6C596" modified="2008-01-15" version="1">MKIGIIGLPNSGKTTVFNALTRNTAETNAYSSGQIEPNIAMVKVPDERLDALAKMYKPKKLTPADVQYIDVAGMSGNAHESGGLNPQFLNYISQVDALLHVVRAFEDEGVPHPQDSVNAARDLASVDMELMFSDMAIIERRLSRLRGEVTKMVGKDREVRLMELNALERLYTGLEQDVPIRAQELSEEEAKVLRGFQFLSGKPMLVVVNIDEKQLKTPPVLAYDKPKTAIVTLAGKVEAELAQLEDEDAQMFMDDLGITEPARDRVIKASYTMMGLISFLTAGDDEVRAWTIRQGIGAAEAAGTIHSDLQRGFIRAEIVAFDDLMKAGDMAAAKKAGTVRLEGKTYIVKDGDIAHFLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F3</accession>
    <name>A9B1F3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnhA</name>
        <name evidence="7" type="ordered locus">Haur_4709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4709"/>
    <dbReference type="EnsemblBacteria" id="ABX07340">
        <property type="protein sequence ID" value="ABX07340"/>
        <property type="gene ID" value="Haur_4709"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4709"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030894_0_4_0"/>
    <dbReference type="OMA" id="ELWYGLY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="83"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="25897" checksum="F61D7387629484F3" modified="2008-01-15" version="1">MAKRKFYAVVKGRQPGIYNEWFGNDGAEAQVKGIDQAVFKGFASFADAEAWYRERAGRAPQRIPQNVDLTPVSLAIDPQKALDEGKVVLFSDGGSDGNPGPGGYGVVLRSGSEMRELTGGFARTTNNRMELMGVITGLQALSQPSKVVVYSDSAYVINGMHKGWAERWSKNGWRTTTGPVKNPDLWQQLLELAQGHTIEWVQVPGHAGVKDNERCDRLAVQAAHQPNLPIDQGYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q3</accession>
    <name>A9B1Q3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03938">
        <property type="protein sequence ID" value="ABX03938"/>
        <property type="gene ID" value="Haur_1290"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1290"/>
    <dbReference type="HOGENOM" id="CLU_2287634_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1312-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731793" evidence="1">
        <location>
            <begin position="27"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="101" mass="10187" checksum="3624222BE2113913" modified="2008-01-15" version="1">MKNMVKRLLLSGLLVGMTLLPVSASAAGSAGIYASCSNGARVNVSGSGNITVTFYRLNASPIVKYINLGVGMSTTVYSGTSGSYSTVYANGNSSVSGAGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X1</accession>
    <name>A9B1X1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2775"/>
    <dbReference type="EnsemblBacteria" id="ABX05413">
        <property type="protein sequence ID" value="ABX05413"/>
        <property type="gene ID" value="Haur_2775"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2775"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_747401_0_0_0"/>
    <dbReference type="OMA" id="AYCSHAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2806-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="5">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="38596" checksum="7CA2BD9E77C3133C" modified="2008-01-15" version="1">MASSVALPTFQSTARLYRWLIQPGAEVAAGQLVALVVDAHAEWALPAQQTGTVAALLVDEGATLDVTTPLLQFVEMVSKRQLTVTPLARCIAERHQLDLSTISGTLADGRVGKRDILAHLPDVSPTLAEPTEQLAAPADGFCVAEQMGNAFAQSEQVIVVAAPKNPPISQTTPPQASTLQPWTEAQLQQIQLRQLAAASIPQAYCSHAISLDRFASTELTAHLLLATIQVLQRHPLLRSVWSAGDRLERASLHIQVEHPLGRCSIPFAADLNLRGLQRALTSPATEQAGVFSFIQSAVNLWSAAPINYGQSATLHIGATRKVLVGEALQISQQAIATLSYDTRLISDAAAEAFLADLAKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B206</accession>
    <name>A9B206_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MBOAT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2810"/>
    <dbReference type="EnsemblBacteria" id="ABX05448">
        <property type="protein sequence ID" value="ABX05448"/>
        <property type="gene ID" value="Haur_2810"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2810"/>
    <dbReference type="eggNOG" id="ENOG502ZT7B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_885015_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2841-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="MBOAT_2" evidence="2">
        <location>
            <begin position="180"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="35741" checksum="3A0F75A7B3E50A5E" modified="2008-01-15" version="1">MQTLLWWIYWPLSWLLIVASAWYLPNRWRNSVGWSILGFGGALSLYLAIDLDPWQRLLTSTAGLILLLKAVVLLQIPRQELQRYSHVGLGLFMTIWPGMNPAPFRQRRQIQRDLGPTIIQGWVGVMAGSCGLILSAYLLPWLGQAWASWAAILSILGIVHFGLAYWLNAGLWYWGWPVAALFRQPLQSRSLRDFWSVRWNIAFVEMNKQLFLRRLGRYGPSTLVIGIFLLSGIFHELGLSYPAQAGWGQAMAYFGLHAGLMWLERTFNLAQRWPQWILSCWTWLAILGPLSWLFHQQFRQALIVPALHWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B293</accession>
    <name>A9B293_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Hydrolase of the alpha/beta superfamily-like</fullName>
        </submittedName>
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        <name evidence="2" type="ordered locus">Haur_4813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4813"/>
    <dbReference type="EnsemblBacteria" id="ABX07443">
        <property type="protein sequence ID" value="ABX07443"/>
        <property type="gene ID" value="Haur_4813"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4813"/>
    <dbReference type="eggNOG" id="COG2945">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086287_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4872-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="50"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="23098" checksum="17B24811FCCA75C4" modified="2008-01-15" version="1">MQTTIHFLSADGSTLLEGKWLALSQAPQLVAVLAHHFPPMSNMDQRAIFATFKVLRDRGWGVLRYNSRGVGQSQGEFSGGPGEDLDLQAALAEARQRAPQAQICLIGWSFGAQLVLRVMASDPTIRATVAVTPNPVGLQESAQGQHGPLLAIVAERDQFFDLIETRTAFEQATEPKTWHLLKWADHYYLTREDEVAQFTVDWLEQAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E4</accession>
    <name>A9B2E4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03989">
        <property type="protein sequence ID" value="ABX03989"/>
        <property type="gene ID" value="Haur_1344"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1344"/>
    <dbReference type="HOGENOM" id="CLU_2301982_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1365-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="11115" checksum="5AAEC40F768A6F72" modified="2008-01-15" version="1">MPTYEHQVARLWTGIRSLCLGYRYEHRLRGAYAQLLLVNRDVVGDLLDEYHALVRAFALYGGMGGGANQPLAGAITVEGFELIVDLYLSFYQKVRAGAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E8</accession>
    <name>A9B2E8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03993">
        <property type="protein sequence ID" value="ABX03993"/>
        <property type="gene ID" value="Haur_1348"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1348"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1600445_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1369-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="41"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="17832" checksum="1981F805B3187C97" modified="2008-01-15" version="1">MTQPNSLHQIMTALGGSLSSDKGDSTDYIVPLPTFDHTSVVQTLFTQLAHVTPGVLGSVLMNSAGDVLASTLPDHLNVMQVTAISGPWLRIADKVAQSVGLGHTEESLIRTAEGFCSIRPIHSHIVITVLRSQSNLGFFWLNMADMEQLLISVLAGIPLDHDGSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K2</accession>
    <name>A9B2K2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <property type="protein sequence ID" value="ABX05453"/>
        <property type="gene ID" value="Haur_2815"/>
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    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_019327_1_0_0"/>
    <dbReference type="OMA" id="SHDICSA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="entry name" value="Amino_oxidase"/>
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            <end position="337"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="522" mass="55685" checksum="6A776C50ECB1A311" modified="2008-01-15" version="1">MDSYDVVVIGSGHNALIAAAYLARAGKSVLVLENNDRIGGLVRTEELTLPGFKHDVYSSAHPLFTTSQAYADLGADLTARGLRYINTDIPTGVSFSDGRTAILPQAFEAALAEAERLATGDGAVLGQMLASFNPYVEDVFGLFSMDLQSPTAQTMIQRLLRSETGYSPFSKLLFETARNVVSPFQSPVMQAMLAPWVMHLGRTPDEIGSGLWVYLIVLATMGAGMATPEGGSEQLARALGSLISDHGGVIRTQTAATRIVLSNGKASEVHTNTGEAFGVREHVIASVNPDQLYLRLLADSPQPEHVLQQAKEFRYGRGCVQIHLALSEPPRWPDARFNRIGQPHLTDGLNQCTLAVAQAMAGLLPINPTFTVDCPTNLDPTRAPAGKAIMRIQVLEVPCRPIGDAAGQIAVGDGTWTGDLTQRFVERILAIVERHIPNIPSSVVGLHTVTPTSLAQFSPNLGPGDPYGGAHDLAQSYLLSPLPAQPSHRTLVPNIFMLGAATWPGHGINGGSGYIVAKQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
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    <name>A9B398_HERA2</name>
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        <submittedName>
            <fullName evidence="3">Protein serine/threonine phosphatase</fullName>
        </submittedName>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1417"/>
    <dbReference type="EnsemblBacteria" id="ABX04061">
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        <property type="gene ID" value="Haur_1417"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1417"/>
    <dbReference type="eggNOG" id="COG2208">
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    <dbReference type="OMA" id="ETRIAIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1439-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF81606"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="42"/>
        </location>
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            <end position="111"/>
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        <location>
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            <end position="140"/>
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    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="183"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="44106" checksum="8AC4375A7F64362F" modified="2008-01-15" version="1">MQPARTSHNYTPMPFRRLLRWSMMLSTVLGFIILIPVATSGLNVENVLMTFGSSYSIGLAAPSLVFFLLRWTMPIAQRRNWSPIRAWSLAAFLGGLIATIIYAVIFGLFFIPANERLSFSIFWTILGSLLSAGTTGLFYTAERVLNELDKGRQALRHNAALSEELRLARMIQEGLLPDHPPEINGLAIAGGCFPAHEVGGDLLSYDLTADGRLCLSVGDVTGKSVSAAMLMGITLGVLQSEIYDHEEPATVLSELDRWLRTKRQTNNFVALQVALFNPQTSSMLLANAGQLAPLRRRQHEVEFLEIKGSLPLGMGPTMPHVQEQVSLQSGDLLVFYTDGVVEAQNAKGEMWGFESLITLIKTIKSNHPHEIVQAILTAIRSYTHNIEPHDDITLVVVAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C8</accession>
    <name>A9B3C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
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    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1447"/>
    <dbReference type="EnsemblBacteria" id="ABX04091">
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1447"/>
    <dbReference type="eggNOG" id="COG2814">
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-1469-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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            <end position="42"/>
        </location>
    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="246"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="45812" checksum="8EF08C44AD61518A" modified="2008-01-15" version="1">MNKLDTNNDAQASTKLARSLGWTLVIKLLISLHVGVGDFLLPLYVQALGGSPQVIGNLVGLGAAFGVFARLSLSWLADRGIIGILLRLSLAALASGFAIWSFADSSVWLMPGQALLAIGRAGSTICLSLLIAQLTSQGQRGSGYGRLTMASSLATIVGAIIAGIGFIGWDAETRQQLQQFTWLQTSLNYLPNPIPRVELFHGIYIVFSSSVVVAGIFSLRSWPHAIPAKRGTIQAIWRSVLRQPTIRSLLLVQSCISAGYSASIPMTVPLLTDRFGASVAAVAVAYIVPGIIYALFPARLGRVADRIGYRRAAKLGLGVSMLVYLAIPISPQLAITAAFWAFEALAWSFYVPALEALLAESVIPQQRGTALAIYGASGALTATVAAPLGARLYSHWIAAPFLFSALCLGMAAMFAARTPPTNADYATIKSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E1</accession>
    <name>A9B3E1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1460"/>
    <dbReference type="EnsemblBacteria" id="ABX04104">
        <property type="protein sequence ID" value="ABX04104"/>
        <property type="gene ID" value="Haur_1460"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1460"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_4_0_0"/>
    <dbReference type="OMA" id="IWLYGGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1482-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="21392" checksum="17582D7C722E66BD" modified="2008-01-15" version="1">MRQLIYFIACTADGFIAREDGSFDFFPMQGGHMQYLQQEYPETIPSHLHALLGITAEPRHFDTVVMGRHTYAVGLSEGVTSPYAHLRQYVVSQSITTSPSPDVTLVANDPVDLVRRLKQEPGQNIWLCGGGSLASALIGEIDQLILKVNPVILGQGIRLFDRLDAPVQLELLEQQTFDGGVALHRYAVAHHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E4</accession>
    <name>A9B3E4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transferase hexapeptide repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1463</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1463"/>
    <dbReference type="EnsemblBacteria" id="ABX04107">
        <property type="protein sequence ID" value="ABX04107"/>
        <property type="gene ID" value="Haur_1463"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1463"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_3_0_0"/>
    <dbReference type="OMA" id="YHIHIGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1485-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="4">
        <location>
            <begin position="6"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="192" mass="20834" checksum="2545E0D6FA413C8A" modified="2008-01-15" version="1">MSKTEREKMLAGELYSAFDPELQALSLRSRRLSRQFHAIEPGQPEQSRALLGEWFGHIGENVWIEPPFFCDYGAHIRLGNNVFFNANCVILDCNYITIGDNTMCGPAVQIYAASHPLIASERIKGPELGFPVTIGKNVWIGGGSIICPGVTIGDNTTIGAGSVVTKDIPANVFAAGNPCRVIRELTDPSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3J6</accession>
    <name>A9B3J6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2930"/>
    <dbReference type="EnsemblBacteria" id="ABX05568">
        <property type="protein sequence ID" value="ABX05568"/>
        <property type="gene ID" value="Haur_2930"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2930"/>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1018514_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2962-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30114" checksum="75ADCF62C2031E31" modified="2008-01-15" version="1">MHIPILSRISTKITLASAFLLFATILLVVIGLLRGFAQTRTDVTTASQHGLQNQGQVALFDLTQVEAKLLNANLEQAASTTRHLVSLFNSLDQVPSLSLDDPLSQLTTGPANNRFDANPDRKSDLVIFANTPDSALLRQNLRDSQILDAIFPGVLANLGDALAIYYVSNEGMTRYYPVSNLQDIVPSDFDVPNENFYTIVAATRNPERKTVWTDIYSDELGKGLLTTVSSPIYQGDQFRGFIGIDITLNEFLKQLDTIPRPVAMLLCLINRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B486</accession>
    <name>A9B486_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
            <ecNumber evidence="6">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4989"/>
    <dbReference type="EnsemblBacteria" id="ABX07619">
        <property type="protein sequence ID" value="ABX07619"/>
        <property type="gene ID" value="Haur_4989"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4989"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_4_0"/>
    <dbReference type="OMA" id="QSNMKRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5052-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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        </location>
    </feature>
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    </feature>
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    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="354"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="148"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="565" mass="61566" checksum="4F2BBE7F76FCE9F4" modified="2008-01-15" version="1">MLNEFIKFSDWSITTLIALSPLVGMLLALVFPKPAENSRTIAWGVFAWSLVPLGLTLFLWLSGGFNPALASVAGDQAMIQQVDRVRWVPFFNADYFVGLDGLNFPLVFLTTALTPVCILAAFRIKHRQNVYLALMLLLESAMLGYFVSLNFLLLFLFWEFSLVPMFFIINNWGGENRRYAAFKFFVYTMAGSVAMLLIFEFIYLATGTFDLVVLSRLGQGLPVDPALLAPKLGAGYTSGATLQSMLFSAVEDIGLTSILGTSNGTPAAIVFWSIFVAFAVKLAVWPLHTWQPDTYENAPTSGSMIVSAVMSKMGAYGMIRIMIMLFPQQTKFFAPALAILALASILFGAYAGLAQINLKRLIAYASINHMGYVLLGLAAVASAAPESLGDLAVNIRASAMNGVQAQMVAHGFSTAALFFLAGELYERTGTYQLDQFGGLRKVMPIFAGIMGVAMFANLGLPGLAGFVGEFFIFRGAWGTQPVITTIAVLGLIVTALVLIRMYQKIFYGPVNHKLTNLPDIKVGDWAFNVTLPLIIVLLVFGIFPKPLMDLSNYAATVMAQVFTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B487</accession>
    <name>A9B487_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
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        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="6 7">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4990"/>
    <dbReference type="EnsemblBacteria" id="ABX07620">
        <property type="protein sequence ID" value="ABX07620"/>
        <property type="gene ID" value="Haur_4990"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4990"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_2_0"/>
    <dbReference type="OMA" id="RIACSSV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5053-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="241"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="417"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="142"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="504" mass="55150" checksum="5CEE5BB01EB8BECE" modified="2008-01-15" version="1">MHLIESLPAGIPYLSLIWLIPLLGALVIMFLPKEQKQAMRIISAVVATISFGIALLVFFAYDPNATGYMGTKMQFVEKLDWVPQLGMSYLVGADGISLPLIVLNGLVIFTGTFISWNIEDRVKEYFVLLLLLVVGVYGVFMALDLFLMFVFYELAVLPMYLLIGIWGSTRKEYGAMKLTIYLMVGSAALMIGMVAIYVVGGTFNMVELSQRVFSLEFQKIFFLPVFVGFAVLAGMFPFHTWSPTGHVAAPTAVSMLHAGVLMKLGAYGALRAALWLMPNGAQFWLPGIAVMTLMNVVYGASIAMVQKDFKYVIGYSSVSHMGLVMLALASMNETALNGAVMQMFAHGVMTALFFAVVGRMVYERTHTRQLPELGGLMKVMPFAFVVFIIASLSSMGMPGTAGFMAEFTIFTGVMNQYPLVAAVAALSIPITAAYVLRVGYMAFMGEVKDPHYHDLPPLTWQEKFSGTVLAIVVIGVGLFPSIIMDYIATGVQPIAQRMIDLAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B489</accession>
    <name>A9B489_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4992</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4992"/>
    <dbReference type="EnsemblBacteria" id="ABX07622">
        <property type="protein sequence ID" value="ABX07622"/>
        <property type="gene ID" value="Haur_4992"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4992"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426853_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5055-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="641" mass="69296" checksum="64FAC1275C8D2DBC" modified="2008-01-15" version="1">MTDLTNTTLGKYTLGQPLGAGGMGAVYRSIHPQLGRSVAIKIILGNATKDARQRFLREAQVAVQLSHSNIVRVFDVDEDKGMPFIVMEMIEGPSLSDELRQGRMPLEKVLKITAELADALEYAHSQGILHRDIKPANVLIRPNGSAVLVDLGLARLADSESKEHQLTQSGMIIGTLSYMAPEQIQAQPLDARTDIYALGVLLFQMITGRLPFEGDTAQIMFGHVYTQPPAPSTTGALLPPALDGLIMAMMAKAPQNRPQSMGEIARVLRSIMNNAATPVGYENYSGPTVVRPQQPMPANYAAFPSQQSYGAAQPSQPQYGGHPSQPQYGGMPNTGNLGPTQPQYGSMPQPNPVLIGQPPRRGISPWFWLALLSIVIIGGLGVYTINAAFDEKLPPKDPDIFVQIPDLATQRPRPTIGSAATAVANRKTPTPEVVAAEPPAKTPQAADPNAEAEFTLSNIGSRKAGTTLLMYGMVTNNTDTPKSAIKIEATFLVDGKEVDFETGYGVIAVVNPGERAPWILVLSEAPEYQTIEYEVFGLNNALGSAFEYPDLKIDELEISPDGIFYEVTGKITNTGGKRTRTILIYLVTYNEKDEIIGVDTITPGNSTLSPDATARFEGSVLFSPSQYKIARYETFVRGTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A2</accession>
    <name>A9B4A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0007"/>
    <dbReference type="EnsemblBacteria" id="ABX02659">
        <property type="protein sequence ID" value="ABX02659"/>
        <property type="gene ID" value="Haur_0007"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0007"/>
    <dbReference type="HOGENOM" id="CLU_569581_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-7-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="479" mass="51329" checksum="2063AD37E64DC917" modified="2008-01-15" version="1">MSRIRASFRLAIVLLAMLFLVGPVFVARAHVSPAQTQAPATPNDTQYLWIAGSSFQTRDSTTAFETTRNVNNQPTGCIYATSSGEFTAPVAVPNGATILGLDYYLYDTSTTQTKAELTLNDSDMVTPRELITVEISSSVGLTNTYAPMGALYAPYVVNMQTRGLFLEWFPRVTNAAMQLCGVRIAYTAPAEPRPSTDYLFIVGSTLVNTNSSTEHGYAGAGCTFVKINGRTLNADVDLPQGSQLTAVRSYFRDVNNADLTVKLIASNGQGVTNTLATLTSPVSNTAVVNADQSLNYTVNESSESLSVLADFGGVLSNQIRLCGVRFQYTNPSAKPTQDSRFITGSTFVPRRSNVSYTSDANGCVNVSNEVEDLTTNVTAPEGAKAARVTFYYKNAAAGPTLNLYSFVGSGDFTSITSVPVMGTGTQNAVNINYPIENAEKGFALVWDASSASSEYALCGAKIDFLYTQQVFLPAAMNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C5</accession>
    <name>A9B4C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0030"/>
    <dbReference type="EnsemblBacteria" id="ABX02682">
        <property type="protein sequence ID" value="ABX02682"/>
        <property type="gene ID" value="Haur_0030"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0030"/>
    <dbReference type="eggNOG" id="ENOG5030KTZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146087_0_0_0"/>
    <dbReference type="OMA" id="FWALMIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-30-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025461">
        <property type="entry name" value="ABA4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14108">
        <property type="entry name" value="DUF4281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="17285" checksum="374C25E5F452FAB3" modified="2008-01-15" version="1">MVAQLFSLSSLFVMPFWFLMVVLPFWKWTQRIIQSPWIILGPALIYAIVLLPIFATVWADVSNPTLPGVIELIGNESGATLSWVHFLAFDLFVARWIYLDSRERNIFALIISPILVSVLMVGPVGFLIYMVVRTIHGLVRSPNLTTIAQPVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H7</accession>
    <name>A9B4H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1498"/>
    <dbReference type="EnsemblBacteria" id="ABX04142">
        <property type="protein sequence ID" value="ABX04142"/>
        <property type="gene ID" value="Haur_1498"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1498"/>
    <dbReference type="HOGENOM" id="CLU_121976_2_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1520-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13901" checksum="DA4DC19DC0C0D7A9" modified="2008-01-15" version="1">MNTKSSALRQLIIAFVLFPILLMGVMLALPNLPESPWRALLAIVPLVPVGLGIQAMYRAISGLDEFQRHIQLLALAFAVGATSFLTCGYGLLQVLVDLPQLSWLWILPLLTTCWSFGLAFANRSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q4</accession>
    <name>A9B4Q4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1576"/>
    <dbReference type="EnsemblBacteria" id="ABX04219">
        <property type="protein sequence ID" value="ABX04219"/>
        <property type="gene ID" value="Haur_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1576"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_818088_0_0_0"/>
    <dbReference type="OMA" id="DHILENY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1600-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="30567" checksum="1B53EC5DF7AD5212" modified="2008-01-15" version="1">MSEELIFTHSEDGVGLAGVIFQLRSRSHEGLVCIWIHGNFGRFYNIASVTIGRNLGLANYPMISANTRGHDITNLIWKAGKAVAGGSSRELLTESPYDIGGWINFASANGFQRVVLIGHSLGAAKLIYYQAQRHDPRVVGLVLASPGVRSQVSSEQLELAQAMVDRGQGDDLLPPAHGAAIWNRLSAASLLNRHATLPLIYSDAHEQSYLSQLACPILAFYGAREAQAGTGSDTELALLKQWCRASPRVDTQIIAHADHGYAGCEPAIAQVIAQWISSIQGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S9</accession>
    <name>A9B4S9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3014"/>
    <dbReference type="EnsemblBacteria" id="ABX05652">
        <property type="protein sequence ID" value="ABX05652"/>
        <property type="gene ID" value="Haur_3014"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3014"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_3_0"/>
    <dbReference type="OMA" id="LAIVECW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3046-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="62"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="29288" checksum="AC929013509F0D27" modified="2008-01-15" version="1">MMFGYHGRANKRSLTKNAINLTWLIAFLFAQKSPLTVKLGLVILLIERSIKFLGYGMTDEQRERREAILEAARAEFAEKGFRGATIKSIAARAKIQSPALIYWYFPNKDALLEAVMQGQLPLLQQMQSLDGLFDQQPRQLLGMLAKGYLQAGDNPHTVQMMRVLLGEMLLGRNPTELLNQQIVPQIKQFLERYLVHQIQLGRMRQHDTRASTRAFLGMLMPQMLSKVILPSLQADGLTDDEHIATVIDIFLNGLKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4U8</accession>
    <name>A9B4U8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3033</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3033"/>
    <dbReference type="EnsemblBacteria" id="ABX05671">
        <property type="protein sequence ID" value="ABX05671"/>
        <property type="gene ID" value="Haur_3033"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3033"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047537_0_0_0"/>
    <dbReference type="OMA" id="MAPEQYT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3065-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="13"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="461" mass="50466" checksum="AD94E3C6B78B789F" modified="2008-01-15" version="1">MHLVAGQQYGRYEIVDDRLAEGLSGPVYHAIINHDDGHREEVALKFLTNKLPQVRQYFMNEERLLKKAEHPHVIGFVHSNVRDEPYTLATTFVYAYSNKELSKQKSETIALQIAEQIGSALDYLHIAHPDSPVIHRDVKPDNILVDKATHDAILIDLSVASHERFALVDERGFGTPPYMAPEQYTGHEVPATDQYALALVVYYFLTGDTIPTIKPPKIKGMESNDPQVYQAALAIWNTEFRQQLAAQNERIRKNLAKHPTAIEVFLKATAFEPHDRYSSCAAFSMAMHEALRNDGAAFAAPSMPISNSRRSTMISIGAIGALVLIAVLFLVLGGGDTPDVNGKATPEQAAMQPTSTLPETPTTGGIPTVTIEAGIPTSTLPPIVSPTTGGREVTLSQGYILRAQPGDGSANALGSGQALEGQKFRVLDENPSTISGDRRKWFNVQRINGGETGWLPETVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4U9</accession>
    <name>A9B4U9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3034"/>
    <dbReference type="EnsemblBacteria" id="ABX05672">
        <property type="protein sequence ID" value="ABX05672"/>
        <property type="gene ID" value="Haur_3034"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3034"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_516564_0_0_0"/>
    <dbReference type="OMA" id="YGRLYIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3066-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="59"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="527" mass="55537" checksum="D19B33E4BD1EEC59" modified="2008-01-15" version="1">MSQAANLPNLVVYGQSDVGRQRNNNEDNLAWRHADERSVGTKLVNGVTELFAKIRGGGATGFSVKIDHKLLASHGRLYVVADGVGGNDDGELASRAVVEYTTKFFYNSDPKNYKSKQDQLNAAIQYATKMVYKEAGNTNRASTLVLALVWDEGTFRKIIFSNVGDSKGYLFRANNTEYDRAVQTKDHVNAMNKSLWQSMGDPEVTPHFSDELVLGKDDVIVLCSDGLSDGVQAEEIGKIATRNAPQNATTELISLANERGGHDNITNVVVRNGPAPIQWGALGGILGVVLLVAALLGGIVFIGGDDVNRTQGGRNAIMIPTRPIITMVDGSFATVTLPAETATAEAELIRQATENPVPTDTLGPQATSVPGTNPTARPAATATNRPAANNPTPIPATNPPAVQPTNPPVVIQPTNPPAPGDRDGDGVTDDVDPCPDVAGPNNGCPAPVEPTAPPAVVDTDGDTIPDNVDDCPNEPGDPSRNGCPKPVEQATNTPKPPTDTPRPTDTPQPTAVPTSPINPNDPPTPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X1</accession>
    <name>A9B4X1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PGAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3056"/>
    <dbReference type="EnsemblBacteria" id="ABX05694">
        <property type="protein sequence ID" value="ABX05694"/>
        <property type="gene ID" value="Haur_3056"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3056"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560002_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3088-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="487" mass="53191" checksum="C73B151BEBBB68FA" modified="2008-01-15" version="1">MPNNQVRLDGSSQAHEVAPNYRIIAQGITGNAAVPSQEPRRGEAGAGVIKGLDLALITTESKLAQTFTLDLESSLPPPPGAMRGSSDFVLQTPDFGTNTAQAVLYTDQATGYSQWIFPEPSPNPATQRRGGASVTYRLPREPIVPLPPAPGEDARRGGVIKAIRKVVRVIAWKTDELIGNTLEAIISKWESVKRAYGWQNLPLNDTNPVDWARIQTGRSLLLIHGTFSSATGAFAALPNETIGRLQQIYNGRLCAFNHPSLSVSPQANIDELLKTMPNNLEIDVVTHSRGGLVGRELLSRVQQGIPLRVRKMIMVACPNRGTPLADGEHWLTMLDRYTSLLADLPDTSASVIMEGILTVVKLIGHAGLRKLPGLAAMTPKNSYLQQLNAGQPGQTQVYAMVADYQPNDPNWIKRFMRQQGNKLIDHFFGEANDGVVPTAGGYQGNSDGSGWSIPSERRILFDTDKRINHSSFFGNQAVNQQLVEWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X5</accession>
    <name>A9B4X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3060"/>
    <dbReference type="EnsemblBacteria" id="ABX05698">
        <property type="protein sequence ID" value="ABX05698"/>
        <property type="gene ID" value="Haur_3060"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3060"/>
    <dbReference type="HOGENOM" id="CLU_1832420_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3092-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="16325" checksum="9C3483E6C5B2AAF8" modified="2008-01-15" version="1">MILQEFARYHSHYFFDPDDAILAPLKISNPRAIDGLICMLPGSAVVFYRTPRGLFLRLNRRELQIGDATSADVIRGETNTLIVYEHVYERLRWSYTPPAWIAPLVPNEHASLDEEHFDFGVFIYNVLSNKQRKRLVFSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y7</accession>
    <name>A9B4Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3072"/>
    <dbReference type="EnsemblBacteria" id="ABX05710">
        <property type="protein sequence ID" value="ABX05710"/>
        <property type="gene ID" value="Haur_3072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3072"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_0"/>
    <dbReference type="OMA" id="HLECSYR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3104-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="456" mass="50834" checksum="1402C0F36F5BF85E" modified="2008-01-15" version="1">MTVQQMLWKSGPTDAPLPPVADGSFLVGSLQAMLSDPIDFFVKQYQKFGPIFRVKALNNKFTILAGPEACLFLAREGTKHFSSWETWHSMDAEMGASKSLISVDGEQHSRLRALQKRGYSRQTIETQFPEVLKVVHGFLDQWQVGTSKATVTQLQRLITDELGMLIAGQGPGDYIDDVRTFVRIALMTHITRQRPSILRMLPEYRRARDRSLELSKQVLKAHRSGTRDANRPPSLIDDIIAATNDPSLMPEGDLVMTALGPYIAGLDTVANTMAFLLYVLTTKPELYEQVEAEADALFANGVPDPADLRKMEVLHRVVLENFRMYPIAPAVPRTVKAPFEFGGYRVDAGTRTLVATTVGHFLPELHPEPEKFDIDRYLAPRNEHRIPGAFAPFSTGSHTCLGAGLAEVQIMLTTAALLHYAKFEADPIDYKLKKVFAPTPAPDSSFKLRLVTRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B520</accession>
    <name>A9B520_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multi-sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3521</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
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        <location>
            <begin position="6"/>
            <end position="26"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H9</accession>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </dbReference>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-155-MON"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="11663" checksum="1892E82D3EA2B979" modified="2008-01-15" version="1">MVKQKILSTFSNITKVRAQVEAYRQKFQDLRPWWPVLIPFLLWRGKRAYDQEMKNVGIKLGEAALQKAQEQHKLQEQQAKLIETQEKINQRSNKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R6</accession>
    <name>A9B5R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
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        <name evidence="2" type="ordered locus">Haur_1656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1656"/>
    <dbReference type="EnsemblBacteria" id="ABX04299">
        <property type="protein sequence ID" value="ABX04299"/>
        <property type="gene ID" value="Haur_1656"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1656"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077728_1_1_0"/>
    <dbReference type="OMA" id="YRSAGWT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1680-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="19320" checksum="1C6C7ECD957B8432" modified="2008-01-15" version="1">MISIQAYNFNQAQAKIDQLCHLLIDSVGQGASIGFLPPLSQAEVTAYWQAIIGDLQTEQRILLVALQDDQIVGSVQLDLPSKANASHRAEVQKLLVHSQFQRRGIAQQLMNALEIHAQAQGRWLLVLDTRQGDKAEPLYRKLGYQAAGAIPNFAQSADGTTHATIFFYRELAPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X7</accession>
    <name>A9B5X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3133"/>
    <dbReference type="EnsemblBacteria" id="ABX05770">
        <property type="protein sequence ID" value="ABX05770"/>
        <property type="gene ID" value="Haur_3133"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3133"/>
    <dbReference type="eggNOG" id="COG1134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_101_1_0"/>
    <dbReference type="OMA" id="IDRYVYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3165-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="48061" checksum="22092CBE7ABBEC41" modified="2008-01-15" version="1">MIIFENVSKHFTIKRDRRNSIQERIAGLFKPQVLPDEDFWALRDVSFTINRGETVGLIGHNGSGKSTTLKLITRILQPNSGKVIVDGRVSALLELGSGFHPDLTGRENIFLNGSLLGFNRAEMAEKVPAIIRFSEMQEFIDMPVKHYSSGMYMRLGFAVAINVDPDILITDEVLAVGDELFQRKCLDRIYQLKRRGKTILFVSHALGQVRDLCDRALWFHHGNLMTDSTPTETIDNYLAETNQRDAERIEAEKAAENPEPEAPSTEIETKTEEEIEFDARRWGSREAEIYNVELLNAAGEVIQTATTGQALTIRMHYQAHQPIEKPVFGVAIHHRTGFHINGPNSRFAGLEIPQIAEQGYVDYQIENLPLLEGNYELSVALYDHTLTHPYDHHDRKHNLRVYAASIGEQFGTIYIPSQWSWHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B645</accession>
    <name>A9B645_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06256">
        <property type="protein sequence ID" value="ABX06256"/>
        <property type="gene ID" value="Haur_3620"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3620"/>
    <dbReference type="HOGENOM" id="CLU_2569165_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3659-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="9110" checksum="B05803E2DF9E38A5" modified="2008-01-15" version="1">MALFWVLLIAIERLLTIFNEFDYPNNAQPEHLTKIARNQQTSVRPASKILTAIGTSNFSRVMAGLQLNQSVLDGTFGLNCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B680</accession>
    <name>A9B680_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3655"/>
    <dbReference type="EnsemblBacteria" id="ABX06291">
        <property type="protein sequence ID" value="ABX06291"/>
        <property type="gene ID" value="Haur_3655"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3655"/>
    <dbReference type="HOGENOM" id="CLU_833592_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3694-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="348" mass="40110" checksum="F28AFA7AF7554296" modified="2008-01-15" version="1">MMNCPNCYTKIPDNQATCERCGWPDLAEKTELKPATPRSKQAPSMPMTGKQRWYHFIKALFPLLFALVPIIGIFTLVSPKNFTLIPLLIVIGLIVAATYFNKDLHDLVNSVVYVESDQLLKVDRFYGHKGSIIYMAFFKRLGDFQVDQEIYNTVELQSFYRVMYSQKSKKLWKVKLESNQAVLDNVLSEKQISYSPNEGVQGVGQLSLNQRKEIIVSIVNFVIFMILIYLFLGSYIKRLLWNSDNASIGIIVSSVILFIFLNLFKGIVFQVIDFITGKVESTIDTFIDFDKRHSNPGVEYTAKFQKLGKVSVKQQHYLELVKGEKYQLFYSRWSKIVWDVQKINEKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U6</accession>
    <name>A9B6U6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11 12">Xylose isomerase</fullName>
            <ecNumber evidence="4 11 12">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xylA</name>
        <name evidence="15" type="ordered locus">Haur_1762</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11 13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4 11 12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1762"/>
    <dbReference type="EnsemblBacteria" id="ABX04405">
        <property type="protein sequence ID" value="ABX04405"/>
        <property type="gene ID" value="Haur_1762"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1762"/>
    <dbReference type="eggNOG" id="COG2115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060750_0_0_0"/>
    <dbReference type="OMA" id="HKFTFGL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00455">
        <property type="entry name" value="Xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013453">
        <property type="entry name" value="XylA_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02631">
        <property type="entry name" value="xylA_Arthro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="14">
        <location>
            <begin position="40"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX04405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="42442" checksum="AC920EFAE7FCC6EE" modified="2008-01-15" version="1">MYDAQPAHKFTFGLWTVGNVGRDPFGEPVRKPLSPPEIVHLLAEVGAWGVNFHDNDLIPIDATPSERDSIIKAFRGALAETGLVVPMATTNLFSHPAFKDGAFTSNDPAVRAYALQKTMAAMDLGAEFGATTYVFWGGREGSESDAAKNPLEGLKWFREALNFLCEYSLAQGYNYRFALEAKPNEPRGDIFLPTTGAMLGFIETLDHSAMVGVNPEVAHETMAGLNFAHAVAQALDAGKLFHIDLNDQASGRYDQDFRFAAHNYKQNFFLVKLLEDVGYDGPRHFDAHAYRSEDLQGVKDFARGCIRSYLILAEKARRFNADAEIQGLLAELKTVEPAVAALAGSYSPERVAALKAHEFDRTGLGARGLGYEKLDQLTFELLMGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B728</accession>
    <name>A9B728_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05896">
        <property type="protein sequence ID" value="ABX05896"/>
        <property type="gene ID" value="Haur_3259"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3259"/>
    <dbReference type="HOGENOM" id="CLU_543778_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3294-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734599" evidence="1">
        <location>
            <begin position="22"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="2">
        <location>
            <begin position="195"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="501" mass="52120" checksum="8344B11D203B89A1" modified="2008-01-15" version="1">MRRLSIMMLLASLLVACGGGASEPTAQSSEPTSAAATAAATNTPDNTVATVDASAANTSFASAAPLDGQIKASVNQSNLYYRLDVPVGGVVTSTIKVDGQSPQGLSAVLYDKNQSFLKSINLAPGETGMLGYQFGLPNGGQVVWEISGNALFSLTGSAAEQADAGSKGDAGDDFGQAVNAKLGTLAGSLGDADMTDYFSLDVPEKGGTLTIDAKTNGDVQLQLFDETQNYLNNASVSANTPVSLNRILNSEQGGRWFVRVDGTGSYDLSLDFAAQTDGSSAGDAPDEIDRAVKVEVGTITGMLGGDDRGDIFSVEVPQTGFAYTLTASTKQGSLTIQTLDNSQNYVDQADFTSDAPVAVGRTLPGERGPRWFVKVLGEGEYQLELVTIAQNDAGSSKDAGDEIPAAVVVAASPIEGRIGNDDRDDYLRIPASLGRKISVTVIGDGLIDVQLYNQERNYAESAKSIIAGSPASLNAPEGDGDYYLQITNGDSAVNYRIEIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D8</accession>
    <name>A9B7D8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate dehydrogenase</fullName>
            <ecNumber evidence="5">1.3.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.99.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3785"/>
    <dbReference type="EnsemblBacteria" id="ABX06421">
        <property type="protein sequence ID" value="ABX06421"/>
        <property type="gene ID" value="Haur_3785"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3785"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_6_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3827-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="5"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="4">
        <location>
            <begin position="447"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="499" mass="52530" checksum="E6CAD24721FF49A6" modified="2008-01-15" version="1">MIQHDVIVVGSGIAGMRCALEIKRNAPKADVAIVTKQYPVRAASVVERTGIAAALGNSSSDSVEAHISDTLAYGKSNNAAAVKALCEQAPAAVYELEHMGLPFSRLKSGRIAQQVGYGHSQPRLANAGDQTGHAIVTTLYGEVVRFGIKVYPEWFMLGLVVEGKNVRGVSVLDIRSSEIEVINAKVTVLATGSYGQLYATSSDSYASTGDGHAAALRAGINLIGMDLVNFHPLGVANTGLIINEQVLADGAHLLNASEKRFTNEQASLAEVTAAVNAEIAAGRGVDGHVWLDVRHLPTSQIRERYPHLLDYAEDFAGVNPNHDFIPVKPTQQSSLGGLPTDLNGSVAGFEGLYAVGACANNGVHGEQALPGNELAAAVVFAKLAGAAIADKLGAASYGNVPSYATSNASDEIEGLFGQKGSHKLGLVRKNLRQAFNSQAHTAASDEQHVGLVHSLREQFGQIALHDKNRRFNTELLEALELDRLLDVADAVAKASVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7G8</accession>
    <name>A9B7G8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0289"/>
    <dbReference type="EnsemblBacteria" id="ABX02941">
        <property type="protein sequence ID" value="ABX02941"/>
        <property type="gene ID" value="Haur_0289"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0289"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_1_0"/>
    <dbReference type="OMA" id="DRGHEDH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-292-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="7"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="703" mass="77045" checksum="034078E3890BDF56" modified="2008-01-15" version="1">MKEYGPDRIHTIGLFGHGGAGKTTLAEALLFASKALPRMGRVEDGSTVSDYDPDEVKRHASINLSVIPIEWNGNKFNFIDVPGYADFRGEAAAALRVIDGMVLVLDAAGGVEVGAELLWQMAREANIPRVVFINKLDRENANFQRTVEQAKGLLSEAITPVHMPIGSGANFKGIVSLRKRKAWLHHNGKDGAYEIAEIPAEIRQEALQMADGLIEKIAMTNDHLIEEYLEGGADALSAEEIRQGFQAAINAHTIMPLFIGSATTLSGIPQLLDGILDAIPSAANRLTTAHDLRNDDDYFLEGKADEPLSALVFKTLVDQYVGRLSFFRVFSGEIHSNSVVRNARTGREERIGQLFQMRGKEQTPVSSVSAGDLGAVAKLADTLSGDTLYNPENPLRLRSVSYPEAAFTAKVTPHSKNDLDKLGNALHRIVEEDPTLHLGRDIQTGETLLAGLSETHLNFVAERVKRKFDVHFDLAIPSVPYRERISSTATATYRHKKQTGGAGQFAEISLRLEPLPTDPNRADPLEFVSEIVGGVVSRSFWPAIEKGIRESMALGVLSGHPVIDVKAAIYDGKEHPVDSKEIAFKTAGKFAFREAARKANPVIIEPIYALKINVPDEYVGDILSDLNGNKRGRVQGMEQIGHSRTLITAHVPLAECQRYATDLRSITQGRGDFVMRLDHYDDVPHSVAQTIIANSKQQHDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M2</accession>
    <name>A9B7M2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proprotein convertase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0343"/>
    <dbReference type="EnsemblBacteria" id="ABX02995">
        <property type="protein sequence ID" value="ABX02995"/>
        <property type="gene ID" value="Haur_0343"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0343"/>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_397287_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-346-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P/Homo B" evidence="4">
        <location>
            <begin position="296"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="631"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="730" mass="78237" checksum="0D6664B67ED09EE9" modified="2008-01-15" version="1">MRLRIGLIITLLLMITVGKTLQNPRDVAQALSQTPDQTTIPQGFSRIQEQEFNDLPLNANLLVGSSLVVRGSIQQTDVDYFALDLTAGQRLAMATITSASVASSDTTIHLYAFDGVNSDLIETDLSDGILSNSSSVISSQPITLTGTYLIKVEGGTATTVIQPYDLYVRVLSETASEQEPNDEVAQTIDAQAAISGVVSTTNDLDRYQFNVNPGDTIFATVDFDPERDGITWNGFLDIGMINNTYLRANDSNSVSPNAEANVITVQQAGTYEIRIGSLLEIGVDASYLAQVTIIPAAIQANCQTVMSSGAPQNIGPQAGIIQSTLTVTQAANIADIDVLLNLEHSFMPDLDVTLTAPDGNVINLFTDIGNVQQPTVNLVIDQQAALPLGTYNVLSGTHFGPKWNSSLDWLAGQQAQGQWILTIYDDTDQNAGVLNGWGLRICGMPTPSDCPVGMSRSVLYSSQFEADNGGLTPGPFDQEWVWGNRNSPPIVGAYSGENSWNTNLTGNYPNSTRMQLLSPQIDLTNVTGPIYASWYQRYQLDNSVNDFYQVTAHKPQVEQILFRHQSAAMQINLGNPLVTLDQSTGWGLQRHDLSDFAGTSLYLTWDFGSDEVASFAGIALDDVEITGCIDPAQITPTNTPTPSNTPTLTSTPSNTPTPSNTPTATATPTQTLTPTETPTPSNTPTATATPTQTETPTATETPSITPTSTPSVTADPSLIPVYLPLVSKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D0</accession>
    <name>A9B8D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic amino acid hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3847"/>
    <dbReference type="EnsemblBacteria" id="ABX06483">
        <property type="protein sequence ID" value="ABX06483"/>
        <property type="gene ID" value="Haur_3847"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3847"/>
    <dbReference type="eggNOG" id="COG3186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023198_1_0_0"/>
    <dbReference type="OMA" id="KQFPVAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3890-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016714">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="PTHR11473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="SSF56534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BH4_AAA_HYDROXYL_2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="28431" checksum="864C9BB994EDC746" modified="2008-01-15" version="1">MATASPTLSRLEYPQEDHDTWAALWQRQMPLAQQHACKLFLEGIDILNLDRTHLPDPLAVSDYLNTLTGWALGDAQNAYLGPTEWFEHIAERRFPVTNYIRRPHELEFTPLPDLFHEYFGHLPAFTNREFADIAQLFGPLYLSAKDERQQLGIARIWWFSTEFGLLRENGELKVLGAGLLSSPGELLHALNPETPRYEFDIERVADTASAPYGYHEHYFILNSLDHLRSIVYEYAELEGLPKPQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S6</accession>
    <name>A9B8S6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07740">
        <property type="protein sequence ID" value="ABX07740"/>
        <property type="gene ID" value="Haur_5112"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5112"/>
    <dbReference type="HOGENOM" id="CLU_651768_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5174-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="421" mass="43336" checksum="B9927C07A543049A" modified="2008-01-15" version="1">MTSPYDHEFQAFVAPLLAGLSVAGRHAELDRLTDLWQREGAVPVNGQLVWLGTPSTTRPTATPPAATAPRGAPRWLGLVIIAVVLLGWGLLGRRSQAAPLAEGVLRPVTVAVDGEAAPVQLVIGSQAFPVHAFDPALGWPDPVGIPAGTAVWGGTRSQVVLGLDGAAFAADALAVGSTLTLQQAQGDPRTLTVVARQTVAVHAGSAIPQQQVGVTLVLWDQDDLSTRTLVQALPSEQPVLTTYNATLPLAVTGMDWTLVAMQPTLMVSVTVGPTERSGVVSRAGVALVSLPLATATTITLPVTATAMPGTRVDLALTIDGQAVPLSIAMPDAPTLTVDWQTVTATPQGLAITTVLHSPATVLTPADATCTAGGVTHALQPNLPWPLVITTAHAVVWTCPHDPAQPVPVTVQLGSVGQSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X9</accession>
    <name>A9B8X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_5165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="6 7">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6 7">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07793">
        <property type="protein sequence ID" value="ABX07793"/>
        <property type="gene ID" value="Haur_5165"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5165"/>
    <dbReference type="HOGENOM" id="CLU_027562_9_5_0"/>
    <dbReference type="OMA" id="TLERDWV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5227-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0614">Plasmid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="99"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="33382" checksum="F995C3EC7962BEBE" modified="2008-01-15" version="1">MTTPLRQRMIDDMQIRGLSAQTQSAYVQAVRQLAQYFNTPPDRLSDDQLRRYFLYLRTEKQVSASTITVTLCAIRFLYQHTLQRSWPLLDALRPPKAQPLPVVLSRDEVRAILHQVRTPRHRVCLSIIYACGLRLMEGVRLQVCNIDSARLMLHIQHGKGNKDRYIPLPPPALAMLRAHWRSHQHPRWLFPSHWVDKALPIAARSVSMSRDGVQRAFLLACQASGMRKHATVHTLRHSWATHLLEAGVNLRIIQGWLGHTSPTTTAHYTHLTQHAESSAAITSQRLFEELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y3</accession>
    <name>A9B8Y3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07797">
        <property type="protein sequence ID" value="ABX07797"/>
        <property type="gene ID" value="Haur_5169"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5169"/>
    <dbReference type="HOGENOM" id="CLU_2246251_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5231-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="104" mass="11964" checksum="83514CAE3EABE037" modified="2008-01-15" version="1">MGRWTPPPWWLWMLVQVSAWFFGMVGVVWCTLMLISLYHDTRSWPPDDLLSRVVVAFGWSCLSIGVDGWIILRGTQTRWRGLVGYGVLLLANGALIYTFGRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B922</accession>
    <name>A9B922_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_5209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="9 10">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="9 10">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07836">
        <property type="protein sequence ID" value="ABX07836"/>
        <property type="gene ID" value="Haur_5209"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5209"/>
    <dbReference type="HOGENOM" id="CLU_018204_3_5_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5271-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0614">Plasmid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="126"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="44219" checksum="83B4309671A1FFAD" modified="2008-01-15" version="1">MLFDKPMPYWNDHHQRLQQEIRTFVEHVATPIWHSRLPHDERFPWAARVAAAKVGLTGIDLSPAYGGRNADFVSQGIAFEECGRLDIDARELIGSGHGAIIARHGSPDLKEHWLPRIIRGEALIGVGITEEEAGSDIRSMKTMISSNGNCYAVHGKKSYISRINEAAAFIIFGKTHPDDTHLSAILVDTQNNPAIERTEIPTMGVRGWSYGSITIHDDCVPKENMLGVIDEGFSIFEEHFSNWRIFMALLCLGAAAASMHEVIAYSQTRYSFNSPIAKFQSIMFAIAESMSAIYTARLLCYQSLWLKDNGYDNATEAAMSKLVAVKIAFDAVNGALQIMGARGYTNQYFFEKRLRDIRGFMIADGTNEIMKSIISKDIFGKDMYNTMIGRGRKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B948</accession>
    <name>A9B948_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5235"/>
    <dbReference type="EnsemblBacteria" id="ABX07862">
        <property type="protein sequence ID" value="ABX07862"/>
        <property type="gene ID" value="Haur_5235"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5235"/>
    <dbReference type="HOGENOM" id="CLU_1439275_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5297-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="21148" checksum="B9621841A1010D81" modified="2008-01-15" version="1">MKFRAPQQRIRLPARHPTVILTRVVMGIIIVTAVSLGWRLVHQPGPLVVPHQTATRTAPAAGYRLYTWTGGLQVLLVLDGPGVEDRCEVRWHNQIQVYHCWIVFDDETVLRWMLWSGDGRRGWVEADGQRYALPDTGTVMRIRANGAHGVITMLDRALPKIAAGTETKTIAAWMARDPELAPLATRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B995</accession>
    <name>A9B995_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5282"/>
    <dbReference type="EnsemblBacteria" id="ABX07909">
        <property type="protein sequence ID" value="ABX07909"/>
        <property type="gene ID" value="Haur_5282"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5282"/>
    <dbReference type="HOGENOM" id="CLU_2142437_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5344-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12316" checksum="0A7C6D20773C82D9" modified="2008-01-15" version="1">MSNDAQIVTLYQTIAALDDQIANLNTEREQARTILSSLVEAQGGKVVLEGIATMEITRPTMVASYDRAGLEDLVRKLVANGRGGIAEMIEKQRKQHHRAGSLRIIKVKGNCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A0</accession>
    <name>A9B9A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5287"/>
    <dbReference type="EnsemblBacteria" id="ABX07914">
        <property type="protein sequence ID" value="ABX07914"/>
        <property type="gene ID" value="Haur_5287"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5287"/>
    <dbReference type="HOGENOM" id="CLU_1364646_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5349-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="22283" checksum="DFA40DE8DD2FC31D" modified="2008-01-15" version="1">MTYHIPTALPPRPHIHPVVWFPWFGGLLSICFGIYRFNTLVPPYTGSITSLRLVPKGFLAFGATILCIILVVVSVVTFWTRYRRNTWRIMTGLLIGIAMLFFWIAVNIPHHLPWFIESPLYQRNPAWIQAAESSPWLILGGAGSLLGASFLILVMRLVGKKDEHGSVKPDAQQASNVATVIIYDRPPLSSTANDNSEGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE2</accession>
    <name>A9AUE2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0410"/>
    <dbReference type="EnsemblBacteria" id="ABX03061">
        <property type="protein sequence ID" value="ABX03061"/>
        <property type="gene ID" value="Haur_0410"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0410"/>
    <dbReference type="HOGENOM" id="CLU_3310918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-413-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="39" mass="4551" checksum="1EBC5C52B8CF903A" modified="2008-01-15" version="1">MTTLEEAQLINYLKATQFRVGLLINFGSLGKLEWKRLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUG4</accession>
    <name>A9AUG4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0432"/>
    <dbReference type="EnsemblBacteria" id="ABX03083">
        <property type="protein sequence ID" value="ABX03083"/>
        <property type="gene ID" value="Haur_0432"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0432"/>
    <dbReference type="HOGENOM" id="CLU_2508179_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-438-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="10037" checksum="E9A22748ECF500BC" modified="2008-01-15" version="1">MFAKGRVSYSTLWSDQQVDLLENMDVVVNRPYLPALVLYMRYNPDPQPHELWLYDPQMQTHTQIEYTNPDYVFNGMSQALIDPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS7</accession>
    <name>A9AUS7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1961"/>
    <dbReference type="EnsemblBacteria" id="ABX04604">
        <property type="protein sequence ID" value="ABX04604"/>
        <property type="gene ID" value="Haur_1961"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1961"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071279_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1990-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="67"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="38059" checksum="FD5F7A44ADC161F6" modified="2008-01-15" version="1">MSQPINQLPWEHADWFDRLSTWIEQQLASHQRSMLEPIQLVHQRPWSAFAQIQTNQGMVYCKAPAPAFHYEAALTQALADWQPDCNVPVLAIEPTQAWILSADAGTTLRQLGQNLTQLEHWYALLPQYSELQINLAQRVPALLALGVPDRRLSQFPTLFRELLNDRQHLLIDQELGLSSSEYQQLQALAPMVQAQAAQLAEFGLPETLTHEEIHENNVLYGERGYTFTDWSDCSVSHPFFSLLVTLRAAAHWLKLDEHGPELQRLRAAYLEPWTRFAPRSQLDQAVEIAYRLGMINRALSWRQALDGLDPAQTQEYQDNVAGWLQDYLTANTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW9</accession>
    <name>A9AUW9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein Haur_3923</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3923"/>
    <dbReference type="EnsemblBacteria" id="ABX06557">
        <property type="protein sequence ID" value="ABX06557"/>
        <property type="gene ID" value="Haur_3923"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3923"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140930_1_0_0"/>
    <dbReference type="OMA" id="MGNMMKQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3965-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="101" mass="10961" checksum="516EC0B9D1A6AB53" modified="2008-01-15" version="1">MDRKMLNQLQQMQKKLMQAQEDLGKTLVEGSAGGGVIEVKMNGHREILSITIAPEAVDPNEIEMLQDLLMLAINDASKKAEELSNAKMGPLTGGLNIPGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUX1</accession>
    <name>A9AUX1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3925"/>
    <dbReference type="EnsemblBacteria" id="ABX06559">
        <property type="protein sequence ID" value="ABX06559"/>
        <property type="gene ID" value="Haur_3925"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3925"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2046422_0_0_0"/>
    <dbReference type="OMA" id="GVAMAYH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3967-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="12208" checksum="A4BBE06E3C0C8E4B" modified="2008-01-15" version="1">MGMKDILASAIETVPGVKLAGVVGTDGLGVEMLLNDVDANFSKDIAEVELGGLAAAAAGAASRLKAGHVRDVAVETDNATYLASQIIPGYFAVLAVNGGGNLGRARFALKQLVVKLQDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV13</accession>
    <name>A9AV13_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3969"/>
    <dbReference type="EnsemblBacteria" id="ABX06601">
        <property type="protein sequence ID" value="ABX06601"/>
        <property type="gene ID" value="Haur_3969"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3969"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_16_4_0"/>
    <dbReference type="OMA" id="NFRTINA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4011-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9667" checksum="85511EF9F00F543F" modified="2008-01-15" version="1">MTTDSLTVDDIKARTRAFIGKFFKNIELQDDEDIFALGFVNSLFAMQLVMFIEKEFGIAVEDQDLNIDNFRTINAMADLVKGKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV42</accession>
    <name>A9AV42_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase_M75 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EfeM/EfeO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03120">
        <property type="protein sequence ID" value="ABX03120"/>
        <property type="gene ID" value="Haur_0469"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0469"/>
    <dbReference type="eggNOG" id="ENOG502Z9YB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_743378_0_0_0"/>
    <dbReference type="OMA" id="PVFFEDW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-475-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14656">
        <property type="entry name" value="Imelysin-like_EfeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034981">
        <property type="entry name" value="Imelysin-like_EfeO/Algp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731658" description="Peptidase_M75 domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M75" evidence="4">
        <location>
            <begin position="48"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="38070" checksum="A703DCA70C0BDBBF" modified="2008-01-15" version="1">MYRWLCALTLVAVLAGCGAETAPTTQPTQAPAAGELGAIKTYLLGKTGDLINSSTALETASQRYYDLAKAANFDYATLWSSKQAEVGTALNDAKAAWLKSSPTYEQMEGIVAGVSSLADFDVTLDAGASAEEGGDSVVNYDLTLADGRTIAKPGNLFGVTESTLWGTYDAFRVTDVEADINGNGTVEFGESLPEANVLLAAAQKLKATATELDTAAKAWEPTDTDAFSALVVMVPTMNEYFDSWKNSRFVAGDSSTQRDFVAISRLADIGDILGSLQVVYDSLSPKVAALDADQDRQIKTNLQALRDFVADVYKKEQAGQHFTAEESDLLGAEAQNRADAITGQVSQIAARLNIKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV54</accession>
    <name>A9AV54_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0481"/>
    <dbReference type="EnsemblBacteria" id="ABX03132">
        <property type="protein sequence ID" value="ABX03132"/>
        <property type="gene ID" value="Haur_0481"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0481"/>
    <dbReference type="HOGENOM" id="CLU_1145965_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-487-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="25324" checksum="5C1D83E801E163C2" modified="2008-01-15" version="1">MAAAQAPQSYQPIARPTVIPSVNTSMATPTTKPIAPTSIQLSPNSARSMLQPNRQQLLAQLQMFAYGLIGLGAVILVGLIFGLFVKGGLSGDLGGILGGGVEIGGSAIHLLLLLLATLFEAGLSNGGIIAFVVIIIILLLPAYAIFAITTGSKIAKAIILNQMPYSIKNLQIFSGIMIGFFGLIYALTNIQFKMNSNGLGGFGAEAGIGLGWGFTLSLFIMLGIFIGCIWYKNIALKLLVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF6</accession>
    <name>A9AVF6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2004"/>
    <dbReference type="EnsemblBacteria" id="ABX04647">
        <property type="protein sequence ID" value="ABX04647"/>
        <property type="gene ID" value="Haur_2004"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2004"/>
    <dbReference type="eggNOG" id="COG1600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018093_1_0_0"/>
    <dbReference type="OMA" id="YTHNYRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2033-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="450" mass="49493" checksum="DD0CC6C894B7C80C" modified="2008-01-15" version="1">MAHLQNHPTVLRFRQERAIQSTEDFPRLAATTLRDLCLDSGADDVGFVSIDRAELDNQRAEILENFPWARSLISIVCRMNREPIRSPARSVANLEFHHTVDHADDAAHTIVTALEAQGVRAANPASGFPMEVERFPGKSWIISHKPVAVAAGLGQMGIHRNVIHPRFGNFILLGTIVTDAVISAEDKPIDYNPCLECKLCVAACPVGAISPSGDFDFAACFTHNYREFMGGFNDWVETLVSSNDAGEYYERTTASETASMWQSLSFGASYKAAYCIAVCPAGDDVIAPFLTNRAGFLKEVVKPLQDKVETIYVSTETTAAYVRRRFPHKHVKRVGSGIRFSSVEAFVKSLPRVFRPTAAEGVNAVYHLVFSGAEDYAATVSIGDGPDSRKRVTITEGCVGHADLRISADSRTWLGIVAGDRTPTWALVRRKLRLRGSLRLMKVFRACFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN3</accession>
    <name>A9AVN3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4001"/>
    <dbReference type="EnsemblBacteria" id="ABX06633">
        <property type="protein sequence ID" value="ABX06633"/>
        <property type="gene ID" value="Haur_4001"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4001"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_3_0_0"/>
    <dbReference type="OMA" id="GDERMND"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4043-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="119"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="26220" checksum="0E2CBF139EB4C336" modified="2008-01-15" version="1">MREHFLHALAELEGQIRDMGNRVSLAVRDALWSLERNEPIFARQIIANDNVIDELRYQIETNALSVITRQQPMARDLRVVSMFLELASELERIGDYAEGIAELVIRCIELPALEQPPQIKTMALKAQAMLRDALDALHERDPQAAERLEHSDDEIDGLYREVLAWTFATMRSQPDYVERAMYYLWIAHNLERIADRTINIGERTSFIATGIIDKHRLRKDEADKPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX5</accession>
    <name>A9AVX5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Terminase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0565"/>
    <dbReference type="EnsemblBacteria" id="ABX03213">
        <property type="protein sequence ID" value="ABX03213"/>
        <property type="gene ID" value="Haur_0565"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0565"/>
    <dbReference type="eggNOG" id="COG3728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1188651_0_0_0"/>
    <dbReference type="OMA" id="FTEKHEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-574-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038713">
        <property type="entry name" value="Terminase_Gp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005335">
        <property type="entry name" value="Terminase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03592">
        <property type="entry name" value="Terminase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="26163" checksum="34B903B844C18196" modified="2008-01-15" version="1">MTNPEAEKPLTTRQRRFVDEYLVDFNATKAAIRAGYAERSARSIGSENLTKPNIKAEIARRADDIISKTEIVGRLAQQARTSMDDFFFIGEEERTVIKRRILVSVDKKGSSKEIVLEEVEEKAMRPATYLSLVKAEHRGVMHLIKKYSVGPKGESIELYDAQGALITLGKYHAMWVDRAEHTGRGGAPIPIDSPAMAQAADELKQWREEQCRKLSNWQSAMPTLPTSPTTTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW85</accession>
    <name>A9AW85_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2095"/>
    <dbReference type="EnsemblBacteria" id="ABX04735">
        <property type="protein sequence ID" value="ABX04735"/>
        <property type="gene ID" value="Haur_2095"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2095"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091025_0_0_0"/>
    <dbReference type="OMA" id="AGYERMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2123-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732188" evidence="1">
        <location>
            <begin position="24"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="28395" checksum="F883DED92CB06160" modified="2008-01-15" version="1">MRKLWLSLITGGFLLASCGSTVAQPNTTAPSATTTSAPSGATQPLKIVASTSWVGAFAKAAGATDITIIAPSSVQHPPDYDPKPSDLQAVADADYVLYAGFEGFAPRLQEAVGGSAERLLTVQTENSPAVIKAEVLRLSDLFGTRPHAEAFLTRFDAEYTRLSQDVRTAIGAQTPIVVSQAFVVPWVGFAGLEPAGVYGPAPLTPEELATLTKAQPRFIFENVHMGGGQPIAEATTATVINLINFPDADLDLLAVFQKNADTLKSALGTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL6</accession>
    <name>A9AWL6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">argB</name>
        <name evidence="9" type="ordered locus">Haur_4143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4143"/>
    <dbReference type="EnsemblBacteria" id="ABX06775">
        <property type="protein sequence ID" value="ABX06775"/>
        <property type="gene ID" value="Haur_4143"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4143"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053680_1_0_0"/>
    <dbReference type="OMA" id="EGLYEDW"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="40"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="25137" checksum="7EC29D9B7C0C3230" modified="2008-01-15" version="1">MRILKLGGNEIDDPTWLARLVAVIQTMVNVNDVPILVHGGGKEIGQLQVALGGEPQFVAGLRVTDQTALKAATMVLCGMVSTRLVAALNAVGVEALGLSGVDRNLVYATRLEHAAGDLGAVGKPARIRATVLYEALAADVVPVLAPLCADGVGGTLNVNADVFAGAIAAAVGADEAVFISNVPGVLVDGVVAPRLNTDDIQALIANGTISGGMIPKVESALSGLQAGVKIVRITNIDQLDAGTIIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX10</accession>
    <name>A9AX10_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2178"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04818">
        <property type="protein sequence ID" value="ABX04818"/>
        <property type="gene ID" value="Haur_2178"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2178"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036995_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2206-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735066" evidence="3">
        <location>
            <begin position="23"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="59"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="673" mass="74518" checksum="0AACD20D4AE4ED03" modified="2008-01-15" version="1">MKKLSRLIIVLGLICSIFAQHSATPKAQAAFGASDFLKANGATVRNNSGNGAIVTLKGTNLGGWLLQEGWMSPLGYPALPRTSWTASGSAGGAAAAIDGNPATRWTSNAPQANGQWFQVDLGGNQAVERVTIDAGSSTGDYPRQYQVQAFVNNAWLTVGSGSGTSQVVTVQFNNTQVTRLIRVLQTGSSGSWWSIHEFNAQIADEFNLRQALTNRFGTSTTDSLINGYQDTWIQASDLDTIKAMGLNMVRVPIHWLVLMNTNGTMKSDTESFRKLDWLISESSKRNLYVMLDLHGAPGAACPWHSCGQTGTNQLWTNPTYQNWTVQIWERLATRYRGNPTVAAYDLLNEPLLSNGAAENEQQVRQKFDFFDRLYDAVRAKDPDHMIVMAAFYDWYQALSPATYGWTNVMYQLHHYNFDTVTDWNVTNNFIQSALDKYATFTKDWNVPGFAGEYWFSTHYDLYEKFMSGLNALNVSWTNWTYKVNGGGNWGFYQNNTQAVPDLLNDSAATIADKWSRFSTNYFQPNTQFQNTVRAYAPEGSWVALQAGANNSYVSADNYGNNPLVANRPSIQGWEKFRMITNPDGTVSFMSLANNKYVAADLNNGGRLIAQSRGVLGWEKFRRVDLGNGTFGLQAIANNKYVTTDLNSGSPMLIANRDAIGGAWEAFTFVATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX11</accession>
    <name>A9AX11_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04819">
        <property type="protein sequence ID" value="ABX04819"/>
        <property type="gene ID" value="Haur_2179"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2179"/>
    <dbReference type="eggNOG" id="ENOG5032XIH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1044976_0_0_0"/>
    <dbReference type="OMA" id="MAHNITY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2207-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="30021" checksum="BEBDA14AF66415A8" modified="2008-01-15" version="1">MDRKQFLKLLGTSVATGFLVRSFEPKQAAAMGLTALQFSGTTLADWKTVLGDGLWTAPNQVPVNNADIQTDQTSTKSILRANISQRGVMAHNITYKSLIDQDLFEYIHTTSYEFRLPYIPQTNSGIQNAQTFEGGFFIWDGSQTQLDYGCAFQWVLNPWMSTFGTVYSWSSDGATQGWIPCGFLQPDTNWHQYQMMVDYHNQTCRLTIDQTSIPICFTATPKVGWGTETAARFQTEIISIWPGNTSIAPSHAVEIRNWNWNLQPYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX57</accession>
    <name>A9AX57_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2225"/>
    <dbReference type="EnsemblBacteria" id="ABX04865">
        <property type="protein sequence ID" value="ABX04865"/>
        <property type="gene ID" value="Haur_2225"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2225"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1537571_0_0_0"/>
    <dbReference type="OMA" id="HCARLEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2253-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20341" checksum="140F42F1C3E147A2" modified="2008-01-15" version="1">MREQKIVESTHSVAEIGGWLWALQDARRRTNEEIAKLSEAMIDWQPDHGDSTIGSVLYHIALIEADWLYDEVLGLDAYPEPAASLLPYPHRTKQGLLTPVLGQDLVQHCARLEQVRELLLATFNHMDLADFRRVRELAAYAVTPEWVLHHLCQHEAEHRSQIGSLRIAFERAHGIIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXD7</accession>
    <name>A9AXD7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4225"/>
    <dbReference type="EnsemblBacteria" id="ABX06857">
        <property type="protein sequence ID" value="ABX06857"/>
        <property type="gene ID" value="Haur_4225"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4225"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022870_0_0_0"/>
    <dbReference type="OMA" id="ERRTYRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4272-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="62"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="734" mass="82297" checksum="A110E4F627A215B9" modified="2008-01-15" version="1">MMKRYTLHTCIILAVALGLRLATWWLLPYNDWISDEGEYWGAAIWLAQGREFQFFDSWIWTRPPLYISFLAAHIKLFGNSALWAPRLSQALISVLSVWLTMRIAKRLTPTEHQARVSLIAGWLMALGYSFAAFSYFMLSETLFLSIFLAANLLLLRWASTRHWRDLLLAGVGFGFAALTRAIILTWLPLPALWIAWQIWRTQRPRWQAMIKPVLGFTLSVCVIVLPWTAFATNRWSNGDGLILVDTTGGYNFALGAQIATPDGRNGTRLAEILCGGNGLVCQGSQAARQNQAYAQGFEWLGENPQRFISKTALELLDILQVRFDSAEHLTDGYVDGRVPVPHLLGLLLDDTLYVVLVGLAVLGFWRKQAVAGKGLVLGWLGYNIIVGSLIFAIARFRQPLIPFVIIYAALAIVQWSQAWASSRQQRYAWASACLLWLIVLPSYLYLPESVGVRSVWQDVRLGFAGVQQANQCQAIRELLQAGDVVAARQLHDRIDAEGRSENTSVSGYTGRRCLALINGQLLEAEAKPEQALAFYQQANPKNNPVQSARILMLEGNLLQRQGQLSAAVARFNFRDVEIINDLAWAWDYLTVVPTTTIDLGSGLDYGYVRGFYQSEHNQPDFRWSSQASALRLPQAATGQAQTLRLHLNGFTNDWQPTRISISLNGQLIDSYQLKPDWHWLEIALPAQPQGSDLLIEFTSSTFVSGPEDLATRVSSRASDPLRLLGFQLDRVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE5</accession>
    <name>A9AXE5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4233"/>
    <dbReference type="EnsemblBacteria" id="ABX06865">
        <property type="protein sequence ID" value="ABX06865"/>
        <property type="gene ID" value="Haur_4233"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4233"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_3_0"/>
    <dbReference type="OMA" id="METERAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4280-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="11"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20805" checksum="9B028B3905A19AE8" modified="2008-01-15" version="1">MKKLTQAEAAILSLLAEQPRYGYELEQIIQARGMRSWTEIAFSSIYYLLKKLEQAQLVAGETSQGDGRPSRMVYNILPSGRVALQESLRTMLSVPQQRYSALLLGMANLPLLELSEVVVALEQYCEELRAQIGRVQQRRAEEQTQSWHIQGLFDYTETMIQAEHDWLTKYLAQIRQQLNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN2</accession>
    <name>A9AXN2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ordered locus">Haur_0798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0798"/>
    <dbReference type="EnsemblBacteria" id="ABX03446">
        <property type="protein sequence ID" value="ABX03446"/>
        <property type="gene ID" value="Haur_0798"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0798"/>
    <dbReference type="eggNOG" id="COG0554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_0"/>
    <dbReference type="OMA" id="FMLMNIG"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="259"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="409"/>
            <end position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="496" mass="53889" checksum="78E96E22E9B47B1E" modified="2008-01-15" version="1">MQYIAALDQGTTSTRCMVFDHNGNVVGVDQREHTQIFPQPGWVEHNPAEIWQRTQGVIAGALAAANIEKSDLAALGITNQRETTVIWDRHTGKAIYNALVWQDTRTDALVRQFAADGGQDRFRAQTGLPLATYFSATKIRWLLDQVEGAQAAAEAGDLLFGTIDCFVAWWLTGGPHGGLHITDTTNASRTLLLNLTTGDWDAELLEIFRIPRSMLPNVRSSSEVYGTCRGQLDGVPLAGILGDQQAATVGQVCFEVGEAKNTYGTGNFMLLNTGERLVQSRHGLITTPAYHFGKQPTWALEGSIAVTGSLVQWLRDNLGIIHSAAEVEPLAASVADNGGVYLVPAFSGLFAPHWRSDARGVLVGLTRYANKAHIARAALEATAYQTREVVSAMAQDSGVELTALKVDGGMVANELLMQFQADILGVPVVRPKVAETTALGAAYAAGLAVGYWANPAELRANWSESKRWEPQMSSDQRDSLYAQWNKAVQRTLNWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN6</accession>
    <name>A9AXN6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0802"/>
    <dbReference type="EnsemblBacteria" id="ABX03450">
        <property type="protein sequence ID" value="ABX03450"/>
        <property type="gene ID" value="Haur_0802"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0802"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_0"/>
    <dbReference type="OMA" id="ATEGREY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-815-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="37"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="34940" checksum="99985FC4FFB0795A" modified="2008-01-15" version="1">MTGLNIQAWAEQLRRQVGQVVVGKQTSVDLLLTALLCEGHVLLEDVPGVGKTTLIRALAQSLDCQFRRVQFTPDLLPSDVTGLNFYNQKLSEFQFRAGPLFANIVLADEINRATPRTQSALLEAMAEATITIDGETHQLTRPFLVLATQNPIELEGTFPLPEAQLDRFLLRVNLGYPSEAEEHAIIQRFNQGDPWMAMQAVSDQSQLLAAIQAVRTVHLSDAVRNYAIAIVRATREHSEIELGASPRGSLALTRAAQAWALVHGRDFVLPDDVKQLVPSVLAHRLILNAEARLAQRSPEKILADIVKSIATPVEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS1</accession>
    <name>A9AXS1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murA</name>
        <name evidence="9" type="ordered locus">Haur_0837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0837"/>
    <dbReference type="EnsemblBacteria" id="ABX03485">
        <property type="protein sequence ID" value="ABX03485"/>
        <property type="gene ID" value="Haur_0837"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0837"/>
    <dbReference type="eggNOG" id="COG0766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027387_0_1_0"/>
    <dbReference type="OMA" id="CDPHRAT"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="428" mass="46135" checksum="DA3AA49DB72E53EC" modified="2008-01-15" version="1">METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSLGIECSWLEENVLRVHAATINTSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIGHRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLDEMSVTGTEQAIMAAVLASGTTTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFIGLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVPKIDDMPWPGFPPDLMSIALVIATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHRAVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISNIAQIDRGYQRIEQRLAALGARIERRPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY12</accession>
    <name>A9AY12_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrate ABC transporter, ATPase subunits C and D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2338"/>
    <dbReference type="EnsemblBacteria" id="ABX04978">
        <property type="protein sequence ID" value="ABX04978"/>
        <property type="gene ID" value="Haur_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2338"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OMA" id="KGFENHW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2366-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="24"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="276" mass="30282" checksum="5EA287818F62E747" modified="2008-01-15" version="1">MAPRLLPRTTPNTAILPMEPAPLLEISSVGKNYPSGQGQINILHDIDLTIQSGEFISFIGHSGCGKSTLLNMIAGLTSISTGTMLFDGKSIAAPSPERAMVFQHYSLLPWLSVYQNVYEAVDSVQTEMSKAERKALTNDVLARVGLSNHMHKKPMQLSGGMRQRVAIARAFAVHPRMLLLDEPFGALDALTRGSLQEELLGLWSGDARTETVVMVTHDIDEAIYLSDRIVVFSDGPGATIKEVITVDLPRPRDKQSLMNSPTWNNLRTHLLLSLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYG1</accession>
    <name>A9AYG1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ordered locus">Haur_0895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0895"/>
    <dbReference type="EnsemblBacteria" id="ABX03543">
        <property type="protein sequence ID" value="ABX03543"/>
        <property type="gene ID" value="Haur_0895"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0895"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_2_0"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="105"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="178"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="263"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="40603" checksum="A82D531B20CBB978" modified="2008-01-15" version="1">MTKRLGILGGGQLARMLVQAAIPLGIETVVLANRNDEPAALVSKAVVGEWSDRALLDQFAQAVDVVVLENEFIGSEKLAYLASKGVQLVPDQATLGLIEDKAQQKLTLAAAGLPVPALALIESLDDVAAFGAEHGFPLMLKTRRNGYDGRGTAKIRSAEEIASACSSLGFPENPVFVEAWVPFEAELATLIIRSVSGEQCVYPVIETYQPSGVCRVVRAPAPFSAAIQQQASEVAQATAAALGGLGILAVEMFLTSKGQILVNELAPRPHNTGHYSIEGCYCSQFENTIRAALGWPLGDPQLRHQSAVMVNVLAPTTRPLESSLIQTALKPQVHVHWYDKRSAKPGRKIGHITAVGAEPSEVEARAQAAVDQLERVLAEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ1</accession>
    <name>A9AYJ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0925"/>
    <dbReference type="EnsemblBacteria" id="ABX03573">
        <property type="protein sequence ID" value="ABX03573"/>
        <property type="gene ID" value="Haur_0925"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0925"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="ICGFDVQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-939-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="256" mass="28567" checksum="FDA7341AE31993A1" modified="2008-01-15" version="1">MAPVLVVEHLQKHYGNHKAVKDVSFSVEAGEIFGIVGPNGAGKTSSVECIIGLRPATAGTIQLLGRDLKQHGSYIRSKIGVQLQQATLPDRLTVAEALQLFGSFYPQARPWQKVIEEWGLAEQAKTAFANLSGGQKQRLFIALSLIHDPEIVFLDELTTGLDPQARRITWNLIQDVRKRGKTVMLVTHFMEEVERLCDRIAVIDQGTVIALDTPDRMIAAYQHDLRQQPVPSRDLPHPERVTFEDVFLRLIGQPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ8</accession>
    <name>A9AYJ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0932"/>
    <dbReference type="EnsemblBacteria" id="ABX03580">
        <property type="protein sequence ID" value="ABX03580"/>
        <property type="gene ID" value="Haur_0932"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0932"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128755_0_0_0"/>
    <dbReference type="OMA" id="KEALWAP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-946-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="PTHR13323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18191" checksum="CA649A52B339564C" modified="2008-01-15" version="1">MDPQLASLIVPPEEVAHIDECLTRLVEDTGGNYALLLDKSGQVIAASGDGNRQDTTALGALIAGSFASSQQIAKLLREKDFRMLLQQGVRENLFIALIDDQWILTIIFNKGTHIGLVKVLTKKATEELASVLERVRKQHKSRDEVLGSNFRTSMEDTIDLLFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ9</accession>
    <name>A9AYJ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0933"/>
    <dbReference type="EnsemblBacteria" id="ABX03581">
        <property type="protein sequence ID" value="ABX03581"/>
        <property type="gene ID" value="Haur_0933"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0933"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118613_4_2_0"/>
    <dbReference type="OMA" id="ASEMIGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-947-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="PTHR13323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="12729" checksum="4B254809D52A2606" modified="2008-01-15" version="1">MSKTLRDVLNQFRTLENVELAAVAGTDGLLIESSARSGVDVDAICAVASNGLAMAEALGREINKGGSVQTVLEYDQGLILLEPVSSDAMLVVLTSSRELLGKLRYMAQAHRANLDAALAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ5</accession>
    <name>A9AYQ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2393"/>
    <dbReference type="EnsemblBacteria" id="ABX05033">
        <property type="protein sequence ID" value="ABX05033"/>
        <property type="gene ID" value="Haur_2393"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2393"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="PRHTVYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2421-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="37928" checksum="2582991FC22CB7C9" modified="2008-01-15" version="1">MTKTVLTAEQWKLAESPDPVVLEVRNLTKRFPVGGLFRSKQVHALTDVSFAIRRGEVLAVVGESGSGKSTAARLIARLMEPTSGEIIFRGQNVLQTEKRGASLSYRSGVQMIFQDPFGSMNPTHSVAHHIMRPLQIHHKVERRSDLLPRVHELLATVGLNPPADIANKYPHELSGGQRQRVAIARALAVDPEIVLADEPISMLDVSIRIGVLNLMAKLKKEIGIGYLYITHDIASARYFADRIMVLYAGQMMEGADSDELIGNPAHPYTKLLLSAVPNPEVALGQREVVARGEPPSLIDPPPGCPFAARCPQVKDVCRKVMPDVQTIAPNHWVRCHLYGEGTGGTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT1</accession>
    <name>A9AYT1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Macrocin-O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2419"/>
    <dbReference type="EnsemblBacteria" id="ABX05059">
        <property type="protein sequence ID" value="ABX05059"/>
        <property type="gene ID" value="Haur_2419"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2419"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062821_1_0_0"/>
    <dbReference type="OMA" id="WRGGACI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2447-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05711">
        <property type="entry name" value="TylF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="31699" checksum="01E835E8DD5C90E3" modified="2008-01-15" version="1">MANEAAQLYLDLLKRCIMGLVYEDQPLRNIVYEPFSINAPYTGPYSTFDREKRLNGHEWPSQAHTMLSMHRLNNIQSLVTDILEKQIPGDLIETGVWRGGATIFMRGILKAYNCNDRTVWVADSFQGFPKNEEEGLLGETESPGLPQEQHGPPPKPIQDILDLLWKGTSYEDVRQHFEQYGLLDDQVKFLKGWFCHTLHQAPIDNLALLRLDGDLYDSTYDALEALYPKVSQGGYVIVDDYATFEECYNAVHDYLESIGAEVTMQPIDEDSVFWQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ17</accession>
    <name>A9AZ17_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4425"/>
    <dbReference type="EnsemblBacteria" id="ABX07057">
        <property type="protein sequence ID" value="ABX07057"/>
        <property type="gene ID" value="Haur_4425"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4425"/>
    <dbReference type="HOGENOM" id="CLU_256826_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4480-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732258" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1363" mass="151269" checksum="E4E41011EBD46130" modified="2008-01-15" version="1">MIPIRRVMSMLIVSSMMIGIVPSTPAQSTAPKAHPTANQAPLNDLLLDSDDGESSTLNVEADPCPEPAASLELPDLEPTPNQPQNASVKHTNQALPHTNYPLNCEFARDREVLAMINPESFSITNANQSFTTDSVTVPETTQMLRFEYMVGRKTADSITPLHIEVLSGANFATVTNISNSRIKSQYRLGWQNGALNIQAFRGQTIKLRFINDWWWTDQPSAQVRNIQLTQEIPDWELSTVGEFAIQNDALIGAHAVITGANANLTSMPINITYQTQSLSFNYRTGRWLNDGHAPLFVDILSGPSFTTVTRIDQGTLGGRLTDGWREAVVDVQAFRGQMIKIKIVNDWWPTEPQVTSLDRFMLNWAVPGWDISNASFVRTHSLPSNADIHPLNTDFEQGFVGFDVIENAAFEQPKQLVSVLEQTPINLQGIKTKATSIDFLVPAATTSVHFEYMLGDLDNPNTTRSLQVAILSGEAFEIRELPKGHEFISSQQAGWQLGKIDLVGYRGKTIKLQFTNASLGKPSSQIRQLQVMQDVPGWHVSNHQLVSFDTHEQYPNHVYVHGNATQLTSFGFTVPLTAQQVRFDYQAGHSHDNAARQSVAISVLSGDHFEVATLLPKNYLSGSTNQGWQRLAIDLQRFQGQTIKVRFQLEAQNKAYLRLDNFQVGQILAGWSVSEHTPISLESAGTSGQAVRFTGNNATITSDAWQVPTDTQTLQFNYKAQLSDPNARSFIKVHVLSTDDFTVITPIDAKLVYGTANNGWLQAQLDLAQFQGQTIKLQFKSHTSNDAIVWLDQLQLIAGPQRSKQVTQQAPDYSFIEMTQNAQQLTSSSVEVASDSQFLRFVYQVGNKDQGNARHYLAMEVLSGANFTTVTRIDQNQLRASLNDGWKIAQLPIQQFQNQTIKIRFVGPDLVSAPIVRIDKVALLSPRATLTNPIATTGTTYLNVPLTEFGGPTTTATMTITSLVVYDEYIDLAGEVYYGNTSYPFALTGDLYHSNLGTPGDVVAELQDTTRTFDALYLAFRQQPFGPQTNPSIINENLSLYLQRQGTREATLIDLGLNDSSNMLLNPIFQASSLSPAEYGSDYWFGKLVEPESTFEALGDPDEKKWTWTRRTIGEDCSLFQQLTFGVVVTKPYDIGVNEGNFGSQLEVLGSVTNGYVTPGQSWPDHSCDIYDEDNAGVSLGSKDDPVTVKFVSSGNGLTGNSAQGDYLSHVIFGGEAAIFKNNTLWFDQFMGHLITSIDLVSKFYSTPISVGDVSQLFPEGTPAMDDKPALSNSMILNDWDDNPNTKMKVLRVPFQQSVLVNRKNYFMVLVSVTCKKQTVNKDMQLKIFWHIPLYDKVTKKELNKGLYNKIFLIDYKSGPCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ19</accession>
    <name>A9AZ19_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="8" type="ordered locus">Haur_4427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4427"/>
    <dbReference type="EnsemblBacteria" id="ABX07059">
        <property type="protein sequence ID" value="ABX07059"/>
        <property type="gene ID" value="Haur_4427"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4427"/>
    <dbReference type="eggNOG" id="COG2344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061534_1_0_0"/>
    <dbReference type="OMA" id="HEQRKAG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="81"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="92"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="24361" checksum="545D93A4E36A51CB" modified="2008-01-15" version="1">MDISPNAIPDVVVRRLPIYARSLSYLAEEGVRSVSSQELGERIGVTAAQIRKDLSYFGEFGKQGIGYNVEYLLGHIRRILGLHEVWPVVLVGVGPLGQAIARYEGFRTRGIDIIGVFDNDTSKIGLQLGRNTVQPDSDLPKILQEHNIRLAIVAVPAVRAQEVVDVLVQNGVQGILNYAPIVVQTPDNVWVRHIDPVALLHSMTYYLSREDEHHAMNEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ71</accession>
    <name>A9AZ71_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Translin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0969"/>
    <dbReference type="EnsemblBacteria" id="ABX03617">
        <property type="protein sequence ID" value="ABX03617"/>
        <property type="gene ID" value="Haur_0969"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0969"/>
    <dbReference type="eggNOG" id="COG2178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099315_0_0_0"/>
    <dbReference type="OMA" id="EKTHGDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-983-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="PTHR10741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741:SF2">
        <property type="entry name" value="PTHR10741:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="SSF74784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24437" checksum="3179B79A188D5AC9" modified="2008-01-15" version="1">MSIETTSLISELEAIHATREIALKSARELIRQCANTIRAVHRHEWALAEPLLQATAAAAQSLRERLQDYPALLYAGYTQDAFKEYAEAALTLALVRGETLPTHHALGVEAAAYLNGLAEAASELRRYILDGLRHGKVDSGERLLDQMDEIYSFLVTVDFPDAVTSGLRRTTDALRAVLERTRGDLTSAVRQEQLVAALARFEQHMGLPPAALQESTPDETDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH9</accession>
    <name>A9AZH9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2485"/>
    <dbReference type="EnsemblBacteria" id="ABX05123">
        <property type="protein sequence ID" value="ABX05123"/>
        <property type="gene ID" value="Haur_2485"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2485"/>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_663543_0_0_0"/>
    <dbReference type="OMA" id="YYTRKVE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2513-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="44396" checksum="E68DE0F6A9F309B3" modified="2008-01-15" version="1">MPNPSNPPTVLATLDIAKHTHWFAVFTADLTPLIPPHSITTDATALQEVIDTLTTLAQTRPIALAMEPTGIYHLPWLHALTAALPSTVTCLLVHTTAVHQARAVLTAGRQRKTDARDCYAIAAAVRDGHGRPWSPPSPQQTHFRTWAAQEAATTAAMAQLAHALQRLTDLLWPGLVARRTAACKPLVSSRPWTRQSIQAILLHYPDPHAWRSLSVAAIQARLKALDVRCGPMRAQQLAAILAAQVVLPPDQTRSLASRLSTLMQQYCLHAAQLAALHAEAETLVTASWAAVLCSIPGMSPVLAARYAAAVGDIHAIRSAKALWSLAGLEPSIYASGTTARIGRSSLAGRVPLRQALIRIGASLGRHCPPVRACLQAARARGKPITVALIHAANKANRILFAMAMSQQPYQALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP3</accession>
    <name>A9AZP3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4465"/>
    <dbReference type="EnsemblBacteria" id="ABX07097">
        <property type="protein sequence ID" value="ABX07097"/>
        <property type="gene ID" value="Haur_4465"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4465"/>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560015_0_0_0"/>
    <dbReference type="OMA" id="LAFCFGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4520-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="479" mass="51458" checksum="D5921694769418C2" modified="2008-01-15" version="1">MFATFDQRRRREFGLIVGGTLVGMGLGAAAAFVPSFLVVAGLVALLVGAWFARSIHSMLTATVLVATLLPFGTLPFKVGLTPALLELALLALYAMLVVRSLADPERTWRWGSLAPWVILLLASSFFSFIIGSNGSPDSLLLHNYFKLLLGICLFLGVQNALDSLEQARWWLRLLILAGWAAALLGIGLRFAPDAMALRFLTALAPLGYPASGRVLRYVEDDPSGFERAIGTSVDPNGFGGMMALLGAIALGQALAQRPVLGRKWLWLITASFALAVFLTSSRAALGGFMIAGLFLATVRYRQLWWLIGAGGLAGAIAIVGLGKGGDFVERIVEGIQFKDQANQMRLAEFRNAIAIIREYPVFGVGFGRAPNIDLTTGVSSVYLALGSRMGLVGLGLYILTALAFLVLTTQAARRCERSVSDAIIGLQAAILAALAVGLLDHYFFNIEFPHMGTLFWGVVGLAMVFMREVKNDQLTSSLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS3</accession>
    <name>RIMO_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="1">S12 MTTase</shortName>
            <shortName evidence="1">S12 methylthiotransferase</shortName>
            <ecNumber evidence="1">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rimO</name>
        <name type="ordered locus">Haur_4495</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZS3"/>
    <dbReference type="SMR" id="A9AZS3"/>
    <dbReference type="STRING" id="316274.Haur_4495"/>
    <dbReference type="PRIDE" id="A9AZS3"/>
    <dbReference type="EnsemblBacteria" id="ABX07127">
        <property type="protein sequence ID" value="ABX07127"/>
        <property type="gene ID" value="Haur_4495"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4495"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_0_1_0"/>
    <dbReference type="OMA" id="HYAYPTG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000374864" description="Ribosomal protein S12 methylthiotransferase RimO">
        <location>
            <begin position="1"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="MTTase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="166"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="1">
        <location>
            <begin position="401"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="469" mass="50947" checksum="567DE943FB7BAF1D" modified="2008-01-15" version="1">MKFHIITLGCPKNTVDSEGMHGILTREGHTAVDSSDGADVVIVNTCSFINAAREETVGVLQELANNKAPGQKLIAAGCMAESHGDVLRSRVPKLDATLSTKEWMRIGSVVAGGVAPSKTTGFGIPLMGGAPSAMPSTGLNLSLTPAATGDSLGAYGDWRTTAITRNKRGPSAYLKISDGCNLRCAFCTIPSFKGDMRSKAVGSILGEARELVEAGVQEIILVAQHLTDYGRDLGMKQNGLGVLLEELAAVVPADRWIRLMYAYPQSVTPDLVETMARLPQLCHYVDMPLQHAHPDTLRRMRRPPDTDKTKAIVNSLRQAMPDLSLRTTFIVGYPGETRDEFKALLEFLEEMQFDRVGMFRYSLEPGTVAGELPDQVAERVKERRWNEAMAVQQVISRARTARFVGQTMKVLVEGTGTDDDGRAIVVGRSYRDAPEVDGLVFGYGAADVGQFAKIAINKTTDYDLWGEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU0</accession>
    <name>A9AZU0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4512"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07144">
        <property type="protein sequence ID" value="ABX07144"/>
        <property type="gene ID" value="Haur_4512"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4512"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_4_0"/>
    <dbReference type="OMA" id="AVGWKEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4567-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="191"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="41746" checksum="6D9DA5F4BAA4D245" modified="2008-01-15" version="1">MIIEALVAMKILIISKALTAATYHRKLELIAAEPDVELTAIVPPMWFEPGVGEYPLEVQTPRNYRMHVVPLGHNGHHHTFWWQGLGKLIAAEQPGILHADEEAFNLATFQAFWHARKTNAKLCFYNWADVARRYPPPFSFFERYSYRHAAHAIAGNHLAKQLIRDHGYPGPISVIPQFGVDEAIFRPAPEPLPAKPFVVGFFGRLMRSKGVLDLLAALERLPSDIHCRLIGKGDLSSEVEQRIAKAPLAGRVTLEPLIPSSAMPDAMRSVHAYVLPSRTTPNWKEQFGRVLIEAMACGVPVIGSNSGEIPHVIDTAGLVFPEGDVAALAEAIHKLYLDEKYRQNIAEAGRQRALSHYTQASIAQQHLAVYRSMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B080</accession>
    <name>A9B080_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2551"/>
    <dbReference type="EnsemblBacteria" id="ABX05189">
        <property type="protein sequence ID" value="ABX05189"/>
        <property type="gene ID" value="Haur_2551"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2551"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_8_3_0"/>
    <dbReference type="OMA" id="IQFAMIS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2579-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="508" mass="56167" checksum="6F03E90B58351386" modified="2008-01-15" version="1">MLKDLVRIFAFCAKELNAIRRQPLLLVGLIIGPFLILSLFGVGYQGEQPKLRTGIVVPPGHRDDPQVTELIKRISNTFVIDAERHIYESEEPAVAALNNDELDLVEIFPLEMTTVYSTGKAVDIRFIYSEVDPLLRSWIEYLSYTQINELNKGMLFSVVGQSQQQIGTLRDYVSDARQQISQLREQLNSNKRDEARQTIKTLRESGALQLIALSMTQNGASETSSSTQSLSSFQASLDGLDRDLAAGGTLEQQDQKLAELDTRLGELDQQADRVQTIDPAVVVSPLRSVASNLAPIESLGDITKDPATAYVRFYTPAVLALLLQHMMVTLAGLSLVRELQQGTLEMFRVSPLSAFQTLVGKYASYTILSAVIVSVLVSLMVFGLGVPFYTGQLLNFALLTFMLTIASLGIGFLISSVVSTDSQAVQFSMLVLLMSVFFSGFFISLKSFLPFVQNIARGLPVTHGIANYQQIMLLNRAPEASTYIWLGGIALVSFLLSWLIFGRQFQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B084</accession>
    <name>A9B084_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2555"/>
    <dbReference type="EnsemblBacteria" id="ABX05193">
        <property type="protein sequence ID" value="ABX05193"/>
        <property type="gene ID" value="Haur_2555"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2555"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_2_0"/>
    <dbReference type="OMA" id="GPIFYRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2583-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="22653" checksum="157473B871FC7EB9" modified="2008-01-15" version="1">MKSEPSEGSDEPNVYQSLLHRQRPGGRSAKVHAAVLQATGELLFEQGYAQLRIADVAQRAGVHETSIYRRWKTKAMLVADTVLALFDQHVPNPDTGSFREDVLSFLPSLVRYLQSPEGEALGRACVDVSNLAEAAEARQAVWGIWVDQFGVLVERAIARGELPATINAQIFLEMLIGPFFLRLLVTGEPLHEAMAVQVIDLLLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B7</accession>
    <name>A9B0B7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2588"/>
    <dbReference type="EnsemblBacteria" id="ABX05226">
        <property type="protein sequence ID" value="ABX05226"/>
        <property type="gene ID" value="Haur_2588"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2588"/>
    <dbReference type="HOGENOM" id="CLU_1882894_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2616-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15473" checksum="2F1AB762FAC01946" modified="2008-01-15" version="1">MDSHCAACQGFISYAENCLQRHFQDQQFVRQQCDAQHGGRECLVLYRSPICSALLVLSDGEYHLALGKHTAPFITNQQLKLDGSQGWYNVLDLLDRQANPLQRLWQTFKRHKPNDLAWVAKQLDGKLAQLTTLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C2</accession>
    <name>A9B0C2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2593"/>
    <dbReference type="EnsemblBacteria" id="ABX05231">
        <property type="protein sequence ID" value="ABX05231"/>
        <property type="gene ID" value="Haur_2593"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2593"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_1_0"/>
    <dbReference type="OMA" id="TPIFMEA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2621-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="46537" checksum="47798E2223FD8174" modified="2008-01-15" version="1">MSVEFKMPKLGESVTEGTVGRWLKQPGESLELYEPMLEVTTDKVDTEIPSPVNGRLLEIRVNEGDTVPVGTIIAVLEDSSSATVAAVGAPAAPAVASQASSNNGGGNSFMSPVVARLVSQHNLDIKQIAGTGKDGRVTKQDVERFMAQGDAAKPAPMPMPTPTAPTPAPMPVIKPSSTPAPMPTITGSLLAKPVAYTPPATPAAPSIEPFVGDELQPLSGMRRAIAEHMVRSKATSPHVTTVMEVDLSTIIAHRDQHKADFERQGVKLTFTPYFVQATVAGLRAVPIVNATYTDEGILLHKSVNVGMAVAIPDGLIVPVLHNADEKSLLGLSRTVNDLAERARTRRLTADEVKDGTFTITNHGVSGSLFAMPIINQPQSGILGIGAIQKRPVVVTINGADAIAIRPMCYLSFTFDHRLIDGATADKFLATVKQQLEQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0D6</accession>
    <name>A9B0D6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoesterase</fullName>
            <ecNumber evidence="2">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2607"/>
    <dbReference type="EnsemblBacteria" id="ABX05245">
        <property type="protein sequence ID" value="ABX05245"/>
        <property type="gene ID" value="Haur_2607"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2607"/>
    <dbReference type="eggNOG" id="COG0622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_3_1_0"/>
    <dbReference type="OMA" id="ICGHSHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2635-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="18535" checksum="3FA7DA3F8683E450" modified="2008-01-15" version="1">MQRICIVSDTHGKFDPRIEQLFIGAAGIVHAGDIGRAQPPIIERLGAIAPVTAVTGNVDWNTALDIYPINTTLEVQGIRIMIQHIGDIPKRWYRQLPQPLPHVVICGHSHIALIEEYQGVLFINPGSASQPRGQLGEPTVAFLDIQENGEFHAEIIPLKMAEFIKHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N8</accession>
    <name>A9B0N8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4625"/>
    <dbReference type="EnsemblBacteria" id="ABX07256">
        <property type="protein sequence ID" value="ABX07256"/>
        <property type="gene ID" value="Haur_4625"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4625"/>
    <dbReference type="HOGENOM" id="CLU_1014793_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4682-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="32287" checksum="2E5DB01869CD3ED7" modified="2008-01-15" version="1">MSNDYFPIEQLIAQQLPEAMALQLHVLPAHQELIAPLPTGYVGPVMAAAEQWLKVHGYRTLGPWMIAWGPTGQPQLRRPVSGALKAIREKDFQTVEVPEQLLLAVPFVGWPVLPHNFTQPVNNVGLNIMGSPLLLALTDSPPTMAWVPVVPRGTNTLFSIERSKIGLLPAPPKPGKQISMLDAWRRAGYTLGRFATIIIGGLGFIISLTVIMGVLIGGEPIASIQGVAYVYTIITGFLAVLWSQAIIITLIIIFAIIGAYKMNAIANWNRFWQQRPVPPELLLGSRGDGQVGTWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0P9</accession>
    <name>A9B0P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1121"/>
    <dbReference type="EnsemblBacteria" id="ABX03769">
        <property type="protein sequence ID" value="ABX03769"/>
        <property type="gene ID" value="Haur_1121"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1121"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_949207_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1142-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="51"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="33481" checksum="327D6AE44BC76CD6" modified="2008-01-15" version="1">MNMTEQPYVPLAPRDASLMDTMLRNEADPAYSRRARRLMQYLDLQDGDTVLDCGCGYGFYTQMIDKLRDLHVVGFDEAFDRLLVGQEHANRATFVRGDGQGMPFANNSFDKILLSEVLEHIPDQQAALHELRRILKPGGILAISVPHANYPLWWDPASWIWTRLGGKPFTHTKFGSIWENHVRLYEPAELVRQVRMADFEVECCEEATHYAIPMTPYVVYGIGKPLIESGILPESWMKSADRMRGDQNQGSKLNPLNLARGIINYVDQLNERPETLDKRSFVNVFVKARKPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B165</accession>
    <name>A9B165_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ca(2+)/H(+) antiporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2705"/>
    <dbReference type="EnsemblBacteria" id="ABX05343">
        <property type="protein sequence ID" value="ABX05343"/>
        <property type="gene ID" value="Haur_2705"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2705"/>
    <dbReference type="eggNOG" id="COG0387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008721_2_1_0"/>
    <dbReference type="OMA" id="AAVMITC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2736-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="PTHR31503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="28"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="225"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="370" mass="39841" checksum="5BFF5D4F3D9884EF" modified="2008-01-15" version="1">MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIGGLLNATLGNAAELIITIVALKAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKFDRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDVFKTQVDDPQLRAISIGVAAVLIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSEFLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQIALFVAPLLVFISMLFDQQMTLFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYIIVGIGFFFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B195</accession>
    <name>A9B195_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of SigK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sigma-K anti-sigma factor RskA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4651"/>
    <dbReference type="EnsemblBacteria" id="ABX07282">
        <property type="protein sequence ID" value="ABX07282"/>
        <property type="gene ID" value="Haur_4651"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4651"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075802_3_1_0"/>
    <dbReference type="OMA" id="ASARMFM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4708-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="28310" checksum="FF98F3184FE29E3D" modified="2008-01-15" version="1">MMDAQLEELLIGYALGILSLDEQQSVEIQIANNPLLRTKIQQLQRTVHQLALAAPRVQPAPIVKQQLLARARASKQTSPITRPTTRRLSLAWAAALALLIALGGWNIGLRNENNQLRTNVAGLEREVASERLRRVQADEQIAKAEQAVAFVVAQTTTSRQLAATEQSPKAVGTMYMQPGNQTAVLVVDGLAPLPEGQVYQFWLARAGQEPIPSDQFSVNAAGHAQLVITADSQVNDFQQVMVTIEAAGGSQTAPGTTVLAGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K7</accession>
    <name>A9B1K7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1244"/>
    <dbReference type="EnsemblBacteria" id="ABX03892">
        <property type="protein sequence ID" value="ABX03892"/>
        <property type="gene ID" value="Haur_1244"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1244"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_0"/>
    <dbReference type="OMA" id="IYQGGAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1266-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="33402" checksum="D096FB4FD0F7472D" modified="2008-01-15" version="1">MMLKRSTNSGYWWFLLPGLILFVMVIAIPFLMNIGTSFTNWQGVGTPKWAGFDNYARLFRDSTFWASFRNNLAMLIAMTIVPTLLGLLLAAVLYDYIGNKFGSGTASFFRAAFYLPQILPVAIAGVVWAWILHPNYGALNGFLETLGLENLTRNWLGNRQTALPSVMMIMVWFQLGYPLVIFMAGLQRIDPEIYEAAVLDGASWFDRFRFITIHLIRPEIFVVLLTTTIASLKVFGQIYVLTRGGPGNATLVPSYFAYQNFFEKANVGYGAAIATVMTLIIIVLTIIFIRRQSAEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L3</accession>
    <name>A9B1L3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    <sequence length="425" mass="45466" checksum="6BC3A28FEEC5807C" modified="2008-01-15" version="1">MQNPSSTAWLGRFLSIWLGQVFSLVGSQLVQFAIIWNLTLRTGSATTLAFATLMAMLPAVLLSPFIGTWVDRMNRQVIMLVADACSMLVTIGLALLFWRGADAVWHIYAALLLRSICERFHATAMGASTVLLVPKTHLARVQGLNQALNGGMNIVAAPLGAWLIAKFPLQVVLSIDVVTALLAILPLLFVRIPQPQRDADRKVTFWQDMREGFNYVIGWRGLLISLIMVSMINLVMTPIGSLLPLLVTKIFGGGASELGWMEAALSIGIILGGVLLSVWGGFKRRIVTALFGLVLLGSFTLLMGIMPSSLIWAAIAMNGLVGLSLPIVNGSFGAMIQGVIAPELQGRVFSLVASFATAMAPLGLLLAGPIADSFGLRVWYILGGVVTIAMGVLGFGLRSVMTMESQSHEAEPPIVEASLSQAEAL</sequence>
</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Brettin T."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
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                <person name="Tice H."/>
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                <person name="Richardson P."/>
                <person name="Bruce D."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
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    </evidence>
    <sequence length="236" mass="26033" checksum="6B97E9F2FFD9ED29" modified="2008-01-15" version="1">MPNSQFASIKRPSAYDTIDSVMNRTDVALQLSWHELAKTYSTRPVYDQLAGELHSGEVLAVRGPNGAGKSTFLRLLCGLERPSAGTIRYQWQGQTYSPNTMRPWIGFVGPDVALYRELSAIEHLQFLAKARGLAADQVYWRELLAQVGLAGREAERVAHFSSGMALRLKYAIALLAKPPVLLLDEPTAMFDEPGRQFVAQLVEQQRQHGLTILATNDQRDAAWADLVLTVGAAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
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                <person name="Bryant D.A."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Maresca J.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="gene ID" value="Haur_2806"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2806"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007487_1_1_0"/>
    <dbReference type="OMA" id="LAWVNKY"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0046872">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="3">
        <location>
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    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="876" mass="95557" checksum="CCC2CB5493109950" modified="2008-01-15" version="1">MTLATNLHRLPNGLTVLTREVHTAPIATNWIWYKVGGRNERVGISGISHWCEHMLFKGTPSMPKGAFDATIARNGGTFNGFTWIDYTAYYETLPADRLSLGLQIEADRMVNSSFDPDEVASERTVIISEREGNENSPSFWLDEELRSTAFKVHPYRNGVIGWKSDLRAMTREDLYTHYKTFYAPNNAVLVVVGAFNTDEVLKQIEALYGPIPQGLPLPEVRGEEPEQQGERRVHVSRPGPNSMIQIAFHAPPATSPDWAALTVLDAVLTGGKSPSFTGGGAQTNRSARLYRALVEGELATGAYSSFMATLDPFLFEIGATVRPDRTVEQVEQALYTEIEKLQQTPISEAELQKIQRQVRAQQAYSLERISNQAMMLGMWQTLDSYERADSSLEEIAAVTAADVQRVAQHYLAPQKRNIGVFTPSNSSGGGQITPTARTFHPALSFYDAKAAEAEATAAANNAPQATRHVLSNGIVVLLQRNPNSPTVSIQGEIALGQIHESSALNGVAVFTAAALTRGTTSRSFHDITNLTEDRGCSISASAGRHSTSFGGKALSDDAPLILELLADVLRNPTFPEREIERLRTQFTTMLRQSEQDTRSQASKAAREQLYPSDHPYYFSPNGSLDTVPGITTADLAAFAKRYHPAATTIAIVGDIDETAILAEVERWFGDWQGQGEPPTTAVPSVDLPPSVLRREIEVAGKTQSDLVWAVPGLARTDPDFYAAMMANLVLGQLGLMGRLGENVRDKQGLAYYATSRIDADVGAGAWIIYAGINAKNVDRALSAIQEEVDRLLAEGISELERSDSVAYLTGMLGISLEANSGIANMLLNIERYNLGLDYVQRYPEIIGSVTLEQIHAAAKRLLSSERYVIGVAGPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B205</accession>
    <name>A9B205_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2809"/>
    <dbReference type="EnsemblBacteria" id="ABX05447">
        <property type="protein sequence ID" value="ABX05447"/>
        <property type="gene ID" value="Haur_2809"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2809"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2840-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="30916" checksum="8634643C2F7220EB" modified="2008-01-15" version="1">MSNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILIDLPGHGRSQPSKALIGIERTPEYLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVASVTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRRYVAKISVFYSAGQELFYQRMQFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVLPNAGHCANMDNPTLFNQLVLDFLHSAPKPHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B228</accession>
    <name>A9B228_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4747"/>
    <dbReference type="EnsemblBacteria" id="ABX07378">
        <property type="protein sequence ID" value="ABX07378"/>
        <property type="gene ID" value="Haur_4747"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4747"/>
    <dbReference type="HOGENOM" id="CLU_1203505_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4805-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="25698" checksum="6381553DFDABF980" modified="2008-01-15" version="1">MSNSPTLCATCKQKPPLWDMMYCAECYQRQLFRQRLGLWGLWMVISVLEMLLNIGVGVVAVSSELAQESSLISLIFSGVMVINSILALCVGVAQTALMKKKIKRWLLWGIAGGLEVLFFWILSMLAYQQFGQVAHLLIFTMACSGICLAIIQSSLMIGQVAQPWRWILVSIGSWSVASLAALLLENQFGDPLLQTIWGHALGRFVYGVFSGLGFAWLLTDRRMYQPKQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C9</accession>
    <name>A9B2C9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1329"/>
    <dbReference type="EnsemblBacteria" id="ABX03974">
        <property type="protein sequence ID" value="ABX03974"/>
        <property type="gene ID" value="Haur_1329"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1329"/>
    <dbReference type="eggNOG" id="COG3728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174116_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1350-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="27222" checksum="0772B15B43F0DCBB" modified="2008-01-15" version="1">MAKQETVQLIIGHRYANESDKAVVACNDYLRMGINRSLKRLSVHDGDLSGKKPNLRSLERWSTEFNWQDRAKAYDAQLEQAKNDALAARRREVFEEGLALDFERVIKLKELAKDLEEQIKEIDDDHPHKRPNVWVRDVKQIGAGEYAEQVEIYRYNSALISDYRGVLDDLAKETGGRKQKQEHVHKGDRSAPIVIDSPALEQAAKELQQWREEQCQMLLNWRNAMPTLPTSPTTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H3</accession>
    <name>A9B2H3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1373"/>
    <dbReference type="EnsemblBacteria" id="ABX04018">
        <property type="protein sequence ID" value="ABX04018"/>
        <property type="gene ID" value="Haur_1373"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1373"/>
    <dbReference type="HOGENOM" id="CLU_1956589_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1394-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14081" checksum="754D8DBE9EB6F8B7" modified="2008-01-15" version="1">MVDLIAAIITAMSTPAVTALVSNRVWVGPDLPQGYTPDTGPAILCVIRGGGFDYTRTILSPSLYVQLYGTDEGVCIDLWRTCCDAWMDRGNGVTRLRPDSSAMPRLLRTQTTLWLFALSGWTAHIKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L6</accession>
    <name>A9B2L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2829"/>
    <dbReference type="CAZy" id="GT20">
        <property type="family name" value="Glycosyltransferase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05467">
        <property type="protein sequence ID" value="ABX05467"/>
        <property type="gene ID" value="Haur_2829"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2829"/>
    <dbReference type="eggNOG" id="COG0380">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_7_1_0"/>
    <dbReference type="OMA" id="YYGFSNR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2860-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="PTHR10788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="486" mass="55451" checksum="64A86BAA8D5AD2D6" modified="2008-01-15" version="1">MQELPNRLMIVSNRLPISIAEQADGTPTIKPASGGLVTALDPILRQARGTWIGWSGTNEADQTVDQLLEHAANSIGYSMHAIHLSQEEQEKFYLGFSNEIIWPLFHDLQSRCNFDPSYWTTYEQVNRKYAETIAQHYRDDTYIWVQDYQLINVACELRQLGIDAHIGFFLHIPFPHIDIFLKLPWREQILNGLLEYDLLGFQTNRDLNNFLICVEALLPDVEIDRSGEYPLILHADRNPTKVGFFPISIDPQEFRAAAHTPNVDNLYSQIREAFSERKIILGVDRLDYTKGIPDRLQAFSALLETYPELQQKISLTQVVVPSREDISEYADLKQTIQQLVSEINGKYTKIGWVPIHYIFRSLPREELLAYYRAAHAALITPLKDGMNLVAKEYAVCGPDDGVLILSEFAGAAMQLSEHSLTVNPYDINGTAQALYNAVTMPRLERIEHISKLRHSINQYDIYWWVDTFLQAANVKRSGAIEQGSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S9</accession>
    <name>A9B2S9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2892"/>
    <dbReference type="EnsemblBacteria" id="ABX05530">
        <property type="protein sequence ID" value="ABX05530"/>
        <property type="gene ID" value="Haur_2892"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2892"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070761_0_0_0"/>
    <dbReference type="OMA" id="VARNCIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2923-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39295" checksum="600F4140845B96AC" modified="2008-01-15" version="1">MNDAMLTVATALAQIRAGVEDFGGRPINGTLVLDNNIEFLPRGLVATAIEAKNCTKLRYLPKDLHAGRLDLSGCTGLTSIPEGLHCFELDLRGTSIEHLPLVHVQNRLNLSNNIHLKSLPRNLKVGSLVLRGCSALESLPEGIDVNFLDLTDCVNFRRWPSTGRISVGRIVARNCINMPNLPNWLGELAQLSVRGCSSLTELPAGLVVHSWLDLGNTEISCLPADSQVSQLRWNGVPIDERIAFQPETISVSEIIDEVNVERRRVLLERKGYEEFFAQAEAKELDRDRDTGGVRRLLQMPMPNDEDLVCLAVQCPSTDRRYVLRVPPTMQSCHQAAAWIAGFDNPDDYKLLKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B362</accession>
    <name>A9B362_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF2179 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4895"/>
    <dbReference type="EnsemblBacteria" id="ABX07525">
        <property type="protein sequence ID" value="ABX07525"/>
        <property type="gene ID" value="Haur_4895"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4895"/>
    <dbReference type="eggNOG" id="COG1284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063199_1_1_0"/>
    <dbReference type="OMA" id="AQIIHKY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4956-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006483">
        <property type="entry name" value="Membrane_protein_YitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="248"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="33792" checksum="528C1175D80424E8" modified="2008-01-15" version="1">MHHLAEVVFLVGYQHLEVFMHRLAIRREQIPGILRDYLVMTIGTLCIALALNIFLDPNNVIFGGVTGIAAMLKTLLGLPIGVTSLVLNIPLFIIGLKRLGGFVFGLRTIFATVMLSVFIDLTANRVGQFVQREPLLYIAYGALLSGIGTGLVLRVGGTTGGVDIVARLLQQWRGIRPGQSMLISSVVVFGAAGWIYGATPVLYALLLAFIETRVIDIVLEGFSDGRSALIVSDKPEAIRDAVLHDLDRGVTMLEGRGGYSGRERAVLMCVISQAEITILKKMIYNIDPRAFVVMTEAVEVLGEGFRPAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B378</accession>
    <name>A9B378_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4911</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4911"/>
    <dbReference type="EnsemblBacteria" id="ABX07541">
        <property type="protein sequence ID" value="ABX07541"/>
        <property type="gene ID" value="Haur_4911"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4911"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_0"/>
    <dbReference type="OMA" id="MNNNFAF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4972-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="5"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="398" mass="41466" checksum="C4CD6C46E0E05009" modified="2008-01-15" version="1">MKQRVVITGIGICSALGNDIEAYWAALLAGQSGVKPLPDLAPYKDPVVGGATPDLPLLTSHRRQPDRMISLAHHAVEQAITMANGLPQDTAVLWGTGYTTISTIEACYENWFTNGKVRADTVPACMPAAVLPHLCTVFDLHGPSTLISATCASGLQAIGIAADLIRAGVIETAVAGASDAPLTKGMYAAWKPLRVLASDLSDPSRACRPFSADRNGLVLAEGAGAFVLESLEHAKARNAPILAEIMASAATTASGSIVAPDLEHQTLTLTKALARAQISIHDVDYINAHATGTKLGDAAEAATIKAVFGEHAKHVPISAIKGATGHAMGASSALEAVATILALRDQVLPPTINWQAGDPDCDLDFVVEGARQQTINLAVKESFGFGGSNAVLVLRRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F6</accession>
    <name>A9B3F6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1475"/>
    <dbReference type="EnsemblBacteria" id="ABX04119">
        <property type="protein sequence ID" value="ABX04119"/>
        <property type="gene ID" value="Haur_1475"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1475"/>
    <dbReference type="HOGENOM" id="CLU_2633248_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1497-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8967" checksum="1679A8D27FB1EEA3" modified="2008-01-15" version="1">MIGTEPLYIEQLKVEAERLQRRFEQATDVDEFIRVSQEASRRIAVLAPIASIIQRYMLISELAHREYEAHKPQPSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3J7</accession>
    <name>A9B3J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2931"/>
    <dbReference type="EnsemblBacteria" id="ABX05569">
        <property type="protein sequence ID" value="ABX05569"/>
        <property type="gene ID" value="Haur_2931"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2931"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820783_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2963-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="128"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="225"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="338" mass="36654" checksum="C72652AA722C1EF7" modified="2008-01-15" version="1">MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANNQELVVANAALTSINWHIVVVAPKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITLLATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDELGFLARAFNQMASKVQSAQQSLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPITGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAMLVGVSADFAQDLIQSGINLDSVTTMANLQAAVRATLNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K0</accession>
    <name>A9B3K0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_2934</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM175 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05572">
        <property type="protein sequence ID" value="ABX05572"/>
        <property type="gene ID" value="Haur_2934"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2934"/>
    <dbReference type="eggNOG" id="COG3548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090238_1_0_0"/>
    <dbReference type="OMA" id="TGWMGEN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2966-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010617">
        <property type="entry name" value="TMEM175"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06736">
        <property type="entry name" value="TMEM175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX05572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="194" mass="21660" checksum="43B0D0DBA8DF384E" modified="2008-01-15" version="1">MKTQRLEAFSDGVLAIILTIMVLELKIPHGDTWADIQPLVPVLLSYILSFVYIGIYWNNHHHMLHVTNQSNGAILWANLHLLFWLSLVPFTTGWMGENHFATIPTAAYGIVMLGAGVAYWVLQGTIIRSQGPNSSLAKLIGRDLKGKLSPLLYTVAIGCAFIHPALAGFFYVAVAIMWLLPDRRIELHLNELED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L5</accession>
    <name>A9B3L5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2949"/>
    <dbReference type="EnsemblBacteria" id="ABX05587">
        <property type="protein sequence ID" value="ABX05587"/>
        <property type="gene ID" value="Haur_2949"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2949"/>
    <dbReference type="eggNOG" id="COG5628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1693095_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2981-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17688" checksum="EBF30618C5B42DA1" modified="2008-01-15" version="1">MQLIQLRPILVEQQAQLAALIADYLAELDPTASGEYPYLKSYWEDAERVPLWIERAEQRIGFVLLNRYALLPQTTLAIAEFYVEPHARGQGLAQQTAWLLFDRFPATWEIRCLASNRAGLSFWQSTLDRYLGHACPALDGAAYGWDGTIWSFVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N8</accession>
    <name>A9B3N8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05610">
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        <property type="gene ID" value="Haur_2972"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2972"/>
    <dbReference type="HOGENOM" id="CLU_1600446_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3004-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18751" checksum="57FC1E6B5442E5E0" modified="2008-01-15" version="1">MEFELTNAQREAMLQAWQTLSDQALPEERLSFAGLQALPRLVEQALNNGDQTSLTASLINPIYWHQTASYGHGLLARERRVPIDHAAYRLSWWLWLRLYNLANAQLWFDQGLRYATLGQFTAEHQEPAACPLQNGIQVELAAVLEQRLLVPSGFHCCHGLVASNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R1</accession>
    <name>A9B3R1_HERA2</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="3 4">
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2995"/>
    <dbReference type="EnsemblBacteria" id="ABX05633">
        <property type="protein sequence ID" value="ABX05633"/>
        <property type="gene ID" value="Haur_2995"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2995"/>
    <dbReference type="eggNOG" id="COG4309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097418_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3027-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015077">
        <property type="entry name" value="DUF1858"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018720">
        <property type="entry name" value="DUF2249"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038062">
        <property type="entry name" value="ScdA-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08984">
        <property type="entry name" value="DUF1858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10006">
        <property type="entry name" value="DUF2249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140683">
        <property type="entry name" value="SSF140683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1858" evidence="1">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2249" evidence="2">
        <location>
            <begin position="95"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2249" evidence="2">
        <location>
            <begin position="181"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="28935" checksum="32F2157B849F11FD" modified="2008-01-15" version="1">MITATMRVGELLGRHPELEDWLVLNVPRLARLSNPHLRRILSRWLTLSQLAQMMHLEVDQLLMAVNQALNATNQPEVTPQEPPGWLQERPIYRTIQVDQLTNEVDDPVQLILRSAKAVPAGMVLLLVNSFDPKPISAALDHQGFVSWQRPNRERWDCYLYRQLPGEEQWFASRLVLQQPTVIDNRGLKTPLPLVNTLAALTTLEPGQQLLALTDIQPTYLYPMLEERGFIYSTSRAIDYGYITTINRPLISVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T1</accession>
    <name>A9B3T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3431</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3431"/>
    <dbReference type="CAZy" id="GT9">
        <property type="family name" value="Glycosyltransferase Family 9"/>
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    <dbReference type="EnsemblBacteria" id="ABX06067">
        <property type="protein sequence ID" value="ABX06067"/>
        <property type="gene ID" value="Haur_3431"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3431"/>
    <dbReference type="eggNOG" id="COG0859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038371_0_0_0"/>
    <dbReference type="OMA" id="HMAVTQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3468-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
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    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
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    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735242" evidence="2">
        <location>
            <begin position="27"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="40606" checksum="2735C239AA1A8595" modified="2008-01-15" version="1">MKALLRSTMVRGLALALAGFTRPAPAQPQRILVIKPDHLGDVLLLTPALRALRYSQPHAQISVLVGSWATRLLADNPDLDAIETCEFPGFVRGAQPSTLAPYRLLWREAARLRSMNFDTALIARDDHWWGGLLALGAGCGRRIGFAHPLVAPTLTKALAWNSNEHVTKQALDLVAALGSDQPQTQTLRFMPSAAEHAWAEAWLAQHQIQKPLVAIQAGSGGAAKLWPAERWAQVAEQLANQAQIVLTGGPADAVDVAAISQQLQIPHLNAVGQANLGQLAALFGRCALVLGVDNGPLHLAVSQSTPTIHLFGPGDKRRFGPWGDPTRHVVIDAELACSPCGVLTHCPRQTKPSECMTAISVQHVIGHAKRLLDQAGTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3W8</accession>
    <name>A9B3W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3468</name>
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    <organism evidence="4 5">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3468"/>
    <dbReference type="EnsemblBacteria" id="ABX06104">
        <property type="protein sequence ID" value="ABX06104"/>
        <property type="gene ID" value="Haur_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3468"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_7_0"/>
    <dbReference type="OMA" id="IVPHFYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3505-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="153"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="46532" checksum="290BEA20946D012D" modified="2008-01-15" version="1">MPERILVADDNEALSQLLELILVEHGYEVTLANDGGDLLAKAQLQIPDLMIVDILMPRIDGYEAIRQLRNDTRLAHIPIIVLTARTAIEDVVTGFELGADDYIVKPFQMPELLARVRAQLLRATRRPVLNPLTGLPGNILIEEEVNHRLRQQQAFALLYLDLDNFKAYNDSYGFARGDLVIKLLATILTEIKAEYNDEGLFIGHIGGDDFALIMASEHVNALCEDLIRRFDQRILTLYDPNSSNKPVPIQTLSVGVVLHREDMQQTYHDLSRTAAEMKRVAKQQTGSVYVVDRRAQKQTIEQDRRKRGPTIGVIAQDVGLVDMLSDLLQQQSLFVIEADSEIMPDALVLGYRDVLPHVPERWQSLPQITLKLNQSSYEQGFAQLQIQTGLKPTIPIHEYLSLALHLVRLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y4</accession>
    <name>A9B3Y4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine rich repeat variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3484"/>
    <dbReference type="EnsemblBacteria" id="ABX06120">
        <property type="protein sequence ID" value="ABX06120"/>
        <property type="gene ID" value="Haur_3484"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3484"/>
    <dbReference type="eggNOG" id="COG5330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_606597_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3521-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="451" mass="49730" checksum="CC7793A1E1800FEE" modified="2008-01-15" version="1">MNMLDLNQVDQAAMLSLARNPQTDPQQLIALTEWLKLQQGADSAQPSTSFAYLKSQAPQGPLAVILERRTSPLLEALIANPNLPPMLALEFAADVPAAFFANPALPIWLQHDPALFKRMEPLRCMQFLSYPAIPQVILASIQSISPEIAQTVHLHSASNPQLDADWYADYQHYREQVALPDATATTLLQELIGLNAINQPMLSWLRQSPAEQHQALFNRAPATPQPVIEPQTLNFTPNYPRLLESPLAERIQVAHSNDIKGLAILAEDDDLSIRLLVAQNPATPRTVHQLLELDDSQHVRAALARNPNISPKLLLTLARDYTWSAVPIRVAAALNPVATSEILELLAQDQASLVRQTVGQNPQASAEILDHARQRALIEALYALDPWLHMLALGNPATPIEHLAKGARSPWWLGRAALAENPSCPSNVLEQLTNDGNCYVQRLAQTQLNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B453</accession>
    <name>A9B453_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4956"/>
    <dbReference type="EnsemblBacteria" id="ABX07586">
        <property type="protein sequence ID" value="ABX07586"/>
        <property type="gene ID" value="Haur_4956"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4956"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_22_0_0"/>
    <dbReference type="OMA" id="LYIERWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5019-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="18631" checksum="4FF6CE4DF41FDD66" modified="2008-01-15" version="1">MIGLAAPLSLRAATPNDESLLINLYASTRAAELARVDWDETRKTDFINMQYHAQHTHYMQHYPDGSYQIVLHKAKPVGNWYTFQSSTLMRVLDITILPQFRGRGIGRQLMTQFIAEAKASQRRIRLYVYKENPRVSTWYERLGFQAVGGLSMYTEMEWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B484</accession>
    <name>A9B484_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoK</name>
        <name evidence="6" type="ordered locus">Haur_4987</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4987"/>
    <dbReference type="EnsemblBacteria" id="ABX07617">
        <property type="protein sequence ID" value="ABX07617"/>
        <property type="gene ID" value="Haur_4987"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4987"/>
    <dbReference type="eggNOG" id="COG0713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144724_1_1_0"/>
    <dbReference type="OMA" id="FDVWLSR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="5 6" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="105" mass="11154" checksum="E86B1E48572F8C64" modified="2008-01-15" version="1">MVGSVPLVWVLTLAAGLFCIGLFGALSRRNIVGMLMGIELMLNSVNINLVAFWRYLQPTGTAGLVFAIFTIAVAAAEVAVGLAMVIAIYRARLTINADEIDTLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B6</accession>
    <name>A9B4B6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0021"/>
    <dbReference type="EnsemblBacteria" id="ABX02673">
        <property type="protein sequence ID" value="ABX02673"/>
        <property type="gene ID" value="Haur_0021"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0021"/>
    <dbReference type="eggNOG" id="COG3424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034992_0_1_0"/>
    <dbReference type="OMA" id="PIWGLGC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-21-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="PTHR11877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chal_sti_synt_N" evidence="3">
        <location>
            <begin position="4"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Chal_sti_synt_C" evidence="4">
        <location>
            <begin position="216"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000451-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="38896" checksum="55E39E80286945F9" modified="2008-01-15" version="1">MPRIQAIGLGVPQYCVPQRAVQELVAQRFAPAFPEIQRYLTIFRHAQIDTRYLVRPLEWWHEPRSFAECNAIFIEEALNLSCQAIEACLQPLDLTPNDIDHLVVVTTTGLAAPSLDARLMQRLGMQPQTRRTPIWGLGCAGGLGGLNTAFDYLRAEPNQRVLLINVEFCSLTYLADDFSKRNLIATSLFGDGVTAVLLEGDQVAPRGSGLGQIVGTLSHLYPDSAEIMGWNVVNSGFEVVFSSRIPSIVREEFRPLLEQFLAQHGLSQADLGRYLLHPGGAKVVQAYQESLHLADADLAVSRAVLREYGNMSSATIFFVMQQALAAQPLAKDEYGLLAVFGPGFSAELGLIRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E1</accession>
    <name>A9B4E1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0046"/>
    <dbReference type="EnsemblBacteria" id="ABX02698">
        <property type="protein sequence ID" value="ABX02698"/>
        <property type="gene ID" value="Haur_0046"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0046"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051820_1_0_0"/>
    <dbReference type="OMA" id="YVYETRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-46-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="35273" checksum="C3A601FDF162E82C" modified="2008-01-15" version="1">MEEQPTKPVKDGLIAQSYIPTDQIATVLYLADRLEKPLLAEGPAGVGKTELAKAWAAATGRELIRLQCYEGLDETKALYEWEYAKQMLYTQLLRDKLNNLLSDADSLRSAADRLAAEEEVFFSQRFLLQRPLLKAILNPKPTLLLIDEIDRADAEFEAFLLEVLSDFQITVPELGTLKAAHRPIVILTSNNTRELSEALKRRCMYLFIGYPSLEEELRIVEMKVPALGAKLARQAVEFVQRLRNLDLKKSPSISETLDWARALVLLNAKQLDQDILDQTMTVLLKHESDLQRTQRAIQTGRNRNDEGRRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z5</accession>
    <name>NUOB1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit B 1</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit B 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit B 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoB1</name>
        <name type="ordered locus">Haur_3080</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B4Z5"/>
    <dbReference type="SMR" id="A9B4Z5"/>
    <dbReference type="STRING" id="316274.Haur_3080"/>
    <dbReference type="EnsemblBacteria" id="ABX05718">
        <property type="protein sequence ID" value="ABX05718"/>
        <property type="gene ID" value="Haur_3080"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3080"/>
    <dbReference type="eggNOG" id="COG0377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_7_3_0"/>
    <dbReference type="OMA" id="AGWVRKS"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000376254" description="NADH-quinone oxidoreductase subunit B 1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <sequence length="179" mass="19604" checksum="B0FCE3AC71D395C8" modified="2008-01-15" version="1">MGLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLELMRASPRQADLMIVAGRVSRKMAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGVDEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHADGKPIRIEQAERGALKPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B528</accession>
    <name>A9B528_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Haur_3529</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 14">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3529"/>
    <dbReference type="EnsemblBacteria" id="ABX06165">
        <property type="protein sequence ID" value="ABX06165"/>
        <property type="gene ID" value="Haur_3529"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3529"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005373_0_0_0"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3566-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 14 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 14" id="KW-0639">Primosome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SF4 helicase" evidence="16">
        <location>
            <begin position="174"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="15">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="16">
        <location>
            <begin position="528"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABX06165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="593" mass="66067" checksum="EF25CD4369EDFBE5" modified="2008-01-15" version="1">MDKSLPADINAERATLGSILLDRDAIIPVAPWLASDYFYLEKHGLVFNAQVACYNRRVPPDLVNVTDELRRKDQLEVVGGVQYLLELSNSVPTSVHVEYYARIVERTALLRRLIIAGGKIAALGYDETQELEAALDQAESELFAVSQRRTADGFIHIGAVVDSFFEQISQMQERGGEVVGLKTGFTDFDKLTGGLQRSDLLILAARPATGKTSLALNIAYNAAKESEACVAIFSLEMSRDQLMQRILATETGVDMQKLRTGQIRDSDLQLLTEALGKLSTMSIYIDDSPGASIMDVRSKCRRLQAEAGIDLIIIDYLQLMQGGGKRDGNRVQEISEISRGLKALAREINVPVIALSQLSRAVESRTTHVPMLSDLRESGCLTGDTQIYLPDQGHYVRIDQLVGQQGFNVLALNQATWKLESWPVTHAFTTGTKPVFKLRTKLGRSIRATVNHKFLTIDGWQRLDQLHQTSQIAISQEIAHELGSNSQPTAIEWETIISIEPDGVEPVYDLTVDTLHNFVANNIIVHNSIEQDADIVMFIYREELYDPETDKKGIAEIHLAKHRNGPTGIVPLRFFRSTTKFSNLETYRQPEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G6</accession>
    <name>A9B5G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0139"/>
    <dbReference type="EnsemblBacteria" id="ABX02791">
        <property type="protein sequence ID" value="ABX02791"/>
        <property type="gene ID" value="Haur_0139"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0139"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_0"/>
    <dbReference type="OMA" id="RHIIARR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-142-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="452" mass="49552" checksum="C69EAADA2EF467AC" modified="2008-01-15" version="1">MSPINLFKEFPVTDLLTTIPGPRATALVDRDTAVMAPCSGRVYPFVMDRGLGCEVWDVDGNRYLDLNAGIAVVSTGHSHPRLVQALQDQVSKFIHMAGTDFYNEPMVKAAEKITSLMPGSGEWQVFFANSGTESVEAAIKLARYYTKRQNVIGFYSSFHGRSYGSLSITASKPYQRKGFFPLMPGVFHAFYPNPYRTPWGVEPERVAEICLDFIEKTLFTTTTPADDVAAIIAEPIQGEGGYVVPAPGFWQGLRDLCDRHGILLIADEVQSGVGRTGKMWAVEYEGIVPDIITSAKGIGSGVPVGAMVARKEISSVWKPGAHGNTYGGNALAMRAVYETLCLAEEELMANANEVGGYFKQRLHELEDRYECIGDVRGRGLMIGMEFIKDNVNKDPHGDLSNAVMEESFRRGMLLLTCGKSTIRFCPPLVLTKDQVDEGINLLNDTLQALGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R5</accession>
    <name>A9B5R5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1655"/>
    <dbReference type="EnsemblBacteria" id="ABX04298">
        <property type="protein sequence ID" value="ABX04298"/>
        <property type="gene ID" value="Haur_1655"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1655"/>
    <dbReference type="eggNOG" id="ENOG502Z8Z4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_487325_0_0_0"/>
    <dbReference type="OMA" id="CCNTDER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1679-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary amine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="SSF49998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735297" evidence="1">
        <location>
            <begin position="24"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="583" mass="64480" checksum="0E9282BF60A4C482" modified="2008-01-15" version="1">MQRSVLYRLLLLMMLSACGTTPAQHPTTTSVAAETPAILAAEITPEAQNYPLLTAYQQVINQALTATPPVLTLGSLDSQQAMAQIVALNEPKLQSQFVDQTGTPFRNEVFGVVPVRESDIIEATAACLQVSCYRVEVYNFALNLTLAITVDVSNQKVIVVERLANSQPDIPEYLTAVAREIASNAAEVEQALGYKPTSDQAVMANTKTALNATRCERSIHLCVAPTFVAGERALWAIVDLTDTRLVGVRWTNVGATGPAVTEKGMQNEAVLKYCDHTTRLERDGWAFDYMLTSSDGLRISDVSYQGKPLFKSAKLVDWHVNYSERDGFGYSDAVGCPYFSQAAVIAVEPPMIGEIRENDQVVGFQLVQEFWSELWPEPCNYYYEQAFYFYFDGRFRPAIASVGRGCGDDGTYRPVTRISLAETGTISAWNGTQWQAWQTEQLQGADTRQINPDGAEYRLDLANGESYTIATGRGQFDDGGRGDQAYVYATLDHPERDEGESDMVTIGPCCNTDANQGPEQFIDNPPESISNQHIVLWYVAQLKNDDTPGSQYCWAESVLRRGVYIPEEYPCWSGPLFQPVRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T0</accession>
    <name>A9B5T0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FBP_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1670"/>
    <dbReference type="EnsemblBacteria" id="ABX04313">
        <property type="protein sequence ID" value="ABX04313"/>
        <property type="gene ID" value="Haur_1670"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1670"/>
    <dbReference type="HOGENOM" id="CLU_1842362_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1694-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032330">
        <property type="entry name" value="EF-G-binding_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16571">
        <property type="entry name" value="FBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBP_C" evidence="1">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="16117" checksum="8E91662397BB6658" modified="2008-01-15" version="1">MDEIDETALIFERSALRKLFRKAEDYELPLDIRLSQHGFYHWLAERTNRIYLVWHDGTQTRGIVFNMSAHAGKPFRQRQCDLCGQFVEVGDMISVRSLKGRQDAAYQATYSYICADLEDCRGSAISTGQLNHFLNKHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B650</accession>
    <name>A9B650_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3625"/>
    <dbReference type="EnsemblBacteria" id="ABX06261">
        <property type="protein sequence ID" value="ABX06261"/>
        <property type="gene ID" value="Haur_3625"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3625"/>
    <dbReference type="eggNOG" id="ENOG5033UD3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1419208_0_0_0"/>
    <dbReference type="OMA" id="TNEMIDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3664-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="30"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="21168" checksum="7EA67F55E569ED44" modified="2008-01-15" version="1">MIDFGPLKEGKLTLGELGASLSKQDLWDATDEMIGDLLGLLTDAVDADIVFVPSDPKANDPGASEEEKDMAWTFGHLICHVTSSNEEAALTALAMASGILPNERLRYETPWRDLQTLEQARQRLEESRRMCLSMLDAWPDQPHLEISKVLYEAWGPLNAHGRYFLGLKHLNDHVAQFHEVMRQAKAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B651</accession>
    <name>A9B651_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3626"/>
    <dbReference type="EnsemblBacteria" id="ABX06262">
        <property type="protein sequence ID" value="ABX06262"/>
        <property type="gene ID" value="Haur_3626"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3626"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="WGTYLVK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3665-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="27"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="338"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="372"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="588" mass="65774" checksum="92E7BFA3A66899B1" modified="2008-01-15" version="1">MKHLDQYRRLLAHLRPYPRQVFYAYGSTLLAVGLNIAIPQLLKQAIDEGIASGSSRALLITALIILGVAVVRVIFGFAQRYYGEWLSFRVAYDLRNRFYDAIQRLPFSFHDRSQTGDLMSRATSDITETERFVGVGLLELSSTMLLLFGIIVAMVVEDLRLTGLALLPLPVLLYATIRFGNTVEPLFTKIQEQMGKLSTMMQESLTGIRVVKAFAREPYELEKFDRDNGEWYNRRFAVIRIWGNSWPFFNFLVAISVIILLWIGGPQAMNGTITVGSLFAMISYVLLLNNPVQRLGFTVNLAATAVASSARVFEIIDTFDELADKADAHSLEHVQGNVKFEHVSFAYREGGRPTLHDISFEAKPGQVVALMGPTGSGKSTITNLIPRFYDPIEGRVLVDDHDVRDLAIQSLRQQIGIVLQDSFLFSSSIADNIRYGRPEASDEEVIAAAKAARAHDFILHFSEGYQTKIGERGVTLSGGQRQRIAIARALLLNPRILILDDSTSSVDTETEHLIQQALEQLMQGRTTFVIAQRLLTLKNADQILVLDAGNVVQHGTHTELLAQPGLYRTIYDLQLKDQEESLVEEQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P5</accession>
    <name>A9B6P5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1711"/>
    <dbReference type="EnsemblBacteria" id="ABX04354">
        <property type="protein sequence ID" value="ABX04354"/>
        <property type="gene ID" value="Haur_1711"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1711"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_4_2_0"/>
    <dbReference type="OMA" id="LWLCGDS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1738-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="entry name" value="PTHR46313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="501" mass="55940" checksum="67DF32F658B16C61" modified="2008-01-15" version="1">MDYDLIVIGAGIAGLSAAALLAKDGYRVLVLEAHIEPGGCASSYQRKRPNGEHYIFDVGATVFAGFRPGGAHYWLGQKLGLTWPIRPVNPAMQVWLPDLRVTRWGDERWIAERQRLCLSQAWEAEQFWREQEHLAEVAWRFAGRMPAMPPESLADLGQLITRIRPEMLGLLPALPRTVKHALNRHKVDDRRIRTFIDGQLLISAQSSHAECAWLYGAVALDLARIGTYYVEGGAWNLAKTLEQALLKAGGEIRYRQKVSQIQTDLGQVVGVTTEQGERFRTKQVIANTTVWDLAELIDQPPSWMLRRTIKAVPQGWGAATLYLGIDEAAIPQGLAEHHQIIANYDQALGEANSVFISLHPADDASRAPAGQRAMTVSTHTDVGRWWHWRQTDPARYRAEKIAMAERMLDTVALAMPSIRQHIRYQQIGTPVSFARYTQRKRGMVGGLPQWRSVSGLLSLGPQAARINGLWLVGDSTFPGQSTAAVTQSAIQVYQKIRRADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X7</accession>
    <name>A9B6X7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="8">GPR</shortName>
            <ecNumber evidence="8">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="8">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proA</name>
        <name evidence="10" type="ordered locus">Haur_3208</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3208"/>
    <dbReference type="EnsemblBacteria" id="ABX05845">
        <property type="protein sequence ID" value="ABX05845"/>
        <property type="gene ID" value="Haur_3208"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3208"/>
    <dbReference type="eggNOG" id="COG0014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030231_0_0_0"/>
    <dbReference type="OMA" id="PGVCNAM"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0521">NADP</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="9">
        <location>
            <begin position="5"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="45300" checksum="61E187CF56C7BFC0" modified="2008-01-15" version="1">MLEAMGQRAKLAARILARTTTAQRNAAVEAMAEELSLDRESILSANEADMRLGREAGLTPALLDRLLLNEQRLEAIANDVRTVAVLPDPVGEVFEQGVLPNGLRIEKRRVPLGVVGVIYEARPNVTADVAALCIKAGSAVILRGGKEITRSAGALVQALRRALERVDLPADALQLIDNPDRELVRGLLTLDRYVDMIIPRGGSGLHDFCRKTATIPVITGGIGVCHAYVDHTAPLEQVVPIIVNAKVQRPSVCNSLETVLIERSAAAKVLPRLGAALQEHKVELRCDPESLAILREAGSADWNLVSAQPADFGQEFSALILAVRVVDGLDQAIEHIDQFGTDHSDTILSQDPAAIERFLNEVDSAVVYANSSTRFTDGSQMGLGAEIAISTQKLHARGPMALRELTSYKWVVRGAGHVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z0</accession>
    <name>A9B6Z0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3221"/>
    <dbReference type="EnsemblBacteria" id="ABX05858">
        <property type="protein sequence ID" value="ABX05858"/>
        <property type="gene ID" value="Haur_3221"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3221"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454701_0_0_0"/>
    <dbReference type="OMA" id="RINDREW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3256-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="514" mass="55249" checksum="D65FDD4D7F290F01" modified="2008-01-15" version="1">MQQRINVGMNPTVAVRICEGSLRVIAHDLPEAWFDVDEDEISFRAQEGHLSIERCSDDLELRLPHGAVLTIDVVQGDVDLTGLSAVHTRQIEGDISARDVQTFESDSVHGDASFTKSAKLSLANIDGDLKIYENTDTVVIKNVNGDAKISQAHNLTIINVNGDLSASDLFGDVAITRVSGDATLRGAIKSLAPIHVDGDLKLGINWLPEQVYRASANGDVVLEVADDANLSVNGFVQGDVSGMGDREPGSISLTWGTGTARLELNVQGDLSIRGGAASHSHSKSVGGTSWNTNWNWNNDDFNRAIRDFTDDLASMGRDIAAQFREMSRDWRDGKGERTAERARQATERAAERAAKAAERMSVRINEREYRFDPERIERLKEQAKRAADEGISRAYEAIGQALGNIEKNIANPNAPRPPAPPAPPAAPHAPQAPNAPHRVSISEDDGSSSSQHVAYTGDTVRISPEQAAAAQAATAAPAETPAVDKTQERLAILKMVQSGKISADEAALLLEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B729</accession>
    <name>A9B729_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3260</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3260"/>
    <dbReference type="EnsemblBacteria" id="ABX05897">
        <property type="protein sequence ID" value="ABX05897"/>
        <property type="gene ID" value="Haur_3260"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3260"/>
    <dbReference type="eggNOG" id="COG0623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_10_1_0"/>
    <dbReference type="OMA" id="GILDMIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3295-MON"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="28033" checksum="015037BA0F45948B" modified="2008-01-15" version="1">MDLLKGKKALIVGIANDHSIAWGIAQALKQAGAELAFSYAGESLERRVRPLAEQLGVSFVQQCDVSDDAQIATLFERLGAEFGSFDILVHSVAYAKREDLSGRFVDSSRDGWRIAMDVSAFSLVALTKAAMPLLNPNASILTLSYYGAEKVIPNYNVMGVAKAALEATVRYLAADLGPDGLRVNAISAGPIRTLSASGIGNFRRLHRAFTNANPMRRAITIEDVGNSALWLCSELASGVTGEVVYVDGGYNVLGMSEEEQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B737</accession>
    <name>A9B737_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3268"/>
    <dbReference type="EnsemblBacteria" id="ABX05905">
        <property type="protein sequence ID" value="ABX05905"/>
        <property type="gene ID" value="Haur_3268"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3268"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_3_2_0"/>
    <dbReference type="OMA" id="APIKVYM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3303-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04623">
        <property type="entry name" value="CBS_pair_bac_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044725">
        <property type="entry name" value="CBSX3_CBS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="74"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="15607" checksum="C671806F2F7750F2" modified="2008-01-15" version="1">MKIKHVLATKSPIIHTITPQAPLSQAVAILSEHNIGTLVVMEDDRIVGIISERDIIRAAAQDPAIFERQVQHVMTANVITGRPSDDLKAVLQTMTNRRFRHLPILDGDILLGIVSIGDVVKAQLGEYEGKLDTLETQIIEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B754</accession>
    <name>A9B754_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3701"/>
    <dbReference type="EnsemblBacteria" id="ABX06337">
        <property type="protein sequence ID" value="ABX06337"/>
        <property type="gene ID" value="Haur_3701"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3701"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014042_0_0_0"/>
    <dbReference type="OMA" id="VMDVFDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3743-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="394" mass="43438" checksum="B4E871BAE9363297" modified="2008-01-15" version="1">MLRFILKPDRDKSIRQRHPWVFSGAVARRSGPVHPGETVDIISSEGVWLARGTASTHSQMVARLWTWQRDEELDPSFIRQRIERAIKGREQLHNDPQTNAYRVIFSESDGLPGLIVDRFADWLVVQLLTQGAVAHTAIIVAALAELMPVRGIYERSDVEIRAREGLGEAEGLLWGEAPPDQLTIRENGYEFVLDLAGGQKTGWYVDQRINRQRVAQYAKDAEVLGVFSYTGGFEVLAAGAGAQSITAVDSSAAALRGLHTNLSQNGLNTPVTAVEGDAFKILRQLREEGKQYDLIVLDPPKFAHSQSQIDRATRGYKDINMQAFHLLRPGGVLATFSCSGLISADLFQKVVFGAALDAGRDAQIIDTLTQGGDHPVLLTFPEAAYLKGLICRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T4</accession>
    <name>A9B7T4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1819"/>
    <dbReference type="EnsemblBacteria" id="ABX04462">
        <property type="protein sequence ID" value="ABX04462"/>
        <property type="gene ID" value="Haur_1819"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1819"/>
    <dbReference type="eggNOG" id="ENOG502ZMAF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_815784_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1847-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="35804" checksum="FB36E12ED281696F" modified="2008-01-15" version="1">MPSKIDPNDWDANFSAKGPRQQGPLGVLLQTLLVLGIAGGLGYGVWLLNETMSEQNAANAATATAVAPTIFARATQRSIQATQDAIPTATPNLPIGRSLATSGLRFEPNERSQSKGNVNPNDSLQYIESREVGGVLWWNVRLFERANMDLPAAELGTSGWVLATTVTEPSAPPPVVADSTAVPAGPVDLPTTPIDPSSVILTRNANTNMSVSHPQAWTEYVIGENLAVFFSTAVDGEQGILANKVIGKNNDVAGIQAAIEETINILAAPNSQREYAINASEGTVKFVRVVRGQEAKIQAFVTVKPGPGGSLGVIVGFVPESGFAANQAILQQMTRSAIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T8</accession>
    <name>A9B7T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1823"/>
    <dbReference type="EnsemblBacteria" id="ABX04466">
        <property type="protein sequence ID" value="ABX04466"/>
        <property type="gene ID" value="Haur_1823"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1823"/>
    <dbReference type="HOGENOM" id="CLU_3008107_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1851-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025844">
        <property type="entry name" value="Herpeto_peptide"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14409">
        <property type="entry name" value="Herpeto_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="55" mass="6050" checksum="AD91FFD74842DCBF" modified="2008-01-15" version="1">MEFENIKTEELPAIFGLTYLEEEAAEINDVVGCLMPIDGYSGTSCDDSDQGYDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7V2</accession>
    <name>A9B7V2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Asparaginase/glutaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparaginase 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1837"/>
    <dbReference type="EnsemblBacteria" id="ABX04480">
        <property type="protein sequence ID" value="ABX04480"/>
        <property type="gene ID" value="Haur_1837"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1837"/>
    <dbReference type="eggNOG" id="COG0252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019134_1_0_0"/>
    <dbReference type="OMA" id="RKNHTSR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1866-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08964">
        <property type="entry name" value="L-asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004550">
        <property type="entry name" value="AsnASE_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparaginase" evidence="8">
        <location>
            <begin position="3"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="9">
        <location>
            <begin position="204"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="3">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604550-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="34633" checksum="A258DAE33F36C5D3" modified="2008-01-15" version="1">MHNVVVITTGGTISTKRTPQWSGAVPMLKGDDFSAMLPRGEFNVSFQDFTNLPSSHITPTMALDLAQRVNSLLLGEADGVVVTHGTDTLEESAFLCDLLIDSNKPVVFTGSMRIATDVGYDGVTNLTGAIRAAAAPQSRGLGVMVAFNDRLFSASTVQKIDSQTADAFDAPGFGPVGSLTGATVRIHHQPSGRQYIPCSRLAERVDLIYATQGADDRQLRAAIDTNSQGIVIAAFGGGRVPPWWLPTIQEALNKRIPVVVTTRCLKGICYDEYGYVGEYHDLKRLGVMFAQQLSPVKARIKLMVALGAAAHPQELREWFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B803</accession>
    <name>A9B803_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3300"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05936">
        <property type="protein sequence ID" value="ABX05936"/>
        <property type="gene ID" value="Haur_3300"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3300"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_40_0_0"/>
    <dbReference type="OMA" id="IAYVHYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3337-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="208"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="42690" checksum="3B993433422EAC60" modified="2008-01-15" version="1">MRVAPKIAFIRKGRWPLANVRTAEALRAQFPEYELREIDLIPIIRRKPALVALNGWWTLRQYAGDLAMRRRGPKDAFLITSYIFRAVKHLVADLLRDDDYLFSFQMQSLFDASVPNIPHFVYTDHTLLANRQYPGFNPASLYHPEWMKLEPTIYQNANLVFTRSNHVSRSLVEDYHCDPAKVRCVYAGSNAPVISEPPDPARYASQNIVYVGIDWERKGGPELLQAFAQVRAVYPNATLTIIGANPQTNQPGVEVIGRIPVEQLPHYYQRAAVFCMPTKLEPFGIVTIEAMNYWLPVVSTNLGAMPDFIEHDHNGYLVEPGTVDQLATALIKLVGDPERCRRFGARSVEIAARYRWESVGSAMREAIIQNIEHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B824</accession>
    <name>A9B824_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3321"/>
    <dbReference type="EnsemblBacteria" id="ABX05957">
        <property type="protein sequence ID" value="ABX05957"/>
        <property type="gene ID" value="Haur_3321"/>
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    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-3358-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Wzy_C"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="381"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        <location>
            <begin position="752"/>
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        <location>
            <begin position="989"/>
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        <location>
            <begin position="721"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="1141" mass="125561" checksum="2AE39226E6C6DBD3" modified="2008-01-15" version="1">MPLKESALDSRETTISLWSRRVMEACWLLALAMIPVYFSLLSDRHFEPDKAVALRSIVMILGGAWIINWLERGQVFRSWPRWRDWWRSPLVAPAIVYVGVFFFTTLTSVLVFTSFFGGYNRLQGFYTNFSYVVVFGAMLAHVRRREQLERIITVIIATTLPTLGYGWVQYQRSDPLPWAGDTAARVASSMGNSIFVAAYLILTLPFMFYRLITSVMATKRAESEATNSVGLDAAWFVTLGLIPLGQLSLLYATLKLGALLQAPLLGIGHWWIFPMSVIVVGSTLPLISWVTSTRSRSDWRLYLPGGLILLYMLSLVLGGYLTADQCQGTISETCYNLDMATAKRASDFRTWFLLAMAAYFGFYGLVLALPRRSEAAAHAIVQWLSAAIYAGLSLFTIVIIFFTQSRGPQIGMFVSIFVFFTLFLLQGLRSTSFKRIFGAALSAWVVLALAGAAFLVVLNTDSSSFSGLRQSNRYISRLGNLLETDGGTGLVRVLIWRGDEHTQGAVGLALSDPLRTVIGWGPESMFVAYNPFYPPRLANYESRGASPDRSHQALLDELVTKGAIGLFSHLFLFGSFLIIMLRLLCIPRLINLGLTSLLMLGIGIFFAVFLKSLALGLIAGSVGLLVVGLATWLGYAKPLEASLSFTWQLLIITVLSAVAANFVENLFGIPIVSSLLYTWVIMAVGILAGAHAGAYQLGTKPVVVAAPVVEEAAESTPAKAGTKRQAAQNARRTPAGRGRTSSGVTGAAPARILYAVVVPIVLLLVWFLNLDNIFADMRYLQGKQFIDQGQGLDQHLLGFAAIQDAVEHAPNEDLYFLMYGRALMTLATDLSIEQNKLVSENQNAAIAQVLNSRPRPDAELADLPDAEYSVAGLQTVARDFLTKFGPLQVLDYARLALEEAQRLNPQNKDHPANLGRLHSSWFRNTEQSDPEGARMHLDAAIEAYKQAHTVAPQDVELTGQWAMLYLYRQEYDTAIAELTKATTLDPLWSLNFIRLGEAYRRKGDLPNAALAFANALALDPRALSSSGLVDVAELPAERTARVQATFASMQSDPAVFDSFLTGFERAIASKPGDMSYRQIYTQVLSDSQRYDAGLTQVQLALAEMDKMGAADPTFNTTYADTRTAFEKLVSFFQSQLGQSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B844</accession>
    <name>A9B844_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC-C motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05977.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX05977">
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        <property type="gene ID" value="Haur_3341"/>
    </dbReference>
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        <property type="entry name" value="SEC_C_motif"/>
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    <dbReference type="Pfam" id="PF02810">
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    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX05977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36739" checksum="7CCFE5A85782EA0F" modified="2008-01-15" version="1">MAKVGRNDPCPCGSGKKYKQCHEAADRAQEDQLRLLRRAQDRLFPKLIDATQSDELALSMPTLFEQYWGGRYTAADMSELDELEDRGSERFLTWLAFDAQSGDDGSTLVERIAANPPAELELDEHELNLLPTWAGIRLRPYLITEIIKGKGALIQEVLTKETFTLRDHAAAKRLEENELIFAHLVPVGEEYYIAGAAAQTTPDTVEKLSEFLAVSLEAWQLRNPEADLNQFVRENSYLFNHFISVLPREAKEPSRFDDLMLRGRTALLMTKQSLGIGNDDDDDDDEFDDQADDDQVDDDDDQADNDQPDDDQPETLTDSDQQPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B851</accession>
    <name>A9B851_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Haur_3348</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3348"/>
    <dbReference type="EnsemblBacteria" id="ABX05984">
        <property type="protein sequence ID" value="ABX05984"/>
        <property type="gene ID" value="Haur_3348"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3348"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_5_0"/>
    <dbReference type="OMA" id="FAIPSMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3385-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="23"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="450"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="542" mass="60398" checksum="2DE1FCE7B88FDE13" modified="2008-01-15" version="1">MLRGLMMDYPLTVDRLLDHAYKLYPHKRVTTKQPDGSIHRYSFADLYHRVKRLGNVLHKLGINQGDRVGTFAWNNYQHLELYYAIPCAGAVCHTLNIRLSTEQLAYIINHAEDKVIFVDATLLPLFSKLADNIPAVETIVLINAQPGIETPFPNVLHYEDLMAQVEAEFDWPVTDERQAMGLCYTSGTTGNPKGVLYSHRSLYLHTMGENQATALAFTPDDIVMPVVPQFHAMAWGLPYSAMFAGADLVMPGLHLNPVALADLIADEKITFPAGVPTIWTAMYQELRANPRDFSHVRCLAVGGAAMPRGLIEAYERDFGVPVLHAWGMTELSPLGTISSLQPQHRQLSDHERWDLRAKQGYPIGGVELRIVNDAGEELPWDGTTVGELQARGPWVTAGYYKVEPTAEHFTADGWFRTGDVATINHEGYLGITDRTKDLVKSGGEWISSVELENTLMGHAKVTEAAVIAIPDERWSERPLACVVLTKDAGEVEPSELLEYLEPLVAKFWLPERVVFVSEIPKTSVGKFDKKVLRARYANGELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B879</accession>
    <name>A9B879_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06432">
        <property type="protein sequence ID" value="ABX06432"/>
        <property type="gene ID" value="Haur_3796"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3796"/>
    <dbReference type="HOGENOM" id="CLU_1459430_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3838-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="21016" checksum="978C78AAEC6C45EF" modified="2008-01-15" version="1">MPKFLHKFGQPRLIWLAFGVAMTQLVISNLLASLFHSWTRGYGLLDLGGGANAFSAKSSVTADLAYQLISNYGEYRSSHVWLIVPDMLLPIGVWLFFGLALLRLTRDVHGWQQWLPALASLYFFADYAENSCEALMLLQYPTQLPTVAMLWTWCFTLKNLAVGLNIGAIVLIFLWRWRQAQSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D7</accession>
    <name>A9B8D7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06490">
        <property type="protein sequence ID" value="ABX06490"/>
        <property type="gene ID" value="Haur_3856"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3856"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3898-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="723" mass="80405" checksum="14C4C025C5E93ADB" modified="2008-01-15" version="1">MLPTRSALRRMLLLLVIGHLAILGIINRAPIVAAHDSAALVDSTQFVTLSQPALNHLQTTQTITGTWNSRLANNLNIPGTITNLVFADDGRLTVLGDFNYLNGQLVNGLATMSQQGTWQGYGLHADDSGTLATAAYYHDQLYLGGRFKRLAGTPLNGIALWNGTNFAAVGSGVSRSDATTARVGQLGVMSDTLYLAGNFNRFNGQPTSGIIGWRNQQLVSIPSYPIDEVHGMKIVDDRMMITHTHPGEEPYVVSYALWQNDEWIEMPWPDFSQRYNFQWLFAGNDGFYRPIYSDSNRTHTQVQVWQTDQWTNSISTSLKFTYMSFTQLANQQIYVSDSKQLYQLTPAAWQLVNLPMQIRRIDTLANRNNLLYLAGDFTLNGQPSSLVRWDGTQLESLATTMRYANVASLGGQQGRPIAHTKDFNPFASYDQKLFTWNTISWQPLVHKITSQPFQVLSVDDQTSYFGSEHAITTTNNIARNLWQIQSNGTLSDVFGASTAISTWTISGSQLLGNLYGDFLKGVVLINQGQISNLAPYTYPLAIRDQVLMTGDQLYAVEPSGERGYWHTHFKQWDGTSWQEIAILGITDSQSRLQIVGWRGSLYFLEHNQLRRFNRTSSDLVATFDQVPNVLVADDDDFLYVGGPFASVDTVATGTLARWDGTSWQGLAQPANGEVTQISVNDRHLYLAGKFTHVGETPSLGVAALSFGPPENTTYLCYLPQIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8F4</accession>
    <name>A9B8F4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Undecaprenyl-phosphate galactose phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.6" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3873"/>
    <dbReference type="EnsemblBacteria" id="ABX06507">
        <property type="protein sequence ID" value="ABX06507"/>
        <property type="gene ID" value="Haur_3873"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3873"/>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024920_1_4_0"/>
    <dbReference type="OMA" id="EWQANGR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3915-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047360">
        <property type="term" value="F:undecaprenyl-phosphate galactose phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bac_transf" evidence="2">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="23582" checksum="CDB24D2C8C5142A9" modified="2008-01-15" version="1">MPAKPLAPSKRWFDLIVAGLGLLLLSPLLLLISLAIKLTSRGPIFYIRPRVGRDGHEFPFYKFRTMVLNAEGQGLGIEVAHNDQRITRVGQWLRRWSFDELPQLLNVVRGEMSLIGPRPSLPEQVARYTPDQRQRLAVRPGITGWAQVNGRNDIDWAARIQLDCWYIEHWSWRLDRLILWRTIGAILRPVGIYGRDGVAKDLRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H8</accession>
    <name>A9B8H8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07642">
        <property type="protein sequence ID" value="ABX07642"/>
        <property type="gene ID" value="Haur_5012"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5012"/>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_0"/>
    <dbReference type="OMA" id="PWCAMAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5075-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="32129" checksum="BCD76B6EE0CD147F" modified="2008-01-15" version="1">MLRIGAFSRIAHMTIDTLRHYDAVGLLKPAVIDPTTGYRYYTADQLQAVNQIVTLKELGFSLEEIAHIQKGHSSSADLHALLQHQLRVTEQTITAAEQRRSRIQAHLHAVEAQQRLPPYAIQLKSMDSTMVATMRATVPTMAQIPEYWQVWFQTVAAWLHTQQIPIGVPIAFHHDEGFQPEQIDTECGFIIPTIHRRAIAPPTPIVLRQLEAHAHIATVAVANPDPHTGGLKNAYAALGQWISTQGYTLYGAPREVYYGAPETGDVTVEIQFPVEQSQGIQPAVSRSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I4</accession>
    <name>A9B8I4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07648">
        <property type="protein sequence ID" value="ABX07648"/>
        <property type="gene ID" value="Haur_5018"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5018"/>
    <dbReference type="HOGENOM" id="CLU_1882897_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5081-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14889" checksum="2E747C654AD7B74E" modified="2008-01-15" version="1">MPLPSTTVRYLPEQNRYEALLEGASLGTFPKEIEATMAGHRARLQDLDDAPPPLAVLGADLHLAFQITDLRPMPAPVPQQYIATPLEALTATLILLNRNWLRATLAGRHADAQQIEAHEQCVRAQIHARLSANNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N5</accession>
    <name>A9B8N5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07699">
        <property type="protein sequence ID" value="ABX07699"/>
        <property type="gene ID" value="Haur_5071"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5071"/>
    <dbReference type="HOGENOM" id="CLU_993134_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5133-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="280" mass="32306" checksum="505C0E731A0E253F" modified="2008-01-15" version="1">MNNNYMLNRLDSISIDSDLQKNLYDIYMADSIRFSKRTALNVIYEIASSLDSYESSQECIAILNNAWHMMYGMIIRLDDIQDNQPIAPPFPNDIDLSTQYNILFSQYLIAESILDDLISNNLSIYRYVKIRRLWSDMMIRMSSGQYCDICSKNQPIEQDIAIKYQQIAQSKTGATYALAFGSIGIILFEDKSIYESLAVIGEIYGTLIQYGDDINDYESDMDKSVSFVDIVKKSESSPIHMYKYIYSIYYEHVELNMINFPDQLKNSIKGLFVKTFNIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q2</accession>
    <name>A9B8Q2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Demethylmenaquinone methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07716">
        <property type="protein sequence ID" value="ABX07716"/>
        <property type="gene ID" value="Haur_5088"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5088"/>
    <dbReference type="HOGENOM" id="CLU_072626_3_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5150-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="25654" checksum="AA643666FA6FF3DB" modified="2008-01-15" version="1">MIPDDVLKTGFAPLSTALIADACVRLDLPIRAAPATLQALISGSHRVGRAVPVRHYGSVDIFLDVLETTQPGDILVIDNGGRMDEACIGDLVVLEAQAAGLAAIIVWGVHRDTTDLLRIGFPVFSLGRFPVGPVRLDPWDDDATHVAQIGSVAVTRDDLVFADDDGVLVVAAVHGEQVLHTAHALWERERHQALAIHQGITLRDQVQFRAYLARRHTDPSLTFRQHLRQIGGAIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8R3</accession>
    <name>A9B8R3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07727">
        <property type="protein sequence ID" value="ABX07727"/>
        <property type="gene ID" value="Haur_5099"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5099"/>
    <dbReference type="HOGENOM" id="CLU_398891_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5161-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S74" evidence="2">
        <location>
            <begin position="554"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="690" mass="70235" checksum="3A25092DC5193F92" modified="2008-01-15" version="1">MGRIRIVALVFIVVLLGWFAPLYAQQSNDVIIQPHAFVGDTFTYQGLLMQGTTYPSGTFDFQFSLYDDPTAGTLLGQLQQDDVPVEAGQFTVALTFPEGSVTGHQRWLAIAVKTLNGSAYVPLNPRSAVSAAPIALSLPGLWTRQNDTSPNLIGGYSSNTVPANGVGMTIGGGGAFGNLQQIYDHYGVIGGGANNRVGSDDGTVTNDGYATISGGFGNTTTQEYTVIGGGQANTITGAFSTISGGTTNTIAHIYATIGGGMNNRVSAQFGTIGGGGSSASATGNRVYDTYSTISGGYNNVAGVDDTGNQPFATVGGGSSNNANALGSMVGGGRSNSISAIADYSVISGGYNNVATGLYATVSGGGSASSGQGNRAYDNYSTVAGGYNNVAGIDDSIGQPFTTVAGGGSNTASGYASAIGGGRLNQASGQYAFIGGGESNTATGDHTTIGAGRQNTANGNFSSILGGSGNSTSADYSVAAGENAVAAHRGSFVWASTQAAPDATITSTAPGQFIVRAPGGAWFGSSTQVDMPNGAILATDSGAFLSKGGTWSNSSDKHRKTQFAAIDPHALLTKLAAIPMQSWSYINEDPQIRHLGPTAQDFYAAFGLGTDDRHIATVDADGVALTAIQGLYQLNREQAAVITDLETRLAALETATPSPARSVWLLAGGWGSLLLIVGWLVGRRMRRGGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T7</accession>
    <name>A9B8T7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07751">
        <property type="protein sequence ID" value="ABX07751"/>
        <property type="gene ID" value="Haur_5123"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5123"/>
    <dbReference type="HOGENOM" id="CLU_004327_1_0_0"/>
    <dbReference type="OMA" id="DATHSEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5185-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="147"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="949" mass="107002" checksum="6D59FC7879EC7046" modified="2008-01-15" version="1">MADSINGSVDLDKSQVTGVIVGVNLGTIIYGRPPEEAERQRLVAYLDQVTKSHNTLRVVGVGSSHLASGIDLASAYMMLAVQGRQRVVRTLTAEEIAAHRQQRFEIPEELSADRCLPDHAVLAVAKRDGYLALLRAELATETVLAHPYLVLCGAPGSGKSTFAKHLVWALAQRGLDQINHHTGLLGWADKQRVLPVFMPLRTLAGALVGKDLGLNNTPHIGLLLDAVCAHLQTTYGLEQPRELLSAGLDRSRTVLLVFDGLDEVPLEATDHSLDRRSLLTYVRLFANAYAARILITCRSRAWTEEYGQITQWPMVELAPLSGGQMTQFIRTWFPLLHAKGLIDHEAIERYSDQLTQALRDPQRRRLRDMADNPLLLSMMIFVLARKGVLPRDRHSLYDDILKQLLGEWDTTSRNGQNLGQAVGDDRIMGDEVRDQVLDRLCYQAHLTATSTDGRGRIPSRELQFALMEYFARVNVADPYRAAERCIAYIDQCSGLLQPEDDGKVYAFAHLTLQEQSAGRHLVFYESLDQLLALRRDDRWREPIFLGVGCLTKVGLGSAKIDQLLTTLVDSDAYEAGTMHQYDWYRDLILAAELGADCDWGLLRGKQIKVDRIQRRLRAGLVNLLEDHDHSHAALAYHHGQAMEPAPLLVRERQKAAELLAGLGDPRYPVTIAQWQQETRDLSTQFGREGNHYWRYIPAGRYQVGGWDADEQSTVVELQDYWVGRFMVTVEQYRAFMEAGGYTNKDYWTEHGLQWKQREQRTEPRWWYDQTEQEYRNRPFYGVSWYDAVAYCQWLTDQLTPWLPQGYCIRLVSEAEWEVSAAYTADGQRQPFPWGEQPATPEHTVYNWSREKRPLSVGLGLVGQAACGALDSVGNMWEWTATRDEDNGGNGQQVLADSDDLMVLRGGSGYENSINVRCAARLRNPPGNGVTILGFRCILAHRTSVLNPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W1</accession>
    <name>A9B8W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_5147</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="10 11">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10 11">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07775">
        <property type="protein sequence ID" value="ABX07775"/>
        <property type="gene ID" value="Haur_5147"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5147"/>
    <dbReference type="HOGENOM" id="CLU_582365_0_0_0"/>
    <dbReference type="OMA" id="HSIGYNY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5209-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-0614">Plasmid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="328"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="469" mass="53689" checksum="CBCA3352F39A53DA" modified="2008-01-15" version="1">MVRPGVRLAFQFHASWCWRLFPMPDDTDIDDAVDALRRLQQLGLLDGTDAVVLHRLLAQVVQVQLGSTETLAVAEERIGRVVTWGNIRDEPHTLYPFVIHLRHVALRALDRADKIGLILVNSLALYERNIGSYSTARSLLEKIKETHSNLLVNDANIMEIITNNLAAVLCHQGLYSESQELYEGILRNLVNSNVNKDIYIVDIMNNLSIVLSYQYKYLEAKLLLEKAIRLYRKELGKSQDKLLATMMNNLASILEKQGIYHDSQSLYEEALIIQEQIFGPENPNTLSTKNNLALVLSLQGLHGEAESIWKHVLEIRKKVLGLDHVHTAQSMNNLGVAFEEKGSYNEAYELHISALNIRNHTLGQNHPDTIQSMNNLALVYARLGQYKESQQLYTQTLKWYQQQPSLMSTDDVRIMNNLAYVLENQKLYSEAYDLYQRVLVLTTHRFGIHSDYSQLIRETLDQLRPKISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W8</accession>
    <name>A9B8W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07782">
        <property type="protein sequence ID" value="ABX07782"/>
        <property type="gene ID" value="Haur_5154"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5154"/>
    <dbReference type="HOGENOM" id="CLU_240477_0_0_0"/>
    <dbReference type="OMA" id="TLHQMAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5216-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="64"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="841"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="860"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1596" mass="177605" checksum="C13F27CCA9D017C6" modified="2008-01-15" version="1">MTLILDLTMMDDGQATVTLDGQVLGTFDPHPLLAQRPLATPDADGLAYGDALYTALHGAAWPADWLMAPAPDPAAILAIRSSDPVLQAIPWEWLRIEGRWAITETLFIRLVPMTERMQAQLAANRPDGTQPYRLVVQCCEPLLWYRDEQWQPLDALPASLLVTPLAQEVQRATPALPVIWHDLAPTMNALLRTIPAHREPLLYHFTGHGDWHDGRPVVLFDDGSGRADPKDMALLSQRLRPRTQLAFVNACHSAEAQGDTASLAFQLCQQGTPVVIGMDGPVEDRHGQQWATDFYPSLLRGSDPPTALWDARLAMQDRERHHPAAWVQPVLYVADGYQWQPSTVTVPAPLPAVRIVPPVISDLQVAQRGFIGRRTELIEVADLVAQHPVVTVRGAGGMGKTALVAALAQRLAWRFRDGVYAYSFANQPSPDLMSVLRWCAGWLGLALDPAWQDADVQQQVIQQLRGKACLLVVDNYETILWALGRQDEGLDLWADADPADSAAEPRNERQQAAHAIQTFWEQVASLGIKVVFTTRHSPVRLEGIAEACYPSDDRIGQLQGLAEADAVALFERWCGGTALPHDPPPRGIVLQIVRLIGAIPLVIQLTARRWATLPNPQPDQFLTDLHTHLVAAQTMDGARHQQSLVVNVRLSVDALAPTMQAALFQLSLLENPLIWGLNAAAIWGLTTETEEGICYETDPAIARLHQLEATSLIQVVAAEQDVFGFQPALLQTLRYLRDHPPLRERMTTPMQDAQTRYGHYAWLTTKDYARQQEAGMLTKEAQAKFPDLLAGRQYLEPAQTGWVAYWVADIQRQFGLLGDAQRLHEEALQIAKSYKLLTLQSNVTYALASIHQIHGAYEEAEELYRESLALDDDLDDLQGRAANLHELATLAQLRGEYRDAEQLYRESLATHDMMSERESPFFTMYALAQIDAVRRAYEDAERLYHESLAIHDEPVTLAQLRGEYENAERLYRESLATYNAVSKRQHAATLNALAQIAVVRGSYEDAERLYCESLAIHDALGNRKSRAATLYGLAHIFIVRGAYEDAEGLYRESLAIADDLGDLQGRAAILHELATLARVRGEYRDAERLCYESLAIDDALGDRKSRASTLHELANLAQLQDMYGKAEEFYYESLAIKDALGDRKGRADTLHELATLARVRGMYEKAKELYCESLTIYDDLDNRQGRADTLNALGRVAVVLGAYEHAEELYRESLMIYNDLGNRKGQADTIHGFANLAQLRGVYDDAEGLYRESLVIYNDLGDRKGRADTLNALAQVAVVRGAYEHAEELYRESLAVTEALDDHKGRVSTLNALAQISVVRGSYKDAERLYRESLAITDMLDDSYAKARITVMLGQLLLKQGSNIGTTMIEQAYEIFHQLGAANDAEQTKTILELVQHPTLIECINQWMTSAREATGLTTLLNRVCQTVVAVMKTTDPEARQQVVEHLEPLVATDSLPIDGAMSFLQTLQAWLRGDETQWQTLLPQLNDRFQSVITQMQLAVHPIYRQVMPLLWATADALHRNDPAVTDQLVARLSTMSDQAAEGEPEDSPWMDAARALRAARAILQGDAIETTGLGEIYQAMLGQLHAIAANRPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD1</accession>
    <name>A9AUD1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0399"/>
    <dbReference type="ESTHER" id="hera2-a9aud1">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03050">
        <property type="protein sequence ID" value="ABX03050"/>
        <property type="gene ID" value="Haur_0399"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0399"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982696_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-402-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="32786" checksum="7CF79290AD3581A8" modified="2008-01-15" version="1">MRQFEYEQLISAADCQYCYQAMLERYPLQRVTINGHTWEFCDTGGDLPALLILPGGLARADLAFRWLSRCHQRFRVISLTYPNTILKLADLAKNLLALFGHLQIEAAWIVAGSYSGLIAQAVLHYCPQLALGLLLSDTGVPRRTRWIWLTLLQPLVAILPLGLVRRLFWQGTQQFLQPMADSLRPFWAERLHHNIQQLQRYDYLCLLNWWRELDWHLGAARWHGKLAIIVAEHDGLFGQRDQQLLRQYYPAASYQLMAHAQHCASLAQIDHYIDWALAWIEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ8</accession>
    <name>A9AUQ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1942"/>
    <dbReference type="EnsemblBacteria" id="ABX04585">
        <property type="protein sequence ID" value="ABX04585"/>
        <property type="gene ID" value="Haur_1942"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1942"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_451785_0_0_0"/>
    <dbReference type="OMA" id="WWQIENI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1971-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021280">
        <property type="entry name" value="DUF2723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11028">
        <property type="entry name" value="DUF2723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="580" mass="64853" checksum="39A564A53B5C335C" modified="2008-01-15" version="1">MQFVIQQSKLNVKTSSLFVFGLALLLYTITLLPGLGGGDTAEFQRVGPTLEVAHSTGYPLYSILTWLWSKLIPLGSIAWRVNLFSAFVAALSLSSFNQLAQTSGLAQRWALAGTAMLGLSSSFWQQATQAEIYAFAVLLQVSTLGLIVAWWQQRIPFWLLGLAAGLMLGHHRSSVFILPWMLIACCWQQRPSVRQWLLAVGAGCLSFLPYLYIVWRAPAWQNGWALLTDYLLGSAGGAWFDPQRALDQGWQRLFEVQIQLFGPQLTWLGLGLAGIGWWQCWQKQRPLAIMLGGSYCSILGFCLVYFVDDLAVFGLGAYVAQALLIGFGLAALPWPRWGLGLACGISLWLAWQTWPQIHQSNTAQPEQLARQRLAEPLAANSLVIGDGWSIESLRYLQTVEQLRPDLEFSFQAEQQRIRDQLAQGRQIYALQAIPELGLQHRKVGDWWQIENIPQQFKQQVAIVWQNGIQLTGFDLPAQAQDQLLIGLRWQTSQQLPSLIRFIHVLDQTGQLVAQTDSPTNPSSEFWPLAQAQTDLLAVNLPQYLPAGNYSVIVGWYDLGGQRIALTPQQNTYLLGMVMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV99</accession>
    <name>A9AV99_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0529"/>
    <dbReference type="REBASE" id="16515">
        <property type="entry name" value="HauORF528P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03177">
        <property type="protein sequence ID" value="ABX03177"/>
        <property type="gene ID" value="Haur_0529"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0529"/>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_448182_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-538-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="609" mass="67945" checksum="5139FA796833ECA6" modified="2008-01-15" version="1">MSDSGYELSFSLNTLNHLSEGLYSNIPAVLSELVANAWDADATEVSINIRQDEIVIQDNGIGMSIEDANTKFLRIGHQKREDSANTISGRHVMGRKGIGILAIFGIANIAEVYSCKDGVPHGFIIRKGDIERGISSDVTLYRPSPVPQDDLSIESGTKIILREIKSSIVNAEKTLRTDLARRFTIINNNCNFSVIINNIPISDNDRDYLNKVQFLWYLGEESSKYADFFTKLKKSFEITNLVDGMSGITVKGWIGTVYRPSNIPTSHRTISIFAHGKMIQEDILIDITDAGVYRQYIIGEIEADFMDSDDEDDIITSNRQRIKQTDPRYLKLLQYVKADIMRVIASMWTNLRKEYPSKPKKEEVNDSSSSKDANSSEQENTNASSDSSNTTDASSDSSNTTDASSETNDGDVEDNSFFDDDIPEPSPPPKQEITTAFREMKNLVKNSNIPDQMKNIILYDIQQAAYAYKGTSFKACIVMLGAILEGVMLGTIQRTDVLEYLITLQTVPKPLSDLGPRNPKFADRTVLAQYIGTTFSFQDCKEIIELCVQGTNKLGVDILQTVRNSIHPGSVLKDMKQLARFNHQSAVGYIAKLHEIINLVILWNPPSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB4</accession>
    <name>A9AVB4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N6_Mtase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0544"/>
    <dbReference type="REBASE" id="16516">
        <property type="entry name" value="HauORF544P"/>
    </dbReference>
    <dbReference type="REBASE" id="20893">
        <property type="entry name" value="HauII"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03192">
        <property type="protein sequence ID" value="ABX03192"/>
        <property type="gene ID" value="Haur_0544"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0544"/>
    <dbReference type="eggNOG" id="COG0827">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009149_0_0_0"/>
    <dbReference type="OMA" id="VDALYGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-553-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="341"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1093" mass="124932" checksum="E51113BC41E1F07E" modified="2008-01-15" version="1">MYAQRVANFVQEYQRYINNSANEEELRSGFYLAATNALGIPNFTLERGRQDIRRNRVILEFKNKGLFRGQSTSLKFKEAQDQLINRYIPQQSLRDGRRPSDYIGVCFDGEHLAFTFVEPDQTVRVTKLLPFDEHSAGALVMALDVDDRRELTPQNVIDDFGPSSFIARQTLQALWHHLNVSLDMGVKRIHMLFTEWKSLFQQGTSIGTRGRQKLQAYLQSVGLPESADITRLLFVLHTYHALFFKLLAAEVVLTNAIIPGMTQTDFCFSTAGLPDRSLIKLLVDDIEESKVFRRVNILNFVEGTFFTWYTHEAPAGLIEAIRQIMQRLNLYRLSDLQLERTRDIVKYVYEQIVPEPLRHSLGEYFTPEWLVEFTLDRVGYQGSQILDQKILDPCCGSGNFLIHAIERYKQAAHAQGWDDSAILHGITNHIFGFDLNPLAMLTARVNYLIAISDLLKTSSAVEIPVYQADAVYIPKPRPDDPTIYRYDISTRLTGCPILALDIPVSLIHKQHLFARVLEEMEESINEHQHTSAFITHLKRNPEFCRVEDHLDWIPYLEKMFNDIQFLESRSWNRIWCRIARNYFASVAIGSCDIVAGNPPWVRWSELPQLYAEKIKPICDEYGIFSDERFFGGNELDISGMITYTVIDQWLDEGGKLAFILPQNHLQSQSSGGFRQFQIRETPLEVLQVDDFSEVKPFRRVGNRPAVITIYKGRATTYPVPYNIWKRITPTTISENVSYATAAENLLSIPHEAYALEDAGKRWSILPLGRFPLLSMLNGEDRSIEGRKGIVTDLNGAYFIRILGHGYRTGTLRFKTSPDQGQKPVPERTYEIEADLVYPLIKGAKNVQPFYATTSELAVIVPNKGINSSSMPSMSRLTYQGYPLAARYFQSLNRDVLIDGVGLLDQRSTWRTRMRPFLEKQYADNLADIPFYAIYNVGDYTFAPYKVVWAEMSGSLKAAVISDGLVPYIEQRKIIIPDHKIYFASFSSEKYAHFICALLNSSIIREFVDSFTIKLQVGTIFKHLRLPKFDLENAEHLSLVDLSITAHNTMNKTNGSGNIEAFIEQIDIIAVRLLAKFAATITDQLQQEGFNLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB6</accession>
    <name>A9AVB6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1964"/>
    <dbReference type="EnsemblBacteria" id="ABX04607">
        <property type="protein sequence ID" value="ABX04607"/>
        <property type="gene ID" value="Haur_1964"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1964"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_15_0_0"/>
    <dbReference type="OMA" id="LARCGPM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1993-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="150" mass="16805" checksum="243E6F38FE69E7B3" modified="2008-01-15" version="1">MQRHYIDRLVEDLFTLAPQLHRLVDLEVRRQLDGATSAAQLRMLNELQHGPQSLSSLARQQHVSPQAISELLPALVERGWIERIPHPQDRRQQLLQLTNAGLDAVRQAQTQAHKQLTAHVASLSEVELSIVAAALPALQRLLDLAKCADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF0</accession>
    <name>A9AVF0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1998"/>
    <dbReference type="EnsemblBacteria" id="ABX04641">
        <property type="protein sequence ID" value="ABX04641"/>
        <property type="gene ID" value="Haur_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1998"/>
    <dbReference type="eggNOG" id="ENOG5031IF5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118117_0_0_0"/>
    <dbReference type="OMA" id="PCPVPTE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2027-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="21122" checksum="CE32E86B7057DF9E" modified="2008-01-15" version="1">MEDQLIPLLRPMTIVPVANLIDQRNAVPAESGIYGWWFKTLPPQVPSAGCLQVDDWTLLHIGISPSGHNPKTTRHLRHRLNDHLSGGANRSTLRMSLGCLLSEQLNLCLAPHGASKYLTFGAGEQRLSHWLTQHTGISWMLHSQPWELKPIILKQYSLPLNINNNDHPFVATLKRLREQAKLQARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK0</accession>
    <name>A9AVK0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integrase domain protein SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2048"/>
    <dbReference type="EnsemblBacteria" id="ABX04691">
        <property type="protein sequence ID" value="ABX04691"/>
        <property type="gene ID" value="Haur_2048"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2048"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_38_0_0"/>
    <dbReference type="OMA" id="MQWQPPT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2077-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="99"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="21889" checksum="A4AAB35142D07B07" modified="2008-01-15" version="1">MTTALRRRMTEDMQLRGLSRATQQSYLYTIGLIARSFGRSPDQLTDTDLRHYFLYLRHEQHRSRSTIIRTLCALKFLYEQTLQRTLPSLELIRAPKEHKLPVVLCPEDIRRILVQIKVDQYRVCLAIIYACGLRLQEGLQLRVSQIDSARMVLHIRAGKGNKDRDVPLPASALQVLRVHWRTHRHPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR0</accession>
    <name>A9AVR0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4028"/>
    <dbReference type="EnsemblBacteria" id="ABX06660">
        <property type="protein sequence ID" value="ABX06660"/>
        <property type="gene ID" value="Haur_4028"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4028"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_0_0_0"/>
    <dbReference type="OMA" id="CALLSCW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4070-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="32109" checksum="2E8B6AE332D49899" modified="2008-01-15" version="1">MSILDLFRDYTLRNVALGAMVLGIVSGILGCFAVLRRQGLLGDALSHAALPGIAIAYLLTGSKAPIVLLLGAGIAGWVGTLVINRIVRDTRISEDSALGIVLSVFFGVGILLLTYIAKRNDANQAGLDRFLFGQAATLVATDVLTMSILGGLALGCLVLLYKEFKLLAFDPAFAASLGFPPNRLGILLTSLIVVAIVIGLQTVGVVLMAAMLVGPAVAARQWTHRLSVMLVLSGVFGASAGIAGTMLSLGQQHVPTGPMIILSLTAIVTISLLFAPARGLVWAKIRQNHSLNNEPRNREIQPAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW6</accession>
    <name>A9AVW6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0556"/>
    <dbReference type="EnsemblBacteria" id="ABX03204">
        <property type="protein sequence ID" value="ABX03204"/>
        <property type="gene ID" value="Haur_0556"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0556"/>
    <dbReference type="HOGENOM" id="CLU_1935152_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-565-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14381" checksum="7C6DEB320D45DADB" modified="2008-01-15" version="1">MAHTDGSIKAVMQEELLETATVLNWTDVSNAGYNAALRRTLRRLNLPNVAASANDPLLETVAIIEVWRSVVNATVTAINFEADGGKFDRKAMHDHAVRMLKQLEAEFVTNQPVVVEEAPMSGTLDTFSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ7</accession>
    <name>A9AVZ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0587"/>
    <dbReference type="EnsemblBacteria" id="ABX03235">
        <property type="protein sequence ID" value="ABX03235"/>
        <property type="gene ID" value="Haur_0587"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0587"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="QTCLEIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-596-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13660" checksum="9BA4C0CC267565B7" modified="2008-01-15" version="1">MAKTIFIMDDDLALQMVMEIALREVGYEVVLANNGVEGIAQLETLKPDLIISDIMMPEMDGVEAFNQIRERIQDEGIPMVIVTALNRKPWFSDLEEEGAVILQKPFEVDTFIDLINTMVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW15</accession>
    <name>A9AW15_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate/guanylate cyclase</fullName>
            <ecNumber evidence="5">4.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0605"/>
    <dbReference type="EnsemblBacteria" id="ABX03253">
        <property type="protein sequence ID" value="ABX03253"/>
        <property type="gene ID" value="Haur_0605"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0605"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_110_0_0"/>
    <dbReference type="OMA" id="FIDICGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-614-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="4">
        <location>
            <begin position="177"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="40008" checksum="5FA1DFB1DB2A0565" modified="2008-01-15" version="1">MTATQPRILVVDDSEDNRYLLQRQLLRRNYGVVLAENGQQALDYVQSHTIDLILLDIMMPVMNGFEVLQNLKQNEQLRHIPVIIVSAADDMENVVKGIQMGAEDYLAKPFNTTLLRARIEASLEKKRLHDQEQAYLQAIALEQAQSNRLLRNILPQTIADQLKDQQANIAEYFSSVSVLFADIVGFTELSGHINAKELVAWLNRLFSRFDQMTLDVGLEKIKTIGDAYMVAAGLPIAQPDHAERLALFATSMLAEIEQITMPNGKPLQMRIGIHSGPVVAGVIGTIKFSYDLWGDTVNIASRMESSAHPNTIQVSAETYALLQDHEHFSLQPRHGVEMKHLGTRTTYILNRHRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW36</accession>
    <name>A9AW36_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0626"/>
    <dbReference type="EnsemblBacteria" id="ABX03274">
        <property type="protein sequence ID" value="ABX03274"/>
        <property type="gene ID" value="Haur_0626"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0626"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_3_0"/>
    <dbReference type="OMA" id="HDAIAMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-635-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="22366" checksum="6EB3E601B6DDD764" modified="2008-01-15" version="1">MSPRRDVRVERTAQIIEAATRLFAQHGIDQTSMDMLAKAVGMSKGVLYWYFESKDAIILALLEQLFNQPLLEVQALLQAPESTAHRLSQLTTNLAAALEELQSLVPLAQELYALSARNNNVQSFLASYFQRYRASLAELIQQGLERGEFSSIDPEQVAWHLAALYEGSTVLWLLEPMPQRLTEQLQAALQLLLKAIVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW69</accession>
    <name>A9AW69_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C14, caspase catalytic subunit P20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2079"/>
    <dbReference type="EnsemblBacteria" id="ABX04719">
        <property type="protein sequence ID" value="ABX04719"/>
        <property type="gene ID" value="Haur_2079"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2079"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_376327_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2107-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="737" mass="81941" checksum="1FD1AA47E61ACD85" modified="2008-01-15" version="1">MVAQLILKHHLTVSYFPEESYPAMKGEFARILDELSKQGIHETIYLDGLDQLQPEIDGSRDLSFLPPQPPQGMVIVLGSRPDETLKPLEILHRVDYDLPPLSETDALSLWRSVQPGMADGLFHDLYTALKGNALFVHLAADTMQDASVVDATSLIKQIEQNPQNLFGITLERIKRVPLSKWDTVWKPMLALLLVAQEPLRLDVLGDLLGHDHDTMQDAVLVLGGLVSQGIDHQVALHHLLFRDYLAASVFNDRDVKRWHQELSNWCAKDVDAIWSDDRDPIEQARRVYARHHYITHLSGAENWPTLWQVLDAGDYGEQKTRFDPSTRLYALDLDRGRESVIKAGQSTEEHIQNLPRLWKYSLLRTSLTSRVDQWPDNAFEVLVILGRTQEALERIQLLSDPEQQITLWCKMLAQCDTKNYNIILNRIQQSVSQLSRHHTDTLATIAETTATSGNIDRALSITAAIENNDRTGILKKIARTAATSGDIDRALSIAATIENDNSRSYALTAIAEAIATSGNIDRALSIAATIENDNSRSYALKKIAETIATSGDIDRALSIAATIENDNSRSYALTAIAEAIATSGNIDRALSIAATIENDNSRSYALKKIAEAIATSGDIDRALSIAATIENNDRTGILATIAETAVASGDIDRALSIAATIPDDRMRINTFITMAPVIQSAEKILSIIHKEWFQSKTHDMTLYSFCLINLLSENNLWLITTIIKSQGWVNDQLKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW73</accession>
    <name>A9AW73_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.173</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.173" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2083"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04723">
        <property type="protein sequence ID" value="ABX04723"/>
        <property type="gene ID" value="Haur_2083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2083"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_8_0_0"/>
    <dbReference type="OMA" id="ICPFFGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2111-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102203">
        <property type="term" value="F:brassicasterol glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102205">
        <property type="term" value="F:cholesterol alpha-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102202">
        <property type="term" value="F:soladodine glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="44473" checksum="674D10381565E963" modified="2008-01-15" version="1">MPTITIMTGGTRGDVQPYVALGAGLQAAGYTVRIAASDNFAGLVTDAGLTFVSTGESIEALLNSPPWRATLERGNFVTILRQMQREMRSRAAQQARQIPTIIHGSDLLIAGMAGFGGAFTAALAAQIPILIAHLFPFTPTRRFPSPLIPVATLGGMLNRLSFRVMQLVFWQTLHAADAATRTTLGLPAAPLGGPFGQYERQQIPVMYGYSPHVLPRPNDWPPQHVVTGYWFLDPPLGWIPPADLVAFLAAGPPPIYLGFGSMGGRNPEAAGRMALEALAQTGQRGILAAGWGGLTVRDVPPTVHLLEAIPHAWLFPHLAGIVHHGGAGTTAAALRAGVPSIVVPFMGDQAFWGKRVAELGVGPPPIARTSLRSVQLGHAIERVVRDAAMQQRAAVLGQQIDGDRGIPAAVAIVQRLVPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD3</accession>
    <name>A9AWD3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane sensor hybrid histidine kinase</fullName>
            <ecNumber evidence="6">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2143</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2143"/>
    <dbReference type="EnsemblBacteria" id="ABX04783">
        <property type="protein sequence ID" value="ABX04783"/>
        <property type="gene ID" value="Haur_2143"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2143"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_368728_0_0_0"/>
    <dbReference type="OMA" id="MSFMSAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2171-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="263"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="510"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="628"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="559"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="755" mass="83893" checksum="AEFED3F2AFFD0C1D" modified="2008-01-15" version="1">MQASIQRWLNTIKISDPVQREQAVLLQIMLIGLSIICFFTVPTAFIVSSTVGSAFRASLTSILILIFFVIAVMNLRQGHFRRSVTLASSGLVVGLSIILLLEGLRNSAWILSAFMMPITLSGLLTGRKGIKTIAGASIIVIAILGGLQLFNLQFVGAYPRLGDLLPPTISTFIFSVLIVGFFFHRFSASLNDALSRALQRESELQQIRDKLEILVDQRTAALQDALHAVEEREGRLEKTNIELAAAKTAAEEANQLKSRFLANMSHELRTPLNAIINFTAFLDRYGEFSERQRELQERVLYNADHLLGLINDILDLSKIEAGRMELMYEKTQLEPIITGVMATASGLTRDKGLELELDMPEELPTMVIDKVRIRQVLLNLLSNAVKFTEQGQINVTISQPDPETVQISVQDSGIGIAPEHQQQIFEEFQQVQNEVTHQYQGTGLGLPISKLLVEMHGGNMWLESTPGKGSTFFFSLPITNKLPETTTIDLTAPPSLAELEAEPSNPTTIEIVVIDDNPDAHETFRVMLESGGYRVHSVLDSRLAISTIKQIEPRLIITDVQMPNLDGWELLAQIKNDPTIAHIPIVVCSVVDQGTIGLVLGARKHIVKPVREEVLLAVVQECVEPTAEILVVDDNPDARQVIQHILAARDYAISEAADGIEAIAMIEQSKPDLVILDLMMPQMDGFEVLENLRHSPNYADIPVIIVSAKDLDQQEHDWLRTRAQGVIAKRQLSEEEFLRRINEIFNQGVEYARGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF1</accession>
    <name>A9AWF1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS</name>
        <name evidence="11" type="ordered locus">Haur_4078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4078"/>
    <dbReference type="EnsemblBacteria" id="ABX06710">
        <property type="protein sequence ID" value="ABX06710"/>
        <property type="gene ID" value="Haur_4078"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4078"/>
    <dbReference type="eggNOG" id="COG0249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_3_1_0"/>
    <dbReference type="OMA" id="TPMMAQY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="10">
        <location>
            <begin position="749"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="675"/>
            <end position="682"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="928" mass="103831" checksum="F7C819D737870A61" modified="2008-01-15" version="1">MSKMTMWQQYLSIKQKYADVILFFRLGDFYETFGDDAKLIAEVLDITLTVRGLSSDENTPMAGVPYHAADNYIEQLVSRGYRVAICEQMDEMVHKTLQKREVVRIVTPGTLTEPTMLQAERNSYLAAILVDRGNVGLAYADLTTGEFCATELRGNEALKQLEGELARLGAAELLVSDAPELRPAGMEIAKKQLAQDLAPMRKAERERLLPHERTAKKVEGNNESTWVQGNVTQWPNWHWDARTARDALLNQFKSQSLDGFGLGNKALATRAAGALIQYLHETQRDSVAQVRSLRVYDTTRFMFLDPQTRRNLELTEGAGGQRKGSLIAVLDQTRTPMGARLLRQWISQPLIELGPLTERQQAVSCFVEETLVRGELRALFKGVGDIERTINRVVQGIATPRDLVRLREALRLTPDILSQIERTGLRSTSPTEAAPSDDDLFDDEPTSNQIDACADICELLEQAIADDPPALLGTWDNARSDENVIRKGHAAEIDAIVEATRDAARWINELEAKEQQRTGIKTLKVSYNKVFGYYIEVTKASGETRIPDDYIRKQTLVNAERYITPELKEYESLILNASEALNEKERQAFRLILRHLANAGNRLLDLARAIAEFDVYSTLAEVAVRQRFVRPTLRLDDVFVIQGGRHPVVEHNLNEPFTPNDAHFDADHQIIVLTGPNMSGKSTFLRQVALIGLMAQIGSFVPADYAEIGLLDRIFTRIGAQDDIATGQSTFMVEMIETANILHNGSPRSLIILDEIGRGTSTYDGLSIARAVVEYIHNQPRLRAKTLFATHYHELTELANILPRVHNWTLAVAEEGDHVVFLRKVIEGAADRSYGIHVAQMAGLPPAVIKRATEVLSELEGKGDREQRREAMRRMNAAGSSAVPQMSLFASNEPNPAVELLREMDVTQLTPIEALTKLYELQRLAKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL0</accession>
    <name>A9AWL0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine carbamoyltransferase</fullName>
            <ecNumber evidence="3">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4137</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4137"/>
    <dbReference type="EnsemblBacteria" id="ABX06769">
        <property type="protein sequence ID" value="ABX06769"/>
        <property type="gene ID" value="Haur_4137"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4137"/>
    <dbReference type="eggNOG" id="COG0078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_3_2_0"/>
    <dbReference type="OMA" id="DGNNVCN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4183-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="154"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="269"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
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        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="35026" checksum="0A04AC36409F1E85" modified="2008-01-15" version="1">MTHPLLGRDLLALADWNDTELFDVLETAAELKLRQQRRKAHPLLANRTLAMIFEKPSTRTRVGFESAMVQLGGHGIYLSPRDTQIGRGETIGDTARVLSRMCDAIMARVNDHATLVELAQAADVPVINGLSDWLHPVQALADALTIREHFGSCQGVKLVYLGDPNNVSNSLLELAPRLGMDFAIGTPFVANVDQHLLAQARLQAAANGTKIIITNDPLEAVKDADVLYTDVWVSMGQVVAEGHLEALQPFQINAELLAAARAGAKVMHCLPMHRGEEISADIADGERSIVFDQAENRLHTHKAVLVATIAGLALRRTKRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP9</accession>
    <name>A9AWP9_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0652</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0652"/>
    <dbReference type="EnsemblBacteria" id="ABX03300">
        <property type="protein sequence ID" value="ABX03300"/>
        <property type="gene ID" value="Haur_0652"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0652"/>
    <dbReference type="HOGENOM" id="CLU_2395691_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-663-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="93" mass="10204" checksum="1635EFC5CBCAB0E8" modified="2008-01-15" version="1">MPRRLPADQITLFWQAYDASGNASAAGRIAGLSKDQAHRLLKKRGERPVATVTRAQLEAVLEQVETLATEVQAVRQRLVRLVALLPAPPISNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWT1</accession>
    <name>A9AWT1_HERA2</name>
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        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0684</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0684"/>
    <dbReference type="EnsemblBacteria" id="ABX03332">
        <property type="protein sequence ID" value="ABX03332"/>
        <property type="gene ID" value="Haur_0684"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0684"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="ERQRMTI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-696-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="33"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="348"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="382"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="598" mass="65350" checksum="CAD53E07BEFAB17E" modified="2008-01-15" version="1">MLAQAPKQLGNLRHLELRRMFQYVYPYRWRLSLALLCLAISSGIGLVMPLAIRNLVETVKDASSTAALDKVAIGLMGVFIAQMVFNYIQGYFLTYVGERAVADLRIEVYSHLQRLSLAFFSERRVGELTSRVTNDVTVIQGIGTNAVAAFLQNGITFIGSFIMMINLSWQLTAITLLLIPLLIVLAIIYGRRIRNMSTEVQDRMAEASSVLEETISGVRIVQSFAREPYEVERFSGAIEHAFSASMRRTKTRAQFVPIVSFSGFGALVFVLWFGGRQVLNGTMQLGDLIAFLLYAAVIAGSLGTFTSLYSQLQEALGSTARVFGILDTAPEIASKTNAINLPPIEGEIYLEDVSFNYGEAATPVLSNINLKVEPGEVMAIVGPSGSGKSTLVNLIPRFYDVTAGRITVDGFDIRDVDLPSLRSQIGIVPQETLLFSGTIADNIRYGNLDAPMEAVIEAAKAANAHEFISNFEGGYESIVGERGIKLSGGQRQRVAIARALLKNPRILILDEATSAMDSESEGLVQEALERLMQGRTTFVIAHRLSTVKNATRIAVIEAGKVTELGSHSELLAQAGTYARLYQLQFETNESAGSVLTEY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY7</accession>
    <name>COAD_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="1">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaD</name>
        <name type="ordered locus">Haur_0740</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial CoaD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AWY7"/>
    <dbReference type="SMR" id="A9AWY7"/>
    <dbReference type="STRING" id="316274.Haur_0740"/>
    <dbReference type="EnsemblBacteria" id="ABX03388">
        <property type="protein sequence ID" value="ABX03388"/>
        <property type="gene ID" value="Haur_0740"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0740"/>
    <dbReference type="eggNOG" id="COG0669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100149_0_1_0"/>
    <dbReference type="OMA" id="EFQMALM"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000096803" description="Phosphopantetheine adenylyltransferase">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <sequence length="165" mass="18214" checksum="374B2142F8C06AFF" modified="2008-01-15" version="1">MTIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAHLPNVRVDAFSSLVVEYALEIGATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMADQRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTHEESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX16</accession>
    <name>A9AX16_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2184"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04824">
        <property type="protein sequence ID" value="ABX04824"/>
        <property type="gene ID" value="Haur_2184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2184"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_0"/>
    <dbReference type="OMA" id="THWFWDT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2212-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30979" checksum="DF9304CB10820AFB" modified="2008-01-15" version="1">MGDIRYHQWKHEPLTEMPHISVVVPCFNEQERILPTIGAIMACFCTLGRPWELIISDDGSTDQTVAIIEELGFANINLLKAPCNQGKGSAVRAGIIAARGDFILFADADNSTPIEQIHQLLPLLETGAYDLAIGSRATIAAHTQHRSLVRRTMSATLRAIVHYGLQLDIYDSQCGFKVFHQSVAKHLVQLQTMPGFAFDLELLFLAKKYHYQIIEISVEWIDAPGSKVHPIRDTYRFIRDILKIQINNLRGRYAKPWLKARHRDNLPSKHWYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXA8</accession>
    <name>A9AXA8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="7">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4196"/>
    <dbReference type="EnsemblBacteria" id="ABX06828">
        <property type="protein sequence ID" value="ABX06828"/>
        <property type="gene ID" value="Haur_4196"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4196"/>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_1_0_0"/>
    <dbReference type="OMA" id="CEEEMKM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4243-MON"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="8">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="37430" checksum="C2737D87A49510B4" modified="2008-01-15" version="1">MKKIPVGVLGATGMVGQRFLSLLIDHPYFEVTVVAASERSAGKTLAEAGRWMIGGEMPSQFAKMTVQPVDQVGDVGLVFSALPSDAAGPTEIAWAKSGALVFSNAGAHRRDPLVPLLVPEVNPDHVNLLELQRQQYGWSGGILTNPNCTTTHAVLPMRALHDAFGLTKVLLVSMQAISGAGYPGVPSLDIIDNVVPLIKGEEEKVEWEPRKLLGTLGAQGVEEAQITISAHCNRVAVIDGHTECLSLAFERPPADEAELIAVLREFKAEPQALNLPSAPAHPILVTELADGPQPRRDRDAERGMATTVGRVRRCPILDYKLVLLGHNTLRGAAGGSLLNAELMVAKGLIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN7</accession>
    <name>A9AXN7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0803"/>
    <dbReference type="EnsemblBacteria" id="ABX03451">
        <property type="protein sequence ID" value="ABX03451"/>
        <property type="gene ID" value="Haur_0803"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0803"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_0"/>
    <dbReference type="OMA" id="GIGAWNE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-816-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="165"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="44267" checksum="C6AC850718EB741E" modified="2008-01-15" version="1">MTWIVLLALTTMIALLWGWRGQRNLRRELAYLRNRPVVAPTPSADPFNQLFRTLSAALDAGVIVVNDGRTIRYCNDVAAKLFGVSANAVVNHSVITLVRDYQADTMIEQSIRRRDPQQVTLQPVLSNRTIRIWCEPLPESGALILARDLTQLSLLERARRDLVANVSHELRTPLASIKLLVETLATQPPPELAQRMLGQVDTELDAVMQLVDELHELSQIESGRTALQLQPTPVEDIVERANDRIQPQAKRKDLRVAVTIAPDLPEVYVDRDRISQVLLNLLHNAVKWTDAGGTITIEAGLRSRSELGHHLSRMLEPSNRWVIMAIHDTGAGIPAEAIPRIFERFYKVDRARTRGVGGTGLGLAIVKHLVEGHGGVVWVASSEGRGSTFTVALPVVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR8</accession>
    <name>A9AXR8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0834"/>
    <dbReference type="EnsemblBacteria" id="ABX03482">
        <property type="protein sequence ID" value="ABX03482"/>
        <property type="gene ID" value="Haur_0834"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0834"/>
    <dbReference type="HOGENOM" id="CLU_1592316_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-848-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="167" mass="18303" checksum="53E830F737EFC9B2" modified="2008-01-15" version="1">MDCAACGRHNETAAVFCVYCGIRLETANQRKPVQPALGKTIDLRRESGPAVQSIPVTPKLEPVVPPMPVAQPIVQRERSGKSSNDGLVVLGLLVLGLLMFSNVAIESWQLIMMGFGVLVSRQSHQAAVWLIGIPILAITNWWWGIVLLVIFSNHKSHGCGMKHSYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT4</accession>
    <name>A9AXT4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ethanolamine ammonia-lyase large subunit</fullName>
            <shortName evidence="1">EAL large subunit</shortName>
            <ecNumber evidence="1">4.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eutB</name>
        <name evidence="2" type="ordered locus">Haur_2260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ethanolamine = acetaldehyde + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15313"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57603"/>
            <dbReference type="EC" id="4.3.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
        <text evidence="1">Binds between the large and small subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine degradation; ethanolamine degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EutB family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2260"/>
    <dbReference type="EnsemblBacteria" id="ABX04900">
        <property type="protein sequence ID" value="ABX04900"/>
        <property type="gene ID" value="Haur_2260"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2260"/>
    <dbReference type="eggNOG" id="COG4303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048555_0_0_0"/>
    <dbReference type="OMA" id="EADQNDM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2288-MON"/>
    <dbReference type="UniPathway" id="UPA00560"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008851">
        <property type="term" value="F:ethanolamine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00861">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010628">
        <property type="entry name" value="EutB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044939">
        <property type="entry name" value="EutB_dom_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044941">
        <property type="entry name" value="EutB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39329">
        <property type="entry name" value="PTHR39329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06751">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018788">
        <property type="entry name" value="EutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="1" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="463" mass="50145" checksum="0B59726D681E638A" modified="2008-01-15" version="1">MTSYQHSIRQRQYQFDSLKTLLAKATPERSGDALAGLIAASAEERVAAQWCLADVPLTTFLNEVVIPYETDEVTRLIIDSHDQAAFAPIRHLTVGGLREWLLDYRTDSQQLAAVAAGITPEMAAAVSKIMRNQDLIAVAKKCQVITRFRNTLGLAGRFSSRLQPNHPTDDPQGIAAAIFDGLLYGCGDAVIGINPATDSPQAMTSLLHLIDELRQRYAMPVQSCVLAHVTTALQVIELGAPVDLVFQSIAGTEAANRSFGIDLALLHEANQAARGLQRGTIGNNVMYFETGQGSALSANAHHGVDQQTCEARAYAVARAFEPLLLNTVVGFIGPEYLYDGKQITRAALEDHFCGKLLGLPMGCDACYTNHAEADQNDIDNLLVLLASAGCTYVMGVPGADDIMLNYQSSSYHDIRFVQTTLGLRPAPEFEAWLQQLGISDQAGRLIANERHRLLQSAAQLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU5</accession>
    <name>A9AXU5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2271"/>
    <dbReference type="EnsemblBacteria" id="ABX04911">
        <property type="protein sequence ID" value="ABX04911"/>
        <property type="gene ID" value="Haur_2271"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2271"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_0"/>
    <dbReference type="OMA" id="FQRTATQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2299-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="405" mass="45886" checksum="3FC4C437D813DF4D" modified="2008-01-15" version="1">MIHSTYAELFNQQFVQDPFPTYAALRAEAPIHRISLPDGRGLWMITRFEDVKAALKDPRFIKNWRKVLNPEEQKLMPVMPPVVQLLFKHLLALDPPDHTRIRGMVHKAFTPQLVEQLRPRIQQIADELLDAMLAGPRSTDLLTAYAFPLPLTVIAELLGIPLDHREKFRYWSGLVVTVDPSPDRFTRMAGEMEEFGNYLRELFAEKRANPANDLTSALVQVEEAGAKLTEQELFSLVFFLLVAGHETTVNLIGNGMLALLQHPEQLNLLRETPDLIRNAVEELLRYDSPVETSTIRWACEDLEFAGVKIPRGEQILAVITSANRDPQHFAAPDQLDITRTEHNHIAFGHGIHYCLGAPLARLEGAIAINSLVQRLPNLRLAVPAHELIWRPGMLIRGMIEMPVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXX7</accession>
    <name>A9AXX7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2303"/>
    <dbReference type="ESTHER" id="hera2-a9axx7">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04943">
        <property type="protein sequence ID" value="ABX04943"/>
        <property type="gene ID" value="Haur_2303"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2303"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_3_0_0"/>
    <dbReference type="OMA" id="WAFAEHW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2331-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="29079" checksum="0BE69B10FC43BF2C" modified="2008-01-15" version="1">MSNNRLEYWQYLPKKPLYQRPLVLLHGAWHGAWCWQNAAHDFAERGFEVHTLSLRGHGGSSMPRLFNLVGLQHYIDDLLALVDTLQPAPIVVAHSLGGYVLQHALLQRQLPAAVLLASMPQTGALGFTLRTISNQPNVALRTLLTADGFSFVRTPALAKALFLRDNASASQAQALHSQLNSESIKVLLDALMHKPEPSKIKTPIMVIAAERDRAFTLAEQRSLANAYQAPLIVVPQAAHDLMFDPAWPLVADAIEGWASRHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY17</accession>
    <name>A9AY17_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4267"/>
    <dbReference type="EnsemblBacteria" id="ABX06899">
        <property type="protein sequence ID" value="ABX06899"/>
        <property type="gene ID" value="Haur_4267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4267"/>
    <dbReference type="eggNOG" id="COG1300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069787_0_0_0"/>
    <dbReference type="OMA" id="QVWTNNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4314-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36760" checksum="33EED5662FF887F1" modified="2008-01-15" version="1">MVAEDFINAKHHAWERLTQLTSRAQSNIIAMNATELQELGRLYRQATSDLAQARRDFPGHPLTIYLNDLVAKGHSSIYRERNSPITGIKNYFLYQLPQAFRELLPFTGIAFLAFFLPAVVAWVISYQDPARGIALAPEFQPAIDNMQDDIEWWRDLNDNNAEGAVMILSNNIFVSFQAFVGGLTLGLLTLYALYYNGLMLGILAGSAQNIGFADNLWGFIAAHGPVELSIIFLAGGAGLQLAWAILRPGMVSRRAALAIAAQRAFKVSGAIVMFLILAGLIEGFISPQYLPLWFKIAVGIISAGSMYAYLLLAGRNVQQPESAEASALKLETPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY50</accession>
    <name>A9AY50_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4300"/>
    <dbReference type="EnsemblBacteria" id="ABX06932">
        <property type="protein sequence ID" value="ABX06932"/>
        <property type="gene ID" value="Haur_4300"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4300"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147394_1_0_0"/>
    <dbReference type="OMA" id="QYYVPFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4352-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="13124" checksum="7BDAF02F7D7B07DE" modified="2008-01-15" version="1">MSRETRSTAEWISLVISIGLLSCLVGLIGWLWVTEGDQPAQFRLELGQVRQVEQQFYLDLTVHNDGDRAAAAVEIVGSLDDLQSNVTLDLLPGHAEQTVTLIFNSDPQSAKIAVVGYSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE3</accession>
    <name>A9AYE3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0877"/>
    <dbReference type="EnsemblBacteria" id="ABX03525">
        <property type="protein sequence ID" value="ABX03525"/>
        <property type="gene ID" value="Haur_0877"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0877"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684782_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-891-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="45172" checksum="280802BB9E798FA6" modified="2008-01-15" version="1">MLKQQMATGSNTSDLNNLIVNQSFQDIAERFRFGAPPVSHLANFDARSDAELLKAAADHPSALERERALWEYAHRNQKAALAVLSNHLNIESDPSVRWNLLWLMVKVGEDAAVPALTAALSDPHSEVRDWATLFLEELTGQEYPMVYNEVQYENDRTFDQTLPLQIAGFADVNVPGMGWVQARLSPQWFSSILGRVLACTNSSSFMSDLVIEKELLNYHEDGSNHYETFMFRGASYPITDTVTQHIYESNTMRPFYQSGKVKVGAPIVTPVSLARAAGTERLRPGKLKEMNMHASDGVEGARGERLREVGIVRSVRGRFWGWAHTDLNRYLETGIIAPGSVQLVSTADPVVGKMANTVIYGTFRGKLGDLTGDGKLNVNLIPCHGTINGELDLNCDGIADEDPRIPRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE8</accession>
    <name>GPMI_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="1">BPG-independent PGAM</shortName>
            <shortName evidence="1">Phosphoglyceromutase</shortName>
            <shortName evidence="1">iPGM</shortName>
            <ecNumber evidence="1">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpmI</name>
        <name type="ordered locus">Haur_0882</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYE8"/>
    <dbReference type="SMR" id="A9AYE8"/>
    <dbReference type="STRING" id="316274.Haur_0882"/>
    <dbReference type="EnsemblBacteria" id="ABX03530">
        <property type="protein sequence ID" value="ABX03530"/>
        <property type="gene ID" value="Haur_0882"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0882"/>
    <dbReference type="eggNOG" id="COG0696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026099_2_0_0"/>
    <dbReference type="OMA" id="FMDGRDT"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135901" description="2,3-bisphosphoglycerate-independent phosphoglycerate mutase">
        <location>
            <begin position="1"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="263"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <sequence length="542" mass="58504" checksum="0E03B38758B1313D" modified="2008-01-15" version="1">MTTPRPVLLAIMDGWGLAPAGPGNGVSLANTPNVNHWMATCPTTQLHASGLDVGLPEGQIGNSEVGHLNIGAGLVVYQDSTRISESIKSGEFFENPAFLEAVQIVKERGTNMHLIGLIGRGGVHAYDIHLAGLLQLMAQQGVNHTYIHAFMDGRDTLPQSGLGYMRELQQTISQIGVGQVASVIGRYYAMDRDKRWERVGAAYAAMVEGVGHTASDPISAIEQAYLRDARGDEFIEATVITDSAGVALPRISTGDVVICFNFRADRVRQITRALMQSDLNTMIQEWYANQAEQGLQLPTTIWQRPEQVSNLHYVTMTQYDATFPYAIAYPPHYITEPLAKVIADAGKRQYHSAETEKYPHVTFFLNGRREEPFAGEDRVMAASPKVATYDLQPEMSAEEVAAKLLDAVNSQIYDFLVVNFANPDMVGHTGVIPAVVKACETVDRCLGQVVPAVVAQGGAAILIADHGNAEQMIDPQTGGPHTAHTTNLVPCILVADPATGLTREQISLRAGGRLADLAPTILDLLGLQKAAAMTGTSLIETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI3</accession>
    <name>A9AYI3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0917"/>
    <dbReference type="EnsemblBacteria" id="ABX03565">
        <property type="protein sequence ID" value="ABX03565"/>
        <property type="gene ID" value="Haur_0917"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0917"/>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_2_1_0"/>
    <dbReference type="OMA" id="RYCAGVY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-931-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027624">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03604">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="61"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="437" mass="48494" checksum="03C11F08AE081DE8" modified="2008-01-15" version="1">MSKTFLSIDDILTRVAPLVNPRTGILGTATELPRTPGNPAIPVYSTNIHCAELAMAESPAGTGVFLEREWAKAKSYCEALERYCNVKHAHQNFIVATRQELGIEAVDLELFPRCSDAEYRNPANPTTPPSNRQPMRWVEGYSLISGQPMYVPAIGVYVGMHPEYAGETFTTSISTGTALAASYEQAIVTGIGEAIERDALSIAWWQKLALPQVDLREFPDPAFQERLSRVEAAQIQSYFFDATTDLGVATIYAVQVAPHGRLRTMVMSATRTNPLALPSKVLDESAASRIGIEHSLSQPLPFDPADYRTFMRLSDGAAYYADAATAPAFDFLFEQTRWRTLDQLPRLDHPDPAVEAQRLIDIFRRAGLELIVVDLTLPALREVGLYTIKVVAPQLMPFSCNYNARFLATPRLYSVPERMGYPVLAEAELNHWPQPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL9</accession>
    <name>A9AYL9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2357</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2357"/>
    <dbReference type="EnsemblBacteria" id="ABX04997">
        <property type="protein sequence ID" value="ABX04997"/>
        <property type="gene ID" value="Haur_2357"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2357"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_0"/>
    <dbReference type="OMA" id="HGGQASC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2385-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="184"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="244"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="458" mass="50130" checksum="436B7B298FA28C65" modified="2008-01-15" version="1">MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMSYSTWDGLESALNQEADLAFYRRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVANQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRITWAIGVSAIFATSVALLVGTFLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQMTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADAGELSLNRRLVDPAALIERTILSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLVNNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVPYIFARFYRGDSSRQREDQASTGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN1</accession>
    <name>A9AYN1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05009">
        <property type="protein sequence ID" value="ABX05009"/>
        <property type="gene ID" value="Haur_2369"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2369"/>
    <dbReference type="HOGENOM" id="CLU_2464812_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2397-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="88" mass="10451" checksum="451EE7E0745D5206" modified="2008-01-15" version="1">MVLPAYALEFSPTNFLEQLFELLLTVGNREFYFEQFEICEYGELPSACPHELLVFQLVVRATEFPRGEWIHIFCNDRFQILGIRFELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR5</accession>
    <name>A9AYR5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrin alpha beta-propellor repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2403"/>
    <dbReference type="EnsemblBacteria" id="ABX05043">
        <property type="protein sequence ID" value="ABX05043"/>
        <property type="gene ID" value="Haur_2403"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2403"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025051_2_0_0"/>
    <dbReference type="OMA" id="ERVGITW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2431-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="659" mass="69291" checksum="4901F7F3B855B7A1" modified="2008-01-15" version="1">MAFHSDQTLPTMRVARRIIAGLLLLAVVIGLARVGRFVHAQPAQSASLHASDWQAISELLPPNQQAYLKASNTNLGDLFSSSVAIDGNTIAIGAPNESSSATGINGNQQDNSVISSGAVYIFVRTGTTWSQQAYIKASNPDFNDLFGHSVALSGNTLVVGAVNESSEATGINGNQTDNSAMNAGAVYVFVRSGTTWSQQSYLKASNAEAFDQFGWIVALDGNTLAVGANLESSNATGVNGNQADNNAVRSGAAYIFVRTGTTWSQQAYLKASNTEANDNFAMALDLSGDRLVVGAVNEDSAATGINGDQSNNDAASAGAAYVFVRSGTTWSQQAYLKASNTEANDFFGESVTIDDSTVAVGAWWEDSSATGVNGDQNNNNTTFSGAAYVYSFDGMSWSQQAYIKASNTDTENYFGHALVLRGDRLIVSAYADDSAAIGINGDQQNADAGGSGAAFVFARVGTVWSQQHYLKASNTGVEDTFGYTMATDGLSLVVGARYEDSNATGIDGNQADNSADLSGAAYVFSLAQSVAYLPLVFKRMTTLIATINPNTIPIRPITVQGETFLSSSFILPSDLPATGTYYLSASPTSVMPSLVDDAVVLSANSTQIFRHEYSTPNSAIVTVPYATLAPYAGQSITVQFNDVYGSVVQASPMYLIWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR6</accession>
    <name>A9AYR6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2404"/>
    <dbReference type="EnsemblBacteria" id="ABX05044">
        <property type="protein sequence ID" value="ABX05044"/>
        <property type="gene ID" value="Haur_2404"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2404"/>
    <dbReference type="eggNOG" id="COG1611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058336_4_2_0"/>
    <dbReference type="OMA" id="HQKPIGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2432-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="21949" checksum="3DB4D72FD9E49D86" modified="2008-01-15" version="1">MTIKRPEFNVCVFCGSRNGAQPDYSDAARELGIATAQRGLGLVYGGSSNGLMGILANSALAAGGYVEGIIPDGLFLKEVAHPRLSQRFVVRSMHERKAMMAERSNAFIALPGGLGTFEELFEILTWAQLGIHAKPIVVWNVKGYYDPLLAFIEGAVTEGFVAPEHRRFISIRSTLDEVLHDVLNFKAPTSIAKWLERDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS5</accession>
    <name>A9AYS5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2413"/>
    <dbReference type="EnsemblBacteria" id="ABX05053">
        <property type="protein sequence ID" value="ABX05053"/>
        <property type="gene ID" value="Haur_2413"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2413"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_4_0"/>
    <dbReference type="OMA" id="HHIAVDD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2441-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1015"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1569" mass="176368" checksum="21CC10B90CBA669A" modified="2008-01-15" version="1">MTDFAAKIAALPPEKQALLIRRLQQAANEPPALVAQPRTTNTLPLSFAQERQWVLYQWDPTSPLYNIVYGVRYRGKLDIAALQAGFNTIAQRHEVLRTTFLLVDTVPHQQIHAELKPGFSVVDLRDLAETERDTAIQAQIQAETQLPFDLQTGPLLRVLLLHIRDHEYIKLVSVHHSVFDGWSAGVIISELNHLLNAAYAGEPSSLPALPIQYADYAVWQRNWLQGKVLEQQLQYWKEQLAGELPILQLPTDRPYPPVESSRGAHYRVQLSADLVERLVNWSRSEGYTLNIILLTIWKTLLFRYTNQTDLLVGMPIANRHYNDLQALIGYFVNTLVIRTKAAGDLSFRSFLDQVRAANLAAQEHQDLPFEQLVEALQPDRNLAHTPIFQSLFVFQRDTVNSFQMPELSVEPLPIETGTAKFALSLEAVSLDQQIKLNFEYKTDLFDPATIERLAQHYQNLLEAVLASPDLELSRLPMLGKAELAQLLPTPTALEANLLPLHQRFEQQVQANPQAIAVRFEQSQLSYAELNSRANQLAHQLKTLDVGPDTLVGLCVEPSLDTIIGILAILKAGGAYLPIDPAHPQERIVWLLADAKVGLVVTQARCVNKLPQAGLQLIVLDAVDSALSNQPTSNLPASAQLDDLAYMIYTSGSTGTPKGALITHRNVARLFSSTEAWFNFNNHDVWSLFHSFAFDFSVWEIWGALLYGGRVVVVPFMTTRNPAGFYQLLVDEGVTVLNQTPSAFRQLIISDAEHDLPSRLALRYVIFGGEALNVGALQPWFERHGDLRPQLVNMYGITETTVHVTYRPLSMHDVENPQSSPIGTAIPDLDLYVLDDHCLPVPLGITGELYVGGAGLARGYWNRPELTNERFIKHPFAETGRLYKTGDLVRRLANNEIEYLGRRDNQVKIRGFRIELGEIQATLMSHPAITDAIVAVNTISADDQRLVAYLVTQPNQVPRFSQLRTFLKQRLPEYMVPTSFIMLERIPLTANGKIDYRALPSQQQTKQLERSQPIAAPTSVTEQSLIAIWSNLLGVTQVGIQDNFFDLGGHSLLATQVISRVREVFNVSLNLRDFFLNPTIKGLASVIEQANQKPEQTPIIAIHKADPQARLPLSYAQQRIWFLAQIDPTSSFYTVPVALEITGPLQVAALERTLSEIVQRHHGLRTLFVSHEGQTLQQVQAAQPIQLPIHDLSDLAEAAQETAINQLLEQEINQPFQLDRDQLLRGRLLKLAPTKHVLGLSIHHIAFDDWSQGILFDEMTKLYQAFANNQASPLPELALQYPDFAAWQRQWLQGEVLQNQLNYWKQQLSGKLPLLEMPLDYPRPSVQSFNGAHEMLSIEPELYRKLNQLARDNEATMFMLLMAAWAILLNRYSNQTDIVIGTPIANRNRQELEGIIGFFANTLAIRADLTGDPTLQQVVQRIRETALNGYSHQDLPFDLLVSELLPERQANRSPIFQAMLVLQNASQSSNLDLAEVQIAPRSVETNSAKFELSLVLYDNGSSIDAWIEYNTDLFKPTTIGRMVEQLQQLLTSMTTDPQQRISQVSLVSSAEKERLLGGWSQGSDDDYDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV8</accession>
    <name>A9AYV8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bPH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4366"/>
    <dbReference type="EnsemblBacteria" id="ABX06998">
        <property type="protein sequence ID" value="ABX06998"/>
        <property type="gene ID" value="Haur_4366"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4366"/>
    <dbReference type="eggNOG" id="ENOG503172B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137895_0_0_0"/>
    <dbReference type="OMA" id="SITHFAV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4419-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="14216" checksum="3AABCE5747E89B7B" modified="2008-01-15" version="1">MGLFDGLMGNASEVDPQAAQRDFAQLLAWGEQVQRAYQLIRDFFIFTDKRLILVDKQGITGSKVEYHSIPYRSITHFSIETAGHFDLDAELKIWISGNPVPIQKQFNSRINIYQLQAVLAAFVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD3</accession>
    <name>A9AZD3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AIG2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2437"/>
    <dbReference type="EnsemblBacteria" id="ABX05077">
        <property type="protein sequence ID" value="ABX05077"/>
        <property type="gene ID" value="Haur_2437"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2437"/>
    <dbReference type="eggNOG" id="COG2105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083466_2_0_0"/>
    <dbReference type="OMA" id="YERVIRM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2465-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGACT" evidence="1">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="17150" checksum="FC5125D6320AB3B9" modified="2008-01-15" version="1">MSDQPAYDTPLPLFVYGTLRTGEYNWQIYLAGKTLSETPAIAHQHQLYANRYPYMIVGEGSVVGTLVEIKPELYQAVMQEIDELEQFRPAGNSWYLRVVRDVQVGERQVLAWMYYAGERVTQHLTDDHHIAHGDWVRWNAEQANHSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE2</accession>
    <name>A9AZE2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2448"/>
    <dbReference type="EnsemblBacteria" id="ABX05086">
        <property type="protein sequence ID" value="ABX05086"/>
        <property type="gene ID" value="Haur_2448"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2448"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_5_5_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2475-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20812" checksum="9C5ACBD53CEA05C2" modified="2008-01-15" version="1">MATIREGNKAALVVVDVQVGVMNGTWEAARVIGNIAHAVERARAENIPVLWVQHTDEEMPTDSPQWQWVPELVPAAGEPRIHKHFNSSFEQTSLSEELAALEVSHIVLAGAATNWCIRATAYGVLERGYDLTLISDAHTTGSIELENGSTIEAATIVQDLNIAMQWLSYPDRTNGIASAEQINFARPGGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZG9</accession>
    <name>A9AZG9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A)</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyclic oligoadenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_2475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRISPR-associated Cas10/Csm1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2475"/>
    <dbReference type="EnsemblBacteria" id="ABX05113">
        <property type="protein sequence ID" value="ABX05113"/>
        <property type="gene ID" value="Haur_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2475"/>
    <dbReference type="eggNOG" id="COG1353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017487_0_0_0"/>
    <dbReference type="OMA" id="PSAFYYS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2503-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013408">
        <property type="entry name" value="Cas10/Csm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041062">
        <property type="entry name" value="Csm1_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18211">
        <property type="entry name" value="Csm1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02578">
        <property type="entry name" value="cas_TM1811_Csm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="10">
        <location>
            <begin position="443"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="731" mass="82093" checksum="A716A2B39891CD95" modified="2008-01-15" version="1">MSDPPVIRALKSMTNSVKAWDTTPLHSIFNQIAPSAEPNTQTSTPYFLQAQRFSLTESALFPITERPPVSADLQTQFNQAIEQCHAEPSIHVVQMLSLFHDYAWAVSYQPTAGETADPVVSLYDYARTKAALAAAGEQTMLVGGDLSGVQDFIYTIAANRAAKSLRGRSFYLQMLTDALAGWVLQQAGMPSTNLLYSGGGRFYVIVPAACYEQLAQWRRALGQFLLNVHDGELYIALGGATIADAAHNFEALFRAVNDQVTADKRRRFATLDNQELQAKLFTPRGHRGNEDDRCATCGYMGPSNQFEADEDDSKICRLCESTIKLAFSLHDAQFLCISQPQPNLSAVKGRTNAKDILAGLGLQAEICFDQQELIDHLNRNSAQSIHVQIIRPFAGDLAMLSQLRANYRQHVFSIRPIVNVTPKAPNGEVKSFDQLAKASRGIKRFGVLRMDVDDLGDIFGYSLAKASLARISSLSAAFSRFFEGWVGEICRDQNIAAAIYQPEQASNQAISPEQIYSVYSGGDDLFLVGSWDVLAHVANRIQHDLQRYTGYNQLIHVSAGLTLHTEKFPLYQAAKLAHHALDQAKDAAPRQAIRKNALDFLDQTIAWEAYPALINWHQRLWRLYQGEHGMVRSLLQVLMELYSQYNEHSQQRQKSGKKHTAYGPWIWRGKYQLARIRQRYENHQELQKLLRDIDEDLFTGFDDPHRISLRTIEQLGLAARWTQLLIREQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI1</accession>
    <name>A9AZI1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative lipoprotein signal peptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2487"/>
    <dbReference type="ESTHER" id="hera2-a9azi1">
        <property type="family name" value="UCP031982"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05125">
        <property type="protein sequence ID" value="ABX05125"/>
        <property type="gene ID" value="Haur_2487"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2487"/>
    <dbReference type="eggNOG" id="COG4188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045366_1_0_0"/>
    <dbReference type="OMA" id="GHFVFMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2515-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016986">
        <property type="entry name" value="UCP031982_abhydr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031982">
        <property type="entry name" value="UCP031982_abhydr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="35984" checksum="627C38CBBF28974E" modified="2008-01-15" version="1">MYNVGWRALSYRDNTRVDWRLGSDRPLLTHVWYPCDPAVPQMPMVIGPPDNPLFNAGDAAPDAPMLEGQFPLILLSHGTGGIAMQFGWLARVLAAHGYIVAGVNHHGNTGLETYIVEGFTRVWERPRDLSAVLDCLLDDPNFGPAIDQARIGAAGFSLGGYTVLALGGALLDLSSLVAAYTNAGRPLASIAPPEFPDADAVARQLEVFAGHDEHRQSYRDERVRAGFVLAPALGEAFKPDGLAAVAIPVMIIAGEADTNTPPAVNAQRYAMHIEDAALTLLEGLVGHYVFLAECTEAGCRLIPELCLDAPGVERKAIQQQASTLALNFFERHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL4</accession>
    <name>A9AZL4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycoside hydrolase family 2 sugar binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2520"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05158">
        <property type="protein sequence ID" value="ABX05158"/>
        <property type="gene ID" value="Haur_2520"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2520"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006501_0_1_0"/>
    <dbReference type="OMA" id="EEGWFYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2548-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032311">
        <property type="entry name" value="DUF4982"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040605">
        <property type="entry name" value="Glyco_hydro2_dom5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16355">
        <property type="entry name" value="DUF4982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18565">
        <property type="entry name" value="Glyco_hydro2_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2_N" evidence="6">
        <location>
            <begin position="57"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2" evidence="4">
        <location>
            <begin position="192"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="5">
        <location>
            <begin position="309"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4982" evidence="7">
        <location>
            <begin position="610"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro2_C5" evidence="8">
        <location>
            <begin position="674"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="925" mass="103466" checksum="0C39940E5F77C99F" modified="2008-01-15" version="1">MISNPPRERILFDQGWRFALGHAFDPAQDFQLDTSHFSFLAKAGYGDGAASAKFDDRAWRLLDLPHDWCVELPFDQRGTHSHGYKAIGRKFPANSVGWYRKTFAIPADDLGRRISLEFDGVHRDSKVWVNGFYLGNEPSGYTSFSYDISDYLNYGGQNVVVVRADATTEEGWFYEGAGIYRHVWLSKTAQVHVARYGTFVTSEIHEASATLTIQTTVINESQHPIEFSLLETISDPAANNVLQAQSANYQLAAGQSAEFSHQHTLNNPQLWDLASPHLYQLTTTVLLGEQAVDSYQTTFGIRSIRFDPDQGFFLNGRSVKLVGSNQHQDHAGVGTAIPDSLQEYRIKRLQEFNHNAIRTSHNPPTPEFLAACDRLGMLVLNENRLMGTNAEHLRHVEQLIKRDRNHPSVILWSLGNEEWAIEGTIIGARISSTMQNFARQFDHTRLFTIACSGGWDTGIGMVTDVVGYNYIFHGDIDAHHAKFPWQSGVGTEESNTYGTRGIYQTDASRGHLAPSPSGDGYADTEFGWQFYVKRPFLAGLFYWTGFDYRGEPTPFEWPAVASQFGFFDLCGFPKDIAYYTKAWWGQQPVLHIGYHWDWPNDLDRVKSFPIYSNCQEVELWLNGQSLGRRPIPENGHQQWEVAYQPGELLARGYNNGVEVLSASLRTSQAASQIQLVLDYGQLQQTGDLAVVTLQVCDDHGQIVPTANQLLDLQLTGSAKILGVGNGDPASHEPEQYHASYQLCPIQINAEQTVAELSTGLERALGAETQVWQPAFLHHNDDQQANPQAYILLRGSFELPQYSAASSIRLFSKSIAHDYSVYINGQLIISDIALEQGDQALELSHELVHPGQNEYLVTGRWIKKVNPWTFPNREPGVVQVIEPAAAWQRRAFNGLAQVIVQHTGGDQPISLSASNPELGTATLKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP4</accession>
    <name>A9AZP4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4466"/>
    <dbReference type="EnsemblBacteria" id="ABX07098">
        <property type="protein sequence ID" value="ABX07098"/>
        <property type="gene ID" value="Haur_4466"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4466"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_666941_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4521-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="1">
        <location>
            <begin position="297"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="45146" checksum="679B35E015F933BB" modified="2008-01-15" version="1">MQWSMRLRSLCIPALLTFMIAGFAAFMFSQPHASFAQDSEGSPPDCPGLGDLGAWFTAENEVVIINRSSVCTYEVGTAVYKKFDAVTDHQVLFASQTDQLPPNTQRTYRQTLNPCAGQMSAFFGPVLPSLMNQRYNERLLAANHFGGTNYCLRSCDSGQLLGWVGVSSNAILQSSARIGMKITGAPPWQVEFRLTGPMTMTHIEQIDPYLFTGNTWNLSDVPIGDYTMKATYIANPGVRCDSKTIQFKVASTPLPTPTPSPTPTPVPVYRARIVLNSLVIWDANRGDGLTNFDGFVRPGDTISYTLAIQNTGNMPLTNVQIVDPFSNATSFAGLSLPAPQIQPSPDGSGPIGWQIPVLQPNQRIDATFHVIVKESIRGTYTQIINNASFASNETGQQWSNTTEHIYNPDFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU4</accession>
    <name>A9AZU4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4516"/>
    <dbReference type="EnsemblBacteria" id="ABX07148">
        <property type="protein sequence ID" value="ABX07148"/>
        <property type="gene ID" value="Haur_4516"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4516"/>
    <dbReference type="eggNOG" id="ENOG5032RP9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126543_0_0_0"/>
    <dbReference type="OMA" id="LAYNARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4571-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021279">
        <property type="entry name" value="DUF2721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11026">
        <property type="entry name" value="DUF2721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="14539" checksum="B98F7DAF443100DE" modified="2008-01-15" version="1">MELTFTTPALLFPAISLLFLAYTNRFLSIAALMRELKSRYKLDRDPRIRGQLENLRYRIGIIRSMQICGVAAFFFCVLCMFVLFAGQELLGKGTFAISLLLLLTSLGLSLREIQVSIDALSLEIADLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B013</accession>
    <name>A9B013_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1072"/>
    <dbReference type="EnsemblBacteria" id="ABX03720">
        <property type="protein sequence ID" value="ABX03720"/>
        <property type="gene ID" value="Haur_1072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1072"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_6_1_0"/>
    <dbReference type="OMA" id="LAQWWGR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1089-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="18661" checksum="B95FD711579DF346" modified="2008-01-15" version="1">MATLVNKHSAVVTLPTDTQIQINRDFNVPKELVYRAWTTPELVKRWWSAGHGTVTIADIDLQVGGMWRWVTVTETGFEVAFHGVYQQLTPNELIVCTEVYEAMPDGEALNTITFSDRDGGSSLTLLVQHSCQEHRDGHVNSGMEAGMQSALDMLESAALELLEASTIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B094</accession>
    <name>A9B094_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2565"/>
    <dbReference type="EnsemblBacteria" id="ABX05203">
        <property type="protein sequence ID" value="ABX05203"/>
        <property type="gene ID" value="Haur_2565"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2565"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_0"/>
    <dbReference type="OMA" id="ETWYAMS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2593-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="4">
        <location>
            <begin position="17"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="38127" checksum="687429D17369A815" modified="2008-01-15" version="1">MANNTMRAVQKPSAAPGAKLITAPIPQPKRDEVLIRVRASTICGTDLHIYKWDPWAQSRFKAPMIFGHELAGDVVEVGSDVTMVKVGDFVSAETHIVCGYCYQCRTGAAHICRNVEIIGVDRPGCFAEYIAVPAVNVWRNDPNMPPALAAAQEPFGNAVHTALATNLSTRNVLVTGCGPIGLFAVGIAHAAGAKQIFATDINPKRLEMARTMGATHALDSRDDVVHHVLAATEGEGVDVLLEMSGHPSAIDQGFRSLRYGGFASLLGLPPNGLPDFDLANHVVFKGATVYGVSGRKMFETWYQTQALVAGNKVDLRPIITHHLPLEEFETAFELMLRGEAAKVALYPHGLDGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B3</accession>
    <name>A9B0B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2584"/>
    <dbReference type="EnsemblBacteria" id="ABX05222">
        <property type="protein sequence ID" value="ABX05222"/>
        <property type="gene ID" value="Haur_2584"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2584"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846683_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2612-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="33653" checksum="4C4F40A7EA1A911B" modified="2008-01-15" version="1">MAQDTIQAKYDELDQVASRFGKAADTTTAIFKSLESMANRLEGGDWQGDAQKAFSAEFRGEVQPAFNRLHTFFQQAQSTTLEIKKVFQQAEEEAAALFRGDVFGGGANGNGSGNGTAGNGNGSGSGSGSGNTGDGGTGTGGSGSGPTFKGKVKVHTYDYKTKTGETKPQLKLGVSGALLEDKGDLIKVDGPIPYTLKGKYQVGYGEAGIGLGVNGDKKFTIGPYVEGTVAKGELTNVYGDKNFGYTETLEGKALSVEGFAGLKDGSVGATIGGTLVSVQATKGLNVAGVNVGVTAEVGLKAELGFSIGKETKIKLPFVSFGFSFGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K2</accession>
    <name>A9B0K2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07220">
        <property type="protein sequence ID" value="ABX07220"/>
        <property type="gene ID" value="Haur_4589"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4589"/>
    <dbReference type="HOGENOM" id="CLU_1842365_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4644-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="14594" checksum="98401144042D765E" modified="2008-01-15" version="1">MQRFFGYVLLVVLMVGLVGCGGGVTDTTIPAPPSSSEYQNGQDPILDAAVSSFNQSAANVGSGTTTKFYISTATMDEIKNFYTTEMPKRGWKTIESPAVPNSVSVNFQADTNVAAINAIDLTMTGSTGILVITTGTNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S5</accession>
    <name>A9B0S5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03795">
        <property type="protein sequence ID" value="ABX03795"/>
        <property type="gene ID" value="Haur_1147"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1147"/>
    <dbReference type="eggNOG" id="ENOG502ZEK4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1684159_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1169-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="156" mass="17527" checksum="CC16D2F8AB27B28C" modified="2008-01-15" version="1">MTLEDPTRIDIVAGSLDPARPGLDLWIVDNGSVADDSLRYRLLIAKVLIYANYIASPMFTVQHPKIKRSDVLIRVVCLTAPTKTMRDVTGIVSWFDQTLRVPVVVEDAAKVAKRLDACQGEVRRYVRKVLELAQIETAPEPTSWRLPWRGKAKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V9</accession>
    <name>A9B0V9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1181"/>
    <dbReference type="EnsemblBacteria" id="ABX03829">
        <property type="protein sequence ID" value="ABX03829"/>
        <property type="gene ID" value="Haur_1181"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1181"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_4_0"/>
    <dbReference type="OMA" id="DNDANVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1203-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="35370" checksum="00E00740FE12B7D3" modified="2008-01-15" version="1">MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWETLKQADLPIRLLAGIGIGIPGQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIENDVRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVYRGSHGMAGEIGHARFGSSTIRCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAVAHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLPTGRVKLLDRDFAAGAWGGIALLDSQALARVAQTQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B140</accession>
    <name>A9B140_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2680</name>
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    <organism evidence="7 8">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2680"/>
    <dbReference type="EnsemblBacteria" id="ABX05318">
        <property type="protein sequence ID" value="ABX05318"/>
        <property type="gene ID" value="Haur_2680"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2680"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028469_1_0_0"/>
    <dbReference type="OMA" id="FAQIVWS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2710-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="559"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="672" mass="70575" checksum="A81B16124B0B0851" modified="2008-01-15" version="1">MTACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVLAAESITILGLQVGASWLSIGLGLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMATLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARINVPDLLPHGNLFGDAALILQGKDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGALAGLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFIAAQWTPALTLGLLVLLVVLRQQPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLLNAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYAAPFVLGAYLVGLMSTGLHGGWQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRSLTNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASDELAAASVGVAPVALKRLAYAWGGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLAGSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNWLWSAINPRGANFLSFGLMLYLTVWYRARARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B178</accession>
    <name>A9B178_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="2 7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pdhA</name>
        <name evidence="10" type="ordered locus">Haur_4634</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4634"/>
    <dbReference type="EnsemblBacteria" id="ABX07265">
        <property type="protein sequence ID" value="ABX07265"/>
        <property type="gene ID" value="Haur_4634"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4634"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_5_1_0"/>
    <dbReference type="OMA" id="LGYEMPC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="E1_dh" evidence="9">
        <location>
            <begin position="12"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36205" checksum="A4955730FAC34825" modified="2008-01-15" version="1">MEKQDLLADYRTMVLIRSFEEHCQQQYTRARIGGFLHLYVGQEAVAVGAIGALKAQDHLVTHYRDHGHALARGLEPKPLMAELFGRSTGTGKGKGGSMHFADKNKNFWGGYAIVGAHLLLAMGIAYSIKYKREVLGQADQDGVVMCFFGDGATNGGEFYEAVSMAALYKLPIVFLCENNEFAMGTPLSVHTSVTEIHKKASPFMPGERVNGNDVEEMRARALYAVNHARTEGPYFLEAMTYRLRGHSAADPQMYRTRDDINARRSGDPIALLKQKLIDQNLLTEKQAKQIDKEVEKEMDVVVQFAEESPAPDLSEAWTEIYSKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B191</accession>
    <name>A9B191_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4647"/>
    <dbReference type="EnsemblBacteria" id="ABX07278">
        <property type="protein sequence ID" value="ABX07278"/>
        <property type="gene ID" value="Haur_4647"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4647"/>
    <dbReference type="HOGENOM" id="CLU_159325_0_1_0"/>
    <dbReference type="OMA" id="MNEHAPQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4704-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10563" checksum="C91D55BE86B6906F" modified="2008-01-15" version="1">MNEHAPQRFVRDPAIVTRSIGSETVLVPVRPNTAALNAIFALNETAALVWQALATPQSLAELIDLVCAEYDVEPRAAQADLIPLLESMLEAAVIQEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A8</accession>
    <name>A9B1A8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4664"/>
    <dbReference type="EnsemblBacteria" id="ABX07295">
        <property type="protein sequence ID" value="ABX07295"/>
        <property type="gene ID" value="Haur_4664"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4664"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_0"/>
    <dbReference type="OMA" id="ESRNFYC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4721-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="127"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="194"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="44200" checksum="470F75E22AE79365" modified="2008-01-15" version="1">MRRFLHQSSLLLLTLAIALGLVSLVGHFGLMLPMSELEGIIKLFGSLGFGAGIVAIVALQSRMLSLLRSLRAQIIAAIGLGGILVAALLQGVARAMFISTDHDLPLLLLVLIFMLVLALGFSIAVGNVLVARLAEVRAGAAALAKGDLALRIPEHGNDEVSILAADFNQMADALAQSAERQHELEQSRRDLIAAISHDLRTPLTAVRAMIEALADGVVTEPAMQQRYLNSANSQLTNLSTLVDDLFEMAQLDAGVLRLELERASLGDLISDTLSNLQPHAAAHGVQLRGSVAPEADLVLMNAPKLQRVLYNLISNALRHTPSDGTIAIQAQTINQTVHVEVSDTGEGIQPDDLPHIFERTYRGEKSRSRDYGGAGLGLAIVRAIVEAHGGNVWVESQPQHGARFVFTLQTPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E3</accession>
    <name>A9B1E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4699"/>
    <dbReference type="EnsemblBacteria" id="ABX07330">
        <property type="protein sequence ID" value="ABX07330"/>
        <property type="gene ID" value="Haur_4699"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4699"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_1_0"/>
    <dbReference type="OMA" id="GDHFKRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4756-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003854">
        <property type="term" value="F:3-beta-hydroxy-delta5-steroid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3Beta_HSD" evidence="1">
        <location>
            <begin position="10"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="36968" checksum="CB881B936A2D5D26" modified="2008-01-15" version="1">MALEQSTRALVIGGCGFVGKHLVQQLLAAGHPVRVFDLQPYPDPQVESVVGDLRKAEQVLQACHDVGTVFLCAAAVDWGWGNAQLLHDVNVLGPQHVVAACQATGVAQLIYTSSVDVVFEGKPIRAGDEQLPYPKQHLDIYGATKTAGERLVLAANGQAGLATSALRLGGVYGPGDSHRLPSLVNLGKRGPIPRLGNGSARFSHIYVENAAHGHILAAQRLTADGAMGGQAYFLVDPNPDNFFLFLKPIVEALGLRMAKRHVPFGLMHFLAWPSEFWYRTTRSKTRPSLTRYTVTSTCVDFWFTGAKAANDFGYQPLVDLAEARQRTIAWAKREFNLGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F8</accession>
    <name>A9B1F8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS system, fructose subfamily, IIC subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Haur_4714</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4714"/>
    <dbReference type="EnsemblBacteria" id="ABX07345">
        <property type="protein sequence ID" value="ABX07345"/>
        <property type="gene ID" value="Haur_4714"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4714"/>
    <dbReference type="eggNOG" id="COG1299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013155_0_0_0"/>
    <dbReference type="OMA" id="CKLMAPH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4771-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006327">
        <property type="entry name" value="PTS_IIC_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01427">
        <property type="entry name" value="PTS_IIC_fructo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="13">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="14">
        <location>
            <begin position="130"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX07345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="483" mass="49720" checksum="F8807DF65CD3E3BC" modified="2008-01-15" version="1">MARIVAITSCPTGIAHTFMAAEGVQRGAEALGHQIKVETQGSVGAQNVLTEADIREADLVIIAADTKVDLGRFVGKRVYETSTKAAITDGQGMVKTAFDQAKTYNASGSANLADTVDDLKAQRSASRSGPYKHLMTGVSYMLPFVVAGGLLIALAFAIGGIYVYEDQYANTLGWSLFQIGAKSGFALMVPILAGFIAFSIADRPGLVPGMIGGMLASSNGSGFLGGIIAGFIAGYATDWLNTNIRLPKTLAGLKPVLILPLLSTAIVGLLMIYVIGKPVSAVNTSLNEWLTGLQGTNAILLGLLLGAMMAFDMGGPVNKAAYTFAVGLLASNVYAPMAAVMAAGMTPPLGLALASLLFKNRFTAEEQEAGKAAAVLGISFITEGAIPFAARDPFRVIPAIMLGSAVTGALSMSFGATLQVPHGGVFVLPIPNAVGSLGLYIVAILVGTVVTAAALYALKRPLLQTPVTTSETNASATSAVSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W8</accession>
    <name>A9B1W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2772"/>
    <dbReference type="EnsemblBacteria" id="ABX05410">
        <property type="protein sequence ID" value="ABX05410"/>
        <property type="gene ID" value="Haur_2772"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2772"/>
    <dbReference type="eggNOG" id="ENOG5030BY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2523003_0_0_0"/>
    <dbReference type="OMA" id="SHEPAVI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2803-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021377">
        <property type="entry name" value="DUF3006"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11213">
        <property type="entry name" value="DUF3006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9511" checksum="C551275EEC1CD0CB" modified="2008-01-15" version="1">MLVVFDRYEGEHAVLIDQHNHQIYNIVIGCLPASAQVGDYLDLSFDTANQPQLILAPEQRQAAEQRITAKLERLRRGDHLANNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X0</accession>
    <name>A9B1X0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2774"/>
    <dbReference type="EnsemblBacteria" id="ABX05412">
        <property type="protein sequence ID" value="ABX05412"/>
        <property type="gene ID" value="Haur_2774"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2774"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_433986_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2805-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="309"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="571" mass="62164" checksum="5A3E33EA38623EF7" modified="2008-01-15" version="1">MARHSLSPNRSLQRAWRFDRGLPKPLLLLLLLDLCLLLPVPWLLPSVFDPQPHSQPSTNLAIEVPSATAIPQGAGIGSAAEQRQLPLLIDPVRLQDARYGDAQTIARLLAKYWPSLAKQTFDVGNGIQQDAANIITGQALRWNINPLILVSLLAINYDVANSPRFEQAFGGPEMGFPQQVLWATIELREGLDQPITNTFQLQHGGWWSTEQPLDRANASLLRVLAQTRNQTELEQLLGAGNQSWVAQVTPIMGDPRQPIYNPVIDQPFMVTPFNAANHPIAQFDHQYPLINADGTMLGNGLSFELGYDGHNGWDYALPADSPILAVAAGTVLFAGWVDSGCATPAGVVVVQHLNGYRSAYWHLGRVDVQAGQQVAQSELLGLIGQTGCSVNDHLHLSIQRLGRDVNPAGWCSTLPDPWAAHPAGASSRWLWLDQVDSCNQPAMSSLADDSDPATTTRYGSGWQIDSAGNFNGSHWTSTGGQTLWRPWIAQAGRYRVMVFIPNVATKAGTAHYRIAHSDGMSEIVIEQAKHAGSWLSLGDFWFDPGQIGRIGLSAIPGTLTWADAIAVQSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P4</accession>
    <name>A9B2P4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="3">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Spermidine synthase</fullName>
            <shortName evidence="3">SPDS</shortName>
            <shortName evidence="3">SPDSY</shortName>
            <ecNumber evidence="3">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">speE</name>
        <name evidence="7" type="ordered locus">Haur_2857</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2857"/>
    <dbReference type="EnsemblBacteria" id="ABX05495">
        <property type="protein sequence ID" value="ABX05495"/>
        <property type="gene ID" value="Haur_2857"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2857"/>
    <dbReference type="eggNOG" id="COG4262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_345737_0_0_0"/>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="3">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="817" mass="91630" checksum="7FDB33D34B45517A" modified="2008-01-15" version="1">MTIVLDQRSDQSLAVYIDGDLQFDSRDEGVYHELLALPALALAQARRPKRQLRALICGGGDGFVARELLKSSAIKQIDLVDYDPTILDLAQNEWPELNQHALTNPRLKLHICDAVQFVDLAAQAADEYDLIICDFTVPRDQAGARLHSIDWYQQLAYILHPQGLIAVNAASPSQTPVAYWMMYNSIRTADLNPKPYRFALPSFTEAGYGDDWGFFIGSRRALRPREFDHLALAEPREFLHDIEQLKRAFAFPAALAEKRTTAQPTKLASDALLHSLFAPTWDEASGTDWTSLDFVHDPAPLPKPHTSPTLVPSAVQQALQADQGLDESQVFEQVVQVMPALRAEQTRSMVREFIANPLRFLNSLDLRSLVEALLRRSRELPRKLVTELRLLRRHLQRTWENPQLLLSRGLRIVSVIALVIILANLLHPDTTYAKGDTSPGSGATSSQSMVRTNSPYDVVQAPPSTVAGRGFASSTYGRGPVDEYGTYIPTTRRYRYYGSYYGGSSYRNYNRNQRPSEDPNEGGALYRLTPETDILANGEIVIILTDQAYLLLADQVMTVVDAEDGLPIVFLQRDEALIWRTHRELDRQRRGLDGSVKAKQDWIDWVSWAGFVPWRNDDQAELNNIVQTRGTLDQAIKSLGSIPANQPAIRVAPTAGGFQLFSSVWMNAEGSLAILEQPDGSKAYLNKTGWFRDAALTQPLSEPYPDEFRTKVLVPFLTKQTTEYEAIKKRIEADLTSAKSDLSLLNSDKTEYTSIQTSYGPSDIVDYGTTEIRVDEALRRTNDDIARTQQLIQILNDQLSSLPKQNDAAKKFLQSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T1</accession>
    <name>A9B2T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2894"/>
    <dbReference type="EnsemblBacteria" id="ABX05532">
        <property type="protein sequence ID" value="ABX05532"/>
        <property type="gene ID" value="Haur_2894"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2894"/>
    <dbReference type="HOGENOM" id="CLU_2342910_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2925-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="97" mass="11329" checksum="DB307EFDCB77DA20" modified="2008-01-15" version="1">MRDFWQRVQALAGQTLATTAQHRLFSILSVDANELWLELHSTHKKRWLRRNDFEVLLQSGVDLKRLTRADIAEHMPNARFNTAYVYTILAHLGIIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B339</accession>
    <name>A9B339_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proline--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_4872</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4872"/>
    <dbReference type="EnsemblBacteria" id="ABX07502">
        <property type="protein sequence ID" value="ABX07502"/>
        <property type="gene ID" value="Haur_4872"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4872"/>
    <dbReference type="eggNOG" id="COG0442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016739_0_0_0"/>
    <dbReference type="OMA" id="ASRLFWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4932-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="11">
        <location>
            <begin position="51"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="570" mass="62365" checksum="A171A75FBB5E437C" modified="2008-01-15" version="1">MRMSKLATSTTKEAPNDAELISHSLLVRAGYVKQQSAGIYSLLPLCVRSTQKISQIIREEMDAIDGQELLMPVVTSADLWRETGRYEGVTEELLRFKDRNNKDMVLNMTHEEVVTDIMRRYIKSYRQMPVMVYQIQTKYRDEARPRGGIIRLREFTMKDAYSFHATIEDLDQYYEQVLNAYKRIYQRCGLPVEVVQSDPGMMGGKIAHEFMAVTPAGEDTLILCPSCGYSANREVAVGANPASTAALEALSQGEANTKDLAGHFGVAPTRVINIKLYKTAEGVLVVTYAPAGREINHIKLQNAVGAELQNVSEAELANYGLSGFASVAPRSLKASENVRILVDSALTTERNLVGAAGKAGHYDLNLNWERDFTGEVVDLTDVLEGQPCSRCGAPLTIARAIEVGNIFKLGTKYSAAMKCVFANEKGEMQPAIMGCYGIGVQRILASLIEKFNDARGMMLPITVAPYQVHVVGTDYQSNAETKSVADQLYSDLQAQGVTVLLDDRDVNAGNKFGDADLIGNPIQVIIGSRGLKNGQAEVKIRSTGETTMVALADLLSHVLGVRQAMFASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B346</accession>
    <name>A9B346_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4879"/>
    <dbReference type="EnsemblBacteria" id="ABX07509">
        <property type="protein sequence ID" value="ABX07509"/>
        <property type="gene ID" value="Haur_4879"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4879"/>
    <dbReference type="HOGENOM" id="CLU_481271_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4939-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="566" mass="60897" checksum="9B2DDC61B02A2B62" modified="2008-01-15" version="1">MWFIRRVCFVLVFLGLVASAWLKPAPIAAQAPLTGDQTAPLLNPVSEGTQQDFEAGLNTANGAVLYQTASYPGVSFHRRNSTVGYAYYGGGCTYLTALSSGNEDNNALSTRLDIPDGAVILGVEFQYRDTDAVNNSRLYLYRFDGAGGVATVALLNSSGNGGYGSSYTATNLNTLYDAFSYSYSLVWYSGSVGINHALCGARVKYAYNPPVARPFTMPPANQPDALQGGSSGYSFTAASDFVAFEESAAYSYSSAGCMIHTGGANLAAEVDLADGTQLAGYRAYYYNTASGAAMNANLVWIDGSSTNTVLIASTTASSGFANEYFVPPSAQIIDEFSKGYLMYIRPGTSTTTRMCGIRTFYTTPVQAKQLPVYINPVSSVIADHDASGVLLTEQQPESAPIQSLDLGTVEELASPLITNEYQFVTARSFMPRDNVYLVNSAPAGCISFGSDAEVDYTFQLPPNSGLRGIRFYYRNIAGNLGNARYWAFDGRGWYNPIFTYAIPTSTNYASQLVSYTGSHYDLSNGSVAHSLNFSILSPSNTVEFCGARIWYTTGLRSLYIPVAFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A2</accession>
    <name>A9B3A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine phosphatase with GAF(S) sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1421"/>
    <dbReference type="EnsemblBacteria" id="ABX04065">
        <property type="protein sequence ID" value="ABX04065"/>
        <property type="gene ID" value="Haur_1421"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1421"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_300303_0_0_0"/>
    <dbReference type="OMA" id="ITDSFQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1443-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="254"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="423"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="589"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="766"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="995" mass="108764" checksum="96A3A434B0C3014C" modified="2008-01-15" version="1">MLASFDRGTRLSKHRMVALGWATMLFLLASASIIWQGLPIFNSATLPVAGALLLLLDGLAVRDRSNQPLSLSGIVLLAVALISTPSTTLVLAAASGLCIRLSRLARSRYEEWGRRALEAGARTLGIALVLPFISDFGLWSKLIMLIISYIVVVQGARLIFALLWDGKQITMGTWQVSAPNIFSIEILPLPLAAIGAQMAEDFPFSLVAISAAGLVGSAWMVQRASRSLGLQRRTVAELGQINAISRAIIRAELDVDSLCQLVYGETSKVVDTSNFRLGLFEGRFFELKVRVQDGHHEPPLRVELPNDRGIVSWIRRTGRSLLVEDFDSEMDRLPAQPTYQAEYPPRSGVYIPLMTGDEVLGTISIQSSEPRAFDTDDLRLLSLIADQAAVAIDKARAYSAARRRAAQLATIGEVSRQVTAILDLDRLLPSVVHRIRVSFGYSQVHLFTFDELHQQLFFRASTASDSPFWQRQGKRLPLGLGIVGHVAVTGEPMLVNDVREEPRFLPDQHGIAAELAVPMRVGQQLLGVLDVQSESYGAFDENDFFVVQTLADQIAIAIDSASVFQSQQEEAWVLNALLQSAENFAWVSEISEMLYLSVRLPALLVGCERALCLLWQRESNRWILAEGWGLTNEQRQSIGASATDEQVPWLERMRSEGESFAAELVDLEQLSSAGLVPYSSYGAVLAQPLNSRGATLGVLLLEQCGHDETWLPRQITIAAGIAGQAAAAIESALLAQIEAARQHIEQEISVAREIQMSLLPSRLPQLAGWDSGAHWNLARQVGGDFYDFWSFRSGPSAGEMGFVIADVSDKGVPAALFMALSRSLVRGAALDGSPPSQAIERANRWIMRDSQSYMFVTLFYGIINPVTGRLRYTCAGHNPPLLYRAATGQIEQLRTPGIALGVIDDAVLGEAETIIELGDVLVCYTDGVTEAVDSTMDEWGVPRLMETIHQTAHCDAATMLHTISSRLAAHTGDLPAFDDLTLVVIKRLADANQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K8</accession>
    <name>A9B3K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2942"/>
    <dbReference type="EnsemblBacteria" id="ABX05580">
        <property type="protein sequence ID" value="ABX05580"/>
        <property type="gene ID" value="Haur_2942"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2942"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_0"/>
    <dbReference type="OMA" id="NIREVRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2974-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="22493" checksum="A9582F4260D7BF4D" modified="2008-01-15" version="1">MSSENPIYPVVTGQQIYFATLRHEHVPLYVRWFSDLGMSANLGSLGFAATLEDEEAWYQQASRQNAERITFAIHIKETDQPIGNISLFEINHRRQSAALGILIGEASQRSKGYGTEAVRLMAEYGFFFLNLHNIKLWYYGYNARAGRAYERAGFREAGRVRGAIPLGNQRYDEILMDIVRDDVDLRAMSMLVPGANHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R8</accession>
    <name>A9B3R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3418"/>
    <dbReference type="EnsemblBacteria" id="ABX06054">
        <property type="protein sequence ID" value="ABX06054"/>
        <property type="gene ID" value="Haur_3418"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3418"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_304993_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3455-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="3">
        <location>
            <begin position="836"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="888"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="973" mass="109321" checksum="771BFEC722FBAEA5" modified="2008-01-15" version="1">MSFYPTYVERPRLLTLTQHAPRVVLIIGLPSSGKSTVLEALKHSINAPSALIRLEESAHDPLALLQAICQQLGLPSDHAHEQLLRLRQPSWILIDDLDRILDAWGTFLPEHAWLSELLKNPALHIAATSLHLPNLPMIQQSIIRRQLRIVGMQELAFTSAELIELAQQRQLHLTHAQAEQLIALTDGWVAPCIFALNRSGVLNQSAVEWVMQDVMASLPAPLHQMLEAWLWLAPDSTELLQALLPHYDLHRLMMSWEYAGLLAQSSLQLQRLPEVGLRQRSDPQASYLSPWFEQAGDWYLAQQQLLPFVQKMQRLQRWDVINHSLTRNLALIDRQQFFAEIVNALNAVPVQQLSSKVGWLLVRSYHLGLRNGEKALLLVNQLLGIHQQPDDQRMLRLLKADMLRAQGAIVEADGLIQPYLDDPDLSPADQARVLRTHASYLVSLGQDDNAITHFERAYGYIQHSGINRLLGLILGDYANAAARAGRYSLADRLLRQATLLWNELNSPAGLSQTMNLRAVVALHRGQIRDAARYAQEALDNALISDNRAANGALITLGDVALADRDWTSAIARYRSAREQLRNSNMVDYHILTYALALESQATRHSSIEQLQRLLIEIDTTTAQNPLDQAWLAVARSAANLTLKLDGTIPLLQRALAGLDSEGALAKGLLYLLLSEAFWQRDQFGEARQAWEALDKLIIDGRSGLPVLLSALTVHLPELVHEAYTQWNSPFAARVLHHSLPMPQAPKLIIRLMGQVRVEMHGKPVKIPKQGILLIALLLMNPSGMTADELRAKIWGFDSSNDGWRKMLQRTRKELPDCVISDGSIYRLCFPLSEIDADILVINQTPLQGSDATLDRLQIAADYASQVFLSGHEAPWIEWERKQLSKRGAEIWISIGIQCYDALRFDQAQKAFAQALRLDISNGRAVSQAMNLEINQGRRLEALAIYDRYREALFEEYGLDPSAELQALQKRALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y2</accession>
    <name>A9B3Y2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3482</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3482"/>
    <dbReference type="EnsemblBacteria" id="ABX06118">
        <property type="protein sequence ID" value="ABX06118"/>
        <property type="gene ID" value="Haur_3482"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3482"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_3_1_0"/>
    <dbReference type="OMA" id="RAPRAWN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3519-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="95"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="21821" checksum="FE0F34E3802685A3" modified="2008-01-15" version="1">MQTLLSIIEICATIAFAISGIITARRRSFDLIGVYTVAFVTTFGGGTVRDILLDRRPFYWVQQPIYPMLMLGLAIGSFFVAKADWVALTEKAIMIPDAFGLGLFTAVGVAYGLEASMPVFIAALMGVITASVGGMLRDILCNEIPLVFQRSTQLYVTCAFVGACGYLLCTYLGFDALAVLVCTGITAAMRLGAVRYDWTLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B404</accession>
    <name>A9B404_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sbp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3504"/>
    <dbReference type="EnsemblBacteria" id="ABX06140">
        <property type="protein sequence ID" value="ABX06140"/>
        <property type="gene ID" value="Haur_3504"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3504"/>
    <dbReference type="eggNOG" id="COG3856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135532_1_0_0"/>
    <dbReference type="OMA" id="TGFFFNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3541-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009709">
        <property type="entry name" value="DUF1290"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06947">
        <property type="entry name" value="DUF1290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018579">
        <property type="entry name" value="Sbp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR018579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="108" mass="11468" checksum="A35BA3CAE7D7BAC2" modified="2008-01-15" version="1">MWIPLAGLGVGVAIGLVSGLTIPSQFARYTAVAVLSALDSIVGATRATIEKRYRNRIFISGLIGNTVLAVVLAFLGERLGIDLYLAAVVAFGVRLFENASRIRQHLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B463</accession>
    <name>A9B463_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">bPH_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4966"/>
    <dbReference type="EnsemblBacteria" id="ABX07596">
        <property type="protein sequence ID" value="ABX07596"/>
        <property type="gene ID" value="Haur_4966"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4966"/>
    <dbReference type="eggNOG" id="ENOG5033I2V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_917932_0_0_0"/>
    <dbReference type="OMA" id="IRWAGNQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5029-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027783">
        <property type="entry name" value="Bacterial_PH-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10882">
        <property type="entry name" value="bPH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_5" evidence="2">
        <location>
            <begin position="77"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33441" checksum="DE10AE4907434800" modified="2008-01-15" version="1">MNRWWAKRTLRLWVALAITLLMIGATIWATMQLLADISGTASAWRIDLTTFAWFATAVSGFLISLIMLYRVGSALTLHYRVDRNALTIHWLGNTAVVPMNLITAVEPSVDVKQKPGLLTRFGYISGVGQAADEQILNFFSTQPAEQSLLLRTTGGSYVITPAQRDSFIQEVESRLNLGVVQVQSEGVVRSTRIAYDFWLNNAVRWALVVGLLLNFAVWGLIAWRYNQLPLEVPIRIDATGAVSGVEAREQLLALPLVGLLAWLINAGFGALVYRTSRAGAFALLIGSSVIQLFLAVAVWVVVRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B464</accession>
    <name>UVRB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UvrABC system protein B</fullName>
            <shortName evidence="1">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uvrB</name>
        <name type="ordered locus">Haur_4967</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B464"/>
    <dbReference type="SMR" id="A9B464"/>
    <dbReference type="STRING" id="316274.Haur_4967"/>
    <dbReference type="EnsemblBacteria" id="ABX07597">
        <property type="protein sequence ID" value="ABX07597"/>
        <property type="gene ID" value="Haur_4967"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4967"/>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_0"/>
    <dbReference type="OMA" id="EYVDRMV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0228">DNA excision</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0267">Excision nuclease</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000099553" description="UvrABC system protein B">
        <location>
            <begin position="1"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="428"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="622"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <sequence length="698" mass="79254" checksum="B46DF17DC1D0A20C" modified="2008-01-15" version="1">MPPLKVHAPYEPRGDQPQAIAQLVNGLNSGLVHQTLLGATGTGKTHTIARVIEQVQRPTLVMAHNKTLAAQLYAEFKEFFPENAVGYFVSYYDAYTPEAYVPSKDLYIEKEAQINEEIDRLRHEATQALFTRSDVIIVASVSAIYGLGSPTDYGQVALKLKTGEIRNRDKVLRTLIDLQFERNDLDFHRGTFRVRGDTLEIFPANAESAFRIEMWGDEIERMVEVDPLTGEILTQKDHIEVFPAKHFIPNADKMQAAIGDIRLELEQQLAHLEGEGKVLEAARLKQRTLYDLEIMEELGYCSGIENYSRHMDRRSEGQTPWTLLDYFPDDFLLVIDESHISVPQIRGMFNGDRSRKQTLVDFGFRLPSALDNRPLMFDEFSKHVHQAIYVSATPGVYEYQHHEQVVEQIIRPTGLLDPMVEVRRTRGQIDDLLGEIKRRVDTGSRVLVTTLTKRMAEDLTDYLKEMGVRTQYLHSDVDTIERIDILRDLRLGVFDVLVGINLLREGLDLPEVSLVAILDADKAGFLRSESSLVQIIGRAARHIDGTVLMYADTITPAMDYAISETRRRRQIQERYNQQHGIEPKGIVKAVRDLTEGMKKVAEKPAAYQTAANPDSMTKEELFKVINALEKQMKQAAKDLEFEKAALLRDQLTEMRQTLALIDNTALLESVNRKPRAKAAMVVEDTGKRKVKGRSRGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A3</accession>
    <name>A9B4A3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Appr-1-p processing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0008"/>
    <dbReference type="EnsemblBacteria" id="ABX02660">
        <property type="protein sequence ID" value="ABX02660"/>
        <property type="gene ID" value="Haur_0008"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0008"/>
    <dbReference type="eggNOG" id="COG2110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046550_6_2_0"/>
    <dbReference type="OMA" id="CANLMWT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-8-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="22644" checksum="B98B9C8BFCA5BA59" modified="2008-01-15" version="1">MQIILADVQPAMVAAWQHICGDLPNVSIQHGSILDCATDAVVSPANSFGFMDGGIDMLYSRFFGWHVQERLQTIIQQAHFGELLIGNAALVPTDHAKIPYVIAAPTMRVPMILRGTVNPYLACRAVLLLIKHGRLADGQAIADVVKTVAIPGLGTGVGRVEPAICARQIRAAIEAVNGTNSTFPSSWWEAQAQHQWLYGADPRDLQRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4L5</accession>
    <name>A9B4L5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1536"/>
    <dbReference type="EnsemblBacteria" id="ABX04180">
        <property type="protein sequence ID" value="ABX04180"/>
        <property type="gene ID" value="Haur_1536"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1536"/>
    <dbReference type="eggNOG" id="COG1269">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034656_1_0_0"/>
    <dbReference type="OMA" id="AMTQFVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1560-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
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            <end position="262"/>
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        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="427" mass="46982" checksum="509900EE3ED89886" modified="2008-01-15" version="1">MHVPSQTYNHARNVLTLLLIAQGFLLVWASLQRLIAPQLIGFPYSPNILSLTHLITLGWASLICLAALYQLLPVLLQQPLAWRGMVDWSFGAFVVGSGLFSWAFSQAAAHWLISGAVLLSLGLLGILASYGRTLWVAQQWDVTTIGISLALTTLTIQLLIGIALVINRSMLVWPSLVAYGPLGHATLGVLGWFSTLTLALSYRLLPMFTLAHGYVCRWRWVAVLSMNFAAYATGLALWYQAPQWIMLSCVSLIVLSISAWLADVQTILKHRIRRHVESPIKLFVVAGAWLLICSGWAIAASLGWLSNSGVKQFQVLFMAAMQGWIGLAIMTMLHKIIPFLIWIARANNSKQHVPSTARELFWPQLSSISIISYGLGSGLAIIAVVINNVWLLRLGSGLIAASAMALLLNCWHGLRLEQSTKQIGMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
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    <name>A9B4X8_HERA2</name>
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        <submittedName>
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        </submittedName>
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    <organism evidence="2 3">
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3063"/>
    <dbReference type="EnsemblBacteria" id="ABX05701">
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        <property type="gene ID" value="Haur_3063"/>
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    <dbReference type="HOGENOM" id="CLU_089876_13_1_0"/>
    <dbReference type="OMA" id="TTQVWQI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3095-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15027" checksum="7393EE995107EEA0" modified="2008-01-15" version="1">MTDLPDVSAMNEFQRGTLADTLGISFTEVSLDRVVATMPVERKVHQPFGLLHGGASVVLAESLASVAGWANVMHNNQLVVGVEINANHLRSIRSGVVTGVATPLHRGRRTQVWEVRISDEQDRLICVSRCTVAVVDAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B512</accession>
    <name>A9B512_HERA2</name>
    <protein>
        <submittedName>
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    <organism evidence="7 8">
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
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            <taxon>Herpetosiphonales</taxon>
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        </lineage>
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    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3513"/>
    <dbReference type="EnsemblBacteria" id="ABX06149">
        <property type="protein sequence ID" value="ABX06149"/>
        <property type="gene ID" value="Haur_3513"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3513"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055068_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3550-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
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            <end position="106"/>
        </location>
    </feature>
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    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
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            <begin position="79"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31121" checksum="5634892D1E184A09" modified="2008-01-15" version="1">MQDPYSGYQPERVEYSPSQPVMVQLPNAPVRATWVFMAINVVMFVICILQGMSVMGNTEGDAFVLIELGAKWSPLMDIGGEWWRLFTATVLHGGIVHIGFNMYALYALGPTVERFYGSLRFSVIYLIAGIGGAWASYSFGSLTGPSIGASGAIFGLIGCLIGFFLSARSVLGDFARQNLRQMVGTAAINLIIGLSFSSVIDNYAHIGGMLMGLAVGYGLAPRLVYIADWFKPRIEAKAPSALLWLSVVGAIGFILVATWFVHNQRMNDATSVALLEELYQAWLNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A2</accession>
    <name>A9B5A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3603</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3603"/>
    <dbReference type="EnsemblBacteria" id="ABX06239">
        <property type="protein sequence ID" value="ABX06239"/>
        <property type="gene ID" value="Haur_3603"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3603"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_4_0"/>
    <dbReference type="OMA" id="LVYQIMS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3642-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731898" evidence="3">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="47"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="19870" checksum="8D42EB0582131F4C" modified="2008-01-15" version="1">MIGRLASFGCIFLLLAACASQASPTAQSLPAANVSLAQNLSLAEGTVQIGEQIPELSYEQAGKKVALSDFRGKVVVLNFWQTTCVPCRTEMPDFEAIARERQDVVFIGVNKDENAEVVQRFASEIGVSYVLPLDRDGSISQAFNVNYLPTTYFIDPNGLVQKIHVGAISRSQTLKLISDFGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B3</accession>
    <name>A9B5B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0086"/>
    <dbReference type="EnsemblBacteria" id="ABX02738">
        <property type="protein sequence ID" value="ABX02738"/>
        <property type="gene ID" value="Haur_0086"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0086"/>
    <dbReference type="HOGENOM" id="CLU_1141341_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-87-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735281" evidence="2">
        <location>
            <begin position="23"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="24433" checksum="BEEEE56E08F12DAE" modified="2008-01-15" version="1">MRWIWGCLIILIVLLPATPAAACSMIEPTLDSLTQQADLVVVATVSNIDGDQAFFTIDTAIKGSVANEPLSVLNYTIGIDPSCRSELGSGNHFAEGSKWVLFLGPNQFDGSAVWQTISFGDYGALKVEQDQVRYHEHSQEQTQALADLVGTLTNYSMAGMATATILPAGQTAEPNAPKPMPTATFDVVPIANPPQTTEPPAKQPSNIAWVLVGIGVLAGVGALIGWRRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D3</accession>
    <name>A9B5D3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c oxidase subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0106"/>
    <dbReference type="EnsemblBacteria" id="ABX02758">
        <property type="protein sequence ID" value="ABX02758"/>
        <property type="gene ID" value="Haur_0106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0106"/>
    <dbReference type="eggNOG" id="COG1845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044071_1_2_0"/>
    <dbReference type="OMA" id="SIYWWGS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-107-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="8">
        <location>
            <begin position="22"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="23135" checksum="4F674BD4FD8BF948" modified="2008-01-15" version="1">MAQAVVRDIDKNDPGRGLDLRKLGMWTFLGSEVFFFGALVVTHLSMRGVVAPSSSKANYDVAAVRNLFGDNVLTSILAFILLTSSLTMVLALDGVKTNNQKRFRFWLGATIACGLVFLGGQVYEFYHIVHEGVTIKNMMFGSTFFFVTGFHGTHVAVGVVWLTSLLVSAIRHPERYNAGNYMAVELGGLYWHFVDLVWVLIFTVIYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E3</accession>
    <name>A9B5E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0116"/>
    <dbReference type="EnsemblBacteria" id="ABX02768">
        <property type="protein sequence ID" value="ABX02768"/>
        <property type="gene ID" value="Haur_0116"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0116"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066001_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-117-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="238"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="39038" checksum="2E236602F1C7095A" modified="2008-01-15" version="1">MSLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLILSISSIGSTGILWYTNSKPVQWRLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAVTADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLHLNLLISKVLVPAFIGGGIVMIALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETPVIPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLIQLARAIRLLGAECVITGIRAHVASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F1</accession>
    <name>A9B5F1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dimethylargininase</fullName>
            <ecNumber evidence="4">3.5.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DDAH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.18" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0124"/>
    <dbReference type="EnsemblBacteria" id="ABX02776">
        <property type="protein sequence ID" value="ABX02776"/>
        <property type="gene ID" value="Haur_0124"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0124"/>
    <dbReference type="eggNOG" id="COG1834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067923_1_0_0"/>
    <dbReference type="OMA" id="HRYTHAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-127-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016403">
        <property type="term" value="F:dimethylargininase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033199">
        <property type="entry name" value="DDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12737">
        <property type="entry name" value="PTHR12737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR633199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="28238" checksum="EADD7C7B4C070FF7" modified="2008-01-15" version="1">MPTAIVRPVSPAIQQCELTHLERQPIDFSRAQSQHASYCTTLAANGYQVVELSVAEDLADSVFVEDTALVLPELAIITRPGAASRRPELAAMAAVLQNYRQLAWLSEPATLDGGDVVVLGKTIWIGLSSRSNQAAVEQVQAVTKAFGYRVQGVELGQCLHLKTAVCAVDSNTVLLNPQWVEPQVFAEYQVIEVDPREEFAANVVQLHYGRLLYDQAYSATAERLRQRGYQLILVDNSELTKAEGALTCCSVLIHETEG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H2</accession>
    <name>Y145_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0102 protein Haur_0145</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Haur_0145</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0102 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5H2"/>
    <dbReference type="SMR" id="A9B5H2"/>
    <dbReference type="STRING" id="316274.Haur_0145"/>
    <dbReference type="EnsemblBacteria" id="ABX02797">
        <property type="protein sequence ID" value="ABX02797"/>
        <property type="gene ID" value="Haur_0145"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0145"/>
    <dbReference type="eggNOG" id="COG0792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115353_2_1_0"/>
    <dbReference type="OMA" id="RNWRCGR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-148-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091247" description="UPF0102 protein Haur_0145">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <sequence length="124" mass="14054" checksum="3EE252E8257D6292" modified="2008-01-15" version="1">MADDRKALGRWGEQYAAEYLQQLGYQLIASGWHCRWGEIDLIAYDQATLVIIEVRTRRGTAHGSAAESLTLKKRQRLARLLQAYLQALDAAQTPWLGDYRIDAIAITLSRGQPQLEHFQAISIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P5</accession>
    <name>A9B5P5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence protein ComEA helix-hairpin-helix repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1635"/>
    <dbReference type="EnsemblBacteria" id="ABX04278">
        <property type="protein sequence ID" value="ABX04278"/>
        <property type="gene ID" value="Haur_1635"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1635"/>
    <dbReference type="eggNOG" id="COG1555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052011_1_1_0"/>
    <dbReference type="OMA" id="MVDIKGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1659-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLBB" evidence="1">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="23798" checksum="CBA0EFA2AC72B3B1" modified="2008-01-15" version="1">MLQQIRWQWLVGLAVAAVLGWNLWQSTASAGSESEQALSLWPTTSPTAEPTLESITPTLELTPTLAVAEATPTVALLAAYISGAVAKPGVYDLPLGARIDDLVQAAGGLDSEADSQALNLAAYLQDAQHVHVPVVGETPAPTTQPTAEPQAIAVAAPTASARQPTLININTASAAELESLPKIGQAIAQRIVAYREENGPFTTIEALQEVKGIGASTFAEIEPFITIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B4</accession>
    <name>A9B6B4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3689</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3689"/>
    <dbReference type="EnsemblBacteria" id="ABX06325">
        <property type="protein sequence ID" value="ABX06325"/>
        <property type="gene ID" value="Haur_3689"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3689"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573457_0_0_0"/>
    <dbReference type="OMA" id="CRVGAEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3731-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="4">
        <location>
            <begin position="18"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="4">
        <location>
            <begin position="149"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="454" mass="50370" checksum="A9B9E5E2D99A43CF" modified="2008-01-15" version="1">MAPLALNLQVDALQSLPNLAELPTNEATILARIGVFRAFAAGDTIPIARLRSSQCYVILSGVADTVILDRDGEPISIGELGEGDFFGNSIFFSSHSLLYAVQAQTQIFALQWSIERLHEKKQHLPLFMRLLEASYLQRRAVSALSRVPLFSHVSVEERALLATQLTRQEFGRNTVIFEQGSAGQALYLIEQGQIAVEQHGVIVATLSDGDFFGEMALLSATPHNATLRCLTPTRCLHLPGAVFAAQVAQHPSLEAAVRRVIDERVHHSERVRGDQTRQHLIKVAVRYGMFRGSHVLVRQPAQCPPDCRICEQACAERFGQTRMRLNGAKIEDWDITQSCRQCRVGAECVEACPEAAIQWDDNGALRITDACTGCNECVLACPYDAVESQTIFLQNQQGPLWQLWQRMRQQSHQIQPKTVASKCDLCAGYDDRACLSQCPTGSLQLISIEELFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T5</accession>
    <name>A9B6T5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1751"/>
    <dbReference type="EnsemblBacteria" id="ABX04394">
        <property type="protein sequence ID" value="ABX04394"/>
        <property type="gene ID" value="Haur_1751"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1751"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087539_3_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1778-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="20938" checksum="38BA36446844F833" modified="2008-01-15" version="1">MQQEDIRIQRTLKALRQAFIELIIEQGYEAVTVRAIIQRANVGNKTFYRHYPDKEALLYAVVGEMLIEGQQFLIPPDSTVAAEQNTLNAFRFASQYRDVLRVLLRSPIAEQLLGPMIEFGISEGERSFAGRGLPTDLVSYHFVASMMSLMRWWFERGTQYTPDEMAEFVNKLLIRPMSEPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6W5</accession>
    <name>A9B6W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3196"/>
    <dbReference type="EnsemblBacteria" id="ABX05833">
        <property type="protein sequence ID" value="ABX05833"/>
        <property type="gene ID" value="Haur_3196"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3196"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_413800_0_0_0"/>
    <dbReference type="OMA" id="WEPDNIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3231-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="657" mass="74356" checksum="C4D7E9DC82DA1384" modified="2008-01-15" version="1">MVLWHSLDNRLCHCFSSLFGSHMQQHSRLKLGLAWLGLIGLYSLTLTQIHTFDAYSYATAVQAKPWRESFHPHHLFYGPLGEIIYWLSQGLGYQGMAFGPLQMLNVVAGASGVIIWWRLLQRLTNQPWLATSGSVLVGGAYAWWYYAVEVEVYTLASLFLIIATGLLIRLAETPQILSNWRWLGLAHSAAILFHQTNVLWLVPVLVVWLSAAWGTTAWQQRWHAFLQYAMVGLLVVGGSYAIVMFGLSGFRTWPQVQQWLFEYANTGLWGTTNANTFANLLNGWQHTIHGWLGGAVLLASLGLIAWRWRLMWRQSRMLVVLAASWLITYSLFFGWWEPDNIEFWIACLPPWALLITLSLHTLKLPQRRWWQPALSLALVGMSLSNGWQIYANGAAANDQDRQIITELAKTGRPNDFYFVPNGLQALYAEYEFERPNSLPLSVSPGDWQHGCLEISARIVDTTSAGYTVWLDQQAVEPSPILLERYGLEQSAVTACFAPFLAQAQPITLTHARYLKLDPIPQGLPDWHWQNWSLGWRENFITASTWGAGWTFIPQQDPHLLSPRINLASSQWRKLEITMASTLPNQHGQLYWMAPGEGATEDHSVSWDVIGDGALHTYTLDLSQIPTWQGSIGMLRLDPVVAGAEQQTVTIQRLRLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6W8</accession>
    <name>A9B6W8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MPAB_Lcp_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3199"/>
    <dbReference type="EnsemblBacteria" id="ABX05836">
        <property type="protein sequence ID" value="ABX05836"/>
        <property type="gene ID" value="Haur_3199"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3199"/>
    <dbReference type="eggNOG" id="ENOG502ZETH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049598_1_0_0"/>
    <dbReference type="OMA" id="STIYVRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3234-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="PTHR37539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPAB_Lcp_cat" evidence="1">
        <location>
            <begin position="85"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="40586" checksum="98805016D52B35C1" modified="2008-01-15" version="1">MRYTQPYLESLRQIGDPAADSLIEQLANNGDLARVSQVLRQITKNDQPLPRDLPPVLFDWLEHHCSPSGSIDWQRINNGAAFFARYGMAITVVLSTAALVGCYAAQKGVKVLTQTQRLQAEPYRRVTESGHFVMTVLQPQALQNNGAGLQVIQKVRLMHAAVRYQIAHAGQWQSAELGVPICQEDMLGTLMVFSYGVIWGLEQLGYRIAAQAAENFLYTWCVIGELIGVDPASLPRSMAEAEDLAYSISNRQHGPSDEGRELTQALLAMHTGLLPGRFFDGMVPALIHHLAGDEVARWMGVPQTRWKYAVRYLKTLNSAMRSITQRFPAIDEQFDRLTFLLLQRWTGAIHRGELSETLSERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X2</accession>
    <name>A9B6X2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ordered locus">Haur_3203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3203"/>
    <dbReference type="EnsemblBacteria" id="ABX05840">
        <property type="protein sequence ID" value="ABX05840"/>
        <property type="gene ID" value="Haur_3203"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3203"/>
    <dbReference type="eggNOG" id="COG2127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134358_3_0_0"/>
    <dbReference type="OMA" id="TEDQAYK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="13014" checksum="CF42C0A7183C1E29" modified="2008-01-15" version="1">MNTRRDVATAEPQTTTDVELDFITLSDEELEKPYRVILQNDDITPMEVVVWVLEKVFEQSFEQAKRIMIEAHVKGHALVTILPFKEASARVYSAQSRARDMGFPLVLFLEPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B708</accession>
    <name>A9B708_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein Haur_3239</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3239"/>
    <dbReference type="EnsemblBacteria" id="ABX05876">
        <property type="protein sequence ID" value="ABX05876"/>
        <property type="gene ID" value="Haur_3239"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3239"/>
    <dbReference type="eggNOG" id="COG2835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2094394_0_0_0"/>
    <dbReference type="OMA" id="YREDSVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3274-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13131" checksum="F71A0EE501122225" modified="2008-01-15" version="1">MKFGKLLRFGIIAGAGALVYRVYKQYKADQAFELAPVSNLGSNTTAVSASSTKRSISPELLEILACPVDKKPVELYTDASGKEWLLNPRNGYRYPIEDGIPIMLIDEGEKHKDTSLIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B710</accession>
    <name>A9B710_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3241"/>
    <dbReference type="EnsemblBacteria" id="ABX05878">
        <property type="protein sequence ID" value="ABX05878"/>
        <property type="gene ID" value="Haur_3241"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3241"/>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_356341_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3276-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="36"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="718"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="789" mass="89145" checksum="C09D5B4E5452CC4B" modified="2008-01-15" version="1">MGDRTRSLARIKWHATTKMTAQEHIGIPMNKPKQDVAVFIDFENIYVSVREKFDATPNFEALMERCEDYGRVVVARAYADWYRYPRITSALFANNIEPMYVPTYYYDKDEGRMGRPIKNSVDMHMCIDAMRTLYTRTNIGSYIFITGDRDFIALVNCVRQEGKDVIIVGIGGAASSHLAQSADEFLFYEQIVDIRPMGGRRNERHEKTFERVERPERVERNDRSERPERPERSERPERSERSERNGRDDRRRERERPEKNAEPTFERLDSRSEKTAEPRVEKPAEKAPEIVVRPAPSTAPVVATTPSNPDAAIYDKLVEALHLARKRGYVTSFGSLKVLMKELLPNFKESRYRDAQGKPFTKFTDFVREAERLGKIQIFTSGTVNEVFLPDEDPYKLSQFAEDLPSVEAERELEQELELQAESIAPITIETIGIADEPMELADGEEVAPSSERGDRNGRRRRRRGSSRSEQPAVDVLPEELSETILVPAPTEGFSFGEREWQLFYQVMGVYSEPVPFADIFNDLREMRNTAELDLTNNALKELIKQAINEGKVQRSNRGAKAHYRLVLNPEQFDGAITTFEPSDLEAFDDGPSLPDLVDEEPRLLPAMIGGQTIAIDDDYTAPIDEVALPESFEEQPLPESDADYSFAEPIEYEAPVATSTAAIKPRKPSRRRKSIVPLSVAEAIAASVANDPAPEPAVEVEAVAEPVAEIVSEPIAEPVVEAVTEEKPKKRGGRRKAAEPVEVVEEKPKKTTRRKKAEPVAEAPAPVEPAKKQPRRRKKAASETGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B739</accession>
    <name>A9B739_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3270"/>
    <dbReference type="EnsemblBacteria" id="ABX05907">
        <property type="protein sequence ID" value="ABX05907"/>
        <property type="gene ID" value="Haur_3270"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3270"/>
    <dbReference type="eggNOG" id="COG4270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128738_4_0_0"/>
    <dbReference type="OMA" id="WWYHGPR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3305-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13682" checksum="CACF932F7F4EED34" modified="2008-01-15" version="1">MKRLVRGLLASFMVLVGVLHFTNPKPFIKIVPPSLPRPRSMVYLSGLFEILGGLGLLLPGVRRKAGLGLMALYLAVFPANIQMLKQNPPLFGKQRPVLLWLRLPFQPLLIWLAWWVSRDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B740</accession>
    <name>A9B740_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Deoxyribose-phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3271"/>
    <dbReference type="EnsemblBacteria" id="ABX05908">
        <property type="protein sequence ID" value="ABX05908"/>
        <property type="gene ID" value="Haur_3271"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3271"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_3_0_0"/>
    <dbReference type="OMA" id="RYSGPDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3306-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="35963" checksum="0EBB0B2E36AAC724" modified="2008-01-15" version="1">MQTEVERVTAMTHEQRNPISPLDLGWVNSIRVNRSAVERRVSSLPNRRTVKKDWQAAWLLKAISCMDLTTLSGDDTVGTVQRLCLKARQPIRGDLVDALGIRSLNLTVGAVCVYHTFVATAVQSLQGTAIPVAAVSTGFPAGLSPMELRLREIEASVAAGAREIDIVISRHLVLNGDWQGLYDEVRAFREACGEAHMKTILATGELGTLRNIAQASLVCMLAGADFIKTSTGKEPVNATLPVSLVMVRAIRDYHEQTGYKVGFKPAGGIRTAKQSLDWLALIKEELGDQWLHPHLFRYGASALLGDIERQLEHYLTGQYSSAIRHPMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B749</accession>
    <name>A9B749_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3696"/>
    <dbReference type="EnsemblBacteria" id="ABX06332">
        <property type="protein sequence ID" value="ABX06332"/>
        <property type="gene ID" value="Haur_3696"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3696"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_0_2_0"/>
    <dbReference type="OMA" id="AGIHFCI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3738-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="380" mass="42778" checksum="61623A923DDB183C" modified="2008-01-15" version="1">MQSLLNPYPWFKTMREQNPVYFDQTIGSWVVFRYADVKQVMTDYEHFSSAPPDRGDGMNMFANSMLMTDPPRHRQLRSLVNLAFTPRMIEQLHDRIDGLVNRLLDDMLAQPEPDFIRDFATPLPMTVIAEMLGVPTADQDKFKYWTEQIITSSNNPDMSKIVPIYQEFGAYLFGMIEQRRNAPQADLISDLLNAQIDGESLSDMDLIGFCALLLVAGNETTTNLLGNAVRVFSEQPAIYAELRANPSLIPNVLDETLRYYSPVKAMPRHAHTEQQIGDVTILAGQRVMAVIGSANRDESQFPDAETFDLHRKGNQHIAFGHGIHYCLGAPLARLEGKLALEAMLKRIETITIKPDAQLEPIPTPITFGVKNLPVLITTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B783</accession>
    <name>A9B783_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3730"/>
    <dbReference type="EnsemblBacteria" id="ABX06366">
        <property type="protein sequence ID" value="ABX06366"/>
        <property type="gene ID" value="Haur_3730"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3730"/>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082566_1_0_0"/>
    <dbReference type="OMA" id="CWKLNDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3772-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="29"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="24082" checksum="1D0D3E44A6286F84" modified="2008-01-15" version="1">MITIETLAIGQPQTYHDAKGAWSSAIGRQAITTPVRLEQLGHVGDAVADTKNHGGPDKAVCCQPASHYPLWQAEYGLANDHPMLQASGIGENWTLSNVTEQDVCIGDQFKVGSAIVQICAPRYPCTKQDRKLGLDGLQQRTIATLRSGFYLRVLQAGEVQVGDGLELIERPHPTITVHKVNQHLHHERDQAFGRQLLVVDELAASWKRIIQMIIPSLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B785</accession>
    <name>A9B785_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <sequence length="343" mass="39876" checksum="EE50CD6D0839002E" modified="2008-01-15" version="1">MQTRIRWHTVLSIGMLLAVLASAAGYFYWASRPFTLEQLAPVDKPTLVHTIKLPEAGSEFAWNSRGDRLAVAHLDLNKEDQSVVSIYTVDGKRLRQLAVNIDAFNTIDDLEWHPTKDILAVSYRQALVLWSADGTIIKRINNGIESAFQQLSWNQQTNELAVIDYYAYNGEYYNQIVLFDEYGTKIRRFPTKFGYTTQMKWINQVNIIVNVTNRIYTFNTITEEWIRLFEDEQYAVDIDSNHNRIVGAGENNDKELEIWQNGIIKTIELAEFSGRIPKSSPRGDYTVLYTIGRLNFFNHHTQEFEIHPLTNKDLIYVTVEWHPSKPILATLLFYEIQVWQFPE</sequence>
</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02944">
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        <property type="gene ID" value="Haur_0292"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0292"/>
    <dbReference type="HOGENOM" id="CLU_1822674_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-295-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="14972" checksum="DDCD6D810C3AF3E7" modified="2008-01-15" version="1">MANRRISTIVMAVLGVLMLVGLFLPYLKSTTTDFSISVFQTFGSDLKGLVPEDSKTLYMIIAAAVAVGGLFALLSLTGKKVFGVFSIIVSFLIAAFHGLLTAGLSGERDVVQGLGFWLLLGVSLALFITSIVFVARKPKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B858</accession>
    <name>A9B858_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3355"/>
    <dbReference type="EnsemblBacteria" id="ABX05991">
        <property type="protein sequence ID" value="ABX05991"/>
        <property type="gene ID" value="Haur_3355"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3355"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_648554_0_0_0"/>
    <dbReference type="OMA" id="WINTISE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3392-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        <location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX05991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="46794" checksum="BEB5833B743FF199" modified="2008-01-15" version="1">MIKESTPTQASVAEAPAPAKLPRARLFQISFGVGGVMLARVLGIFTQIILARRLGAEQYGLFNSLYALLNPLIILANLGLDNWLLRQSTDRTKLNKSVSRVFALRGFVLAGLLLAAAPFVSMRSPEFTPHLIALACAGIIGDLLVGTADTALRASIQVLKASSLQIVVALSLFVPIWFTPNLPFSTVVIYRCIAVALGFGLSVYYLHGILRWVWQPRQWINTISEARFYFISEVMAYLTLRVDLFLVALLLPTINSGIYAPPLAIINNTFLVPSITAQILLPMIVKHPPRSPLYRRVISLAIGLSILYGLAWLALLTWHSDWIINLMYGPQYADAIPLLQIMAIIPLLKSLNFCWATFMVSNDQQPLRVKLQTIGATISILGNFVVIPLYGLHGVAIINMITEIALFISYGYGAWLTYKKVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B861</accession>
    <name>A9B861_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="1 2">
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3358"/>
    <dbReference type="EnsemblBacteria" id="ABX05994">
        <property type="protein sequence ID" value="ABX05994"/>
        <property type="gene ID" value="Haur_3358"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3358"/>
    <dbReference type="eggNOG" id="ENOG5031FR6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1793029_0_0_0"/>
    <dbReference type="OMA" id="FENIPPH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3395-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="18125" checksum="946682CBEA0BE3BE" modified="2008-01-15" version="1">MRKILLMGLMIGALVGCSDSSTTPTAGPLPTVGALPTPTMRGDIVQDIDLTQIKDPESGKATVFGNVSNPTNNQPYSQVQVQLAEAYDNDKGETNFVLNTVQSPITFADDQGDFVFENIPPHRYVVVVGDVYSNYKILLGPDQVTMVIDAKVDQKLDLGPLKVDIFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H1</accession>
    <name>A9B8H1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="13" type="ordered locus">Haur_5005</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="13 14">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="14">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="13 14">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07635">
        <property type="protein sequence ID" value="ABX07635"/>
        <property type="gene ID" value="Haur_5005"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5005"/>
    <dbReference type="HOGENOM" id="CLU_008142_4_2_0"/>
    <dbReference type="OMA" id="AADQFEI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0614">Plasmid</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX07635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="647" mass="70680" checksum="E6175EF6640ADAE3" modified="2008-01-15" version="1">MAQTVNDHIPSGDSDADGHHTQHTAIPRGRYLALLSLSALGIVYGDIGTSPLYAMRESFHAGHGLALTPANILGVVSLIFWALVIVVTIKYLIFIVRADNQGEGGILALTALATPIKQVGTTERKWIVLLGVFGAALLYGDGIITPAISVLSSVEGLNVATPFFQPYIIPLTIVILVGLFLIQRFGTALVGKLFGPITLLWFTVLALLGIVNLLHEPSVIRAINPLYGLAFFQANGWKGFLVLGSVFLVVTGGEALYADMGHFGRRPIRVAWYVVVLPALLLNYMGQAALLIREPEAVENSFFRMAPTWALYPLVILATLATVIASQALISGAFSITMQASQLGFLPRTRTFHTSRTEYGQIYIPAVNWLLMVACILVVIAFQTSSNLAAAYGIAVTSTMAITSIIFYVVARDRWGWSGLKAGLLIGFFLVIDMAFLIANAIKIPHGGWFPLVVAVVLFTIMTTWKRGQRLVAERASSDHLLSELTDRIQHNPPVRVPGTAIFLSARRDGAPEALLANIRHNGVLHEHILLVTVVYRQVPHVHAQERFLVGEEGHGFRTLTIYFGFMEDPNVPMALAEATIPDLPFDPEHTTYFVNRTKVIATKELPGMALWRERLYAVMLQNSTSAADFFSLPPTATIEIGTRVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z6</accession>
    <name>A9B8Z6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07810">
        <property type="protein sequence ID" value="ABX07810"/>
        <property type="gene ID" value="Haur_5183"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5183"/>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5245-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="804" mass="90062" checksum="3E143F17762C405D" modified="2008-01-15" version="1">METFGRWLKHQRISHDLTQEALAERIGCSVSLLKKLETHQRRPSKQIITRLATIFKVDAAVVIKWRTTDPTPEVNPVGAYLPIPLTPLVGRATDVAALQILLRQDTVRFLTLTGPGGVGKTRLSLALGAACQLWFPDGVWYVPLAPVHDADGVLPAIMHVLRLPTPPDQTVLETIQNMLRHRHALLILDNFEHVLAAAPMIATLLESTTQLKIVTTSRALLHIPGEHCMVVHPLSLVVEPTGKGVHAAHSAAMELFLQRAIAVNPQIVITDEALAAIRTICVELEGLPLAIELAAARCQIVTPQELRTVFRSRLMLAKSTNYTRPQRHSSVWDALLWSYQLLDPMAQSIFRTLGACVDGVLLPTLQAMFANEDEAAPSLMDYLHLLANHSLISLEPTTTGVLALTMLETLREFAHLLLVRHGEELYARRRHADHYRAFLVDINIRLEKADSVSWVAQFDHEAANIDHALHWLMTHDPAVAAEFASHLAPVWMNRGSIQYGTIWLERCITLPRLDPLLEAMLARDLGAFWITAGRYADAEAVLIPALAMFKSARRERDQVRIYFMLAYAAIQQNRFVIAEQYLARCEDWAHSNAEIERLTIIFHNQAQMFEQQGNYETARIKVQAMLNLCQILKYPANSALAWTRQGFIDLAQGSVDAAEHALFQARRMLEQTISFDRGDLVDMRRLDGLLALAHGDHRRARVILGQTLAMAAELNDIPRVVQTLDACLWYTYRTKDLHISAALLGLQQRLRRHYAMPAPPPVQSQLDSLATSLTNGLEPDVLGHWMQHGATWVIADACRQLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A1</accession>
    <name>A9B9A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07915">
        <property type="protein sequence ID" value="ABX07915"/>
        <property type="gene ID" value="Haur_5288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5288"/>
    <dbReference type="HOGENOM" id="CLU_2058139_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5350-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13496" checksum="7AC4ED8027448254" modified="2008-01-15" version="1">MPPDHLAFNRSGQRPQLIALGLIEFAIACKLTAHSIHLALPPPIIQLRVVDAQGDFGTLSQFLWLPRDALQNHPPHIHGQVFHQQCLQRGDQLPAICLGLHRIVHKIYLSIFYSNYCYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU98</accession>
    <name>A9AU98_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asp23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0366"/>
    <dbReference type="EnsemblBacteria" id="ABX03017">
        <property type="protein sequence ID" value="ABX03017"/>
        <property type="gene ID" value="Haur_0366"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0366"/>
    <dbReference type="eggNOG" id="COG1302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113198_2_0_0"/>
    <dbReference type="OMA" id="CYGLVGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-369-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005531">
        <property type="entry name" value="Asp23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34297">
        <property type="entry name" value="PTHR34297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03780">
        <property type="entry name" value="Asp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17368" checksum="201E0B788D2C1DA9" modified="2008-01-15" version="1">MNEKTSLANVRQNDAGRIEVHSRAIATVVAGAVVRCYGVVGMAPRNLRDSVAHVLRPEDQYKGIDVQVSTEAITVDLFVIIEYGTRIATVARNIMESVQYAVVHALGEANITVNVHVQGLRIEQADKEPKDATEGQPSRWRRFGVMGGLRGQRTEESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUA9</accession>
    <name>A9AUA9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="12" type="ordered locus">Haur_0377</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0377"/>
    <dbReference type="EnsemblBacteria" id="ABX03028">
        <property type="protein sequence ID" value="ABX03028"/>
        <property type="gene ID" value="Haur_0377"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0377"/>
    <dbReference type="eggNOG" id="COG0035">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067096_2_2_0"/>
    <dbReference type="OMA" id="TYATRMP"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="129"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="197"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="22455" checksum="A6E84BC58B9BEFCA" modified="2008-01-15" version="1">MGLHVSSHPLVLHKLALLRRVESEPKKFRELVREISQFLVYEATADMPLAPYTIQTPLSTMQGHAIGARIGLIPILRAGLGMVEPVIDLLPTAHVWHLGLYRDHNTLEPVTYYNKLPAQPDIDVCLILDPMLATGGSAVAAVDILKAWGAAKIKFLGLIAAPEGVERLQTAHPDVEIHLAALDERLNEQGYIVPGLGDAGDRQFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD7</accession>
    <name>A9AUD7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0405"/>
    <dbReference type="EnsemblBacteria" id="ABX03056">
        <property type="protein sequence ID" value="ABX03056"/>
        <property type="gene ID" value="Haur_0405"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0405"/>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_1_3_0"/>
    <dbReference type="OMA" id="GYPRVKG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-408-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="170"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33590" checksum="90EEF22F00640B02" modified="2008-01-15" version="1">MSDYVNSEVLVSTDWVAEHLNDPNVRLVESDEDILLYEMGHIANAVKINWQDDLNDVRIRDYIDGDDFAALLSRFGISNDTTIVFYGDKNNWWACYAYWVFQLLGHEKLKIMNGGRKKWIDEGRELTRVVPSFEPTNYVVGQPKPEIRAFRDDVLAHIGRPNPRQTAIELPAGHSLVDVRSPDEYTGKKLHMPEYPQEGAVRGGHIPGAVNVPWAKAVNDDGTFKSADEIRQLYGEVGVTPESDTVVYCRIGERSSLTWFVLHELLGYKNVRNYDGSWTEWGNVVGLPIHNPTTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE1</accession>
    <name>A9AUE1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 6">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0409"/>
    <dbReference type="EnsemblBacteria" id="ABX03060">
        <property type="protein sequence ID" value="ABX03060"/>
        <property type="gene ID" value="Haur_0409"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0409"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_0"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-412-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="30"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="45089" checksum="5F7D22CE779A8DCC" modified="2008-01-15" version="1">MSVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHRGVYQISEAATEAYEGTRRTIGRFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRILLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSHLDQLLTERTKLVAMTHMSNVLGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVLWARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNELGMQAIHERERQLTHYAWDKLSAIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQGIAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLAEALVLARDTFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW4</accession>
    <name>A9AUW4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3918"/>
    <dbReference type="EnsemblBacteria" id="ABX06552">
        <property type="protein sequence ID" value="ABX06552"/>
        <property type="gene ID" value="Haur_3918"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3918"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_3_2_0"/>
    <dbReference type="OMA" id="MHPERNW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3960-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="27267" checksum="9478E8704D64F953" modified="2008-01-15" version="1">MSEQTFTPKRILVVVAHPDDAEFVCSGTLSRWYREGHQIHFCLCTDGNHGSSDPNMTPERLAEIRQAEQRAAAAYVGADVTFLSFEDAALEPTLELRKAITRVIRRYKPDIVVCQDPSFRYSDDYLNHPDHVAAGNATFGAIMPAASTRLIFPDLLAEGLEPHNVRQVYLMGGERVDTWIGLTEEDFQLKLKALREHKCQLGDWEPEQMMRDWAVATAKSAREAGVECELAESFKLVTLVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV10</accession>
    <name>A9AV10_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3966</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3966"/>
    <dbReference type="EnsemblBacteria" id="ABX06598">
        <property type="protein sequence ID" value="ABX06598"/>
        <property type="gene ID" value="Haur_3966"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3966"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_29_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4008-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1447"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2995"/>
            <end position="3071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2967"/>
            <end position="2991"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1482"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3108" mass="331974" checksum="3D01195C63F06FB3" modified="2008-01-15" version="1">MTDRAAYDDAYDTAIAIVSMAGRFPGASNVDAFWQNLVAGVRSILPIADEDMLAMGMDPAVLRDPQYVKAGAFVDDVDLFDASFFGYTPREAEIIDPQYRLFLECAWEGLERAGYDLETYRGAIGMFAGSGHPTYALENIASNPSIREWAGDLQVNINNEKDSLATIVSYKLNLRGPSVAVQTFCSTSLVAVHMACQSLLTYECNIALGGGSALNLQQGLGYFYQEGGILSPDGRCRTFDAQAQGSVMGSGVGVVVLKRFEDALNDGDTIYAIIRGSAINNDGIRKVGYTAPGLGGQSSVISTAHQRAGVAPESIGYIEAHGTATPLGDSIELAALIKAFERKTTRQQFCALGSVKPNVGHLDRASGVTGLIKTTMALYHRQLPPNLDFERTSPDIDLASSPFYVNTQLREWAAEAGSVRRAGVNSFGLGGTNVHVVLEEAPAPAPVAPARPAQLLVLSAKTATALEAMTDNLAAYLAGAPADLADVAFTLQIGRTGFNHRRIVAGTSAADVRAALEQRDGRRVLSATQTGRNRPVAFVFPGVGDHYADMAKTLYATEAVFREAVDQCAELLAPRLGQDLRAALYPADQPAAAAAHTLFAATAASSRVAGALHQTALAQPAVFVVEYALVQLLANWGIRPQALLGYSLGEYVAATVAGVLSLEDALTLVAMRAQWIQAQPHGAMLAVSLGAEAIQPYLNTEVALAVVNSPMTCVLAGPQAALEAVKIRLEEDEVASRWLETSHAFHSPMLAPVAAELTALVRTLQLQTPKIPYISNVTGTWITDAQATDPSYWARHMVETVQFADGVGTLLADAQLALLEVGPGQALGSFIRQHPTCGRDRFGQIVATLPVAAEATNDLVALLNGLGRLWLAGVPVDWAGFHGGAARQRVPLPTYPFERKRFWIDVQRPEKAAALAETTAGRKPDIADWFYQPAWVRAELLGAPVKPGCWLVFADQHGLGNAVGQRLILAGHRVVQIEAGSDFVQFDEQHFQIRPGQIDDYQNLLKTAIGAGYLPTHVLHLWSLAPAAGRATGSGRFAAIQEYGFTSLLNLAFALGSQLIDDPVELLVATASIQAVDPSDLPDADNATILGACTVIGQENLSITVRNIDLSLPADLNSAELPVAALVAECQKQNSDLHVAYRGNQRFVQQYQPLRLEVPESPAVRPGGVYVITGGLGGVGLVLAEHLARTAQAKLVLVGRQGLPERAAWDAWLREHGADDATSQRIQRVRMIEAAGGSVLVVAADVAMVAGFQRVIAATEQQFGSINGVLHAAGISDSTAYNLIQLLEQATYAAHFQPKVYGLYALEAALGDRPLDFCVLFSSISAVLGGLGFAGYAAANCFIDAFTERHNRTHAVPWVSVNWDTWQLKVGQHDVIGATVAQYEMSPAEGAAAFERVAAARGHTQIVNSTGDLDARIRQWVRLESVRADAAAAADTAVQTVPRGTPLSSSEYEQRVAMVWQQILGIDEVGIDDNFFDLGGNSLVALQLVTRLKKELKTQIPMVALFEAPTVRAMSQLLRPETAPDVDQQALLLQQRREQTRQTVQADGLAIIGMVGRFPGASSVEELWQNLHNGVESTTHFTDEELVASGVNPLEIRHPDYVKSRPILKDDVSLFDAAFFGYTPREAEFLDPQQRLFHECAWEALEQAGYDTQRYPGLVGVFGGTNMNAYLNRIARDPRSDGHITEIITLENDKDALATNVAYKLNLRGPSFAVQTFCSTSLVATHLACRSLRHGECDIALAGGVSVRVPVNTGYLYEEGDQVSPDGHCRTFDANAGGATFGDGVAIVVLKRLADALADGDTIHAVIRGSAINNDGGLKVGYTAPSVVGQAAVVQAALADANLAADAISYVEAHGTATKLGDPIEVAALTKAYRTTTDKVGFCAISSVKPNVGHLDRAAGATGLIKTVMALKHNVIPATLHFQTPNPEIDFASSPFFVPTALTPWTRNGTPRRAGVNSLGVGGTNAHVIVEEAPQVGPSGPGRAVELLVLSAKTATALEAATTNLAAHLEEQPTVNLADVAHTLQVGRRVFEHRRVVVARDATSAAALLRSGDARRVLTLAQKPTSRGVAFVFPGVGDHYVGMAEGLYATEGVFRATVDRCCALLTPLLGSPIRKEIYPDGGVPAQTGVDLRAMLREDATPGSAGRLHQTAWAQPAVFVVEYALAQLLASWGIRPQALLGYSVGEYVAATVAGVLSLEDALTLVAKRAQWIQAQPAGSMLAVSLSAEAIGTYVGGAVALAVVNSPMTCVLAGPQSALEAVKTRLDGDEVASRWLETSHAFHSPMLAPVQAELTALAGTLRLQAPRIPYVSNITGTWITDAEATDPGYWARHMVETVQFADGVGTLLADAQLVVLEVGPGQALGSFIRQHPACGRDRFGQIVATVRGMTDTSDDLEVLLSALGRLWLHDVVVDWAGFRGSEVRQRIPLPTYPFERQRFWIEPDLTPRPGSGPKLRRFDAGDWYAVPSWKRAVAHNIVNNGSLTEPGCWLVLVDGEGLATRLTAWLEDRGQTVIAVTPGAAFTQHSATAYTVRPASREDFTALLQTLERQGQTPSRVVHAWLATAGDPAADETAAGFDHTLQHGFYSLLALAQALGDQGVEWCEINAVTVAMQEVTGQEDLRIAAATVIGPCKIIPVEYPNLTARSIDILLPASPAERATLVAQLGAELATPPTGDQVAFRGAHRWVQMMEPVALPAVPASHPRLRTGGVYLLTGGLGGIALGLARDLAATLRAKLVLVNRSGLPDRATWPALLERDGAEQGMGRRIQQVLDLEALGAEVLVIQADVTDAVAMARAVAEAQARFGTIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPLDFLVLFSSVTSATGGGPGQVAYCAANAFLDAYARKHATDHGQTVAVSWGEWLWDAWSEGLQGFAPEVQAEFRAYRKNFGITFAEGAEALRRILACQIPHLFVTTEDLLNMFEGSKRSAARTQAEPTEQQARTRYPRPEVGSFVEPQGELEQSIARVWADVLAIEAIGANDNFFDLGGNSLLGIGLINQLRRNLKLEKLPAHVLYEAPTVATLADYINQSTHPTGSSAVHLPDLDEEADKREEQFDFFKDRAQMEELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV44</accession>
    <name>A9AV44_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0471"/>
    <dbReference type="EnsemblBacteria" id="ABX03122">
        <property type="protein sequence ID" value="ABX03122"/>
        <property type="gene ID" value="Haur_0471"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0471"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_0"/>
    <dbReference type="OMA" id="FIDYLAH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-477-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="22504" checksum="47037A54B649BE09" modified="2008-01-15" version="1">MLDLASALAQFPILETERLVLRQPVQADRDAVFAIMADPQVLRYFGQLPMESPEQAERRLHNISQSFEQKIGVRWAITLRETGEWLGSGGFWRFMNEHARAEIGYELAAAWWGKGIMVEALQAMLQFGFTTLKLHSIEAQIHPLNHGSRRVLEKLGFHQEGLLRENYFDLVEQRFTDTAVFGLLGADWRLQHGLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM3</accession>
    <name>A9AVM3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase AAA-2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3991"/>
    <dbReference type="EnsemblBacteria" id="ABX06623">
        <property type="protein sequence ID" value="ABX06623"/>
        <property type="gene ID" value="Haur_3991"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3991"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_282837_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4033-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="107"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="386"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="6">
        <location>
            <begin position="559"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="PCRF" evidence="5">
        <location>
            <begin position="757"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="742"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1027" mass="116471" checksum="B182F12263561FE7" modified="2008-01-15" version="1">MGRSGQARRRRRTSRFLEQVGSRRKRAAVAPLQLDGREETAALLATLDELAPLLGEQRIMVEDEELANLLSRCTIDLRARAERDELRPAFLRDEDLLAVQQLLTSMDHVNPIILGKARSGKTALVHELVRRLVKTPENMPEKLRDLPMYEMTPASLLAGLQFGEGWRANLSTLFGKLAEHGAVLLFIRDIHAAVGAGVKRGDDDDDDLAAALESNLHNGKLKIIAEARPDRWQAIAADRESFADLFTSIQLAIPKPEQVAEIVQHVAERHRQRANIEATSQATAIDIAGRFILNQAFPGKAIELLEDSLLLAERQHEPEVLPRHVVECFGNRTGLTKLLLDENERFDEIALRRSFSERVLGQDPSVIAMVQKLALLKARLHDPARPMGVYFFLGPTGVGKTELAKTLASTLFGSEERFVRFNMADYSGEYDFAQLFGRTWGDSDAERRGKLTMALINLPFAVLLLDEFEKAHRSIFNRFLQLFDEGILVNAMGEEINLRNTIIIMTSNFGATIVQGETWGFAAREGIEAVERRVLRETEEFFSPEFINRLDGVIFFKPLSQSDMRKIAAREMRKLFEREGLVRRNVQVELDDAVLDILLKHGYSIRYGARYLKRQIEKMVTYPLASALLTRPEQTNGLLRLYVAREQIKASWVANDDDEPLLPSPEEQALQLPQTIEEAAQFIEQLHNRLKHLIKQLNVVEARERQTELMDEMSSPSFWDDHEQAQFLLTELSNVARRVGRCDDLRRLYDDADQLLQRIRERNERRLFPELMRMAKRLERDLRFAELEMLFSNPEDWHDAYIILESDQAGLRWVRNLANAYLEWSLGKRFEAKVIDETPAEDNLIRVTLQISGSGAFGLLRSEAGTHRISETGGEPRLKTVTQVQITVLPVPTEDTPAPASSDIEMAVMNTRADGYFLRKLRVTGRAIHRYSGAAAFACAGSERAVREMLLSILLGRLAMKQLDDFIQPSDDAWGSVVRSYHLGKRSTIKDPRTEIVHTNPKAALAGELDLFIEAALRWRAALPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT0</accession>
    <name>A9AVT0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4048"/>
    <dbReference type="EnsemblBacteria" id="ABX06680">
        <property type="protein sequence ID" value="ABX06680"/>
        <property type="gene ID" value="Haur_4048"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4048"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_19_1_0"/>
    <dbReference type="OMA" id="RFERWRP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4091-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="134"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="37902" checksum="07DEE15BFC2440EB" modified="2008-01-15" version="1">MPINLALVGFGMASQVFHAPLIMAEPQLTLHTIVQRSSQSARETYPHVQIVSDLAEALANPAIELVVIATPNQTHADLAAQALRAGKHVVVDKPFTLNSQQADQLIALAQEQQRVLSVFHNRRWDGDFLTAQAVIQAGWLGRLVSYECHYDRYRPQLKQAAWREQAGLGSGILYDLGAHLIDQALVLFGMPQSITAQLAKQREGAQTVDYFDLCLGYAELQVTLKAGMLVRELGPRFSLHGTNGSWIKYGIDPQEAALKAGQAPNSPNWGQEPATDWGMINTELNGLALRGTVETIAGKYPAYYCNVAQAIQGKAEIIVQANQARSVIRLIELAEQSAAEQRTMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX2</accession>
    <name>A9AVX2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0562"/>
    <dbReference type="EnsemblBacteria" id="ABX03210">
        <property type="protein sequence ID" value="ABX03210"/>
        <property type="gene ID" value="Haur_0562"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0562"/>
    <dbReference type="eggNOG" id="COG2369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145966_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-571-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="26238" checksum="3F91699A41121850" modified="2008-01-15" version="1">MIDAVAIANQFRAELQAQNASAMDDLTKRWRTVEAALKAEMEALAFQMSQAKADGQTVSESQLYANERYQALLVQLQRELAKYNADAAAIIQAQQLSFASMGAEQATAWLRYSGAIQGSFTQLNSGAFENIAALARADNPLALLLSNAYPETAQAMTDALLSGLALGKNPRITARMMVNDGLATSLNHALLVTRDQSIRASRVAALQQYQTSGLAAAYMRIAARGVPVWPVWRSMARSIRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW98</accession>
    <name>A9AW98_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2108"/>
    <dbReference type="EnsemblBacteria" id="ABX04748">
        <property type="protein sequence ID" value="ABX04748"/>
        <property type="gene ID" value="Haur_2108"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2108"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2136-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05931">
        <property type="entry name" value="FAAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040097">
        <property type="entry name" value="FAAL/FAAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="592"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1669"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2713"/>
            <end position="2788"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="630"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1704"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2820" mass="312947" checksum="D57A47A8A46F9B2F" modified="2008-01-15" version="1">MYFRKPPLCFQNDRFQKAIVSVLEHANLPPATTLVDVLRLNALEAPEQQAYRFLNGQFATEDLSYAELDRRARQVAVRLQALNAQGERVVLLNDPGLDYIVSFLGCLYAGAIAVPLYPPKLQQLERHLPRLLAVVANATPRFALIDRQFVSQIERLLAVAPQLQALQWLICDEKVDAGAWQVPQLETHNLAFLQYTSGSTGQPKGVMVSHGNLLANLAQIQQRFGHDATSQGVIWLPPYHDMGLIGGILQPLYSRFPVVLMSPVAFLQQPWRWLQAISDYRATTSGGPNFAYELCVRKITPAQRATLDLRSWRVAFNGAEPIRPNVLRQFAETFADVGFDPAAFYPTYGMAEATLMVSGAHLPRLAQPEPELISCGTVIDEHELLIVDPTNLEVLPETAVGEIWLRGPSVAHGYWASAELSKATFAAQPRERNEHFLRTGDLGFLRNGELYINGRLNDLIIIRGQNHYAHDLELSVDQAHPALQPQACAAFSLDVAGVEQLVLMQELRREQRQHDPAPIMAAIRQSLAQTHGLQAYAIVLLRPGQLPRTSSGKLQRYRCRELFLGGELTPIAQTIVASVDHDSLDSQQIRALPTTEQPAAIATYLRQQFSRQLGFEVDVTLPIQQLGLDSLAAIDLQYQLEQDLGLVVGFGQLLGQQSLLELADELAQQLHEQTLVVPTIAPSAVSFGEQALWALDRLHPNSTAYTIARAWRFEQPLDPAHFAATWASLAERHAALRTNFVEVDGVVQRVVHAKVESLVRLVDANAWDATQLHDYLQAQAKQPFDLANDRLVQVQLIAHPKGQVLLLLAQHTVVDLQSLAVLLHEAQQLYQALAEQRAWHLPPAADYREHVAWQQAWLASPAGQASHQFWQQQTAEGLPTLELPSDYPRHAQPSQAASYHYLIENSLLNKINAQPQTLLSTLLAGVALLLNRYSQQRQFVLATPTLGRNAQSRSGVGYYVNPVLINWQYQPNLANTELLAYTQNQVLAAFEHQAYPFDLVLRSLQHDRHNPPIRVMVVLQQSPLGQALELGGLALGREQTSMYFADHQAQIIELAPNDLQFDITITFAPLEQGLGLRIDYDQGLFATATIAQWSQHLKQTLEFLVSTPQPMGELSLSTPALVPSQAFETGCLSQWFEAQVAKTPDAIALTDGQQHWTYQQLNQQANQLAHYLHDYGIGAGSLVGLYLERSALVVLSILAVLKTGAAYLPIDPMYPAERVQFMLADADVALLLADARLAEFSGTLIDLKQHAWHNQPTTNLELALDPTQLAYVIYTSGSTGQPKGSLLSHANVTRLFSSSQQHFNFNANDVWTLFHSYAFDFSVWEMWGALLYGGRLVVVPQALSRNPEDFYALLQRERVTVLNQTPSAFRQLIQVDQQRQVNLALHWVIFGGEALDVATLRPWFERHGDSTPRLVNMYGITETTVHVTYRPLSLADTVNYSSVIGQPLSDLQAVVLDANLQPVPTGVYGELYIAGAGLAMGYLRRPDLTAERFMPHPWSNHAGQRLYKTGDLARWNQQGELEYRGRSDQQVKLRGFRIELGEIRAALLAHPAIREAVVDVAELEVAAPIADAQPSQPTLNELRPFIKTAQRQAPTLEQRLVAYVVASEPAPTTISALRRFLRQRLPDYMLPAHLLLLERLPLTSHGKLDRAALPAINQQRPELETVYRAPTTGLEQQLASIWSAVLGVPTIGLDDNFFDLGGDSILSIKLRAQAAEQGLHFSLQQLFANPTLAELAPLVEQSSDQAELIAPFSLISAADRQLLPADIEDAYPLARMQAGVIFHCQLEPNTPLYHDIFIYRIRVAFDADLLRQAVQQLIDRHAVLRTSFHMHGFSQPLQLVQRHVVAPLTIEDWRDLDEAGYQTRQTAWIEQEKQRHFDWQTAPLIRFIVQRASDDSCDLVLSFHDTIFDGWSTASLLTELMLRYDGLLNQQPLDPTPPLVQYRDFVAQEQRVLADPQAQAFWREALADASDTPLPRWPRPAATSAVPDVAVLDVPVSAQLSQQLHELARQAHVPVKHVLLAAHMKVISLVTGQREVISGLETNGRLERHDGEKTIGVHLNMLPFRQYLAPMSWLSLIQQVFAAELALMPYRQMPLAELQRERRGQPWFETVFNYTHFHVFEQLQQLKQLEVIGGRGFGQTHFSLLAELNLNTFTGQLQIDLVGNLHELTPEQLTLIGNCYAQVLAAMVAEPNAGHHLHHHLTAADLAQLQAWNATEQPLAYASLVTAFEQQALQHPHALAVVAADQALSYAELNQQANQRAHSLRQRGIGAEMLVAVCVERTSDLLISLLAVLKTGASYLPLDPSYPPARVNWMLADSQAALLLTQPQFTALFADIQIPVCYTDEQHTSTANLASAIEPSQRAYVLYTSGSTGQPKGVAISHAALSNFLQSMQTQPSLQPTDRLLAVTTVAFDIAGLELYLPLWVGATVVLAPANAAAEGFGLAELLQSHQITVLQATPSTWRILLATGWHAPTGFKALVGGEALPSDLAGQLLSAGVTLWNLYGPTETTIWSTAAALSQTPVHAGRPIANTEIYILDQALQPVPLGTPGDVYIGGLGLARGYHQRPNLTAERFIPHPWSQQTGARLYQVGDRGRYLPDGSLELLGRSDQQIKLRGHRIELGEIESALRTLSTIQQAAVAVWNEQLVAYVVADHHFEPAEVQQQLSQQLPVYMLPRSYQRLDALPLTANGKLDRRNLPAPDQALVPETHGYVAPTTGLQTELCAIWAQVFGIAQVGIHDDFFALGGHSLLATQLIIQFRQRFFVDLPLAQLFNAATVASLATLIEQLQADQGQTAELAALLDELDQLSDDEARARLLADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW99</accession>
    <name>A9AW99_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MbtH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2109"/>
    <dbReference type="EnsemblBacteria" id="ABX04749">
        <property type="protein sequence ID" value="ABX04749"/>
        <property type="gene ID" value="Haur_2109"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2109"/>
    <dbReference type="eggNOG" id="COG3251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181321_0_1_0"/>
    <dbReference type="OMA" id="RADCVEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005153">
        <property type="entry name" value="MbtH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038020">
        <property type="entry name" value="MbtH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037407">
        <property type="entry name" value="MLP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38444">
        <property type="entry name" value="PTHR38444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03621">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00923">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160582">
        <property type="entry name" value="SSF160582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MbtH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="71" mass="8059" checksum="281D2DC19C526FD0" modified="2008-01-15" version="1">MQTTDDDTTIYNVVINHEEQYSIWPAERENPLGWSNVGVSGNKQTCLDHIKAVWTDMRPLSLRQALANQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD8</accession>
    <name>A9AWD8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2148"/>
    <dbReference type="EnsemblBacteria" id="ABX04788">
        <property type="protein sequence ID" value="ABX04788"/>
        <property type="gene ID" value="Haur_2148"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2148"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2176-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15923" checksum="A26A67F177B39EDD" modified="2008-01-15" version="1">MSLIQKMTKAFVLIVEDNIDNMLVLTELLNVMPEVRYCNVRPSGRQLFAFLENDAVPAINLILLDINLPRENGYVLLPKIRVHPKLCNALVIAVSAQTGPQEVAKIRAAGFDGFLAKPLHFQRFPEQLRRIMNGEQIWEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE9</accession>
    <name>A9AWE9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckA</name>
        <name evidence="9" type="ordered locus">Haur_4076</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4076"/>
    <dbReference type="EnsemblBacteria" id="ABX06708">
        <property type="protein sequence ID" value="ABX06708"/>
        <property type="gene ID" value="Haur_4076"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4076"/>
    <dbReference type="eggNOG" id="COG1866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018247_0_1_0"/>
    <dbReference type="OMA" id="MRYAGEM"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="231"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="526" mass="57205" checksum="B491FEEE42220641" modified="2008-01-15" version="1">MTERAVLSEGDTVGANLHVKQAYRNLTVPQLVEAALKRGEAVLSATGAVVATTGARTGRSADDKFVVETPAAASMHWTKFHKAMKPETYATIKAKALAHMAEREMFVLDASAGADPAYALPIRVVTEYAWHNLFAKQLFRDAISSDQQPQWTVLNLPSLKLDPAVDGSRSEVAAMINLDEKLILIVGTEYAGEIKKSIFTVLNMVLPSQGVMPMHCSANIGSKGDVALFFGLSGTGKTTLSADPERILIGDDEHGWSANGVFNFEGGCYAKCIRLRRESEPEIFDAIRYGAVLENVVLSDSRDPNYDDASLTENTRAAYPLEYIPNVSETGMGGQPETIIFLTADAFGVLPPIAKLSPEQAMYHFLSGYTAKLAGTETGVGSEPQATFSTCFGAPFMPLHPTVYADLLGQKMREHKVRVFLVNTGWTGGSFGVGKRMSLRDTRTMVHAALAGKLDAVEMWHDERFNLDVPVAIEGVDNSVLQPRQTWADASEYDRVADDLAARFRKNFEQYAERAGETVVNAGPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH3</accession>
    <name>A9AWH3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydroorotase</fullName>
            <shortName evidence="5">DHOase</shortName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrC</name>
        <name evidence="8" type="ordered locus">Haur_4100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4100"/>
    <dbReference type="EnsemblBacteria" id="ABX06732">
        <property type="protein sequence ID" value="ABX06732"/>
        <property type="gene ID" value="Haur_4100"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4100"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_1_0_0"/>
    <dbReference type="OMA" id="QHAQEPR"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="57"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
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            <begin position="68"/>
            <end position="70"/>
        </location>
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    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="347"/>
            <end position="348"/>
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        <location>
            <begin position="450"/>
            <end position="473"/>
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        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="68"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="100"/>
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        <ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
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        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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            <position position="333"/>
        </location>
        <ligand>
            <name>substrate</name>
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        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="473" mass="50768" checksum="D2A3BE5FAD463113" modified="2008-01-15" version="1">MSRIVIKNGCIIDPARKTATVGDLVLENNRVREVIELAMAPDSYGDDVEFIDASGCFVTPGFIDIHTHLREPGFEGKETIATGMDAAVRGGYTTICPMPNTNPSLDSAPLIRQQFDIAARHGPIHVLPIGAVTLGREGKVLAPLVELAEAGAHGFSDDGSPVWDAHIMRQALLYSKMTGRPVMNHCEDLSIVRGAPMNEGAVATRLGLSGWPAAGEEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHLTMTDRWVLGSMEPWDGKGPYDPSQLAPYDTRTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKECEYGFASPGFTGLELALPMVLTLVQTMQIDIVELISRMTIGPAAIIDVLPISLGPNDPATLTIFDPAAIWKVTPEALASKGKNSPLMGQEMRGQVMLTMMEGQIVYRREQFGESSRREHGGAVGKLSGVFDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN9</accession>
    <name>A9AWN9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4166"/>
    <dbReference type="EnsemblBacteria" id="ABX06798">
        <property type="protein sequence ID" value="ABX06798"/>
        <property type="gene ID" value="Haur_4166"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG0457">
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    <dbReference type="OMA" id="QRYPNDS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4212-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
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        <property type="entry name" value="TPR_repeat"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX06798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="390" mass="44377" checksum="E592355601C10EB4" modified="2008-01-15" version="1">MADKFRQAELHYRRGLSLEHAGRIAEAVEEYRQALQENPQLRAAHVALAKYYLRNGLLAKAADAWHAVVAIEPDYEALTNYATVLIELKHYHEARQILRLCVELFPLDTFVTYELAYIDFAEGLYQQALDQLLDVRPIYNDEWEFHELIGRCQIKLQLYDAALASFGRAILLVDDDEQIEQLQDLGSIARRYQEFSLVSNEKDAWYATHGLICLGSNLDNGLNLKPQAEFAWSFEAIATTLQRAAALAEAHVWRCDQVLAFDSQSKPLAQALAQLLQRPYIQKIGDPEKITLVVMAEFEQSAMLEAIAEQLDGLHCIFALSMRTSPDLLDDIPDLIGLPIQKPSLPWTSQSIATATKTLLATLAQLTPEPNREQQLDYYREQHRLIRLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWX1</accession>
    <name>A9AWX1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0724"/>
    <dbReference type="EnsemblBacteria" id="ABX03372">
        <property type="protein sequence ID" value="ABX03372"/>
        <property type="gene ID" value="Haur_0724"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0724"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_562399_0_0_0"/>
    <dbReference type="OMA" id="EISHTTI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-736-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="225"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="499" mass="53538" checksum="435D5C79BF23D82A" modified="2008-01-15" version="1">MANLGSLFSLDFTNLADRRRVIMRIVALAALVVPFLVVLVAWIYERNNPQLWDALGVLFVSMGAVWLIALFSLRMINQGQDQIVTYVLIGTISLSALACAVRYGGIDQSLIVSLLLVMLFIVGLVATWREIVSYGVTITLAYGLLLLFKSNLESFQVTTLTAANNAGVYGVGAVLFFVGLATTIVLTTIFSRALAEYSQKSEQWTADLMRANEQLIEKNIQQIELGTDLSFAATELSAASQQQASGATEQASAVAEVSSTIEELGFTARQIASASDQVSIAAQQTLTSLAMGQQSVDEAIQGMERIKQRVQEVSSRVLSLGERSHHISEIIALIDDVSDETHLLALNAAIEAAGAGEHGRRFAVVAAEVKSLANRTLAASREVKDVIAEIQAATNASVLATEESVKEVEQGVSLAHRAGQEMDSIVVLGEHTAQLAQEISLATAQQQTASEQVVETMREIAEVSRQTAAGSRQTADAASKLTAIANRLHSLVNIEAHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ0</accession>
    <name>A9AWZ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2158"/>
    <dbReference type="EnsemblBacteria" id="ABX04798">
        <property type="protein sequence ID" value="ABX04798"/>
        <property type="gene ID" value="Haur_2158"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2158"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333640_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2186-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="139"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="856" mass="98763" checksum="8D8F360F2C454122" modified="2008-01-15" version="1">MTQSTLQWNDAVVHDLLHYPQRLLQHHAWSAVIAEAGGLQQMRQQLLDFPLKAKERRVLEVILNNPEDSVVRYTDLLAIHHATFHRQQNALCRSLSQFLNTVQAPAEPQVLATPVANPVSFVVPWTSFIGRHAALTTLKTLLADDHRWITLIGAGGVGKTRLAMELAQQSIGSCCDEVHMLRFADVQRVEDVGLACIQQLQLVITEAQSLEQTLQQFFQQRRSLVIVDNLEHIPAAGLWLAQVFQAVPQQQVIATSRVRLNVPNEQLYEVAVLDCPAEKASFEQLNQSPAVQLCLDRMEAVRLVDRTNHQLLDLVGQICRQVAGLPLAIELVAARTAEYSLETILAAITTDLEFIAEGPLDLDARQQTMAATIGWSYQLLPAQSQHIMQQLAVFRAGWDAAAAAAICGLEPELMEDHLALLLDNHLISYRLDSEQQPYTILEPIRQYAWQLSPAEQQHQLRSQHCDYYIIWVAPSEEIMLGPDAAFWHCAFLQSYPNVQLALHTAKADPTPRRFWQLLGSLYRCWWNFQLIAEAQSWLEPTIPVVLQPTSEPYLQCRVLYSILLFCAKDTASYSRLATYHYLINLAHHNQFYVLEAKAKNFYALILMEQNKLVEAGDLLLDAATIYRQIGDEDNFLTPMLNYANLLYKTKRFEQACDIYDELIIKFEAIKDYDGMYSSIKNVAVIYVCQEKYYEAEEKFLYLIKQAEDRKNIDIYLGDFDIYLRLIKIYSFLRRADDIDIYVHKLYPISMGSLFFIEQVFTLCETIIYIAIFKEYYLVAYSAYIYLLNILYLEHYEMRWYESEFLERTKIILNQYCEDFDALIDADFYWDLNSFNDTMNYFLRIIYGFHSNSYSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ9</accession>
    <name>A9AWZ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2167"/>
    <dbReference type="EnsemblBacteria" id="ABX04807">
        <property type="protein sequence ID" value="ABX04807"/>
        <property type="gene ID" value="Haur_2167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2167"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699753_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2195-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="394" mass="44914" checksum="0D41860D8E82F836" modified="2008-01-15" version="1">MTIIPVLAHWNSDALLAMPFDQYQRYRVSAEAICLLKEAAGASDQPWRILDVGGFFPPRNGVMPLQAFFSNDQTLVVDTAEYVGAGYQQADGTQLPFDDQAFDIVLSCDTLEHIPLEGRDSFLAELRRVARRAVFLAAPHALTNVATSEAMLRQYLTQLQMNNPMLDEHVHYGLPQSSLVEAWLASEKLDYLAFESGYLPHWQLLMVLKHLLFRQPQRDAMHANFDALYNQRFYEYDQRGPGYRRIYLIATTGQLAPSLQALVERSLRPTPTNPASDLLSIVLPVLTSTAYDTVLFQHNLTTRLDGFEQQQQTQTQLLQQTLERHATTIEVVRDLERRLLDASVLAAQLEAEKRGVQAQLDYVHWQHSLLQQALNRSLAQRIATGLRQLLRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX25</accession>
    <name>A9AX25_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate-binding family V/XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2193"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04833">
        <property type="protein sequence ID" value="ABX04833"/>
        <property type="gene ID" value="Haur_2193"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2193"/>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_355190_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731696" evidence="2">
        <location>
            <begin position="26"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="3">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="790" mass="83270" checksum="13D791E43A38E931" modified="2008-01-15" version="1">MQRFFSLMLVFSLFASLLFNQATHAAPNPWAANTAYAVGSQVSYNGTIYECLQAHTALVGWEPATTPALWKQVSTAPSATTIPATSIPPTAPPATNIPPTATATPTAGCLNPAAGVGWQSRSLSNQTGNFSLSFEATLSASPTNAVIGLANAVPTDYTGLAIAVRFNPTGSIDARNGGTYAAATNVAYSANTRYRFRIVINLVAHTYSVYVTPQTTSEVLIASNFAFRSEQANVSNLNTLATVVGGTGAVGSLNLCNISLNLPATPTPLPTATPTPRPTATPVPTATPAPTGYTPAFCANYPPAIVAGSWQSSVVSYHNGRLQYTNDSAQNRIPDFSYAGYYSGQRPLPNLAVVQTLSPISGDNTARIQQALDAIGNRTPDANGLRGALLLAPGRYNINGTLRINKSGVVLRGSGDGSDASTSTILLGVGNTPHQRTLIVVGNGDSTPWTAGSATNVTDQFVQVGSKSLNVADPSRFTVGQEVIVRHPSSQAWINAVNGGGVVNDAWWAVGALDMTWTRRVTKIAGTTLTLDAPIFNHLDRALSQATVAPVASRTIIANAGVENLRVDIQTAGGEDENHVWDAIGIVGAENSWVKNATVLHFGHAGVFTQGAIRITVEDVQALDPVGIRTGGRFYNFDAESNSQLVLFTRVHATGGRHNFISNGTQTTSGIVWHRSTEGGGSDSEGHRQWSQGLLFDTINASAASNIKLINRGDYGTSHGWGNVHSVIWNYNRTMMVQKPPTGQNYVISQAGTRSTSYPFPGAGGFADIRSGSLVPNSLYEAQLCDRLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX32</accession>
    <name>A9AX32_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2200"/>
    <dbReference type="EnsemblBacteria" id="ABX04840">
        <property type="protein sequence ID" value="ABX04840"/>
        <property type="gene ID" value="Haur_2200"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2200"/>
    <dbReference type="eggNOG" id="ENOG5033F66">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1658231_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2228-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20173" checksum="E4369DE5BF916406" modified="2008-01-15" version="1">MQTFFQQLRQPKQSLAQQLDQPFQQWPYRAWLLHSSLAVGGSLIFGGSLNRALPRWSQRGAAWWLTLSSGAGWLVLGPALLLASRGNINSCIQACLVSMSYGETILLIAALLNYVLKSQAYAQQRNLLLVLIANLSMATALAEQLSMIKLARWQTWLLWMLLLNGTGAVCFYRLRHLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXG9</accession>
    <name>A9AXG9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4257"/>
    <dbReference type="EnsemblBacteria" id="ABX06889">
        <property type="protein sequence ID" value="ABX06889"/>
        <property type="gene ID" value="Haur_4257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4257"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_578436_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4304-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="4">
        <location>
            <begin position="103"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="124"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="469" mass="52147" checksum="D273E7B4B4B5B862" modified="2008-01-15" version="1">MDAEALQIGALILAMALVALMFRQRFGRDWREFRLWQAQQRAVQPEPTNISQFKPLATSLDPRTLPEAGTALLNPPHDLRVLAHELRQTNKRFVLPLGWRSVQGVVSLVHGSLIDDFTHVQVSGATGSGKDGWVRTALFYLCLTNPAERLQLALVDGKAGLSWLGWREKAHVGLFAEAEHELAPALTWLTQQRLERQTLLKAAECERWEEYQGHDLPLLVVFISELTLLEQAIGAKQLEQWLNSELTSGRAAGIRYIIATQTFSNLSTRFRSQISLAVAGYQPRDDADEPNTTLPTKAFPSSAVPPSRLPSPPAGAGVFSCVQGRNAVTVRTSFIDKTQRQQLLSLLPDRQQALPTLEAAPIKAANLPIATEQPLIALAQTPSQSYNRYDLAQLLLQYLNRPDQLLDAELFRNACSIEYKRLRSYAGVARLFWGKDAAPNKSRLIKQALERQATPNEQDMLANLLGTVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI5</accession>
    <name>NUSB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nusB</name>
        <name type="ordered locus">Haur_0751</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXI5"/>
    <dbReference type="SMR" id="A9AXI5"/>
    <dbReference type="STRING" id="316274.Haur_0751"/>
    <dbReference type="EnsemblBacteria" id="ABX03399">
        <property type="protein sequence ID" value="ABX03399"/>
        <property type="gene ID" value="Haur_0751"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0751"/>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087843_3_2_0"/>
    <dbReference type="OMA" id="DRMPVVD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0889">Transcription antitermination</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000192444" description="Transcription antitermination protein NusB">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <sequence length="146" mass="16045" checksum="B8845C26467EB5D8" modified="2008-01-15" version="1">MSSRTVGSLRHRVRAAALQALFELDQTTHDLDSVVARISDDEMFSAEGRDFFARIVNGAWVNRQEIDDLIAKIAPSWPVHQMPGVDIAVLRIALFEILYDAAADKAPVKAVINEAVELAKHFGSDNSGRFVNGVLSTVVNKPESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXM0</accession>
    <name>A9AXM0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0786"/>
    <dbReference type="EnsemblBacteria" id="ABX03434">
        <property type="protein sequence ID" value="ABX03434"/>
        <property type="gene ID" value="Haur_0786"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0786"/>
    <dbReference type="HOGENOM" id="CLU_2508180_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-798-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9999" checksum="7736B3C72EBE2B17" modified="2008-01-15" version="1">MNKLKQAYLQLAVERDRTRRQAERYAHESQRWTERLALAKRCGEPELATQARERALQTAQAEIQLRRELVRQEVLVDQLIASLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN1</accession>
    <name>A9AXN1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0797"/>
    <dbReference type="EnsemblBacteria" id="ABX03445">
        <property type="protein sequence ID" value="ABX03445"/>
        <property type="gene ID" value="Haur_0797"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0797"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_1_0"/>
    <dbReference type="OMA" id="VIRTERM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-810-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="248"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="44982" checksum="DC4F94B6D9CC3F45" modified="2008-01-15" version="1">MALDQPTVALIVGIGLLLQALVIGAFLVFVRRYQGIRCFLIGTIGLGLGFLALALLPQTSIVAITSSYILILSGLFGLSSGILRFIGAASSAKIYAICWLIVASMLSLCAWLFADSGLIINLAMLIGSAGMAYTALQVFFQRTIPYQSASRLLALALTLKMAFVVLGLAYFWYSQRWPSLTTLKLGYSVLILLLSLLWTGGFAVMITQRMQCDLSALASIDVLTGIANRRAINEYLEQAIAKWRRNQQGFAVIMLDIDCFKQINDRYGHHAGDSVLRHIALVLSEQVRINDLIGRWGGEEFLLIVDADTIQQATLMAERLRQAIQQQPTVWNDQVIQHTVSIGIAVCGMHGFNEAQLLTAADLALYEAKETGKNRWIVYERRLLNQLDPTLELANEGLIFDVDSSIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP8</accession>
    <name>A9AXP8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0814"/>
    <dbReference type="EnsemblBacteria" id="ABX03462">
        <property type="protein sequence ID" value="ABX03462"/>
        <property type="gene ID" value="Haur_0814"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0814"/>
    <dbReference type="HOGENOM" id="CLU_1439270_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-827-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="22209" checksum="921E92F010710D47" modified="2008-01-15" version="1">MDYLGLIALFAGIFGLTGYAGLLLRQAIGLYRQRPDLRRTLRPVLLNLIEPFVSLLYLIPCMLWWDYGYLLSLVGSDFAAGSIVFAYHWPMQLLLVYAPFGWMFARQKMVARTAWLCFALGVIRVTMLWLCFNYSLGGGMIVLALIVGAATFWLLGRYLQWQAIPPPQIPIMVNIDEQGLVLIQPIEPNQAHQAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ6</accession>
    <name>A9AXQ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0822"/>
    <dbReference type="EnsemblBacteria" id="ABX03470">
        <property type="protein sequence ID" value="ABX03470"/>
        <property type="gene ID" value="Haur_0822"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0822"/>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_548327_0_0_0"/>
    <dbReference type="OMA" id="FWNGYLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-836-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="497" mass="52572" checksum="8046440D999BF6EF" modified="2008-01-15" version="1">MQRRRWILISISLTLLLASVGLSMARTTGFLNEPDCVVSDCTFLPLALKNSSEITPLPTTAATATSAMLSPTATSSTTPTDTPLATNTPTDVPTATSTPTDVPTATSTPTDVPTATSTPTDVPTATSTPTDVPTATSTSTNTATPTSTSTPTSTPTNTATATPRPPTTTPTTIVGTATPTTPPNFTRIVWSTAVPTPFSYPFAAVEAQGAVVGGKLYVFGGFGQPGLSGDTPSRLSNVYDPVANTWTAIAPLERGLTHVGTATDGQKIFLVGGYIEDFDGVGQIFGSRVSRYYDTATNTYTNLPVIPIQRAAGQLYYLDRKLHYVGGTYYKQVDVGTHFVLDLNDLATGWVTQTNQLTYAELPNPRQHAGGVVLDGKLYYIGGQHGHDGSLTVDNDVHRYDPATNMWEQMADIPLALNHISHSTLALGGKIFVFAGQTTNGTKHNTIYVYDPATNTWAQMPNNLPATRYSGIIGEINGTLYFTTGGGTNSYRGIPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY5</accession>
    <name>A9AXY5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04951">
        <property type="protein sequence ID" value="ABX04951"/>
        <property type="gene ID" value="Haur_2311"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2311"/>
    <dbReference type="HOGENOM" id="CLU_1298371_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2339-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="25420" checksum="0CB04FAC1A137246" modified="2008-01-15" version="1">MTDAIEQLASKLSVENTEIEDFLQELSVRFDQSVTAEEVLGLIEPFKKIFSFATLTQHIEQKLINNYIHKNNHLINEFKNKKLDNINLFKSRIILYNKITNYSNKDIFELHIFLNKNRYITDLHLKDTITYLSKMNIVQTYTFEYIQLVAKFRKPNFPFKNPDLLINNIFYKTGLKINIQQLLSIVENYNTAFEFLDYCYIYIFIYYKIYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXZ5</accession>
    <name>A9AXZ5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4268 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04961">
        <property type="protein sequence ID" value="ABX04961"/>
        <property type="gene ID" value="Haur_2321"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2321"/>
    <dbReference type="eggNOG" id="ENOG502ZAEI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064448_0_0_0"/>
    <dbReference type="OMA" id="FSVELYI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2349-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025364">
        <property type="entry name" value="DUF4268"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14088">
        <property type="entry name" value="DUF4268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4268" evidence="1">
        <location>
            <begin position="179"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="37877" checksum="6355D4A7BC9B9CE6" modified="2008-01-15" version="1">MNQLGRLKRVPIHDAWRQAASHFTHWLTQAENIAQLNTATNLELRFEALNKGTGNLRQSLVCYDRRTETKVLIENQLAGSDHAHLGQLLTTASTVKATILIWIAEHFTPEHRATIEWLNQQTLPHLLFFAIELELWQIDDSPFAPHFKLICKPADWELAITNEPVPVAPPAPASPSKNIYLGYWMRFNAMLRERNSHLGAKKPHSEPSTSFALGRADCSLQAVLNQRDNWIGVAVMLSGISAKLRFRWLRQQRVAIEQQLGVGLEWRENPLTKEYQIWLIRRNANLHDHQHWADHHVWMIDTLERFYRVFTPLLKQLYIRNEPEHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT8</accession>
    <name>A9AYT8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2426"/>
    <dbReference type="EnsemblBacteria" id="ABX05066">
        <property type="protein sequence ID" value="ABX05066"/>
        <property type="gene ID" value="Haur_2426"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2426"/>
    <dbReference type="HOGENOM" id="CLU_1281746_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2454-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="215" mass="23259" checksum="BD1AA1F3F017FD2A" modified="2008-01-15" version="1">MGRLIGIFSLIVILVGCTEQPAAPASNQITTAPTMIQASPAVAPLESTSTPSTTEPVSLTFTTYRDPRGVFAIDVPSNWRTESLKNGIGISSFAYNASVVVTISFSWQAEQLDSTKAAEIVEMVKSQTFATYLTRDVQLNSASEGATYRLEGTASLNAQPMYVRFELSQTTGGSIMLQSWLVPQDLWPDVETTFYTPMQRSLSIDDEAAAALAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ00</accession>
    <name>A9AZ00_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="9" type="ordered locus">Haur_4408</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4408"/>
    <dbReference type="EnsemblBacteria" id="ABX07040">
        <property type="protein sequence ID" value="ABX07040"/>
        <property type="gene ID" value="Haur_4408"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4408"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_1_2_0"/>
    <dbReference type="OMA" id="MSPVIAW"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="60"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="24563" checksum="530271D1B3114994" modified="2008-01-15" version="1">MKPLNLILFGPPGAGKSTQAAYLDKLAAIDSISTGQRLRQTVETGSELGQEVAQVMAEGRLVDDTLMNKLLNEWLLGIPSEVGVLLDGYPRTLSQAQSLDQLMQTISRPLDVVIALTLSDEEAIRRLSGRRICRIKGQPDQILHINDQAALDACRANGGMLIERDDDKPETIKRRLAEYNAKTEPLLQFYGERDLLILIDADGTPDQVSKAIEQALQQRFNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ28</accession>
    <name>A9AZ28_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4436</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4436"/>
    <dbReference type="EnsemblBacteria" id="ABX07068">
        <property type="protein sequence ID" value="ABX07068"/>
        <property type="gene ID" value="Haur_4436"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4436"/>
    <dbReference type="eggNOG" id="COG0392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048072_3_0_0"/>
    <dbReference type="OMA" id="IVDMEHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4491-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="42709" checksum="C1F42DAAE832B69C" modified="2008-01-15" version="1">MKSQTQANPASLRPEQTNQGLPRPAETESLEQLVEQAAEAAPLPADALPDDLAEVRSSGFSLRDKFLNVKSLASFGIAFAILGLAFWRADINLAEMWQQILQTNLWLYSAGFIVFYGLFPIRAWRWRIILRSAGFEVDSPQSRKNWSGIAALSEFIGLSWFANCVVPAKLGDAYRGYLVKKNGNASFSRTLGTIFAERIVDMIVLFGMLVVSGLLVFQGHLNSWTEKLFIIGIVFTILLVIGLMSMRYLSPLIRRALPQRFHDFYARFEEGTLSSFRPSRLPILLILTIIVWLGESMRLFFVIEAMGGLGLSLSAIIFVALASSLLTAVPALPGGLGLVEVGIAGVMMLFSVGQTTSTAVAFLDRIINYWSIVILGLVLYLFSKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ69</accession>
    <name>A9AZ69_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0967"/>
    <dbReference type="EnsemblBacteria" id="ABX03615">
        <property type="protein sequence ID" value="ABX03615"/>
        <property type="gene ID" value="Haur_0967"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0967"/>
    <dbReference type="eggNOG" id="ENOG50335F4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2144156_0_0_0"/>
    <dbReference type="OMA" id="VWLANDK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-981-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="13191" checksum="056B50F6A6B409B9" modified="2008-01-15" version="1">MGAFNTLHLQAPCLSCGVEIPLVLQFKYAENWQHEYKLNDQLRWNHRYRRANDGKPGMTHVVVSAIAETCPLCQYDGDDYLIHVYNDVLTSVELDDQRYNFQNSEGYFFVLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ79</accession>
    <name>A9AZ79_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD40 domain protein beta Propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0977"/>
    <dbReference type="EnsemblBacteria" id="ABX03625">
        <property type="protein sequence ID" value="ABX03625"/>
        <property type="gene ID" value="Haur_0977"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0977"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_879334_0_0_0"/>
    <dbReference type="OMA" id="WIAYVAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-991-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="34552" checksum="C458D18562F49118" modified="2008-01-15" version="1">MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINRGTIMISGLDANPPQLLNPDFPLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQVTNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSNLRQLTNDPARDWQPSWSPDGSLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGGDVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSVPITMADTDLIQPVLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ84</accession>
    <name>A9AZ84_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxygen sensor histidine kinase NreB</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Haur_0982</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0982"/>
    <dbReference type="EnsemblBacteria" id="ABX03630">
        <property type="protein sequence ID" value="ABX03630"/>
        <property type="gene ID" value="Haur_0982"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0982"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_6_0"/>
    <dbReference type="OMA" id="PLDIEWD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-998-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="19">
        <location>
            <begin position="61"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="18">
        <location>
            <begin position="141"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="117"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ABX03630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="37485" checksum="5CEE17772FD4452E" modified="2008-01-15" version="1">MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVLRVALRPLTNLQIAAERVTDGDLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERSRALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIYAETAAQNPQAQAVRERLIGLRDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPSAVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDGRGVGMFGMYERVNLLGGTMAIDSAPSIGTELTITVPLEPATQASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ95</accession>
    <name>A9AZ95_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0993"/>
    <dbReference type="EnsemblBacteria" id="ABX03641">
        <property type="protein sequence ID" value="ABX03641"/>
        <property type="gene ID" value="Haur_0993"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0993"/>
    <dbReference type="HOGENOM" id="CLU_1693088_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1009-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17310" checksum="9550557FD983B7A0" modified="2008-01-15" version="1">MLRGYFVPSLKPNPLPIKLIAGYQFATALFGCYALFWALQQGSGIVDPLSGGSTGVDLLQHWLQTDHWLALVFIGAIGVAITIHSLLGVGLLKKYPFARNATIWWDWTVIGLAGFSLAQSNWYFWIDAAVIAISYLIIHYLQQPEIMEVFQPEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF8</accession>
    <name>A9AZF8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2464"/>
    <dbReference type="EnsemblBacteria" id="ABX05102">
        <property type="protein sequence ID" value="ABX05102"/>
        <property type="gene ID" value="Haur_2464"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2464"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_3_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2491-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="2"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14548" checksum="D0E31549511FF84E" modified="2008-01-15" version="1">MNACPFCDPETLEIETMLENRFCRFLQQPDKVLSGAGVIIPKRHCETRHEMDFDEWDAMQELLNQVKAFITTSHKPLGYTIGWNCGAVSGVVIHHVHMHVIPRLTNEPIKEQIQFSLKPTTADRFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ1</accession>
    <name>A9AZJ1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05135"/>
        <property type="gene ID" value="Haur_2497"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-2525-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="AhpC/TSA"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17429" checksum="4669CCDE872CF60B" modified="2008-01-15" version="1">MSDLKLFTHDYRPTLWHKLNQTQPIVAIFFRNLACTMCQGMLRVLEGYQEQFRQFQAQPVVLAKTNPASLAGFIQHFRPQYPMLSDPSGDVFRAYSNASEQLEFQGGILVLPPRSITAVFRFVPQGLEQQVPINELLECIKTLNYYRSSITA</sequence>
</entry>
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    <accession>A9AZM9</accession>
    <name>A9AZM9_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX07083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4451"/>
    <dbReference type="EnsemblBacteria" id="ABX07083">
        <property type="protein sequence ID" value="ABX07083"/>
        <property type="gene ID" value="Haur_4451"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4451"/>
    <dbReference type="HOGENOM" id="CLU_1487126_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4506-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20503" checksum="806CE0624D903E5B" modified="2008-01-15" version="1">MVCWIIIGFMVITAMLGGYFWLNQSEPRPIPPAGWQTIHQDTLIVSLPPEYIVLNPNLASANLDFTKTYSGTYETLTKITNAPVKIDFLAVNPENGDTIVVFDKTFNKNSTLLSEQLIDISDLMSSIRNHNQQTTDTFVTSRLITKYDRELDVQKISESNQNEESKNIFELIGQNIVLEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ2</accession>
    <name>A9AZQ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4474</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07106">
        <property type="protein sequence ID" value="ABX07106"/>
        <property type="gene ID" value="Haur_4474"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4474"/>
    <dbReference type="eggNOG" id="COG3183">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_893734_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4529-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="31670" checksum="3C10EE7D2E6C7ED8" modified="2008-01-15" version="1">MTILQKVDQATIYVYVTDTKIMRPINQGYQKLIVHYVYTTKVRNYLVIAYKEKGYKKERFIDDNSTAVIVKDWDTPDLPDNLKIIQSDEITSTYEMRYGFNSNEWIEEFNSIIDPWIQSNPERLILDLRKQSIQNVSTVEEDWSAAIQANLFDLPSTQPHQPIASPEIFIEGAEYQSLVTRYERNPEARQRCIEHYGSTCVICHFDFAKVYGELAKGFIHVHHLKPLATIGENYEVNPIDDLRPVCPNCHAVIHMRKEPYTIDEVRNMLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR0</accession>
    <name>A9AZR0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4482</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4482"/>
    <dbReference type="EnsemblBacteria" id="ABX07114">
        <property type="protein sequence ID" value="ABX07114"/>
        <property type="gene ID" value="Haur_4482"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4482"/>
    <dbReference type="HOGENOM" id="CLU_1480120_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4537-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="19857" checksum="4F8EE4D348FF5065" modified="2008-01-15" version="1">MRQIWRGVGLGLVLLSFVGCSFESKFLNQRAIDQVLQNEQASLLHTINTTSNTVVFLQTPTGKTCRVFTGGSSDSGFSQSHEGIYYHSSGNQVVVLNIVRHSTVPAEDIFCIAIEDQQLQQQTQTITIHQSNGQTASISTNGAAYSITVLAGNQQSSTGEYLKVEFFDATGKLLHTETPTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS6</accession>
    <name>A9AZS6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4498"/>
    <dbReference type="EnsemblBacteria" id="ABX07130">
        <property type="protein sequence ID" value="ABX07130"/>
        <property type="gene ID" value="Haur_4498"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4498"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_2_7_0"/>
    <dbReference type="OMA" id="NRIINTW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4553-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="194" mass="21790" checksum="9B1DF1A6A34AB76E" modified="2008-01-15" version="1">MTPTIINVGYDETNYYLIGATEGFLMLDVGWPGSLAKLMAQLNRQAIAFTTIRYLLVTHYHPDHAGLVQELKAQGVQLVVIEQQRFAIPILKTYIKPQYHYQEITFDQTIVLRIEDTRQWLASIGIAGEIILTPGHSDDSVSLILDNGIAFIGDLHPYANSDENPALIEQSWQELQKRGVTLLYPGHGGTRPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS9</accession>
    <name>A9AZS9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ordered locus">Haur_4501</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4501"/>
    <dbReference type="CAZy" id="GT5">
        <property type="family name" value="Glycosyltransferase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07133">
        <property type="protein sequence ID" value="ABX07133"/>
        <property type="gene ID" value="Haur_4501"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4501"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_18_2_0"/>
    <dbReference type="OMA" id="TWCPWYM"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="2"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="274"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="460" mass="51422" checksum="6873F960C0361845" modified="2008-01-15" version="1">MKVLFLAAESVPFVKVGGLGDVAGALPEALRRRGLDVRLVIPRYGTIDPLRWNLGQLRDNFPVGLDWRSEECQLWATADQQTWFIENQYFFGSRTTIYGHGDDDVRFALFCHAALEACRQMDWWPDVIHAHDWHAAAAIRIAWGNAARPALVFTIHNLAHQGRFANDAWPLVGVYDAFGELNLMEQALYTSDVITTVSPTYADEIKRPEYGFGLDHMLRERSDRLVGILNGIDPRHFDPATDQHIAQQFSIDDLAGKAVCKAALQREVGLPERADVPLVAVVSRLDSQKGIDLIVQGLGRIIAETDAQLMVLGSGYGPYEDAFRDASRFVPERVANYIGFNAPLAQRVYAGADIFLMPSAFEPCGLSQMISMRYGTIPVVRATGGLVDTVPDMSQPEGVGVVFSDYNVDAMLHGLGRALAAYRYPNDWSYFVRRAMTHDFSWDTAATRYEDVYRWALSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZT9</accession>
    <name>A9AZT9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4511"/>
    <dbReference type="EnsemblBacteria" id="ABX07143">
        <property type="protein sequence ID" value="ABX07143"/>
        <property type="gene ID" value="Haur_4511"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4511"/>
    <dbReference type="eggNOG" id="COG0334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025763_1_2_0"/>
    <dbReference type="OMA" id="PCFAAFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4566-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="184"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="46160" checksum="CD615EF243B1F93D" modified="2008-01-15" version="1">MADSHRNAFENAQRQFDLAAEKLNLDHSLRRVLRVPQRELSVNFPVKMDNGEIQVFSGYRVQHNVSRGPAKGGIRYHPAVDIDEVRALAMWMTWKCALVNIPYGGAKGGVIVDPTKLSQSELERLTRRFATEISILVGAEKDIPAPDVGTNGQVMAWFMDTISMHRGYTVPAVITGKPVEVGGSLGRVEATGRGVSIVAREAAKHLGLRIEGATVVIQGFGNVGSVTADMMQRMGSKVIAVSDVSGGYYNRRGLNIPEMIAYTKQHRSLEGYQAEGIERVSNNELLEIECDILAPCALENQITEENAGRIRCKLLVEGANGPTTPEADDILFEKGIFVVPDILANAGGVTVSYFEWVQGLQEFFWTEEEINNKLERIMQHSFESVLAQTLKHKVSMRMGGYMVAVARVAEATQIRGIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C6</accession>
    <name>A9B0C6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2597"/>
    <dbReference type="EnsemblBacteria" id="ABX05235">
        <property type="protein sequence ID" value="ABX05235"/>
        <property type="gene ID" value="Haur_2597"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2597"/>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045518_1_0_0"/>
    <dbReference type="OMA" id="AGETTWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2625-MON"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="30230" checksum="8974C2473444B5DD" modified="2008-01-15" version="1">MRVLILGASGQLGTELAKTFADHHLLMPSHQELDLSQATARAAINQLTPDLVLLPAAFTNVDGCALDPARAFRENTLGPKYAALACRDRDIPLVYVSTNEVFSGSSQQAYSEYDQPAPINAYGRSKWGGEQAVLHHAPNVFITRVAWLFGGQRNFVRTIARLGRERLQTGEPLRVVTDEVGTPTHAAEAAWAIRQLVDSNLPGIYHVVNEGACSRHELACAVLAAAGIDLPVEPITSAEFSRPSSPPPFSALSNNAAAALGIRLRRWQAAVIAAVAAIDEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0D9</accession>
    <name>A9B0D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05248">
        <property type="protein sequence ID" value="ABX05248"/>
        <property type="gene ID" value="Haur_2610"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2610"/>
    <dbReference type="eggNOG" id="ENOG5032Z2P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190785_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2638-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="71" mass="7440" checksum="FF90CE19008EE5C4" modified="2008-01-15" version="1">MADLSAFLDKAFENSSFEELADAPVDALAGISKSDAEALKQALGIKTIRQLAEHKVILIAQAIAGLATAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E5</accession>
    <name>A9B0E5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conserved repeat domain</fullName>
            <ecNumber evidence="8">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2616</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.1.74" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2616"/>
    <dbReference type="EnsemblBacteria" id="ABX05254">
        <property type="protein sequence ID" value="ABX05254"/>
        <property type="gene ID" value="Haur_2616"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2616"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003205_0_0_0"/>
    <dbReference type="OMA" id="YSDQQFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2644-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PTHR10795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732298" evidence="5">
        <location>
            <begin position="25"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="209"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="7">
        <location>
            <begin position="475"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1406" mass="145455" checksum="54BF7A6629AD7E9E" modified="2008-01-15" version="1">MKHRYTRLATVLALLTMLAGNLSANNVTRAAEPLKPVVETATDSVQVNQASANRSSKPTIAPLYGDFPKSGKVKVIVQFHEAPLATYAGEVKGLKATANAQTGRAKLDVKAAESQAYLKHLEAQHASFLKDVQAKSNQIKQIADYQVALNGMFLDVDVSAITVLRNHPDVASVEVAKVEKLDTDSSNQFIGTPSFWQNLGGGSTGTNAGEGIVIGVIDSGIYNPSSTLTTTGIHPSLRDPSPVGGDYSAWPGGYKGVCAPSNPQAQDGSFGACNDKLIGAWWYNGGGIAFPGEVDSPMDEDGHGSHTATTAGGNGGTASPFGTVSGVAPRARIIAYKVCWEEDPAISDDGGCNGGDSVDAIDQALIDGVDVLNFSISGGNSPWTDAVEIAFRNANAAGVIVSASAGNAGTVGSVAHNSPWLITVAASTQAREFKGYVSNLSGGTGTAPSPLVGASLYPGSVTGQIKLAPVQAGESVAPSLCQQPYAPGTFNATDIVICRRGVNARVLKYANVFAGGAGGGIIVNAADNQGIVADYCAKVCIHLEKNATLESVAGEALVTYVQSGTVNGKADGGVKVMGAGDKMAGFSSMGPSPIKNVLKPDVTLIGVDVNAGHTAFVWDDGFADGELFQVIGGTSMSSPHNAGVTALMRQKYPTWTPFEIKSALMTTAKTSVVKPDGVTAADPFNMGAGRVDLTKVFSAGLVLDETIPNFINANPSAGGNPATLNIASAANESCPVECTWTRTVKNTLNVPATWNVSGSTSPVTVTATPASFTIPAGGTQVITIKANVAGQPINGVWKFGEFRLTEAANRAPAVHFPIAVKASAGGVPESVSATTRRDTGMVTAGGFSALNVTNLTIREFGLTKGVRATEVITGDTTNGNPYDSLTNGVFYRALQVPTGASKFVAKITDTASEDIDLFVVRDANGDGIPQAGEQVAESATSSAYETVTINNPTAGNYIVVVQNWQASPAAPDSTTVDIYYVPGSNLGNWDVVGPANVSGSEPFSVDIHWDEPALEAGDVWFGEFDLGTSPASPGSIGRTAFTLEVLEAEVSVDVSDTMVDVGEYVTYTVNLSNYSAMNDTFYVTSTLPVGLEVDVSSLPAGASYNASTRTVTWSGLVNGAETGYTFSDSRDGGVAFDNFDVSADANAIAICAAASTTCDETAPNFTLGTYLVRAYDVNYGAVRPWSNGLIQFDPTLPSGNTNYVAQDMPNSATPNGVYAGLWTDLDLDGSSATDTGGGEYYILIVDGVNPNDPTVPYVAVEYEDAQQYDDPTSNLNFTNYARADGIESEFCTVYGSLTGNLTTFADGAAVGIENLTGTVGNTYYYSGDSSTAANLPTAGATICTSLGAGAPGLRSFSYRARATQAGVLTNNLEYSSAADSNTSTEAVAIEAVQAVFKIFMPLVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I7</accession>
    <name>A9B0I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4574"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07205">
        <property type="protein sequence ID" value="ABX07205"/>
        <property type="gene ID" value="Haur_4574"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4574"/>
    <dbReference type="eggNOG" id="COG3940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408696_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4629-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732300" evidence="1">
        <location>
            <begin position="34"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="393"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="573"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="672" mass="74015" checksum="7BD83C38E7F3CE63" modified="2008-01-15" version="1">MIGFNHRHWRWGLVLSCLSSLLVGAMLTQPTRAAEPVAVNAEGYTTRSYGSVTFEGINYAVQSNVANEYVPSTTHSYSDLGSYYLVNSDYSLPNVPNITSGVLWSTGNKNRGWAINSEYDIRALVQANGGLYAPYQTMPGYQLGPWNASTPCCGWTLQRNTTGFYIQADGKVRVPKTPAAAQQTWDANQSLTAINTTNDIVAVTDVMFPGDEDYYAGNTYLPRSAGVLTAKYKHYDNRNTHIYWGLKGQHVRDVEDWEADAPGGSKRKIYTGGFKIDESDNGQVWAGISHGNEFVDLNLQPSVTAQQLYKVELWIQRPTGMEYWGGLSYQQGADGKWRAFGDGSHVTNWGNGTFGLVATAYRNRNERLLLVYRALPGGDNPPTPTPPPPPPTNAASFNLINRSSGLCLDVAGANAADGTKVQQWTCNNATAQQWELRLAESGYYQLVSKATGKCLDLAAWSTTDGGIAHQWSCGNNQSNQQWNFQTVSDGWLRIANRNSSKYLSIVYGSVDAGAATHQWPWLGNPDQQWRIQPVGTLQIANKNSNKCIDVANNNSADGTNILQWPCYAGLAQQWQFQHSDNGYYKLRHPSSGKMLSVSGDSNADGANIHLWTAVSNPSQQWRLELLDDGFMRFVNRATGKVVDVAGGSSADNANIQQWTWNSSNAQRFKLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L6</accession>
    <name>A9B0L6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHRD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4603"/>
    <dbReference type="EnsemblBacteria" id="ABX07234">
        <property type="protein sequence ID" value="ABX07234"/>
        <property type="gene ID" value="Haur_4603"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4603"/>
    <dbReference type="eggNOG" id="ENOG5032RH1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174409_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4658-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07452">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734464" description="CHRD domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="3">
        <location>
            <begin position="101"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27166" checksum="DDEC193366744355" modified="2008-01-15" version="1">MIKQAMARGIAGLALIGLLAACQSAESTQPSATTAPAAAHTQMAHASNTTASQPANNPALDTALDPSRGQEIGYVYEAFLSPHQEPGEEEDAPAFTPDELLSSAPSQPRANRTSRGHGFLRITKDLSKAYVDVKLENVKPEDVVMFHIHCGKPDILGPILIDFAFSGNIQENLADGTFSVELTNTDIEKESEAGSGVLGLFTAGCPIVPGLPDEVQTISGMQHIAEQSELYFNLHTKGQTFYGDIRGKLQPVKNP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-10-14" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N2</accession>
    <name>RIMM_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rimM</name>
        <name type="ordered locus">Haur_4619</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B0N2"/>
    <dbReference type="SMR" id="A9B0N2"/>
    <dbReference type="STRING" id="316274.Haur_4619"/>
    <dbReference type="EnsemblBacteria" id="ABX07250">
        <property type="protein sequence ID" value="ABX07250"/>
        <property type="gene ID" value="Haur_4619"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4619"/>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_3_2_0"/>
    <dbReference type="OMA" id="DEFYHAD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_0000351765" description="Ribosome maturation factor RimM">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="PRC barrel" evidence="1">
        <location>
            <begin position="98"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <sequence length="174" mass="18982" checksum="CE9E4E385919677C" modified="2008-01-15" version="1">MTAPNQDDFLLVGRISAAFGVRGELKISMISSHPEHIQKLKQLFVGDLSKPYTIGRLHQHKGSLYLLRLNEVDTRDAAEAMQGLEAYIHRSDAAPLANDEYFLHDLVGLQVQTEAGEDIGRAVEIIETGANDVLVVRKLGQADILVPMVRTVVRSIDIAGGTITVTSLADIVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U3</accession>
    <name>A9B0U3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1165"/>
    <dbReference type="EnsemblBacteria" id="ABX03813">
        <property type="protein sequence ID" value="ABX03813"/>
        <property type="gene ID" value="Haur_1165"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1165"/>
    <dbReference type="eggNOG" id="ENOG5031RHM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1685284_0_0_0"/>
    <dbReference type="OMA" id="ADIWMRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1187-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17287" checksum="E2A440B2966C9F81" modified="2008-01-15" version="1">MLLAVDLGIRTGFACYNRAGQLLWYRSHNYGSLPRLRRGSSGQLNEVSDLSVLVLEGGGPIADVWEREATRRDLQLIRTSAEVWRASLLYAREQRTGEQAKAVADELARRVIEWSDAPRPTSLRHDAAEAILLGLWAVVELGWLAAIPPEVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0W5</accession>
    <name>A9B0W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1187"/>
    <dbReference type="EnsemblBacteria" id="ABX03835">
        <property type="protein sequence ID" value="ABX03835"/>
        <property type="gene ID" value="Haur_1187"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1187"/>
    <dbReference type="HOGENOM" id="CLU_1872603_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1209-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735164" evidence="1">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="15289" checksum="78399690760D1BC9" modified="2008-01-15" version="1">MRFKQLLIGCLLLTLTACGGDDTAPVNQVKAFVAATEERNVDRMIALMVPDMRRDAGWQLRQVMPRIQSIDYQDDQYTLEKIDDGRAYVQVNGILVAQMTDGQTVEYPANQLVELIEQDDGTWLVANSGFEIPNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y6</accession>
    <name>A9B0Y6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4367 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2626"/>
    <dbReference type="EnsemblBacteria" id="ABX05264">
        <property type="protein sequence ID" value="ABX05264"/>
        <property type="gene ID" value="Haur_2626"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2626"/>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_856866_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2654-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025377">
        <property type="entry name" value="DUF4367"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14285">
        <property type="entry name" value="DUF4367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4367" evidence="2">
        <location>
            <begin position="335"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="41218" checksum="345D6F36E2F82783" modified="2008-01-15" version="1">MLVLTMVLAGCGQEDITAENIVTKIREGQANTNNVHAIMRVDYTSDQATGFIKAEVWSSKTGNKDAEGNEIKAFRAKILDANDAKMVGAEVVTDGTQGWFYDPAENKAYVGTAAELSESQMGQGQQDQEQGQGGRGRMDQTEMLGQLQGVVEKGLDALTITILGEEEVAGFNTYKVSIAPKSDAQQQLPIDLLVDINVWLEDTNWMPVKFVLDAKDMGNVSFAAETLEVNKGIDMAIFSAQPPANAEIVKIADMIKEMEQAAPATDLTLDEAKAQAGFELLAPGETLGTTLSDVQLLTLAKATTVIQTYAGADVEWTLVQAKGDDPDAKIQRGGTEVTVRGVQGTLIEGRGNVGVVLTWQEGDVTFVITGNIDGEQATKIAESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z4</accession>
    <name>A9B0Z4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ordered locus">Haur_2634</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2634"/>
    <dbReference type="EnsemblBacteria" id="ABX05272">
        <property type="protein sequence ID" value="ABX05272"/>
        <property type="gene ID" value="Haur_2634"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2634"/>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_0_0_0"/>
    <dbReference type="OMA" id="YVMMDYD"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="51"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="232"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX05272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="36039" checksum="063079E078990B8D" modified="2008-01-15" version="1">MLRFAVPSKGALADDTFRFFESCGLKVSRPNPRRYTASIKALPEVEVLLHRAPDIVEKVADGSIDLGVSGYDLVEELGGESDDLVVVYKDLGFGYCDLVLAVPDHWIDVTSWRDVADLAAEYARAGRQLRIATKFPNLVRQWCHQQGINVFALIDSQGATEAAPSLGYADIIADLTATGTTLRDNHLKMIQGGTILQAQAALIANRRSLRESSQKQRVVQSILELIEARHRAKTYVSLIANVPGSDVADVGARVVAHAALAGLQGPTVSPVWSRDGGEGWYAVSLVVDSANILPAIDHLRSIGSTGITVLPVHYVFAERSQSFAALSELMHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B125</accession>
    <name>A9B125_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VanW family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2665"/>
    <dbReference type="EnsemblBacteria" id="ABX05303">
        <property type="protein sequence ID" value="ABX05303"/>
        <property type="gene ID" value="Haur_2665"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2665"/>
    <dbReference type="eggNOG" id="COG2720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011572_0_1_0"/>
    <dbReference type="OMA" id="FYIERYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2695-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022029">
        <property type="entry name" value="PG-bd_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007391">
        <property type="entry name" value="Vancomycin_resist_VanW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12229">
        <property type="entry name" value="PG_binding_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04294">
        <property type="entry name" value="VanW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_4" evidence="3">
        <location>
            <begin position="126"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_4" evidence="3">
        <location>
            <begin position="252"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="686" mass="75267" checksum="81764CAC077BCAA9" modified="2008-01-15" version="1">MADEFYQKYGPIERRRQNGDVQQFDATAPLADDLPVRSAAPPKRKRSRLRTFMWGAGITLGLVGLLFGIGLWYLNRTFEGRIYPNVAIQGIDMSQKTPEEAKALLAEQYADLLKRPVGLSFNGQTWEPTADQAGISLSIEQSVDEAYSLGRGGNIINTLQAVSGIWQNGYDIPLAVTVDQAQLSEYLTTATNDLITAPVNANLIVAGNTATMTPAREGRLILIDETAQDILTQLQTLSPAQVVLRTEMVMPTVLDDGVFEAKQTIDAVLQSPLTLIAGDLQWELSTDDLRALIRLDTHTDANGKTKMVASLNDQMIRQRVATFADEIGRGSVNPRVAWDGGALTIVREGRTGLRLDEEASARRIIEQATIGETRTIELVIREVQPDVTAENIHSLGIVEAVGVGKSSYKGSASYRVTNIKAGSRLLDGILIKPGEEFSFNNAVGSIDEANGFVKGYAIVGNRTQEEWGGGICQDSTTLFRAAFHAGLPITERHTHSFRISWYEVYEPYGMDAAIFTGALDFRFVNDTGKWLLLNTYVDDSTATVTYALYGTAPQREVILDGPYVTKEYPKPTEPTYIADPKEPVGVFHQTDTARDGMDIIVYRIIRQDGQVILREPFNTHFKPWPDIYVHNPATPLPPKGCKPTDPCANPATPTPEPQPPQQPEPTPEPQPEPTPGGEIVVPTPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B166</accession>
    <name>A9B166_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2706"/>
    <dbReference type="EnsemblBacteria" id="ABX05344">
        <property type="protein sequence ID" value="ABX05344"/>
        <property type="gene ID" value="Haur_2706"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2706"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064910_0_0_0"/>
    <dbReference type="OMA" id="IMFLDIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2737-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="28089" checksum="6F9609F9D4CA03F5" modified="2008-01-15" version="1">MEWLSDPQTWVSLLTLTMLEIVLGIDNIVFISILSGKLPQAQQAKARQTGLALALITRILLLLSLSWVMSLTKPLFTVIGQEISGRDLILLVGGLFLLGKATFEIHERLEGTEHHEQNVKAKSFNSVIVQILILDIVFSLDSVITAVGMVDHIEIMIAAVVISVGVMLLSAGKISDFVNSHPTVKMLALSFLLLIGMSLVAEGLDQHIPKGYIYFAMGFSVLVEMLNLRVKKVTQKPVELRQPSYLQEAVEESTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K9</accession>
    <name>A9B1K9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1246"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03894">
        <property type="protein sequence ID" value="ABX03894"/>
        <property type="gene ID" value="Haur_1246"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1246"/>
    <dbReference type="eggNOG" id="COG1501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_10_0_0"/>
    <dbReference type="OMA" id="FEIATEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1268-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gal_mutarotas_2" evidence="3">
        <location>
            <begin position="158"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="774" mass="86545" checksum="71C51DD07899FE4A" modified="2008-01-15" version="1">MKFTDGYWMMREGVNALFASQAYDGQINDTTLTVYAPGKRINHRGDTLNLGTITARFSSPMPDVVRVKLTHFEGQRSLGPNFAIAESANESVSTSEDEQEFRLTSGKLSVQIPKTGDWSINFWAENRRITSSGRKGIGYISMADAGEFMHEQLSLGVGEQVYGLGERFTAFVKNGQSVDVWNQDGGTGSEQAYKNVPFYLTNRGYGVFVNQPENVAFEIASEKVSRVQFSVPGQSLEYFVIYGPTPKEILEKLTALTGRPALPPAWSFGLWLTTSFTTSYDEQTVTSFIQGMADRDLPLHVFHFDCFWMREFHWCDLEWDSRTFPDPEGMLKRLKDRGLKICVWINPYIAQRSAMFREGMEHGYLVKKPNGDVWQSDMWQSGMGLVDFTNPAACAWYAAKLKGLLDMGVDCFKTDFGERIPTDVAYFDGSDPQRMHNYYTHLYNKTVFDLLKTERGENDAVVFARSATAGGQQFPVHWGGDCESTFESMAESLRGGLSLGLSGFGFWSHDIGGFEGMPPVEIYKRWIAFGMLSSHSRLHGNHTYRVPWIYDEEAVDVLRYFTKLKSRLMPYLYGAAVTASTSGIPVMRAMLLEFPNDPTCDFLDRQYMLGDSLLVAPVFAYDNTVTYYVPAGRWTHITTGAVVEGPRWVTETHDMLSLPLLARPNSLIAIGNNSERPDYDYSSGVTLNLYQLGDGQAAYTMVPATNGDIAASWSARRDGDTIRIVQEGQANDWQVVLVGVQQVASADGALVEQHPLGVQLTALDQATKLVVKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L6</accession>
    <name>A9B1L6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1253"/>
    <dbReference type="TCDB" id="9.B.8.2.8">
        <property type="family name" value="the duf2157 (duf2157) family"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03901">
        <property type="protein sequence ID" value="ABX03901"/>
        <property type="gene ID" value="Haur_1253"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1253"/>
    <dbReference type="eggNOG" id="COG4984">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050363_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1275-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018677">
        <property type="entry name" value="DUF2157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09925">
        <property type="entry name" value="DUF2157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2157" evidence="2">
        <location>
            <begin position="19"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="37735" checksum="4B3A44B5D894562B" modified="2008-01-15" version="1">MIELPDPLDQAPTRDILHHYVDEGIFNRPTMKRALQLSGFTPTAQAWVRFFNLILLVLGAGLAVCGVYFFFAFNWASMHRFAKLGLVEGALLISIVAALWYGLERIQGKILLMVSACLVGALMALFGQIYQTGADAYTLFLNWALVITGLAIAGNFAPLWLLWWGLWNLTIVLYYDQTSDFRNTNDLFVLLLFNALIFALAEGLRQRKLAWLQTNWLHRVLGLGLLWVLSLISNNFVDTVFSYGSDKPSIALFLLYSLALVMLGLMGAYHYFVTFDGLLALASLGTICFFVDCWLFEWLSYDSGATFLFGGMIILGQTVVSILWVRQRQQLLGGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q6</accession>
    <name>A9B1Q6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1293"/>
    <dbReference type="EnsemblBacteria" id="ABX03941">
        <property type="protein sequence ID" value="ABX03941"/>
        <property type="gene ID" value="Haur_1293"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1293"/>
    <dbReference type="eggNOG" id="ENOG50302XP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149392_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1315-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="16072" checksum="91DA6DB49EDA1282" modified="2008-01-15" version="1">MPKFSQISIRAALLYLVIGGSVGGILLVSKAFGVWPWIWYWRTAHIHAMLVGWLLNLIFGVAFWILPRLDANGWRGSPWLVWSASGLLHIALAVLIWASIWPWSAAIFIASGLECAAAIAMAWHCWPRLQPLIIEPILHQKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R2</accession>
    <name>A9B1R2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1299"/>
    <dbReference type="EnsemblBacteria" id="ABX03947">
        <property type="protein sequence ID" value="ABX03947"/>
        <property type="gene ID" value="Haur_1299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1299"/>
    <dbReference type="eggNOG" id="ENOG50340UV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_653406_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1321-MON"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
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        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
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        <location>
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            <begin position="211"/>
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        </location>
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            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="46274" checksum="D86621F965BB96DA" modified="2008-01-15" version="1">MMARHSKLFWLSGLVALLLATIVHLALTAAGPQRWDAWVHLLLYGWISCSIFAVNYHTTPVFSGRNFPKPAWLELHWLVWSLGVVLASSGLVWYSQLSYRLGLGLEWLGSWLFMWNIMQLLRSPKLRPSMPSSPLQQQIDRLSTLATKTSGASLPLALSLILAREFGLIHSRWLLSAEHLLTLGWMMLMIIGVACHVLPRWSGQATRDPRWLKVGLSLHHLGLLSIVLGLGVDLPALFALGASFILVALACCVWLLIPALATPPVKQPSQLSIVQPRRIGPLTMWSIRAAVFYLAVGIGLGISFAFDRALGAQLRPIHVESNLAGFATILIYGMAYFMIPRFMGRPLGLANIANWQVFLAISAVAIIDLGWAGLVAGLAWARWLLVFGASIHGLAALLFSLSMLATIYQPVPLRRLAHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B235</accession>
    <name>A9B235_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4754"/>
    <dbReference type="EnsemblBacteria" id="ABX07385">
        <property type="protein sequence ID" value="ABX07385"/>
        <property type="gene ID" value="Haur_4754"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4754"/>
    <dbReference type="eggNOG" id="COG5621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040626_0_0_0"/>
    <dbReference type="OMA" id="AWLDHEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4812-MON"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AttH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07143">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
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        <location>
            <begin position="72"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="383" mass="42752" checksum="8DA24BBD8D285D60" modified="2008-01-15" version="1">MRIRLILTILVIVGLLGGATWWVLQPTQTQIQASISAVGMLNQASQGNYRRATEPRPFEFPADHGSHPGYRTEWWYYTGNLASADGQRFGFQLTFFRSAATDQVISRTASLATSDIYMAHFALTDVANQRFYAFERFMRGNPQLANATGDPFKVFVEDWQALGSGLEGMTMQLRAKQAPVKLDLTLQSSKIPTLQGDRGLSQKGAELGNASYYYSLTNMTTTGTLQIDGREIAVTGKTWMDHEWGTSALEDQAVGWDWFSIQLDDQREITYFNIRNADGSISPYSTGTLTLADGTTRKIERDSIKLEVLQQWQSDQGTQYPAQWRLSLPSEQLELTITPQLANQELPLTVRYWEGSVAINGSVTGFGYVELTGYGDSDRGRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C1</accession>
    <name>A9B2C1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1318"/>
    <dbReference type="EnsemblBacteria" id="ABX03966">
        <property type="protein sequence ID" value="ABX03966"/>
        <property type="gene ID" value="Haur_1318"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1318"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069129_1_2_0"/>
    <dbReference type="OMA" id="WNFWISA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1341-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="47"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="252" mass="28880" checksum="A92F1C2E700B6A40" modified="2008-01-15" version="1">MDEQRMWWEELFQIHEFATYSDVAESLTNNEVDFLEMILNLTPDMRVLDLACGNGRHLLGLARRGYHVDGVELATPLVNQLSAQITAEQLPARVIAGDMRKLDDLGMYDVVLIMNSSLGFFSDFEHQQLLNDLADHLVPQGRLVLQCINPYQISSYMQHYRRGWHQVGPGYVLRESHFSPTTGTIETAYRYIEPNGGEAVHPGERIRLYTFPEWQQQVQRAGLRLQAVFGDAVLPIVPFDETSQWQILMAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J8</accession>
    <name>A9B2J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1398"/>
    <dbReference type="EnsemblBacteria" id="ABX04043">
        <property type="protein sequence ID" value="ABX04043"/>
        <property type="gene ID" value="Haur_1398"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1398"/>
    <dbReference type="HOGENOM" id="CLU_160607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1419-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14787" checksum="5288C22210BE03DB" modified="2008-01-15" version="1">MVFFTMRQLSNKIKQHSEVEGSLRALSIKSGVSYTGLKNLRDNPDVTPDLETLVKFAKTFKLPFWRIIEMAGFDLEFSETSTIQAQRLISVMDAMPEYQSVVEHLLELDSYEVNSVLIYLETLKNHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L4</accession>
    <name>A9B2L4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trehalose 6-phosphate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="EC" id="3.1.3.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2827"/>
    <dbReference type="EnsemblBacteria" id="ABX05465">
        <property type="protein sequence ID" value="ABX05465"/>
        <property type="gene ID" value="Haur_2827"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2827"/>
    <dbReference type="eggNOG" id="COG1877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037265_0_0_0"/>
    <dbReference type="OMA" id="YGAERWD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2858-MON"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044651">
        <property type="entry name" value="OTSB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43768">
        <property type="entry name" value="PTHR43768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="27220" checksum="83AB783ECB9B186F" modified="2008-01-15" version="1">MGLITDIDGTISRIAPTPDGATVDPLCRAALSQLTEHLPLVAAVSGRAARDVQRMLQLPAMRYIGNHGLEIWGQDGGVLVPAAQPYSAAVREFVAAMQRYELPEGVVLESKGITATLHYRLATDQTAAELWLRKVLSELAAAHNLIITEGLMIFEVRPPVDWHKGSAVAWLIEDHKLEAAIFLGDDLTDVDGFRSIAAARERGCQALAIGVINPESHPSVAETADILINGVDASAEVLQWILAQRLSDSHGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P5</accession>
    <name>A9B2P5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methicillin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2858"/>
    <dbReference type="EnsemblBacteria" id="ABX05496">
        <property type="protein sequence ID" value="ABX05496"/>
        <property type="gene ID" value="Haur_2858"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2858"/>
    <dbReference type="eggNOG" id="COG2348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048411_0_0_0"/>
    <dbReference type="OMA" id="FGLIQFK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2889-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02388">
        <property type="entry name" value="FemAB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="37951" checksum="6007EE9362B031DE" modified="2008-01-15" version="1">MYVAILPQLSVSSELGQKWEALVQANPAGGVMQSLAWGQFKQQRGLNVVHFGLFAATDQLIGGMLCTIPAQSGVGSNLIAADGPILPWHDQALARQGLRLLREAAEHHASAYGAVGLRIEPRLERPASNLLRDWRRAPVDMLARETLYLDLRPSAEQLLAAMKPKGRYNIRLAARRGVTVRISHDLADIPLFYRLMDEAGERDDFYVEPIDHFNDLLATLAPLGYAHLLFAEYAGQTLGTLLLITYGQRAVYQYGGISNQLREQMAGYALQWAAIQQAQRLGCTSYDFYGFEPTGDPHHPFAGFSRFKRAFGGQAIALIGAYDYYFTEQLADVIIRAVRELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W1</accession>
    <name>A9B2W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3388"/>
    <dbReference type="EnsemblBacteria" id="ABX06024">
        <property type="protein sequence ID" value="ABX06024"/>
        <property type="gene ID" value="Haur_3388"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3388"/>
    <dbReference type="eggNOG" id="ENOG5033ZDF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1072384_0_0_0"/>
    <dbReference type="OMA" id="FSNITAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3425-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="28210" checksum="54364D23287A6FA5" modified="2008-01-15" version="1">MAKLRQIWAWTRFIWSEYQRTGRFLVELGALIIFAYVFLRKPNVDAHLTATQFFGMTAIFVLCQTIFTTTMMAGLGNRPQGYVVLARSLGRKGYLVGLFLVAFLISLVNLILCTIIVTIINKPVLWDAVIWGAGALPLILDIALVTALVLLLSSLVLSQGWRLSILAVIALASLSTSDIFTNTFDPNGSLGKILAAIRTIVGIPLTPLFAGFELAVTRQAYESNLNQALAILGGQAALLIAVSAFGFFAFERRDIILGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y1</accession>
    <name>A9B2Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA containing CoxE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3408"/>
    <dbReference type="EnsemblBacteria" id="ABX06044">
        <property type="protein sequence ID" value="ABX06044"/>
        <property type="gene ID" value="Haur_3408"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3408"/>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_568468_0_0_0"/>
    <dbReference type="OMA" id="VDWLDDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3445-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="296"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="460" mass="52182" checksum="E09214296405BE99" modified="2008-01-15" version="1">MNQSELLNRRQVLYWRMLSTMFGYDQQGENFDSMSHEIAQDLALPESILHPTLSLEQLFQRYPELEPEFNLTELDDRQDPTTLRRSLIISKLLLNVFGPQTQKRSISAAEYAQWLKDVAHLERCLGFQPGALRQSQPGQGQASQPGGLQGGQGVGSGFNLSEEELRQVIQGLEKDLIKRMALREVLQDNRLAAQLTPSMAVVEQLLRDKSHLSGNALINAKRLIKQYVDELADVLRLQVMQAVSAKIDRSVPPKRVFRNLDLKRTIWRNLTNWNSNEGRLYVDRLYYRQTAKKRTPMRMIVVVDQSGSMVDAMVQCTILASIFAGLPHVDMHLIAFDTRMLDLTPWVHDPFEVLLRTQLGGGTSINEALLFASEKIQEPRKTAVVLITDFYEGGSDQVLLDTIKAMIESGVHFIPVGAVTSSGYFSVNDWFRTKLKEMGRPIFAGSPRKLIEQIKQFITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y5</accession>
    <name>A9B2Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3412"/>
    <dbReference type="EnsemblBacteria" id="ABX06048">
        <property type="protein sequence ID" value="ABX06048"/>
        <property type="gene ID" value="Haur_3412"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3412"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008973_1_0_0"/>
    <dbReference type="OMA" id="DHAHIFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3449-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="172"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="318" mass="36115" checksum="CB7E583FC1F3DCAA" modified="2008-01-15" version="1">MYYTIRHVTRFRYSNPISESMMEVRKQPRTEGDQRCLSFDITTKPKSKVLVYYDSQGNTVHHFGIPRAHTQLEIITQAYVENRIQAPADDLMLDLNTWQGLEDHALNGHDWDYLNSSQFVHSTDLLQAFANEIGLSKQLDPLTLIRQITQAIYDKFEYVPQSTRADSPIDEALATRRGVCQDYTHIMLSLLRWLQIPARYVSGYLFHRTDDSVRSAADASHAWVEAWLPSLGWVGFDPTNNVVVADRHIRVALGRDYADVPPTHGIFKGETQSTLEVAVQVCLADEPLQADQPSKLEGWSVVEGGDVAAVLQQMQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B306</accession>
    <name>A9B306_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4839</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4839"/>
    <dbReference type="EnsemblBacteria" id="ABX07469">
        <property type="protein sequence ID" value="ABX07469"/>
        <property type="gene ID" value="Haur_4839"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4839"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_2_1_0"/>
    <dbReference type="OMA" id="GWYKGRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4898-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="4">
        <location>
            <begin position="99"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="29618" checksum="241CECCE05E78ACC" modified="2008-01-15" version="1">MDNDDQPVGRILSRREVLRLFGLAGSAAVIAGCSSEVAPTATTVAQASAPTATATSAATNTIAEAATATAAATSTAEATATSEAVAALPSCIVRPELTEGPYFVDEKLERSDIRSDPSNNAVSAGTQLDINVVVSQIGAGTCTALAGVIVDLWHCDADGVYSDATDRSFNTVGQKFLRGFQRTDASGLAKFTTIYPGWYQGRAVHIHFKIRTDEGYEFTSQFFFDESLTDVVHAQAPYVAKGVRTLLNDGDGIYQQSGGQTILTVTPSAQGYSATFEIGLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B319</accession>
    <name>A9B319_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4852"/>
    <dbReference type="EnsemblBacteria" id="ABX07482">
        <property type="protein sequence ID" value="ABX07482"/>
        <property type="gene ID" value="Haur_4852"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4852"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014916_0_0_0"/>
    <dbReference type="OMA" id="VPLIAHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4912-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="648"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="884" mass="98296" checksum="DECACD08A2538835" modified="2008-01-15" version="1">MQKTSTPQLRQFLIDNAEQVIARWVHRLGTAVPKNGVHFPSVHVRRLYELLLTLPDEQTDLELALVELGIDWHAFELTTLIQLSFQLRPAIVDVLQTHKLTRWQSSNELDQLVERCTILLTNHHNTTVQAELREQVAQAEYLLDHQAQMASESDYFALQMSTLYELSQAMSASLDREILEDIGPRILSAFTVERCAIVLRIDDDTWMIEHAWGDDWAKLTGQPLDPENLPAALKVATAQGMVQLQPMVEPNSTSWMVDNQGALFVPLRQENNMLGCLVAQGSTLIERIDDVMMNLWRTVANQIVVTLQNIRLYSTVQQLNADLERKVAERTAELSEERDRLEAIADIARDISTLEIDVLLNRILQALANLTGVQHGSVMLIDAATGLLVDRATLAGISHTLGSRRFQIGEGLVGWIAQHRQPALVNDVTNDDRWVQVDAFGQEVGKNTGSLVGMPLIAGDDIVGVLMLSHPKSHFFNQSHMRLLKAIAGEIAIAIYNAQLYEYLAERTIKLSTMLRHQEEVSSQNNAILQSLNDAVIVFNLDRNIILANAAAESILDRPLDELVTQSFDELLESLNIKLPGDPLGAVLNNPDATQTQGIIIKRATQSISVTLVPVMTERGELLGACLIGRDITREVESDRLKTEFIGTVSHELRTPMTSIKGYTQLLAMGSLGEVNSTQKEFLNTIAHNSERMIAIINDLLDITKIETGSVELQMARLMVADVMSSVVGNARAEITQRQQEFSLSLAPNLPTIWSDMERIRQVASNVLSNAIKYTPNGGKISVKAFEINFNDIPNKQREGLQVGRRYIALAVQDSGVGIDPSEHEKVFDRFYRTENPLKIEAGGTGLGLSLVRPLIQLMGGRIWLESAVNQGTTFTFIMPVAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F8</accession>
    <name>A9B3F8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1477"/>
    <dbReference type="EnsemblBacteria" id="ABX04121">
        <property type="protein sequence ID" value="ABX04121"/>
        <property type="gene ID" value="Haur_1477"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1477"/>
    <dbReference type="eggNOG" id="COG1030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024619_1_0_0"/>
    <dbReference type="OMA" id="QMDTPGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1499-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735221" description="NfeD domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="4">
        <location>
            <begin position="352"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="436" mass="45586" checksum="3D74B8B333E92E55" modified="2008-01-15" version="1">MRQLRILALIVWLSLVTLPSLSYAATDDAMCVASVSGIINPAVADYLQRSVIQAEQQACQGLVIKLNTPGGLTTSTWQIGETVLNAKLPVIVYVTPQGANAGSAGVFITYAAHIAAMSPNTNIGAAHPVDGSGVDMEGDLRDKITNDAVARITTWAESNDRDAEWAEQAVRQSVSIGSNEALELGVINLIAQDDADLLRQLDGREVTLANGNQVTLQTQTSAFQPIEMTWLERLLHFLGDPTIATMLISLGSLGIYFEAANPGLGVGGFLGVIAICLGLYGLSVLPLNTVGVVLLILAFVLFGIDIFATAHGALTVGGLASFVIGALLLVDPAEAPGIIVSRALITGLGLGLASVIGLSIWIIRRSKRVGRGASGDRLVGTIAKVRSSVAPEGTVFVEGALWQARSDDVLTVGDQAEIVGLDGLTLIVRRVAHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P3</accession>
    <name>A9B3P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2977"/>
    <dbReference type="EnsemblBacteria" id="ABX05615">
        <property type="protein sequence ID" value="ABX05615"/>
        <property type="gene ID" value="Haur_2977"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2977"/>
    <dbReference type="HOGENOM" id="CLU_813231_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3009-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="37859" checksum="027C3DD83557817F" modified="2008-01-15" version="1">MNSLAAIPHLHDLPQVVETVKRRQLSGRLTWIDHIDRVHLFFVDGILRHGQVDPHGQIGEDAVDWLLTRRSGHFEWNAADNLFKPAHSINADMVANFDRLLTIMVEGEILNRPPEHDFALEFFGLSAAPIPKAALIPQPVRRSLVLPPGEHDPNSSKQLQSLPLGKQLEYLQTRRFSGYVYYQPGAQSTGFVMGIVMFSEGHLRGVHAQDLSNDQWYSANQALQHLANAHSQPELYQTPARLIDACAAIVGADPSRPVAIAASKTILQQVVNDVHKRSATGAVQLCVPDKPTLYVPFYQGQVIGILEHESGNSRLKPMPNNHPLPFGVPNITLRVLEQATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3V4</accession>
    <name>A9B3V4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3454"/>
    <dbReference type="EnsemblBacteria" id="ABX06090">
        <property type="protein sequence ID" value="ABX06090"/>
        <property type="gene ID" value="Haur_3454"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3454"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_0"/>
    <dbReference type="OMA" id="LPAPYCR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3491-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="32339" checksum="3E1CB3DA81BEA6A4" modified="2008-01-15" version="1">MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDAGKLLLPYARRVLAELQAARHALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGIQLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMSEPLVVAVGLQHRFAQRQSIAANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQLAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B420</accession>
    <name>A9B420_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="6" type="ordered locus">Haur_4923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4923"/>
    <dbReference type="EnsemblBacteria" id="ABX07553">
        <property type="protein sequence ID" value="ABX07553"/>
        <property type="gene ID" value="Haur_4923"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4923"/>
    <dbReference type="eggNOG" id="COG0186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_1_2_0"/>
    <dbReference type="OMA" id="HPMYGKF"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12918" checksum="9169EBF8497B74C4" modified="2008-01-15" version="1">MNEHLATTDSRKQKVGRVVSNKMNKTVVVAVDYLRPHPLYRKTVRQTSKFYAHDENNECHVGDTVVIEETRPLSKLKRWRVVEIATKNRREGLNVLRQDVVTVEGETEEASS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-26" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B478</accession>
    <name>NUOB2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit B 2</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit B 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit B 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoB2</name>
        <name type="ordered locus">Haur_4981</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B478"/>
    <dbReference type="SMR" id="A9B478"/>
    <dbReference type="STRING" id="316274.Haur_4981"/>
    <dbReference type="EnsemblBacteria" id="ABX07611">
        <property type="protein sequence ID" value="ABX07611"/>
        <property type="gene ID" value="Haur_4981"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4981"/>
    <dbReference type="eggNOG" id="COG0377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_3_0_0"/>
    <dbReference type="OMA" id="IEMIATT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000376255" description="NADH-quinone oxidoreductase subunit B 2">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <sequence length="250" mass="27009" checksum="50DC4FC37E353458" modified="2008-01-15" version="1">MSDLQTQMDLEQQGVLFTTINKLYNWGRRSSVWPMQFGLACCAIEMIAAAASRYDISRFGSELFRASPRQADVMIVAGTVTKKMVPQVVRLFNQMPEPRYVISMGACATSGGPFRDGYNVVRGVDLYVPVDVYIPGCPPRPEALLHALMTLQAQIDVQSLQQVRWYGDDEGVVNEFPVPIFGAEGLEVPGIPGTADPVGGTPKMPPFVSPALGGKGERDASIKALEGNQPKPMLRAGTVTIEEVAHGIAG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B496</accession>
    <name>DNAA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaA</name>
        <name type="ordered locus">Haur_0001</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B496"/>
    <dbReference type="SMR" id="A9B496"/>
    <dbReference type="STRING" id="316274.Haur_0001"/>
    <dbReference type="PRIDE" id="A9B496"/>
    <dbReference type="EnsemblBacteria" id="ABX02653">
        <property type="protein sequence ID" value="ABX02653"/>
        <property type="gene ID" value="Haur_0001"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0001"/>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026910_3_1_0"/>
    <dbReference type="OMA" id="FPAFKIV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000121988" description="Chromosomal replication initiator protein DnaA">
        <location>
            <begin position="1"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="172"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <sequence length="472" mass="52821" checksum="1257B0E47CD4EFC5" modified="2008-01-15" version="1">MDTKQIWFTTLGTLQNQILRYDYDTWLKTTALVSVANDLAVIGAPNVTTKQVIEDRFMSVLRRALGEVLGYQVNVRVIISSATPAPSEPVAVTPSEPSPTTEVAEPSFASFNQAAPMLNQLPLGDPNRSSVLNPRYTFSSFIVGTSNRLAHAACMAVAEHPAQAYNPLFLYGGVGLGKTHLLQAIGNYALDRNPEVNVLYVSSEKFTNDLINAIRRQQTEEFRIRYRNIDILLIDDIQFIAGKEGTQEEFFHTFNTLHGAGKQIVLSSDRPPKAILTLEERLRSRFEWGLIVDVQNPDLETRTAILRAKGETLQVPVSSEVIDFLAQRIQSNIRELEGCLNRVIAYANLNRTPVTVEVASAALADLLDTSRRKRVTADDIFREVSQHYGIDQRAIRGRGRSRNVVLPRQVVMYLLREETDASLVEIGELLGGRDHTTVMHGYNKITDDLTSDARLRNDITSLRQRLYGENAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J5</accession>
    <name>A9B4J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04160">
        <property type="protein sequence ID" value="ABX04160"/>
        <property type="gene ID" value="Haur_1516"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1516"/>
    <dbReference type="HOGENOM" id="CLU_1292918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1540-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="24435" checksum="D315CA6779A53FCB" modified="2008-01-15" version="1">MQTPSKLAYIPLFNLVKWWQALNMLVVGSDRLGAAIVEEYRATATHDFLRYLQHSGLISELRHSCADLRFFIGQQLPTGLEKPNPDYHDLLELLSTELGYFWNEHPPQAPRPNHATLPLYKLWQWWHTLTMIVAAFEQLPDQTEASDQTLNEQGLIDYLTQTGLFLACGQIRYDLNIVLAQHDLSFSNPYELDHAGLFGQIAVRLGYAWQAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B541</accession>
    <name>A9B541_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3542"/>
    <dbReference type="EnsemblBacteria" id="ABX06178">
        <property type="protein sequence ID" value="ABX06178"/>
        <property type="gene ID" value="Haur_3542"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3542"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_399486_0_0_0"/>
    <dbReference type="OMA" id="FEWRPEN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3579-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735458" evidence="7">
        <location>
            <begin position="28"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="147"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="413"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="638" mass="68768" checksum="6F17179B16FC3BB2" modified="2008-01-15" version="1">MQRTVRMGLLLLLAFGLMPLIQRPAQAATLDDQIIADEILVTFNDGYRVSANGAFFEGSKALKNGLGIGPLLSTQMLDGAGQVAMLKLPAGANGDAKIAQLLKNPAVRYAEYNAVREILVDPNDEYYSEQWGLPKIGANAAWDMTQGNGLVIAIIDTGVSPTHPDLAGHVLPGYNALQNNSNSQDDQGHGTAMAGIAAALTNNGQGVAGVCWNCQILPVKVLNSRGQGTAADIVEGMYWAADNGARIISMSLGGPRGTQAEQDAVNYIYSKNIPLFASSGNSGDEGNPRMYPAAFDHVIAVGATTTQDRVASFSSYGDYVDIAAPGVNIVTTGWDGGDTYEMGSGTSPACPFVAATAALALSVWPELTVDQIEKLITGSAVDILTPGKDVYSGFGRLDTYKTVQNAVLRTIPGEPQPQPPAPPAPQPPTPEPQPGNPAFVPVGAPPLPAPVGEVYFPETGHNLRGEFKNYWDRNGGLAVFGFPISEEFTEQTPEGSFTVQYFERQRFEFHPEKAAPYNVLLGRLGDAVLRDRGDDWANFPKTGPENGCLYFDQTQHKICGEFRKYWETNGLNDPALNKYDRSLQLFGLPLSEPMTETNRDGATVTTQWFERGRFEYHEGQGVLLGLLAKEYANNRSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B556</accession>
    <name>A9B556_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3557"/>
    <dbReference type="EnsemblBacteria" id="ABX06193">
        <property type="protein sequence ID" value="ABX06193"/>
        <property type="gene ID" value="Haur_3557"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3557"/>
    <dbReference type="eggNOG" id="COG5316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025153_0_0_0"/>
    <dbReference type="OMA" id="WKTSYRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3594-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="637" mass="72013" checksum="4583D77A9A812E41" modified="2008-01-15" version="1">MTELPLRRLILYKHGVGYFERRGQFEGTKLALAFSREAMDDVLKSLVVLEKGEGHVKGIDYERPESWSSRRIELGAGRPLRDLLTELRGRRIRLALRDEAAAEGLIVGIDEPPPEEPISQSLVTIYRSDVRQITLHRLNDIRGVQLLDSAADEVLWSLRANSDKQDSRTATIQLDEGKHDLLVAYLAPAPSWRVSYRIIVDNIETELPDVLLQGWGLFDNVLDEDLEDVRISLVAGRPVSFRYPLYEPQQPERPLIEDTIRPAAPPAYTLAAPAPASAPRPKMMRAMAMREEAFAGADLDSLSMDEMASIAPVAEGAAQGALFRYDVREPVSVGRGRSALVPLLNLRTACRRELVYRGAAGETHPMVTVRFENSSGLTLERGPITIMESRSYGGEAVLNWTAEGAMVTIRYAQALEVSVKENQNSAHQTRRIRLGRDVLIHEVEESLTTIYTATNTAGEARVIKIEHPLRHPYELFDTVQPAEANSQLASWLLPIPARGEAALRVRERRLVERREHIRSINFEQLRRYLMDRMLDQNTVSELREVLTLYARIDSIVQRYNEIEALRQKIYNQQTQIRGNLDVLKNEGGEGELRTRYITTLAETEDQLNGLREEEVTLRSEEAACHAKLEEHLSRFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B597</accession>
    <name>A9B597_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3598"/>
    <dbReference type="EnsemblBacteria" id="ABX06234">
        <property type="protein sequence ID" value="ABX06234"/>
        <property type="gene ID" value="Haur_3598"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3598"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_4_0"/>
    <dbReference type="OMA" id="TRATMEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3637-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="23185" checksum="98C8590F7A23E2C1" modified="2008-01-15" version="1">MRLIVVRHGETAWNAERRYQGHLPIPLNQRGREQALCAGQRLANLAIDHLYASDIARAWETATIIGEQIGLTPEPLIDLREINDGDWAGHTPEELHDLFPDHMQLIKLNPDSTQRLNGESYAELQQRMAKAFEHFAANHRGQTVVAVSHGGAIRALVCHLLAAPLRHFGRLWLDNGAFVEIVAHGDEWRVLRVNDAAHLDGVFAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K0</accession>
    <name>A9B5K0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1590"/>
    <dbReference type="EnsemblBacteria" id="ABX04233">
        <property type="protein sequence ID" value="ABX04233"/>
        <property type="gene ID" value="Haur_1590"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1590"/>
    <dbReference type="HOGENOM" id="CLU_1218411_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1614-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="25142" checksum="E0F07D8D5CE0FA73" modified="2008-01-15" version="1">MNQPPEPYPAETLREQAQAFPYPPTPNLQIKQVRRTVWSKQLGWALALGIMLSLSIPAVRAQVGRWLQVGTILIGVDSPSTNVPLPTPAQTASPPIKPSTLPSSSLLGPPDQILQLEPYPHVQRLIWFSQGQTITLDLLDSQAWASKTILALANVRHTQVHEQAAIWLQGQRELTFFNPSTGQSYKTSNLSNTASLIWADHNRTYRLETASDLATMRDLAESFSQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B683</accession>
    <name>A9B683_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3658"/>
    <dbReference type="EnsemblBacteria" id="ABX06294">
        <property type="protein sequence ID" value="ABX06294"/>
        <property type="gene ID" value="Haur_3658"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3658"/>
    <dbReference type="HOGENOM" id="CLU_1183745_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3697-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="25615" checksum="C0129347B8FB8F67" modified="2008-01-15" version="1">MKCPNCYSNVSNSTEKCPRCDWPLRAPAAATSSAAFGESPTANAWGRDQTNDAGVWEPTMPASAAWEQPTAEPASTWDQAPLQSVAPPPNATMMGNAMPTTVTLTSGQKTQLLFGAFFPLIILAIPIWFIGGSGGSEEISFFWFILGLFGLVVGWQAIMNLADFFSGVAQVQVDRLTKTQVVKNKNSRTYYGHFERIGRLNIGRENYDGAFQGAIYQVTYSPRSKRLWAMQQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B9</accession>
    <name>A9B6B9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3694"/>
    <dbReference type="EnsemblBacteria" id="ABX06330">
        <property type="protein sequence ID" value="ABX06330"/>
        <property type="gene ID" value="Haur_3694"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3694"/>
    <dbReference type="eggNOG" id="COG2096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083486_0_2_0"/>
    <dbReference type="OMA" id="HQACTVV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3736-MON"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="20801" checksum="9683157023CEF2A0" modified="2008-01-15" version="1">MPRITKVYTRTGDNGTTALGGGQRVPKESLRVTAFGTVDELNSNLGVALAVGVSERLQAPLQAIQNELFHLGSDLCMLEEDKQKWPIPQIEARHIEALEQLMDELMDAVGPLENFILPGGSQTSAHLHVARTVCRRAERDVVALSREETIGSFVIKYLNRLSDALFVMARYENFVRNVPDVIWDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6E2</accession>
    <name>A9B6E2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0193"/>
    <dbReference type="EnsemblBacteria" id="ABX02845">
        <property type="protein sequence ID" value="ABX02845"/>
        <property type="gene ID" value="Haur_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0193"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798706_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-196-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="45"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="182"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="35131" checksum="6D79B3707BEA6F85" modified="2008-01-15" version="1">MHKRLTRVLGTIFCVLGLGLALFGFDGAWRAYGQTAGPTPTPDFDLPITKAVSPSNALPGDTVTFSINVTNDQPQTQTNVVITDSVVNFLEVVGASSSKGTASFSGQEVRADVGTLASGESVRLTITTRVRVGTAPGTIGQNVAFVNTASGSSSSSNVVTVTIGGEGTPTPSPTPVPAGSKLVVEKSASPASGKVGDLITFKIVVRNTGGSTAPNVVVNDRILDFLEVVSVQTSKGSAATTGQDVKVTVGDLAAGESVTIAITTKIRAGTVSGQQGINIAEAVASDGSGGSSSIPSNPVAIAVDRNPPAGLPDTSAPNQASWIFWLGLGMAITGGLLLMVSRRRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I6</accession>
    <name>A9B6I6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="9">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmhA</name>
        <name evidence="11" type="ordered locus">Haur_0237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0237"/>
    <dbReference type="EnsemblBacteria" id="ABX02889">
        <property type="protein sequence ID" value="ABX02889"/>
        <property type="gene ID" value="Haur_0237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0237"/>
    <dbReference type="eggNOG" id="COG0279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080999_4_0_0"/>
    <dbReference type="OMA" id="DVHICVP"/>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="37"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="94"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX02889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="20729" checksum="4962B70DD228C801" modified="2008-01-15" version="1">MADYSAYIEKSFREHIAMAERVLAEQSATINTMANVLIACYQQGHKAIFCGNGGSAADAQHLAAEFVGRYLIDRRPIPALALHTDTSTLTAVGNDYGYDQVFSRQVKAHMNPGDVLVCLTTSGNSVNVIKAAEVARELGNPVLALLGGDGGKILPLCDHALVVPFKLPYLVQEISMVVGHLLCDLTEQALFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U5</accession>
    <name>A9B6U5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1761"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04404">
        <property type="protein sequence ID" value="ABX04404"/>
        <property type="gene ID" value="Haur_1761"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1761"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_2_0"/>
    <dbReference type="OMA" id="YERYSLW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1789-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="17"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="390" mass="43372" checksum="B74199C85D303758" modified="2008-01-15" version="1">MKVLYIASGIRVPGAFGGAIHTTEVAQGLAQLGVEMHVITRPAQGQRRKPWQLPKRQTGAITWYEADLPKPLSLLGYSAIARLVRELRPDAVMERYYNFAGAGILAAARQGIPTLLEVNALIVDPPQVRKRQLDDSLAWLLPGKHGPMRRWAAWQCRHSTKIVTPLHTTVPPEIECSRIVELPWGANVQAFSPQTQAPIQPVFVFLGSFRHWHGVTDFIRAAIRLIQQGSPARFLLIGSGPEQAEAQRLAAPYAERFEWAGAVAHERVPALLAQASVGVAPFNPARHPALQAAGFFWSPLKIYEYMAAGLPVVTANIPPLDTIIRPQQEGGLFEAGNINDLARVMQAVANDPQRQQWGLNARQRVVEYYSWERHCQALYQLLQTMIKEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B736</accession>
    <name>A9B736_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="10">1.18.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3267</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3267"/>
    <dbReference type="EnsemblBacteria" id="ABX05904">
        <property type="protein sequence ID" value="ABX05904"/>
        <property type="gene ID" value="Haur_3267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3267"/>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024722_3_0_0"/>
    <dbReference type="OMA" id="RFNFIGN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3302-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021163">
        <property type="entry name" value="Ferredox_Rdtase_adrenod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000362">
        <property type="entry name" value="FNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="9">
        <location>
            <begin position="12"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="202"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="380"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="470" mass="51441" checksum="66BE548B32D9E50D" modified="2008-01-15" version="1">MTTVGTEAQPLRVAIIGSGPSAFYAADHLLKQSDLVVEVDMFDRLPTPFGLVRGGVAPDHQKIKTVTKAFNLVAKNPRFRFFGYVEYGKDLSHADLVEHYHQILYATGAQSDRHMGIPGEDLTNSFPATAFVAWYNGHPDYRHLQFDLSQERVAVVGVGNVAIDVARILCLSHEELARTDIADHALEALSKSNIKEVYLLGRRGPAQAAFTTPEVKELGELEEADVVAIPSEVALDDVSRADLEAGGDKAAQKKVELLQGYAQRAPEGKKRRLIFRFLVSPTEVLGDSDGRVAGLRLAKNELYASESGSIASRATGETEDLPVGLVFRSVGYRGSPLVDVPFNERWGTFLNQKGRIIDPTSQQPKIGEYTAGWIKRGPSGVIGTNKPDAVETVQCMLEDLATGQVLNPSHAERESIEKLVQERQPNYVTFADWQHLDEIEVANGAATGRPRVKFTRIEDMLAALGKNVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7A9</accession>
    <name>A9B7A9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ordered locus">Haur_3756</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3756"/>
    <dbReference type="EnsemblBacteria" id="ABX06392">
        <property type="protein sequence ID" value="ABX06392"/>
        <property type="gene ID" value="Haur_3756"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3756"/>
    <dbReference type="eggNOG" id="COG0445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_0"/>
    <dbReference type="OMA" id="FRPGYAI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="7"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="424"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX06392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="650" mass="71570" checksum="671DEFF426CB7C7A" modified="2008-01-15" version="1">MLNLTYDVVVVGGGHAGCEAALAAARMGSQTLLLTIDLDKLAHMSCNPSIGGPAKGNLVREIDALGGAMGVITDRTLIQIRLLNETKGPAVQALRAQSDKRLYAKAMKEFLEAQPNLALKQAMVERIIPLADQADGARFAVETQTGWQYRAKALVLTTGTFLRGRAITGESIIPAGRMGEQPAINLSSDLSQLGFPLVRLKTGTPPRIDARTIDFSGLEIQPGSSTPLYFGFNYDGQRPESLVHGPPNPIYPEPMLDGWQPQLPCYHIYTTPEFHQHIRDNLHRAPMFSGVIEGVGPRYCPSIEDKIVRFADKESHGFFLEPEGWETLEIYVQGCNTSLPEDVQWAMLRSIPALRKVEIMRVGYAIEYDAVATGEITASLEAKRLPNLFFAGQINGTTGYEEAGAQGLMAGINAALKVAERAPFILRRDQAYIGVMIDDLVTKEIREPYRMFTSRAEHRLLLRGDNADLRLTPLAAELGLVSAERAAQVERKQWAIDQASQQLRGLRYTPSAETNGRLQAAGIEPLLQPASGEDILRRVGVKYAQLAEVQPDLPVVEADVAEQVELSAKYAVYIAKEQASVERVRKMEDRRLPADLDIEAIPSLRIEARQVLKRFRPATLGQASRLAGINPADIAHLLIHLERRERATVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B9</accession>
    <name>A9B7B9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3766"/>
    <dbReference type="EnsemblBacteria" id="ABX06402">
        <property type="protein sequence ID" value="ABX06402"/>
        <property type="gene ID" value="Haur_3766"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3766"/>
    <dbReference type="HOGENOM" id="CLU_1633139_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3808-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="162" mass="18346" checksum="0633E68A399CC5EE" modified="2008-01-15" version="1">MSSAHISGRLLIVTLGSIILYLIYNIGSIFLIDPRTYPTLFIVVTVFGVVGFGLGIYLAARWALKPRRYRETERIGLLVQAQVIDCVATGWKHKQSRGFATGISEREYRVTVELNQPDQPRSQATVYGYFPNNQIPRRNQYLSLRIHPRDPKIVVLAKAATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7H8</accession>
    <name>A9B7H8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0299"/>
    <dbReference type="EnsemblBacteria" id="ABX02951">
        <property type="protein sequence ID" value="ABX02951"/>
        <property type="gene ID" value="Haur_0299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0299"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_0"/>
    <dbReference type="OMA" id="YAYQMAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-302-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="97"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="35969" checksum="B1A17ED499B182BA" modified="2008-01-15" version="1">MALAPKKNKLSLWQRIRQNSLAYKFIAPTFVAMMIVHLIPIVQGLYLSLLDVRLTTLTLYLKAPFVGLKYYIEVFNAIFGIGEAGASSRVTGLINAASNTLVYTIWTNIGTLGLGLILAMLLNREFRWRGIARTLVLLPWVVPTFVTGTIFNFIWLEQGGLANKILLGLNIVDTPVTWLIGPNSLYALVIATVWRGLPFTTIMFLAAIQVIPTDLYEAASLDGANGWQRFRHITLPLIKPIAGTQVLFGLINGFYGGYNIAVQMFGGGTGFAGEYADLLVPAITRQTWERHLYGFGSAASVILMGMLLVFVGIWYRAFRDSLRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P1</accession>
    <name>A9B7P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04419">
        <property type="protein sequence ID" value="ABX04419"/>
        <property type="gene ID" value="Haur_1776"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1776"/>
    <dbReference type="HOGENOM" id="CLU_3184549_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1804-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="46" mass="5124" checksum="F5187948D6A86591" modified="2008-01-15" version="1">MQQAPLLQASYRLAKAFGWTPQEVQALTMAQITLYLQLLAEDVGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U8</accession>
    <name>A9B7U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1833"/>
    <dbReference type="EnsemblBacteria" id="ABX04476">
        <property type="protein sequence ID" value="ABX04476"/>
        <property type="gene ID" value="Haur_1833"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1833"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1861-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="15567" checksum="F603A7D07CC2C6FE" modified="2008-01-15" version="1">MLTATTQISAGVIEDNPQNLEIARVCLIHQLHAHYQGGWRSGQSFFTWHDEHPKIGFDLLLLDIHMPKESGIKLYQELRELLPKTKIIAWTADVVPQRVVLYQQVGFDGMIGKPINTKRFPLQIQRILAGEAVWEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X5</accession>
    <name>A9B7X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1860"/>
    <dbReference type="EnsemblBacteria" id="ABX04503">
        <property type="protein sequence ID" value="ABX04503"/>
        <property type="gene ID" value="Haur_1860"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1860"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_4_0"/>
    <dbReference type="OMA" id="FERERHW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1889-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1321"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1416" mass="153095" checksum="7DA8EAA9EDB5B334" modified="2008-01-15" version="1">MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPAYVKRAPLLLDDIAGFDHNFWGITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGVFVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPTRISFKLNLLGPSVSVQTACSTSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGTIGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALALAEVEPSMVGYLETHGTATNLGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAGVAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTASAWDANLYAGVSSFGIGGTNAHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQTARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQAPAFRQAIDLVNRYAQPLLGYDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQLPSGAMLSINASRDQIQPILPAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFRQHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTLATFARASQAAQTPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQALHQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINTPTWQAQSLATTPIQASTWLVWGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAADLLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWLDLDFTHQAWPSMLAQELQSASEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGGNGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWKLDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADPQRLSFEQGWAALSAIVQQRGVLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFEAPRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLATQVLGRIRQQLQLDLPLQLLFEAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B813</accession>
    <name>A9B813_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative [LysW]-lysine hydrolase</fullName>
            <ecNumber evidence="1">3.5.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysK</name>
        <name evidence="2" type="ordered locus">Haur_3310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:48684"/>
            <dbReference type="Rhea" id="RHEA-COMP:9693"/>
            <dbReference type="Rhea" id="RHEA-COMP:9715"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:78525"/>
            <dbReference type="ChEBI" id="CHEBI:78526"/>
            <dbReference type="EC" id="3.5.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family. LysK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.130" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3310"/>
    <dbReference type="EnsemblBacteria" id="ABX05946">
        <property type="protein sequence ID" value="ABX05946"/>
        <property type="gene ID" value="Haur_3310"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3310"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_0_0"/>
    <dbReference type="OMA" id="HMDTVPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3347-MON"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01120">
        <property type="entry name" value="LysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010175">
        <property type="entry name" value="LysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01902">
        <property type="entry name" value="dapE-lys-deAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="37353" checksum="BEE60D5B584EF9A1" modified="2008-01-15" version="1">MNDQQALQLIEAMVATPSVSGDEAAIAQLLVEQMNQLGFDAHIDAVGNAVGVIGAAAETVVLLGHMDTVPGNIPVEVRDGELWGRGAVDAKGSLATFIAAAARAHAEQRLTYRVIVVGCVEEEVASSKGAHFVAQTMAAPLWCIVGEPSGADRLTLGYKGNLRAQIRIEQDAAHSAHASHTAAEHGCELWQAIAQHAYSINQGRERAFDQLLPSLVKIESGGDGLRDWCELLVNVRLPLDLDPAAYTAMLQQLLPNYAHLKVSGATPAFSSERTSSIARRFGRVFRANGQQPRYVQKTGTADMNVVGPAWGCPVVAYGPGDAALDHTPQERLPLAEYLQAIAVLTAVLSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B855</accession>
    <name>A9B855_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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            <dbReference type="Pfam" id="PF01575"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="132" mass="14200" checksum="BE4C31A7BFF2DA47" modified="2008-01-15" version="1">MSYTIGQSARLRKTITEADIILFAGISGDANPVHIDEIAARESRFGRRIAHGMLGAGLISAVIGMHLPGPGTIYLNQTLAFRSPIYIGDTVTAYAEIKSLRDDKPIATLITQLLNEEAKILIEGEAIVLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A3</accession>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15577" checksum="DB79958E6F00F930" modified="2008-01-15" version="1">MEFVIMQFTVLAASIKRGLGEHGTAIRLFGSALGLLIAGQLCYRKALLGATQHNLESLWQVSQSFWGMLGIGLILLSLFPWLALLARRQLSFFYPLWSIATIVLVVINWWWFGGGMSWQTLAGIGLVLLGVSLLFRGGHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <name>pHAU01</name>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07725">
        <property type="protein sequence ID" value="ABX07725"/>
        <property type="gene ID" value="Haur_5097"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5097"/>
    <dbReference type="HOGENOM" id="CLU_023845_4_0_0"/>
    <dbReference type="OMA" id="ITTCRGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5159-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="38029" checksum="9F5943AED55BED9B" modified="2008-01-15" version="1">MDVSIIIVSYNSQDDLVECLDSVIQACPDQTRYEILVVDNDSQDASRLVVQQQYPMVRLLENSNTGYAGGNNYGAAMARGEYLLFLNPDTVVMPGAIDALVAPFKTDPTIGLTTACLVHHQHPQSINACGNEMHYTGLTYCRGANQPRTAYQTSSYVDAVSGAACAIRRSLFTTLGGFDQQFFMYVEDSDLSLRVRLYGLQCFYVADAVIQHKYHMKYTAQKAFLIERNRYSMLIKNFSPSVLGRLLPGLLLAEVITGSYFLLRGPQYWSIKPRLYQHIWRYWRTTSTPATSPIQELAVVKALTSQLNFQSLHQGRVTRLLAGMVNPLLGLAHRFAGGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z7</accession>
    <name>A9B8Z7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07811">
        <property type="protein sequence ID" value="ABX07811"/>
        <property type="gene ID" value="Haur_5184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5184"/>
    <dbReference type="HOGENOM" id="CLU_504112_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5246-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="540" mass="60861" checksum="7FD935A310DBC480" modified="2008-01-15" version="1">MNAYRSRSHWRQRIVLFIAVTILIAGMAQPYKLNAARSFSISHGMVDDSTFENSFWIAMHAGPDNSGNTEINTAPKVFEKYFQASQWHPGNKPTFYGLGEGNGYTKTALSFATFYMAETTGPRYPGQPLTDIDGWHYTPSPQYVAMLNAAANAQPPRPIFVHFNGSRWMEPNEQPCDAAHTSLWCMFNHTMQDNLQFDQFNQAFTGTAANGLGKCVSGQCYLSIARGANPNSDTATYARLYKKRNLQEAVRYLLEWSNNNPGRLVAITLDSETAQAAVERQPFPRIGDYGPQATMQYRTEMQWQFNFNLTAYNQTFSSCQPAITNWEQLWPPVNADSLATMTNINTLNPCWQSWQNFRVHLVQQMVSDTARWATEVGMPKSRIYTHQAISDTFLDYMYDASPISTAKNSYSQVGLDFYEKQLFTTTSNGSLTTKDSLMQEAQDLAVGSAWGIPEFNAGLGPNAWGGAARQGPVLSKCQPQHDAEIYDRTYSSLYKAYLKGARVVMPYLWNPSDGTVIEQWGIGSCWPAMRAYRDFLRNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B951</accession>
    <name>A9B951_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5238"/>
    <dbReference type="EnsemblBacteria" id="ABX07865">
        <property type="protein sequence ID" value="ABX07865"/>
        <property type="gene ID" value="Haur_5238"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5238"/>
    <dbReference type="eggNOG" id="ENOG50313GU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150007_0_0_0"/>
    <dbReference type="OMA" id="AWTWPRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5300-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046289">
        <property type="entry name" value="DUF6326"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19851">
        <property type="entry name" value="DUF6326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17295" checksum="7816EDE759FC001C" modified="2008-01-15" version="1">MNNKDTAMNAPKQPMTPLADGHVPVQAKLAAAWTSFMFLYIYVDYFHLYKPGAIDQIRSGVVFEFAISPTYLTTVLALVSISALMIVLSMALPARANRITNLIVAALEIPFAAINAVGESWDWASFYGLSIGIEVLLLLFILRAAWTWPRTTAATTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUG1</accession>
    <name>A9AUG1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="8">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="8">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckG</name>
        <name evidence="11" type="ordered locus">Haur_0429</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
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    <keyword evidence="6 8" id="KW-0464">Manganese</keyword>
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        <location>
            <begin position="14"/>
            <end position="235"/>
        </location>
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            <end position="590"/>
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        </location>
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</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUZ8</accession>
    <name>A9AUZ8_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="gene ID" value="Haur_3954"/>
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        <property type="component" value="Chromosome"/>
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    <keyword evidence="2" id="KW-0132">Cell division</keyword>
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            <begin position="131"/>
            <end position="282"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Pfam" id="PF01580"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX06586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="393" mass="44230" checksum="BCBB8AB0E6D99544" modified="2008-01-15" version="1">MLGFIWDNVAPLLFLWSMIGCMLAHRHWTQVLRVCQFLRTIPPQIETVWKTPPQTHNPQENNFSIHSQPTQACLIKPTFTHLKTIPETGMALLNPPTLNATFDYLQSIEPQARYLLPYGWYIPSNQGQMPDAAYADLGADTYNVAIISPEGYGKTAWVLSGMMALMLQRTPRELQFVIFNTKDADINLMENSAYTLLFAQSIQGILDSIKQLHAEAKRRAEVLAAHHVLTWNTYHGDDLPLIVVYIADPTAISSAIGKKLVEKALTLLMMYGPALGFRIIIESRNMSDLAPCYHHFFSDRLLGPMDKDPIFQQNGKRMPIRTIFNNSAIAPTQLPNEYPGVFTAVDAHGRAVTLRTVYISPEAQKDWMISQSKDLQTLTTTQEPHGSSIPQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV31</accession>
    <name>A9AV31_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03109">
        <property type="protein sequence ID" value="ABX03109"/>
        <property type="gene ID" value="Haur_0458"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0458"/>
    <dbReference type="HOGENOM" id="CLU_1439269_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-464-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20679" checksum="665482B83EF46487" modified="2008-01-15" version="1">MQRLIVAMLLLVILIGCRQQQTTQPLTPSPINSIDSRKIEAIILKPFQNEQIQNLQMYPVAGLNEGMLFVYQLDSARGKAIGLLTGVETLGEFSIRSQSLDILGPQKPYGFYLSNDGGQPNYIGYGYIQHPETIKQLRIILSDGNSLVVTGNTITGLVMPKHNPPIRLEVVGIDGTIIEQNPITLPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV85</accession>
    <name>A9AV85_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase/kinase involved in NAD metabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0514"/>
    <dbReference type="EnsemblBacteria" id="ABX03163">
        <property type="protein sequence ID" value="ABX03163"/>
        <property type="gene ID" value="Haur_0514"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0514"/>
    <dbReference type="eggNOG" id="COG1056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052648_0_0_0"/>
    <dbReference type="OMA" id="QDPFRYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-522-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="154"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="38856" checksum="A36FFCDEF55F2F24" modified="2008-01-15" version="1">MRGLTLGKFAPLHKGHQLMIETALSEVAELQIIIYDSPEQTSVPLPVRSAWLRELYPQAQVIEAWDGPSVIGNTREIQQLHEDYVIQQLGISNISHFYSSEFYGEHMSQALGAINRQVDPPRNQVPISATQIRSDPYRYREFLHPRVYRDLIMKIVLLGAPSTGKTTLTATLAETFNTQWMPEYGREYWEQHQSNRRLTPQQLVEIAEGHREREEQRLLESNRYLFVDTNALTTYHFALSYHGRAEPRLAQLADQAQQRYDLVLVCDSDIPYDDTWDRSGEVQRTIFQKQLFAQLQQRRQPYYLISGPLEQRIAQVQSLLQRHQLYHNLLANPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB2</accession>
    <name>A9AVB2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0542"/>
    <dbReference type="EnsemblBacteria" id="ABX03190">
        <property type="protein sequence ID" value="ABX03190"/>
        <property type="gene ID" value="Haur_0542"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0542"/>
    <dbReference type="eggNOG" id="ENOG50331F0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_666940_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-551-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="48475" checksum="ACBD7BCDFC7B3B6B" modified="2008-01-15" version="1">MTFVLGFKRFTYLGISMMQPLTNISKAVDRIIESLPQLQPVLESTTYRLGDDSIIIRNKYPEYRNQLKLHKDLLSNIILEELDNKEFNFIIDESDINFIEFDRISSKRSVSKNINHNFNIENNINLNFYTSQSIDVIDSGISQYLDDFKKRMVWPHYKIIRKKENSSKIVYEISFISIGELGFITDMTGKIYLRKIGGGGFNIKYINPFHIKDNIDKLVEFHLEEFDKIKKWHNFEIDILESSIDSSRNIIVISREIFEYIEYSLKEDEIIEDNDLYRINRNNEYYVNLDRIKELSKIQSKDFDITKLVKLCLELNISFSNECYFAAIFILRAIIDHIPPIFGHINFDNVVSNYKGNSGKKILNHLLVTLKNTAHINIHKPISRKEIIPNRQQVDFKSEIDFLLSEIIQELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI1</accession>
    <name>A9AVI1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aconitate hydratase</fullName>
            <shortName evidence="6">Aconitase</shortName>
            <ecNumber evidence="6">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="6">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2029"/>
    <dbReference type="EnsemblBacteria" id="ABX04672">
        <property type="protein sequence ID" value="ABX04672"/>
        <property type="gene ID" value="Haur_2029"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2029"/>
    <dbReference type="eggNOG" id="COG1048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013476_2_1_0"/>
    <dbReference type="OMA" id="EAQTVMF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2058-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="7">
        <location>
            <begin position="82"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="8">
        <location>
            <begin position="686"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="895" mass="96728" checksum="77E50720EFF46136" modified="2008-01-15" version="1">MQTVNPAFQRSLECAGQTYRVWSIQALASSYQLELETLPFSLRLLLEAQLRAFGRGLSDLAAIEALINQLQQPDIAQPKVVIPYLPARVLLQDFTGVPVFVDLAAIREAVAEAGGDPSLVNPVVPTDVVVDHSIIVDVAGVPNAFAINTRYEFERNQERYHLLRWSEAAFKHVRVFPPGSGIVHQINLEHLATVVQTQVTATGELMLPDSVCGTDSHTTMINGLGVLGWGVGGIEAEAVMLGYPLMLTLPSVVGVELTGSLRPGVTTTDLVLSLTQRLRQAGVVEQFVEFCGTGVNQLSIAERATIANMAPEYGATCGYFPVDAETIRYLQTTGRSAELIQQVEAYYQFQGLFRQPNAQLPQFAKLIQFDLATVEACVAGPARPQDRLSLRAVPASVVAATQPKQQPITVALDDQTYRLDHGALLLAAITSCTNTSNPAVMLAAGVLAQQAVARGLRVPRYVKTSLSPGSRVVTTYLQEAGLLPALETLGFQIVGYGCMTCSGSSGPIHPQLSQAVAEQGLMASGVLSGNRNFEGRIHPAIRLNYLASPPLVIAYALAGTMNIDLETEPLGYGSDGQAVYLADIWPREQTIQALLANLIKPSMFHKHYQQPVIPAEWQAITIEKTLFYPWATQSTYLKRPHYIHGKSNQSPSIIKDARVLALLGDSITTDHISPGGAIDPKGEAGRYLLEQGVAPSDFNAYGARRGNHELMVRGGFANARLKNQLLAGIEGGFSLHQPSGQQDTIYATAMRYATTNTPLIILAGNEYGSGSSRDWAAKAPKLLGVQAVLAASFERIHRANLVCMGILPLEFMAGQPWQSLGLNGAEFYTIYGLDALVAGGECVVEASDADGNVNRWTMRVRIDNPSELRTYYAGGILQQVVQRLALPQAKQVNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR8</accession>
    <name>A9AVR8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4036"/>
    <dbReference type="EnsemblBacteria" id="ABX06668">
        <property type="protein sequence ID" value="ABX06668"/>
        <property type="gene ID" value="Haur_4036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4036"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="QIISEVW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4079-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="145"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="145"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="28449" checksum="A3E85DC9CCB263FE" modified="2008-01-15" version="1">MRLLNRTNERHEDNNPHQRKILVADDDPAILRLVEVALSGQRYQLVTVSNGLEALKMYRDGEYQLLLIDVMMPYIDGFTVTERIRARSDVPIIIITARDGTDDVVHGFELGADDYITKPFRTAELQARVEAIIRRVEGYQHRKASPIVRIGDLEIDEPRHKVLLAGEDVNLTPMEFELLYFLAANSGQVFDREVLFREVWGYEYVGQTNLVDVCVRRLREKIEEQPSKPRRILTVRGVGYKLADGGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY3</accession>
    <name>A9AVY3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03221">
        <property type="protein sequence ID" value="ABX03221"/>
        <property type="gene ID" value="Haur_0573"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0573"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_1_0"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-582-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="8"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="20203" checksum="D777A48F10AC6F16" modified="2008-01-15" version="1">MAKLHPELTPELQAFIAQQPLFFVASAPLAADGHVNLSPKGLDCLRIHSPQQVAYLDLTGSGNETSAHMLENGRITLMFCAFVGAPRILRLYGRGRVILPTMAEWEPELAQFPHYPCIRQIVLVAVERVQTSCGFGVPLMELVGQRDTALRWAEAKGEQGLATYRSEKNLASIDGLPTHLASEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW20</accession>
    <name>A9AW20_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0610"/>
    <dbReference type="EnsemblBacteria" id="ABX03258">
        <property type="protein sequence ID" value="ABX03258"/>
        <property type="gene ID" value="Haur_0610"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0610"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-619-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="53"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="27271" checksum="DB48D5D80657A6AF" modified="2008-01-15" version="1">MSNTPKPRQGRQRVREKRSLLPFYLMLGLVGIVGLTFVFIQALQTPVAPPSASIPIRPVINAAIGQTSEGYWYKGDPNAPIKVIEFADFECPGCRQLEVDLANANFDAEYIETGKVQWIYREFPLRSIHKSAQYTAEVSRCAGDQGVYWPVHMALYDSQLQWTNLDNPNPLILDAAVKAGANLDKLEDCMDAETHTAAINASYDSAKSLGLDQTPTVFINDDRINFVGDFYTDLKLAIDAKLGVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW57</accession>
    <name>A9AW57_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2066"/>
    <dbReference type="EnsemblBacteria" id="ABX04707">
        <property type="protein sequence ID" value="ABX04707"/>
        <property type="gene ID" value="Haur_2066"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2066"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_4_0_0"/>
    <dbReference type="OMA" id="RIDLMAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2094-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="32090" checksum="98589FA9C3E49E7D" modified="2008-01-15" version="1">MDWLIEPLRYTFFLRGMVVGMLMGLTCGVLGCFVVLRGMAFIGDALAHAVLPGVVLAYMGGISMVLGALGAGLFAALLISLISRTDYIREDTAIGIVFTGAFALGIVLLSRMRGYARDLTHFLFGNILGIAPSDLLLTGLVTASVLGAIGLWYRPLMIMTFDPTHAKAIGLRLGRWHAGLMVLLALTIVSGIQAVGVVLVAALLVTPAATARLLTNRLPTMIGLAALFGSSSAILGLYASYMLSIASGGVVVLASTGVFAVVFLLAPTHGIVSRRIRQWWPRFTQTPDVITNEANSETGIDPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH7</accession>
    <name>A9AWH7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="11" type="ordered locus">Haur_4104</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4104"/>
    <dbReference type="EnsemblBacteria" id="ABX06736">
        <property type="protein sequence ID" value="ABX06736"/>
        <property type="gene ID" value="Haur_4104"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4104"/>
    <dbReference type="eggNOG" id="COG1198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013353_3_1_0"/>
    <dbReference type="OMA" id="RCHYCGY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="297"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="829" mass="93078" checksum="9DABC9D1D3E06D4F" modified="2008-01-15" version="1">MYAQVALNAYLPDNPEAILTYAVPPHLRPLRVGALVWVPLGPRRVQGVVLEFSTQRPQGFVVRDILEHADPEAIAAPAQLALAQWFSQSQAVRLWDAVQLTMPPGVKQEIERTWRPTEHGQKIELGTLDERERAILFHLRRVGEQSERQLRVDLRGSDADLRRSYTELHERGLIALGSLVSRPAAKPKREWSAQPTSATPAEALAELSKAPRLAAIFQAILEQAVDGEPVLLPELRDVGASLSHLRSLALRNLIQLEQIEVRRDPLLGRIPPLEFPPELTLEQERGWRQIVAAQDTASRTGKAKPILLHGVTGSGKTELYLRAIGRALRNGGQALVLVPEIALTTQLVRRFAARFPQQLAVLHSELSVGERYDEWRRLRRGDAQVAIGSRSAIWSPMSKLQLIIVDEEHEHSFKHEATPYYHARDLAVKLAELAGAVLILGSATPSLETAYAVQINKYEVLELHERVGRKTVAGVTKADPIPMPPVQIVDMRSELKAGVRSMFSRPLQSAIQRTLDKREQTILFLNRRGIASFVMCRDCGTTIQCPRCAVALAVHATAGDAAAPATLRCHYCGHVDWVPRNCPSCFSTRIRDFGVGTQRVVEEVKLLYPQARVMRWDRDVTGRKGSHEALLNQFTQHEADILVGTQMVAKGFDLPLVTLVGVITADTALNLPDFRSGERTFQLLAQVAGRAGRRAGGGQVIIQSYNPEHYAIQAAAQHDYRQFYREEIAFRRTAHYPPFSRLIRFMTQSPSNKTVERVVRQFDTQLREELERRRIRDWAIIGPSPAFLQKVRDLYRWHILVRLPDPTDLLHDLKIPSGWTIDVDPVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWK1</accession>
    <name>A9AWK1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4128"/>
    <dbReference type="EnsemblBacteria" id="ABX06760">
        <property type="protein sequence ID" value="ABX06760"/>
        <property type="gene ID" value="Haur_4128"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4128"/>
    <dbReference type="HOGENOM" id="CLU_1914172_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4174-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14953" checksum="2BA4D001BE9F22C0" modified="2008-01-15" version="1">MILQKLAPHKPTVIVWLSSLALISMQLLLPFTTLSFLLAIVIVPGFLLSSYVIWIIFFRPRSLQARLEPRRAHDPTIPRKKPRWRYNTYQDPPVHLPNVHWNPIDPDFIDLESLAPNNSSSSSGGGDSSGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL3</accession>
    <name>A9AWL3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ordered locus">Haur_4140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4140"/>
    <dbReference type="EnsemblBacteria" id="ABX06772">
        <property type="protein sequence ID" value="ABX06772"/>
        <property type="gene ID" value="Haur_4140"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4140"/>
    <dbReference type="eggNOG" id="COG0137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_2_0"/>
    <dbReference type="OMA" id="QCEVVTF"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="403" mass="44562" checksum="63369D8F16C11998" modified="2008-01-15" version="1">MSNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGASACYVEDLREEFVRDFLFPMLQSGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHGCTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDALDYAALHNVPVTSTRASIYSRDGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLGPVALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRETLHFKDTLAIRFSELIYNGQWWSPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAERSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTSGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ4</accession>
    <name>A9AWZ4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chorismate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.151</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthetic enzyme MqnA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mqnA</name>
        <name evidence="4" type="ordered locus">Haur_2162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>chorismate = 3-[(1-carboxyvinyl)-oxy]benzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:40051"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:76981"/>
            <dbReference type="EC" id="4.2.1.151"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MqnA/MqnD family. MqnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.151" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2162"/>
    <dbReference type="EnsemblBacteria" id="ABX04802">
        <property type="protein sequence ID" value="ABX04802"/>
        <property type="gene ID" value="Haur_2162"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2162"/>
    <dbReference type="eggNOG" id="COG1427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059898_0_0_0"/>
    <dbReference type="OMA" id="WGLARTG"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00995">
        <property type="entry name" value="MqnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003773">
        <property type="entry name" value="Menaquinone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030868">
        <property type="entry name" value="MqnA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37690">
        <property type="entry name" value="PTHR37690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02621">
        <property type="entry name" value="VitK2_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="30190" checksum="6578DB55C783EE2F" modified="2008-01-15" version="1">MLGVIDYLNTQPMDYGITERLPHVPVQRGVPTAINAAVLRGEVAVAPMSVYEWALHADELLVVRDFSIATIGAVNSVNLFSWSADPRQLDGQPVALTTDSATSINLLRVLCERHYRIQPEWRSMASNLDAMLAECQAGLMIGDKALVEAATRRHLGERGLPYCFDLGDEWLKLSGLPFVFAVWVVRRDQAEAVREAGIVPALRAAKAENLTRIDELAQLYAPRISVSPGVCAKYLRDLRYHLTSVDLEGLHTFLRYAVPSFQPSQLEWFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX17</accession>
    <name>A9AX17_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2185"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04825">
        <property type="protein sequence ID" value="ABX04825"/>
        <property type="gene ID" value="Haur_2185"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2185"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_667209_0_0_0"/>
    <dbReference type="OMA" id="HQAGSYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2213-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="45227" checksum="06F50094F615A907" modified="2008-01-15" version="1">MPNRGLRLVIVTTFPPSTGTLNEYAWHFVRAFQQKREIREIIVLADELARPEPELPNQINGISLQIQRCWQFNRWDTAQRLMREIEQINPDAVLFNLQFATFGNRRIPAALALLTPALVRQKGIPSIVLLHNIMDTVDLKQAGFAGNQLINWLTKFAGRIITRQLLRADLVAVTIPRYVEILEQTYAATNVLLAPHGAFETPPPPTAPSTDCWRFLAFGKFGTYKKVETLIEAFAQVQTKHQQPMELVIAGSDSPNAAGYLNTVQQQYAHVPNVLFTGYVPEEAVAGLFQSATAVVFPYTSTTGSSGVLHQAGSYGRAAILPNLGDLADIISEEGFDGVFFEPENVTSLALALEQLLLDPARCHALGMQNYAAACGLPISDVADWYLLHLQTLLRQPAIAPRFQQEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX73</accession>
    <name>A9AX73_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2241"/>
    <dbReference type="EnsemblBacteria" id="ABX04881">
        <property type="protein sequence ID" value="ABX04881"/>
        <property type="gene ID" value="Haur_2241"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2241"/>
    <dbReference type="HOGENOM" id="CLU_2058136_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2269-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13135" checksum="D40D46F8CAE9642F" modified="2008-01-15" version="1">MRMVNVTKNNRWSLLIARILNALSFGLSLMLFYPSLQSNQLYTVLGLVVAIGMLWLTKRLTSNPAEYQARGIYLHVALVLSLLVIGFGFGFSNLLLLGGSLIWAVVGLVDGAIRLRKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB4</accession>
    <name>A9AXB4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone family protein DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4202"/>
    <dbReference type="EnsemblBacteria" id="ABX06834">
        <property type="protein sequence ID" value="ABX06834"/>
        <property type="gene ID" value="Haur_4202"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4202"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_2_0"/>
    <dbReference type="OMA" id="RDRVNIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4249-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="10632" checksum="7A0E9A79725BDAC6" modified="2008-01-15" version="1">MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQGVNPKTRERMTIEATKTPGFSASNSLKLLVRQGKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL2</accession>
    <name>A9AXL2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0778"/>
    <dbReference type="EnsemblBacteria" id="ABX03426">
        <property type="protein sequence ID" value="ABX03426"/>
        <property type="gene ID" value="Haur_0778"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0778"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896509_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-790-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="33556" checksum="DC3D3354F8604A1C" modified="2008-01-15" version="1">MATIKDVAQLAGVSVATVSYVLNDSMPVSEATRNKVLAAVAKLGYQPHRQGRNLQRQRTLTIGVLLPQANLLCELDLATWLLEATNAATSAGYSLLLQPADSQARGDLADGWISFGTVLDPQLPQIWALAPPFEQPAVLCDAAFAAQRAVETLTHAGMQRIGLITLPRSIPGSARWYLGYRRALRRAGIAFDPALVVEPADNRFHDGVAAYEALAASENDYDGLIVCGNQLATGVVMVDHAKVPLIVSHSNTQRGISGFRWPTELWAHTLVRKLLQQLDGSAIAHRTWLNPSLVIGSLGFKEDLDGFNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXX3</accession>
    <name>A9AXX3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iojap-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2299"/>
    <dbReference type="EnsemblBacteria" id="ABX04939">
        <property type="protein sequence ID" value="ABX04939"/>
        <property type="gene ID" value="Haur_2299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2299"/>
    <dbReference type="eggNOG" id="COG0799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092688_5_0_0"/>
    <dbReference type="OMA" id="VVHVFQK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2327-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="91" mass="10216" checksum="3F360012C26BDA8E" modified="2008-01-15" version="1">MLDVRPLATFADFLVICTAGNERMVRAVVKEIDDQLVQEGAATPKIEGSPETGWVLLDFGDVVVHIFSPEQRDFYKLDKLWQKATPVVVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY7</accession>
    <name>A9AXY7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2313"/>
    <dbReference type="EnsemblBacteria" id="ABX04953">
        <property type="protein sequence ID" value="ABX04953"/>
        <property type="gene ID" value="Haur_2313"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2313"/>
    <dbReference type="eggNOG" id="ENOG5033T9D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009589_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2341-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732231" evidence="1">
        <location>
            <begin position="20"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="814" mass="89759" checksum="8AC262181C7086EE" modified="2008-01-15" version="1">MRRISSLILLMILVGCGVAAPAPTNPAVTSVSGEATNLPPDSTKTSLPVIMTGDPNAHPRLWLTQADLPRLRAWASDSNPMYRDGLKLVAEEAKITMDAGDVPIRDCGSTEYEEFPTEMYAELFAFMSLIDPNEAARADYAQRARTLLMYIINIAAQGPAENDDYLCPETQSTGYPPFRSPRFFTEDSNRARWHGEAFPLVVDWIYPVLSASDKAAIRGVFLRWSDEIVQRAYHHPEPVGVINDPSLIADTAQVRWSGNNYFVAHMRNLGMMALAFDANDDPNNQLRDYLNNATGAWLYIFDHLTRTDSKGGLLPEGFEYSPQTASYAIQFLLALQTAGKDTCGPHCKLTENPFWDDFVTSYLHSLSSNPTEDPNHGLVYQPAWYGDAQSYHLVDFINAFGSLGIYDQRTGNAARLAKVRWIETVTPPGGAEGLIERVGNPNDFRDAIIYFMLFDPTAAVASDPRPSLPLDFYAEGMHKIFSRTSWADDTGWFNFSLSWNFIDHQQADGNHFEWFRNGEWLTKARTGYADIAEGIASSEFRNLIALENDQPDRDPSDWRIDLWQRGSQWNLVPTGDPNLVAHSLDSRFTYALGDATNLYNSENEATTDISHASRSIVWLKPDTIVTYDRGTSQTANRFKRWWLQLPTPATVNGNRATMTTAGGQTLNVTSLLPAGATLSAVNIADQQSENTAASDDPMKVRLRIDAPGNPQDVRFLQVLQAANSGVTPANVSLIQASSGNYAGAQIGSQVVLFPINLDQAFATIEYSTANAANLQLITGLQPNTGYTVQRNGNNVSISQGGSQMSDSGGVLVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY24</accession>
    <name>A9AY24_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4274"/>
    <dbReference type="EnsemblBacteria" id="ABX06906">
        <property type="protein sequence ID" value="ABX06906"/>
        <property type="gene ID" value="Haur_4274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4274"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099338_0_0_0"/>
    <dbReference type="OMA" id="DWIHRLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4326-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24501" checksum="0419215BC1C457AF" modified="2008-01-15" version="1">MSTKIDETSYFAPQVSKSDRKIAVQYRRMFAFGGLAKHLPQGPVLDVGCGAGPGLRYIRSRGATAIGVDPSIYALREAAKLIDVDLVQMDAAPRFPFADQTFGMVLANEVIEHVPDGVEFLLECARVLQPGGMVFLTTPNLWDIRRVLAPLVGKVWSGDTDPTHINLYTPWRLRNDLKAAGFKQPRIKTGFKPIRWLPPHRNPLAIPYPPLIGNGMVATGVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY83</accession>
    <name>Y4333_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0173 metal-dependent hydrolase Haur_4333</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Haur_4333</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0173 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AY83"/>
    <dbReference type="SMR" id="A9AY83"/>
    <dbReference type="EnsemblBacteria" id="ABX06965">
        <property type="protein sequence ID" value="ABX06965"/>
        <property type="gene ID" value="Haur_4333"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4333"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070010_4_0_0"/>
    <dbReference type="OMA" id="WHGHSTW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4386-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00457">
        <property type="entry name" value="UPF0173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022877">
        <property type="entry name" value="UPF0173"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000367185" description="UPF0173 metal-dependent hydrolase Haur_4333">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00457"/>
        </source>
    </evidence>
    <sequence length="241" mass="25724" checksum="2A454DB5CFF9F686" modified="2008-01-15" version="1">MANTTITWLGHASFLFVTPEGKRIVLDPWYEGNPSFPESAKAELEHVDAILLTHGHMDHTGNAITLAQQTKAPVAGIVELIGWVQGQGVDATQCIGFNKGGCIELAGIKATLTTAHHSSSISSGSISLYLGDPCGFILEFSDGCVVYHTGDTCVHGDMALMGEIYQPNVTILPIGDFYTMGPRQAAHALKLIGSKFAIPEHYGTFPALHGNPEALQSELNKLQLNTAIVALQPGEAWTYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF9</accession>
    <name>A9AYF9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ordered locus">Haur_0893</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0893"/>
    <dbReference type="EnsemblBacteria" id="ABX03541">
        <property type="protein sequence ID" value="ABX03541"/>
        <property type="gene ID" value="Haur_0893"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0893"/>
    <dbReference type="eggNOG" id="COG0320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033144_2_1_0"/>
    <dbReference type="OMA" id="IRCESKD"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="61"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="33627" checksum="105BEFE777EE7D52" modified="2008-01-15" version="1">MDTITLFEAPKAAPVAPRRPAWLKARAPIGENYEDVHGLMRELDLHTVCEEAHCPNIGECWNHRTATFLLLGDTCTRGCRYCAIGKGKPKPIDEQEPQRIAAAVAHLKLKHVVLTSVNRDDQADGGAHIFAESIDLIRQQLPECKIEVLIPDFDGNWEALRIVMDARPDVLNHNIETVPRLFRKFRPRANFYQSLELLRLARDLQPSIVTKSGLMVGAGETDEEVLTVMDALRRSDVDVMTIGQYLSPSGDHWPIDRYVPPETFTWFREQGLARGFRHVESGPMVRSSYHAHEHVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV7</accession>
    <name>A9AYV7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4365"/>
    <dbReference type="EnsemblBacteria" id="ABX06997">
        <property type="protein sequence ID" value="ABX06997"/>
        <property type="gene ID" value="Haur_4365"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4365"/>
    <dbReference type="HOGENOM" id="CLU_1842364_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4418-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DZANK-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15309" checksum="119902B04B7E1BBF" modified="2008-01-15" version="1">MLACSYCGGDVPDDWEECATCGWLRDGSLALPLEPLKCPYCGDDVADDWEECPSCGWLRDGSLGIPQPAPPPATVHQRICLRCQAQMTFLGFKQFRESSTSLDILQGRFGSFRQDFQILELHGCGYCGYAELALPHIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY1</accession>
    <name>A9AYY1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="12" type="ordered locus">Haur_4389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4389"/>
    <dbReference type="EnsemblBacteria" id="ABX07021">
        <property type="protein sequence ID" value="ABX07021"/>
        <property type="gene ID" value="Haur_4389"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4389"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_4_3_0"/>
    <dbReference type="OMA" id="PECKYTR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="164"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="793" mass="88355" checksum="2D154D8E2E5D3637" modified="2008-01-15" version="1">MDHKLVIVESPAKAKTIQKYLGAGYRVMASMGHVRDLPKSKIGIDIDNDFSPVYEISEGKDKLIAELKREIKTADAIYLATDHDREGEAIAWHILQAANIGKRKPVYRITFNEITKDSIQHAIRNPREIDANLVDAQQARRVLDRLVGYKISPILWAKVRRGLSAGRVQSVAVRMVVEREREIESFVPKEYWTIEADLSPAGLKKLGKHDIFRAILHARNGKKLDKFAIPSKDAADAVLAALEGANYLVGTVTRKDKRRSPAPPFITSTLQQEASRKLGFSSKRTMQVAQKLYEGVDIGGKDGTVGLITYMRTDSTNVSVDAQTEARTLITELYGKEYVPAKPNIYKTKAKGAQEAHEAIRPTSVVRRPDQLKTALGRDEFRLYDLIWKRFMASQMAAAIFDSTSVDIGAGAGIKTAAGAPFTFRATGSVLKFNGFLAVYNVSLDEGDEDEDKEALLPPLNEGQALDLHDLFGEQHFTTPPPRYTEATLVKQMESEGIGRPSTYAPTISTIVAREYVELVEKKLMPTTLGRVVTDLLVEHFKDIVDYNFTSDMEQRLDDIAEGQRRWVPVLREFYDPFAVRLHAAETEMRNVKREEIKTELPCPQCGTHLVIKWGRNGEFLACSRYPECSWTGDLERDGDGGIHIASQPEIFGNTNCPECDNPMSLKKGRFGPFLACNNYPTCKGIRKVRAQGKDFVVIPPPKPTEEKCPKCNRPMVQKEGKFGPFLSCTGYPECRSIVRLTPNDAPTCPQCGEGKVVAKRARGGRTFFSCTRYPDCTYASNALPVAVSEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ15</accession>
    <name>A9AZ15_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4423"/>
    <dbReference type="EnsemblBacteria" id="ABX07055">
        <property type="protein sequence ID" value="ABX07055"/>
        <property type="gene ID" value="Haur_4423"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4423"/>
    <dbReference type="HOGENOM" id="CLU_1852449_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4478-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="16295" checksum="C281BC4BB27B658F" modified="2008-01-15" version="1">MYHVPKTSRWQYGCLQQSLYLVNIGLYSLMVFLTIFSASKIVRWWLDDPRYELDYATFIWLPIGLLLLSPFIWQRMYALGTLAITGSSLLLLNIFLMVFLRVDFSDADQIGWSVVILFSVAITLVVWYRAKPWRKFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZA5</accession>
    <name>A9AZA5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1003"/>
    <dbReference type="EnsemblBacteria" id="ABX03651">
        <property type="protein sequence ID" value="ABX03651"/>
        <property type="gene ID" value="Haur_1003"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1003"/>
    <dbReference type="HOGENOM" id="CLU_1243981_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1020-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="24456" checksum="E77C5235656895E0" modified="2008-01-15" version="1">MSNNQLTLVMVNESPIFGSMMVYTQNPDLAELAAYRFINQPVHPTTQASFSWNDQSYGFTWVQNVAPVDNIGITTNLIQLWPADESQNNQVTLTQIDDAYTFKDQTKAEITGSLVIVQDSTVGANAVQIGVSFAGSPVFVVASEPNVTATFTPKIDYWIVFGYTVVENGVTITTTTKPQQLVFPSGYDTITAVLDADYHWQISPSVATAGNQNQASAETLEIAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF4</accession>
    <name>A9AZF4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2460"/>
    <dbReference type="EnsemblBacteria" id="ABX05098">
        <property type="protein sequence ID" value="ABX05098"/>
        <property type="gene ID" value="Haur_2460"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2460"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1123336_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2487-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="117"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="27850" checksum="B01CCAAC6A7B98DD" modified="2008-01-15" version="1">MQIKQALEIFMYGEIGIPSVENRSQRHIIDGLTILHVDDVWNQEPHVADEVIVQNHSPAAVLAMLANYQPTADHRITLVDRPASDHAAYHAAGYRHSSNEVLFVRKLSDLPPPDQRYSVGQAKTIAEMQWLNNNDPAKRAWISETRLHESGLRHSFIALDQRVVARVRACRIDAEHSYVMNLYTASDYRRRGIARALMIHVLHEAAAHGEQWSVLVASEAGLPLYQALGYQQRASLVVFEPVAEPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK0</accession>
    <name>A9AZK0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2506"/>
    <dbReference type="EnsemblBacteria" id="ABX05144">
        <property type="protein sequence ID" value="ABX05144"/>
        <property type="gene ID" value="Haur_2506"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2506"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029703_1_0_0"/>
    <dbReference type="OMA" id="EKFEVPF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2534-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="172"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="453" mass="51234" checksum="2774BE4C63943CAF" modified="2008-01-15" version="1">MSAFPLREFASTVQASVDSGPQFPNEPTSIDETGLGMGFIADLVLKVIYFNGTISAQRISEQTCLPYLNVIDKVLQFLKMSEYVDIVGAEQGFGERAYQYVTTLQGSRKVNEVLERSQYAGPAPVPLASYIEMVNRQSIGGMTINQQRIREAFKDLVINDEMLDKIGPAANSARSLFLYGPPGNGKTTIAEGISRIMGGSVMLPYAVEIDGQVIKLYDPLNHSILTKPEMRQDDTPAPFGAVATTMPPAPDRRWLHCKRPRVMVGGELILEQLELIFDPISKVYEAPYQMKANGGLFLIDDFGRQRCRPEELLNRWIVPLEKKIDFLALQTGKKIEIPFDVLIVFSTNLDPKGLVDDAFLRRIRHKIEVANPTPNEYRDIFRIVCKAKGVPYSDDGLRYLIQEHYFKVNRELRCCHPRDLLDQVLDEAKYRGQQPQMNKELLDRACEAYFVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK6</accession>
    <name>A9AZK6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2512"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05150">
        <property type="protein sequence ID" value="ABX05150"/>
        <property type="gene ID" value="Haur_2512"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2512"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429474_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2540-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734448" evidence="2">
        <location>
            <begin position="25"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="6">
        <location>
            <begin position="28"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="311"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="398"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="502"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="637" mass="68869" checksum="623291AF04BAFF33" modified="2008-01-15" version="1">MKVYKPMLKFIAAFLVFLPLVTSAASSTEHFNQPISSSSMFSWYTNSSTATGTANVSDSQAQDGKILRLSIAAGQTAYPGQGSNLVSRQMYHYGTYEARMKTANCASDEGVINGFFTYFNDGSDSNANGLPDNSEIDFEWLCAEPQSILMTIWTDYNDPTAISRRVYRKVNLATGTIEYTRYATTFGDSYTDLSNSPSENQPTAVQAISGYNSATNYYEYGFNWTASNVTLWVVNPSNGQKIVLWDYRGPSARIPKNPAAFMVNLWHHPNWTPECCANATNPPRATRSMDVDWLRFTPQSDIPSDTTAPSAPSNLQAPSKTHNSVNLSWNTATDNVGVVGYDIYQNGGANPVASTSSTTITISGLNPSTAYSFAVKARDAADNRSANSNSLSVSTNNQPTTGNGLQASFVKTSDWGNGYVGVYRITNNGSSAVDGWTLGFDLPSNATISSWWDATQAKSGNRYTAGNLAWNRRIEVGQTREFGFSGSYSGAWVNPSNCTINGQACSGGTTSTNVALGRPVQVSSVETSALGGANATDGNNATRWASSYSDPQWIQVDLGSSKSLTKVVLNWEAAYARAYQVQVSDDASTWRTLSTVSNGDGGTDTLNITGSGRYVRIYATQRGTEWGYSLWEIAAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ1</accession>
    <name>A9AZQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4473</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4473"/>
    <dbReference type="EnsemblBacteria" id="ABX07105">
        <property type="protein sequence ID" value="ABX07105"/>
        <property type="gene ID" value="Haur_4473"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4473"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_433986_0_0_0"/>
    <dbReference type="OMA" id="YLGRNTD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4528-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="334"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="630" mass="69784" checksum="8B2212AF3A00C6AF" modified="2008-01-15" version="1">MQRFNPKRYFDLRNRLQSDQQRLWALFSTLIISLLLTTLVLRIAPPATETGRLIFRPVDSVTEDDRTQAEQPPPTLPPAIEPQNLVDASAILPRSAEAPTIIDDIRFTSEQNLTVANIQTLLDAQPGTLKAALVTVGDRNLSLAEVVVGQAYLYSLNPKLLLALLEFQQGLLTNPTPNPDQLDWAMKYQGEDEKWRGLHGQIRWAARELRRGVRDFAYVTELQYRDKDVKGPIPAGLNPSSYAVIRVLAQTMTPEELAKVLSDGSFVATYSKFFEDPRQTLGQVPAPATPFLRWPLRNVTYITSFFDHEYPFLTPNQSLVSWWGRRETELSYDGHDGWDYGARPPEAVVAAADGTVVWASNSDDGCGVPAKGVVLDHGNGYRTLYWHLSEISVELGQSIKGGEQLGIVGSTGCAIGPHLHFQTQYLGRNTDPYGWCSSEPDPWSSYPVGTASRWLWADRPNPCDLGQTIAVRPSDQGFSRSEGNWQNAPIGAGGETLWITSQIPITTTETLTDTMSDLAGVATPQPTPSQPPSTATWQTSIPSAGRYRVLTYIPYYYNGHDDAVAAHYVIEHAEGRSDVVVNQFVYANEWADLGTYTFDPSKPAKVELSNETSMADQGIWVGTTVWLPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV2</accession>
    <name>A9AZV2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4525"/>
    <dbReference type="ESTHER" id="hera2-a9azv2">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07156">
        <property type="protein sequence ID" value="ABX07156"/>
        <property type="gene ID" value="Haur_4525"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4525"/>
    <dbReference type="eggNOG" id="COG2819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039834_1_2_0"/>
    <dbReference type="OMA" id="YAICEYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4580-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="30694" checksum="55CBFF5C414D2DCE" modified="2008-01-15" version="1">MQSIELSDATGFLERYADMPIRGLLPRNVDVWLPANYHSSSEAFPVIYMHDGQNLFDPALAYIGVDWGIDEALENLIASQTINGAIVVGIWNSEQRIRDYLPAKPFYSASAAIQAQFETAVGGGPLSDEYLAWIVKTLKPQIDTRYRTHPEPEHTSIMGASMGGLISLYALVEYPQIFGNAGCVSTHWPIGASSLVAWLGKRLPKAGKHRIYFDFGTEDLDAEYEPYQIEMDGFMQAAGYIQGDNWLTQKFVGAGHSELAWRERAELPLAFLLGASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY0</accession>
    <name>A9AZY0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1039"/>
    <dbReference type="EnsemblBacteria" id="ABX03687">
        <property type="protein sequence ID" value="ABX03687"/>
        <property type="gene ID" value="Haur_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1039"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_17_2_0"/>
    <dbReference type="OMA" id="NQKDYVH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1056-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="130"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="37732" checksum="B8F37DEF9BE22015" modified="2008-01-15" version="1">MKIAIIGTGWGARVQVPAFRSAGLKIVGIAAQNYEKTQREAATLNVEAFEHWRDLLSSDADLISIVTPPGTHCEISVAALEAGKHVLCEKPTALNVLEAQTMLEAAQAHPEQLSLIDHELRFLPIFQMARALINDGAIGQIRHVNSSVIFSSRADPQRPWNWWSDKEQAGGAWGAIGSHQIDMLRWLCGDFSSIRASLHTFVTERPLDDQLLPVTSDDFATAQVRLANGGFASIMISGVAALNENDRMIIHGEHGAIKIEGARLWHAERDGEWQERTPAHTVAIPSEISGNFPVGTVYLGHALKAYSRGQLDALEQAATFSDGLLTQSLLDAAHRSDENDGGWITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B063</accession>
    <name>A9B063_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2534"/>
    <dbReference type="EnsemblBacteria" id="ABX05172">
        <property type="protein sequence ID" value="ABX05172"/>
        <property type="gene ID" value="Haur_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2534"/>
    <dbReference type="HOGENOM" id="CLU_1459428_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2562-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="21637" checksum="BF080FE8A5739672" modified="2008-01-15" version="1">MFDPRRARGTRRAKPRRPRRTRNRVIGYGLSQISYRIRELSMSLHIGLYGSHDTELIEAVQSVCTLLGGDLVLLDAVPADSEPKSVQVLIWYMGQHPIKLSIEQQQWLNIYILRQRRITKALVNDLVFDGTVIFEQYMIFPFDPEEFAMRIINGSLRRGYQLDYRLDYRLRTFADACEVRAKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B064</accession>
    <name>A9B064_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2535"/>
    <dbReference type="EnsemblBacteria" id="ABX05173">
        <property type="protein sequence ID" value="ABX05173"/>
        <property type="gene ID" value="Haur_2535"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2535"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789349_0_0_0"/>
    <dbReference type="OMA" id="LNVEREN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2563-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KdpD" evidence="4">
        <location>
            <begin position="11"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="3">
        <location>
            <begin position="228"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="38743" checksum="EE212070F09179D4" modified="2008-01-15" version="1">MRSDSASYRYGEHRIYLSLAPGIGCTRRLMADAQLLAAQGYDVGIAFNASSDYLCDFARGLRPLPLIYERQNNQRIEALDLATILNDPPQIIVLGNLAHQHGLSNQPIEPLQLVEQLRMAGIAVWSTIYAYNLTTIAPIYTRLTNITPSPIIPESALEQASELVLIDPEPTDIIRQLDEGILLAPPDAEQARQTALRLDVLNQLRAATHALLEIRRPLSDSAERPRWLVGIGFNPSAMYLLQRAADLAYGMGALLIGVHIRPPGGGSSGYRLAAREHLDYAEELCHEVVIIEEKDVAAAMLQVAHEQHATGIFIGRPVRSRWDELRGGSLLTKLINSDRDLDIFVLADAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H5</accession>
    <name>A9B0H5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4562"/>
    <dbReference type="EnsemblBacteria" id="ABX07193">
        <property type="protein sequence ID" value="ABX07193"/>
        <property type="gene ID" value="Haur_4562"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4562"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_0"/>
    <dbReference type="OMA" id="VDFGHTH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4617-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="44039" checksum="3D01017A0F40368E" modified="2008-01-15" version="1">MNRPSALTADLSLMRELNRALVLQLIRREGRISRADIAKHTKLSRSTVSSIINDLIDASLVTETGIGTSKGGRRPIILEFNYQANYIIGLDVSRNAVSAVITDLNARICSRRQISFNVNDGPTVGMPLIKQLISTMLTESPVGRGRISAIGVGVPGPLDFRNGRTIAPPVMPGWDNVPIREELSQTFRLPVSIDNDANLAAMAEYRWGAGQGAQNMVYLYMSSAGIGAGLIIDSHLFRGSIGSAGEVGHTTLSVENDESFGPINAGSLEALASQITVLRLAREQKLISADDDVHTLVRKAESSPEIQAILRRTAHYLGVAIASIINIFNPDRVVIGGVIPETSPLLIETIRATVARRALSIAVNNTSIVPGALGRNVAALGAAALATERLFAPPALERPATLGVHSNEVGSLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B124</accession>
    <name>A9B124_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2664"/>
    <dbReference type="EnsemblBacteria" id="ABX05302">
        <property type="protein sequence ID" value="ABX05302"/>
        <property type="gene ID" value="Haur_2664"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2664"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_758140_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2694-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731781" evidence="1">
        <location>
            <begin position="24"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="21"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="39834" checksum="7714516989C05190" modified="2008-01-15" version="1">MKKYLLMLIMVAGLLGIPATTLVAQTPTIAPTPSPSTVPVVDLTFGTSLQGRAITGTRFGNGPRKLFVVSNTHGGPEANTYQLALALLEHFRQNPQQVPADVSLYIIPTVNPDGLAIGTRFNSRSVDLNRNMDTNFDACPENDWNQTVEGAYGIVSDTGGAFVESELESQLVRDLVLDASAVVWVHSDGGDVFPAFCEHGPSIALAQAYAEASGYRYDRYWRNYMITGGMHDWAGALGIASITPELSTGELPDFDENLRAVQAVMGRSEELLPLVTTTVEVTTNITMPTLLWRYWRAHGGPDFFGLPISPVVEYQGRPTVFFAEQYLSLVPDGADRMQPALRGEGGLALWQAYLLDQQSTSYQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B128</accession>
    <name>A9B128_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="9" type="ordered locus">Haur_2668</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2668"/>
    <dbReference type="EnsemblBacteria" id="ABX05306">
        <property type="protein sequence ID" value="ABX05306"/>
        <property type="gene ID" value="Haur_2668"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2668"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_1_0_0"/>
    <dbReference type="OMA" id="NTRSTKP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="105" mass="12142" checksum="DAC854DD3BE61848" modified="2008-01-15" version="1">MKKNIHPKYYPNAKIVVNGEEVLITGSTKPELRLDVWSGNHPFYTGEQRILDTAGQVDRFMKRLQSSQEKQSDAQRRREARAQQAPKKRSLYDEVYGEESASTEE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B129</accession>
    <name>RL27_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmA</name>
        <name type="ordered locus">Haur_2669</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B129"/>
    <dbReference type="SMR" id="A9B129"/>
    <dbReference type="STRING" id="316274.Haur_2669"/>
    <dbReference type="EnsemblBacteria" id="ABX05307">
        <property type="protein sequence ID" value="ABX05307"/>
        <property type="gene ID" value="Haur_2669"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2669"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_4_0_0"/>
    <dbReference type="OMA" id="GKDHTLH"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000128760" description="50S ribosomal protein L27">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="88" mass="9594" checksum="5DFE3097B2A28012" modified="2008-01-15" version="1">MAHKKGVGSSRNGRDSKPQMRGIKRFGGELVQPGSIIVRQCGTKVRPGANVGLGRDYTIYSMIDGHVKFEDYSRTQKMVSVVPAEAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9B177</accession>
    <name>A9B177_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ordered locus">Haur_4633</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4633"/>
    <dbReference type="EnsemblBacteria" id="ABX07264">
        <property type="protein sequence ID" value="ABX07264"/>
        <property type="gene ID" value="Haur_4633"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4633"/>
    <dbReference type="eggNOG" id="COG0072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016891_0_0_0"/>
    <dbReference type="OMA" id="ISYNWLK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
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        <property type="entry name" value="pheT_bact"/>
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        <property type="entry name" value="TRBD"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
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        <location>
            <begin position="62"/>
            <end position="181"/>
        </location>
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    <feature type="domain" description="B5" evidence="18">
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            <begin position="433"/>
            <end position="512"/>
        </location>
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            <begin position="744"/>
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        </location>
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    <feature type="binding site" evidence="14">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="14">
        <location>
            <position position="499"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="14">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
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            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABX07264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="838" mass="92054" checksum="3DDC4DDA2A690274" modified="2008-01-15" version="1">MRVPLSWLREFVDITISPEELAERLTRAGLEVASIDYVGLQAPAGSAWAPDLSSATPPDYIPWDRETIFVGQIVDVQPHPNAERLKLPRIAYGEGRELTVVTGAPNIELGMSGQKVVLATKGARLLDGHSETRQWLTLKPTKLRGVPSEGMVCSEMELALSDEHDGIIFLPDDAPVGTPLADYWGDAVLEIETTPNYAHTLSILGVAREVAALTGAELRMPSFDLPTNGPAIADKIQVEIVDSNICPRFVAGLIEGVKIAPSPWWMQRRLRLAGQRPINNIADITNYVMLELGEPSHAFDADQVAQGRLIIRPAAAGEKLETLDHVVRELRPIDTVVADPNGPSSLAGVMGGAASEISDSTVNVLYEAALWNPIAIRRTAQHFKLFSEASKRFEKGVDPTLPPRTTIRGLNLIQQLAGGTIANGLVDVCPVPFARREIELALGEVKRILGIDLEQAEVANLLSRLGFECAVVESSRGPALHVLVPAHRTDVEIEADLLEDVARMYGYDRIPEALMADTLPTQRANPLFEATERLRDMLVAAGLDEAISYSLSNDSLQNSVYVSENGANAEQFVRLENPLTPERSVMRRSILPELLSIVVGDLRERERVALFEIGAVFHPVAGQLLPDEPRNLALILAGTRQPSTWSQPSPEGFDFFDLKGVIEEVLRRHGLRDRASFQVASDERLHPGRSAKIVVDEVVVGVFGELHPLVRDRFGFSVPRVCIAELSVDQLLKVSQPTKYTSISRFPATVQDLALVANDELAADLIAKTIKQYGGEFLEDVRLFDVYTGSPIPAGQRSLAFRLRFRAPDRTLADKDLLKTREKLLKQLERELGVQIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B185</accession>
    <name>A9B185_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4641"/>
    <dbReference type="EnsemblBacteria" id="ABX07272">
        <property type="protein sequence ID" value="ABX07272"/>
        <property type="gene ID" value="Haur_4641"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4641"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_384891_0_0_0"/>
    <dbReference type="OMA" id="CVETVIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4698-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="810" mass="82646" checksum="876A1AB51470079F" modified="2008-01-15" version="1">MKSFFRRQRPTSLRERGKGKVRWTIWELTALVVSIVMMATPLLAAISSAIFPFNAQAQATIRPTSAATPVTPLPPTATQTYPVPTETPLVTPCPTFEPTETPTETATTYPTPGTPGTPTDTPSVTDTPTTIITSTNTPAVTDTPSVTDTPSVTDTPSAPTATTIITPTETSVVSPTIPRGGMSGSTRLHRPLAQTPDPCATPPTIVIPPTDTIPPDETPTGTITGPVTLTPATPTIDCLVASCTPVPTLPTDIATATETTLPADEPIAVGKSSSRALVQPGETFSYIITVSFQDNGDGQTSRSVSISDPLPSQVTFIAVQQLGTATCVGGTTVNCNGTVSAGNPIVVTIQVQVNASVALGTNIVNIVSATAANRTLQASDTVIVPDTLPTSTLGTAGPSFTPIVVTNTPITPIVTNTPITPIGVTNTPPTSTPVTPIGATNTPGGSTSIPVTTGPSNTPRPNQPSNTPRPNQPSNTPRPNQPSNTPRPNQPSNTPQPNQPSNTPRPDITPVPATNVPVATVVPPSNPSATPRPGVPVPSATQRPGGGSNPSATPRPGAPVPSATNAPAGSQPTNAPAPATATPTNPAGFVTDPIVTGLQFQKKSDWGSRFAGESLIYTITIISPTNSLNAGTMRDVVVVDQLPSNLETNGPIKVSDQNARVEQQGNQITVRVGVLPAGQTLTIMIPVKIKDGVAAQTRIVNQAQLNFTGLAQPIYSNISSVLVVGEAPAVSATAVPKGNVGGGAATANPATVTPNTGIGGGQGSGDGTGATDVGVSNPATNMGIPAAGFVLFALTMFVHVIRVRREMTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A0</accession>
    <name>A9B1A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4656"/>
    <dbReference type="EnsemblBacteria" id="ABX07287">
        <property type="protein sequence ID" value="ABX07287"/>
        <property type="gene ID" value="Haur_4656"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4656"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388237_0_0_0"/>
    <dbReference type="OMA" id="GNAIFIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4713-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="333"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="455"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="677" mass="74168" checksum="99A165B001905834" modified="2008-01-15" version="1">MADVATTQNHARPISGFQLLAIAEAINNAANLSSLVATVAELCATGFGVEVVKLGLLDNEHHSGSSTPYLYGNPSKATQKLLDQAIAQTIEQKTALLPSNDESAQAQLLVLPLLASQQLIGFLALLLPKKGRWSAEAIEAAQLLAHNLALAISAVQLKDYTAKRNQEINTLNDIAATITSSLDPRQVYRLVVKKINEYFQVEAGSLLLLDPVTNELVFVMTLEAGEEKLAGVRVPPGQGLVGAAITTRQPVVVLDAQNDPRFYRRVSEDVGFVTRSVLCVPMLVKNREIGVIQLLNKLEGVFNTEDTQRLQAMANTVGVAIDNANLFHEVSQNRNRLQALLNSTTDGILMIDPDDVVLTANPMLGELFGWEWRNIIGEAGSDILARIKEQSRVVNELPNSETCEIEVLRPRTRYVRQEPLPVRNNFGNVIGTLIVFHDITEEYQLAQIREDYMGMLVHDLRAPLTAIINGMTMVRRGFAGPINDQQRELLDIANNSSQEMVGMINTLLDISKMEAGELVLNRAPCSAYEIVDRASERLINSARSVDISINLDMALNLPIIDADQDKIVRILQNLLDNAIKFTPVGGSVTIRVRQLTDNEKQTICWSVIDAGPGIPESYRAKIFDKFVQVAGQRKGTGLGLAFAKLASEAHGGRIWVESVEGEGSTFSFTIPYEPAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A5</accession>
    <name>A9B1A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4661"/>
    <dbReference type="EnsemblBacteria" id="ABX07292">
        <property type="protein sequence ID" value="ABX07292"/>
        <property type="gene ID" value="Haur_4661"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4661"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_16_0_0"/>
    <dbReference type="OMA" id="LWQMMLL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4718-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="454" mass="47857" checksum="2E533887821C05CA" modified="2008-01-15" version="1">MAEATRKQPSGMLAFSIMWFGQVVSLLGSSMSSFALTIWAWQITGQATALALVGFFSFAPSIIVSPFAGALVDRWNRKLVLILSDLATGLSTIAILLLYHNDVLQIWHLYVAGAFASIFQSFQWPAYSAAVSTMLPKQHYARASGMMSMAESAAGIVAPALAGFLLTVMGIGGILIIDIVTFVFAVSAVLFVNIPQPTQSEAGAQGKGSLWSEAGFGFRYILARPSLLGLQLTFFMINFVGSFEATMTAPMILARTDSNSAIMGTVQSAMGIGGVIGGLILSVWGGPKRKVHGVLGGMALSSFFGGILMGLGQNTLVWSIAGFGLLFVLPMLNGSNQAIWQAKVPPDIQGRVFAVRRMIAQISGPIAILIVGPLADKVFEPRMAVGGAWVDMFDSWVGSGKGAGIALIMVLSGIVGIAVAVIAYGVRVVRHAEDLIPDHQDSPSSSPELQAEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N8</accession>
    <name>A9B1N8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1275"/>
    <dbReference type="EnsemblBacteria" id="ABX03923">
        <property type="protein sequence ID" value="ABX03923"/>
        <property type="gene ID" value="Haur_1275"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1275"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_628174_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1297-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="436" mass="43698" checksum="1DB6C6435809FD63" modified="2008-01-15" version="1">MAAPIVQADFEVMDQVAQRLSKNAESVTAMQNTLKQTIEDLRSTWLGDAAVAFQKEMQADILPAVQRLINAFQTAQSTTLEIKKVLQEAEQEAANLFKGDPTGGSASTQSASSSAGGGGASSAGGDTAAASASPSNVGVMAGGTSSASASGSGGGGGGGGGAASAQASGGGGGGGGGAASAQPTGQQPKATSGGGGGGGGGGGTASAQPTGGNAAAAGNASLGKLSEKYETGGRGPGTVSSGKGDLGGASYGSYQMTSQTAIKKDGKIVFVNGGRVAEFLRNPAGAQYAEEFKGLKPGSAEFTAKWKQIAARDPQGFAAAQHQYIENTHYQPQVNKLKAAGFDVNNYSPAMRDVVWSTSVQHGPGASVITNALRGKDLSQMSESQIINAIYTERSKTLDNGRLAYFKNTSDAGVIQGLKNRFVNERKDALNMSANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T3</accession>
    <name>A9B1T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2737"/>
    <dbReference type="EnsemblBacteria" id="ABX05375">
        <property type="protein sequence ID" value="ABX05375"/>
        <property type="gene ID" value="Haur_2737"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2737"/>
    <dbReference type="HOGENOM" id="CLU_1233655_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2768-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24614" checksum="2A2E289BD1E9CFC0" modified="2008-01-15" version="1">MADPTKPPYHDQQSPTAYAIPGYVVPTAFDPSINQPNRWINWMMINILSFIVAIVTFAVLVFIAITTIGKLSDLLMSLLLNLNTLRIQILGLLILGLIAAITGAVSALTQRSALNYQVPRWPWVIKTALAVGMLFPVSTVLSNLVGDTFFLRDTSWQRYITTMLVNFGPTAFGTALIQAFEVKKVANNPIEWVWVRGFTWTILGSLVVGSIISFVMGVIGSISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1U5</accession>
    <name>A9B1U5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2749"/>
    <dbReference type="EnsemblBacteria" id="ABX05387">
        <property type="protein sequence ID" value="ABX05387"/>
        <property type="gene ID" value="Haur_2749"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2749"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1756334_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2780-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="17105" checksum="5E0A2D5BC99418B2" modified="2008-01-15" version="1">MLANVCLVESTRVLQIMAKTQFRGAEQLLTQFNLSTTIAICSTSFQLLQWLEYQPQQYARLILVDQRLADGVSIDELMPQIRSEHFKHRALADDAKIIGWSRDDQAQEVFYRAGLDGFISKNRQSHQLIRDIVTVFTNQAEHPWLQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1V6</accession>
    <name>A9B1V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2760"/>
    <dbReference type="EnsemblBacteria" id="ABX05398">
        <property type="protein sequence ID" value="ABX05398"/>
        <property type="gene ID" value="Haur_2760"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2760"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_2_0"/>
    <dbReference type="OMA" id="QPTKWDG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2791-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735191" evidence="2">
        <location>
            <begin position="22"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="50"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="4">
        <location>
            <begin position="50"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="29915" checksum="D032409EC4E82CF1" modified="2008-01-15" version="1">MKRLNVVALLSLLLVVLGACGAESATPTTAPTTASTTAPVAGKIDLAGREVSIAVENLYPPFNYINPQTGKGEGWDYDAWTAICAELNCKPVFKETSWEGMIQAVGNGQFDAAADGITITPERAEQVAFSDGYIQISQRLLVRNDETRFTSMDEFAKTEFRLGTQTGTSNYETAKGLLDEARIQGFETFPFAVAALINGDVDAVIMDETAGQGYVGNNSDQLKLVGDPIKSDQLGFIFPKNSDLVEPVNAALKALRENGKLAELEKKYFGPDFKLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y3</accession>
    <name>A9B1Y3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2787"/>
    <dbReference type="EnsemblBacteria" id="ABX05425">
        <property type="protein sequence ID" value="ABX05425"/>
        <property type="gene ID" value="Haur_2787"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2787"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_2_0"/>
    <dbReference type="OMA" id="LRWHPGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2818-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="74"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="30201" checksum="5DB76D1395107BC7" modified="2008-01-15" version="1">MALAIEQPTTAPRSAKKRLQLRQLGQRWLPWLVPIVLIGVWQLAATIGWLSARVLPAPSTILQTTWELLLHQNLLGDIAVSTRRALLGLAIGGSLGFIFGLLNGTFPTSERLFDSTFQMIRNIPHLALLPLVILWFGIGETSRLFLVAFGVFFPLYLNTYHGVRSIDPNLREMGIVYGLSKWGLFRHIIFPGALPSILVGLRFALGVMWLTLIVAESLASNAGIGHLTMNAREFMQTDVLVMGIVIYALLGKLADTIARLIERRSLRWRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z4</accession>
    <name>A9B1Z4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2798"/>
    <dbReference type="EnsemblBacteria" id="ABX05436">
        <property type="protein sequence ID" value="ABX05436"/>
        <property type="gene ID" value="Haur_2798"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2798"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_0"/>
    <dbReference type="OMA" id="FIARQIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2829-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="191"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="253"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="490" mass="53960" checksum="C4064B6404BB45DF" modified="2008-01-15" version="1">MTLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPLERYFSGTSVSLLPVPNEDFEGSPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEKNSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTVDRALDTLSLVFLIAGSLTVVLMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARMEGLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRLVNDLLFLAQTEAGVQMRSEPVELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRLKQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTGEGIPPDILPNIFQRFYRADKSRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRESPSQPLPIVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B236</accession>
    <name>A9B236_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4755"/>
    <dbReference type="EnsemblBacteria" id="ABX07386">
        <property type="protein sequence ID" value="ABX07386"/>
        <property type="gene ID" value="Haur_4755"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4755"/>
    <dbReference type="HOGENOM" id="CLU_1394678_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4813-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="22165" checksum="E0E394102DA7288A" modified="2008-01-15" version="1">MTRQQYLLTIRPRYWGANLVFLVLASGVIINAMIQALTTPNVDFSPALLVFVGWIVWAARGLNQFIRVTEQSLIIKHSGKPVTIDWVHVAGVGTLQGGMGIAMPYLILRQPYANLPEPNLRRFASANLRDEIVIINPLHWNKITKLWPLILHHVPATNEYQVPFDFNATPKIERRIIGVFVGISFLAILLLYWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B240</accession>
    <name>A9B240_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4759"/>
    <dbReference type="EnsemblBacteria" id="ABX07390">
        <property type="protein sequence ID" value="ABX07390"/>
        <property type="gene ID" value="Haur_4759"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4759"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882449_0_0_0"/>
    <dbReference type="OMA" id="CRTAVCA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4817-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735403" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="155"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="31548" checksum="84AA9E296EE5A98F" modified="2008-01-15" version="1">MQRWWRVFYGVIIVGLVGCGAATPTATPVAKSRVQAVLAASNLVVGPNRLPIGLIVDGSPINDPNVQVKLRLYYLDGTDAEKTQVAGEGSADYFGQGLPAGIYVTYPDFKKAGDWGVEVEATLPGKEPTVSTLRLSVLAQDPTPAIGSKAIAVDTPTVKTAPDLSQISSDPNPNPALYQLSIADAITSGKPTAILFGTPGFCKTATCGPSVTVLGNLQKTYGEKMNFIHVEVYKFPFSESVQANPPLLVPAMAEWRLQSEPWLFLLGKDGTIVNKYEGGITTEELGPMIDTILAQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C6</accession>
    <name>A9B2C6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03971">
        <property type="protein sequence ID" value="ABX03971"/>
        <property type="gene ID" value="Haur_1326"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1326"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1480115_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1347-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4" evidence="1">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="21438" checksum="A5077358C8958D26" modified="2008-01-15" version="1">MTNESIPPNSSSSIGSLDGRLAEALVQKRLFLFFLKKTGCSVDAEDLRSITGMKILQRMQNEAKPLVFHSKFQQYKFIWVTARRVLSTYFRNKAIRDRKEPRYDEYSKQYHENTMINPIEEALSMLHIVEYLHDLTDKERYIFIQRLVHELTFKEIGLKLGISEDNVRMTFNRSIAKIKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C7</accession>
    <name>A9B2C7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03972">
        <property type="protein sequence ID" value="ABX03972"/>
        <property type="gene ID" value="Haur_1327"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1327"/>
    <dbReference type="HOGENOM" id="CLU_1945812_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1348-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="14271" checksum="5A3A28A66725CC84" modified="2008-01-15" version="1">MNLETGMFYNTMIKTLKALLRQLFPDINWSIADYETVIKRGFIDAFGHPNGIVITGSLPNRPKQTVHISNLVLYDATPMSEDMAITASMVGARMRILLKDDSSLPIPAHTPAQKAHLGISQVRFGLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E5</accession>
    <name>A9B2E5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1345"/>
    <dbReference type="EnsemblBacteria" id="ABX03990">
        <property type="protein sequence ID" value="ABX03990"/>
        <property type="gene ID" value="Haur_1345"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1345"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="HNELALN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1366-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13416" checksum="8C39F02ABEF2F17A" modified="2008-01-15" version="1">MQPTIVIVEDDHSIVAVLEEFLADEGYAVISLTSVGALMAYFAQQIPQLILTDVNLPDGDGGTIGSLLASNEATRGIPIIVMSGHNELALNLDHHAGSFLAKPFDLGHLLLMIQQLLRVSNDNAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F4</accession>
    <name>A9B2F4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1354"/>
    <dbReference type="EnsemblBacteria" id="ABX03999">
        <property type="protein sequence ID" value="ABX03999"/>
        <property type="gene ID" value="Haur_1354"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1354"/>
    <dbReference type="HOGENOM" id="CLU_2569162_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1375-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="8923" checksum="9BF64AA981A4B00F" modified="2008-01-15" version="1">MVLFGLGAPMDQLNKHGRWYCSTCCHVATTVSDYKAHKATHAMIGEQHDPTAQPASLIELPIVRVWQHATRLTVVKQKGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G9</accession>
    <name>A9B2G9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phage tail tape measure protein, TP901 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1369"/>
    <dbReference type="EnsemblBacteria" id="ABX04014">
        <property type="protein sequence ID" value="ABX04014"/>
        <property type="gene ID" value="Haur_1369"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1369"/>
    <dbReference type="eggNOG" id="COG4372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_257929_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1390-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="858"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="883"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="PhageMin_Tail" evidence="4">
        <location>
            <begin position="105"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="632"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1347" mass="142843" checksum="6FDF8D99BF999DF9" modified="2008-01-15" version="1">MADEELGRAIIKIGADDAELDRSISNAETKAKGFAQSLAESLSTALTTAIAGAVAAAGAALAGLAVTGVNAFAGFQEQMNSVFTLLPGISQQAMQQMGEQVKDFAVEFGALPEKVIPALYEALSSGVPKDNVFSFLETAQKAAIGGVTDTQTTVDGLTSVVNAYGADVLSVQDASDQMFTAVAYGKTTFAELASTLYNVNPIAASLGVSFSDVSAAIAAMTSQGVPTAQTTTMLRQLFVELSQSGGEVSDLFQQLSGTSFKSFIESGGNVQQALQLLEQHANASGVGINDLFSSVEAGSAALTLTGRGTEMFTGALDAMQNSAGATEAAYTQMDQGLARAFDGIRAQFAVLQTNIGNALAPTVQAFADWLAEAMPRISAVVVGAFERIGAAVQMVGPYFLDFASTASEAFGLFIDLASSAVQWGSNIATQLANGIMGGAGAVVDSLGYIGDLITYWLEPHSPPKLLPNIDTWGRDTAQVWMDGWNDARLPTDGLLAYLETELKSIEDAQQRVKEAAQEQQLLALINSTGGKDSDREQAKLELAALKLRQKIREEQAKAAEQETKKPKASGGGGGGGKSPMDDAAKNAEAAARAQWEYTFSIAGTVDRLQMLKDKQAAYATTDAEYWRLQGQINQEEQKRQAELNKLAKEQRDYELSLMSTEDQLARLRQEQGQYAEGSAEYNDIQQEINKAEKQRQRELEEVKRKQDEAAKAERDYQYATADTAGKLAILQGELANTNADQSEYWRIKTQILQLEAQQQKELEASAEKMKGVGGAAKGAAKGVGALVPPFTKVKDGADETNQSMQDAATGAEAAADRYADLKDRQVEMATATAPVPSLIDRIRNAFSQAAPFIESVKGAFMGIAALFTGMGLVSLFSGLAGAVAALVSPMGLLVAGAAALGLAWQTNFATIRTITTEVFTSIQSMVQTAWGIITSWFRENGEQIVTFLRNAWGRIEGIVSTVLGAVGTVIQTALGAIRTFLEQHGEEIKGVLTMAWETIQVVIDGALDVINGAIIPFFHGIATFLSDHKDQITGLLSGAWSIIKGIVEAAMSVIQGVIKTVSAVIQGDWSGAWTAIKDVFAGLWNGIIDIVKGALEVVWNLLVVAWDLIGTGISTAWDGISDYFRTMFGGVLDNLDGFLEQFKNGVAVAWQWIKDASAAVWDEITNGIVEAFRGILSGIKSPLNLMITAVNKLIEGANTVGSALGFGGIPLIPYLADGVKNWAGGLAFASEPWKGIEAMRTRGGDFALLPPGISNIPRGAEVFTAEETKGMAARMVVPQGGMVGTLSNALPTNQPSAPSIINQITIDARQATNPAAIKAAVEEVWNKKMKDILGSANILLKTNPYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2I3</accession>
    <name>A9B2I3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1383"/>
    <dbReference type="EnsemblBacteria" id="ABX04028">
        <property type="protein sequence ID" value="ABX04028"/>
        <property type="gene ID" value="Haur_1383"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1383"/>
    <dbReference type="eggNOG" id="ENOG5033Z51">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520510_0_0_0"/>
    <dbReference type="OMA" id="RRREYLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1404-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="57462" checksum="385287D4A6172480" modified="2008-01-15" version="1">MPTAFDNLSVEVAKKRLPTTPEAVKSAVLFRDGDHWQGGAAWTGPAPASTDKGATEVMTRIQREFVSSNVIAEVIERHANAVCGREPQWSYAVRRPLLEEEQPNPQEQGLLDEAEAAMTSWWDQRNVLGILQESIATAVVHGRAVLRLFVPPAYVEDNVIQVQETLADALNLIWLDWLAPEQAGVSRDKATMQACGVYVYTNDNKKEVAEVTFIDEGQTVMRTLEGEAMTGETRLPLMGHLLMIEIVCKPLIGLSMQQMQKALNMTLTMLQHNIVISGFVERVMTNAQMPFDEVDDPANPGKKLRVYRPYDIGPGKTTNLIGLPMREKDGQIERITGYTTPSVQWREPVPVGTFIDTDAAIYSRMLKECKQLHALLSGDAVASGESRKQALLDFAMSLGPTATALKQLVRWVLEAALALAAHFAGRAQAFDSLRADVTPRLWLGSLSSEERNFLLAAYEKGAISHDLFLSLIDVEDVDAEKARIAAEQEEKQARSARSLGAALAMQQARLDSGAASTGLEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B384</accession>
    <name>A9B384_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1402"/>
    <dbReference type="EnsemblBacteria" id="ABX04047">
        <property type="protein sequence ID" value="ABX04047"/>
        <property type="gene ID" value="Haur_1402"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1402"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064891_2_1_0"/>
    <dbReference type="OMA" id="ATMRSKT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1423-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="10"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="35294" checksum="1E8BC048B513650F" modified="2008-01-15" version="1">MFQRATKFRSKLRLALLGVAGSGKTYTALNIAKHLGRNIAVIDTEHGSASKYADDVASFDVVELTSFHPKRYIEAIKAANWVNYDVLIIDSLSHAWNGKDGILEQVDQVGKRGANKFTAWADATPLHQQLIDAILDCRMHVICTMRLKTEYVVEQNERGKQTPRKVGLAPVQRDGLEYEFDVVADLDMHNTLMVSKTRCPALHGVSIPRAGAEIATTLLDWLNQGIDLHALNEPDPASIDPLNNPTPSLYKIERVQACRGCRASVIWIDNQPYNADANGQRTPQLHWETCPKAHLFRQTNRLTAAQMAERDAVFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B390</accession>
    <name>A9B390_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YtkA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1409"/>
    <dbReference type="EnsemblBacteria" id="ABX04053">
        <property type="protein sequence ID" value="ABX04053"/>
        <property type="gene ID" value="Haur_1409"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1409"/>
    <dbReference type="eggNOG" id="ENOG5030SMT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153190_0_0_0"/>
    <dbReference type="OMA" id="MEGDWRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1431-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032693">
        <property type="entry name" value="YtkA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13115">
        <property type="entry name" value="YtkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734527" description="YtkA domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="YtkA" evidence="2">
        <location>
            <begin position="32"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14221" checksum="19341AA9E63B0C77" modified="2008-01-15" version="1">MFKRLLFCLLLLTSLVACGGNGAGQVPAPVEKTVDGVTLKLISESPLSQNTDQTWVINVTQNGQPVDNADVYLDIDMPSMPMGQNKPLAKGEGNGNYRAQGIYTMGGAWAVSVFAEFDGKEYQASFDFNVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B391</accession>
    <name>A9B391_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1410"/>
    <dbReference type="EnsemblBacteria" id="ABX04054">
        <property type="protein sequence ID" value="ABX04054"/>
        <property type="gene ID" value="Haur_1410"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1410"/>
    <dbReference type="HOGENOM" id="CLU_1882892_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1432-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15129" checksum="80C5F5CBAAC7B2DE" modified="2008-01-15" version="1">MWIGMQTAQISSINLSIQQRWLIWLWVLFCGLNPLSCLWHCGASTQANEMNLNRDAGMFICLMAESQPPASSLHTHAPSSNPDPAQQGVAQLNGLENLELDLNWLWQQSNYQPLIWQSQPTAPPLAPPPELLRLS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C5</accession>
    <name>PYRF_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="1">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">OMP decarboxylase</fullName>
            <shortName evidence="1">OMPDCase</shortName>
            <shortName evidence="1">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrF</name>
        <name type="ordered locus">Haur_1444</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B3C5"/>
    <dbReference type="SMR" id="A9B3C5"/>
    <dbReference type="STRING" id="316274.Haur_1444"/>
    <dbReference type="EnsemblBacteria" id="ABX04088">
        <property type="protein sequence ID" value="ABX04088"/>
        <property type="gene ID" value="Haur_1444"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1444"/>
    <dbReference type="eggNOG" id="COG0284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060704_1_0_0"/>
    <dbReference type="OMA" id="QSAFFER"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01215">
        <property type="entry name" value="OMPdecase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000164750" description="Orotidine 5'-phosphate decarboxylase">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01215"/>
        </source>
    </evidence>
    <sequence length="267" mass="28515" checksum="860B9A7E7AE8DBB9" modified="2008-01-15" version="1">MFMQKFRAAATSNRSTLCIGLDPDLARLPEHLPRDAAGIVQFNQAIIEATSDLVCAYKPNMAFYEALGSAGWLALKQTIASIPSHIPVLLDAKRGDIGSTAQAYASAAFDELGVDAITLSPYMGYDSLQPFLERADKTCFILCRTSNPGGDDVQNLLLDNGEPLFLKIAELVAKRWNSNHNCGLVVGATYPAEIATIHQRYPELPLLVPGVGSQGGDIEEVLAAAGEQAIINVSRSVLYASGGSSFAEAARKVAQAFLVPKQALNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q9</accession>
    <name>A9B3Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2993"/>
    <dbReference type="EnsemblBacteria" id="ABX05631">
        <property type="protein sequence ID" value="ABX05631"/>
        <property type="gene ID" value="Haur_2993"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2993"/>
    <dbReference type="eggNOG" id="COG1748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065104_1_0_0"/>
    <dbReference type="OMA" id="GVWFPEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3025-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="38962" checksum="35C8AC5251EAF436" modified="2008-01-15" version="1">MQAIVILGGYGVVGSQIAQILRQSHPDLPLILAGRNPQQAQQLVAELGGPTSAAAIDVLKPQPLAGLQPQAIINAVNDPHDYVLQEAVARGIPMVDITRWTSRLQQTLDRIDRNTLKAPLLFASHWMAGLASVVAFAATQQLAQTEQMDLHVLFSLKDKAGPNSIEYMEHIATPFTITEKHQPREVYPYTEPQTVTFPNGYRAKTYRFDTPDQWTLPQSTKAASVSARITFDDRLTMGLLLGLARSGVWKLLMHRRFDRLRHALLYNPGTGAAHELVWQISGRDHAGKAQQLTKTIVDRQGQTHLTAVGAVIQLETMLGLDGSQAFAPGIYFPETAPKLAYALGRMQQLGVELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3V9</accession>
    <name>A9B3V9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3459"/>
    <dbReference type="EnsemblBacteria" id="ABX06095">
        <property type="protein sequence ID" value="ABX06095"/>
        <property type="gene ID" value="Haur_3459"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3459"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_72_0"/>
    <dbReference type="OMA" id="MVDDRPE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3496-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="321"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="544" mass="59844" checksum="D932BE0E2C40F7DD" modified="2008-01-15" version="1">MASGQETILVIDDSEAIRVKLQAQLRSLGYQVVLAETGRNGLNAITQHHPHLILLDYQLPDTTGLDLLRKLRTDGNTVPILLMTAEGSERIAVTAFKMGVRDYLIKPFEPQDVAQAIDRALREWRLQREKEILLGQLQGQVRQLTVLHRVGKAVTAQLDASNLLERIVEASVFLSNADEGFVQLIDDNQLVVRASHNINPLHLRELSKHTDYELATRTIKTNKPIRINSERDGIRVQANYLAQAVLMVPLLVGTEALGVLTVAATTHRRNFDEGDERLMQMLADYASIALHNARTYSALRETQGRLVEAEKLSGMGRMAASLAHEINNPLAIIRSGLELVAQQHTPGTALGDLVQGLDEEVARIARLLYTLVNFYQPNNDGVPPDLNHLIISLMHITKPQLDKANVKLYQELATDLPAPNISSDACKQVLINLVRNAIDAMPDGGKLTIRTAHQKGQIFVNVEDSGIGIPPEHRERIFEPFFSTKGVTGTGLGLSVVYGILQQVGGAISVESIVDKGSNFTLRIPVAAQRSQSPDLDSDELLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B407</accession>
    <name>A9B407_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">murB</name>
        <name evidence="18" type="ordered locus">Haur_3507</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3507"/>
    <dbReference type="EnsemblBacteria" id="ABX06143">
        <property type="protein sequence ID" value="ABX06143"/>
        <property type="gene ID" value="Haur_3507"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3507"/>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035304_1_1_0"/>
    <dbReference type="OMA" id="MQNIGAY"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABX06143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="302" mass="32810" checksum="5785941EFC061348" modified="2008-01-15" version="1">MIDLREHELLAPYTAWRIGGPARYFVNVTSPEQQVEAVQWAELRQLPIFMLGGGSNLLMSDAGWNGLVIRNRATGFELHEHGDQLTIHVQAGAPTAGTVRRLAAQGIAGLEWAEGLPGTIGGAIYGNAGCYGGETVKHLQSARLLMPDNQIVEWAAADFQFDYRTSQLKRLAGNRPTTRIPYVLDAVLTAWRDDPVWIASKMAEIAEGRKQRTPAGSSCGSVFKNPANTTAGRLIDAAGLKGFRMGAAQIAEKHANYILNLGGATANDILRVAEYAQTEVLKQFGIELELEVRVITSEDQSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B414</accession>
    <name>RL23_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplW</name>
        <name type="ordered locus">Haur_4917</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B414"/>
    <dbReference type="SMR" id="A9B414"/>
    <dbReference type="STRING" id="316274.Haur_4917"/>
    <dbReference type="EnsemblBacteria" id="ABX07547">
        <property type="protein sequence ID" value="ABX07547"/>
        <property type="gene ID" value="Haur_4917"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4917"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_3_2_0"/>
    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144576" description="50S ribosomal protein L23">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <sequence length="98" mass="11117" checksum="B595240248BA2413" modified="2008-01-15" version="1">MNAHDIIIRPVITEKNTALMEEGKYTFEVAQEANKPMIKAAVQQIFNVNVKAVNTMNVKGKLKVRRTRNGQQSGYSRSWKKAIVTLAPGERIEIFEDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-25" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B416</accession>
    <name>RS19_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsS</name>
        <name type="ordered locus">Haur_4919</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ABX07549" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07549.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B416"/>
    <dbReference type="SMR" id="A9B416"/>
    <dbReference type="STRING" id="316274.Haur_4919"/>
    <dbReference type="EnsemblBacteria" id="ABX07549">
        <property type="protein sequence ID" value="ABX07549"/>
        <property type="gene ID" value="Haur_4919"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4919"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_0"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000354292" description="30S ribosomal protein S19">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="95" mass="10826" checksum="BA5D904930AFD518" modified="2008-11-25" version="2">MSRSTKKGPFVDVRLLSRVETMNRGNEKRPLKTWSRDSTIFPQMVGHTIAVHDGRRHVPVYITENMVGHKLGEFAPTRTFRGHGGKKADKRGKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A4</accession>
    <name>A9B4A4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0009"/>
    <dbReference type="EnsemblBacteria" id="ABX02661">
        <property type="protein sequence ID" value="ABX02661"/>
        <property type="gene ID" value="Haur_0009"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0009"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-9-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="71"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="161" mass="17495" checksum="2A6BCAB4C13D0FE0" modified="2008-01-15" version="1">MTTLLEQTQQLLARMDEREQQLALTLIKRIGKHQAHGAGFTWSLGVVYEDVQPGFSRCSLQIDPGHYNPAGIAHGGVAYSLLDTAMGGAFWTALERPLGCATLELKINYLRPIVAGTIIATAELVERTTRFGILTGRVVNEAGELLALGQGTFAIINYPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B1</accession>
    <name>A9B4B1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02668">
        <property type="protein sequence ID" value="ABX02668"/>
        <property type="gene ID" value="Haur_0016"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0016"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045644_1_2_0"/>
    <dbReference type="OMA" id="ADHAREY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-16-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="36679" checksum="83A8F041222F8A29" modified="2008-01-15" version="1">MDIGIWPWVGFTIFVFAMLALDLGVFHRNSHEVSVKEAAIWSVVWISLALTFNVGLYFWQGGDVALKFLTGYLIEKSLSVDNIFVFVLIFSYFQVPAKYQHRVLFWGVFGALVMRAILIFVGAALIERFEWIIYVFGAFLIYTGLKMFRQGETHLDPDNNPVVKLVRKVLPVTSEYHGEHFFTRHAGKLMATPLFLVLVLVEASDLIFAVDSIPAIFAVTTDTFLVYTSNVFAILGLRSLYFVLAGVVDKFYYLKYGLAVILTFVGSKMLIIALGYHVPTPVSLAVIIGVLAVAVIASLRRAKRLEGVDTPLDNPVTNKPVIKPDSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C9</accession>
    <name>A9B4C9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0034"/>
    <dbReference type="EnsemblBacteria" id="ABX02686">
        <property type="protein sequence ID" value="ABX02686"/>
        <property type="gene ID" value="Haur_0034"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0034"/>
    <dbReference type="eggNOG" id="COG2968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1249208_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-34-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="24203" checksum="5B1BB6638666C44E" modified="2008-01-15" version="1">MEPNLLNVSSSYRQLIDANRAEITVRIKGSSVISNNTALEKAKEVRQLVEALTSYGLDKTAIQLQSVVAEVNNGVLLRSSSATYSLLIRCTDLEQLPDVLGIITSQKQANLEHVTWGFPDDPAILNGWLQAALELAKAKAKAMAQTLGVRIIGVHRVDDQYGSEHHPYAQDGEFRKSASFMRSGGSGISKDDLGLAMIHRKQIEVNVQVAFIISPDENFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I1</accession>
    <name>A9B4I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1502"/>
    <dbReference type="EnsemblBacteria" id="ABX04146">
        <property type="protein sequence ID" value="ABX04146"/>
        <property type="gene ID" value="Haur_1502"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1502"/>
    <dbReference type="eggNOG" id="COG0633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_492377_0_0_0"/>
    <dbReference type="OMA" id="HASVCGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1524-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="3">
        <location>
            <begin position="252"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="368"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="561" mass="62153" checksum="547C00EBF12701F2" modified="2008-01-15" version="1">MARSFQALIPRLRLHAGLTLLLYVTTHLLNHAWGIFGLAALESSRRVFLSFWRHPAVFWVVPASLLIHVLLVSYKLLTITSWRRLHWNEWLQIGLGLIMPLLITSHIYATRFATILYGIRDTYSYVLLSQATIAVDLYLMLVVVWLHGNLGLMAYLWHKPWFARIKQPLLIAQIVIPLLALVGIVVAHREVNQLKQDPQWLEQVWQFANPQNIDVAAATAEFMGWFGSGYLALLLGLGGGRAIILRLRRKHYLISVEYKGIATVTIAPGTSLLEASLANGIPHAHSCGGRGRCSTCRIEIIEGVKALNPPTETELRLLKRFGASGDIRLACQTIPTAACVVRPLLHHHDRSLPGAPTMISHGADKQIVIMFADLRGFTTLSEGKLPYDTVFILNQYFQSMGQVIEANGGYLDKFIGDGIMALFGLDGTLEQACHNALAAAQAMAYQLDVLNQRLEHDVNEPLRMGIGIHCGHVIVGDLGYKRAKHLTAIGDAVNIAARLEEATKTLQTQLVVSRAVMQHSALDLHNLALSEIPIRGRTQPLEIYSIESAKSLVLVPLTLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4K3</accession>
    <name>A9B4K3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional antiterminator, BglG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1524"/>
    <dbReference type="EnsemblBacteria" id="ABX04168">
        <property type="protein sequence ID" value="ABX04168"/>
        <property type="gene ID" value="Haur_1524"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1524"/>
    <dbReference type="eggNOG" id="COG3711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_530775_0_0_0"/>
    <dbReference type="OMA" id="YMTAREQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1548-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007737">
        <property type="entry name" value="Mga_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011608">
        <property type="entry name" value="PRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05043">
        <property type="entry name" value="Mga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRD" evidence="5">
        <location>
            <begin position="317"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="4">
        <location>
            <begin position="429"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="513" mass="57096" checksum="C4262180762125A5" modified="2008-01-15" version="1">MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVPGVGMQLICSAQQRERLYAELESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLAVARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELAKRQALAALLWGDVPFSLPIISVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLLALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVALQLVCAARERPWPNQHETDHVTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPACNRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATIGVALPIDARDELILLLRAAVVRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVITTAPLALASVPIDVIQVHPMLHPEDIAALTQWMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q2</accession>
    <name>A9B4Q2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1574"/>
    <dbReference type="EnsemblBacteria" id="ABX04217">
        <property type="protein sequence ID" value="ABX04217"/>
        <property type="gene ID" value="Haur_1574"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1574"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_12_0"/>
    <dbReference type="OMA" id="AEACNFQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1598-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="530"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1596"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1714" mass="192081" checksum="F0417943FBD9ECFF" modified="2008-01-15" version="1">MRIQGATQSNPTDTSPDDDQPWCIHELVAQQSRYWADAVAVIHADTQLTYAQLDQRANQVAHALLEQGIKPDHLVALCLERSIDMLIIVFGILKAGAAYLPIDPHYPYERQRFMIEHSQAPLVITTAPLEGALASRPVEIQLELLMAIAAQKPTSAPNQRVDPDQLAYVIYTSGSSGQPKGVMITHRALVNHMQWMQTTFGFNRHDRFLQKTPLSFDASVWECYAPLLCGGQLILAKPDGHHDAHYLVEMIQRYQISVLQVVPSLLRMLQTEPQLANCRSLRYLFIGGEPLHSELVAQVRRVLPARMINLYGPTEATIDATWAECNQTTEYPTIPIGYPIDNLTTWVLDAQMQPVAVGRSGELYIGGMGLARGYQRQPDRSAERFVPDPFSTQPGTRLYKTGDRVRLLANGALLFLDRIDQQIKLRGYRIELGEIQAGLERHPQIRQSVVVGQLDQTKTLQLVAYVVPMPEARIPIEQLRALLKAQLPRYMLPSAFVILERLPLLANGKLDRASLPLPAPSAYQSSVIVPPRTPQEMHLLQQWQELLGFDQISIDDDFFDLGGHSLLATQLVARMRDQFQRDWSVATIFNYPTIEQLAAQLRSTPDHQHVATIPVADRQQRIPLSTMQERVWFLTQLNPESRAYHFQMTIHFTGQLHVPILEQACSEIVRRHEILRTTFPTEAGQPYQQIHAPWAVTIPSIDLRQYPLEQASHLAEQAIAVAMCEAFDLTQLPLVRWSVFRLADDQWMLLQIEHHFIHDGWSIARLLAEIKTLYTDYLAGLAPSLPALPIQYADFAVWQRQQLNAGLLERDLRYWEAQLAHRPVVLELPTDYQRPPVQSMRGSAERIAIPAELANAARELSRRVGTTLFMTLLTTFSTLLYRYTEQTDILLGSGIANRRQRELEPLLGMFVNTVVLRTDLQGNPSFRELLLRTRSLMLEQYEHLDVLIEKVVERLRLPRDLSRNPLFQVMFSFHDSPVPTLDLPMLHGEILERNNGSAKADLNVIVIPYAEQHGAAGHSAEQKAITMIWEYSTDLFTQATIQTMIGHFQALLRSVTQNPDQRINQLAMLSRAETAQCLEQARGPLVPTPTTTLHGLFANYVREQPNALAIVTDHESISYSRLNQRADMLAGALRQAGVGPGMEVGIVSEPSIATIAGILAVLKLGAAYVPLDPSHPQQRLNLIINEAQLQAILVESQLEQLLPNTSAAIIRLDSDHGAVTDYPIVAAQACAYGLFTSGSTGQPKGVACSHEAVINLLDAMQQMRPLPQGCRHSLWTSLSFDVSVYEIFSALTQGGTLYLIDQTMRLDADQFFAWLAKYAIESAYIPPFMLHDLALWLMANRNRLQLKRLLVGVEPIPEQNLAIIGQLIPGLTIINGYGPTETTICATFYSVPPFNDSARVTPIGRAIQQMAVYVLDRELQPMPTGVIGDIYIAGIGLALGYIAKPDLTAEVFLPNPLSAEPGMRMYRSGDRGRYLADGSLMFVGRSDRQVKIRGMRIELNEIRTCVLQHAQVHEAVVNIYNDQPDNPQIVAYVVPTKGQLLTEASLRTYIGQKLPLAMQPQAFVLLDRLPLTANDKLDWAALPAPFPATRLSPMEAPSTPLEQILAGIWSELFAQPAISIDANFFELGGHSLLATRVASRLQETLHKTIPVSLFFQYPTIKQLAHVLDGYTAYESDHHRAMLPESDRSLLSRVHELSEQEVDQLLAQFLDESVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R5</accession>
    <name>A9B4R5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_1587</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1587"/>
    <dbReference type="EnsemblBacteria" id="ABX04230">
        <property type="protein sequence ID" value="ABX04230"/>
        <property type="gene ID" value="Haur_1587"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1587"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_0"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1611-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="5"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX04230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="43565" checksum="CBFD7BAA104673D2" modified="2008-01-15" version="1">MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAANYMDKKEARRNSRFVHFAVAAAKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRVMDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPVSACATSGNAIGEAWHVIRRGEAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVLEDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYLNAHGTSTPVNDRTETLAVKKVFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREGLLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFGGHNVSLLFKAFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S6</accession>
    <name>A9B4S6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3011"/>
    <dbReference type="EnsemblBacteria" id="ABX05649">
        <property type="protein sequence ID" value="ABX05649"/>
        <property type="gene ID" value="Haur_3011"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3011"/>
    <dbReference type="eggNOG" id="ENOG5031Y5Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065106_0_0_0"/>
    <dbReference type="OMA" id="ADIAMHT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3043-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="40130" checksum="AC9186776577EA06" modified="2008-01-15" version="1">MATVGPTKTTASRLNPAPTGYPPFSKRLDVLCIVFSIWLLIGLFIDGLAHAEQLIDTFFSPWHAVLYSGFLGITTVIGTVQIRNMYRQYPLTKALPQGYFPALLGIILFSFAAPLDLMWHEWFGFELRLDALFSPPHLMIISGAMLFGTAPLRTAWLQTQAGANLRGWRDLGTMVMSLFFLMAAVSFFTQYASPIVNAPFLSEPYLESTMSNIDMRGISTGIITTLVLIGILLLSLRFWPLPFGAMTLLIGGSTGLIWFVHNQSSQAYWPVVVWAAIVGLLADIAMHTWQINQQRPLAVRLVCSLLPASLFLGYYLIIMASMGLNWITHMWTGMVFEVAILGFCLSLIAIPPYSKNIAHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W8</accession>
    <name>A9B4W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3053</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3053"/>
    <dbReference type="EnsemblBacteria" id="ABX05691">
        <property type="protein sequence ID" value="ABX05691"/>
        <property type="gene ID" value="Haur_3053"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3053"/>
    <dbReference type="eggNOG" id="COG1079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040769_1_0_0"/>
    <dbReference type="OMA" id="MIFGNWM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3085-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="445" mass="47389" checksum="EC0CD1892C516C59" modified="2008-01-15" version="1">MKFTRARGVGLLGIFIAIVLIFAVNNSLGNKITEKSKIQSIWDFTSTIRIPDSANMKVDPKAPPVAAIELPTMITISLICGALVIAGGTLIAKNPERGWVAPYMSSVIALGFFSILLWAVANNSVDLSDTLSRVVRLGTPIAIGALAGIVCERSGVVNIGIEGMMLTAACFGYAAAAISARAIYGDALPESAVRGVVWMPLIIGILGAIVTGGMMAALHAWLSIRFKVDQVISGTVINIMAVGITGFTRTNFLLKFESPLRTGLPQMPLGPLADIPLLGPILFDHKPITYLMILMVFGLNFFLFRTVWGLRTRAIGEHPKAADTVGINVNRMRYRNVIIGGMIAGVAGAWFSLEGSFGFDDGMTSGQGFISLAAMIFGKWNPIGAFGGSLLFSSADALQLKVQAYSFDLPSQFMQMLPYVVTLIVLAGVIGRARPPAASGKVYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y8</accession>
    <name>A9B4Y8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3073"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05711">
        <property type="protein sequence ID" value="ABX05711"/>
        <property type="gene ID" value="Haur_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3073"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_6_3_0"/>
    <dbReference type="OMA" id="TPDWVKH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3105-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="19"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="477" mass="55721" checksum="5E713659C7FFDED4" modified="2008-01-15" version="1">MTTSDWQTPDWVKHAVFYQIFPERFANGDRTNDPANAQPWGTSPTLYNYMGGDLQGIIDKLDYLVDLGINALYLNPIFQATTSHKYNTFDYFKIDPHFGTLETFKTLLNEAHRRGIKVILDAVFNHCGRGFFAFHDVIENGVHSPYTNWFHISRFPIHPYESRYAANYRTWWDFRELPKFNTDNPAVRKYLLDVARYWIELGIDGWRLDVPNEIDDHNFWREFRTIVKDINPEAYIVGEIWTDGSAWLQGDQFDAVMNYLFRDLCTDFFASYRVRAADFAAGIDHLIVRYQPQVTYVQFNLLGSHDTARFLSVAEEAGKWALERMKLAVLFKLIFPGAPCIYYGDEIGLHGGKDPDCRRCFPWDQPQTWQTDLQAWTKRWVKFRHEHTALRTGHYATLFADNDMNIFACARWDEQSQFVIVLNNNETPWTLDLPLHAQLPSVTHYRDVQTGELYSVAEGKIREVALAPWKHLVLQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B1</accession>
    <name>A9B5B1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ordered locus">Haur_0084</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0084"/>
    <dbReference type="EnsemblBacteria" id="ABX02736">
        <property type="protein sequence ID" value="ABX02736"/>
        <property type="gene ID" value="Haur_0084"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0084"/>
    <dbReference type="eggNOG" id="COG0769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022291_4_1_0"/>
    <dbReference type="OMA" id="CFMEVSS"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="109"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="350"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="155"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX02736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="514" mass="55587" checksum="FEDEE404760B4751" modified="2008-01-15" version="1">MKSFAELLLHVTHQASGDHHVAISNVAYDSRKVTPGALFVAIKGVHVDGHRYIATALEQGAVAVVYDDPHQAPPATIPSALVADAKVALSPIAAAFYDYPAQQLEVVGITGSKGKTTTTFLTAAALEASGELVGFMSTVDFKIGQRQWANKTRQSTPEALEIQAMLREMVEAGCRYAVVESTSHGLSPRWNRLGDCAYDVALITNVTHEHLDYHGTVEQYRADKAQLFQLLATSPSQKSILGQPTPVEKVAIVNADDPHAAQFRAAAGEQVRHLSYAIHAEADLRATEIVSTSKGLRFTAITPQGNFALNLQLVGTFYVYNVLAALSVCLARGVDLAAAIQRLEAIPGINGRMEQVELGQPFSVLVDYAHNPDSFEQVMSMLRPLTQGRLIAVFGSAGERDLAKRPIQGQIAAKWCDLLYLTDEDPRAEDSLQILQEIAAGAKAEGKIIDQNCWLIPDRRTAIEQALATAQAGDVVLLLGKGHEGNIIYASGDIEWNEHAEAERALQGLGYIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P3</accession>
    <name>A9B5P3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1633"/>
    <dbReference type="EnsemblBacteria" id="ABX04276">
        <property type="protein sequence ID" value="ABX04276"/>
        <property type="gene ID" value="Haur_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1633"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_3_0_0"/>
    <dbReference type="OMA" id="ENDHQIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1657-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="123"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24802" checksum="BF638AB42AF4C7E3" modified="2008-01-15" version="1">MSREHYEQQLRSLNDDLLRMGALVETAIGQSIQALTNHDEAMAQEVIRSDDLIDRAQYALEEKALLLFATQQPLVARDLRLVSAIITIASELERVGDYAEGIAKIAIRQGQTPALKPQAEVPSMTSKAQLMLRTALECYTRKDVDLAKTLSAADDEIDQQTDRVQREILEVMIADASTVEQATRLLYVVHNLERIADRATNIGERVVFMATGHMADLNEQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q1</accession>
    <name>A9B5Q1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1641</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1641"/>
    <dbReference type="EnsemblBacteria" id="ABX04284">
        <property type="protein sequence ID" value="ABX04284"/>
        <property type="gene ID" value="Haur_1641"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1641"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_5_0_0"/>
    <dbReference type="OMA" id="LCITRAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1665-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="252" mass="26201" checksum="BC1D66069DF151D4" modified="2008-01-15" version="1">MSISLIVLALLVGASIGLTLGMLGGGGSILTVPALVYVLGLSAHDATTSSLVIVGLNAAFGAWLNCRRGPCMLRHAFVFGGIGLGAAFLGARVSQYIPEVWLLTMFGSLMLIIGSMMLRPKVQAKTDEQAIAWPAVVMGGLGVGFLTGFLGVGGGFLIVPALVLLLHMPMRTAISSSLIVIALNSSAGILGHLQGSHFDWTLIGLIISGGVIGNLLGTRFAQKVQVQTLQRSFAFFVIALGIFLVIKNFPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U5</accession>
    <name>A9B5U5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3100"/>
    <dbReference type="EnsemblBacteria" id="ABX05738">
        <property type="protein sequence ID" value="ABX05738"/>
        <property type="gene ID" value="Haur_3100"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3100"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047969_1_0_0"/>
    <dbReference type="OMA" id="QKMQFVL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3132-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="36"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="318" mass="35186" checksum="052525FC51F7B66A" modified="2008-01-15" version="1">MSNASRRPSGRRIGSIAIAIVIAVIGLVLLTASWKTIPPGYVGIAFNKANNNVTTAIDPGWTLINPFTTAIQQYPVTIQTYIMVQSDNEGQTAGDDSIKIQSSEAQQLNLDVAVQYRVKKEEAAVLYTDWGGQSLDVIELQVVRQQTRSILTTLAGRYSWEDISGEKRAELADKVKEQLTTEFERRHLILEDFVIREVHLPDNLKQALENKITAQQAAERQKYELEQAQIKAEQDKVEAQGRAEAQRATAKGDADSILIRAEAQADANRLLAESVTEVLIRYQMALRWDGKLPVFSGGGATPLVDVSELINSTQPISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B622</accession>
    <name>A9B622_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3178"/>
    <dbReference type="EnsemblBacteria" id="ABX05815">
        <property type="protein sequence ID" value="ABX05815"/>
        <property type="gene ID" value="Haur_3178"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3178"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_0_0"/>
    <dbReference type="OMA" id="RVIAGWD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3213-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12086" checksum="4833963C7673A187" modified="2008-01-15" version="1">MQTTPSGLRYEEQVVGTGAQPKAGQTVIVHYTGTLTNGTKFDSSVDRGEPFEFILGVGQVIKGWDEGLSTMNVGGKRRLYIPGNLAYGERGYPGVIPPNAELIFDVELIGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B630</accession>
    <name>A9B630_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3605"/>
    <dbReference type="EnsemblBacteria" id="ABX06241">
        <property type="protein sequence ID" value="ABX06241"/>
        <property type="gene ID" value="Haur_3605"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3605"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_0"/>
    <dbReference type="OMA" id="AHIQGSQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3644-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="30988" checksum="C7C76977C2FB2DD5" modified="2008-01-15" version="1">MPQAAINGITLNYEVAGQGAPLLLIMGLGGTTDGWRKELPFLTKHFQVIYYDNRGVGKTTAPTDFTAYSMEHFAADAIGLLDHLGIERAHVWGVSMGGMIAQHVALNYPERVQGLVLGCTLPHYANDPANIPALPDEFHAEASNLAPEAWVLELMLSGTQKTAHEVMQDSVRFNFAPAFVEAHPEVIEEYIEVGMQNHGPAHGFMGQWSAIMNHSTIERLPKLQHPTLVQHGDADVLVPIGNGRLLAQIIPNAEFQLIPGSGHCYFIEQPELASQGVQAFLQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B633</accession>
    <name>A9B633_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3608"/>
    <dbReference type="EnsemblBacteria" id="ABX06244">
        <property type="protein sequence ID" value="ABX06244"/>
        <property type="gene ID" value="Haur_3608"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3608"/>
    <dbReference type="HOGENOM" id="CLU_2601259_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3647-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="79" mass="8074" checksum="5B85496A091C76AE" modified="2008-01-15" version="1">MQLIGSIVILGFGLAHLGLGAILLATGYRTLTNEIIPRLVEARPSAGARVGAVLGGVGWTVAVALFCFLVAGRAAQMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B663</accession>
    <name>A9B663_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Beta-galactosidase</fullName>
            <shortName evidence="5">Beta-gal</shortName>
            <ecNumber evidence="3 5">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 42 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3638"/>
    <dbReference type="CAZy" id="GH42">
        <property type="family name" value="Glycoside Hydrolase Family 42"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06274">
        <property type="protein sequence ID" value="ABX06274"/>
        <property type="gene ID" value="Haur_3638"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3638"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012430_1_0_0"/>
    <dbReference type="OMA" id="SRRHYCF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3677-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013738">
        <property type="entry name" value="Beta_galactosidase_Trimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003476">
        <property type="entry name" value="Glyco_hydro_42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36447">
        <property type="entry name" value="PTHR36447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08532">
        <property type="entry name" value="Glyco_hydro_42M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001084">
        <property type="entry name" value="B-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glyco_hydro_42" evidence="9">
        <location>
            <begin position="6"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42M" evidence="10">
        <location>
            <begin position="384"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="644" mass="72587" checksum="AAE0CE48B0BAE588" modified="2008-01-15" version="1">MPLGVCYYPEHWPQTWWADDAKQMQALGLEYVRIGEFAWALMEPAAGQYDWVWLDQAIETLASQGLNIVLGTPTATPPAWLTHNQPDLMRIDAQGRRLGHGGRRQACLVNPQYIEYSRQIVTAMAERYGQHPAVAAWQIDNEIGNHGSARCYCEHCAAAFRQWLIQRYGDLAGLNEAWGTAFWSQTYSDWQQIPLPNVPVGGGHNPSLVLDYRRFASDQQVAYCAMQAEILRQHSPNRTILTNIAPGDDEINWFDMAQQVDTIAWDNYPHGFPDWQAVAMYHDHIRGLKRQPFWVMEQQPGQINWTPTNPPVPPNQVRLWSYQDAAHGAANVLYFRWRACWLGQEQYHSGLRDHANRPARGSTEARIVANEWQQHGQPEAAPRKVALLVSYDDHWAQQLDPHAQGWNYWQLLRTIHRTLTSYGVGVDIVQRGTPLAAYQLAIAVAPMLDNPAETAGWREWVQAGGTLICTPRSLTKRRDNRTAPDGFPSGLTDLFGADVAEWSALDPAKPWAVKFGETSHTAPLWMEVLNVSHANSLATWSKSYAKGQAAITAATYGKGLAVLMGCYPTEEILGDLLPRLWPAAQRLPNEIERIELTDGVLWFNHGEQAQSVKLQGTWHDRLSGEQCSGDCSIESLGIRWLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B678</accession>
    <name>A9B678_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3653"/>
    <dbReference type="EnsemblBacteria" id="ABX06289">
        <property type="protein sequence ID" value="ABX06289"/>
        <property type="gene ID" value="Haur_3653"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3653"/>
    <dbReference type="eggNOG" id="COG2856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_535035_0_0_0"/>
    <dbReference type="OMA" id="VEGYWYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3692-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="509" mass="56381" checksum="0B116790AE6E362B" modified="2008-01-15" version="1">MNRTRSVIVGLVVLLLVALGASGWLWFERGTIISRDATTQAEFGKLKDQITAADEVQDKNRQLQDQVNDLQERLNNPPTSIAEPTSPALEPTPEAGPTPTVDPAAPTPTGPGGVEPPAQIVEVMKQIEQEVIALRGLPEERPVTRRMLTRDELRDYIVREMETENTPEDFRRETSQLWMLGLAEKDIDLQQLYIDLQTEQIGGFYDPETDTFYIIAENSEFPPADQITYAHEFNHNLQDQLINLQDGLKVGEFDADRSLAFRSLVEGDATKLMSDWLQNDLIPRMSPAELQELLRTLQEQQDSSSILDQVPGVLRDGLVFPYEDGLAFAEAVYAEGGWEAVTKALQDPPTSTEQILHPEKYLSATRDNPTLPDQFDLLPVLGADWTTAMTNTVGEFDVKALLEYTATAGDMEAAAAGIGGGRMTLYEHNSDFTPVLQWTLRWDSAADGDEFLSLFNGTLNPNGDLLLRAGDPNRSDDDVHVGVKGSGQEFVIIFSSNQDLVRNALNALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B692</accession>
    <name>A9B692_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06303">
        <property type="protein sequence ID" value="ABX06303"/>
        <property type="gene ID" value="Haur_3667"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3667"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_439967_0_0_0"/>
    <dbReference type="OMA" id="VFISEYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3706-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="623" mass="69863" checksum="4DCE6E05F3D60BA0" modified="2008-01-15" version="1">MSNPTNAPAQPTWSGSNEQQTLAERAFNVMMLQSAFFPENVPVRQTVANLAAFIASQDGLDASALEATISAALEANSQIFRRIDDGERVVYATTRLGYYTEPQIDTRHTFAKRLHEPENPLPIDDLSVVITRTRPALTTIEPVFISDYWQQRSPTTGEEGEIINVAPISPSSDVELDETFEDEVEPVAVAPVVVAPAAVVEAPTPVVATNSTTLVLPGGAALDFAQSVEHILAAHGSTIQAALSEAIDNDPLRRIVAFGDEYFAEENIPTLSKGDLRRIREYIVEQGEPMPDTSILSDVYYRNPRDNDYVTFRFALNYRLNREKDFEFVGVQGARLWSAKGLPAVGTKRLKTSELGQFYSFLEETPHFDDSLKQTSPDDIKQNRQMSRFLSFFEWEYGVLPYDAAMKALLPQPLLPEQRTAILRIESPQHYSFYLAELRYPTANRGGWLHGLEDFFKEHLVPGALITLSATDDPSVWTLQYEETSGADVKLLQQDDKKGRYAFVKHTFYCDADNDLIASQERLPRLKNMKVLTPGERRRLATTAGYVLEQVGQPRPGDRAGFELSIDDLFLGVNVQRPATRSYLLGELAEEQDFFIEETAVIYFPPPEDETSVENKNFVEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B8</accession>
    <name>A9B6B8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3693"/>
    <dbReference type="EnsemblBacteria" id="ABX06329">
        <property type="protein sequence ID" value="ABX06329"/>
        <property type="gene ID" value="Haur_3693"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3693"/>
    <dbReference type="HOGENOM" id="CLU_823290_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3735-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37614" checksum="2EB1DC4C7EC2B2BB" modified="2008-01-15" version="1">MMAAMMIQTLSELYPDLRRLRFGSIVYALLTDTTPENQQHRIILDAALREAGSRGWLTPEVFGRLRAGDDAVVLSILDELLIAQALDRANYSLQFNPPGEGRHVGELLIERGDLRSFIEVKSLLPAEAVVLAQTTLARLRDLASTIPLAARLTLEITHHPNSGISHREVRRYLHVAAEQMLSGWTHPAAYTHSSGIYLRPVDCQPLPEAEHLQIDLYQEEYPGLARRAHRAWCDRLWRAIRGGYTQLPAGEPAVIIVVDHAQPAPPLEAWLAPLGDMLRMGAHHRLSAVIRIELASLRTGQPALTIFHNPRASSPLVSQPILGQHELHISMLNPETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S4</accession>
    <name>A9B6S4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1740"/>
    <dbReference type="EnsemblBacteria" id="ABX04383">
        <property type="protein sequence ID" value="ABX04383"/>
        <property type="gene ID" value="Haur_1740"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1740"/>
    <dbReference type="eggNOG" id="COG4114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085298_0_0_0"/>
    <dbReference type="OMA" id="LHDYAWS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1767-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024726">
        <property type="entry name" value="FhuF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022770">
        <property type="entry name" value="FhuF_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06276">
        <property type="entry name" value="FhuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11575">
        <property type="entry name" value="FhuF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="FhuF" evidence="2">
        <location>
            <begin position="67"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="FhuF_C" evidence="3">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="28948" checksum="ABBACE691EE3FED6" modified="2008-01-15" version="1">MSVGSSPLAQSLERAATLDQYLVARIAEPNEPDWLPATSLTDPATLSTILEGFAASRKLAKRRLTGSFFISSYVWYLAGAAIASLLIDQRIPDLDRANVLARFPSNGNADQAAIAFASQRFFGLAGDQSQAGATVVADKASLREQLRQQFEQHLEPVVQLVADQSGLGQRAQWNIIADRCAGIFLRVGQRLDQVAAACEEGLAFVGAKGSAMKASKTGYIELNTASDASATFLQRGGCCLYYQVEGGRNCNDCPLLPTAERLQRMAGLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U8</accession>
    <name>A9B6U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04407">
        <property type="protein sequence ID" value="ABX04407"/>
        <property type="gene ID" value="Haur_1764"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1764"/>
    <dbReference type="HOGENOM" id="CLU_1701843_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1792-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="98"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17557" checksum="3EBE13B67C52B714" modified="2008-01-15" version="1">MSNQPNYQSPTPPNNQPNYAQPYDPNLYQGQYPPQTLYGQNPYQAQYQPINYPYQVPNSIQANAKIDRQRSNIAFVVCIVTFILGGVFYSRNPQNSDAILSGFFWLFSSIAWVTAWCFSTKSKGYSVWLGLLSLLGLLGMLILMVIPNRNKLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J1</accession>
    <name>A9B7J1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltranfer_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0312"/>
    <dbReference type="EnsemblBacteria" id="ABX02964">
        <property type="protein sequence ID" value="ABX02964"/>
        <property type="gene ID" value="Haur_0312"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0312"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031012_1_0_0"/>
    <dbReference type="OMA" id="CGYETKV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-315-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="158"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="388" mass="43427" checksum="9958F3FEBC7667E3" modified="2008-01-15" version="1">MQLTPENYHEQLIALALTDDFVRLTMSGAARATDLRWQRVVVRPVQLKQGRAWQAAYFDQRQNITKNYAIEQASSALGEIIAIPLSNITLETTSERIQIQRSKKGKVIISRVRNQAAAPDLRHNHVKALPLPSDSPDAYLQKTGIMTNDGVIRASMSKKYTQINEFLRVFDELDLKPSPEQPLRILDAGCGSAYLTFAAYHYLVNIRGLAAVVIGVDSNEYLIAKCRAQAEELGYTDMQFIAMPLADWQPEQQPDVVFSLHACDTATDDALALAIRSQAQAILSVPCCHKHLTHQIQAEVLNSMLRHGSIRQRTADLVTDSLRAQLLRINGYRSEIIEFVDAEQTGKNLMIRAIRSKKPDSKAVAEYQALKQFWGVTPYLEQLLGSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q7</accession>
    <name>A9B7Q7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1792"/>
    <dbReference type="EnsemblBacteria" id="ABX04435">
        <property type="protein sequence ID" value="ABX04435"/>
        <property type="gene ID" value="Haur_1792"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1792"/>
    <dbReference type="HOGENOM" id="CLU_846682_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1820-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="37638" checksum="DE7FDEEDDA44F046" modified="2008-01-15" version="1">MGAKTKDIIVVNAFDEVYLMQKTTNDHDPLAELDRQWDQERIGYVGVHNADRRIKIASLSVVGSLLFFFILAGAAFLKEGINQGDVQFFLATLLIFGFSLVLGFGLHAIIRLRLAERRYLKKRAKLLHTLPALAQTKPLQYSYRISSPLNPQSAQWTAAETQIYTLQELHYAEPKRDKAYAAAIQKIIVDAPKSEQAYLSELVQLEQRWVVERLRYRNIQPYYQHYHYRQLANEDEVSYPLPMKTWMVLVIGIALLGLGCMLAWNGSTTWLNILLVCSFGLVWIFTARELYRISPNLQRAEQNYINNQYALAQKHDRLASSSDLGLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S3</accession>
    <name>A9B7S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1808"/>
    <dbReference type="EnsemblBacteria" id="ABX04451">
        <property type="protein sequence ID" value="ABX04451"/>
        <property type="gene ID" value="Haur_1808"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1808"/>
    <dbReference type="eggNOG" id="COG4779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_1_0"/>
    <dbReference type="OMA" id="QRLFMPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1836-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="38023" checksum="A6B44DD55F59C692" modified="2008-01-15" version="1">MDRLSLNPTTSAAHELNLAQPFTGQPTGLWLLRFGRLSLLLDRRAWLASLLLLLATVVLVGLSLGSGTVKIAPLDALAALFNQGETKNIFIVRDLRLTRVLAGGMAGAALGMAGCLLQTLSRNRLANPDTIGIDNAATAFAVASVVGVSTTLAPSGMALIGAITMLSLTFALSGGAGTRGYRFLITGLGLGAICGAATNLMLARAPIDAANDAFPWTIGSLNDRSGITVSLLAWGVVILLPLAAIVGKRLNLVRLPDAVAQSLGVRVNRLRFFTILLAGSLTGLAVAVAGPVGMIGLAAPELGRRLAGPRTVPIVPSALAGACFTMLADLLGRTLFSPTEIPVGIVTALVGGPYLLWFLLRTPRGKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7V6</accession>
    <name>A9B7V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coproporphyrinogen dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.99.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1841</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.99.22" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1841"/>
    <dbReference type="EnsemblBacteria" id="ABX04484">
        <property type="protein sequence ID" value="ABX04484"/>
        <property type="gene ID" value="Haur_1841"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1841"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_7_1_0"/>
    <dbReference type="OMA" id="SMRMFRA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1870-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="39"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="49673" checksum="ED8B7B017E2E6CC1" modified="2008-01-15" version="1">MHLREYANATPYMGYSYSYPHKSAYRQLEPRSLREVWADEAHDQLFLYLHIPFCEMRCGFCNLFTTTNPNESVVQRYLATLELQMQALHNELGAVQFSRMAIGGGTPTYLSASELEQLFSMSQRWLGVNSRAIPLSVETSPHTATADRMAILAQAGVDRVSIGVQSFLDHEAHAAGRAQRRPEVEQALATVRAAQIPTLNIDLIYGLPNQSVATWLESLEIGLQWRPEELYLYPLYVRPLTGLDRRGTGWEHDLRLECYRAGRERLLAAGYQQISMRMFRAAHAPDDSQAPRYCCQTDGMLGLGAGARSYTRKLHYSSDYAVGASSVRQIIQNYNQRSLLDLSQVDYGCVVSSTEQRRRFVIQSLLQVSGLDTQAYRAQFGSDVLADLSQINELIEIGWAEYQHGIYQLTPAGLERSDLIGPWLYSPQIRQLSAEFILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X1</accession>
    <name>A9B7X1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1856"/>
    <dbReference type="EnsemblBacteria" id="ABX04499">
        <property type="protein sequence ID" value="ABX04499"/>
        <property type="gene ID" value="Haur_1856"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1856"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_23_7_0"/>
    <dbReference type="OMA" id="NGRNIWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1885-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05931">
        <property type="entry name" value="FAAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040097">
        <property type="entry name" value="FAAL/FAAC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="579" mass="62688" checksum="E3E51EF16314B3C8" modified="2008-01-15" version="1">MLDHDLMLEAGGSSATIQSNPASFVEIILQRAKTTPEAIALNFYTADGYRTSLSYGLLAQRCQAIAAVLQRVTKPGDRALLLYPPGLGYVEAFFGCLFAGVIAVPAYPPRPNRRDQRLEAIISNAQARVMLAASEVVAQQRALSQQYPGLAQLQWIASDLVNSQLASMWQAPSINTHDLAFLQYTSGSTSQPRGVMVSHENLVYNSGLIAQSFGITADDHVFIWLPPYHDMGLIGGIMQPLFTGCELSLIDPLTFLQQPLIWLRMISDLGVTVTGGPNFAYDLCVAKAKPEALAGVDLSRLRVAFNGAEPIRAATLERFSRTFAPLGFKPQAFLPCYGLAEATLFVSGAPHAAEPTTLTVDAQALSQHQALPSERGTLLVSSGMVAAPQIVAIVDPEQGQVCADGWVGEVCIHGRSIAHGYWDNSAASEATFQLILPDGSGPFLRTGDLGFIHEGQLYITGRLKDLIIIDGRNHYPQDLELSVELAHPAIRQGGCAAFAVDGADGEQIVIVAEIRRPNQAEEAAQAVRLALQQQYDLAIADLMWVRPGQVPKTSSGKVRRRECRQRYLSQTLNSLEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X3</accession>
    <name>A9B7X3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1858</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1858"/>
    <dbReference type="EnsemblBacteria" id="ABX04501">
        <property type="protein sequence ID" value="ABX04501"/>
        <property type="gene ID" value="Haur_1858"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1858"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_2_0"/>
    <dbReference type="OMA" id="MFRPGDD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1887-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1528" mass="169722" checksum="F2D62442ABE2E19E" modified="2008-01-15" version="1">MTMNEREVFAFPMSFAQQRLWFLEQLQPNSALYHIASLLEIQGSLDLAALQQSINQIVVRHETLRTTFGMVDQTPMQLISSELTLTPVVHNLQALEPEQRWFVALEQAKASCLVPFDLSQGPLVRLELFQLGPEHCLMTVVLHHIIADGWSMELFIQELVSSYEAYRAGFHPQLAPLALQYADYSEWQREWLASPRQQQQLDFWQQQLADAPKRLELATDHPRPAQQSFAGSTLSFGIPSQQTSQLRSLAQQTQTTPFMLALAVFASLLSRYSRQDQVLIGSPIANRTTAEAQPLIGFFVNTVVFKVQLSPNLDLLSLVEQVREQSLAVYANQDVPFEQVVQQLQLERNLSHTPIFQVMLAYQNVPSQQLSIANLTIKQLPLDLGYAKFDLTLFIEETPAGLVGRLEYNRDLFEPATIARLRDHFLRLLGHALAQPTQPLAQISILSAAECQQLLVDWNQTQQPFPDQLGLQHLVAQQVQRTPNAPAMRWNNQIICYTELEQRANQLAHLLLQRGVTQGSIVGVYATRCPEMIISLLAILKAGAAYLPLDPAYPAERLHYLVADSAASLIVQASHQALPTLVSTAETLDVVAEAETLASLPTTAPMVDFDPQQLAYVIYTSGSTGKPKGVLIQHQGVVNYLHWAIHYYPFEQGAGAPLASSLAFDATITALWGPLCTGKTIDLLPEQDELEVLAQRLSSEDYSVLKITPAHMEALSQLVAPDQIGSSKAFVIGGEALLQQHVAFWQTNAPNLRLINEYGPTETVVGCVIYQAQAAPSEWAAVPIGRPIANTQLYVLDPAGLPVPIGVPGELYIAGLGVGRGYHGRPELTAERFVRLEQLAGVQAELARCQQPQPAFERLYRSGDLVRYLPDGNLEYLGRIDQQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHKRLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWLDSLPLTPNGKVDRQALPAPEINQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANFFSLGGDSILVMQVVGIARQHGLILTPRLLFQNQTIASLAQAIRQQTQAKPALDPLSLQGIVPLSPMQHWLFERQLAQPAHVNQSIVLKLQTGLATEQIQAALDQLVRLHPSLRLIFTQTAAWQQRYEPAASVPLRELQQPTLSQQQVCDAELQASFDLAQVPLLRASLWRGIDHDQLLLVAHHSIIDGVSWRIVLEDLALLLNQQAVPAATTPFSEWAEYQVQQAQTPQLLSQLAYWRSTIEAITPIPQLAQAGLVGEAQRFQTKLNPELTEQLLHHAPERSRTSVAELLITGLAIAFQRWSNLQQLVLDIESHGRESLDPEHDFSRSLGWFTSLYPVRLDFPTTNEPNQWIKQIKESLRAVPQAGAGYGMLRYLHADPAIRASLVPTHAPAIAFNYLGQLDNQQTLAPFQGLNLEFASQTLAPTNQRSHALELNCYSTDGCLVFDWECHQTARAAVEHLAEQYQIALAELLQVPTTTASLAPSDFPAARVKANDLDRLLARLKAKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B884</accession>
    <name>A9B884_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3801"/>
    <dbReference type="EnsemblBacteria" id="ABX06437">
        <property type="protein sequence ID" value="ABX06437"/>
        <property type="gene ID" value="Haur_3801"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3801"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808713_0_0_0"/>
    <dbReference type="OMA" id="KPPILWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3843-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="35"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="38102" checksum="78B8D4D77192547B" modified="2008-01-15" version="1">MLNPPLLAGLTARVVQMPRLAMHVIERGDPSKQPIVLVHGNVSAARFWEELMLALPDDYYVIAPDLRSYGRSERLPLDATRGVRDFSDDLDSLLQTLNIRRPHLVGWSLGGNVVLQYALDYATNVRSLTLVAPGSPYGYGGTQGLDGQPNSHDYAGSGGGTANAAFVEALKNEDRGDGPVSPRTIMNSFYFKPPFRSSREDVFVDEMLQTYCSPQNYPGDLVASANWPMVAPGTGGVNNALSPKYLNQSSFASIQPQPPVLWIRGDADQIVSDASMFDLCMLGQLGLVPGWPGAETHPAQPMVGQMRAVLENYAAHGGQYQETVLANCGHSPQIEQPSLFNTALLDFLTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K6</accession>
    <name>A9B8K6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07670">
        <property type="protein sequence ID" value="ABX07670"/>
        <property type="gene ID" value="Haur_5040"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5040"/>
    <dbReference type="HOGENOM" id="CLU_123192_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5103-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016787">
        <property type="entry name" value="UCP021328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11208">
        <property type="entry name" value="DUF2992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="13786" checksum="D7166BE7FF9B4E25" modified="2008-01-15" version="1">MPHFTVYRDGPWWVGVLEWHEDGMHYAARHTFDSEPSSPTILAFVLHGGWLRLFAHHLVGVRNHQPAALPSNAKRRQRTVSRQAQHCGISPLTQTALDQSRAAYRTTDRTREDSSAASDTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L6</accession>
    <name>A9B8L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07680">
        <property type="protein sequence ID" value="ABX07680"/>
        <property type="gene ID" value="Haur_5052"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5052"/>
    <dbReference type="HOGENOM" id="CLU_133181_2_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5114-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021257">
        <property type="entry name" value="DUF2809"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10990">
        <property type="entry name" value="DUF2809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14243" checksum="AAF29B2551B45D8C" modified="2008-01-15" version="1">MQVIQRRSIMLGGIVLGGILSRLVSTGFVVVDHYLGDALYAAMVFVLLLLFAPMRSRATTALVALVIVVLIEAFQLTGIPLQLRSADHGLLRLLAVVLGTTFNGWDIVSYAVGILVGFGLDWRMVSTTTRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8M4</accession>
    <name>A9B8M4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07688">
        <property type="protein sequence ID" value="ABX07688"/>
        <property type="gene ID" value="Haur_5060"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5060"/>
    <dbReference type="HOGENOM" id="CLU_780255_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5122-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734631" evidence="1">
        <location>
            <begin position="25"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="38826" checksum="56C756C122F683AB" modified="2008-01-15" version="1">MGRRLWVLGLLLCGVLIGCGPSDATGTVESATVPTLPPVPTVALSGAAALHATSTTVAATRAPIQTTFALDEQATAAAQPAEQYLTLREAFARGGIRERGTAWASDAVLVDAGIGYRAEGRVQEGMFAMIAANDGTARWWAFTFASARLKQTLVILMQDGVVTRSYADERSYRDLFVGTAPVDIPLESKPFLDSDQVRVLFLNFGDLWEKMASPNHTFRLASLPNDYAAGHAIYWWMQDTYTNATLLDPITGAVIDSARTQKTTMTPPAKTRVPLVADLVPTIQPTPTMPWTDAEVAQVFWPTPRAGEPLRVIGLYASNGVDYWIYRQGRWDELWGNDKDRINLLRLGFPLELVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB2</accession>
    <name>A9AUB2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0380"/>
    <dbReference type="EnsemblBacteria" id="ABX03031">
        <property type="protein sequence ID" value="ABX03031"/>
        <property type="gene ID" value="Haur_0380"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0380"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118613_1_2_0"/>
    <dbReference type="OMA" id="REVITRC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-383-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="PTHR13323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="13136" checksum="65C644813C7438B6" modified="2008-01-15" version="1">MASRSEQINTILGQLVTNNGNDINGAALISSDGILIGSRMSADVNADRMGAIAATMMGVTTRVVNDLKIGKANEAIVNAESGYLLVMPVAAQMILAIILRQHANLGMIRIEARETGRAIAELMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF5</accession>
    <name>A9AUF5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0423"/>
    <dbReference type="EnsemblBacteria" id="ABX03074">
        <property type="protein sequence ID" value="ABX03074"/>
        <property type="gene ID" value="Haur_0423"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0423"/>
    <dbReference type="HOGENOM" id="CLU_1658410_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-429-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="18048" checksum="89DC6029C4B38533" modified="2008-01-15" version="1">MQQLVLACGYNPFGYVIFFFIMVIPFSLTLGIKWFFLAQTLRASHRSLFLHSLGLTFIVGLVIGFVFISAYILPTSLFVIEIGGFYSYQFFIWAIVCIVDTFLIERWLLKPKAQAISLTDDQQLQVEAAAIKYQPSWVAALLSNTLIAIVVALFFQMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ5</accession>
    <name>A9AUJ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1879</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1879"/>
    <dbReference type="EnsemblBacteria" id="ABX04522">
        <property type="protein sequence ID" value="ABX04522"/>
        <property type="gene ID" value="Haur_1879"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1879"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_3_0"/>
    <dbReference type="OMA" id="ADRLACW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1908-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1258"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2324"/>
            <end position="2399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1293"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2419" mass="267843" checksum="EF73E09E995D7FE8" modified="2008-01-15" version="1">MQTGSIEGFRLSPQQKQLWSLKYSAEINPYLAQCSVDIQGALDVQRLQAALEALVQRYEILRTQFAQLEGMSMPLQVVGEGQLNWQTLQADDRQAAWDEALGSPIDVAQGPVLWARLMSLSNEQHQLILTLPALTADLTTLNLLVYELELLYSQEGQPDQEVAQYIDLAEWLNDTLATDASEPGPAFWQSHDLQTVANPVLATLADPSPSFTPAIHELTIATPNLPSQELASWLLAAWQVVLWRNSNQTEFQLGLGLDGRNYAELEPALGLFAKHVPFFAQIKPELRFSDLVSQTRTAYQQATTWQEYWAWEQFSDAAAHHLDYCFSYASLPQPPFEHAPRFRLSQQVCYFERFVAKLELLEIGNMLQSRLVYDAQLLSVEFVQRLAEQVATVCQQVQQSDQLLLGELAVVGASERQFLLELNRRYQTFDLQVTIPSLFAAQAQQHPTAQAVVFEDQSLTYQELEGYSNQLALQLREHGAASEQIVAIYLERSIASIVAILGVLKAGAAYLPIDPSVPNERLELMLADSRAVVVVTDQGLQTRLGHMQSPIVLIDQLLSNPPQADLGLNVAIQPEQLAYIIYTSGSTGKPKGVAIEHRQLANYVQSIIQEVDLRPGMQYAMVSTLAADLGHTVLFPALCHGGTLHLIAQDRAINADAMAEYMHAKAIDVLKIVPSHLTALLAASQPAHVLPKQRLVLGGEASSWDLIERLEQLAPTCTIVNHYGPTETTVGVLTTKLSGCSPAARGSIVPLGRPIANSYVYVLDAARQLVPFGAIGELYIGGAGVARGYLNRPELTNERFVTDRLSTNPSDRLYRSGDVVRYRPDGLLEFLGRSDDQVKIRGYRVELGEISHTLERHPLVQQSTVQLREHASGEQQLVGYIVPNPALALPVSNFLRFKQQGIFAEHEHFELPNGMLVVHQNRHMTVPLYNEIFEDQVYVTQGIQLNDGDCVFDVGANIGLFSLFIGQNYRNIRLFSFEPIPATCQVLRLNAELYGLNAQVFECGIADAVKQETFTHYPHFSGASGRFADVLKDKAAVQTFDLNIRKEYFSSTVGALAGDQEQAFMEDFTEEWMQGRWDSEQIVCQLRTISDVISEHNVQQIDLLKIDAERSEIDVLKGIAPSDWPKIRQIAMEVHSAELRDEIKQLLEAQGYHVIADQAEQFADTALFNIYALQPAVYQANQQASARPTTPTWAWCNPTSIINALQHYSHETLPEPMQPAALLLLPAIPLTANGKIDRQALPVPEQTIANTLTTSYVAPRNTVEDVLAGIWAKAFNQPRIGIHDKFFDLGGHSLMATQLIARIQQAFQVQVPLRSLFDTPTIAGLAEQIDASLRAGSVLQMPPITAVAHDRALPLSFTQERYWILDQFEPGNPAYNVPTYARLKGPLSHELLERALTEIVQRHAILRTTFIVLDDQPMQIIHPEVAVSLPLVDLSDLPVQDREQQARQIVATEARTSFDLAQGPLFRGQLIRLDETDHILLIMMHHIITDDWSKNLLIQELTALSWAYFRGEPSPLPPLAIQYADFAHWQRQWFQGEVLESQLEYWVKQLEDAPMVLNLPLDRPRPALQNFQGLSLPVYLPRRLTDQLAALSLREGVTMAMTLLAGFQTLLHRYSGQSDIVIGSYMSGRGQVGTEHLIGFFLNTLPLRVSLAGDPSFEVLLKRVQEVSLGAYSHQDLPFEKLLQRLQPEHNLSHTPIFQVGIQLVNALKSEAELGALTISDVESSQTSVMGTAQLDLTLTIRGLGSDEGLNASFIYDSTIFEQATIARMAGHLRQLLESIVAQPELPISQLSLLGENETEQLLDSWAGDHAQYPSDGSIQAWFANQVAQKPTATALVFGEQQLSYAELDQRSSQLAGYLQSLGVQAFATVGICMQRSPELVVAMLGVLKAGAGYVPLDPATPTERIRFILRDTAAPVLLTQAALKLDLADADWQIVALDQLDLTADHPVLNPLPSSLLNDLPVYTIYTSGSTGTPKGVPISQRNLLPMLRWGQAYFGLGQHSRVLQTLSYAFDFGAFELLTTMLSGGTLFIAPAGQLEDLASYRSLIERWQINTIHATPAFFAEVVALAQPMPTLEIVHLGGDALQPALVKQIQALVAPTCRIYNGYGPTEASVNCAIYQVEPERLADVVNVPIGRVTANHQLYILDAQLRPVPIGVVGELCVAGPSLSQGYLNQPALSAEKFVPNPFAAQPGQRLYRTGDVARYLPDGLIEHLGRIDHQVKVRGYRIELGEIEAALLNHPAVQEAVVLPTSEASLIGYVVLKQAGSTPTSELREFLQQRLPGYMLPAILVPLESLPRTANGKINRQALLATSALPERETPFVAPQGEIEEAVVQIWMEVLKRDQISVHDNFFHIGGHSLLGTQVIYKLAKALQINISLQTLFKHPTPATLALAVEDILLEEIEHLSDEELALLSQDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ9</accession>
    <name>A9AUJ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine ammonia-lyase</fullName>
            <ecNumber evidence="1">4.3.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1883"/>
    <dbReference type="EnsemblBacteria" id="ABX04526">
        <property type="protein sequence ID" value="ABX04526"/>
        <property type="gene ID" value="Haur_1883"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1883"/>
    <dbReference type="eggNOG" id="COG2986">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_3_2_0"/>
    <dbReference type="OMA" id="MYVHSIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1912-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="552" mass="60236" checksum="29280047171D6E77" modified="2008-01-15" version="1">MSTTLILTGEGLGIDDVVRVARHQDRVELTTDPAILAQIEASCAYINQAVKEHQPVYGVTTGFGGMANVIISPEEAAELQNNAIWYHKTGAGKLLPFTDVRAAMLLRANSHMRGASGIRLEIIQRMVTFLNANVTPHVREFGSIGASGDLVPLISITGALLGTDQAFMVDFNGETLDCISALERLGLPRLRLQPKEGLAMMNGTSVMTGIAANCVHDARILLALALEAHALMIQGLQGTNQSFHPFIHRHKPHTGQVWAADHMLELLQGSQLSRNELDGSHDYRDGDLIQDRYSLRCLPQFLGPIIDGMAFISHHLRVEINSANDNPLIDTASAASYHGGNFLGQYIGVGMDQLRYYMGLMAKHLDVQIALLVSPQFNNGLPASLVGNIQRKVNMGLKGLQLTANSIMPILTFLGNSLADRFPTHAEQFNQNINSQGFGSANLARQTIQTLQQYIAITLMFGVQAVDLRTHKLAGHYNAAELLSPLTAKIYHAVRSIVKHPPSPERPYIWNDDEQVLEAHISALAHDIANDGSLVSAVEQTLSGLRSIILFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU7</accession>
    <name>A9AUU7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3901"/>
    <dbReference type="EnsemblBacteria" id="ABX06535">
        <property type="protein sequence ID" value="ABX06535"/>
        <property type="gene ID" value="Haur_3901"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3901"/>
    <dbReference type="eggNOG" id="COG2261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160040_0_0_0"/>
    <dbReference type="OMA" id="MNIIAWV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3943-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9141" checksum="3CC3A37129DA39E0" modified="2008-01-15" version="1">MLSLIAWLLFGALIGWVASKIMNTDAQQGTVLNIVVGIIGAFIGGFLINRDVTANVFNLWSVLTSLIGAVVLLGIVNLFQRGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV53</accession>
    <name>A9AV53_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03131">
        <property type="protein sequence ID" value="ABX03131"/>
        <property type="gene ID" value="Haur_0480"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0480"/>
    <dbReference type="HOGENOM" id="CLU_1616757_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-486-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="17661" checksum="FA1D0EEB6BDE40E0" modified="2008-01-15" version="1">MDWIKRLGSMLLIGLIGLFVVGIVVDPGNANSATSTKLVQASGGPTATPPPESVLQSPADNAVLAQPIAPNSWTFNWQGPRCGHKIYLNGPGDRNYIFNGTMGSGPPPSSFTYSYTQTQALPADALEAWNWHVEYDCGSFQGQSVTRTFKVVPANFVYLPYATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV61</accession>
    <name>A9AV61_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar-phosphate isomerase, RpiB/LacA/LacB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0488"/>
    <dbReference type="EnsemblBacteria" id="ABX03139">
        <property type="protein sequence ID" value="ABX03139"/>
        <property type="gene ID" value="Haur_0488"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0488"/>
    <dbReference type="eggNOG" id="COG0698">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091396_4_1_0"/>
    <dbReference type="OMA" id="ETHHANQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-494-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="15636" checksum="AFAA503AE00F3886" modified="2008-01-15" version="1">MIMKIAVGTDHGGLILKQAVIEEVQRLGHEVLDFGTDSPASVDYPDFAAAVGNAVVSGQAERGIAICGSGVGVTVAANKIKGVRACLCHDTYSAHQGVEHDDLNVLCLGGRVIGPALAGEIVQAFLSATFHNEARFTRRLDKVIALENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV78</accession>
    <name>A9AV78_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0505"/>
    <dbReference type="EnsemblBacteria" id="ABX03156">
        <property type="protein sequence ID" value="ABX03156"/>
        <property type="gene ID" value="Haur_0505"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0505"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841395_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-511-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="56"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36557" checksum="DD12644595FFFB13" modified="2008-01-15" version="1">MQQLDLLWETGDAAQALQQRFGWDAASASAWVSALLHEHYGLDDIQIVRWSISAGNAIIWLKHDQECWIFKISADRDRHRQIEQSVELQHWLSVQQMSVPLIVPTTAEQRVLKINERCVYLQRWLDGTPPNPDSSQQLWRIGEETAKLQRILSAYPQAGQLPQVLLPLEQVCMGLAAWLGNTADAAPLQQELAQLAQQGLEHLPSGVCHNDIRAANLLFNGDQLQAVLDFEEVGWRCLVLELAWTAVHGLTMYRNWQPCTASQQQAIIAGYQSIRPLTEAELAILPSLCRLQSLYLLCSQGATAADAIQRLKEINFHSISPLNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ2</accession>
    <name>A9AVQ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4020"/>
    <dbReference type="EnsemblBacteria" id="ABX06652">
        <property type="protein sequence ID" value="ABX06652"/>
        <property type="gene ID" value="Haur_4020"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4020"/>
    <dbReference type="eggNOG" id="ENOG50332BR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899473_0_0_0"/>
    <dbReference type="OMA" id="FRHQLAF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4062-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="35344" checksum="B406709F1E5F50B2" modified="2008-01-15" version="1">MSNWEKTFGKRDLPTPPAWVNFFNPQQWQDFRQIVERYLKNLGLPVRPENQGFVVLADHAGWSKDTRIGLSSLAQKCYAHPQSQWLAVITDHFEAMHKGFENEVLLQDEINDFESIRDLLAIRLWALEPELREKLIYREDLQDVCSVLVFDLPTTIRSVSSDEAMAWGKTNEELFAVALENLRGRELRLTEHELDDGINVLAITGDDFLIGSQSLLLEQYPQCVGRFGSLVAVPNRHVVLCYPINEPIALEAWTSMLPVVEGMYRNGPGSISNQVFWYDNGAFTHLPHSQEQQAVRLSPPTTFLTTFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU2</accession>
    <name>A9AVU2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4060"/>
    <dbReference type="EnsemblBacteria" id="ABX06692">
        <property type="protein sequence ID" value="ABX06692"/>
        <property type="gene ID" value="Haur_4060"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4060"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_8_1_0"/>
    <dbReference type="OMA" id="YLQFEAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4103-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="404" mass="44954" checksum="3C4F1EA7AB0987BA" modified="2008-01-15" version="1">MEPKTPEPIIKTIPSWRDLARWTITAFAIWLVAWLLWRTGNQLLPFVVGLVFAYLLLPLVNKLERWIPRWAAILVVYIVGLGIVTGSILYIVPPAIDQVNGFGKSLPEFYKNTLEPKINEGLKWYRSEVPDEIQEDIDKQVSKGITTLKENATNYVETGVNGILNGLGVIFQTIIFLAGFLIIPFWLFYVLLDERKGKAALIRMIPKAVRTDVLTVLSIFDRVFSAYIRGQLTLGLIIAIMSYIGLWIVDLVMPGEIPYKLLLALVAGFTELIPVIGPIIGAIPAVIVGLTTSLPMGLVVAGLYIVIQQIENNFLVPRIIGAIVEIHEAVLMLLLVIAGTVSGLLGVIIFAPMAAVARDSYQYITGRLRQPNDPRYLRAGELPWEHKEEPETPMPPMLALQNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW1</accession>
    <name>A9AVW1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0551"/>
    <dbReference type="EnsemblBacteria" id="ABX03199">
        <property type="protein sequence ID" value="ABX03199"/>
        <property type="gene ID" value="Haur_0551"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0551"/>
    <dbReference type="HOGENOM" id="CLU_1903816_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-560-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14335" checksum="624A5A62443FA60B" modified="2008-01-15" version="1">MAVMLSLTIGGEVKEIRKLPFRQNQDFKKKLIDVAKKVMPQVDQMSKPPATNEEGKQSGEALTAYIVTMLESVDGLLEDALSLIIAYASGAIPKSIDDEILDEEIIDAFLCIANAAVPIKKLQVLAAGFSSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW03</accession>
    <name>A9AW03_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator receiver sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0593"/>
    <dbReference type="EnsemblBacteria" id="ABX03241">
        <property type="protein sequence ID" value="ABX03241"/>
        <property type="gene ID" value="Haur_0593"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0593"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_72_0"/>
    <dbReference type="OMA" id="TSTRHMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-602-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="176"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="397" mass="43906" checksum="363B77F4E64F561D" modified="2008-01-15" version="1">MAGSTRVLYIEDNHDNQRLVRRVLATRGYQIIIANDGNEGWKSAQTDRPDLILMDINLPGLNGYELTTKFKATPQLASVPIVALTANTTPGDRERALAAGCDGYISKPIDPRALPDLVASYIGGTREVLETAEAPSVMREYSQQLVGRLESHVRELETANNRLTRLDQAKNDFLATISHELRTPLTVIHGYIDLLNMQALGPVSDGQREALELMKRNSTRLLRHINDLIYLQQVRSNQMDFAQADLRGLVQSICNDMQPTFLEKNQTLVRNIYVSGIQTPLMIHMDVHGVDNAVRHLLENATQYTAQGGVIQVSVYQDDQLVRVSIRDNGVGIPEDDFERIFEPFVRLDDTLASIGGAGLGLVIAKHVAEAHNGTVSLESTVGVGSIFTLQLPVNHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW32</accession>
    <name>A9AW32_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0622"/>
    <dbReference type="EnsemblBacteria" id="ABX03270">
        <property type="protein sequence ID" value="ABX03270"/>
        <property type="gene ID" value="Haur_0622"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0622"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_0"/>
    <dbReference type="OMA" id="NRFQMND"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-631-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="35"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="35986" checksum="E28E622EEF462695" modified="2008-01-15" version="1">MKHVQEIAQRVAANVEKVIIGKRAAVDLTLIALLCRGHVLLEDVPGVGKTTLAKAIARSIGCSFKRIQFTPDLLPTDVSGVSIYNQKSGEFEFRPGPIIANLVLADEINRATPKTQSALLESMEEGQLTVDGITRALPQPFIVLATQNPIEYEGTFPLPEAQLDRFLLRITLGYPAKADELAILESQRKAHPIDALAQVVSIEELQHMQSEIRDVYVDEQIKEYIVAITTATRNNSDVYLGASPRGSLALYRTAQALSALQGRDYVIPDDIKVLVKPVLAHRMIISPAARIRNIHADELMQQILSQVPVPGARAGRRYERQQPAAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW41</accession>
    <name>A9AW41_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the globin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0631"/>
    <dbReference type="EnsemblBacteria" id="ABX03279">
        <property type="protein sequence ID" value="ABX03279"/>
        <property type="gene ID" value="Haur_0631"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0631"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_13_3_0"/>
    <dbReference type="OMA" id="MQRGWET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-640-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="3">
        <location>
            <begin position="19"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14311" checksum="861F02930193E758" modified="2008-01-15" version="1">MQQTFAEVGRNPQQLVEAFYGQLFMLAPDFRPLFPEDMSEQKKKLLQSLVLVVNNLKKPEAVLPAVQELGRRHVDYGVKPEHYQTVGAALIWALSQQLGEQWNDEVQAAWVAAYTLVANVMVEASQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW47</accession>
    <name>A9AW47_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0637"/>
    <dbReference type="EnsemblBacteria" id="ABX03285">
        <property type="protein sequence ID" value="ABX03285"/>
        <property type="gene ID" value="Haur_0637"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0637"/>
    <dbReference type="eggNOG" id="COG3361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102511_0_0_0"/>
    <dbReference type="OMA" id="HYWGYTK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-646-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018644">
        <property type="entry name" value="DUF2071"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39186">
        <property type="entry name" value="PTHR39186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09844">
        <property type="entry name" value="DUF2071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="27253" checksum="C7C07EA13A79BE9D" modified="2008-01-15" version="1">MKIAFLSAQWANLGLFSYAVPDQLLQPYLPTGLELDRRDGSAFVSLVVFDFLQTKVLGLAWPGFRNFAEMNLRFYVRRGQQRGVVFVREIVPQWLVATLANVIYNEPYVAAPLQSHTQQSASHITVEHNLYWQGQTNLVKLTASKQLYHPAADSTEHFFKEHEWGFGRKRNGQPIIYRVEHPEWDVYPVERYQLQFDWGAIYGPQWAWLAQETPYSVVLAKGSAVKVFPHQRMPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR0</accession>
    <name>A9AWR0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0663"/>
    <dbReference type="EnsemblBacteria" id="ABX03311">
        <property type="protein sequence ID" value="ABX03311"/>
        <property type="gene ID" value="Haur_0663"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0663"/>
    <dbReference type="HOGENOM" id="CLU_1967518_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-674-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="13652" checksum="72467570320D90CD" modified="2008-01-15" version="1">MSRFTPTTTIDLTDAEDTITMRTGLTYGQRADYADALMQIEGEYVTTYRRQLLMLEATIEDWSGPSFDAMPLTRTSIAALDARDPLVQRAVAHAEAVIYPKAAPLTDDTSSTASATPSSSTGVGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU7</accession>
    <name>A9AWU7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein, Crm2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0700"/>
    <dbReference type="EnsemblBacteria" id="ABX03348">
        <property type="protein sequence ID" value="ABX03348"/>
        <property type="gene ID" value="Haur_0700"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0700"/>
    <dbReference type="eggNOG" id="COG1353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012640_1_0_0"/>
    <dbReference type="OMA" id="EFYAAWV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-712-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038242">
        <property type="entry name" value="Cmr2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024615">
        <property type="entry name" value="CRISPR-assoc_Cmr2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013407">
        <property type="entry name" value="CRISPR-assoc_prot_Cmr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12469">
        <property type="entry name" value="DUF3692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02577">
        <property type="entry name" value="cas_TM1794_Cmr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="338"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="616" mass="68549" checksum="6A3C094AE801EF56" modified="2008-01-15" version="1">MSHLLLIAIGPVQDFIASARRTRDLWFGSWLLSELAKAAAKSIYQAKGNLIFPYPTNPAQDLAPESAFNVPNKILAKVEGDIKKIADTAKQALEQRLNQIRDGAFDQVKGTFYDEQAADQIAALVEFNWVALPLGTDYAKTREQLEHLMAARKNTRNFSEVTWGTNAPKSSIDGERESVIDEKYYPPAGMANTSPEYAKIVARLYRDYGINVGERLSGVDMLKRHGQKGIDSRFPSTSHMAAIPMFNFLNKYDEANANISLIDPWNRYINFFNTNSTLIKYIDNERTPKSQKNFGNIDGSLLFAERFNDTLEGNDLSDAQNALEAFYTALGVKKRPIPYYAILHADGDAMGSVINNQEVIEKHQEISKALAKFADNKRDINPLNDSEERSVATIVAKHQGALVYSGGDDVLAFLPLHTALECADALAKRFQTLLSNFKDKTDRSPTLSVGIAIVHHLEPLSDALDLARAAEKKAKGFVGKNALAINLSKRGGADRIIVGSWIESKYSFYNRLKKLIEWHQTDQIPLGFAFELHDLSIRLKDLPANIFHAEAKRIIERKHTSNGIKVSSAIATELLAMINDLVPETLTQAHIMIQQFADEVIIAEFIADAQKLANGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV5</accession>
    <name>A9AWV5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ordered locus">Haur_0708</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0708"/>
    <dbReference type="EnsemblBacteria" id="ABX03356">
        <property type="protein sequence ID" value="ABX03356"/>
        <property type="gene ID" value="Haur_0708"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0708"/>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060296_1_0_0"/>
    <dbReference type="OMA" id="IEGPFRD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX03356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="302" mass="33589" checksum="243EC1B847504423" modified="2008-01-15" version="1">MAQTSLEQTDLSPRREALQLWIPLGIVLLLTLVTAFLLTGQYQIAAGKGIVQGLGEPLPISSSAHLIVVPWFFDWQDPFFQTQTFDVALHMGTLIALLLFFWRDWLNLIMHMHQPRSQQGRMFWFIVLASIPAGIVGLLLDSLAEEYFLDKYLVIAGTMSIMGVVLYIADRFAPRRYELSDLTWKHALLVGCAQALALIPGVSRSGSTMTMGRALGFTRETAARFSFLMAIPITFGAGVLKLRDIDSSQLTAPFWLGISVSFVVGALAVGFLLRYVRTNSFLPFIIYRLVIAAVIVAVYLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW4</accession>
    <name>A9AWW4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0717"/>
    <dbReference type="EnsemblBacteria" id="ABX03365">
        <property type="protein sequence ID" value="ABX03365"/>
        <property type="gene ID" value="Haur_0717"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0717"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_332275_0_0_0"/>
    <dbReference type="OMA" id="NYAGAPT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-729-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="41"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="563"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="861" mass="95275" checksum="82C256466A25B461" modified="2008-01-15" version="1">MVCPRCSTELKTGARFCPKCGAGLPRWTGRLANGDVLIDRYVVVRPLARGGMGAVYLATDRRLGDAPVALKEMTGLHQPGDTDAWERAVGEFRREASLLARLSHPNLPRVIDQFRHDENEFLVMEYVEGQTLRAEMEGRAEPLALETVIDWMRQLTNVLQYLHNQNPPIIYRDLKPPNIMLRPDGRIALIDFGIARLFKHGQEGDTVIYGTPGYAPPEQYGFGQTDHRSDIYSLAMVIHELLTRFEPAKRESTRPPLAHNLRNTVPPALSEVLHRAMHPDPADRYQSMRDFQMAVDNSLNQNQVAALPDATVLHQATIAKPKAANWWWLALALVGLGLIGFLLARTFGVFSPEVQPTSVAQITPSLAEPTPIEATAVPIVIGPAPPGMLAIPGGTFVIGSDAGSPNEQPVGRGYLPTFYIDRTEVTVAAYRACVEQQRCSEPVDRSSLTVADYYDNAQYAEYPMINVSWQQALTYCQAQNKRLPSEAEWERAARGAEGRIYPWGDQWDASLLNAWGAGVAGDTQAVGSYPNGATPEGVLDLAGNVWEWTSSLDLPYPYNAADGREVPTQPGSRIVRGSFSGTNPENARAAVRERRDPELPLNIIGFRCVTNDFYVPEGMDFIAGGRWTMGATAEDLAHYKEVYDWQGLQNEEPATPISTTAFYLDRTEVTNQAYAEFINATDRAAPTNSFDPVGLSLWLPDRTVPISLSQHPVVNVTWDDARSYCEWRGKRLPTEAEWERAARGDQRTIFPWGDQADASLLNNKDFGPGRTMPVGTLPNAGPYGTLDLAGNVWEWTQSLYIPYPYHPNDGRELPTGAGSRVLRGGSWFDDLMSAHTTGRNSFRPDLANINVGFRCAQDVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX98</accession>
    <name>A9AX98_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4186"/>
    <dbReference type="EnsemblBacteria" id="ABX06818">
        <property type="protein sequence ID" value="ABX06818"/>
        <property type="gene ID" value="Haur_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4186"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007196_0_0_0"/>
    <dbReference type="OMA" id="FQVEEGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4233-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010768">
        <property type="entry name" value="GATase1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07090">
        <property type="entry name" value="GATase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="386"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="828" mass="88726" checksum="A938C24172704DE3" modified="2008-01-15" version="1">MIFLGLFLVIGLSGWWIARKTTLDWRVVGLRLTSLACILLALALPRNQANQQASPLILLVDQSANLPSELRDAAWNEAVRFYQQQIEQRPVRLLAFGADVRVSQTDQRPAIDPNGSDLAGALQFASGLLPQGGDIILLSDGASTTTNGQNQVSTFAQRSIRLHGVPISYPETDIRVESLLVPPALREGERFSADVVLYSSVDGQVRLELSSDGVGLAGQTINVEQGRNLVSFQSTAGARGFHRFQATLLATNDQQPANNQLDAWTVVGPPPRVLIIERSPDSSANLRDALEAANLVTEALRPAALPTSLSQLRVYDSIVLQDISANDLSLDQQLALREFVRSLGHGVVVLGGTNSYNLGSYAGTPLEELLPVSMEPPPRRERPTVTLLLILDRSASMLGESGKDKFSLAKAAAIAATDSLGADDTIGVLAFDDTNDWTVTFTKVGQGVQLSEIQNNIAGLSAGGGTDIYAALEVGMGGLAQQTGKVRHAVLLTDGRSGGESSYESLIAPLRAQGITLSTIAIGGDADTVLLESLAKLGAGRYHFASRPDDLPRLTLQEAEIARENPLTEGQFQANLATPHPAIRGLNLGEIPPFGGYVAVTPKPEAEQLLTTTEGDILLATWQYGLGRATAFTSDSGERWTATWRPWPNWGNTLAQIIAATYPNPARGDLRVSSELQQNQAIITLDAQAETGELYDLADVGLRVLAPNGSEQILRAPQIAPGRYQALADASQTGAYHILAALEQGPNRLETQAGVIHPYNREWAVSANPALLEQLVGLGQGQIGSLEQIAPSLQVANQTSNTQWWPWLIALALGLWVVEIAIRRGVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXG0</accession>
    <name>A9AXG0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4248</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4248"/>
    <dbReference type="EnsemblBacteria" id="ABX06880">
        <property type="protein sequence ID" value="ABX06880"/>
        <property type="gene ID" value="Haur_4248"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4248"/>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_7_1_0"/>
    <dbReference type="OMA" id="FIIGPHT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4295-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="13"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="43510" checksum="F75E41907B091E78" modified="2008-01-15" version="1">MSSTVQLILLLLVLIGVAKIGGALSAALGQPTVLGKLLAGVLLGPSLINVMHWETFQSSDLKSTIHYLSELGVIFLMFIAGLRIEAHELREAGKAATWTAILGVIIPFFGGLLSALAFGYGLIPAIFVGLLLTATSVSISAQTLVELGRLKSRVGTTLLGAAVLDDIIGLLLLSIFMATQTSDGNFMTIVWTIVRLVGFLVVAWFLGQRFLPRILERVKKMRTNEPVLTFAVLVVLGLAFTAETVGHLAAITGAFMAGILLSHTDVRDEIDRSISSFTYAVLVPIFFIGIGLNTDLSSLSGAAIPMAIMLCIVAIGTKIVGCGLGAKIAGLNQREAIQVGCGMISRGEVGLIVASLGVQNQIVDTNVFSLTVAVVLVTTLVTPILLKWSFKTEPLPSLHLALEPEDEVLAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI2</accession>
    <name>A9AXI2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0748"/>
    <dbReference type="EnsemblBacteria" id="ABX03396">
        <property type="protein sequence ID" value="ABX03396"/>
        <property type="gene ID" value="Haur_0748"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0748"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_0"/>
    <dbReference type="OMA" id="KMPERDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-760-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="26061" checksum="E3016FD30E65FC44" modified="2008-01-15" version="1">MQLDLTGRVAIVTGASRGIGRAIAEALAASGAAVVVNYRGSEAAAAEVVEAITAKGGKALAVQADVADPASHEILLKATTEAFGRVDILVNNAGITRDNLLLRMKESEVDDVLQTNLRGVMLLTKAVLRPMMKNKWGRVITISSVIGLTGNAGQANYAAAKAGLIGFSKSVAQEMASRGITANAICPGFIETDMTRNAMSEELINKALDRIPLARMGQPAEIANAVVFLASDAAGYITGQTLAVDGGMTMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI6</accession>
    <name>A9AXI6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acpP</name>
        <name evidence="12" type="ordered locus">Haur_0752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0752"/>
    <dbReference type="EnsemblBacteria" id="ABX03400">
        <property type="protein sequence ID" value="ABX03400"/>
        <property type="gene ID" value="Haur_0752"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0752"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_1_0"/>
    <dbReference type="OMA" id="CEIPDEQ"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 7 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="79" mass="8811" checksum="D2C775C98A0E0D5F" modified="2008-01-15" version="1">MSDLNERLKKLVAEQLGVEEDKIVPSATFLDDLNADSLDLVELVMSLEEEFGVEITDEEAEKLRTVGDAEAFIKANIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ0</accession>
    <name>A9AXJ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0756"/>
    <dbReference type="EnsemblBacteria" id="ABX03404">
        <property type="protein sequence ID" value="ABX03404"/>
        <property type="gene ID" value="Haur_0756"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0756"/>
    <dbReference type="eggNOG" id="ENOG5030SKW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2523001_0_0_0"/>
    <dbReference type="OMA" id="DVQILIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-768-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9339" checksum="5F00D32576ED98A8" modified="2008-01-15" version="1">MTLDEAKTELTNLVLGVSPDAVLRYKKRGSDELAIRVYAPADHEDAIRDATRERSIALLTEHDLDVQILIYDISTSLPTEEGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ0</accession>
    <name>A9AXQ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03464">
        <property type="protein sequence ID" value="ABX03464"/>
        <property type="gene ID" value="Haur_0816"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0816"/>
    <dbReference type="HOGENOM" id="CLU_1439270_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-829-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20984" checksum="FD88C1F4FB183F9B" modified="2008-01-15" version="1">MSIMILLVLGLCVLGFYIHVGIIFNRVVQLAQQRSDLRTSAWLLLVNLAEPFIMGVWLLIQLIYFDFESLIGSVGEPLAATSSFFTYYWPMALLLIGIPVIALLFIPQAQVRATAIRSLWTGAMRLVMVWLCFNFIMVGATILIAIGLSIWSLRLINSYYKSLMAQSSLAVVFDQHGLAIQAIVPSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS8</accession>
    <name>A9AXS8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2254"/>
    <dbReference type="EnsemblBacteria" id="ABX04894">
        <property type="protein sequence ID" value="ABX04894"/>
        <property type="gene ID" value="Haur_2254"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2254"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2282-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="30"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1442" mass="161987" checksum="AF1397839681B4C8" modified="2008-01-15" version="1">MMTTPNTQVLHEAANQRESARLLQLRLTGFVGRQAEQTAIRGLIDQTRPSGGYVLVTGEAGAGKSSLLAQLIVNAGLDQTPQHFIALTPGRAYQLDVLRSIVAQLLLKHDLASNYFPADSYPALRLEFGQLLQTLSARGISETIYLDGLDQLQPEVDGTRDLSFLPLQLPPGIVIVLGSRPNETIDSLALEHGVVYQVPPLHEQDAIGRWQQVQPTLEPALLHGLAQAVKGNALLIELAANVLRHTSTSEMLALLDHASADATNLFRLSLGRIEQAAPRHWQPLIRPLLAVLLITQEPLEPAVLAAIIERPTATVVEALTLMSDWVSVAADQRVALRHLLFHDFLIQHEFTQPELQVWHGRMTQWCGAALDQIWHDSTESVEQARRWYARQHYITHLDCAEQWEALWQVIDAGDYGEHKVRFEPSTRLYGLDLDRARESVIAAGQSIEQQLELLPRLWRYSLLRTSLTAHADQWHDDVFVILAMLGRVSEALAQIEICSDQVRQVLLWSRVVAYTEPELRLHIFQRMEQVARSLHESEERDYALHLVAMAYADHGLLNMAYPIAISLGNTRDETLAYLVDVVIKQHDLARVKLIIGQIQTPKYRIKSSMLLANALIEETEFIEARQLLIETLPFAQNEQVVEIKSLLATIAWRLGDHQQADILLAEARSMHKYFADDAKIAALLAIIKGYLAQGNLAQAYNLHDEIKLNRFRRELVDIYINRDDIAIAVELAATITHWHSSDLAYAALVAWYCKEADFSKAEQALGLIKAPDQQIKSYCLLANSHADRFQWMRLLESAQLSLSSVISSISLAKCWLQLADAYAFQHAHDRAQSMFEHALTAILATSNSFLNDQMYDLLQLAHFAKRYNYDDLCQRVIYTTFLVGKHEDFEYSLPFEHAMLHLNHGEIDQVRQIIDTSVGPYVAVNLLQILIAESIKQQDHPQAQLYLFEALNHARKLENPSYRVSLLGELADIALASGFELLAKTILGEATQLLPVITAENEQRWAGVGLVRRYYSHGMLASAATITQVMTVSQTHDHIMVEISLCYADSGQLAQAYATLKVINTQTEVYARNLCQIIIKAHEHGLATLAAEYYDELIEAWSVIADPIRLLKDLKDLAIAQINYGSNQYLPSLLEAIRTIRHPALAEYQYVEVLCEIARAYIKQANYPDFADWLAYAHSIAQSIVIESRPKVAAYHYVAITYLCHATDSDTEIFLADMLRLANGIAPSSYANDLFNALANSCASYAVRGHPDFFAKAYQFAMAISVPWQRAQALRSVANGYAKVDDRVMVEMIIAEISRLSPNYLSLDAVALIYAQRGDLAFAQTLIANDEASEERDAVLDYLIPALLQTDAVVAAYQISHGFTRLTKRIKFLHQIVNYYVERGQIAESIQIIQAAWRNCGAAADLWELRTIVLPFDSTHPWLGTAVLDSVPWVEQQLARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXW3</accession>
    <name>A9AXW3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2289"/>
    <dbReference type="EnsemblBacteria" id="ABX04929">
        <property type="protein sequence ID" value="ABX04929"/>
        <property type="gene ID" value="Haur_2289"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2289"/>
    <dbReference type="HOGENOM" id="CLU_902466_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2317-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="33267" checksum="7E38D0EAE505C489" modified="2008-01-15" version="1">MSAPLLLMNQRELTKDELNLIQATIDRKTGNQTLQQSNTSIQQQSANKNTSNQATHSSISNPKLKLNEPRAIIIGAIITALATILVILKPFGLGSNDTFNYQVEVLDTSTNKPIGLAKVTITLPNLAPLEAFSDNNGFARLSIGDQYNDQAGILRLEKTGYDSVIFNVDIQADRLPKQIKLTPNQSNTPQPTATEAAAAATPETGSGIPTAGGATAPLLIGCWNNDSKPRNITNINIRESADGIKIGFKANCADSAITDEQDAVISAENEIRLSQVDETWTFSLRPDGTLRLAIEGQTGFEELTFYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY45</accession>
    <name>A9AY45_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4295"/>
    <dbReference type="EnsemblBacteria" id="ABX06927">
        <property type="protein sequence ID" value="ABX06927"/>
        <property type="gene ID" value="Haur_4295"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4295"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430714_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4347-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735101" evidence="1">
        <location>
            <begin position="23"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="635" mass="70693" checksum="B8BF52846EABC83B" modified="2008-01-15" version="1">MKRWIVLAIFVVGLGLPQATQATELQCFEQTGFCTDGRFLEYWRQNGGLEVFGYPLSTIDIVYNQDSQMHFLTQQFERARFEFHPEFAAPYDMLLGRLGDDLLRYRNIDSAMLPREAGATSGCLWFETTGHNVCNQANGLGFMSYWQNHGLNDPKLDAFGRSLQLFGYPLTEPAIETNANGDSVLTQHFERARFEWHPNQPDQFKVLLGLVGKESQKLVYGASADPSKLTLVGDTLFFTADDGVHGRELWTSDGTEVGTRLVKDLSVGTEWGGIYELAAVNQGVIFAVNKQDKDYQLWYSDGIEAGTRLIKSFVPNAKINNLKSLGNGIIFWANDAVHGIEPWYSNGTEAGTYLLSDINPGLADSAVSNNYGSYWVDYAPIAGGMAFFAQNNQIGNQIWWTDGSIANTRQISNLAISFGMLELEVLDQQHLIATAYQNTTMGVWNITLATGEQQLLASYPAIATTRNPASAIQLTQAGGKVYYLSKTQAGELSLWQTNGQADQTIQPNLQGYNAEHIVAANDQLYMRLTNPQGIQAGWWYFDSSQGLTQLTPLPLHIHAANNRLLGWESIAGGLRFYSTNGPNQALRYRSSVMGKQTYFPDTTNDRFFAIPSFQYGTELWSNDGSTLRMVKDIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY49</accession>
    <name>A9AY49_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cellulase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4299"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06931">
        <property type="protein sequence ID" value="ABX06931"/>
        <property type="gene ID" value="Haur_4299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4299"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_456264_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4351-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731717" description="Cellulase domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="3">
        <location>
            <begin position="42"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="662" mass="76589" checksum="930E969F0932C46E" modified="2008-01-15" version="1">MHKRLLPLVLALVLVVTPFLLANPATPAAAAEIPWGDKSTPFGMVVSLGNRVRSDEMPTMIRLMREAGVQWNREEIWWDQVQFEPDGPFRWDGDSSRFYNYDRAIQLQAEAGISILGLLDYNPAWFKGRNPHPEEWLSDWGDYVYATVARYGRDRGQIKYWEVWNEPNLVPSGYESGLYNVEDFVRVLQTASAAIRAADPEAKIVLGGVADIWSEIPEFAYDTPDYLQRLYALDAWPMFDILGLHPYRPDAPEVPVLRRDRTQTYREQAAEIDALLAQFGNKPIWYTEVGWSTESDGIVSEDEQAAWLQRFYLLAMTHPGVEKIFWYDFRNDTGDNSNYTRPINDPTENQFHFGLLRRTYPLNFDDQRIRKPSYSAYYHLTHNLGGLSWQANYAMPYDGGLGWQHWTNGDRSVDILWWLHEAQSPPYLEIHCDCSHVQVRAYDGTLLRVINTETGNVKIQPDQRGMPIWVEYGGYSRTGRTFDETPHSIIGGFRTYWEQNGGLARFGLPLTDELTEPGAGRIPTIVQYFERNRFELFPNNRPEFRVQLSLLGVRSLERNGVDWRGLPPAQNPPAECSYFVETGHSLCYPFKEYWEQNGGIAIYGFPLSEAFWEYDPVQNKGFLVQYFERNRFEHHPELAGTSYEIQLGLLGRQLYQSWAQYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY58</accession>
    <name>A9AY58_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4308"/>
    <dbReference type="EnsemblBacteria" id="ABX06940">
        <property type="protein sequence ID" value="ABX06940"/>
        <property type="gene ID" value="Haur_4308"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4308"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_516490_0_0_0"/>
    <dbReference type="OMA" id="YERRSRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4360-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="115"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="240"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="389"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="552" mass="61263" checksum="637EAD5AF3CA6D41" modified="2008-01-15" version="1">MDSYERRSRFVHRFATPLTTLNAGLALLERYLAESNANSAQIAEVMGLLNRSATRLGSAIDVLQEYMFDHPTGIQVIIPDEVLAQRPQHPVQTPTEQPNLALPKYPPDIDTSKPCVLLIEDSQTYRAVVSARLTQSGYNVVTAPDGMAGLDLARAYQPVAIILDLMLPHLNGEQVAFVLGEDPETKHIPIIIYTGLEAKQTEKLELDPRLQIIRKDEALDRLPIMVSELVIKSRKKTIAELLVIEDDQEIQQVVSQGLSNAGYSITVTTSGEEGLRLAMRQPFDLIMLDLMLPDIDGWTVLRQLRERTQTATTPLMLVSALGKPEEKVRGFQLGADDYITKPFDWNELLARISASLRRREVEGNANPSTMLPGNRAIERAIAARLDRKQPFVVGYCDLDHFKAYNDQYGFLKGDAIIHQTARIITGAVERSGAAGDFVGHIGGDDFVFLAHPDNVVAICESIIREFDQLAPLYYDIESRQRGFIRQNDREGNPKQFPFVSISIGVVSSLNHQITHFAEFGDLAADVKKRAKAHKGSVYLIETGDKATVNAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY79</accession>
    <name>A9AY79_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA binding domain, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06961">
        <property type="protein sequence ID" value="ABX06961"/>
        <property type="gene ID" value="Haur_4329"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4329"/>
    <dbReference type="HOGENOM" id="CLU_2649499_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4382-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="8869" checksum="DB2F17EC9D87E083" modified="2008-01-15" version="1">MSYLEEAHMRSHDYSIEEAAGLMQLSEDTVRRWVSKKLIGSYQLGRGWRISEDEIQNILTARHEMEQERQFAPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD0</accession>
    <name>A9AYD0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0864"/>
    <dbReference type="EnsemblBacteria" id="ABX03512">
        <property type="protein sequence ID" value="ABX03512"/>
        <property type="gene ID" value="Haur_0864"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0864"/>
    <dbReference type="eggNOG" id="ENOG50301BZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130269_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-878-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="22689" checksum="DC27F24CE13BD9A8" modified="2008-01-15" version="1">MHQPTTMTSNRGNFSFSRLMELLNGRWHKRASYAFLVIVAAHWAEHLSQAFQVYSLNWKLSEANGVLGMFFPWLISSEWLHYSYAIVMLVGLIVLRPAFQGRSRIWWNIALGLQVWHHFEHFLLLLQALLGTTFFGSPTRTSILQLFYARMELHLFYNIVVFLPMMVAMFYHVLPPIGEKTTPTCSCAWHQKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYK2</accession>
    <name>A9AYK2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2340"/>
    <dbReference type="EnsemblBacteria" id="ABX04980">
        <property type="protein sequence ID" value="ABX04980"/>
        <property type="gene ID" value="Haur_2340"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2340"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057821_0_0_0"/>
    <dbReference type="OMA" id="DFDDQQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2368-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="153"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="35162" checksum="24C392E96BC49B1C" modified="2008-01-15" version="1">MQLTGIHHLTAVTANVRENYRFYTQVLGMRLVKRTVNQDDVSAYHLFYADGAGTPGSDITFFDWPTPPEKRGTHSICNTALRVTGKASLEWWAEHLSQQAVKHSGLIERDGRLTIDFADNEGQRLSLIDDAGTGDANTPWDASPVPAEHQIRGLGPIRLSIPQLEYTDIVLTKALNMRQVRQYSLNEGNEYPVYVYEMGAGGAAAELHVVVQPDLAPAQPGAGGVHHVAFRTPNEAEYHGWTQRLRELSIRTSGEIDRYYFRSLYFREPNGILFEIATDGPGFAVDEDPATLGESVVLPPFLEPRRAAIVANLKPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYP4</accession>
    <name>A9AYP4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2382"/>
    <dbReference type="EnsemblBacteria" id="ABX05022">
        <property type="protein sequence ID" value="ABX05022"/>
        <property type="gene ID" value="Haur_2382"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2382"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313996_0_0_0"/>
    <dbReference type="OMA" id="WSCERAP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2410-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="22900" checksum="EAF21E734CB14ED7" modified="2008-01-15" version="1">MFGGAAATFGTGKHPRADCAAQWSALGNVAMVDPWVFGCSGQFAGPELFYWQPVAVAEGTMKIWLQIDATPGNLAGRAGLGLVIRQDDGAILRWAMQQAPADTNNVAEYQALVHGLRLVQRYYPQANVICLTDSLLIVDHLAGRCAVRTPHLHPLHSLACQLISRCVSFRVVHIRRAYNRLADALAWEALSGTKALVQWVNTPQEHLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ1</accession>
    <name>A9AYQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05029">
        <property type="protein sequence ID" value="ABX05029"/>
        <property type="gene ID" value="Haur_2389"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2389"/>
    <dbReference type="eggNOG" id="COG4325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032303_1_1_0"/>
    <dbReference type="OMA" id="YVQHIDM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2417-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018723">
        <property type="entry name" value="DUF2254_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10011">
        <property type="entry name" value="DUF2254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="444" mass="49593" checksum="4E91432FB468AE8E" modified="2008-01-15" version="1">MRITRELENQYHKLDSSLWFRPTLMAIGSAILAFFTVELDRVFDFDHVAFLRAGIDDARAILSSVTSSMLTVTTVTFSIIMVALVLASQQFSPRIIRNVMRDTPSQYVLGTFIGTFIYSLLVLGQINDQASFVFVPILSLATSIMLTLLSIVAFIYFVHHIAETIQASVLIARAAERTIDVLDRRFPETLGHAMEQIPPPPIPNETPTTIYNAKGGYIQAIDPVPLLELAQRFDVVIYMDRAVGDFVPTGNPLLHMVPQRELDPDSIAEFQDVFEIGLERTLFDDVLFGIRQLVDIALKAISPAVNDPSTAINAIDLLSDVLAQAIRRPEQSPCRYDEFDQLRVVANTITFRQMLGTALNQIRQYAKGEIAVTARLLVLLNEVALACNDQERRAMLWEQACIITRGADQAITEPFDRAYINEHLLTLANTLAIASEQRITLKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV2</accession>
    <name>A9AYV2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophanate hydrolase subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4360"/>
    <dbReference type="EnsemblBacteria" id="ABX06992">
        <property type="protein sequence ID" value="ABX06992"/>
        <property type="gene ID" value="Haur_4360"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4360"/>
    <dbReference type="eggNOG" id="COG1984">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028967_0_3_0"/>
    <dbReference type="OMA" id="QDLGRSH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4413-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS2" evidence="4">
        <location>
            <begin position="23"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="312" mass="33731" checksum="D4AE6A5ECF69C173" modified="2008-01-15" version="1">MLTIRQTSMLITLQDAGRTGLRHWGMPASGALDWLAHGLASRLVGNTTDRASLEITAAGACLHFSQVTIISLVGADLGAELNDQPISLGRAWLVRPNSELRFTQRRVGARCYLAIAGGFNLAPQLGSQSTLLGAPWHGYLARPLHIGDQLTYTEPNLSLAGRSLDTASSISSQAPIRYLPNRQLANKLQRQFQAQTWQISSKSNRMGYRCEGPALAAPTQAVRSFGVVPGTIQLPPDGQPIVLLSDAQTTGGYPVLGVVIRADLPKLAQRLPLEYLQFQPIGVTLAERAFAEQLNILRANFELEPLILGTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX9</accession>
    <name>A9AYX9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A9AYX9"/>
    <dbReference type="STRING" id="316274.Haur_4387"/>
    <dbReference type="EnsemblBacteria" id="ABX07019">
        <property type="protein sequence ID" value="ABX07019"/>
        <property type="gene ID" value="Haur_4387"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4387"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_42_0_0"/>
    <dbReference type="OMA" id="QGIRVCT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4441-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="26498" checksum="1E0470648D9C8587" modified="2008-01-15" version="1">MEIQSLSVVVTGGASGLGGATVRRLYSAGAKVVIADRNIEVGEALAKELGSNAQFVACDVTDETSLAAAFDQAIATNGRLQAVISCAGVGSAEKILGRNGVHSLELFNRVIQVNLNGVFNALRLGAERMSQNEPNAAGERGVIINTASIAAFDGQIGQVAYSASKGAIVGLTLPAARELARHGIRVMTIAPGTFDTPLLAGLPEPARQTLAAQVPFPPRLGDPAEFAMLAQHILENPMLNGETIRLDGALRMGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ33</accession>
    <name>A9AZ33_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">leuC</name>
        <name evidence="14" type="ordered locus">Haur_4441</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4441"/>
    <dbReference type="EnsemblBacteria" id="ABX07073">
        <property type="protein sequence ID" value="ABX07073"/>
        <property type="gene ID" value="Haur_4441"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4441"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_0"/>
    <dbReference type="OMA" id="CNMSIEM"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="7"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX07073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="471" mass="50304" checksum="57D38C10FDCEEEDD" modified="2008-01-15" version="1">MAKTLFEKIWDAHVVQAADAESPATLYIDLHLVHEVTSPQAFTMLRERGLTVRRPAQTLATMDHSTPTTPRGADGIIPVTDAIARKQLDQLIKNCSDFGIPLYNLGTENQGIVHVIGPEQGYTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVGHVLATQCLLQQKPQTAEIRIDGTLRPGVTAKDIILAIIAKIGVGGGTGYVLEYTGSAIRALTMEERMTICNMSIEGGARAGLIAPDETTFAWLKDRPHTPKGEAWDAAVEYWRTLPSDEGATYDLQVVLNADELAPMITYGTNPGMGIPVTGNVPAPSDLADDSQRMALDKALNYMGLQPNQSLIGQKVDVVFLGSCTNSRISDLRAAAKVIEGKKVADGLRMLVVPGSQQVKRQAEAEGLDQIFRAAGAEWREAGCSMCIAMNGDQLQPGQYAVSTSNRNFEGRQGKGGRTFLASPLTAAATAINGHIVDVREIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZC8</accession>
    <name>A9AZC8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chloride channel core</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1026"/>
    <dbReference type="EnsemblBacteria" id="ABX03674">
        <property type="protein sequence ID" value="ABX03674"/>
        <property type="gene ID" value="Haur_1026"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1026"/>
    <dbReference type="eggNOG" id="COG0038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015263_1_1_0"/>
    <dbReference type="OMA" id="NPYYRVL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1043-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="421" mass="44673" checksum="425FFA575E320693" modified="2008-01-15" version="1">MLGTIITLMRQVGRWTGLALVIGFAAGVASAFFLVSLAWVTSLQTTNWWLLLSLPLLGGLVAWLYQRFGTSVAAGNNLIIEQLHNPDSAGIPLRMAPLVLLGTLLTHLGGGSAGREGTAVQMGASLAARIGRWWRLPQAEWRLVVMMGISAGFSSVFGTPIAGTIFAMEVLAFGVLRYEALLPCLVAALVGDGVVRWLNVAHSHYHVGSVPDLSMIWAILVGAGICFGLASSAFAIWTELVQTWSRRWLPNPILRAVAGGGLIVSISFLLNTRDYNGLSLPLLAQAFEPRGVVFWAFALKLLLTGLTLGVGFKGGEVTPLFVIGATLGSALAQLFGVPTDLLAALGFIAVFAGAANTPIACVLMGVELFGSALLGPLMLTTCIAYAISGHRGIYAAQRVGWAKRQHLAHQTSKRLDQLHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ4</accession>
    <name>A9AZQ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Glutamate synthase (Ferredoxin)</fullName>
            <ecNumber evidence="16">1.4.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Haur_4476</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="16"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4476"/>
    <dbReference type="MEROPS" id="C44.003"/>
    <dbReference type="EnsemblBacteria" id="ABX07108">
        <property type="protein sequence ID" value="ABX07108"/>
        <property type="gene ID" value="Haur_4476"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4476"/>
    <dbReference type="eggNOG" id="COG0067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_8_2_0"/>
    <dbReference type="OMA" id="TVFRLQH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4531-MON"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="15"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABX07108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1485" mass="160886" checksum="DD6B759A98B7E9FA" modified="2008-01-15" version="1">MNRLLYDPRFEHDACGIGFVARIDGKPTHATVSLALAALGSLTHRGGIAADGLTGDGAGLLTTIPRAFMARELAARRILANPQRIAVGMIFLPTSNTERARELIDDALVWRGLRPLGWREVPLDREQLGPIARDICPQIEQVWVDRPATMDDDSFERELYRARRRAERTALAENIDLYIPSLSCRTIVYKGLMLPSRLSLFYPDLADSDYIASAAVYHQRYSTNTMPTWSRAQPFRVVSHNGEINTLAGNVNWMRAREAHLSSPLLGNVRELAPIVDERGSDSAQFDNVLELLVRAGRDVRHSLLMMMPEAWEHIADLPQDVRDFYQWHANLMEAWDGPAAMTFCDGKIVGSALDRNGLRPARYIVTDDGLVVVGSEVGATPVDEDRIIRKGRLGPGQMIAVDLIKGQLLDNTAVKAMFAARQPYGQWLQNKSVDLAELVEAYTEAAVELNPDDLLRLQAAFGYTDENLAMVLKPMGREGAEPIGSMGDDTPMAVFSNLARPVYGYLKQRFAEVTNPPIDPLREQLVMSLSIRLGPRHNILLERPDQAHQIALASPILRNIELAALRACTDRSFGTATLDTTFPVTDDVQWIEHALDDLCSSADRALDTGATILVLSDREVAPQRIAIPTVLALGAVHHHLIRTGRRSTCSLIVETGEAHEVHHVAVLVGYGAEAVNPYVAIATIREIAKERSRTPITADQAEDNYVHSLEKGLLKVMSKMGISTVDSYCGAQIFEAIGLSDAVIARCLTGTPSRFGGADWQRLGRESYQRHAQAFGLEKPALSHPGLYKFRKDGEYHAFQPAVVHALQKAVRAAVDNGADFEAGYATYREYSDLLNQRQPSDPRDLLDFVATEPISIDEVESIETIVKRFSTAAISYGSLSAEAHETLAIAMNRLGGMSNSGEGGEDPERFGTEKVSAIKQIASGRFGVTPSYLMNARELQIKMAQGSKPGEGGQIPGNKVTEDIARTRHTTPGVTLISPPPHHDIYSIEDLAQLIYDMRTINPTAAVSVKLVSEMGVGTIAAGVVKGGADVVLISGNSGGTGASPLSSIKNVGIPWEIGLAETQQTLMINQLRDRVRVRADGGLRTGRDVVMAALLGADEYSFGTSALIAEGCVMARACHNNTCPVGIATQRADLRAKFPGKPEHVMAFMQFIAQEVRELLAQLGARSLNEIIGRVELLRQRQTNNPDHDALDLSPLLGLANAGPRRFNGMPQLVGIDRLNQFLVDSAFPSAKAGQEVIINAEITNEDRSTGITLAGELALLKNTGHVSMNFAGSAGQSFAAFATRGMQLNLVGDANDYVGKGLAGGEIVVRPRPTAQFLAHEATIIGNTALYGATSGSLYAAGRAGERFAVRNSGAVAVIEGIGEHGCEYMTGGTVVVLGSTGNNFGAGMSGGQAFVYDPNERFLGRLNDDMVIAERVESPLVADHLRELIERHAALTGSVQANDILANWEDQQGAFWHIMSKAAHAAAAQNNQPELAKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY3</accession>
    <name>A9AZY3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03690">
        <property type="protein sequence ID" value="ABX03690"/>
        <property type="gene ID" value="Haur_1042"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1042"/>
    <dbReference type="HOGENOM" id="CLU_1097416_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1059-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="28474" checksum="B3C7C274071F8B4A" modified="2008-01-15" version="1">MDENALPDPMLLTWMGSYTHADLHHVTRATQLLHHLAPFRDLSEAAVIGRWFTWLLMLEHHTLTYLDLNIEQAQRYWRGLRAVAEQRSAATSPLGQALGDFVGNLPRLPAFSSSDLMLVSLAIGHTLDGLAWRYSWQRQNSEPAASSLLDAMGRSSGMYTALTLLSGLRGWRLSEVLQQHPARRCIKVVEAVAGTLRLQPTSALPDNLWQALEQAFNPLETRWADYRQTSGLLLQRYQTWLTSDQSIADANAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZZ1</accession>
    <name>A9AZZ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03698">
        <property type="protein sequence ID" value="ABX03698"/>
        <property type="gene ID" value="Haur_1050"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1050"/>
    <dbReference type="eggNOG" id="ENOG502Z8RK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820598_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1067-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="38007" checksum="9567AD5F53D51EF2" modified="2008-01-15" version="1">MSIQAPISTAPTQPQQGWFAQILRHRGVQLTLVLWILGHGIIILLSNGALPFDRPAFAEIPFPLQILAPSVMMLEIFVLMGLGYMLTRNRPSIDLAARAPERSQAMRETLGLVAYAAFGQALGWVLGPMLGFQPLSFHLAGTLVGGHSGLSVAEVWVWAIYNFGFYAVVPYLWFRRRYSAVQLNLVSSNRRNDLLVIAVIAISESLFELTTLGTSLNRLSFGQLALGLPLSLFIYGIGTVLPTMILIYSILIPRFLKITGSAITTVLLGGLSYAIVHIAEGWTNFSTPTNALLSILFVLINYFGAGMIKTVLTLRTGNAWVHALGYHTIAPHVIIDTPHIVNIFGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B014</accession>
    <name>A9B014_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1073</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1073"/>
    <dbReference type="EnsemblBacteria" id="ABX03721">
        <property type="protein sequence ID" value="ABX03721"/>
        <property type="gene ID" value="Haur_1073"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1073"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120475_1_0_0"/>
    <dbReference type="OMA" id="ILWGGLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1090-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14225" checksum="D2A1E5C01F39E7A6" modified="2008-01-15" version="1">MATVMSAPSKPIIWTSRILRGLAAAFLLFDGSFKLFNPAPVAKSFAALGYPAGIALSLGILLLVCTVLAIIPRTAVLGTVLLTGYFGGAIASHVRVGDPLFSLVFPLILGGMLWGGLYLSDQRLRAIFPLREHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B022</accession>
    <name>A9B022_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multicopper oxidase type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1081"/>
    <dbReference type="EnsemblBacteria" id="ABX03729">
        <property type="protein sequence ID" value="ABX03729"/>
        <property type="gene ID" value="Haur_1081"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1081"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031740_0_1_0"/>
    <dbReference type="OMA" id="AVPNDMD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1101-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="130"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="261"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="373" mass="40991" checksum="A348220C693D281B" modified="2008-01-15" version="1">MDRNEQQPIEQVLNAPTSRRSFLRWTGMAAAAGTMVACGRESALTVEPATVPPASATTAAAGTDHSNGGHNSTGNAGTPTTDSGLKAWEEMDKMHEAGVKLFPAKTEGLSMQPLEYRMEGDVKVFELTCEKTMWEVEPGRKLEAWTYNGQLPGPEIRVTEGDKVKILVTNNLDESTAVHWHGLYVPNNQDGVPFITQPPITPGSTYTYEFTVRNSGSHMYHSHHNSTKQVSMGLLGPFIVEPKDKSKDPASDKEFILVLNDTAQGFTINGKGFPATQPLTAKLGQKIRIRYMNEGLMIHPMHLHGLPQLVFAKDGWNLPQPYMCDTLNVAPGERWDVIVDCTDPGVWAFHCHILSHAESEHGMFGMVTALIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A3</accession>
    <name>A9B0A3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonucleoside-diphosphate reductase subunit beta</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2574</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="3 4">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="181"/>
            <end position="202"/>
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        <location>
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        <ligand>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="342" mass="39532" checksum="DF362B116D98C308" modified="2008-01-15" version="1">MTEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIWRSTSLSADERLMVLRNLGFFATAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTHAFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAVLDPQFSTETLTGMQTFVKNLIGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAENPAIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGLAIQYGSQNPFPWMSETIDLTKEKNFFETRVTEYQSAASLEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="21621" checksum="865E6CBF486F0DA0" modified="2008-01-15" version="1">MHYQNMLCIGDSQTFGARSYGCYPLHLAQMLTQRTPYQWRTINRSVNGYTARNLWFKLNEEIDTISDTYQSCVLIGTNDVGNNTPIDLFEEYYRQIIRTLLIKGHKAVFCGEIPPIYADGHIFFTKETLERRKQYNAVVGKVVAEFSKAIWVSMVGLNRDCYVDPVHFNEDGNRRVAESFCEVIVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E2</accession>
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        <recommendedName>
            <fullName evidence="1">P22_AR_N domain-containing protein</fullName>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
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                <person name="Detter J.C."/>
                <person name="Han C."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05251">
        <property type="protein sequence ID" value="ABX05251"/>
        <property type="gene ID" value="Haur_2613"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018875">
        <property type="entry name" value="Antirepressor_Ant_N"/>
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    <dbReference type="Pfam" id="PF10547">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P22_AR_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="27663" checksum="5EA06F5A417DE81E" modified="2008-01-15" version="1">MQHFYNSDLGQLLALDPNQTYAAIPVICAMLEIPHAPQIKRIKAHATLAAGLRQLKVPNLDGEDERQACLRIDLIPLWAAGLDPNSVSAEAAPIIQALSSEMASVLWQSFRPQAFETNDQLLPNRWEQTQAEVAYRGALAVANLTREQMLLERQLTADVEAREMGGMSAEIEANAMLLARTVRRVAQVVGERSRRNEYPAIFDGLYRQWGITTYRRMPQARLNEALAWLERWYGDALGEPEPMPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0M7</accession>
    <name>A9B0M7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4614"/>
    <dbReference type="EnsemblBacteria" id="ABX07245">
        <property type="protein sequence ID" value="ABX07245"/>
        <property type="gene ID" value="Haur_4614"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4614"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064305_0_0_0"/>
    <dbReference type="OMA" id="WMRKIIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4671-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="160"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="35716" checksum="0024B275892A62BB" modified="2008-01-15" version="1">MANLPPWTIPLIIALVLFAAGAIIFRKLKETKSNSVDGRLATFAERNRSQTDSNERGMSALASRVDSMVNRGQKGSDLARDLAQADLKLTVTEFIMFKFGSVILFALFGVFLGRANFLAVVAGGVVGAIIGFIVPDKVVSFKQGSRLKAFNNQLGDTVGLLANSLRSGYSLLQSMDLVSREAPPPISVEFRRVVQEVGLGLSLEDGMNNLLRRVPSDDLDLMVSAINIQAEVGGNLAEILDTIAHTIRERVRIKGQIRVLTSQARYSGYVVTFLPISIAVIITMLNPDYMAPLMTIGMPPDAWCCMPVCSAMMMIGGFFAIKSIVNIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U7</accession>
    <name>A9B0U7_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_1169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1169"/>
    <dbReference type="EnsemblBacteria" id="ABX03817">
        <property type="protein sequence ID" value="ABX03817"/>
        <property type="gene ID" value="Haur_1169"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1169"/>
    <dbReference type="eggNOG" id="COG0564">
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    <dbReference type="OMA" id="MIITKSH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1191-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0003723">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
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    </dbReference>
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        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="75"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="312" mass="34467" checksum="5BC3948887CF9D4B" modified="2008-01-15" version="1">MPLWQLLMARLDLSPTLAQTLMVRGAIWINSVRVTDPLAEAPPEGELVVHTPPAGLYANPVVTPADILFEDEWILVLNKPAAWYSVATPWDTFGHLEGALQRFFLERDGEAVPFHLVHRLDHGTSGALIVSKNPSLNSRFQRMFNEGRVQKTYLALCSGLPDWTKLEVVTGHSRGEFGLWSVYPAAMIDQLYGPKDRRVRRAHTSFTVQAVGNAAALLAARLHTGRTHQIRLHAKHIGHPLVGDQRYGGVTQFGNLSIPDQLLHAAWLQFPHPRYGSMLELIAPVPSLWHVVGAAVGIDLQTGLLEEGHSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V6</accession>
    <name>A9B0V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1178"/>
    <dbReference type="EnsemblBacteria" id="ABX03826">
        <property type="protein sequence ID" value="ABX03826"/>
        <property type="gene ID" value="Haur_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1178"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_0"/>
    <dbReference type="OMA" id="AWLLKGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1200-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="77"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="31108" checksum="888A08C501B58D5D" modified="2008-01-15" version="1">MRIQRFFSRSFVHFAVITIAFLWTLPTVGVLVSSFRPENDVKTSGWWNALKHPFEESVWTFKNYSDVINANGIGEAFVNTLVVTIPATILPITVAAFAAYAFAWMKFPGRDWLFAMVIGLMVVPLQVALIPILRLYTQTGIAGTFLGLWLAHTGFGLPLAIYLLYNYISQLPADLIESAKIDGASDFTAFMKIVLPLSTPAIASFAIFQFLWIWNDLLVSLVFLGTNKVLTVKLSELTGSLGNKWHLLTAGAFVSMVVPLAVFFALQRYFVRGLLAGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z5</accession>
    <name>A9B0Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_2635</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2635"/>
    <dbReference type="EnsemblBacteria" id="ABX05273">
        <property type="protein sequence ID" value="ABX05273"/>
        <property type="gene ID" value="Haur_2635"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2635"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023176_1_0_0"/>
    <dbReference type="OMA" id="MYKGNAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2663-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735391" evidence="10">
        <location>
            <begin position="21"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="11">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="12">
        <location>
            <begin position="334"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX05273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="571" mass="61332" checksum="AC3026618E4CE931" modified="2008-01-15" version="1">MKRILIVALFVLCLWPSVAAAHALVIESSIVDGAVLDVAPAEVVLRFSEPLDRSYSSLTLYNEQSQPIGLPQTQFPAADSMQVALPAELRPGEYTLIYKVLSTADGHRSAGSLLFSIGTGVAPTAPSVEVSATANAGLNWGVVSGRSIALTGGLGAIGGLAWLLILLLPAIQHNPESRLPLLVRPTIWLTQLSLVWLLIGSVWEFVVRASDFGDGSLASIQYADVLSSMAISRWGVLALIRLVAITLLIPLTFLAAYQKPMGYVALALASLSLLTFSMSGHAAANIDDPITPVASDWMHMLTAAVWFGGLIGMALSAWVLRKTEAALRNSALAWLIARFSPLALFSIAMVVLTGTMRTFDQLPTLAGLWESRYGQTLLIKLAVMLAALLLGSWHWRKLNPRLQAAKDQTTVVKIGLTLGLESALAIGVILVASALTQTPHPVKAAPSAGGTARPTLPTPTPRVAQPLYLTAQREDLTMTLDTDDNRPGERQFSATVRDANGVIRPDRVRLRFESLDLEAGQQVAILEPATDGRFTATSGALSLVGRWKIEMQVRRLNLPDVTAEWTVEITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B144</accession>
    <name>A9B144_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2684"/>
    <dbReference type="EnsemblBacteria" id="ABX05322">
        <property type="protein sequence ID" value="ABX05322"/>
        <property type="gene ID" value="Haur_2684"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2684"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129722_1_0_0"/>
    <dbReference type="OMA" id="DQSCVKI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2714-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="14889" checksum="83F727F6D887AB6C" modified="2008-01-15" version="1">MRMAMPNKVITIQSDLDIVAARMAARDMAKAMGFGAIDQARIATAISELARNIYLYAGEGTVTVSEIQQGLRKGLQVVCEDQGPGIEDISLVMQDGYTTSKGMGMGMPGAKRLMDEFEIESVVGEGTKITCRKWKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B154</accession>
    <name>A9B154_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2694"/>
    <dbReference type="EnsemblBacteria" id="ABX05332">
        <property type="protein sequence ID" value="ABX05332"/>
        <property type="gene ID" value="Haur_2694"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2694"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_5_2_0"/>
    <dbReference type="OMA" id="SLDYCTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2725-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="147" mass="14926" checksum="AECF77D69C9E1847" modified="2008-01-15" version="1">MSDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGMSFDDQTNEGDTEFFASGLRVIVDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCGSSFKPKNGEASASGGSCGSGAGGCGCH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B182</accession>
    <name>RL20_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplT</name>
        <name type="ordered locus">Haur_4638</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B182"/>
    <dbReference type="SMR" id="A9B182"/>
    <dbReference type="STRING" id="316274.Haur_4638"/>
    <dbReference type="EnsemblBacteria" id="ABX07269">
        <property type="protein sequence ID" value="ABX07269"/>
        <property type="gene ID" value="Haur_4638"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4638"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_1_0"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000122327" description="50S ribosomal protein L20">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <sequence length="118" mass="13440" checksum="DF1FD295730B6ADC" modified="2008-01-15" version="1">MARIKRGIMTHKRHKKLLNQAKGFRGSRSHNYKTAHEAVMKALAYAYRDRRNRKRDFRRLWIVRINAAARLNGLSYSNLINGLNKAGIVIDRRQLADLAVRDAAAFTAIVAQAKQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F6</accession>
    <name>A9B1F6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Multiphosphoryl transfer protein</fullName>
            <ecNumber evidence="6">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Haur_4712</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4712"/>
    <dbReference type="EnsemblBacteria" id="ABX07343">
        <property type="protein sequence ID" value="ABX07343"/>
        <property type="gene ID" value="Haur_4712"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4712"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_4_1_0"/>
    <dbReference type="OMA" id="EGHGVAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4769-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="13">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="14">
        <location>
            <begin position="162"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX07343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="825" mass="88448" checksum="4BE637396DFCDD21" modified="2008-01-15" version="1">MIELQQRHIQLKSQPANKQAAIQQAGQLLVANGQIESGYIQSMLQREALSNTYLGNGIAIPHGLPEARDLIRQTGIVVLQVPNGVQWNPGETVHLIVGIAARSDEHIAILRQLTRVLGDKTLVDQLTHTTNPDDLIRALTGAETAPAASAAPAISVAVASDQPFFETKVLNPTGFHARPATTFVDCAKRFQAEVRIRYGSREANGKSLISILQLGIPHGATIQVTAQGADAAAALRGLQQALAQGLADETAETLPTRAAVDVRWTPKAVEQTINGISAAPGLAIGLLRRYSHSELVIEDRPSDPMVEVNRFELALAAAQAELSTLYDEVQARIGSGKAAIFRVHSEMLSDTSLVQQTVSLLFEKHSAEWAWHQVISGRVAQIEKLDDQVLAGRAVDLSDVGQRVLRQLIGGDHQRPLNAATPVIILADDLTPSDTAAFDPDTILGFGTVRGGPTSHTAILARSLGIPAIVGAGEGLLNLPEEAIAILDGYNGKLYLNPSSADIEAATNLQAELAEQHERAQATRFEPAQTSDGHRIEIAANINRVADASVAAAAGAEGVGLMRTEFLFLERDSAPSEEEQFEAYRDMVQAMAGHSVIIRTLDIGGDKVVPYLDLPKEDNSFLGIRGIRLCLARPELFIPQLRAIYRAAAFGPLKIMFPMIATLEDWYAARDLAEQVRRELDAPQVPLGIMVEVPSAAVLAEQFAQEVDFFSIGTNDLTQYTLAMDRLHPQLASQADGLHPAVLRMIDLTAHAANAHNKWVGVCGGIAADARGSLILVGLGVHELSVSVPAIAELKAAIRQHSLADLQALAQRALACRSAAEVHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J3</accession>
    <name>A9B1J3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Arginase</fullName>
            <ecNumber evidence="3 10">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_1230</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + L-arginine = L-ornithine + urea</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1230"/>
    <dbReference type="EnsemblBacteria" id="ABX03878">
        <property type="protein sequence ID" value="ABX03878"/>
        <property type="gene ID" value="Haur_1230"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1230"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_2_0"/>
    <dbReference type="OMA" id="IATCFGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1252-MON"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX03878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="32991" checksum="48777D10286E276B" modified="2008-01-15" version="1">MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGDLTLRYFEPIRDTLIQLASEVDQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDAHGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLANSMINPHRVALVAVRDLDPEERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGTPVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWHKQHPRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T5</accession>
    <name>A9B1T5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2739"/>
    <dbReference type="EnsemblBacteria" id="ABX05377">
        <property type="protein sequence ID" value="ABX05377"/>
        <property type="gene ID" value="Haur_2739"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2739"/>
    <dbReference type="HOGENOM" id="CLU_1233655_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2770-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="25920" checksum="102D00115054D391" modified="2008-01-15" version="1">MSEEPNQADQPQPPSANYGYQPYDQQQTYPSYNSQPSYSVPATTDNNTNAPNRWRRWVGYNALAFGLSCVIMPLGCCVMSVVANVLRSGLQELVDNPNFNLAGAIGVFVLLSFPLFLTIGVASMIQRAALYHQMPTKLWVFGSALSGIAAMFVAIMLMGMIAALFNLDFTPNAYILSIVGIFAGTSTGIGFFQWWQIRRVVINAWHWPLISGATWTGLGTLILGVGMSYLYNRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1U2</accession>
    <name>A9B1U2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ordered locus">Haur_2746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2746"/>
    <dbReference type="EnsemblBacteria" id="ABX05384">
        <property type="protein sequence ID" value="ABX05384"/>
        <property type="gene ID" value="Haur_2746"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2746"/>
    <dbReference type="eggNOG" id="COG0138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_2_0"/>
    <dbReference type="OMA" id="WRVAKFV"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="506" mass="53757" checksum="9CDEFA7F54C3898E" modified="2008-01-15" version="1">MRAIVSVSDKSGLADFAQGLSDLGIELFSTGGTKAALVGAGVPVRSVSDLTGFPEILEGRVKTLHPGVHAGILARRDKPAHLAQLAEHHIGQIDLVVVNLYPFAQTIAKPDVTLEEAVEQIDIGGPTMVRASAKNHAHVLIVIDPADYPRVLEALRTEQITPELRRQLAAKAFAHTAAYDSAIAAYLTDETFPQQLPLAWELAQSLRYGENPHQAAAFYRAPNAAANTLAKAVQHQGKELSYNNLLDADATLQVIQNFDQPTVAIIKHTNPCGLASAEDLVAAHKAARAGDPLSAFGGIVGVNRPVDRALANVLKKYFYEVIIAPSFSPEALTILAEKPNLRLLSVDTSRSSSNDWEYRSIGGGILAQHVDRVGNDRWDAWQVVTETVPSDEQLAALQFAWKACASVKSNAIVLVQGEELVGMGAGQPSRVDSVLTAIRKAGERAKGSVLASDAFFPKADGIQAAIEAGVSAIVQPGGSQGDDEVIAAANAAGIAMIFTATRHFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B226</accession>
    <name>A9B226_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4745"/>
    <dbReference type="EnsemblBacteria" id="ABX07376">
        <property type="protein sequence ID" value="ABX07376"/>
        <property type="gene ID" value="Haur_4745"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4745"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_0_0_0"/>
    <dbReference type="OMA" id="NYITSFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4803-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="26089" checksum="4584A353F94215C8" modified="2008-01-15" version="1">MISVPSHSVADQFDNIDLEALFEQMAPSYAQVSSLSSLGIISAWRKRCVATAQIQPGMVVGDLLCGGGEAWPWLEQAMQGQGSLIALDLVAQPLKYPILLERIEVHNCDMFANKLASQSLDRVVCCFGLKTFCYSELVRFAGEIRRLLRPNGRFSLVEVGTGNSWLSSLGQIYLQTIVPFFARSLGAPSYPYRQLAPLAQRFGDGRHVLQAFKQAGLQAEHQSIWGGLAHVFSGNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B4</accession>
    <name>A9B2B4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1311"/>
    <dbReference type="EnsemblBacteria" id="ABX03959">
        <property type="protein sequence ID" value="ABX03959"/>
        <property type="gene ID" value="Haur_1311"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1311"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098671_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1333-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="21151" checksum="ECEFB83E4D222DE6" modified="2008-01-15" version="1">MSLEHGIYTLREATTADLAGARQLMLRTFEQDFGYGYIAKWHADVDNLAEAYLDNPRQVLFVAVVRATNEVVGTCAVRTGGPKPPYKPEWLVERYSTVATAQIVRVYVDQAHRRAGLARRLVSLTRDWILHEGTYRTIYLHTNPAIAGAEQFWRSLPTSEIYDDRPDQGEFQNIHFEMDHTTPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G7</accession>
    <name>A9B2G7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1367"/>
    <dbReference type="EnsemblBacteria" id="ABX04012">
        <property type="protein sequence ID" value="ABX04012"/>
        <property type="gene ID" value="Haur_1367"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1367"/>
    <dbReference type="HOGENOM" id="CLU_487262_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1388-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="559" mass="60559" checksum="D9A25953A74D9D21" modified="2008-01-15" version="1">MQYAISLYDPFTNVQLARFDRQVTDATLSTNGLTASVRLAPFIAKTLYAQARLLTAVVQRNDGKVLRYRTVTLRLIDQGLAIECHNLIVTLDDLEYDGWWSVTKLDGWLPVETASSTPERWEMRHDDSTISLSPRKNEQFSNAKGIGRQSMFIPANLNTTGFQVIQFDWRFKGPTNWLATFLAAERDYSSQTGATTIALGNGTAQTGSMCFTFAARPLVSVAMYYNAALATYIGETGDDYLKISNLRVATVTTNMVNTTTSGAIAIGTAFVTVASTANIAVGQRLTIESGGANSESVVVLAVTATQFQAAFTKTHVLGSTVRGIVVTDKEIVEDVLSRNLTTNPGSGIKQSSARISKSSRDCLEAVWSAASGLSVVQELADQAQYVTYVDDAQYLYFGPKEVGRTFALVDGSIELEKALGEATNQVRFAYKNASNQPLYTAFAENASERYALGIVRQRTIASETTDATEAATLRSVALTDAAPTVRASLGVRAVRNEYNVREPLDLLSRGDVITIGDLSGAINKRSYTLAETSVNLVTGEVSVTPEAPIKQLDLWLAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M0</accession>
    <name>A9B2M0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2833"/>
    <dbReference type="EnsemblBacteria" id="ABX05471">
        <property type="protein sequence ID" value="ABX05471"/>
        <property type="gene ID" value="Haur_2833"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2833"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029469_2_1_0"/>
    <dbReference type="OMA" id="FLKHRWC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2864-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="212"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="47568" checksum="90EC35B0AF9A26DD" modified="2008-01-15" version="1">MVAPLSTLDELILHYVRALVALPSVTGDDPALEQAAPTIADILRGLGFQVNVHPTEGAPIILAHRPGKSAQRLLFFNHYDVMPAGVWRDWFHEPFTLAEREGLLYGRGVANDKGNLAARIAAVAQILAETGDLPVGVTFLIEGDGLSGSPSLANLVADQANHLTADLVVGYGGMLDQARLPYLYAGVRGRLLVRLRAEGAKIPIGADMATSVPNPAWRILWAVNRIKNDSEEVTIDGFYDAVVPPSREANKLTRGLQLDEETRLKAWGMPQFLFGMTGAGLARAETFNPTCNVAGLTVDTGHSPPPTIPASAEVLLDFSLVPEQRPTEVARLLREHLNSADFHDVHLEIIKGAYPPAMNALSTPLLNSLATAIEQVYGSTPQIVPLAPFSVPLHLFTAGMNVPAVALGIQRPDSNVRVINEHIQLADLKAMASLIQQLIIGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N6</accession>
    <name>A9B2N6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2849</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2849"/>
    <dbReference type="EnsemblBacteria" id="ABX05487">
        <property type="protein sequence ID" value="ABX05487"/>
        <property type="gene ID" value="Haur_2849"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2849"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_275307_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2880-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PTHR10795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735204" evidence="4">
        <location>
            <begin position="24"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="5">
        <location>
            <begin position="1066"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1160" mass="121550" checksum="70F3A4F3E2C43B42" modified="2008-01-15" version="1">MNRFLPRWAVLLSLLTLVISLFAQPLATTAQKAPLTTDYAPATSDSVAPVATPSHRLIIELQSPALAAWSKNTNKARNANQRLDLKAADAQTYLAQLEAEQNRFVTDMRQALPGASVERFVNEFGDLDELRYSVVFNGMTVNVGNTKRDDARKILEALPNVKGVYLDLPQQADLHVSNTLIGSPALWSSSAIGGRNNAGAGIKIASMDGGVHKDAPMFSGTGYSYPAGYPANGLGLTQNNNGKIIASRTYFRTWDGPADGDQNPWPGTNGTPHGVHTAGIAAGDVVTATFGGLNLPSTSGVAPKAWVMSYRVFYASVNGIGSFYNAEGIAALEDIVADEADVVNNSWGGGPGSIGGEFDALDTALINTSNAGIFVSMSAGNAGPNKGTSDHPSDEYIVVAASTTQATFAAGQLNVTQPTPISPTLQTIPIAAASFGGPINALVSNNYLPASVISPTNALGCSPFAPTTFTGKIALIQRGTCEFGVKALNAQNGGASFVIIYNNAANGNTLINMGAGAVGAQVTIPAIMIGFNQGTGLVNWYAQHGAASVAEINPSTYLAPSTADVIAGFSSRGPGVGDVLKPDVTAPGVNILSHGYTPGASGEARHLGYGTASGTSMAAPHVAGAAALLRQAHPSWTNDQIKSALMSTSKYIGVTVADGSPAQPLDMGAGRIDLSKASDPGVFLSPPSLSFGQVLTGTTKSILVTVTNATNVAETYNISTQYTGGGFNNITPMAGVTLASNTIAVPANGSAQFTVTFNSMAGRGYGDNQGFIVLDGPNHDAHMPAWARVTKPMANVDVLVIDNDGSASLGGAYIDVTRYYTETLEAIGLTYDVLDADDLAGSVTTFLPPAEQLYPYKAILYFTGNYNRRNGEFTVATPLTALDMDRLTEYANNGGTIIAMGQNLAQVLNSTSSTTESFFYSTVLSGEYVRANINSSNAMTVTSLITATTQAPQVFQTMEIDIDASETAGGGARNQTSVDALESLYGTDFDPNRDPLIRSLFSIEGEEDVTAGRLHRAQPSLETPGISYLGRTIYTTFGLEGVNNLGDTTSREALLETFFKVLWDDATSMIMPTSVGSKVWLDVDLTSEYDAVPVEYRWDFGDGSAYMTVPAGTPVAHSYATPGQVYTVRVEVTDSYGNKTLATRQVTAPWGVYLPVVTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P2</accession>
    <name>A9B2P2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Valine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Valyl-tRNA synthetase</fullName>
            <shortName evidence="7">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">valS</name>
        <name evidence="11" type="ordered locus">Haur_2855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2855"/>
    <dbReference type="EnsemblBacteria" id="ABX05493">
        <property type="protein sequence ID" value="ABX05493"/>
        <property type="gene ID" value="Haur_2855"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2855"/>
    <dbReference type="eggNOG" id="COG0525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_2_0"/>
    <dbReference type="OMA" id="FATKLWN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="8">
        <location>
            <begin position="29"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="9">
        <location>
            <begin position="644"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="10">
        <location>
            <begin position="857"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="855"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="554"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="921" mass="104396" checksum="D9FA6A4BB2F25C37" modified="2008-01-15" version="1">MSADKHLHNALAGADLGQAYEAAKVEEHLYKWWEAAGYFKPTAANTKAPFVIAIPPPNVTGVLHTGHGLTNTIEDILTRWHRMLGQPTLWVPGTDHAGIATQNVVEKQLAKVGKTRHDLGREDFLDAVWEWKGRSHSTITNQIRRLGSSVDWQRERFTLDEGLSQAVVVAFKRLYDDGLIYRGTRLVNWCPRCLSAISDLEVVYRDEQEQGNLWHIRYKVANDANDTEWRISEGDQSITIATTRPETLLADVAVAVHPEDERYADLVGKFVVLPALGRQIPIIADTYVEREFGTGALKITPGHDPNDYIVGQRHNLPILNAMNLDATINSEGGSYAGLDRFEARKRLVADLTETGNLVETKPHLMKIGRCERCDTIIEPLISTQWFVKTQPLAEPAMAAVREGRTKIVPERFNKIYFHWMENIQDWCISRQLWWGHRIPVWYGPDNQMFVELNAADAMAAATAHYGQVVELRQDEDVLDTWFSSGLWPFSILGWPDVENPDFKQFYPTTLLETGYDILFFWVARMMMLGLYLTGKEPFEWVYLHGLVRDEHGRKMSKSLGNQVDPMDLIEQYGTDALRFTFATSSTPGQDFALQPTRLDSARSFANKIWNATRFVISKLGDLPRTAESKVDAERLNAQAYTVADRWILSRFNRLAGDVERLMNSFNLGEAGRQIQTFFWDEFADWYIETAKIQIDTGDEQQQLRTRETLYSVLEGTLRLLHPFMPFVSEAAWQKLHNSEQTTPTPAALIIAEYPLINAAMLNEQAERDWDLVQNIIRGVRNVRTETGVEAVKWIEALIAAGSATAMLTEQTAIISRLARIAPDKLLISESLSERPEQATTLVFAPAEVVLPLAGMVDLAAERERLNKELERVEADVERRRTKLANENFVAKAKPEVVQKEREALAAQELAATTLRERLASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V1</accession>
    <name>A9B2V1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-1,6-bisphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3378</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FBPase class 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3378"/>
    <dbReference type="EnsemblBacteria" id="ABX06014">
        <property type="protein sequence ID" value="ABX06014"/>
        <property type="gene ID" value="Haur_3378"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3378"/>
    <dbReference type="eggNOG" id="COG1494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054938_0_0_0"/>
    <dbReference type="OMA" id="AVFYMDK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3415-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01516">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004464">
        <property type="entry name" value="FBPase_class-2/SBPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30447">
        <property type="entry name" value="PTHR30447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03320">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004532">
        <property type="entry name" value="GlpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00330">
        <property type="entry name" value="glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR004532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004532-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="35513" checksum="7D69F684C1474334" modified="2008-01-15" version="1">MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEGEKDEAPMLYIGEQIGNGSEPRVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGIVYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDVTVIVLDRPRHHDVIARIREMGARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRNDRERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRSASGTVRYIESRHRWDKLMRISDLPFAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E2</accession>
    <name>A9B3E2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1461"/>
    <dbReference type="EnsemblBacteria" id="ABX04105">
        <property type="protein sequence ID" value="ABX04105"/>
        <property type="gene ID" value="Haur_1461"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1461"/>
    <dbReference type="eggNOG" id="COG4719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_677515_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1483-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="406" mass="41933" checksum="2BEBD28DFF54808F" modified="2008-01-15" version="1">MEGVPAIDPRLNLTQRGGVITIGNTLGHDCAAGVPAPIVGAVGTCGTNTSDSGVDIYWRADSPAVSQAEANTSLNNAQARSSAMLNIPVGASVTHAYLYWGARWGGVTPTGATLEFNWGNSQNVTPISTVINPNSFYQAVADVTSYVQTHGSGAYRASGILANPFINTNDTNAFAAWWLVVVYADASQPNRTIILHDGLDQVLIGSSITNTLSGFNIPSSSTTNLTIVGYEGDNSSAGDQLLFNGNSVSNAQNPTDNMMNSTRSYLGNPVSSAGDLPQLTGAANSMGGFDLDTFDVSAWTSPGQTTASITTGSTSDMYFVGGLILAITSLVADTPTPSNTPTNTPTNTSTATNTPTNTPTNTATNTPTNTATATSSPTNTPTSTATNTPTPSLWRTFLPIAIRSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N5</accession>
    <name>A9B3N5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2969"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05607">
        <property type="protein sequence ID" value="ABX05607"/>
        <property type="gene ID" value="Haur_2969"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2969"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_3_0"/>
    <dbReference type="OMA" id="AHNWLFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3001-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735236" description="Alpha-amylase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="83"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="524" mass="57858" checksum="E340C25906E65CE8" modified="2008-01-15" version="1">MKKLLSGLLLAGVIVGCGGQATPTAVPATVTSQSTPTSQALNPTATAATVVDNSITPTPLPTKPTAPIFTADDERWAGRSIYFIMIDRFANGDPSNDNADGFGADRSDPRRWHGGDFRGIIERLDYIKGMGFGGIWITPVSKQNSTNAYHGYWQYDPYQIDPHFGTLEELRELVSEAHKRDILVMLDVVPNHMGDFLPGSKAAPPFDDPTWYHNKGNIQNYGNQQEVEDGDLLGLDDLDQDNPATRAELLKWIAWLKTETGLDGLRVDTAKHLPKDFLREFDQAANTFSLAEVFSSDAGYVAPYTEFNDAILDYPLHSAFKESLVGGRTLLVIQRVLENADQQYRNVHVNGTFLDNHDNERFLCLATGGPNADKTTQLRQALAVLYSLRGIPIVYYGTEQELNGCKDPFNREDAFELNATDVPVYQWISQLNQIRQAHPALQRGTLESRTTPSDAWAFQRTAGNDTVVVCINNTWKSLDLAVTGLTEIADGEVLTDALGSGQMSVKNGEMNCALQPKQVLIYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q4</accession>
    <name>A9B3Q4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Terpene synthase</fullName>
            <ecNumber evidence="2">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2988"/>
    <dbReference type="EnsemblBacteria" id="ABX05626">
        <property type="protein sequence ID" value="ABX05626"/>
        <property type="gene ID" value="Haur_2988"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2988"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042538_4_2_0"/>
    <dbReference type="OMA" id="LCDWGNW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3020-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="37550" checksum="21CA302112D16A88" modified="2008-01-15" version="1">MPNTAHLQQLARTVPATIPKLESPFPAQIHPLAAEVQQQTTKWVLEQGLLSEARRKAFLDYNYTLLIARCYPYASVERLQIISDWNAWLFELDDQCDEARIGHDPQALARLHQRLGAVIRGATVAADEPLLVTALADIMGRMRALAPLAWFEVFTQQVDDYFIGNQWEAHNRLYSIIPSEIEYLHYRKFTSAVAIYIAFIEFMNASYLTADERQSIDLRNLQNWTNLVLSLCNDLVSVKKELRQGDWHNYGAIVALKRGMSIPEALEIVANEHNHCIQQFITTTTQLKNCSVALQKVLNGMMTLMRGNYDWSDITSRYATKLTELSYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3V7</accession>
    <name>A9B3V7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3457"/>
    <dbReference type="EnsemblBacteria" id="ABX06093">
        <property type="protein sequence ID" value="ABX06093"/>
        <property type="gene ID" value="Haur_3457"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3457"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018249_2_0_0"/>
    <dbReference type="OMA" id="HAYMDSG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3494-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731870" evidence="1">
        <location>
            <begin position="28"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="618" mass="68753" checksum="892262A6CECE2355" modified="2008-01-15" version="1">MRQLFGCLCILIVVLSFSFSPRQPAQAAPMIEYRDPAPFSKAVKPTNTIAIRLGPSLTKAAVATVEFQVVGSRSGLHAGDVVLAEDQRTVIFKPASPFVFGETVRVSIKSSDIAELDQQTWSFEVVERLVKQTDQVKQLQTELAAELATQAKAAQPSGSSPVLRTVPFNLPPLTVTLAISNTPGYIFVSPFSWISNVTPNRYLMMVDNTGAPIYYKGLGSGRFSLDFRKIAEDKLVYFDTSTLSYHVMNQQYQELGQYRAGNGYQIDFHEFLMLPNGHVIFMIYDDIPYDLSPYGGEENAILTELVLQELDTAGNVVFQWRSTEHIPVYDSSHSLAGTAPVDYIHGNAIDVDTDGHWLVSSRHTDEITKINRQTGAVIWRLGGEGNQFLYLEDSPRFYHQHDIRRLANGNIMLYNNWNTLPRSPDSFSAALEYEIDEVAKTVRLVKRYRATPDYFATAMGNAQRLPNGNTGIGWGSIQPLYTEFNSQGQAVFELTAAAPMVSYRSMRFEWQGDPPWPPTLVTQSLANTTNLYYSWNGATEVADYQVFTGVTSTTLSLQNTTPKTSFETNTTVVNSDHCFAQVRARNSQGTVLGSSEIAFLASDTCTPNRMYLPALTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y0</accession>
    <name>A9B3Y0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06116">
        <property type="protein sequence ID" value="ABX06116"/>
        <property type="gene ID" value="Haur_3480"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3480"/>
    <dbReference type="HOGENOM" id="CLU_128155_0_0_0"/>
    <dbReference type="OMA" id="WNHRLTF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3517-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="150" mass="17725" checksum="F0A644DD7267B544" modified="2008-01-15" version="1">MIVDLSTRLDCAASTAIEHVTTSRLLEYVAKPLVTFVPKQPNQLPDIWRDGTYWVELRLFGLIPIGKQAIVISHPQQHPFTLRDNGHSPLIKRWDHTIEVAVEGTSTRYRDHVVVEAGWLTPFIWLFAQVFYRHRQRRWRRLAARHFRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D7</accession>
    <name>A9B4D7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0042"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02694">
        <property type="protein sequence ID" value="ABX02694"/>
        <property type="gene ID" value="Haur_0042"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0042"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_0_0"/>
    <dbReference type="OMA" id="WIAITEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-42-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="195"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="40724" checksum="6D514E56ED8BDB61" modified="2008-01-15" version="1">MKQATIALDLRVLDDHFPGIGRFCYELSLALLQTPIAEQLHLILPQQPRTQFDLRPLLQHPKVSRVSHSLFSVGQHREWRSLLSEIQADLAIFPYYIRPLFQPCPSLTLIYDTISWRVPATFSRRKRWQIAALHHVAIQQSAAIGTISHSAASDIAQFYGVNPQRLAYLGVGISAQFQPQPATTIAALRAKYGLPERYIVYVASDKPHKQIDFLLDAWQAAQTAEVGLVLGGRWRNPTSEQLLEHPKLHGRVWRIADVPEDELAALYSGALALAFPSLYEGFGLPALEAIACGTPVLAQNSSSLPEAVGAAGCLLPNEQATWIKALERMCHDSTWRESLAAQTSAQAAKFSWQQVAERLEQQLNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J2</accession>
    <name>A9B4J2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_1513</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1513"/>
    <dbReference type="EnsemblBacteria" id="ABX04157">
        <property type="protein sequence ID" value="ABX04157"/>
        <property type="gene ID" value="Haur_1513"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1513"/>
    <dbReference type="eggNOG" id="COG0592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038149_4_1_0"/>
    <dbReference type="OMA" id="YLIMPVR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1535-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="131"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="259"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX04157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="40309" checksum="2EF76F84E12854D0" modified="2008-01-15" version="1">MRLACLQENLKRGLALAGHAVAGRSSLPVLANILLATESGRLKLAGNNLEIGITALVGAKVDEDGAITIPAKLLSDLVGNLPNDTVELEVDPRTQTLTVTCRGTKANIKGIDADEFPAMAVPGNEPVLAYLPPELLRKVVSQVEVAAAAENTNPNPILQGVLIRLSGTQATFAAIDGYRLAVRTIELPEPAAYDTELVIPSRAMAELGRTLGDSETPIAMSITSNGGQVIFHSDTVDFVSRVIDGKFPDYERFVPPASNTSTRSVISTAEFSRAVKRIALFSQAAGNIVTLTMERGDGSEPGRLLLNANAAEIGESVEAISALIDGDDGKLALNVRYLQEALGAIDTDQVALETQTPNSPGVFRPIGGDEYLHLVMPMRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4L8</accession>
    <name>A9B4L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase, IS605 OrfB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04183">
        <property type="protein sequence ID" value="ABX04183"/>
        <property type="gene ID" value="Haur_1540"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1540"/>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_9_1_0"/>
    <dbReference type="OMA" id="INIECEG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1564-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="129"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="25398" checksum="574638DFF3F8B7CD" modified="2008-01-15" version="1">MVLVCHINRPDVELPTNQSVGIDVGLESFTTLSTGEKTEPPKFYRRSQKKLARAQRKLSRARKGSKNRLKARKRVANVHQKIRNQRADWLHKHALGIVQRFDMVCIEDLNVKGLARTKLAKSFSDAALSTFMQRLQEKAEWYGRRVIKVGRFYASSKTCHYCQTKTSLTLADRVWTCHTCGMTHDRDINAAINIVHEGLRLLAVGTTESQNAARDGVNPAKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q1</accession>
    <name>A9B4Q1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1573</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1573"/>
    <dbReference type="EnsemblBacteria" id="ABX04216">
        <property type="protein sequence ID" value="ABX04216"/>
        <property type="gene ID" value="Haur_1573"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1573"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_11_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1597-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="196"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="561" mass="62292" checksum="9E1CA2C539EFEEBC" modified="2008-01-15" version="1">MPIYNSQLLILNDGLQPVPDGCIGQIWISGAGVGNGYTGQPGLTAERFRPNPFDYIPGSRMYCSGDLGRRNQNGAIEFLGRTDHQVKIRGFRVELTEIAQRLQQHPAVREALVMRHEHPLRGEYLVAYVVLIQPAQADVGALRRYLAKHSPPYLVPAEIVLLEAFPLSPNGKIDRQALPHPTANVHAGEARQPAARSFDPLEFQIRTIWEETLGIEPIGAQANFFELGGHSLLAIALMARIEERLGKRLPITILFDAPTIEQMVGLLRQEGYAPRWSPMVLMQAGRKGFPALFCVHALSGSAFAYTVLPKHISPDQPFYGIESRGRDINQAPDRSIEAMAAYYIEHMRLIQPSGPYCIAGWSLGGPVAFEMAQQLYRAGETVALLAIVDTGAPLAGRLPIEPAAIDDLSLLVPRLRHFGINLDLDFIQALPADQQLPYIMQQAVSGGFWSANITLAEIKRKGELIRTNLAARRNYSAQPYPGTINLFRTKQHPGYSDDEVTLGWDQLALTGVKVWEIPGDHLSIFHSPYVEVLGHALWECLQGCTDQLDELDYAHERYRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S8</accession>
    <name>A9B4S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3013</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3013"/>
    <dbReference type="EnsemblBacteria" id="ABX05651">
        <property type="protein sequence ID" value="ABX05651"/>
        <property type="gene ID" value="Haur_3013"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3013"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="QEFNVDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3045-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31097" checksum="C150CED1B42F7CEB" modified="2008-01-15" version="1">MNAVEVRGLTKRYGNVQALQGVDLTVPEGMIFGLLGSNGAGKSTLIKALVGALKPNSGEWQVLGLNPLRDQAKLRALIGYMPQGVALYEDLSARENLRFFGSAHGVPALEQRIQEALEFTELTSRADHPVYGFSGGMKKRVSLACALLHKPRMLFLDEPTAAVDPHLKVRSWQLFRELANAGTTLFISTHLMDEALLCDRLAIQQTGKILIVDTPQAILEHGQTRLTIKQAEQTSEQQIASTPNALAETLHSYGLNPTIQALTLHPDSLETIVLRMLQKSEVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z8</accession>
    <name>A9B4Z8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-quinone oxidoreductase, E subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3083</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3083"/>
    <dbReference type="EnsemblBacteria" id="ABX05721">
        <property type="protein sequence ID" value="ABX05721"/>
        <property type="gene ID" value="Haur_3083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3083"/>
    <dbReference type="eggNOG" id="COG1905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054362_2_0_0"/>
    <dbReference type="OMA" id="VGKFHVQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3115-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="174" mass="19695" checksum="D8F71ADADFC1CB0C" modified="2008-01-15" version="1">MLYEQHKAEIDEILARYPVDRKRSALLPLLYLAQDVYGRLDRDSIREVAEILDLPYTDVFEVVGFYTLFYNEEVGKVVLDVCDDVPCCFCGAEELVADLENRLGIKAGETTKDKVFTLRRVKCIAACDQAPVLQANLEFHNRVLPDKVEAMLAKLRNDVESGKPVSISGRLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9B513</accession>
    <name>A9B513_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ordered locus">Haur_3514</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3514"/>
    <dbReference type="EnsemblBacteria" id="ABX06150">
        <property type="protein sequence ID" value="ABX06150"/>
        <property type="gene ID" value="Haur_3514"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3514"/>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032540_0_0_0"/>
    <dbReference type="OMA" id="CNFENYL"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="116"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="291"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="118"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABX06150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="46593" checksum="8C3018FD7180C10B" modified="2008-01-15" version="1">MLDLRNKRITVMGLGVHGGGLGVTRFLLEQGAHVIVTDLRSAEILQPSLEALAGLPVEFVLGEHRDQDFERVDMVIRNPGVPRESRYLQLARAAGVAIEMEMTLFFRLCPAPIIGITGTKGKTTTTTLTGAMLREVYPDTVVAGNLRVSALEQLPRITAKTPVVLELSSWQLEGLGEAGLSPEYACVTNLSPDHLDRYGSMADYGLAKQQIFLYQSPDDVVVLPKHDLIVNTWANDAPGRVIWFDGNEGWPMGQLQGQHNALNIAAAAALAQAYGVPDAAIRKAIEHFAGVEHRMELVREINGVRLINDTAATTPTAAAAALNSMTSPVILIAGGADKKLAWTPLVEAIQQSAQLKRLIILDGTGSPALSAALGTEQERYQSFEQAIRAAFAEAEAGDTVLLSPGAASFGMFRNEFHRGEEFRRIVGLLTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B578</accession>
    <name>A9B578_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3579"/>
    <dbReference type="EnsemblBacteria" id="ABX06215">
        <property type="protein sequence ID" value="ABX06215"/>
        <property type="gene ID" value="Haur_3579"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3579"/>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_544985_0_0_0"/>
    <dbReference type="OMA" id="NGWTAVC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3618-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="262"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="501" mass="56351" checksum="DA4391CC7D240A33" modified="2008-01-15" version="1">MLANTPQEEPTSQPDVFNSKWMKFAFAFLAIAGGAGVAAALAFFDNPLKLVLLFGGAGAAMVTMRNSEWGLLALVFMSYTRFSDVMVRNGAPSTAQPFLALLFLIIFLRWALYNQKPEPWLKPAAWIFVYGMVGVATFLYADDVMRVKNGVITYFKDAIIVIVVVMMMRSPKMLHRSMWALLFAGIFMASITTWQQLTGTFENDYLGFAKAGKMQIVSGVEDDYRIAGPIGDPNFYSQVLLTLIPLGMDRMWNEKNKKLRWFAIWQLSVCMASIFFSFSRGAFLSLSIASLIMFVRRPPKPLSVIIIIALGFVIIPTLPASYIARLETIPEAIPGLAQEDVRNEASFRGRSSAQQAGLRMFWANPVFGLGVGNFGNHYQEYARDLGLDNSRWDQAPHNMYLEILTEKGLFGLSVFSAMMWVLFRDMNRARKKFREINMGDFDGLIFGFQAGLVGYMFAGIFLQLSYPRFFWILIAIAYAIPNVANKAYEEYREALPNGETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D5</accession>
    <name>A9B5D5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0108</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0108"/>
    <dbReference type="EnsemblBacteria" id="ABX02760">
        <property type="protein sequence ID" value="ABX02760"/>
        <property type="gene ID" value="Haur_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0108"/>
    <dbReference type="eggNOG" id="COG3336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054944_0_1_0"/>
    <dbReference type="OMA" id="GMPFHAF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-109-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019108">
        <property type="entry name" value="Caa3_assmbl_CtaG-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09678">
        <property type="entry name" value="Caa3_CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX02760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="30298" checksum="A4AF5ED9A84A981C" modified="2008-01-15" version="1">MNDWTLDWPLLFGLIAATVGYLWAVGPARKRLGGPAAFPVGKAVAFLSGLLALGLSIMSPIGIWADRYLFTMHMVQHMILTMFCAPMLLIGIPEWLLRPLVQLPWVYSIVRFAVNPIVAFSAFNISFNGWHFPQFYDLALRNELVHILEHQMMMGSAILLWAPSLIPLPELRSSYPVQMLYYFVNSIIPTILGALITFADSVLYPTYELAPRIWGISAIADQQIGALIMWIPGGSIFILAITIAFFKWMNREDEEQSLPSIADQKAAARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K7</accession>
    <name>A9B5K7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1597"/>
    <dbReference type="EnsemblBacteria" id="ABX04240">
        <property type="protein sequence ID" value="ABX04240"/>
        <property type="gene ID" value="Haur_1597"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1597"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="MQTNYKE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1621-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="29"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="797" mass="88572" checksum="8CD24FBA4B2EE65B" modified="2008-01-15" version="1">MPLLPSQLPQYATRLIGRTRARTLVIDLLLDAQARLVTLYGQSGAGKTRLSLEVAEQVGEIFRDGRYFVALAPVSQAQFVLPTIAATLGVEESQHEAILDSLILALADKQILLILDNFEQVAGAASELLELIRRAPNLTCLITSRQALEVAGETAIMVPALQYPELGEDYQLEDLEQHSAIGLFVDRMRTRQPRFRLSADNAGALVDICRLVQGLPLAIELIAAHSASLTPQDLLFFVRNHLSMAALNPKQSARQAIIKPVLAWSVSMLPADAKDIFAQLGVFAGGATVETIKQVGLVETMPFESSLNALIDRHLLQTEQLPGQKARFIMIDAVHEYALEQLQKTGRLYYLQERHAIYYQILSETVHQNIRGADGAKWIEQLRGEIHNIRQAMIWSLDSSDGLVAQRIAGNLYFYWYRTSAYREAVAWLEQTYQHSNRSDLSAIARIATGLGGLLISLLRFAEAERYLIEARRLWQELGLPHDEISAIGNLAVLYGTLGRLHDSQLAFEAALALARKVGNQQREILMLHNLGTVAQERNQLATAQAYFEQALALKQQVNQTWDMFLTQINLGLVAVDQGRYAEAEQWFEQAFINAYAIGDHDSLAYIRYARGISAAEQADYVQAELHFRESERGWHTVGNLEGVQRSWLEQAALLIATANYAQAAEYLHKVEPIEALSQELQLRHIILATRLAIAIDDQAAMQHQAQRMLATALASELRRFDLTMLQHSAAVLVATQPTLAAQLLATAEQLRVERNLHQSVAEQQWLAQTNVARLVPTIALDLTAALQAAQASLAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M8</accession>
    <name>A9B5M8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2263 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1618"/>
    <dbReference type="EnsemblBacteria" id="ABX04261">
        <property type="protein sequence ID" value="ABX04261"/>
        <property type="gene ID" value="Haur_1618"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1618"/>
    <dbReference type="eggNOG" id="COG4295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_4_1_0"/>
    <dbReference type="OMA" id="AHRDPFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1642-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="DUF2263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014899">
        <property type="entry name" value="UCP014899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02452">
        <property type="entry name" value="TIGR02452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2263" evidence="1">
        <location>
            <begin position="10"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="29373" checksum="2F7F780AF6475060" modified="2008-01-15" version="1">MKREERKIIAQRTLDALAEGGYVNAAGQAVDIRAAQHAAEQASTIIWPDTALAEARNASQQPSINVYAATTLAAAQSHAQTGQRVAILNFASAKNPGGGFLGGSQAQEESIARSSGLYPCLTRCSEFYRFHKQQNDLCYSDALIWSPQVPVLCDDAGNWLEQPYLVDVVTMAAVNAGAIRQNHTGQSSEVEPAMRQRMQRLLAFCASQPIERLILGAWGCGVFGNDPAMIAKLFKAIIGQQAWPFAQIDFAIYDPSPRRATVALFAAIFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q0</accession>
    <name>A9B5Q0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-ubiquinone oxidoreductase chain 49kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1640"/>
    <dbReference type="EnsemblBacteria" id="ABX04283">
        <property type="protein sequence ID" value="ABX04283"/>
        <property type="gene ID" value="Haur_1640"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1640"/>
    <dbReference type="eggNOG" id="COG3261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_1_2_0"/>
    <dbReference type="OMA" id="HSLAFCQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1664-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="1">
        <location>
            <begin position="143"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="40609" checksum="19C2D71A9842E0AC" modified="2008-01-15" version="1">MVRDLCEALSLSYVLPLGPFHPDWQTPMRMVLRVEGEQIADVEFRDGYTNRGISERLTRTTIPQGLHLVSHICAADSHAHSLGFCLALEQLLKINASERAAALRLLACEVERATVHLSTMKEVLTILGLQRDAEHVQKLHHGLFEVMQHLCGTSSPPNYIVPGGVRQDLSSTEQESMALQFRRLERLMYRFVDRFIDHRGVLRRCVGVGVLSREAAEQFGVRGPMARAAGIGFDARIDRAYGAYAQFPPSRVTQERGDVYARLVIFSLEAFESLKLAIRVLANLPSGDWAGNAPDSVPQGSVTSNIESARGTLRYTVQSNGVKLTSVRIDAPRQFDRLIARTILAGMNIDDAPLIIASASACTACSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T8</accession>
    <name>A9B5T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1678"/>
    <dbReference type="EnsemblBacteria" id="ABX04321">
        <property type="protein sequence ID" value="ABX04321"/>
        <property type="gene ID" value="Haur_1678"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1678"/>
    <dbReference type="HOGENOM" id="CLU_828390_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1702-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="39631" checksum="FCF01326F3093B25" modified="2008-01-15" version="1">MKLINPTLPLFQKRAFEYFPQQLLYRIALYPGQHVRQLSLWMQKWLPVAPTYEVVQQAVTACLEWFLDHGDIQREFGASYRCMPAYVIGASSLNQPKLVIYGDPRIDQELKRRSFSLVQRLIYQHTHSPYPCGYERRVIGLDSANHQLIKQTLPWLELATLTQALPSIAELEVPDPQKARALTVEGVFEIYDPQFAQQPFYQAWRLKEQTNRRLNCLVRWRPTVDSPAYLTRYYYQHYPDALSALEYDYAVLWRWKIDAQTFPRQARWVEKLAHLQIPKGLPAQYWQWLQFLITEQPSADGDYWRLKLPLELCDEVRDVLTTRLGIQWRTTINQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B610</accession>
    <name>A9B610_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
            <ecNumber evidence="2">2.5.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3166"/>
    <dbReference type="EnsemblBacteria" id="ABX05803">
        <property type="protein sequence ID" value="ABX05803"/>
        <property type="gene ID" value="Haur_3166"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3166"/>
    <dbReference type="eggNOG" id="COG0294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008023_1_0_0"/>
    <dbReference type="OMA" id="EAPMNKS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3198-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="143"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="418" mass="45193" checksum="C2D372230382618A" modified="2008-01-15" version="1">MPEFAYNIRQYYPQQRQELLQMIAQIETYPNAAERVLTKANLIMLHCDQVDPHTAMIVKQELLALDGDALVSPHVYLGQSTQPTNLLAWANERSWRALCGKFQAIPLPALQALAQQIGALLLHNQARGSLKLGATQWDWGRKTLVMGIVNVTPDSFSNDGLLEVGTSQIQQQALEFAAAGADILDVGGESTRPGASSVSIAQEIARVVPAIQAIRHVCQLPISIDSYKAEVVAAALEAGANVVNDIWGLRQADGSWNTALAQLVAQANVPIILMHNRVSTVEQFAHGTNYAASDYGDIIGEVCAELRQSIDFALQAGIANDLIVLDPGIGFGKSPEQNLQVLRQLRTIASLGYPLLVGTSRKSMIGITLNRPVDQRLWGTAATVAYAIQAGADIVRVHDVAAMVDVCRMTDALVRHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B639</accession>
    <name>A9B639_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT</fullName>
            <ecNumber evidence="1">6.3.5.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murT</name>
        <name evidence="4" type="ordered locus">Haur_3614</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine = ADP + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57928"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:62233"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = ADP + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:59488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:143132"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+) = beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:62233"/>
            <dbReference type="ChEBI" id="CHEBI:143132"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a heterodimer with GatD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurCDEF family. MurT subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3614"/>
    <dbReference type="EnsemblBacteria" id="ABX06250">
        <property type="protein sequence ID" value="ABX06250"/>
        <property type="gene ID" value="Haur_3614"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3614"/>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041534_1_0_0"/>
    <dbReference type="OMA" id="WLWDVDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3653-MON"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140282">
        <property type="term" value="F:carbon-nitrogen ligase activity on lipid II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02214">
        <property type="entry name" value="Lipid_II_synth_MurT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043703">
        <property type="entry name" value="Lipid_II_synth_MurT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013564">
        <property type="entry name" value="MurT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08353">
        <property type="entry name" value="MurT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="2">
        <location>
            <begin position="57"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="MurT_C" evidence="3">
        <location>
            <begin position="335"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="463" mass="50549" checksum="CD62CA856E5A7EF8" modified="2008-01-15" version="1">MTIREHVALSVAQMAQWASRQFGFGGGTNLPGRIARRIAPDVLRHQTKRLSGGVVLVSGTNGKTTTSRMIAAICSQQGQPALHNRAGANLITGLTAATLDLGIWGQPHYQRALFEVDEAHLPAAIAETQPRVVLLLNLFRDQLDRYGEVDTLAAKWQKVLASLPSTSTVVLNADDPAVADLATGLQAQVLFYGLEDQRHGNDALRHAADSIFCRRCGQPYRYEPAYYGHIGRYHCPACGHRRPEPNVILRQLELDGTRGSTLRVIAGQNQGQQALELNLPLPGLYNALNALAAIAATSALNVPLPIIRNALEQFSAAFGRIERFEYQQKSVLMALIKNPIGASETVRMITSGSQAPLNLMIAINDKIADGTDVSWLWDADFEALAGHTQRIVVSGTRAADMANRLKYAGIDQHQLQVEPDLAQAFDLAIAGDEPLTMLPTYTAMLEMREVLVERGVLKPFWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B647</accession>
    <name>A9B647_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycosyl transferase family 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3622"/>
    <dbReference type="EnsemblBacteria" id="ABX06258">
        <property type="protein sequence ID" value="ABX06258"/>
        <property type="gene ID" value="Haur_3622"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3622"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007261_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3661-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="83"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="282"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="694" mass="72749" checksum="B762D3F6342C9482" modified="2008-01-15" version="1">MSASTTTSNLRRPLAWRIAQLTRSQALVLLSIILLCAGWLRLQNFAAVAEGNTYYTAATVAMTQSWHNFFFAAAEPGGSVTIDKPALGLWIQAIFGKLFGVSGTVVVLPQVLAGLATIGLLYWIVARRWGRSAGLLAAAIQAISPISIAVERTNNLDALLIVTLVGAMALFLVATERASTKYLLLAGAVVGLGFNIKMLQAFLPLPAFYAMYFFAAKTGWWRKLWQLGLTTPVLLAVSFSWAIAVDLVPASERPYIGSSDTNSVVNLILGYNGVERLTGREGQAMGGAIPTTDDRQRPNATDGNAQMPAMPNGNAQTPPNGMTDEGMRGQFGGQTGRTGGGGPGMDSGESGLFRMFSSPMNTNIGWLLGAALFAVVGLAAHYIKQRRWPDADVWGWAGWLVTAFVVLSFAGFSHGYYSATIAPAIAGTLAIGITVWRRSASKIVGLWLIGLVAAALVVQVIAAQPSVSGWLIPSVALGLALVAAGLAFRASWRVAATAVGIAAILLIPSEWAYKTSAMEQMNTTLPSAAAPTDNATGFAAGFAGNRNRSDSSSPSALATYLQERTSDTYYMLAVPSSMMGSSLVIETGRPVLMMGGFSGSDPVIDAADIAQLVADGKLRYIMTGGMGGAGRGGSSTVQTWVQQNCTAVTDAPNSQAGFDLPNGQMPNAQAAPTNGNTGGAQFAQNNSSLYRCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B693</accession>
    <name>A9B693_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GHMP kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3668"/>
    <dbReference type="EnsemblBacteria" id="ABX06304">
        <property type="protein sequence ID" value="ABX06304"/>
        <property type="gene ID" value="Haur_3668"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3668"/>
    <dbReference type="eggNOG" id="COG2605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048558_1_0_0"/>
    <dbReference type="OMA" id="NCTIDKY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3707-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001174">
        <property type="entry name" value="Galkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014606">
        <property type="entry name" value="Heptose_7-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036406">
        <property type="entry name" value="Hept_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00960">
        <property type="entry name" value="LMBPPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="5">
        <location>
            <begin position="94"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="6">
        <location>
            <begin position="235"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="36830" checksum="26F67C57482E8AB5" modified="2008-01-15" version="1">MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDLSAVSRAVTGREWDGKLSLPQAVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLLDTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFGGMAVQHFGGPQVIIERVATSEDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRGQIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPFSKRLQLEAALIEAGVTVRPFSFTKQGVHAWSVEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N8</accession>
    <name>A9B6N8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1704"/>
    <dbReference type="EnsemblBacteria" id="ABX04347">
        <property type="protein sequence ID" value="ABX04347"/>
        <property type="gene ID" value="Haur_1704"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1704"/>
    <dbReference type="HOGENOM" id="CLU_1945816_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1731-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021224">
        <property type="entry name" value="DUF2690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10901">
        <property type="entry name" value="DUF2690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="13618" checksum="34001DBCEB221970" modified="2008-01-15" version="1">MMIQSPVSTYAATCSGTGCNGKDPQASGCASGATTVATAYFTGGYVELRWSATCQTNWARVVSTSGNKYLKAYIVQQNVGELYASNVYGQSTYSPMKYAPTGQIYIQACGFMATQPNTDVGSGNCTGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z5</accession>
    <name>A9B6Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-alkenal reductase</fullName>
            <ecNumber evidence="4">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3226"/>
    <dbReference type="EnsemblBacteria" id="ABX05863">
        <property type="protein sequence ID" value="ABX05863"/>
        <property type="gene ID" value="Haur_3226"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3226"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_2_0_0"/>
    <dbReference type="OMA" id="WRYATEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3261-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="284"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="403" mass="41660" checksum="D2124F0204A9ECAF" modified="2008-01-15" version="1">MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALSEAPGNGLSDEQARIDLYKRVGPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNNHVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAAAVSKIAPMVFGNSREVQVGQDTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPLLNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSMLTISAQLAQELKLPVSQGALVTNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNGETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B734</accession>
    <name>A9B734_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3265"/>
    <dbReference type="EnsemblBacteria" id="ABX05902">
        <property type="protein sequence ID" value="ABX05902"/>
        <property type="gene ID" value="Haur_3265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3265"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_6_0"/>
    <dbReference type="OMA" id="GASHNDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3300-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732559" evidence="7">
        <location>
            <begin position="27"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="154"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="583" mass="60540" checksum="5FE882DC8F69FE8A" modified="2008-01-15" version="1">MKRLFVSFVLICSLVIIFSAPNPSFGQSRTPAKPVDRVDFAAPAVAGQFVVKFKATTSKANRSSALKALGAVQIDRIAALDAEVIEVASLKSNDTLAGREAVLAGLKQNPNVEYAEPNFIYNVNFTPNDPSQSSQWAWGVIRAYTGWDITQGSSSVVIAVVDTGVQGTHPDLDAKMVAGYDYIDNDSTPTDGNGHGTHVAGTSAAETNNSTGGAGTCPNCKVMPVRVLGNDGSGTLAGVANGITYAADNGAKVINLSLGGGGSTALQNAVDYAWGRGVFLACAAGNSNTSSTTSSYPAAYTNCFAIASTTSSDARSSFSNYGSWVEVAAPGSSIYSTWINSGYNTINGTSMATPHVAGLAGLLASQGLTNSQIRDRICSTSDRITGTGSTWTCGRINVYNAVNNGGSTPTPTPPTSTPNPTTPTVVPPTATPPPGGGSIVNGGFESGTTGWTQASSGGYNVIDTTRPRTGSYSVYMGGYNNASEGIYQTLTVPAGKSLSFYWYQTTAEGSTTAYDYLRVRVYNTSGTLLGTLATRSNVNTKNAWVAESLSLAAYAGQTVRIRFETTTDSSLITSFFVDDVSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q9</accession>
    <name>A9B7Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1794</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1794"/>
    <dbReference type="EnsemblBacteria" id="ABX04437">
        <property type="protein sequence ID" value="ABX04437"/>
        <property type="gene ID" value="Haur_1794"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1794"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_825785_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1822-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="38184" checksum="DD89B55AF532C535" modified="2008-01-15" version="1">MTTQFLPTEQIPGCPICQHPEARFVGHFPEPHIEEGLSVHQCLNCSIVYLNPRLTLEGIHMLEDSSEVYLYDAEQQAKAVHDREGIIAWLESMTQLKPGSILDVGCNRGYLLAAAARRGWQPFGVELSQVSAAEARQRFGLPIYSDLESLPQGQLFDLITCWHVVEHLHHPVQMLRQLGELLTPDGVVAIQVPAYRFADEYIRQGNGLHIFCASHPFHYTAETLTMVLEQAGLQVFYCDESPKYLFLTIYAAKPSRSINANQQAQLAAQREQTNQKLAWFEHDHAAIAQTLESMNAYVQHLETTLKTKNEHIAQLEQHLQTINNGRIMRILKRIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B821</accession>
    <name>A9B821_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3318"/>
    <dbReference type="EnsemblBacteria" id="ABX05954">
        <property type="protein sequence ID" value="ABX05954"/>
        <property type="gene ID" value="Haur_3318"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3318"/>
    <dbReference type="eggNOG" id="ENOG502ZUK1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_701645_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3355-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="393" mass="41735" checksum="4DFDF50D30F3DE44" modified="2008-01-15" version="1">MMNDQQQQSLLTAALIAGGIVGGVLGARSRRNHPKTLGEKVALLTENLRDQVEHRAADANSYLHSLNKQARKELKREQKKLRKAGKQANQRLNASLETGREQIGQAVDQMGKKVADGRDKGNALFGAATAGLAAVAAASRERASDLGDQTKSRLADVREQALDQGETLADKAKNIVAEVRERLSSTSESVLEQADDLRHRAVDVASSKSADARDQANDLVQRLSGIVQEFLATTTERAKEAREHAPDALRSVAQTVSAKAQDVSASVIPAVAGAASVVGERAKETASVVGERAKDAANVVGERAKETASVVGERAKDAANVVGETTQHAAQAVAHKTGEVATEVGRKGRRARTGLRSFILGIVAGLLTTPATGEQVRRDLRQKLETNLNRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B854</accession>
    <name>A9B854_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3351"/>
    <dbReference type="EnsemblBacteria" id="ABX05987">
        <property type="protein sequence ID" value="ABX05987"/>
        <property type="gene ID" value="Haur_3351"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3351"/>
    <dbReference type="eggNOG" id="COG0340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051096_3_0_0"/>
    <dbReference type="OMA" id="AVWKHIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3388-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="11"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="29781" checksum="B625B0216EF8B1E3" modified="2008-01-15" version="1">MLTSFEQTIIEPARYQLETLIIGQELLGLEQTASTNSLIRERAFAGVSEGLVIVANEQTAGRGRRGRTWSAPAGSSLLLSLLLRPTWLLPSESFLLTMLAAVAISEAIERETNCKVELKWPNDLLINGRKLAGILVELETAGPERLRWAVIGSGINVNWQPTEDPSINQAATSLALECGKDVDRAALLRAILQSYDRQYLSLRSGRREALRQAWLSRLTTLGQTVEVELSSHNFTGVAESVDQHGGLQVRSSDGQLHTVYAGDVKVRPVVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A7</accession>
    <name>A9B8A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06460">
        <property type="protein sequence ID" value="ABX06460"/>
        <property type="gene ID" value="Haur_3824"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3824"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3866-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="726" mass="80129" checksum="A2F6F397AD10CA1A" modified="2008-01-15" version="1">MQYPRLHQVHHKLVPQLKVHGTSFIISILQHNPKSQAGAPIEGSWNPNLASHLRNPALIRHAIVGPDQNLYIAGAFSNINNTAANGLARWDGSQWHSLATSGADVDRVQSMAFFNNKLTVGGAFRTWAGQPFAQLVQWDGADWMQLGSGFQGSFNNSPTQTTAVNALTVLNTMLIIGGNFTQFHGQPANGVVGWNATDAIPFGSANGQINMTVASTDTLMIHGDFRTFNNQTVPYGTIPSWKAGIWKILVLPAIPSGFIYKANLISIDQTIYLLANESYFNETFVFRWQNERWVQLGTGLPGQFTKLTNANGSLYLAQADGDGNANDSYGVVLRLVDNQWQTVNLPHSYTSISQLVAIGSDVYIIGLPAENQQCPNLVCTFTVERWNGTTLQLIGEAWQAPSIVSLVGDVDHVWATSRPTYLDRQAAPTVLFWNGQLWQGSSNTESFTTTIVPTLFKTADNSVYYTTRFEGSIDRQVWGNVWRLDRLTRTWNPNIDIGGWFGGWNTSGKDLLGSAGSVVMYSRPVDGVLRLRSNVWSEETSEFEVAGACDICVPFEVNGEFYQLVVRAQLQLIHWNGSSWDTLNSWENSYPVQLTSYPVVVWRGDFYLINGRKLQRYNLTTQMVEDIALLDGDGYSLATFTDQYLYVGGAFSSVNGIAAQNLARWNGTQWQALSQAPNGPVYVIATSPNYLYIAGNFSQVGTTNSLGVGVYHLTSSYQVFAPISNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B7</accession>
    <name>A9B8B7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3834"/>
    <dbReference type="EnsemblBacteria" id="ABX06470">
        <property type="protein sequence ID" value="ABX06470"/>
        <property type="gene ID" value="Haur_3834"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3834"/>
    <dbReference type="eggNOG" id="ENOG502ZBRT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090669_0_0_0"/>
    <dbReference type="OMA" id="ITIPWQI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3877-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="25608" checksum="4F75693753F0B1FB" modified="2008-01-15" version="1">MHGLMIFSGLFGALAVIFWFFGQPIWSLLNVPRQLNQLWQGVAVRRNHAIEHATVNVLEERYGSQLVDGCATTEGFRIRAAIDPALLFDAAREGLLRLQRGERSMAIYRRCATALSFCFLTVASIGLGMVAFLDMLSSTSIFLALTIAGALTPKLSPLFQRFFTTSLDVKGMSIGAIELVPPTLFMGLSFAAGGAEFAVRTKPARRIYQPPYRYGERVPVYVPVENNTRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L9</accession>
    <name>A9B8L9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="7" type="ordered locus">Haur_5055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07683">
        <property type="protein sequence ID" value="ABX07683"/>
        <property type="gene ID" value="Haur_5055"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5055"/>
    <dbReference type="HOGENOM" id="CLU_118482_5_3_0"/>
    <dbReference type="OMA" id="PYDLQIA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="3"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14764" checksum="893F47640AC6FC9F" modified="2008-01-15" version="1">MIYLLDTNTCIRYLNGRAPAIRTRMATVRLTDIVVCSMVKAELFAGALRSQTPGSSLAKQQQFLAPFRSLPFDDGAAQVYGRIRAFLTTHGQLIGPNDLCIAAIALQHNLILVTHNTHEFQRVPGLLLDDWEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8R8</accession>
    <name>A9B8R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07732">
        <property type="protein sequence ID" value="ABX07732"/>
        <property type="gene ID" value="Haur_5104"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5104"/>
    <dbReference type="HOGENOM" id="CLU_868108_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5166-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="35087" checksum="4EC04FC06BEE5BDD" modified="2008-01-15" version="1">MRPDLPLQRFLGFDDPAKPDHYVTKTQLVARGLIPGDPVAVIVRPKQRKPIYLSDRHHAIPRQSSSAIPRSTTTHQPPIACAACGTMGDHDHRIILDSLRTDRAEPPAPVCAACFAACAAEERRMDVQALRAQAQAWLAACVIVALKTTGDDDPDILELGVIDHTGMVLMQQRVTPLWEPEPPAVALHGSTLAMGGDAPDLTEVVPALAAIVHGKTVLVAEQDDIDTLINGLDMRDHDPRILLDHATWCDLLEPYSDWFGNWDDRRRRYRWEPLVPTHDVIGDCLALRARLQEMAAWSLYGGCGIGAVALPASLTPLIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8U3</accession>
    <name>A9B8U3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07757">
        <property type="protein sequence ID" value="ABX07757"/>
        <property type="gene ID" value="Haur_5129"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5129"/>
    <dbReference type="HOGENOM" id="CLU_2154884_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5191-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12533" checksum="4B285B47A7A865E3" modified="2008-01-15" version="1">MLYPPHIIVTVSLYPSGQSVYPLSLQGTDIQFRYGYPPHDWFCCFYGESDQEGYLMPGETTIGGIEMFSPDAHFDQFWVGMPFQLAYGQSVIADGIILDVVDLRMLAPTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B950</accession>
    <name>A9B950_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5237"/>
    <dbReference type="EnsemblBacteria" id="ABX07864">
        <property type="protein sequence ID" value="ABX07864"/>
        <property type="gene ID" value="Haur_5237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5237"/>
    <dbReference type="HOGENOM" id="CLU_1439275_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5299-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="18645" checksum="4A8D39967333DD02" modified="2008-01-15" version="1">MKRLLGILVVVLVAALAGWAWIRTLPIANAAAPSVAESAMVDGGGYGIYGWDGGLQVVLIYEGAMAAQTCDIDPADGAADEVYRCTIPFANGTTTQWSIRSADGKTGRITVDGVTYALPREATVLRISADGVGQRVTAYQRMLPPLTMGDASRTLEQWMARDSEFAPFAALFRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B955</accession>
    <name>A9B955_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5242"/>
    <dbReference type="EnsemblBacteria" id="ABX07869">
        <property type="protein sequence ID" value="ABX07869"/>
        <property type="gene ID" value="Haur_5242"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5242"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013584_15_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5304-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="68455" checksum="475B763B19E64DC3" modified="2008-01-15" version="1">MNTTPLDERGTALTAWINQTQEVLAHRSLNQQPFHRVFNLMRTRRLATVALNRVLSNTGARTAGIDGMTKKHIATDTEQQALVQEIWHDLTTHQYRPAPVRRVYIPKANGQQRPLGIPTIKDRVVQEMVRLILDPIYESTFYRHSYGFRPYRATHHAVVRLRDLIGRRGYQMALEGDIRACFDRIHHTTLIRILRRTIKDERLITVIHQMLKAGVMDDGQWRVTEDGTPQGGIVSPLLANIYLNELDQWVANRWDTYTPLERYYHRKAGTGYPCQITRYADDFVVLLHGTHAEATTLKTALATFLADHLHLELSAEKTLITPVEQGFDFLGFHIRKYQDSTRITPSRKAIATFKREAADRIGKGFRDSDEAGIVMLNHYLTGWGHYYRRVSSSTTFRSLDHYIWWRVMRTTFRLRRGRGVRHFGTHCRSHRKRYRDGLNRKHAHRRGGHYGVWANTAQTRAYIVTSLAFLPIEYVALHPQLHPYRKADRAKLDQRKRLALLLARNSHPERPANPAYGKAWEQIRQEVLQMSNYTCQHCGTRVHRSTAEIDHRIPLKRFTRRQTAHKLENLQCLCRACHLRKHGKEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU99</accession>
    <name>A9AU99_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase, sigma 70 subunit, RpoD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0367"/>
    <dbReference type="EnsemblBacteria" id="ABX03018">
        <property type="protein sequence ID" value="ABX03018"/>
        <property type="gene ID" value="Haur_0367"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0367"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_4_0"/>
    <dbReference type="OMA" id="RRVQREF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-370-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="391" mass="44684" checksum="9744D8E292A0797F" modified="2008-01-15" version="1">MFTRRNVVDCIENPAGSIDSFRAPPAAKAIVGVAQRAWTMTKYETMNVAKNQPELEDAPEGWELEPGFNDEDVELAIVNLRRKKTLYSEAVEDSVQMYLREIGEVELLTAEEEITLAKQIETGRKAEHQLQTEQYATWDERTALERRVDFGNEGRRKLTQANLRLVVSVAKKYIGNHMSFMDLIQEGNIGLMRAVEKFDYRKGNRFSTYATWWIRQAVTRAIAEQSRTIRLPVHLSESIAQMRRVAYQLEQALQREATPDELADALGVSLRKVKRMLNASVQPVSLEQPIGKEGQGRVGEFLADDTDEAPLEQATRMMLQDELADALSQLPDRERQILLLRYGLADGKRRTLEEVGAEFGITRERTRQIEAEAMRHLRQPNVGQHLRAYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ8</accession>
    <name>A9AUJ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1882"/>
    <dbReference type="EnsemblBacteria" id="ABX04525">
        <property type="protein sequence ID" value="ABX04525"/>
        <property type="gene ID" value="Haur_1882"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1882"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_10_0"/>
    <dbReference type="OMA" id="NRQHWNQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1911-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1020"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2084"/>
            <end position="2160"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="3133"/>
            <end position="3209"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="4196"/>
            <end position="4272"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="5246"/>
            <end position="5321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1055"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2119"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3168"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="4231"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="5281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="5596" mass="613095" checksum="CB6E617A5F850CB7" modified="2008-01-15" version="1">[encoded data, 5596 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP0</accession>
    <name>A9AUP0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1924"/>
    <dbReference type="EnsemblBacteria" id="ABX04567">
        <property type="protein sequence ID" value="ABX04567"/>
        <property type="gene ID" value="Haur_1924"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1924"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099718_0_0_0"/>
    <dbReference type="OMA" id="SEFRAWY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1953-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="214" mass="23410" checksum="F6DCA02ADF03E46B" modified="2008-01-15" version="1">MFNPQAGYPFRSDNKPRNELFEFAKAWLGTTLAFALVYRNIMPLRDAVIIMGIAAGLGIVIHELAHRVVARRFGSEAHFFANDAMLVISVLLALTGFIFAAPGAVHHRGYLTKKQLGLVAAAGPASNMVIALLSLLLIPIANTLNIQFLFKISVYSYVVNSLLGIFNMIPYGPLDGAKIMDWDMRAFIAMASVGGLLFVVQYLPIATNLFVFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ5</accession>
    <name>A9AUQ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1939"/>
    <dbReference type="EnsemblBacteria" id="ABX04582">
        <property type="protein sequence ID" value="ABX04582"/>
        <property type="gene ID" value="Haur_1939"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1939"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1968-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="125"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="21838" checksum="2A8E649990EAC10D" modified="2008-01-15" version="1">MDLITRVRDVFTAPHPLVDPASFAQFYQQTHAVVFRYVYMLHGQPKSDVEDFTAEAFARAWKQRQRFSGDDQAALGWIITIARRIVIDQQRRATSAMGRLWAQLDRSPPTPEQQAIQRERQHLALELLAHVSLTQRDHLIMRYFLGWRVQTIAQHLGCSENAVSVSIHRALRILQTQYATLAEELFNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR9</accession>
    <name>A9AUR9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04596">
        <property type="protein sequence ID" value="ABX04596"/>
        <property type="gene ID" value="Haur_1953"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1953"/>
    <dbReference type="eggNOG" id="COG3609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1813559_0_0_0"/>
    <dbReference type="OMA" id="FYANRSD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1982-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041088">
        <property type="entry name" value="RHH_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17723">
        <property type="entry name" value="RHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14137" checksum="EE585845DBA12C31" modified="2008-01-15" version="1">MADIEKVSMNLSVVDLGQIDLLVDQGFYSSRTDFFRAAIRTRLAGHDEAIKQAVVRTSSVIGVISFDREHLERIQRNNEQVRVVVVGLLILSNDISPELAQATIKSLKVYGSLRASAAVKEALAERIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS3</accession>
    <name>A9AUS3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1957"/>
    <dbReference type="EnsemblBacteria" id="ABX04600">
        <property type="protein sequence ID" value="ABX04600"/>
        <property type="gene ID" value="Haur_1957"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1957"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009866_1_0_0"/>
    <dbReference type="OMA" id="YCRYIAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1986-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="109"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="485"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="968" mass="107358" checksum="F05DB6B243DA4A95" modified="2008-01-15" version="1">MAQFRVGSIVRCRNREWVVQPSTHPDILQLRPLGGIDGESCGIYLPIEGDTVTTAQFPPPDPAMAGDFVAGQLLRNAARLSLRNGAGPFRSLGRLGARPRPYQLVPLLMALRLDPVRLLIADDVGVGKTVEAALIVRELLDRGEIKRFTVLCPPHLCDQWSRELEQKFGIEATVVRSSTAAALDRTLPNADISVFEYYPFTVASIDYIKHDRHRANFLRACPELVIVDEVHTAARPSGPGSGQQQRYDLIRAVADDQERHLLLLSATPHSGIEDAFVSLLGLLRPEFETYSMTNLSSKQRDLLAQHFVQRRRGDVVRWLDEETPFPKREHMLRDATGNRDITYRLAQSSAYRSLFNEVFEFARELVHESLREANAPRVAARTRVRYWAALALLRCVMSSPAAAEKALMTRARKDPTTQADDLSLTFDDELFSSAIHDRSTPAADDDVEPTHVIEEGSTASEAARLQKFAEKARQLRGANDPKLQSIVPIVARLLKDDFQPIIYCRYIATAKYVAEELTRALKPGNDTRILAVTGDHSEEERESLIAELSASPRRLLVATDCLSEGINLQEAFNAVIHYDLPWNPNRLEQREGRVDRYGQPAPVVRMALVRGEDNPIDEAVMRVLLRKAVTIHRTLGISVPLPVSNETVVDALIATLFKPPATQLTMFEAIDPATFAAAEQTLAEVELQWAQAEHQAEQSRTRFAQHRIQPQEVARELEESDAVLGDADTVRSFVRASCERIGAPLVALGAHAPDHWRVPIIQLPLPVRERVEPLLRNKATELIITFTGIAAEGVLLVGRNHPLTMALADYALETALTPEDGLPVPAARSGVLRTKAVERRTFLALLRVRMLIATKRNEPLLAEELVVAGFVREPGGFRSLEPAAALDLLTNALPDANIAHADREHQLHSALDLLPQLAADLTSLAHTRAERLAESHSRVRTATRMAGKVSVEPHLPPDVLGLYVLLPV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUT1</accession>
    <name>TIG_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trigger factor</fullName>
            <shortName evidence="1">TF</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tig</name>
        <name type="ordered locus">Haur_3885</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AUT1"/>
    <dbReference type="SMR" id="A9AUT1"/>
    <dbReference type="STRING" id="316274.Haur_3885"/>
    <dbReference type="EnsemblBacteria" id="ABX06519">
        <property type="protein sequence ID" value="ABX06519"/>
        <property type="gene ID" value="Haur_3885"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3885"/>
    <dbReference type="eggNOG" id="COG0544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033058_3_1_0"/>
    <dbReference type="OMA" id="KGIKTQF"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0697">Rotamase</keyword>
    <feature type="chain" id="PRO_1000115543" description="Trigger factor">
        <location>
            <begin position="1"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="1">
        <location>
            <begin position="161"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="481" mass="53732" checksum="04E679F4675D0AEC" modified="2008-01-15" version="1">MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGKAAILEEATDEIINVAFRAALEQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKAITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAEGDQLTATVQTLVDGVPLHKLDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLIMEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAWEELPGLEEFEGDLDAYKADLMERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAERAHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPRGEESLKSSLVVRKIVEAEGLSVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV01</accession>
    <name>A9AV01_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3957"/>
    <dbReference type="EnsemblBacteria" id="ABX06589">
        <property type="protein sequence ID" value="ABX06589"/>
        <property type="gene ID" value="Haur_3957"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3957"/>
    <dbReference type="eggNOG" id="COG3161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107938_0_0_0"/>
    <dbReference type="OMA" id="VIIITEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3999-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002800">
        <property type="entry name" value="Rv2949c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01947">
        <property type="entry name" value="DUF98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20838" checksum="A9B0AD30019290D7" modified="2008-01-15" version="1">MENGLQQSIDMAVLNPLERILLITDGTVTEILQAYYREPINLIKLSEKISTNRDIDLLDVRAGEEVLERQILLQGRDSGRTYIYAESLIAIEKFDDELRASMRDTLLNSNLPLGRLWLDHRLETFKEMVSQRQEKAHNLCSIFDISNDHHVVLRTYRVFSRKKKIMLITEMFPLNYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV12</accession>
    <name>A9AV12_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3968</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.157" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3968"/>
    <dbReference type="EnsemblBacteria" id="ABX06600">
        <property type="protein sequence ID" value="ABX06600"/>
        <property type="gene ID" value="Haur_3968"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3968"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_0"/>
    <dbReference type="OMA" id="FYDYSES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4010-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="3">
        <location>
            <begin position="186"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="30997" checksum="5DE89E4482604D78" modified="2008-01-15" version="1">MAIKKVGVIGAGVMGIGVGQSLAQGGYEVVLIDINDQILEHAEREIRSNLRLFKMLNKGVELDIAATLGRITFATDYEHLSDADFVVENVVENWEIKKAVHLKLDAICPAHTVVAVNTSAISITRVGSLTKRPSQIVGMHFMNPVPMKPTVEVIRGYHTSDATIATAKELLAGMGKKGVVVQDMPGFVSNRVLMLTVNEAVFLVQDQVASAEEVDTIFKECFGHKMGPLETADLIGLDTILYSIEVLYESYNDSKYRPCPLLKKMVDAGLHGRKNGKGFYTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV18</accession>
    <name>A9AV18_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oleoyl-(Acyl-carrier-protein) hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3974"/>
    <dbReference type="EnsemblBacteria" id="ABX06606">
        <property type="protein sequence ID" value="ABX06606"/>
        <property type="gene ID" value="Haur_3974"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3974"/>
    <dbReference type="eggNOG" id="COG3208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070456_1_1_0"/>
    <dbReference type="OMA" id="ALCRLIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4016-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016295">
        <property type="term" value="F:myristoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004320">
        <property type="term" value="F:oleoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016296">
        <property type="term" value="F:palmitoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="31555" checksum="B0E630FCC11B139E" modified="2008-01-15" version="1">MRAELSWHTTESLLYSEESSRRNQKHPMTTIDQTTTKWLTFPRPNPQAKIRLFCFSYAGGGASTFRPWMQHLAPSIELCAVQLPGRENRLREAPLTRVDPIVDTLKQMLPAYFDKPFALFGHSLGAILAFELARALRNHPEARLAHVFVSARIAPQAIDPEPPIYQLPEAQFLAKLRQLNGTPTMVFENEELLEMLMPILRADFALNETYAYRPEPPLDVPLTVFGGTEDPKVSEAELGEWSAQAGGRFALKMFPGDHFFVSSAQQAIVSLINGELQTVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV30</accession>
    <name>A9AV30_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03108">
        <property type="protein sequence ID" value="ABX03108"/>
        <property type="gene ID" value="Haur_0457"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0457"/>
    <dbReference type="HOGENOM" id="CLU_1223354_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-463-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732167" evidence="1">
        <location>
            <begin position="26"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="226" mass="25490" checksum="5FD26492952CB432" modified="2008-01-15" version="1">MFKKLSLIASVVLMLIVTQFTPVEAQEQSRQMVLVAVDVSAMCSESIDSAKNHPCEKGSSISVYSMPLEDAQKQGYGEYVFITGDTTLDRLASKQLADTLHLQLTNDKQKAPANTQACGSYYKSISRSFTMGGGVYKLDTSVQYKVNPTCQVSEETYRVKTSKTHYELLTWSINFPNVNVYNSIQSQPGLTWTSYAYNVWMNSGFQLSAETYFPGETHWEYYTLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB9</accession>
    <name>A9AVB9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1967"/>
    <dbReference type="EnsemblBacteria" id="ABX04610">
        <property type="protein sequence ID" value="ABX04610"/>
        <property type="gene ID" value="Haur_1967"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1967"/>
    <dbReference type="eggNOG" id="COG1372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_228629_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1996-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HintN" evidence="2">
        <location>
            <begin position="2256"/>
            <end position="2349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2205"/>
            <end position="2254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2486" mass="273653" checksum="0FCF965375CC03D2" modified="2008-01-15" version="1">MLPIRRRRWIPLALLLIVIVSLLPLQSTSAIPMLPQSDALTKRVPEILDEPPVNNRPSPAQSAVTPKEEAQNIAPVAESQHSFSGIDLTFTGDTISQVPVAATNAAVYVAQATVNDLYIVNGQPHYNSDNLSYYEDTGIFMNLPRDSFTVNVEVAVGNIGFIYIQSVNNPQIYQKAAFTTPQGNPHDMHFTIGPSIPRNQPIHIYVGCFNPQPGGYNNCRYTNFQFYLDSDVLTRIPDPAYDHPKKLLPSYINQVNTGKYLPADGAGNPFFMYGYLPPVQGIDEKFLYQTKAFNFPALQPNDTITINFRYSAFSWPGTTPANSFGSHINLFFSDANSSTYDVFGWDTLSRDLTNPINIPIPGFSTYSYIPWRSGSITLNQNIYSQISNKTIRINLAPQSADSQYYPYLAGIDSIQFYRNGKLMNFSSIEDRIPADQNGGSCAPCTAAGESTMIVGDPVNTLSGAYIEHGVDQQIPTGGTALSLQRTYVSTLANSSLYPQSSLGLGWRFNYAESLTLPVEITGVTTVGAESNTVIYEAADGNRYRFKRHGNDFVAARGIRLTLTKNATSYTLQAADQSAKTFDLQGRLLQLRDVYGRTQTITLGTSGIQTGLPVEVRDDLSQRKLRLEYTTTSGVVRLYRLLNDLNQATVYEYTQGRLEWVTSPQSILSRYTYDPTSLLMSSVTRNATSKSPLPTADLVMSYTNGRVTQQTAPADNTVWAYTYTGTGANQAQTTTMTVSRGGIVLDVQRSHYRADGTFAWQERNDALLEYVANDRMLAPTAGVKADKSIALHHNNPKGQPVEVYAGAIEGAILGTTQRTFAISYTPTGYPAIVTNTNGLETYTTYNSANQPLTTKAGTGTLVPTQTWTYDAATKQPQTITSPDGIVTRYTYTAAGQVASTEVGYGTSSVQKTTYQYDSLGRQTHMTLGDGLPNATTTVTEYRPDNQIAKITRNYVAGNTTDPRKNVVTEYGYNAKGQLIWTKTPDGRYRGVTSYDALGRVRWVADNTVNPSTGAIAIADTSSTSLPPSFSPQRPDANIVTMYGYDWHGRTTLITQTGIVTGTFNVATLQWQSSTSRVTRIEYDQLSRPVTTTYNYRPDIYAGQFNTNHPDVNVPTYTYYDGAGKVTWTRDGLRRWNHFEYDQLGRPVTTTLNYENGDPLTVDPVNATWASTNDTDIISITHYDQGGQIDHTIRNFVDGVRDTTIPDSSIPWQITDVVTDVVTRYHYDQAGRMDQTISNYVAGATDPEFNRVANTIYDQATGRTLGVTDAWNQYTVYEYDQLGRSVSSVTNCRTSSGVPTYNRNTCASTTSQRNLPSPLSVYDQLGRLSQTLSVDAIGGLGFNGPPTQYSYDGLGQLVETIVNSQPGQAASATVNVKSTTTYLDAAGSRWNETDPTGKITQYETDGFGQVNKVIDPAGLITLSGPRWTKTPDGQVRVAMIDGLGRTIKTVSNYQDGVYVPATDTTTHDIITLTRYDVGGRQVAVTNSLNIRTRYDYDLRDNLIRIIENDLGTCTASDTNDCQVTTEYRYDRVGNLIKTIDARGYSTTKSYDSLGRVRRTTDGLNRHTLLTYNQDDTVATIAPATGNPISYSYDEVGHQIQATGWDSTAVQQWTYDLAGRLSSVYDASAQDAAAGRTGTISYKYDVLNRISSVAQSLEGDPQGNWTLTYGYDAAGRTTAIGGTSYSYDTAGRLSSVIRGGSPLAQYAYQGSTGRVASITRLEAGNNRLIESLGYDTRGRVTSRSITGATTAAAMPTPTAPQLAQFTYAYDRADQPTSFTETQLNSAGTATTNETHSYTYDKLNRLISENASGTTTTFRFDAAGNRIKVNSQNSSYNAANERVGFAYDVYGNVTGDGQNVFSYDGFNRLKSVIKGANVYSYRYHEETLTSRFVNGTRTQAFNYDRVGTSLSSILRIHTIQPTDTLYTTYITGLGGDIIQSEATFNGAPQTNGKLFLISDNQSTVRMLVNASNGARTKQDSDAWGNFVPAAGQTLAPSSIRYTGEYTDRDTGLVFLRARWYNPASGTLLSKDPFAGFANQPQSQHPYIYAGNNPTTNSDPTGRTCEGCQPAGVTRDQWHQYVDLYDVTYSGFVGALINHPFDRMGDATVFDNYAHATRSSLDFIYYLKNFLWGCSIQQYGALENLWSNAETWSEHFYHDRLPSVPLHRYDSIEDAMDALGDEAYLNYFIETNLADGNHLDPIDSISPGLADVPVVPSTPRQNNPSTDVDDPAPAKSPKPSNDPDVDVDNPAPSISPKVGESCSFDATTLVATDEGLVPIATIQVGDLVLAYDEATGTTDYYTVTASFVHSDPVLVDVAIDNEWINTTPEHPFFTADGWTDAENLELSDWVASADGEWGKITALRLRGDQRFMYNLTVAEAHTFFVGDGRWLVHNVCIDGVEYPVDKPTNQTKNDSIWYDTQAQARQMARQKMGHNPVEIEPNKLRRRDGTWQYRAKPGDLAGDNQGPHIHLEKLDPKTGDVLINLHLRWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC2</accession>
    <name>A9AVC2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1970"/>
    <dbReference type="EnsemblBacteria" id="ABX04613">
        <property type="protein sequence ID" value="ABX04613"/>
        <property type="gene ID" value="Haur_1970"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1970"/>
    <dbReference type="eggNOG" id="COG4935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006954_2_0_0"/>
    <dbReference type="OMA" id="TGEYTQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1999-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="734" mass="77365" checksum="7C4FF412A5EA0D02" modified="2008-01-15" version="1">MRLGRSWMIIVAVMIIALLSVITATAMVSPSVSSSDGLWQNVAEQDIQQKGSREIIPVVYRTVALDLNLLQQHLRQVPQEAQTKVQKSGFMLDLPLPDGQFGKFRVVESPIMAPELAAKFPEIRTFLAQSVDQPATSARLDITPRGFHGMILSESGRIFIDPYSRNDTANYIVYDARNFVADPSKLAERTGNDYEPNPLGNPSSIIPERYSIGETLRTYRLAMAATGEYTAFHGGTVNGAMAAIVTSMNRVNGIYERDLSVRMQLIANNDLIVYTNASSDPYTNNSGGTMLGQNQTNLTNVIGGANYDIGHVFSTGGGGVATLQSVCSSGSKARGVTGSGSPVGDAFDVDYVAHEIGHQFGGLHTFNGSTGSCSGGNRSSSAAYEPGSGTTIMAYAGICGSENLQPNSDFDFHVKSLEEISAFITTGGGATCGTTQATGNTPPVANAGSDYTIPANTPFELTASANDAEDNSLTYDWEQYDLGAASPPNTDNGNRPIFRSFNSTASNVRTLPKLSDILNNTTTIGESLPTTNRNLTFRLTVRDNHAGAGGYGLDTAVLTVNNTAGPFLVTAPNTAIAWTGGANESVTWNVANTTAAPISCANVDILLSKDGGTSFEALVSNTPNDGDETVVAPNVNAAAARIKVRCANNIFFDISNANFAINGVNITPTPVTPTLTPTNTPTRTPTLTPTQTSTPTQTATATPTASPTVSVTPTASVTPTPENYSVYLPVAIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVJ4</accession>
    <name>A9AVJ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2042"/>
    <dbReference type="EnsemblBacteria" id="ABX04685">
        <property type="protein sequence ID" value="ABX04685"/>
        <property type="gene ID" value="Haur_2042"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2042"/>
    <dbReference type="HOGENOM" id="CLU_896510_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2071-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="35158" checksum="419EB4C2E30288ED" modified="2008-01-15" version="1">MAEFITEYIKKIQIGESLVEFNQKNNALKENINILNEESKLADSIQKIDGFDSSGDEPSDKITQHDNNTKNEMDSTALLYPDEIDNETKTTSLYKKVFATAITSPSAALMFLSSRIESKIRKDIEPFIDTEQSKKPRSIHEMVHLGVNVGIFPPRLEETIRDFWYIRTKIIHGESTQYKSADIMSLIHSGFEIMNILSKSLHTETFTRTYRHILEYLATEGPISKKDIANRIGQSAYANQIKLTYEPWNLIIHTHENHIAINDRGKAFLAGTLPIPESIIRLYTGDWIAVPNTQLITVADVDNDSQLGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK3</accession>
    <name>A9AVK3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2053"/>
    <dbReference type="EnsemblBacteria" id="ABX04694">
        <property type="protein sequence ID" value="ABX04694"/>
        <property type="gene ID" value="Haur_2053"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2053"/>
    <dbReference type="HOGENOM" id="CLU_1052795_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2081-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="29083" checksum="1E3A5A2C1BFAF94E" modified="2008-01-15" version="1">MIVGSFQPSAAQTGFASTINRTLIPYNAPTGTHREFATSVNVGHGPNREKARFLIQMVDLPHVAGPYARICGIVDHHCPHQNVCLTLHFVWYIVHFSLLDEDLVMSFHEKSAWASLLAVGLVFTPYFVVVLRYPLAFGILVVAVIALVLILMGFHSINAISSTLIRKRGTTPPIDELDQLIELRAAKRAGFVLAFAVLTWCLLAMVFVPVWGVAAGGPSNNLAEFRLPITQVLTAIHWLFASFVLANCVYYASIVVSYRKLTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW0</accession>
    <name>A9AVW0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0550"/>
    <dbReference type="EnsemblBacteria" id="ABX03198">
        <property type="protein sequence ID" value="ABX03198"/>
        <property type="gene ID" value="Haur_0550"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0550"/>
    <dbReference type="HOGENOM" id="CLU_2382178_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-559-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="94" mass="10585" checksum="A5C4A3D4A6D9A5F5" modified="2008-01-15" version="1">MYAVYGIPPHELYEETVLELLPSYLRRMHNEREQQAMLIATKVGTMLFGDDTKGKGKGTSKRKKANQPASTRSEVNYVSASQLIANMKARSVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW24</accession>
    <name>A9AW24_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
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        <property type="taxonomic scope" value="Bacteria"/>
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    </dbReference>
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        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
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        <property type="entry name" value="Apc4_WD40_dom"/>
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        <property type="entry name" value="WD40_repeat_CS"/>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
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            <begin position="5"/>
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    </feature>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="557" mass="64077" checksum="3A8A6E371FF08A20" modified="2008-01-15" version="1">MLRRTFWVIIVGILLVLLNFKINGIELLPNWLGLLLIFGALLRLQQAYVYFKRATWLSFFALGQSIPWFESPTTLPDDPWYQYGFVLSYFFYGIYLWMIGEICYALVRYQRLAEPERSNRPLVLSYLALMSHLIFLLLLWIWPALGVSLLTMVALGIGFIAYAVVFFQWQRYTKRLNSIDFGIQHTPRFAAWLKVTIVILLIVPLLGLSSTWINPTNPLVANEPTATAIYRQKFSRSYVLPKNPIAYSPDGSMLALIDKEIVELPEELQNNYDFTITKLYLLDTADYSKQRVITLGDNVFVTNMTWNHTGSQIFVSLGRDSSTINYIIDPIKADIKFSKEGKYIGFLNSARWSADDRIITLLANSVWEFNAITGEMQIISRPIYNPSLKADLSPDSQYIVYRDELQDSLDIYRSPDWIAYTNLQKNIEYVYNLSWSNDQKLIAVAKSNDEIQVWDAASGQSIHSLLITYQDDRWWNAKTYATFAQSVTFSLDSTLIAGGSHDGNMMLWQVDDGRRLLRFDQQQSGIIAIAIKPHNQHMASIDEDGNLLIWDIMKVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW52</accession>
    <name>A9AW52_HERA2</name>
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    <reference evidence="2" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX03290">
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0642"/>
    <dbReference type="HOGENOM" id="CLU_2232833_0_0_0"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="105" mass="11592" checksum="74B87A713C39C7ED" modified="2008-01-15" version="1">MTPTHVNHDRCQRLARASAIVQLATIIQEEEGLDDNTAYILAEQELDAIAATEAAWSDQQPVAMLRILPTAWGVVLVRNGSRLVVHRTDIPAVLESLTRWAASSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW83</accession>
    <name>A9AW83_HERA2</name>
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        <recommendedName>
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    <organism evidence="2 3">
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            <taxon>Bacteria</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04733.1"/>
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    </dbReference>
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        <property type="gene ID" value="Haur_2093"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2093"/>
    <dbReference type="HOGENOM" id="CLU_163276_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2121-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="InterPro" id="IPR032693">
        <property type="entry name" value="YtkA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13115">
        <property type="entry name" value="YtkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10581" checksum="8D0A35A695E0BC8F" modified="2008-01-15" version="1">MLQAHLEQTPNTLGQHAIIITIQDNGAPLTTPAVQLETTMSHAGMASQMIPMESLGDGRYTANLNIDMLGEWVFIVHVPDPTGATSARQKTLPAFNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG6</accession>
    <name>A9AWG6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4093"/>
    <dbReference type="EnsemblBacteria" id="ABX06725">
        <property type="protein sequence ID" value="ABX06725"/>
        <property type="gene ID" value="Haur_4093"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4093"/>
    <dbReference type="eggNOG" id="ENOG502ZQA3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1719078_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18268" checksum="2FA0825366F40113" modified="2008-01-15" version="1">MYFTQNDPQILFPSWVAGLLVIWIAVLVGAIFWLRSLPPKNPARLAFRKRTSNGLLIIAGIGIVQFLARWLKIDVVEWRLWGYVLFVALIGFGLYSWQYARSTLPALVSQTGKVKSNYAKSRAAAAGSNAKASADGVASEPAAPREPKPIATTGRREARRSKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWJ5</accession>
    <name>A9AWJ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_4122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4122"/>
    <dbReference type="EnsemblBacteria" id="ABX06754">
        <property type="protein sequence ID" value="ABX06754"/>
        <property type="gene ID" value="Haur_4122"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4122"/>
    <dbReference type="HOGENOM" id="CLU_1813151_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4168-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="16437" checksum="A23CE62B435DC8B5" modified="2008-01-15" version="1">MISSAMLPIRSFWIHSLEVLMSYQMPNNPQGNARIRKIMLIIFSCLCVLSIPIIFFAYQTSKALDDFYFGTRSNAVNSSWQILSIGSLGSLALAAFFWSRSIKKQWQESKRKYNLILFLQLVSLSCMTLSIWNLLYLFIYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP6</accession>
    <name>A9AWP6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0649"/>
    <dbReference type="EnsemblBacteria" id="ABX03297">
        <property type="protein sequence ID" value="ABX03297"/>
        <property type="gene ID" value="Haur_0649"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0649"/>
    <dbReference type="HOGENOM" id="CLU_2046419_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-660-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="13725" checksum="C526E91828334BA3" modified="2008-01-15" version="1">MTEGDLLKVYGPSLFLVGWFLYREVWPLLKERLRPDLVAQRRKAESQAEAKVLTAFIDNTVAMTGLKHTLEVVSDEMGRLREGQEVHTQLLAEMFGFFRQPRPSPNPSTRPRPSKKGETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWQ4</accession>
    <name>A9AWQ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0657"/>
    <dbReference type="EnsemblBacteria" id="ABX03305">
        <property type="protein sequence ID" value="ABX03305"/>
        <property type="gene ID" value="Haur_0657"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0657"/>
    <dbReference type="eggNOG" id="ENOG502Z96S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085672_0_0_0"/>
    <dbReference type="OMA" id="EAYRPEK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-668-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024659">
        <property type="entry name" value="Phage_coat_Gp5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11651">
        <property type="entry name" value="P22_CoatProtein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="30559" checksum="1FF7797B858FC6D0" modified="2008-01-15" version="1">MALTNFIPVVWSARILSNLHRAHVYGQAGVVNREYEGEIRDAGDTVKINSIGPVTIGNYTKNTNIGDPETLTDAQMTLLINQAKYFNFQVDDIDRAQQKPSVMDEAMKEASYGLRDVSDGFIASLYTGVAAGNVIGNDTTPVTPTSANAYDYLVDLGTLLDEANVPSEGRWTIVPPWFHGLLLKDDRFVGVGSASSDQVLRNGQIGSAAGFSVLKSNSVPNVAGAKYKIMAGHPMAISFAEQIVKVEGYRPEKRFADAVKGLHVYGAKVVRPTAFAVMTANRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY4</accession>
    <name>A9AWY4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0737"/>
    <dbReference type="EnsemblBacteria" id="ABX03385">
        <property type="protein sequence ID" value="ABX03385"/>
        <property type="gene ID" value="Haur_0737"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0737"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_1_3_0"/>
    <dbReference type="OMA" id="WYNTPWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-749-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="142"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="37572" checksum="901CF622CF3E5B32" modified="2008-01-15" version="1">MKTIRLGVLGAGLAVKHLHLPALKALPNCFEIVSICDHNWANAEALAGLLDLHPTITDSWVDFFADSQIEAVLISLPIQRNAEAIQAAVAAGKHVICEKPLAANLPQAEALVAACQHAPVKILIAENFHYRDDLKQARAWMDAGAIGDLVLIELRATFWSDPDQGFGATPWRHDHQYRGAVLADAGVHQAALLRELGGPIESAHAFIKDVHPVLRGPDTMVLNLRFASGVLGSLCFSGAVKTENPCFDWTVVHGTHGSITIRGDQTTLYRADGTIEHYQAQDLRGYISEFRNFYAAIVENEPIVASLATALADWRLIMRAIDAAESNSVQQIDPIVPLASLNDLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXA9</accession>
    <name>A9AXA9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06829">
        <property type="protein sequence ID" value="ABX06829"/>
        <property type="gene ID" value="Haur_4197"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4197"/>
    <dbReference type="HOGENOM" id="CLU_1784222_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4244-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="16907" checksum="418E06F65932F95C" modified="2008-01-15" version="1">MTDIDARNRITRLEKEVEALRQELSVLRVELRQFIKPRTTTKHQPTFERNLAPEREPEALADVAQQLSEQVSSEEIGAYLKRRRVTASDIQLTEQDLQRNQPRNRRAHHGYPSKPYNLEAFYGSTQTFIVLFCLIALLMVLLTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXF6</accession>
    <name>A9AXF6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4244"/>
    <dbReference type="EnsemblBacteria" id="ABX06876">
        <property type="protein sequence ID" value="ABX06876"/>
        <property type="gene ID" value="Haur_4244"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4244"/>
    <dbReference type="HOGENOM" id="CLU_525593_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4291-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="518" mass="58392" checksum="91D162880AB471C6" modified="2008-01-15" version="1">MNHDLAAVLDYLDQRFGSSDRQAFEERLAQEPQLRELLEKTKSMQRNLRSIFGQSERLVAPSRSRRRVAKFSRFKYTINALMLVVLLLGGVYLKKQFDIAPQISNEPTYLALANEETSLPQQQMLLVKGIDHEQNHFVRAMQDDQVMWQANNVDALIIADNGDRIELSKTQSHYVLSRKSSDDNPTWQQSLPLQPDTSTVVGLYQSANQQELYLTAHTKKPTNQTADLAQSVTIIPQQQVDTTVYPSASYPLGVSAEQSNSITDVLDDVAGSVDPMSSPINPPNAQAGQQAQQEAGQIPTNVVTNQQLLIIDSTNGTIKHPNQQCDCRYLASNQTLYPYDQAFPFTDYFNYAISANNPNLLSLITSDQDVITYDLKNQTILKTSKLASNQQLNDHLYASQLQFDLFGQTTSINPDLARITDVQFSGNQQTIIIRDSTEDKTTFYAFDRLSGKQLWQRSILASTVSFTPNWDGSEVYAVHTSKPTETGFSTLYTVQATKTTFIDYPQQQFEEIIMVYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL3</accession>
    <name>A9AXL3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MLTR_LBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0779"/>
    <dbReference type="EnsemblBacteria" id="ABX03427">
        <property type="protein sequence ID" value="ABX03427"/>
        <property type="gene ID" value="Haur_0779"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0779"/>
    <dbReference type="eggNOG" id="ENOG5033674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082999_0_0_0"/>
    <dbReference type="OMA" id="IINIAEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-791-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MLTR_LBD" evidence="1">
        <location>
            <begin position="125"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="35864" checksum="2E2B782460892E4B" modified="2008-01-15" version="1">MALGQQLVHPDCLAFVAVVEELLARRQQGLVPQNRWQLADDPWGPRAWNRTELEDMVYSSYKQMRKGRITRPPRREVVMDIADYLNCTIEERNRLLIAADGSPIMPYLTGAALTPILEITIEIVQQLSMPAFVINRDWQMHYFNEHLLNLFGVTPEMLAAIDPTQLNVLGLLCNPDLPLYPQLIQNRASWQFMVRKTIYGFKQANVLCQYEPWYQQLVAELLQLPEFASQWPTVSLDKPLVTPNMGLESPTIVLEALIPHTKPMPKRAWLRPLLMSAGYFQFDFPQIVAFLPANAESQAIYAEIGVPLGINHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN4</accession>
    <name>A9AXN4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0800"/>
    <dbReference type="EnsemblBacteria" id="ABX03448">
        <property type="protein sequence ID" value="ABX03448"/>
        <property type="gene ID" value="Haur_0800"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0800"/>
    <dbReference type="HOGENOM" id="CLU_632786_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-813-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="2">
        <location>
            <begin position="359"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="433" mass="48285" checksum="8DF9687CE68ADFC7" modified="2008-01-15" version="1">MINRQSAKLIVLLSACIAYSSLISVVLNSLDSAGEQPSAVWRWPIFVFGTITMVSLRMRLRQRGAIITAAAAIGIAMVGWLWIRSERSGQELVLSGFGVGFLMSRAINSDQWNHDWLQQLFWRGLGVLVAFVALGPVMTRGALEQPGLLQLFIIQALAFVAACLFAIMLDQSNQAELQTPPMLGWSSLFTLALVAIPLLLFGVADGQRSILGLIFGAFMDGLVLIAGGLAVALSWLVGWLIPSFKPNQRPPIEPSMPEAVDPSTLMPEETSQISSWLGDLLNIGVAIILIMMIAWLIYRVVHWLRDFETKPIAQGEVVIEQSIWSFDSLREQILERFRRKKPWKLDTNDPQVQKVRRIYTQFLELGEDHGQPRSKHQTAHEYGRGYAQQQPTNEPAIAELTAIYTQARYAEQLDAEAVARAEQALKTIQKQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY97</accession>
    <name>A9AY97_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4347"/>
    <dbReference type="EnsemblBacteria" id="ABX06979">
        <property type="protein sequence ID" value="ABX06979"/>
        <property type="gene ID" value="Haur_4347"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4347"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_416675_0_0_0"/>
    <dbReference type="OMA" id="RWLMFSA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4400-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="597"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="630" mass="69860" checksum="C139EF087564F4BD" modified="2008-01-15" version="1">MVVDTMTIFSQRRQWLTLVTLLIGLLIGLGFVSNRQWQVPLNLGLEEGINNDAPFVVGFNAGEQLPDRSARYRWSTLNAQLRFPHVPQRHYWLDLPQLTGNPASLIMGTSQFTSTAGRVLHVLLPADAAGKVAITVAQPVVSDDPRELGAAFSGGQLSSSGWAWPGLYPTLAWLFLLTTLGLSIIWLGGSSLEVGLAVGLTGLGIVAATWFAPLRASYAAPAVAQTTLYGLAALLLLGWALPPILQRLGLTISRDVLRWLILATVLVWSLKLGGRLLLEHMPGDIGFHRNRIHATNLGDLFRPSRHRGIDFPYPPVLYALLQPLTLTGISADWLLQLTAAACEALAIPVLFCLGLRTTGSSRGALVGAIMYGLVPAGFMTNAWSFDSHIFSQFVALLLATFMVWTWQHWHERRNWLWITLGLSTIALGHFGFYLNTGLMGGLLMLWLWWRGPRSQGWALFTSLVATQVIVWALYYSSFIGLFLQQGQSFAEGGMNAVNQREAVPRLQLLWDMIDLGFWRHYGLLPVLIAPFGWWLSRKHRGLQLVMGATFVVSLILAAFPIINGSTITTRWLMFSAWAIALATGIALDWLWQRTRWGRWPAILITSGCAIFGMIVWFAAMVYKIRPPEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH5</accession>
    <name>A9AYH5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0909"/>
    <dbReference type="EnsemblBacteria" id="ABX03557">
        <property type="protein sequence ID" value="ABX03557"/>
        <property type="gene ID" value="Haur_0909"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0909"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_347078_0_0_0"/>
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    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="420"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="490"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="760"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="780"/>
            <end position="799"/>
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    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="281"/>
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    </feature>
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        <location>
            <begin position="717"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX03557.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="813" mass="86374" checksum="20D1052AEBF57EA4" modified="2008-01-15" version="1">MGLGFTFNYAWRSLRLGGQRTLLAIICIGFGVMSLGSMQSLSTAINQIFIENRVSVGGDAMLDWPNGSIGPEQQAQLEQWKQAGVIGGYVVYSAIPPGLLKPAGGDHVIFGDIGYGIDPQSYPLLGELHVSQPANASMSELLSQPDALVATELLAIQHDLTIGQELVILVDQGATPKRLKLVGLVDQVPNKSAGSLFFSLATAHEIYPEANLNSVRVVWGQQGVQVGVLEQAGWSVATVSSEPSDAAGLFNMTLRGAGVLGLIVSGIGVANTMQVVLARRRNEIAILKTLGYRGPQLLLLFGFETALLGLIGSILGAVAAVLIGDQLTDLFARSSAYILPTVVDWQILGGAIGLGIATTLIFGMVAIVKANAVRPGSLLRSGPIEVNPTTRRAMVGLYTALGAMFAVVASISMGSFVAGMLLFAGAVLGLALLNWLFQAILLLVAKTPLPGYWLRLASRNMQRNGQRAAFAIIALAIGVFTIGFSAAALLTVQKELDARADPNTNLNRAMWVITAPSEASKVAQTLQQLQQPTLEPIQLLEVETSLPELEGVKFETSARSATQIGDIQLTEGQWQAAADQVMFSTWFFSEIPLGTELELIGSNGRLNVRLVGRYENQASQASSAIVIGPDAVSQLVAQPVTLIYVLNLPINQLSTATNTFNQAIPQAFVYNEVEMYNTTQMIYRSLGLFVVAVAGLAFVAGMVLIANAVGLALFERRREMGIFKAVGYSTAHLLRSISMEYSLVGLIAGSAGMLAVWLAITVINTLEPKAGLGLDALPGLLIFGFAIGLALLTALGVAWRPAHLRPLHVLRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL8</accession>
    <name>A9AYL8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX04996.1"/>
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    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2356"/>
    <dbReference type="EnsemblBacteria" id="ABX04996">
        <property type="protein sequence ID" value="ABX04996"/>
        <property type="gene ID" value="Haur_2356"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2356"/>
    <dbReference type="eggNOG" id="COG0346">
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    <dbReference type="OMA" id="GFVKKHD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2384-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:dioxygenase activity"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
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        <property type="entry name" value="VOC"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14127" checksum="31DC3B47198CB57D" modified="2008-01-15" version="1">MQIKMTSVFVDDQTKALKFYTEVLGFIKKVEVPVGEFLWLTVVSPETPDEVELVLEPNNHPAAQAYQAALKNDGIPCLSLAVKDIQAEYKRMQGLGVEFRGPPAEMGPTLATTFDDTCGNWVQMYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS2</accession>
    <name>A9AYS2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2410"/>
    <dbReference type="EnsemblBacteria" id="ABX05050">
        <property type="protein sequence ID" value="ABX05050"/>
        <property type="gene ID" value="Haur_2410"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2410"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="IMCAFLV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2438-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="35204" checksum="8BE0012B37DCE6EB" modified="2008-01-15" version="1">MIILETKELAKSFRVRGRLVEAVKGVTMNVQAGEIFGFLGPNGAGKTTTMRMLTTLLKPSSGQATIAGIDLLQHSRQVREKIGYVSQAGGAEGACSARENLILQARFYGITPHDANVRANELLAALDLEQIADRPSSSYSGGQRRRLDLALGMVHKPKLLLLDEPTAALDPQSRAWLWAEVRRLNAEGTTIFMTTHYLDEADALCQRLAIIDDGRIVVEGTPDALKRQIVGDTITLGLQFQPEIGHTVQDLLQQQSYIHSLEYAEQTIRLVVDRGSEALPLILRLIDDANVQVQTVELSRPSLDDVFLKQTGRSLRESAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV9</accession>
    <name>A9AYV9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protease-associated PA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4367"/>
    <dbReference type="EnsemblBacteria" id="ABX06999">
        <property type="protein sequence ID" value="ABX06999"/>
        <property type="gene ID" value="Haur_4367"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4367"/>
    <dbReference type="eggNOG" id="COG5276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432577_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4420-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013211">
        <property type="entry name" value="LVIVD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08309">
        <property type="entry name" value="LVIVD"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732254" evidence="1">
        <location>
            <begin position="24"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="2">
        <location>
            <begin position="379"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="583" mass="63446" checksum="AB5EB2BDC1B5B7AF" modified="2008-01-15" version="1">MLFQRWSRYFSVAICLILIAACANQNATAIPATATINNNAGEQARSDKDGVNQRPTKTPRLAATATPTITGPHFEQVGSLRLKPPTSGRHADLTLYNDLVLLGTQPGSCPAENQITLIDVSDPANPELAGYSPSVKNASLEDMDVVRIGEQDIAVLGIQPCRAATKPGIQIVDITDPTEPLELARFETNLGVHELDVTITASGQALALLAAPTNNAFGTTPKPEDRGELWIVDISDPSQPTMLSRWGIDQKPDWQALDYADRTRGNFPGIFLHSVRASSNSQRAYLSYWDGGVIILDIQDPNQPIYLGQTPYPALAEGDAHSVVDWNDGQMLALNNEDFSNDQAKISHPALAEPDYAHELPFGGKLDAPLSAKVLALGQACDAEAEYPDFKGFFVLAEMAGCSIEQKLQIAQNGEAAALLIYANTPFEELQFGDDVDLIDDFDLPMFTISSTTAAALLSQPEAEATIESYFDGGGAIQFFDLSNPSQPVEVGRYNTPNSINETLRSNPTVHNSEVQGQYLYASWYQDGLRMLDISDPSQPKSVASWPLNNSPKVALWGVQVRDQFVYVSDFSYGLYILEFKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ42</accession>
    <name>A9AZ42_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase with Chase sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0940"/>
    <dbReference type="EnsemblBacteria" id="ABX03588">
        <property type="protein sequence ID" value="ABX03588"/>
        <property type="gene ID" value="Haur_0940"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0940"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_85_1_0"/>
    <dbReference type="OMA" id="MGDGAMI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-954-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007890">
        <property type="entry name" value="CHASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05226">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01080">
        <property type="entry name" value="CHASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="414"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="597" mass="63940" checksum="455BF609C09219F7" modified="2008-01-15" version="1">MLRSQQIRRGIWFSATGLACLLALLLSDSWGWRRQLDRSAADLLVRQLASYSPQPAIIIVAIDDQALSNETGFGRLTEWDRSIYARLLDKLHAARVIVFDMLFTGANPAGDQAFTQALEPLEHPILAVSRDNQTNQIIEPASQLVTGRVVLAHSDIIADSDGVVRRIQTHYDQTALYPAIALASAQAWWHLPAGLQIEPTATTLTNGVVIPVNNSSFMLNYAGSNHTYPQVSLLAVLNGEVDPALFNDKIVLIGSTAAALGDRYTTPTSALMDGVEIHANAIGTILNANALREQSSSSRRFITLGLVLALTLIAMIRRPWLLFSGMVIGASVMVISAVSALQQQLLRIDLASPLLAIGLTGLVMLLVQNNLQRQDHTQVLELFAKRTPPSVLSELLKAAERGQLQLGGERREVSIVFMDMRGFTNLSERLPPEAMMQIINTYLNLIAKALIGHGGTLNQYAGDQAMAIFNAPVAQPDHAQRAIRGAVAALEAIVAFNRSAAAQALPAQASFGAGINTGIGVVGNVGAHERYDYSVIGDVTNVAARLCGAAPANTIYLGPDTLAEDLGDLQSLIQPMGALALKGKEASLEIAAIVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ46</accession>
    <name>A9AZ46_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Propionyl-CoA carboxylase</fullName>
            <ecNumber evidence="4">6.4.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0944</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.3" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0944"/>
    <dbReference type="EnsemblBacteria" id="ABX03592">
        <property type="protein sequence ID" value="ABX03592"/>
        <property type="gene ID" value="Haur_0944"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0944"/>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018822_6_2_0"/>
    <dbReference type="OMA" id="YAYAECT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-958-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="3">
        <location>
            <begin position="266"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="516" mass="56139" checksum="36C73688ECC8AFCB" modified="2008-01-15" version="1">MTTTAEKIAELRRRREQAATTDPKAAEKQHARGKLTARERIERLLDPDSFVELDALAVHRSTAFGLEHKRILGDGVITGHGTIDGRQVCVFSQDFTVLGGSLGEVFAEKIVKVMDLAMRMGVPLIGINDSGGARIQEGVVALGGYAEIFYRNVVASGVIPQLSIIAGPCAGGAVYSPAMTDFILMVKGTSQMFITGPDVIKTVTGEEVTQEQLGGAMTHNSKSGVAHFAADDEDECFEQLRTLLSFLPLNNMDDAPIIEPTDDPNRMDDALQSIIPDQPKKPYDMKAVIELIVDDGFFFEVQPHYAPNLVIGFARLDGMPVGIVGNQPAALAGTLDIDSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTHQEYGGIIRHGAKLLYAYCEATVPKLTVITRKAYGGAYDVMASKHIRADFNFAWPTAEIAVMGASGAVSIIFRKEIAESTDPVATNAELIHNYEERFANPYIAAERGYIDSVIEPRETRPALIKALHLSRTKRQSLPPRKHGNMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ99</accession>
    <name>A9AZ99_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0997"/>
    <dbReference type="EnsemblBacteria" id="ABX03645">
        <property type="protein sequence ID" value="ABX03645"/>
        <property type="gene ID" value="Haur_0997"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0997"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_9_0_0"/>
    <dbReference type="OMA" id="CRGTFRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1013-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="189"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="351"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="49521" checksum="67909C4F786BCF5A" modified="2008-01-15" version="1">MDSSLSAMPVQARQARLIEHYQTVRQFSEYLCEPLVTEDYVIQSMPDVSPTKWHLAHTSWFFETFVLTQAVPNYQTLHPQYAYLFNSYYVTLGKRHCRPKRGLISRPTVEETYRYRAYVDQQMLALLIAMDAETFARWEPILDLGIHHEQQHQELMLTDLKHVFSENPLRPAYREFAPSNQQPAAPLRWLSYPEGIVWLGYEGQSFAFDNESPRHRQFVHSFKLASRLVTNGEYLAFIEDAGYARQDLWLSSGWYTREDAGWTAPLYWEQLDGVWQQMTLGGLRPLDLAEPVCHLSYYEADAFARWAGKRLPTEAEWELAAQTVPLDGSYADAGRYHPTALNLDNSTLPQQMFGEVWQWTQSAYSPYPGFQPAAGALGEYNGKFMSGQYVLRGASCATSRSHARLTYRNFFPPDARWQFSGLRLAADGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZB1</accession>
    <name>A9AZB1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1009"/>
    <dbReference type="EnsemblBacteria" id="ABX03657">
        <property type="protein sequence ID" value="ABX03657"/>
        <property type="gene ID" value="Haur_1009"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1009"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2682780_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1026-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="74" mass="8236" checksum="6DD50F4CC2A1D4E0" modified="2008-01-15" version="1">MSTSTTQLTASEHRVMQILIQGKTNKAIAHILQTTEGTIETSLHRIYSKLNVDNRVSATLTYLAIEPTKHARDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF7</accession>
    <name>A9AZF7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PBS lyase HEAT domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2463"/>
    <dbReference type="EnsemblBacteria" id="ABX05101">
        <property type="protein sequence ID" value="ABX05101"/>
        <property type="gene ID" value="Haur_2463"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2463"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288073_0_0_0"/>
    <dbReference type="OMA" id="SADHEGK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2490-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24783" checksum="69E90EC363F5746D" modified="2008-01-15" version="1">MERTPETIVQLVADLQHDDEFVRSQAAFTLGLFGEPAVPFLIPLLRSPQRDIRMRAAWTLGVIGAAAVPALLDLMEQKNRQLRIEAIRILGVIGQARVFNHLLVALTDFDPEIAARAARSLGKIGDPRAFHALVLALRHPDSDVRYEAAVALAALHVPDAVSHLQEALVHEDPRIVTTWGMQVREGMVRALEEAEKPHDHSLIEALMRLGDMLKANEQDDGETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI2</accession>
    <name>A9AZI2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2488"/>
    <dbReference type="EnsemblBacteria" id="ABX05126">
        <property type="protein sequence ID" value="ABX05126"/>
        <property type="gene ID" value="Haur_2488"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2488"/>
    <dbReference type="eggNOG" id="ENOG5030UB1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1169400_0_0_0"/>
    <dbReference type="OMA" id="IDACPCC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2516-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="27878" checksum="59DC5E82D1B14C7F" modified="2008-01-15" version="1">MLHSATMTNIIERLYQCFRGYTIPDHPTGCPCCVSADDYQRLRSKPLRQLTENDLWRYSLKALNTWGDEDQFRAILPRCLELCADRSSFFDRSMLFGKLRLAEWRTWPEPEHQLIQTYLWTLWQDSLNSLDESVDELLCAIAQTGLDLHPLLMSWDTQLQTLIGLERYADLLDRHMATIIDQNRLQGYGWPNSDATAISWVLDPTRREWMTTAFANSQHDDESRLLARILEWFDLYP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL0</accession>
    <name>RUVA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ruvA</name>
        <name type="ordered locus">Haur_2516</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RuvA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZL0"/>
    <dbReference type="SMR" id="A9AZL0"/>
    <dbReference type="STRING" id="316274.Haur_2516"/>
    <dbReference type="EnsemblBacteria" id="ABX05154">
        <property type="protein sequence ID" value="ABX05154"/>
        <property type="gene ID" value="Haur_2516"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2516"/>
    <dbReference type="eggNOG" id="COG0632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087936_2_1_0"/>
    <dbReference type="OMA" id="KAPAVMA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009379">
        <property type="term" value="C:Holliday junction helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14332">
        <property type="entry name" value="UBA_RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013849">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvA_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011114">
        <property type="entry name" value="RuvA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036267">
        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
        <property type="entry name" value="RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46929">
        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00084">
        <property type="entry name" value="ruvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000090324" description="Holliday junction ATP-dependent DNA helicase RuvA">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <sequence length="197" mass="20583" checksum="7967F251E1654A00" modified="2008-01-15" version="1">MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLALFGFSSPAQRALFELLLGVSGIGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKTAARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTSLGYSTTEAQAALNALPADAPADTEERLRLALQYFGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B016</accession>
    <name>A9B016_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMI1_KNR4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03723">
        <property type="protein sequence ID" value="ABX03723"/>
        <property type="gene ID" value="Haur_1075"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1075"/>
    <dbReference type="HOGENOM" id="CLU_1494291_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1092-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SMI1_KNR4"/>
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    </dbReference>
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        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20373" checksum="63D64E58DB0936C4" modified="2008-01-15" version="1">MYSTYMQELASFVVEANVVETVAGVDEAVIAELEQARGYRLPACYRAFLQTFGKTNTWRWFDGDYASIDRFDETLEVVQDLIAEGLIPWLDDRAIIPFTQHAGYVVYYIRCDDGDDPAVFCAISGDETTPAECSQLAPAFSIWLRNSAFDSIERRSWTEVKPISSTFGSLREQSMNEANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B053</accession>
    <name>A9B053_HERA2</name>
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        <submittedName>
            <fullName evidence="2">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1112"/>
    <dbReference type="EnsemblBacteria" id="ABX03760">
        <property type="protein sequence ID" value="ABX03760"/>
        <property type="gene ID" value="Haur_1112"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1112"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_612197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1133-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="119"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="447" mass="50374" checksum="F213F062D94EFDA6" modified="2008-01-15" version="1">MPASGEKFAQLLTEALYQIRLRESKPLQVIQDELGYAMGRNGGSVIDYWRRGNLPTKLADLEQLTRTLQQRGVHDQRWIETFLTAGGYPPTQTLIQPVAASKALDPNLPKRYRQLVGRDSLVRQVLQHLSDREGYWVIAIDGMGGIGKTALAMDLMQRFVAQQPEYRPIWISAEPQQGGGILPNQPLTFDSLITNLARQLALADVAQLSVEEKFQRLQQVLKHQPILLVLDNLETSGEPQQVLLEKLRPLLQPSKVILTSRQRFKGEVFSVHLIGLEAEQAALFIRQDANEKGVQWLQQASLDDLQPIIKATGGSPLAMKLVVSQLASLPLDVVLQHVQSVTQLNPGDEDAYVRFYMFLFQRSWTLLELSAKQLLVSLARFVPSNGCDWRAMQQISALPAAELAHSIDMLWKLSLLELNEGERFGQLRYYLHPLTQHFVLSEIAQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E3</accession>
    <name>A9B0E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2614"/>
    <dbReference type="EnsemblBacteria" id="ABX05252">
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        <property type="gene ID" value="Haur_2614"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2614"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="VYLCCKA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2642-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
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    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
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    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
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        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="26383" checksum="DDB5904CB1D22229" modified="2008-01-15" version="1">MTTFDLSGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAMACHTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYFWLIQAAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIRVNALAPGLIKTKFSSALWDNEDLNQKIVAGTPLGRIGTVDEVAAAALYLASDAAAFTTGTVITMDGGSLVGGILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L2</accession>
    <name>A9B0L2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4599"/>
    <dbReference type="EnsemblBacteria" id="ABX07230">
        <property type="protein sequence ID" value="ABX07230"/>
        <property type="gene ID" value="Haur_4599"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4599"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_8_0_0"/>
    <dbReference type="OMA" id="MGEHPRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4654-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="23713" checksum="16D3908A0BE48D38" modified="2008-01-15" version="1">MNQTTWDAVDQYISDRLVQADPVLDAALQASAEAGLPPINVAPNQGKLLHLFALMCGAKRILEIGTLGGYSSIWLARALPADGKLITLEYEPHHAEVATANIAKAGLSQKVEVRVGAALDSLAQLAEAKIEPFDLIFIDADKPNNPHYLAWALKFAHVGTVIIGDNVVRNGAVTDPSNPDPAIQGTRQLFDDLASNPKLTATALQTVGSKGYDGFAIAIVQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Q5</accession>
    <name>A9B0Q5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03775">
        <property type="protein sequence ID" value="ABX03775"/>
        <property type="gene ID" value="Haur_1127"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1127"/>
    <dbReference type="eggNOG" id="COG3039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100560_0_0_0"/>
    <dbReference type="OMA" id="PIKICAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1148-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="90"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="29321" checksum="6E4F2CE3A2823AD8" modified="2008-01-15" version="1">MRTDEIIIRLFCIVDDRLGAVKKHPLANLHPSEVVTIGLLLALKGRRYRSFYRWLSANYRHLFPALPEQSRRYRVLVKAHGYTDLFLADPTILGIIDSFGIELVHPRREGRSAAPLGKKGISNHRWIVGIKLAWLINQRGEVVEWSWMPANVSDQEFRDVVAWQEGQTIALGDRGFRVRADEDDGVPIKICARGDWNCRFLIETTFSLLERVFQIKQLTHRTDRGIDLRLGFVAACFNCLLQLTHGKLSFLDFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z2</accession>
    <name>A9B0Z2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2632"/>
    <dbReference type="EnsemblBacteria" id="ABX05270">
        <property type="protein sequence ID" value="ABX05270"/>
        <property type="gene ID" value="Haur_2632"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2632"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071272_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2660-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="38514" checksum="096BF4AE90F91942" modified="2008-01-15" version="1">MTIMLLSDHRAFPALRDQALPSLGIFTLHPTFNVEPIMNTPSVQRVHEAHSGVHVVIKSFEHKTGLDGRRFLPTYSRTLLNREATTLAQLHALGFAQAPYLVPRPLATDPERLLLITEWLPGQSWGSILETTLQTRNLGPLMAYVNTITGWLATLHRRTATTDKIDVTNAWEYWEKLLRQLREQELLNHAALANLRMLQVHWDASGVLHQGLRSMIHGDATPANMLFTAPEELALIDWERSRHDDPAIDIGCMVAELKHAFFNATGDPTAAEWLIRRVYDRYSLLSDFDQEEFAAFTQRGQFYMGCYLLRIARNEWFSWEYRQRLVAEAQACLVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B193</accession>
    <name>A9B193_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4649"/>
    <dbReference type="EnsemblBacteria" id="ABX07280">
        <property type="protein sequence ID" value="ABX07280"/>
        <property type="gene ID" value="Haur_4649"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4649"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_510715_0_0_0"/>
    <dbReference type="OMA" id="AHEGRIW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4706-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="310"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="533" mass="59816" checksum="498A1993C2E33F5F" modified="2008-01-15" version="1">MAANEPGQVTSPEDSYQRLRTEYERLQLLYSLAQQFATMLSLPNVLQHVLSATTRFTNAVRGSIFLYGEYDEVQMHLLSERFQQARLTPFTNRILREGLASWVLKHRQSALIADTNLDERWIDYPSDTLDVRSVLCVPLLRGRRVRGVLTLVHPEIGFFTMDDEALLNVIAQHAAMAIENAQLIADINDERRKFEGAFTAMEEGLILVDGDGRIHFVNPQALAFFAVTPPVPEHLNELSQQVLGLFKEAQQTGDSVRAEIVLEQNPTTDLAIHIAYIPIFSEQEDWWTIVLHDITRLKEYDRLKTQFVANASHELRTPLANIKLYARLAQQVKAKTKLPQYLETIASEAGRLEAIVEDLLTLTRLDSGLMHSSPEWVDIIELLRNLAQTYRPLAEAREQRLIFQECTSNLPKLWLAPDQFMRVVVNLLSNALKFTPTGGTVTLSVDRQTQAGQAGTLITVADTGPGIAPEHQQRLFERFYRGSNPTESGSGLGLAIVRELLALMGGTISVASTVGQGSQFTCWLPLEQHTHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J4</accession>
    <name>A9B1J4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NHL repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1231"/>
    <dbReference type="EnsemblBacteria" id="ABX03879">
        <property type="protein sequence ID" value="ABX03879"/>
        <property type="gene ID" value="Haur_1231"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1231"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_291144_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1253-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021720">
        <property type="entry name" value="Malectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039155">
        <property type="entry name" value="MLEC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13460">
        <property type="entry name" value="PTHR13460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11721">
        <property type="entry name" value="Malectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GSDH" evidence="8">
        <location>
            <begin position="77"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Malectin" evidence="9">
        <location>
            <begin position="780"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="959"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1049" mass="112261" checksum="499808F45710FEF9" modified="2008-01-15" version="1">MIKRQFHARVVVMIVIFSLLAGGLLLQPTIHDAAAQTRSTVQYSYNPERQHVHSGSISFFRQTIFNSSSALTGASLFDSPTGMIFGPDGRLYVSQFNGRIFAITLNPTNHQATAVQVIETIYNYPNTNDDGSPATGVNGRQLIGILFDPASTPSNMILYVSHSDPRYGYNSDTTSQKINTRSGTISKLVSTNNFATSTDIIKGLPRSRENHSTNSIVWGPDGWMYISSSSNTNNGAPSAHFSNLAEYYLSAAILRANVRDAGFPSAGIDVKNVNNAAALAPFAGQFEMYATGYRNVYDFIWLNNKFYANVNGGNDGYGDTPSAAQCPGGVEINPRYLPDTLKIVTQGSYGGHPNPARGECVLNNGNAQGLPTPPNYNPPALTYDFRPSTNGITAYISNAFGGALQGNLIVATYGQNQDVSRVQLDANGNPTGIQTLAKFNQPLDVVTDAKGVIYVAEFGSDAITILEPEDLPNCPPPPPYSSMVDSDNDGYSDFDEDQNATNLCSRASVPNDFDGDMISDLTDPDDDNDGILDVNDQLYFDPANGNNTKLPVEFNWNPGDAPLGKVANTGFTGVQITNGVTRTDEVKIAVGAAGGFTNIITTEGTNAGAINTQANALQIGFDPHRNFRVETRITEMFLGRTPEGDQAAGLFFGPNQDNYVKLVATANLNGDGTSGDTGLQFAMEVAGNLQINPTNNNPSMVLPGVSNIDLRLDGNPAAQTMTAYYKTDGGNWTAIGTINVPLWFFNTGTPAGILATNHGTPNTISFIFDFFRLSYRDIVARINGGDRDWTTNDGAAWSPDTSANRPYSTGGGTYVLIPGVSCPQIYNVTRDFDRLYCSERNTSGSAVQYTIPVSSTGTYAVRLHFAELYWGTNGRPGPNQRKFNVQLEGTTVLTNFDIFSETGATFRPITKTFTTNITDGAVNISLPTGQPGNVDQGKISAIEVWGPILNIANVTPTVTPSPTATNTPSPTATNTPTNTNTPTITNTPTNTNTPSPTSTGTVTATFTPTNTATPSNTPTNTPTETVTPSATATQGTATYRIWLPYTVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N3</accession>
    <name>A9B1N3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1270"/>
    <dbReference type="EnsemblBacteria" id="ABX03918">
        <property type="protein sequence ID" value="ABX03918"/>
        <property type="gene ID" value="Haur_1270"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1270"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_854619_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1292-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="201"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="35642" checksum="1BEC8B3252F1E761" modified="2008-01-15" version="1">MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKACRGVRLKRVLPSIELEQPQQLGDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTLLGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRLRDQQQQRDLAQANAQLEQTLTRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNHATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTRTTNDLQHALRLAFQLAGSRDHHMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B276</accession>
    <name>A9B276_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07426">
        <property type="protein sequence ID" value="ABX07426"/>
        <property type="gene ID" value="Haur_4795"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4795"/>
    <dbReference type="HOGENOM" id="CLU_2259904_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4853-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="103" mass="11789" checksum="29B0286652BBD2B7" modified="2008-01-15" version="1">MIKLLMSWNIAEGREQAHLEYVTSEFVPALMKHGAISDAWLSLGGTPEAPEMILGITSDEEIELRSFMQSNEWQELSAKLSRHVADFRYWFTNKIQNPGGFQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H0</accession>
    <name>A9B2H0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1370"/>
    <dbReference type="EnsemblBacteria" id="ABX04015">
        <property type="protein sequence ID" value="ABX04015"/>
        <property type="gene ID" value="Haur_1370"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1370"/>
    <dbReference type="HOGENOM" id="CLU_2382178_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1391-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="10861" checksum="6FD90B4048703AB1" modified="2008-01-15" version="1">MYAVYSIPPHELYEETVLELLPSYLRRMHNEREQQAMLIATKVGTMLFGDDTKGKGKSKRKQKQGSTTQPASTRSEVTYVSASQLIANMKARSVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y0</accession>
    <name>A9B2Y0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3407"/>
    <dbReference type="EnsemblBacteria" id="ABX06043">
        <property type="protein sequence ID" value="ABX06043"/>
        <property type="gene ID" value="Haur_3407"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3407"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065561_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3444-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="1">
        <location>
            <begin position="81"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="372" mass="41351" checksum="732E6CAE406A69A3" modified="2008-01-15" version="1">MSDTVLRLPAELKYADELRYLAERDNGQRPARWQLSPQMVRTFVLGSTPAQKLDREIAQKWYGDPSIAERAIVTLASDRGLLLIGDPGTGKSWLAELLAAAICGDSTYVVQGTAGTTEDQIKYSWNIAMVIAAGQSRDSMIPSPIMTSMQLGAMGRFEELTRCTSDVQDALISILSEKYISIPELRNDNVVFAKQGFNIIATANSRDRGVNDLSSALKRRFNFVHIPVVTNKKQEREIILFRTTELLERQQVRIDVAPTLLDVLLQTFADLREASASASSDDAKLESALSTAEQIGVLEDAVLYSTYFGEQRLTPEILGRSLVGTLVRRRPEDVAVMNKFWHSVVAKHSEKHQGEWRDFMAGGQDAMKVIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B360</accession>
    <name>A9B360_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4893"/>
    <dbReference type="EnsemblBacteria" id="ABX07523">
        <property type="protein sequence ID" value="ABX07523"/>
        <property type="gene ID" value="Haur_4893"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4893"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705733_0_0_0"/>
    <dbReference type="OMA" id="QEATTIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4953-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="280"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="40445" checksum="21338D1B743DC3FB" modified="2008-01-15" version="1">MIHSAAWLRQRHRRVMRGLRAYFGLQLGLSVGGALLLYWLGERPVSPLIIGSGIVVGLLLLPQARRWLGWLYIPSLLLTDLVHVTALLWLTPANALERGSLWALAYIPLLVAAGRWWSYSGGALALVAMLIADAAVLFGRLAWREALPVFIFQAVTAALGTWAAAHNESRTRRELLHSEAYHLSESRVNELTKSYQQTIQQLQNLRENPETSAIEQLRQQLHRTLRDVGGLPLAQRTLPEALAAELRTLKTEGNLSINYICDGHLPVLSPRATAYVWRAAQELLSNVRDHAQAQHLDVELYGDEATVVLQIRDDGVGFDPNLLRDDQHYSSLAALATQAEIHHGTFEVQSQPQAGTTITVRVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A0</accession>
    <name>A9B3A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1419"/>
    <dbReference type="EnsemblBacteria" id="ABX04063">
        <property type="protein sequence ID" value="ABX04063"/>
        <property type="gene ID" value="Haur_1419"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1419"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_0_1_0"/>
    <dbReference type="OMA" id="AWDSFFH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1441-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="211" mass="23395" checksum="CB20C010DE325CE1" modified="2008-01-15" version="1">MQSWSDDIQQQAAVFNAIGADYEVMFGNNQDQQDLSQWLADLLEPNSKVLDSGCGTGIPTAQTLAKAGHAVTCLEISASMLNLARQNVPNGQYVLDSVNHVNFEPASFDAVVSFFALLMLRRSDIEHALQQFHHWLKPAGLLLLSMVEGDFDYIQIVLGDQPVFVTAYPQAQLEALITKSGFQILETRLQHYVPHHGATPETQIFIVAQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E6</accession>
    <name>A9B3E6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04109">
        <property type="protein sequence ID" value="ABX04109"/>
        <property type="gene ID" value="Haur_1465"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1465"/>
    <dbReference type="eggNOG" id="COG5465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118111_0_0_0"/>
    <dbReference type="OMA" id="FDTYYPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1487-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="19746" checksum="B90FE3B42BA1E7D5" modified="2008-01-15" version="1">MEEPEYRPELDPEHEQAAGWRGFSTLGLFLEEDGWFPQRVEDRPAYRMHYQGANVDIRCLAQIKLEQEQLLIYAYAPMKVPEDKRQLVAEYLIRANYGLHIGNFELDFSDGEVRFKSSLDFEDETLTFIWIRNAIYPSVHLMNRYFPGLMMVMYGEKTPAEAITVIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F3</accession>
    <name>A9B3F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1472"/>
    <dbReference type="EnsemblBacteria" id="ABX04116">
        <property type="protein sequence ID" value="ABX04116"/>
        <property type="gene ID" value="Haur_1472"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1472"/>
    <dbReference type="eggNOG" id="COG5617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022594_0_0_0"/>
    <dbReference type="OMA" id="AELYWHT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1494-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="723" mass="81822" checksum="7B939CE8598CF32D" modified="2008-01-15" version="1">MVQPWVTFNANSAWLWYNRAVILEIEAHYMGRRVASWVWVLGLYSILAIGLTWPLITVWDSQIPGQAHKDGLEDAYQNIWNLWWMRQAISQPTNPLITDRFFHPETPNLYYHTLSPINTILATPITAIWGPIAGFNSLVLLSFIVGAFGAWKLAYDRVGSAWIALPAGVIFAWNPFHVASVVEDGQLQIFCLQWIPFYLLYAWRLAERGDRRSLGLAGLFLGLTIWTDWYFSLFLLLWTLGFGLWQFWRSEWPQRKRLFIQFGLLGIIGMLTALPLLVPMLIEASRADYMQLYPENDPVRLSADLAAFVVPARLHSLWGRFFSDLPSAINRRLYLGVVPLSLALIATWKTAKARPWLIMTLILAILALGPTLKLAGTTTTIPLPYRLIQQLPFISLARQPDRFMVLGMLTLAIASSYGLVWLSSKLIWQRTLALVIVVMIGIEYLPTPFDMRQPPMPQSLAQLPKTDDAALLELPFHEDLPYRDAERMLFQTVHGRPISGGYHSRLYPQPQYQLPVLRDLATLSQHPEIVQTAGNWQQQLATLNFGYIVGYKQQANGPRNYSPAQIAEFKQFVEANLGVTQPLAEDNFVVIYQVPQAQGVPIINLRDGWGKLEPSATGNYRWMGQAASLGLIVPEAGFYRLRWQATPAAIARSLQLSWHHNQLSIPISLEPRQYEVLIELPAGQTIVQLQTLEPATTGDAIANNGDQRLISLQLSNLQLISTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3G2</accession>
    <name>A9B3G2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1481"/>
    <dbReference type="EnsemblBacteria" id="ABX04125">
        <property type="protein sequence ID" value="ABX04125"/>
        <property type="gene ID" value="Haur_1481"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1481"/>
    <dbReference type="eggNOG" id="COG3889">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1081577_0_0_0"/>
    <dbReference type="OMA" id="VTVPWNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1503-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="29121" checksum="A7EE8FD0EF4C4A7A" modified="2008-01-15" version="1">MITAQRPSFSRFLLMSSLLTGLLIVLFAMTRWFDIPAGDVTDWLVGIVSVWWLLAITVIPWNIYFDARTVMADAEISQQRGIVVQASQQHYAKSIAKKSLVGAVLLHLVSAVALYGVAASDISSVGYIAAGAAILLTGLRPALRGYEYVAQRLATIHEEVRFPRDDIMLLKDKVATLEYKIEQLNLEEADSWASEQVKQAERLERRIEQLNVELQSLSTNNEVAHRQISREIEHAVAQISTDGQFLEHARELIRFFKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K2</accession>
    <name>A9B3K2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05574">
        <property type="protein sequence ID" value="ABX05574"/>
        <property type="gene ID" value="Haur_2936"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2936"/>
    <dbReference type="HOGENOM" id="CLU_1568609_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2968-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="18900" checksum="3391DE4E11E7659F" modified="2008-01-15" version="1">MILALDISAANLGMVVFERATARVVEHAHLDLDARRCTPKQRIILAVQSCQQWLRDYPKLVECVINAPLPKTQPADLIACQRIVGALIGLIYGTGLPVTEISLATAKRQLIGHQYTDRASLMLAAAMYFDADYSEYEASALALIVGYNQELFKRNKQQVADMRHFALLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K9</accession>
    <name>A9B3K9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2943"/>
    <dbReference type="EnsemblBacteria" id="ABX05581">
        <property type="protein sequence ID" value="ABX05581"/>
        <property type="gene ID" value="Haur_2943"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2943"/>
    <dbReference type="eggNOG" id="ENOG5032UAS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109394_0_0_0"/>
    <dbReference type="OMA" id="TIHRYEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2975-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20663" checksum="3B60BE8C74663EDC" modified="2008-01-15" version="1">MTKLWQPNPALLYHLSEDATISQFAPRPHPRKPEHPPIVWAIQGSLVANYLLPRDCPRICMRCDQQTSPDDQTRFFGLSNAQTIIAIEHAWLDRIRATTLYAYAFEQADFELADAAAGYWISFRHVDPIAMHPIDDLLGQLVSLGVELHVMPNLWRLHDSVAQSSLQFSMIRMRNATARSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L8</accession>
    <name>A9B3L8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2952"/>
    <dbReference type="EnsemblBacteria" id="ABX05590">
        <property type="protein sequence ID" value="ABX05590"/>
        <property type="gene ID" value="Haur_2952"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2952"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_764345_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2984-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="143"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="41315" checksum="C0FC3E68E3C7DEB0" modified="2008-01-15" version="1">MTILHSLGDISLAWLTEHLQPWLGSGMIKHMQLIEAHTPNSQLGHIQLQLFRTPIKAPRQLLLKINHEQHGAHEVAIYQYAQANDLNHLPFVPCFAASYDPVSGVSNLLLADLSETYEPAIDRQLLITGEHVPNEQRRFMCIDGLAQLHSSWWQAPVIGEANSPFAVHCWYNDSVAHAQHVQRRQTEWQRFLAQHGPILTDAIHDRLASTLAALPTLWQRWLEPRISSHRQLTLVHGACAFNQFFCPKNPQEDHAYLLDFSAASANLPTYDLVSLLATFWNPTQRAFYEEQLLRRYLAGLIGSGIDYSWQQLCSDYRLMLAYMLFEPIGNAIDGADQAYWWPKLQGLAAANDEWHCEQLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q1</accession>
    <name>A9B3Q1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_2985</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2985"/>
    <dbReference type="EnsemblBacteria" id="ABX05623">
        <property type="protein sequence ID" value="ABX05623"/>
        <property type="gene ID" value="Haur_2985"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2985"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042787_0_0_0"/>
    <dbReference type="OMA" id="AKHYWVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3017-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024026">
        <property type="entry name" value="3'-RNA_MeTfrase_Hen1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026610">
        <property type="entry name" value="Hen1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024740">
        <property type="entry name" value="Hen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038546">
        <property type="entry name" value="Hen1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21404">
        <property type="entry name" value="PTHR21404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12623">
        <property type="entry name" value="Hen1_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04074">
        <property type="entry name" value="bacter_Hen1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hen1_L" evidence="10">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_12" evidence="9">
        <location>
            <begin position="285"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="460" mass="51510" checksum="05F6F95ECF3B3A8C" modified="2008-01-15" version="1">MLLRLTTTHTPATDLSFILHKHPDRVQTFPLPFGSAHIFYPEASAERCTIALLLDVDPVALVRGNRGSEGMLSQYVNDRPYVASSLLCVAMGDVFSSAMAGICKKRPELVDLVLPLTVELPVVAVRAKAGLSLIQRLFEPLGYQVSAEPIANDNPANSYLALKLTANLTVKQLLTHIYVLIPVLDNAKHYWIGNDEVSKLLRKGDGWLAQHPECELITTRYLRYQKSLTSAALEHLLQAVAPETTTQTELDQEQVSEPTERQSLHTQRHNVIVQRLKASGAQRILDLGCGEGKLLRELLKESQFSAVVGMDLSTRALAILQQRIERLPERQRQRLSLLHGSLLYRDARLKGFDAAAIVEVLEHLELGHLAAFERTVFGFARPKLVLVTTPNREYNQLFPSLPADQLRHRHHRFEWTRAEFAVWAERVAASYNYRVSIEPLGPEDPNHGAPSQLGVFEDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3V6</accession>
    <name>A9B3V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3456"/>
    <dbReference type="EnsemblBacteria" id="ABX06092">
        <property type="protein sequence ID" value="ABX06092"/>
        <property type="gene ID" value="Haur_3456"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3456"/>
    <dbReference type="HOGENOM" id="CLU_773331_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3493-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="41179" checksum="63A3F3E6D83A1CA9" modified="2008-01-15" version="1">MAEFPTLQLHRQSLLNAFRDVQAKGLDTLRAYEWVKLARCAYYLRDPLASTYLQQAAAQQAIPMEFQIASLNFYRMAGDQAALQACFRQLPTKPAGSGQWAQATYQWAYFQALFWLGDDRECIKRYHHEASLQTIALAKILAQLAEARLNRNASQALAVAQRLAEAIREERLEPWSNLPLNLWDLYELSCQLLDPPLSIDAALIQATVSPAQRLLELLQAEQIVALEWAIYNNDDEADIGYRNYTLADGTTTSFGTGFVNQELERMVWDIMNVDWGVHIDPNQQFGIYRLEVAKAVVQYMGELWTSYDFEEMEADGSINETYLVVQHPTDPELYMMYLPEVQRQTVDLARWNGQKRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B400</accession>
    <name>A9B400_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3500"/>
    <dbReference type="EnsemblBacteria" id="ABX06136">
        <property type="protein sequence ID" value="ABX06136"/>
        <property type="gene ID" value="Haur_3500"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3500"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_0"/>
    <dbReference type="OMA" id="DPEQWAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3537-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="120"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="40353" checksum="89207458BFF2F939" modified="2008-01-15" version="1">MTVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLLGADKPWFLWYPTWLAGDTWMDKIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKLPDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTFSFIGLSLPAFWFGLLIIAVSLWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRFMRASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTETVFNYKALGFTFISALNLKDYPLAMAFLLISSILLVFATLLADVLYTIVDPRIRLD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B426</accession>
    <name>RL6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplF</name>
        <name type="ordered locus">Haur_4929</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B426"/>
    <dbReference type="SMR" id="A9B426"/>
    <dbReference type="STRING" id="316274.Haur_4929"/>
    <dbReference type="EnsemblBacteria" id="ABX07559">
        <property type="protein sequence ID" value="ABX07559"/>
        <property type="gene ID" value="Haur_4929"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4929"/>
    <dbReference type="eggNOG" id="COG0097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065464_1_2_0"/>
    <dbReference type="OMA" id="KPDPYKG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144001" description="50S ribosomal protein L6">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <sequence length="179" mass="19466" checksum="0D395A1126DDCD45" modified="2008-01-15" version="1">MSRIGRKPIEVPAGVTVNVDSNNLVTVKGPKGTLSESIRPEVTVNINGATVEITRVNDSRQARAFHGLSRTLVANMVDGVTKGFEKTLEMNGTGYRATLDGKTLVLSLGFSHPVRVEPYEGNSFEVAERRVVIKGPNKQKVGDQAANIRKLRPPEPYLGKGIKYSDEVIRRKAGKAGKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B429</accession>
    <name>RL30_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmD</name>
        <name type="ordered locus">Haur_4932</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B429"/>
    <dbReference type="SMR" id="A9B429"/>
    <dbReference type="STRING" id="316274.Haur_4932"/>
    <dbReference type="EnsemblBacteria" id="ABX07562">
        <property type="protein sequence ID" value="ABX07562"/>
        <property type="gene ID" value="Haur_4932"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4932"/>
    <dbReference type="eggNOG" id="COG1841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131047_2_0_0"/>
    <dbReference type="OMA" id="GKQNQRD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_L30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000347104" description="50S ribosomal protein L30">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <sequence length="62" mass="7003" checksum="B434F1D3276235ED" modified="2008-01-15" version="1">MRITYKKSSIGYSQAQKDTVRSLGLRKLNQVVELPDTPVVRGMIFKIKHLVTVEEVTATEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P6</accession>
    <name>A9B4P6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1568</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1568"/>
    <dbReference type="EnsemblBacteria" id="ABX04211">
        <property type="protein sequence ID" value="ABX04211"/>
        <property type="gene ID" value="Haur_1568"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1568"/>
    <dbReference type="eggNOG" id="COG0498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_4_0_0"/>
    <dbReference type="OMA" id="GFTNKAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1592-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35518" checksum="BEA6B18C14822520" modified="2008-01-15" version="1">MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVMMSHILSHQVRQVIDDSSGNAGASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVEVEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWEMWEQLGRRVPAAIVCVAGQGGLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGIRIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQLTELAPDDIVIPLTGSGLKQAAVAELSMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R3</accession>
    <name>A9B4R3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1585"/>
    <dbReference type="EnsemblBacteria" id="ABX04228">
        <property type="protein sequence ID" value="ABX04228"/>
        <property type="gene ID" value="Haur_1585"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1585"/>
    <dbReference type="eggNOG" id="ENOG5033Y97">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_929686_0_0_0"/>
    <dbReference type="OMA" id="TPPWDAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1609-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="178"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="31904" checksum="BED528DA972EE61F" modified="2008-01-15" version="1">MATPVSQETKTDLKDVKPQAPAVPLLWRQLWIAGLLTGLVWCLVIFAPFSYMIYLAGVIPIGGGIYLGRKIQGRALVHGVIFSLIASATALLIGSILVFTLSAKPALNDPNQPVPTAQGNFLTLAMMVGMTLLPFPAYGTVMARRGQERTQAMRDEMSARGGQLERPGRVVSIEDLESLPLPKFGSWVAQLFRNNNFKLKNYKFNKDVIDLYLERNETAELWLVRCTISESLKPGQVQELYQDLRDNPEWHKGVIVTSLKVQDGARKSAKSRPNVEVLDGETLLEING</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y2</accession>
    <name>A9B4Y2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3067</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3067"/>
    <dbReference type="EnsemblBacteria" id="ABX05705">
        <property type="protein sequence ID" value="ABX05705"/>
        <property type="gene ID" value="Haur_3067"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3067"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104651_1_0_0"/>
    <dbReference type="OMA" id="PHPYVFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3099-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="21748" checksum="8974C54A92753E3B" modified="2008-01-15" version="1">MIEYLLQALGLGLAAGLLPGPMLGLVIRETLEHGRRAGYLVACAPLLTDAPIILIALFVANALPASINRWLGLAGGLFLIWMGIDAWRAKPPTEASGAPWASLWRALITNWLNPHPWLFWLPVGGPLLISIQRQHSWLATVSFLLVFYLLLIGSKIFLCEIVARSRRFLQGAAYRWVMRGCSVLLIGLGLVLIAEYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B592</accession>
    <name>A9B592_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3593"/>
    <dbReference type="EnsemblBacteria" id="ABX06229">
        <property type="protein sequence ID" value="ABX06229"/>
        <property type="gene ID" value="Haur_3593"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3593"/>
    <dbReference type="HOGENOM" id="CLU_1592318_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3632-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="167" mass="17944" checksum="4356ECCC30EC42F1" modified="2008-01-15" version="1">MDHWQTLHMATRLGVLDAPYPLRYLSIDDGVDLGRLLHAAAAPLPNEPTPTLSATIDWAFAALQGDYGRLLDACSFAIETRSGLLGAIVVVKQASTVKILQLAVAQAFQNQQFEPVLLSAALNALAQARYPQVQVAVLANSSQAHFFTAQGFMLAEDVNDASTSNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B8</accession>
    <name>A9B5B8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0091</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0091"/>
    <dbReference type="EnsemblBacteria" id="ABX02743">
        <property type="protein sequence ID" value="ABX02743"/>
        <property type="gene ID" value="Haur_0091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0091"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_0"/>
    <dbReference type="OMA" id="LDRHEHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-92-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="180"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="278" mass="31744" checksum="370BB37BAD2B7E7E" modified="2008-01-15" version="1">MQAPLNRETVHFWQDRVLNNLELLHAHYITQRFAPHSHEEFAIGVIEAGGQAFTYQRRSEWLMPAGSIAVINPQVVHTGHAATPQGWVYRMFYPPAQILQQAASQLAGRNQATPFFPQPVIHDPFLMQRLLQLHQLLEDPSTTALERESRLLWTMAQLIIRHAQSKPALSAQQLHPKAVTTIREYLAVHYADSISLEQLAQLVNLSPFHTLRMFRQATGLPPHGYLIQLRINQAKQLLHTQLPLAEVAVQTGFSDQSHLNRHFKRVLGVTPLQYRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B9</accession>
    <name>A9B5B9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0092"/>
    <dbReference type="EnsemblBacteria" id="ABX02744">
        <property type="protein sequence ID" value="ABX02744"/>
        <property type="gene ID" value="Haur_0092"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0092"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_1_1_0"/>
    <dbReference type="OMA" id="FIYMIVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-93-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="24808" checksum="B80E685A2AD89089" modified="2008-01-15" version="1">MHSISATFRAGIRAFLPIAVGIIPFALISGIAAMSVGLSIPQAIAMSMIVFAGSAQLVAMQLLAEHTPMLLIILTTVIINLRFVMYSASLADHFAQLKQRWKWLSAYLLTDQAYALAISLYQRKPHMHYKPWFYLGAAISMWITWQIGAVVGMLVGQQFPASWQLDFTIPLTFIALAMPAIKNRRLAAVALCAAIMAGATVMLPYKLGLVLSVLAGVGLGLYLEGRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D6</accession>
    <name>A9B5D6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0109"/>
    <dbReference type="EnsemblBacteria" id="ABX02761">
        <property type="protein sequence ID" value="ABX02761"/>
        <property type="gene ID" value="Haur_0109"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0109"/>
    <dbReference type="HOGENOM" id="CLU_513532_0_0_0"/>
    <dbReference type="OMA" id="SWHTITI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-110-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="606" mass="70074" checksum="6A9BF44811857AB6" modified="2008-01-15" version="1">MDFYAKACMGTFKLTSIKDRYIIVFGTFCIFLCYALFIFNSDVAYLAFTQPQDDSFYYFLPAWNFKAYGFYTFDGLNETYGFQPLWMVLLTIMAFFISSKILFFKLSLLVGCLFYLLTGLIIYKISKLLIRQRLLTFIPWFVWVSNIYLLRIFASGKENSLSVFLYALIALSLLNIHFKNRQQSSLYGLIDASFMLVRINNLMFVGPILLYRLYHNRQQKSQIGFYLATFSLVLSLWFGYSYAAFGTLFPNSGSLKTVISKPSIVYWLNQQTGVELGGMLSSQEQLLLQHPEFLDVPRANFFWQYLSQIVPQKVTDIYFDQKFSSITLVSTLNQVLLLSIGLGLIGFLGGLWQRSITINQQLIKLLSYCGIIALANSVVNWLFFQRYLSFTIWYPVPELFWFSLVLGLLVVASIIGWQQLSQIKPIIKPVQYIMLLAIGIFLLSPLSRFPQELLPQKTSEHYRGTYRFFSYIWQDEALKATSWANQALAPNTTIGSWNAGIVGYFYENGSTINLDGLANSPAFVDEVLRQNILFTRGLANENVLWNYIQHQDIRYIIDSWYSGEMGKSRFINSIPPEHYEIIYEGAVTFSDGNRPDRRMYVLKLKY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E6</accession>
    <name>RL33_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmG</name>
        <name type="ordered locus">Haur_0119</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ABX02771" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02771.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5E6"/>
    <dbReference type="SMR" id="A9B5E6"/>
    <dbReference type="STRING" id="316274.Haur_0119"/>
    <dbReference type="EnsemblBacteria" id="ABX02771">
        <property type="protein sequence ID" value="ABX02771"/>
        <property type="gene ID" value="Haur_0119"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0119"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190949_0_1_0"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000356484" description="50S ribosomal protein L33">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="54" mass="6514" checksum="31C9BC2D6739270A" modified="2008-12-16" version="2">MAKKENRIVITLACTECGDRNYTTTKNRKNDTNRLELMKYCPRLRKRTLHRETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5L1</accession>
    <name>A9B5L1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1601"/>
    <dbReference type="EnsemblBacteria" id="ABX04244">
        <property type="protein sequence ID" value="ABX04244"/>
        <property type="gene ID" value="Haur_1601"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1601"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469114_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1625-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="476"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="581" mass="64263" checksum="9F0B506AE964CD82" modified="2008-01-15" version="1">MSNKLKIDREQTQWRSSTILRSLPIMLIPIAVAIISLLWLRMKLPAEQFNQQPQRDGTPITAIVVIIMFVSALIIFVRLGRPTISAFALVGFWTLITTSLAVRSGITSFFPALLVLPICAAGLLIDRSASIGLAVLASLLVISLAWAKLQGYDLARQAPPSVFTRYPWLVSTVFWITLFWMVASMTWLLAGNLQRALQQSRAHAQDLEQLRSQLEQRVQAQTAELAQRTHRAEALYNISSALALPADITQILPLIAEQAHQLLHVDYSWIMLNHQCLAAYPEAAVHEPHLQFEPTQNTSVMSISSKFGEHTALVLPFQLENDQVQLILAGAAIAQTNTDDRALAEGLRDQAVLALNNQRLLAQVRDKAMLEERTRLARDIHDTLAQGLTGIVIQLGATQRALVYSPSESSTHLALASRMAREALAEARASVWNLRAPLLDANSLTKAIQELAAHPMRSDLQVDVQIHGQVLRLDLHDETALLRITQEALANVVKHSKAEHVSIQLIYGNSSVELLIHDNGTGFDQAILTNQMQMTNHFGLIGIRERVAQIGGSLQLSNQHGALVHVQIPYNLPQTALVEME</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T5</accession>
    <name>SYK_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="1">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysS</name>
        <name type="ordered locus">Haur_1675</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5T5"/>
    <dbReference type="SMR" id="A9B5T5"/>
    <dbReference type="STRING" id="316274.Haur_1675"/>
    <dbReference type="EnsemblBacteria" id="ABX04318">
        <property type="protein sequence ID" value="ABX04318"/>
        <property type="gene ID" value="Haur_1675"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1675"/>
    <dbReference type="eggNOG" id="COG1190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_6_0_0"/>
    <dbReference type="OMA" id="EIFGEKC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000101123" description="Lysine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <sequence length="492" mass="56253" checksum="41EAC065693F7EA9" modified="2008-01-15" version="1">MELNDLQQTRYGKLQALQAAGIEPYPARVPQRTHTLTAVREQFSALVEANATVTIMGRLRQRRVMGKSAFAHLNDDHGAFQIFLSKADVGDEPFKHFVDLTDLGDIIAVTGTLFTTKMGEPSVHVTSWTMLSKAITPPPDKREGQFSDQEARQRQRYVDLSANPEVREIFRIRARLITAMRRYLDERGFLEVETPVLQGIYGGAAARPFTTHHNQLHQDLYLRIATELYLKRLIVGGFDGVYEIGKNFRNEGVDRTHNPEFTMIEVYQAYGDYESIMQLTEGMIRFAAEQIFNSTSIEYQGHQIELGGSWQRLTMRDAIFEKTGVDIRECREFDTLWEAIGEAGLKIERKPTWAKQVDELFSEFVEPELIQPTFITEYPQPLSPLAKRKADDPQFVERFELFMLGAEIANAFSELNDPFDQEQRFLEQGRDYAAGDDEAMQMDEDYLEALKVGMPPTGGLGIGIDRLCLLFTNQTTIREVIFFPHLRKQGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z9</accession>
    <name>A9B5Z9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3155"/>
    <dbReference type="EnsemblBacteria" id="ABX05792">
        <property type="protein sequence ID" value="ABX05792"/>
        <property type="gene ID" value="Haur_3155"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3155"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_389261_0_0_0"/>
    <dbReference type="OMA" id="QMIVHAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3187-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033396">
        <property type="entry name" value="DUF5107"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17128">
        <property type="entry name" value="DUF5107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731911" evidence="2">
        <location>
            <begin position="27"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="717" mass="80227" checksum="7A6F07DC6CE5D975" modified="2008-01-15" version="1">MFRRITLSFCLLIVSLSFVPQRPSYAAFTDGFADSAFRQRWQRADQAVAEGQTSRSWVWGQNIGPRIIERYQQSPQASRLVQYFDKARMEISQPAADRTSEWFATNGLLVVELISGQMQTGDQRFEPRTAANVPIAGDPASSSPTYASLAPIATTNGDHRSENRQGQRISSLLAANGQISDQPNLATANTTIVQYESVTGHNVPKVFFDFQQSLSTVTNVLGTFGYPITEAYWIDTTINGQAQRVLFQAFERRVLTYNPNNSANWQVEMGNVGSHYYRWRYTTPMYYFQDSSIAAKVSEAGTLAINTEGYQPALVDSLPNDPIYPYKRIDRSKITGYQPKHYRLLKLENRYVTLTILPELGGRVYQLINKATGQNLLYQNPVIKASHLGQRGWWLAAGGIEWAAPTEEHGYLESEPWDYRLEQTNEAARVIVSTTERHTGIQIEITIELTNDSQIVNMRGNYRNPTASPQPFQFWMNAMIAPGGINHLQRSLHFAVPTQQMIVHATQDAALPAPQQTISWPTFNQRDLSRYATWNGYIGLFAADNLSGKWAGVYDPALNQGLMLVDLDPNLPGIKTFAFGDQFDRSLYTTDGSDYAELWHGAQATFWDYPSLAAGQSRSFEAHWLPLHDLGDLSAGNRYGAVGLQISSNGNVSVAIQPSQAFVATPIRISKAGQTLWQGTFDLKPQQPLRIELTQNITRGELLAIEWAGQTQQIVVP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B689</accession>
    <name>ARAA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">L-arabinose isomerase</fullName>
            <ecNumber evidence="1">5.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">araA</name>
        <name type="ordered locus">Haur_3664</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of L-arabinose to L-ribulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-L-arabinopyranose = L-ribulose</text>
            <dbReference type="Rhea" id="RHEA:14821"/>
            <dbReference type="ChEBI" id="CHEBI:16880"/>
            <dbReference type="ChEBI" id="CHEBI:40886"/>
            <dbReference type="EC" id="5.3.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the arabinose isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.4" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B689"/>
    <dbReference type="SMR" id="A9B689"/>
    <dbReference type="STRING" id="316274.Haur_3664"/>
    <dbReference type="EnsemblBacteria" id="ABX06300">
        <property type="protein sequence ID" value="ABX06300"/>
        <property type="gene ID" value="Haur_3664"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3664"/>
    <dbReference type="eggNOG" id="COG2160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045663_0_0_0"/>
    <dbReference type="OMA" id="HMLEICP"/>
    <dbReference type="UniPathway" id="UPA00145">
        <property type="reaction ID" value="UER00565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008733">
        <property type="term" value="F:L-arabinose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019569">
        <property type="term" value="P:L-arabinose catabolic process to xylulose 5-phosphate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00519">
        <property type="entry name" value="Arabinose_Isome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024664">
        <property type="entry name" value="Ara_Isoase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038583">
        <property type="entry name" value="AraA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004216">
        <property type="entry name" value="Fuc/Ara_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003762">
        <property type="entry name" value="Lara_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38464">
        <property type="entry name" value="PTHR38464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11762">
        <property type="entry name" value="Arabinose_Iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02610">
        <property type="entry name" value="Arabinose_Isome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001478">
        <property type="entry name" value="L-ara_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50443">
        <property type="entry name" value="SSF50443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0054">Arabinose catabolism</keyword>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000127608" description="L-arabinose isomerase">
        <location>
            <begin position="1"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00519"/>
        </source>
    </evidence>
    <sequence length="501" mass="55678" checksum="9EE75BA6A5EEC7B8" modified="2008-01-15" version="1">MLDLKQYEVWFITGSQHLYGPETLEQVAKHSQIIAAGLDQSSTIPVRVVFKPVLKTPDEIYNLVLEANAAKNCIGLVAWMHTFSPAKMWIAGLRSLQKPLAHLHTQFNSEIPWSEIDMDFMNLNQAAHGDREFGFIVSRMRLERKVIVGHWQDSEVHDRIAAWTRAAAAWHDAQGARFARFGDNMREVAVTEGDKVNAQMRLGYSVSGYGVGDLVRFVNEVSDADIDSTLQEYAEQYELAAGLQAGGEQHHSLREAARIELGLRYFLEHGNFKGFTTTFEDLHGLVQLPGLGPQRLMDRGYGFAGEGDWKTAALVRAMKVMSAGLNGGTSFMEDYTYHFGSNGMKVLGAHMLEICPSIAATKPRLEVHPLGIGGKADPVRMVFDAKTGPAVNASIVEMGNRLRLINSVVDAVETDQPLPKLPVARALWLPQPDLKTAAAAWIYAGGAHHTGFSFDLTSEHLADFAEIAGMEYLQIDRNTNVQQFKQELRWNDLYYHLAKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6A9</accession>
    <name>A9B6A9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3684"/>
    <dbReference type="EnsemblBacteria" id="ABX06320">
        <property type="protein sequence ID" value="ABX06320"/>
        <property type="gene ID" value="Haur_3684"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3684"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104166_0_0_0"/>
    <dbReference type="OMA" id="REMLYFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3726-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="16"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="21384" checksum="70C3F3A9AA0F33C4" modified="2008-01-15" version="1">MADQSVPYSHSELMIALERDVATVSDTILALTPEECFAHPEGVWSPAENVLHLQQLTKVLTLAFYVPRFTLSTLFGKPKHQSTDYLTIKTRYQAAIAKGFSAPAYSIPAKPQGSISLQAQQALVAQWQKLNQQLIETLFHWDEAALDQYQLLHPALGKLTVREMLFFMHAHTAHHLNDLAKLRQNHVASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G1</accession>
    <name>A9B6G1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0212"/>
    <dbReference type="EnsemblBacteria" id="ABX02864">
        <property type="protein sequence ID" value="ABX02864"/>
        <property type="gene ID" value="Haur_0212"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0212"/>
    <dbReference type="eggNOG" id="ENOG502Z832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112459_0_0_0"/>
    <dbReference type="OMA" id="IHQAVYR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-215-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="22904" checksum="BBF939DB9C6CD733" modified="2008-01-15" version="1">MTEQRIGEVIEASSTQWTTGAYELLNAPPFGSLIKAGCHDNDLCIYGLVYDIRTGSRDLGGKAMVRGGRRYDGSEFYDGQIYSEHPDLAAVLQTEWSALVIGYERAGRIIHYLPPQPPTVHYSVHLCDDDTVERFTQHCDFFRMVLHANLPIADELLGTAIRHAAALQANRREYELYAGRELARLLRDDYDRLRVLVRMLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H4</accession>
    <name>A9B6H4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0225"/>
    <dbReference type="EnsemblBacteria" id="ABX02877">
        <property type="protein sequence ID" value="ABX02877"/>
        <property type="gene ID" value="Haur_0225"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0225"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313597_0_0_0"/>
    <dbReference type="OMA" id="CATFPAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-228-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="53"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="25107" checksum="9324D78428A213BE" modified="2008-01-15" version="1">MLQRMQALVIWAFERFYHEAAFTYDLVAWLMSQGYWSQWVLAALPDVADQHLLELGCGTGYVQQARQDQPSLTIGLDESRQMLGLSRRRAPQATLVRAVAQALPYADASWSAVLSTFPAPYLFDRRTLAELQRVLTSDGKLYIVDGGSIPNSLYAMIIGLIYRLVFGRHSNPEAPTSQLDPRIQRLQEAGFRVNTHIKQVGRSQVQIFIAEKANQLIDIRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I1</accession>
    <name>A9B6I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0232"/>
    <dbReference type="EnsemblBacteria" id="ABX02884">
        <property type="protein sequence ID" value="ABX02884"/>
        <property type="gene ID" value="Haur_0232"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0232"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1122998_0_0_0"/>
    <dbReference type="OMA" id="NLRMAED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-235-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="25065" checksum="A9F4254F941E2FEE" modified="2008-01-15" version="1">MWKRIKDLIRAWLHALFDRAENPVTMADEYIRQLEAQYGEAKRATAMAMGQATRMEQKRDENRKQAEDWERKAVNALERGDEELARSALERKRHFSAAASEYATQSETQNAQVKDFRNSISRLELQINEARAKRDLIKAKTSRADSQEAATRALQNMQGSGELGDRLGAMEERIDDRLYKAEAMAKLEGDSLENKFRNLEQETSLESELAALKAKVNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N6</accession>
    <name>A9B6N6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1702"/>
    <dbReference type="EnsemblBacteria" id="ABX04345">
        <property type="protein sequence ID" value="ABX04345"/>
        <property type="gene ID" value="Haur_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1702"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533982_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1729-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="224"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="510" mass="57629" checksum="51B9A9B8B3F784D5" modified="2008-01-15" version="1">MTVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQANYQQANNLLQAIKTSPLELLPWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQIQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAIIHTEIHEQTKHQKHINLSLPKKRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNYADIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQYITYAERQGESMILEVIETAGSKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYEDAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSGLSNHAIPLRSHILQVRGLQAIGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWATPPGYLHNSWRIGTPDQTTDRLGFRCAADVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T9</accession>
    <name>A9B6T9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1755"/>
    <dbReference type="EnsemblBacteria" id="ABX04398">
        <property type="protein sequence ID" value="ABX04398"/>
        <property type="gene ID" value="Haur_1755"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1755"/>
    <dbReference type="HOGENOM" id="CLU_1029632_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1783-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="29606" checksum="966B99FFDBE8AA03" modified="2008-01-15" version="1">MIEQQIQQFNADVDHLLETGQLPSSADPDHQALLHLAQQLAQLRLQPSSIQQAATAQRLQQPSIRKQYSGGFMLKSKMRMALAVVMALVIATIAVPPLRSYANQILRQIGWLSVTNEPTKAEQLLTATEVPPIPDQPTATPPVLSDASPFNLTYLPAGYVAKPSYSGRYYANDSTPDSIYISVRSIEEGSSLGVGAASTTPITVRNTQGLYIEQAPLYIKAKEGKMYQEDLETVAVNLVLWEENGQIIIIESYVLDQTTLIQIAEGLEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U2</accession>
    <name>A9B6U2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ordered locus">Haur_1758</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1758"/>
    <dbReference type="EnsemblBacteria" id="ABX04401">
        <property type="protein sequence ID" value="ABX04401"/>
        <property type="gene ID" value="Haur_1758"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1758"/>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081254_7_2_0"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX04401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="201" mass="21426" checksum="1D2479EA266A97B9" modified="2008-01-15" version="1">MLIGLLSLLGYLIGGIPFAVPVVRLLSGQDVRSTGSGNVGARNSLRVAGAWAGVLVLVLDALKAIIPMLVADSMLAEQWPVGLVGVMAVLGHCYSPYLLLRSLKTPWQHWRHWLLSVGGQGLATGLGVISMLTPILALPLLAVGAFFALGLKRSSWAALVMIGAAPLATYLLGYVHFVWLSIAACAIIILSKLWQDYPFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z6</accession>
    <name>A9B6Z6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3227"/>
    <dbReference type="EnsemblBacteria" id="ABX05864">
        <property type="protein sequence ID" value="ABX05864"/>
        <property type="gene ID" value="Haur_3227"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3227"/>
    <dbReference type="HOGENOM" id="CLU_1037355_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3262-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="30811" checksum="4F1FF03D05C08B44" modified="2008-01-15" version="1">MGSDAEVFIFDYQMYTSSVVPAMQTFIKTSNAEPWLAAIIRASDELMLPAYREQYVYKFQHGADFQAHCSYLDKNWAWRGQHQSAKAWFANWQQRACRSTSCVEINQCALHQQGHLADELTLLLNEVVEQRCLGSSIFVGRTVTVRFHQAWLLQQGIEVEHPVNQLLDCLGQRGWVIGYGWAGSAEGIHGWLNPQETARLAYHLSKFELPSIQPTLEAMQQALRTFWNQDLREEYFPNVAFEALGLAFIRNLALLARQEQQGLLWRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z8</accession>
    <name>A9B6Z8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3229"/>
    <dbReference type="EnsemblBacteria" id="ABX05866">
        <property type="protein sequence ID" value="ABX05866"/>
        <property type="gene ID" value="Haur_3229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3229"/>
    <dbReference type="eggNOG" id="COG0565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056931_0_0_0"/>
    <dbReference type="OMA" id="PIMNLSH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3264-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="241" mass="25931" checksum="1ED2BADF7EF4FDF7" modified="2008-01-15" version="1">MNSTIFANIITVLHEPQREVNIGSTVRALLNTGFQRLRLVQPVAYSIERLDDMAHRSGPLVEQIETFASLGEALANVSYVVGFSGRSRGERQAVSLPEFAPTLTALAATAPVAFVFGREDRGLDNAAIEQCSQLISIPVDPSYPSLNLADAVLLALYTIRGLATSAEPLPSPDLADQASHELLLNLLDQLLTKLNFSRTAGQQASAVRVMRDLLARSRPSPSEIALVTAICRKMLAALPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B790</accession>
    <name>A9B790_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose/sorbosone dehydrogenase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3737"/>
    <dbReference type="EnsemblBacteria" id="ABX06373">
        <property type="protein sequence ID" value="ABX06373"/>
        <property type="gene ID" value="Haur_3737"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3737"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_586327_0_0_0"/>
    <dbReference type="OMA" id="WEETITR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3779-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="234"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="466" mass="50918" checksum="00E3989CE9FF5087" modified="2008-01-15" version="1">MLLNIATLVLLSLWLGAMIGGLLLMRQAGRWRWIGLAIAVQGLILLVFQGLLSTYPIGIGDPLIRVKFWDLLSQAAAVLGALVLVAFVLWWLAKQVRYSIDQQLHRRGLALLLLFGMPLIATPAFYAMWQTSIPERERERNPDLRVINVPEGFEWSVYARGTMDNPTAIAFGAENELYIADIAGDLWIGRDQNNDQQIDSLSKWAGDFDLLVGLVWRDGELYCASSGKIEALRDSDGDGVADSRRIVVDNLPSMILQPHSNNGLAFGPDGRLYFGVGSTTDGKFEENELAASVLSVNPDGTDLRPYARGLGNVFDVAFNADGALFGGDNGPSSVEGNDPPDEFNYLVEGEHYGYPYFFGDPPSDGGTRGALISFPAHSVPTGVTFYSGNQYPQIYSDSAFLTLWQTGEVVHIEVGQTSNGDYLAKSTTFADGMLYPIDVITGPDGNLYIADFGTSAIYRITYNGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B0</accession>
    <name>A9B7B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3757</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3757"/>
    <dbReference type="EnsemblBacteria" id="ABX06393">
        <property type="protein sequence ID" value="ABX06393"/>
        <property type="gene ID" value="Haur_3757"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3757"/>
    <dbReference type="eggNOG" id="COG4988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_0"/>
    <dbReference type="OMA" id="FPLNWAA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3799-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042883">
        <property type="term" value="P:cysteine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014216">
        <property type="entry name" value="ABC_transptr_CydD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02857">
        <property type="entry name" value="CydD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="336"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="368"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="540" mass="59340" checksum="FCAE0B2C8E9E2DE8" modified="2008-01-15" version="1">MATVEAQFKPNLQPSKAWLWLSIGLHSLVGLTTVAIAIGLTSIIAGVFRDGLGLAELWPWFGVMGLVVLLRFGLQWLAESAAQRFAQNVKQQLRQRLVGQMLMLGPAQGQQSASERVQILGETVELLDDYLAGYLPQRMLAAIVPLLMIAWVWPYDRLSAIVLALTVPVSVVMLVLVGLHTRDLSQQRWVQLRRLNARLLDLLQGLTTLKVFGRSRAQIQQIDQLSRKFTDATLAVLQIAFVSALVLELTASLSTAVVAVEIGLRLLNGSLQFYDALLVLVLAPEVYAPIRALGVQHHAGMQGLEAAEQINHFLAQPVADVEPVGKIQPVLGDLTVHNLAIHYAEDGPNVLQQRDWHFPQGQHSLIQAPSGAGKTSLVLAILRLIQPTAGEIKLGATPIDQLDLTQWRSMIAYIPQHPYLFNGTIAQNISLTKPAASPESIQQAAGWACADEFIAQLPAGYATLVAEGGANLSGGQRQRIAIARAMLKDCPIILADEPFAHLDRATAQQIRRNWAELWRGRTVIEFSHEINHEEREEHEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B3</accession>
    <name>A9B7B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3760"/>
    <dbReference type="EnsemblBacteria" id="ABX06396">
        <property type="protein sequence ID" value="ABX06396"/>
        <property type="gene ID" value="Haur_3760"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3760"/>
    <dbReference type="eggNOG" id="COG2234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688451_0_0_0"/>
    <dbReference type="OMA" id="THTEIWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3802-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="43216" checksum="B87B7B824F6FD4AE" modified="2008-01-15" version="1">MATQKKLLASRPQIALVKMSEQSVQQRITGALADEIGARPATSTAEARAAAVIAAQMRQVGLEVGVQTFSAAAAPTAGLGLLAAIGLLALGLGWWFPYPSVALIALLLLLAGRELHGPPVLAGLLRQRPSQNVIGTRAATRIPRARIVLLCHLDSPRMLSPRRASWLRVWLLTIPFGFSLSLIALGVAIFLPAWHSVLLIPAFFLLLSLLVVIRREWKADWTVGAVDAAAVGTAIALAADWPQREDVELWVVALGAGAAAGSGIQALLNTYPFPKAETWFVNLPWLGRGNLTIVAGEGLWRERKPDPQLTKMFHELQSASAPLIRSAYRGERLDSARLLAMGYHAVSVVGLKSDGTAAGFRQPDDETRLLSVPQMELALRVLRRVLDRFARSHSNEPQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y5</accession>
    <name>A9B7Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3281"/>
    <dbReference type="EnsemblBacteria" id="ABX05918">
        <property type="protein sequence ID" value="ABX05918"/>
        <property type="gene ID" value="Haur_3281"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3281"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_3_0"/>
    <dbReference type="OMA" id="IVTWLFM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3318-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="645"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="699" mass="73913" checksum="21062355783753FE" modified="2008-01-15" version="1">MSQQTISLPIRGMDCSSCALHIQTALGELSGVMQAQVLFSAEKALITFDDQLLEPNALVQTIEQAGYQVPQLQAAPPKSTPASARLLLLFGAIVVVVLGFSVLGEQLGWLDLLIDWIPWPIGVALVFVAGYRIFWRVAQAAWRKTVLSHSLMSIGVIAALAIGQWPTALLVVLFMSIGEYVEQFTSSQARRAVRELTALAPTLAQVERDGTEIQLPIEAVQVGDVVVVRPGDQIPVDGVVLRGAASINQATITGESMPIDAIEGTQVFAATLATAGSLRIQATAVGRDSTFGNVIKLVEEAESQKAEIQRIGDAFSDYYLPVVALIALLTFVIQRDPLATAAVLLVACSCSFALATPIAMLATIGAAAKQGILIKGGKYLEALAKTSVLLIDKTGTLTHGQPAVSQVVVHAATNEAEVLCWAAAAEQDSEHPLAKAIVRAARDRSIDLPHVREFKALAGSGVQAVVEGQTVVVGHQRLLGEHPLQAQANALEQQGQTVIWVLREQQVLGLIACADRLRADVAPAIAQLRRLGIDTIEILTGDNRAVAANIAEQLGISYQAELLPADKLAIVRRYQAQGHHVVMIGDGVNDAPALAQAHVGIAMGVAGTAVALDAAHIALLRDDWSLIPQALALALRTMRIVKGNLGFTVAYNVIGLSLAALGILPPVLAAAAQSLPDLGIMVNSARLLRYKPKPSSLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B870</accession>
    <name>A9B870_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myo-inositol-1-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3367"/>
    <dbReference type="EnsemblBacteria" id="ABX06003">
        <property type="protein sequence ID" value="ABX06003"/>
        <property type="gene ID" value="Haur_3367"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3367"/>
    <dbReference type="eggNOG" id="COG1260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050011_0_0_0"/>
    <dbReference type="OMA" id="GTKEWAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3404-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inos-1-P_synth" evidence="2">
        <location>
            <begin position="216"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="42769" checksum="F3FDA3748F25AA36" modified="2008-01-15" version="1">MDFNWSTIFPWIELSFSLLRSCVVLSKKIRVAIIGVGNCASSLVQGIEFYKNANEDDHVPGLMHVNLGGYHVRDIEFTAGFDINITKVGKDLSEAIFAEPNNTYKFSEVPHLNVPVYRGMTHDGLGKYLSQVIEKAPGSTADIVKILRDTKTDVVISYLPVGSEMATKWYVEQILEAGCAFINCVPVFIASQEYWRKRFEEKNLPIIGDDIKSQVGATIVHRVLTNLFEQRGVRLDRTYQLNFGGNTDFYNMLERERLESKKISKTNAVTSQLPYALPADSVHVGPSDYVPWLTDRKWCYIRMEGTTFGNVPLNAEVKLEVWDSPNSAGVVIDAIRCAKLALDRGVGGALYAPSSYFMKTPPEQYTDDEAHRRTESFIAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B0</accession>
    <name>A9B8B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-glucose/GDP-mannose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3827"/>
    <dbReference type="EnsemblBacteria" id="ABX06463">
        <property type="protein sequence ID" value="ABX06463"/>
        <property type="gene ID" value="Haur_3827"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3827"/>
    <dbReference type="eggNOG" id="COG0677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_3_2_0"/>
    <dbReference type="OMA" id="GHCLPID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3869-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="331"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="438" mass="48529" checksum="124F1488C3DC91CB" modified="2008-01-15" version="1">MSTFADLRSAIETRRAQVGVIGMGYVGLPMLARAGNVGFNVLGFDISAERIASINEGVSYIGDVPSSDLAALRNNKLIEATAQFERLRDCDIIIICMPTPLNEARDPDMSYIESATNEIAARLRPGQLIILESTTYPGTTVEVLKPAFDACNLSVGADYFLAFSPERIDPGSVNFKVHNIPKVVGGVTPQCNELTSLFYGHIVTAVTEVSSPAAAEMTKLFENIFRNVNIALVNELTLICDRMGLNVWEIIDAAATKPFGFMRFTPGPGLGGHCIPLDPFYLAWKARHYDISARFIELAGEINLTMPRFVRDRISHALNDQERSIKGSTVVLLGVAYKKDIDDYRESPIFKVMDLLAADGANVYCCDPHVTVFYDHHNHEYQTVPLTDELLQQAHCTVIVTDHSAFDYAKIVEQSRVVVDTRNATREVKSHREKIRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E3</accession>
    <name>A9B8E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3862</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3862"/>
    <dbReference type="EnsemblBacteria" id="ABX06496">
        <property type="protein sequence ID" value="ABX06496"/>
        <property type="gene ID" value="Haur_3862"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3862"/>
    <dbReference type="eggNOG" id="COG3237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167733_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3904-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="10714" checksum="1FAC06B380E628D5" modified="2008-01-15" version="1">MSNLGERIKGKAEEIYGDAKERLGDALDNEQMQAEGRATELKGEARQEAAKAAERLGGMADEAKGNLKQVAGDLLNNEQMQAEGIAEELKGEARRKANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8F0</accession>
    <name>A9B8F0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydroxymethylglutaryl-CoA synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3869"/>
    <dbReference type="EnsemblBacteria" id="ABX06503">
        <property type="protein sequence ID" value="ABX06503"/>
        <property type="gene ID" value="Haur_3869"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3869"/>
    <dbReference type="eggNOG" id="COG3425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_7_0_0"/>
    <dbReference type="OMA" id="EDTLTMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3911-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01409">
        <property type="entry name" value="UPF0219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004656">
        <property type="entry name" value="FabH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00748">
        <property type="entry name" value="HMG_CoA_syn_Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="221"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="348" mass="36702" checksum="F26A7F884114EB3C" modified="2008-01-15" version="1">MRQPERPVGIVGYGAYVPRYRIAAQEIARVWAAGEGALPITSKSVPGPDEDTITMAIEAGRNALNRAQLDPQQLAAVWVGSESHPYSVKPSGTLVAEALGTSRWISAADWEFACKAGTEALSAGMGLVGSGMADYVLAIGADTAQGRPGDALEYTAAAAAGALIVGPAQQALATIEATLSYVSDTPDFFRRADRPYPMHGNRFTGEPAYFHHVSTAAKQLLAELGRTAADYQYAVFHQPNVKFPQTVAKQVGFAPEQCQAGLLAGEIGNSYSAASMIGLCAVLDVAQAGDRILLASYGSGAGSDAYSLVVTEALAAARNLAPRTSAYLKRRQLIDYATYAKWRGKIVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G2</accession>
    <name>RS15_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsO</name>
        <name type="ordered locus">Haur_3881</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B8G2"/>
    <dbReference type="SMR" id="A9B8G2"/>
    <dbReference type="STRING" id="316274.Haur_3881"/>
    <dbReference type="EnsemblBacteria" id="ABX06515">
        <property type="protein sequence ID" value="ABX06515"/>
        <property type="gene ID" value="Haur_3881"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3881"/>
    <dbReference type="eggNOG" id="COG0184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148518_0_0_0"/>
    <dbReference type="OMA" id="FKTHVKD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000143127" description="30S ribosomal protein S15">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <sequence length="90" mass="10455" checksum="8F910E215907E2DB" modified="2008-01-15" version="1">MSLEKDKSTVINNYKLHESDTGSADVQIALLTDRINQLIEHLKLHKQDHHSRRGLLKLVGRRRRLLAYLSKKDNARFRAVSERLGLRIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I0</accession>
    <name>A9B8I0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07644">
        <property type="protein sequence ID" value="ABX07644"/>
        <property type="gene ID" value="Haur_5014"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5014"/>
    <dbReference type="HOGENOM" id="CLU_2369014_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5077-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="10901" checksum="9983C30B710182DF" modified="2008-01-15" version="1">MTDDAHSSPQDYVTLTEAAAHYGFNYNALYKYVFVGRLAATWLEPDQIPVSIWQRMDVYAQANVTKKGGVWVTTHAQMQTYLESRKKGRRTDLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S0</accession>
    <name>A9B8S0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_C25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07734">
        <property type="protein sequence ID" value="ABX07734"/>
        <property type="gene ID" value="Haur_5106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5106"/>
    <dbReference type="HOGENOM" id="CLU_326456_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5168-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029031">
        <property type="entry name" value="Gingipain_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735378" description="Peptidase_C25 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="3">
        <location>
            <begin position="477"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="857" mass="90880" checksum="A7AAFA5B24C755FD" modified="2008-01-15" version="1">MRVYNYVLVLMLLVAVPRAALAVATPLTVTTADQTVVLAGVPSQPTTVAVRGLHAAAPSLTITMDTTTLPEADPARWADLPTSPVTLLRSGRYRGYGVWVYLVQPMIQQRGQIQQVTQLHAVLDGAVLVASPADLQALPRVPFGDPVPPTNPLALADHTWTLTVTEPGMQRVTGAMLAAAGIDLTTLTPATVQVQHHGVVLPLDWRGVGDGVVDAQDEVRLWVDSVGDRWNRASTLWLTTAPATPSPPMASRLALASTAPLTDTVWMTQTWDDPQILDSRHAGMRGWHTFSTRLSSLAGGDAQTMTIPVTATLPLASGLMTVTLRGATATNLPVPLVVNTVPLTVPATAAWQTTLAVSTSAAITVTLPAPAIGAASVLLETITVTRPTRLATMPTDPWESGSTPARYALPDAPPLRTLYDVTEVQSPQIVILPAGPTPVLADPLVNRRYLLVGASPLPTPTLTRHTPIVLLTVGSDVIIAPRAFLPALDPLRTPTTVLVAREDLDAAWAFGHVSPMAIRTFLQHAAATWPSPPTSVLLVGDGTTDPRDVLGYGQPPLIPPYLAEVDLWLGETACEACYGQLDGADPLSDLLPDLPVGRWPATTVEDVTALIAKQQRYAAAPWGAWQSTVGSLADNAEGALDFPQLAAQSEAVYPLTMTLHRAYYAPQATSIAPAWHEADARAVRERVLAIWQAGAMLMQYTGHSHAYQWAVTDPVVEPRGLLDLNAVGDLHNGERLPLLLALTCLTSAFHQPSPRGTTLDEALVLHPDGGALATWGSSGLGVAHGHDHLQHGLVTAALTMPRPTLGQVTEAGVLELALTGHCCTDALRTTLLLGNPATVLRVAPTPQQVWLPLVGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y6</accession>
    <name>A9B8Y6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07800">
        <property type="protein sequence ID" value="ABX07800"/>
        <property type="gene ID" value="Haur_5172"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5172"/>
    <dbReference type="HOGENOM" id="CLU_1127855_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5234-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="28605" checksum="DA149A95EA8279BD" modified="2008-01-15" version="1">MDDLDLHLALEALRTNPAAHVYHERITRGMQAIEQGTLTPFERDALHRLLARFPVSTPPAADPVAALIAAFQDKLPTYDPAAVATAVQHALAQRPATLNGAPVTITMDSDTHAHQANLAIGNQVGGHLVQVTVTIPIPDARFDALLATALRTHEQEKTLARIRHAAQQIESDRLLKLRLEGFVGRVTELAAIREHIETMRPTGGYVLIKAAAGEGKSSSIAKLIQEAGIAQTPHIGINLSRSQQLRPTTAALSMAVFDVSAPAPTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B953</accession>
    <name>A9B953_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IV secretory pathway VirB4 protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5240"/>
    <dbReference type="EnsemblBacteria" id="ABX07867">
        <property type="protein sequence ID" value="ABX07867"/>
        <property type="gene ID" value="Haur_5240"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5240"/>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_359337_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5302-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="779" mass="86252" checksum="6C7EB752DCDF6EE7" modified="2008-01-15" version="1">MNQQPLCLTIDPFSVRQYREELPQLEQRFANFWAGITYDARLISCTRRFSFAPIRQRLRQQTSPLDDLRDLMPMLVSAQEDGSRNAALTSLVQKRLATYERATAALQDAPAVHAAFRAMATGASDATTLAVVADGCRRALWPWRWLKNYRRAYEVMEREGNPLGIQHYFVAWPSEYTDAEAVRSVLKGTFLLPDVQSAPLPPLFHGKYREMATYLTPLDEGRPYLRVIHAFDVRGEWDLGSMQELLGGEEELAVALDVTTLPRAKAQRATTDAFNVLEGALTARNAVKDSRSERAYRDVSYAMNQLDVQQLHEVAYAILIQAPSVRDLNRITQTLRDRMGARLKLDVLSGTQGEYLKLFTTTPSKQIAAPLIRRNALSEHVAAKTPWGIRKSDATSGVLFGYDPHDQLPYHYNLFGATGTDNPHLLMLGKSGSGKTVSLGMLALRHAVAGHQIVMFDPVGNCARLCEAVGGGAAYYHLAEDVAINVLDPMETSLHRQKSHVERKLSMVLGRAITSGSGVQLRPREFSNAERGALDAALASTRIYGPDGVFLAQMDDDTAPLLSDLVLALRETKRPVGQALAEEITDIALQSQAHLFDRQTTLKWDFGSDVVAYNLNNADKALLPLYLDHGIGALNHYIRSPERRARGQKLVCVVDEFGILSQIESLKKEVANATKEWRNYGAALWSCDQNSATYMGGSGNAQDFNNLTTNNTAVKLFGRQEGTDANLLGEAFPELSPSDIAAIRTAGPGEFVGIFGTNEVHHLRMQLTDQEVAHFIRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUA4</accession>
    <name>A9AUA4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-ketoacyl-acyl-carrier-protein synthase I</fullName>
            <ecNumber evidence="3">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.41" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0372"/>
    <dbReference type="EnsemblBacteria" id="ABX03023">
        <property type="protein sequence ID" value="ABX03023"/>
        <property type="gene ID" value="Haur_0372"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0372"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_4_2_0"/>
    <dbReference type="OMA" id="GTACFDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-375-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="2">
        <location>
            <begin position="109"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="239"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="34969" checksum="A8994771881AFDEC" modified="2008-01-15" version="1">MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAAQQALANANYALDSIDLIVVASAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFMLALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALFGDAAAAVVLERGDGSSSLQHSQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLAELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVAAGRIQRGNRLVLLGSGAGITLGAVALIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC0</accession>
    <name>A9AUC0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase D/Transphosphatidylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0388"/>
    <dbReference type="EnsemblBacteria" id="ABX03039">
        <property type="protein sequence ID" value="ABX03039"/>
        <property type="gene ID" value="Haur_0388"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0388"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038053_0_2_0"/>
    <dbReference type="OMA" id="HASRSYF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-391-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="406" mass="47184" checksum="B21B5A33334B945E" modified="2008-01-15" version="1">MPFESFQDLITMLVVILVLQVSLALLLIGVRKWRPTRYQRYPRISLPPTSDERHQFQLYMSGEELFPAMLQAIESAQRLILLETFIFKGDDLGHKFREALLRKARSGVAVYVIIDGFANLVVPRKFKNFPPEIQLLSYPAFPRLSQIFDIGSYARDHRKLLVVDNEVAFIGGYNLGELYRTEWRDTHVQVRGPIVSNLAEMFASQWNRYRRRLTRLHIDLELEWQSTVRVQRNDAGRLVFPIRSMYLDAIERAERFVYISNAYFIPDRAILEALVLTARRGVDVRILVPAESNHVLADWLARHYFEFCLRHGIKIFLYENAMIHAKTATIDGIWSTVGTANLDRLSLAGNHEINLEIYNAAFAERMQEIFACDMANARELTLAEWIKRPWYTKAAELVLSPLWPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUG8</accession>
    <name>A9AUG8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0436"/>
    <dbReference type="EnsemblBacteria" id="ABX03087">
        <property type="protein sequence ID" value="ABX03087"/>
        <property type="gene ID" value="Haur_0436"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0436"/>
    <dbReference type="eggNOG" id="COG3694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071040_1_1_0"/>
    <dbReference type="OMA" id="KPADAQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-442-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="29829" checksum="3E1CF03AC7C3BD5D" modified="2008-01-15" version="1">MLRYSKIYWYFVVQRFKILMEYRLNFFIGSISTVLFQGASIIAMWAVLRQVPSIQGWTLEQILLIYGLLTLSKGINHLFADNLWVIGRDYIRPGQFDRFLVRPINPLFHLLADRICHDAIGDFIVGFGLVGYAMVKLQLPITLASISFIILMVISGGIIFIALNLITAATAFWIMDSIPVTNLVFSTNEFAQYPLTFYHRSVGILLTWLLPYGFASYYPASYLLGHSIGWMAWLAPLIALVSITIAYRFWVFGLKHYGSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS0</accession>
    <name>A9AUS0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1954"/>
    <dbReference type="EnsemblBacteria" id="ABX04597">
        <property type="protein sequence ID" value="ABX04597"/>
        <property type="gene ID" value="Haur_1954"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1954"/>
    <dbReference type="eggNOG" id="COG1201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001338_1_1_0"/>
    <dbReference type="OMA" id="LLTNYMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1983-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="910"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1695" mass="190493" checksum="67D03265723E7DC9" modified="2008-01-15" version="1">MDIFQLRNQIIDQYSQYTQGFLSILDPEIQQFVTSNIQGGSLWPDALIQLSPAYQQGGTVEDLVNAQKLHPLCQYIFQKRDRQQQLRSLKLYSHQITALGLAQEKRHYVVTTGTGSGKSLTYILPIFDHVLKHQPEQGKVRAIIVYPMNALINSQMAAIKEFLGHLGDACPIRVESYTGQDKEATKRAIQANPPHILLTNYVMLELMLTRPDEAPFVDQQTANLQFLVLDELHTYRGRQGGDVALLVRRLRERSGNPELICIGTSATMASSTVADDRKSAVAAIASTIFGVNIPASQIIEEQLIKSVIFFGQPSASQLRETLLQPIPATMEWDTFKYHPLAAWIEQTFGITTDQTNTLRRAKPKTLAQGAQALADETGVDQAHCLHQLQAMLQLGSTVEDALNGRQAFTFKLHQFISQGGTIYATLAHPPERKLTSEGQHTIGDRDNPQLLFPLVFCRNCGQHYYQCNYDAHRQTLLPRQPFAQSHEQSTSMPGYALLGEDVWSDDAIEMLPDSWFNKSTNGRGTVKKDFKQFIPQRLTVRTNGSLGNEHDPTAWFIPSPFLSCLNCGTLYTKRESDFSKLARLSSEGRSTATTVLALATVQQLRQALPEQPAAQKMLSFTDNRQDASLQAGHFNDFVSVAQLRAAIYSAVRQQPAGRALDYTTIAQAVFEALNLPQTAYAKEETTLPNKRAKIDDALIRLIEYRIYEDLRRSWRVTQPNLEQVGLLQIDYDGLDDLAQQTDLWARHELLAATPSHQREQILRTILNYMRNGLAINAPCLQEQEQKRMVTSIEALLQESWQMNEREFTSAKRFIVPTPDGRGSGDGQSLGASSALGRFLRAEQTWPSLTKTLSEKEYWPLLEVLVEALVGNILTDVGTGASRELQISRDALLWRAGDGTPPPPNLARSRMLKGFSPAPRPINRFFQNLYQHMAHNLQAMESREHTGQVAQAKRQDREQCFSAGTLPVLFCSPTMELGIDIGDLNVVHMRNVPPTPANYAQRSGRAGRSGQPALIETYCSVGSGHDQYFFDRQPAMVAGVVAPPQIDLVNEDLLRAHIHAVWLSKTGLGMQHSMLDLVDTSQVGYPLWPAIQAQIHLSPPQQAQCIEACQRIIDQCQIDLATLQSFGPQYVERTLAEAPMQFDAACERWRELYRAADEQVREARNLMDRGHQRSGRSPEADQARRRHGEALRQKDILCNQSRSESGSDADFYPYRYFASEGFLPGYNFPRLPVRAFLCDHTGDGEYLSRPRFLALTEFGPRNIIYHEGKQYRIIRSALPATNAQQRFIQAKVCLICGYFHNDSAVQLDVCSNCGARFDEKTSELLPDLLPMSTITAQSIQRITSEEEERMRFGFTISAHYQFSRDHVGFRRIAARTKTTALSLDYGHAATLWRVNHGWRRAKMKGFSIDLQSGLWAKNPEEDSTTFDPTNETRRNVRLVVNDTRNMLLVQPTPELADNSEALFSLQAALVRGILAIFQLEAQELEAQVLGYQADRRMLLWEASEGGAGVLRQLVEDPQALARVARAALEICHFDPNTGAEQIDQAGECVRACYHCLLSYSNQPEHAYLNRHAIRDMLLQLTHDQVEHEGGLDETSLERLLAQTPTGFVREVLEWLDQNGQRLPDAIEPELQGGRPHLFYAASADSPSTCVLCIEADESLDGLRWDLEELGGYKVITLHRDQAWQQQIIGQQPFTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS8</accession>
    <name>A9AUS8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1962"/>
    <dbReference type="EnsemblBacteria" id="ABX04605">
        <property type="protein sequence ID" value="ABX04605"/>
        <property type="gene ID" value="Haur_1962"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1962"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1991-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="422"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="538" mass="60102" checksum="1D3A0C8B4DB2856C" modified="2008-01-15" version="1">MGSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDYYGMDKQQLQDVIDADFNQPDYTQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTKHAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRIIDNVPGMVYQLLLNPDTTISFPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVINGHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAAGQIQYLNPAARHVIQSEPTTAAEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQTAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQADAERQRLHEEIIRTQQQALIDLSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVAGLLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF1</accession>
    <name>A9AVF1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LamG domain protein jellyroll fold domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1999</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1999"/>
    <dbReference type="EnsemblBacteria" id="ABX04642">
        <property type="protein sequence ID" value="ABX04642"/>
        <property type="gene ID" value="Haur_1999"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1999"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_224181_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2028-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1103"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1136"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1183"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1223"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="6">
        <location>
            <begin position="1687"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="domain" description="LAM_G_DOMAIN" evidence="5">
        <location>
            <begin position="1687"/>
            <end position="1821"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="6">
        <location>
            <begin position="2369"/>
            <end position="2508"/>
        </location>
    </feature>
    <feature type="domain" description="LAM_G_DOMAIN" evidence="5">
        <location>
            <begin position="2369"/>
            <end position="2503"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="6">
        <location>
            <begin position="2656"/>
            <end position="2792"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="6">
        <location>
            <begin position="2976"/>
            <end position="3112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1482"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1501"/>
            <end position="1519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3907" mass="424593" checksum="75CB7DC2ACB9D53C" modified="2008-01-15" version="1">MRWLNTLTPWRIVGLLTLLCLGLAGLARSPQALPTSADPIQRAWQLAQISGSYRYSIDLAQTTTAAPSLANAGANPQRSERLSINGTIDQAADRMEMTIANNAEQNVSNSFALKIEQGRSFGRYGTGNWQPIEQSSDLFAPAGDPLGFLAGLEQVTSLGKETRNVGNLRLEFQHYQFNFNGEQFATYLQPKLEAQLRQRGELPVGMSLDTSTSYAQMNGTGEVWLDQHGLPSRLNLHLNLPAQADGSNVSATIRSDFFDFDQRRLALASSSFWQQPDRWLGYRLDQTQRQLQPLAQIALIPCLEILLLALAVVFWRKRRTQTLMAASVISAMLITPMLQAENVAATRSKQLAKQAEQTEQQAQAELQQQAMTKTQNLWQPNTKPEAQALSPKQLASNGSDSDGDGLSDADEDDWYSCATLGSSTGYCAGVSNAKDYDGDGLSDGAEVNQLGTLPRNSDSDGDSIPDGLEVKGFRYQGQQWYLDPLSNDSNQDGLLDSVDCGIWSQTSNAYNPNAICPDTDGDGQPDLFDRDNDNDGINDDVDLSPNLLSSAVFDDQNPLKLQIDNLKTNRPVFVDFQLRPTDLEHLSYSSRILDWPANDNQGQIQRVLDTTFATSTNSDIRINAINADYGDVMMVPMLEITMPYSTGHYANLPITTTYQNNQRQLGVGVEQWLDSSELDPYGITVRDLDTNSGNLLAYVPVVRVSNSMGGNPAAFAARMLYYPEQGSNGTANWGAAQQVRLVWLVQMITDECVDAEADPSTCARQENLSIVQIYDEAWSLAGMSVSEDHGAKTAIMYEQPSSDSNLQLDDELWMVAWNLNNTFIRGRDCDTLNGTTCQGNGQRDVRINNLASQIASWSSNSSNIAVQTSNFLHEGYLSQISMQQISDLLETQFNSYSSQTNPSLLIAQEKSNRSLNLQDGAGLSNGLARFDLNPSTIKLTTIAGMSWATYQFINGAWQNYAIDDYLTLLETTLRTNQTFIQHEVGEELSGKLIWAQLFYASINQGFLGLAEIDSVPVWKPSADALTEQDYQATWFVNPSPSGGHGFAATANLYAEQLQKVYKNLRKAQSTSNKWAKFDRTLSHDKIDPTSLQGLKTVRAATNYAIGVSIGLTLLGGTLLLIGLTTNNAALIKTSQIILTAASMLLVVTRITMIVSQMTAVVRAGSTLISTLSMLQSVAKANRSLGTVNLVIALTMIWGVFIFQLASGQFGWGSHSANLALAQAIAATIMIFVMLVIAFIPIIGPLIVAIISLVDLILRLFNIRGFSDWMSQFIADQLYEANNLLDNLSDPNRLNITSKTIDLLYPELGFVRSNALSMTFAVTNTLKYNDHFDVGDARRSTFRYWLQRSATDQHAALGQNQMRNEWDAIGNRQIQTSAEISLPEALPFSDVGTGINRSLGQQLFITEASVAPYEGCWLVATIEVDCTWYDTKGSSHSNIGEFQYFDILPDTIEQFANLDWNMNPDLRFNQIKDADGDGLISQALGGVDPDDTRFDSDNDGLSDYVELSNGTNPQNGDSDQDQLSDFEEHAYHTNPLNRDSDSDGLVDYVEFKQGWLVAYSDLSSTQTKLARIWSGNSSDADNDSLSDLEEYTFGFNPWVATDPSLIDNLVEIERLSVNEQNAPRLLAQFGEREQSQAFADSSGANHTLRCSPSQCPSLAIGRYANGVKFDGTNDQLNSNVGMLELAQASFTLAAWVKTTSTKQAIITKNDGDSTWERGEKSFYINANGQPTFVGFGNNYITSNQSVNDDRWHHVAVEWDYPNLTGTIYIDGIDRTNRTSTNYRTNNRDNANDTLKVGRNNSNSNEAANNFKGLLDEVAVFDRTLGTAQINDLMQGRYNPNDRLLAPGAALSYQATISNTLPAQSVNGQLSASNQTSDPDLANPNIALRMETLDRQQSYRNSAGSNETAYCLGQRCPTSELLGGRDYAVRFDGIDDQLSIPMQLDADVATGEMLRSLKFSIKLEQLPASGQTATIYSSVVSATSDLQIVINSAGNLVISVGGSTSSSYYNGSTTDSTWRKPHYSVYSFANNLNMWVEVQLDYRNFSDTTGRTTLSINGTQDSRLDYSYWPRLNIGNARLGANANSKAFQGSLGYLWATNEKNVRLLDLNFNEDYGYTGNYYHNTAGNQQALSCGTSSTCPSYQLQGYNGQAIRLDGNDDYLNLPNSASFTPGERTLRMAVKLEQLPASGQVVSLLDTVCANSNSYCLDLTINSSGQLIMHISPGTTLTSSTIFSQANLNTWVQLEFDFVIAFNSSSRSSVMVYANGSLVLIDSQFSIGPLELAPSRIGRSVANTNPLKASIDDLFIQGSYNLSFDAPPFDSEMRNHVNQARVASCEFVLTCPAFEQNGRYDQALSFDGLNDSLLLDRSISEDFSISFWLRSNQTSGAASNWWQGTGLIDANVLSPSNDFGISLGNNGQVMFGLGNSNGTSTTIKTRAINDNQWHHVVATRHKQTGAIKLYLDGTLAISGTGHLNRLDIPQLRIGAALNNSNFYQGQLDELVIIPAVIERDAVQFLMQSTYPAIKIDADFAPFHLPAQTSMVVSSTAQVNPNIISSQQRFEQEAEAAIALQQNIGYPVTDLNANKLPIFLPFEDVPGSQNFKNVGNVSYWSNLGYDKTNLECSNPDCPSAGLRGYVERAAYFDGNGDHLRFSDQCCSPEATTIAAWVNGNSGTIADLRNPNNATGLRLAYDNFLITIDLDGSTASGGNASFVVPFELPEGQWSHVVANYDKTNQLATVYINGQLAASTALPGANGTHASLSSQFPTIGANQGDGGDFYRGYLDDLRIYQVVLSASQIQSLYKTSAPILKFEFDEEQNTSEFHDRSQAGYLGKPITTQCATLDLESIRANQLATSPSTLYVAKANDRLASIRLNSQVTQPLSASSVLCAGDQLSVGLINSNGSTSLIANKTIDVAAIGNGSAIFQQGSNRITLRWAIDDQLLYRHNPAPGTDGKIGRTVLFDGKGAIQVDQANAINNLQNQFTILAWVKPDTITDTTSLQRFIAAGRDNSVNGFGFGLSGSALNFGIFGGFKYSSSATVAPRVWQQVAVVFDASNDAKFYLDGEYIDTIAGSSAVPANNDDPLFIGASTDQQGLFNDQFRGQLDELTIYQRELSTAEIYNLYLRDLRWYRARSTSYLTIDNDQPSVSLLASNHYRANAPFQLAVSATDPSSSIRLVDMGVRGPQASSYEWTSVAVCAEAQANNAAWCPVIDPSKFGGAGSYQVIFRAVDAVGHETTSAAATLYVDGAGPIATLEHNQNWRALQPVANHDLQWTLTLSGTIGDPQLGNGIAGSGLEQTKVLIGLFDQQNRLIGSESWQQAQVNGERWSINYQISGSRPSGSYRVEMSAVDQVGNQLTTALRANQAQQQSLLLDGRPPSVDLFQAIAATPLISETWQISGTLNELPSWHGAVASYHFETAAARNDSSGNNYHASCNACPSSATGQFGMAASFNPANQQRLTVATTASLNLSQASFSAWIKPNWNSSTGSAYSILALADSSNTRYNWQIASDYRSIRLFNGSTTNSISATITPNQWQHVALVQTGSEWTAYLNGTNLGSVEQSFGTTSNLPLQIGAAKPNSGFFNGQLDEVQIYERALSAREIYALAQSEHAGVNQAQIWLEAYHFDGSPSSEIWQSAPIQAQGTDLATWSYNPPAASEGFYQLHVRGNDAFANTNDERIIWRGSIDTQAPRVSINATQGGSGANSYTDYVISAEDLFIDENSLLSPCAGSPISYGYYPNPARINRLSVSCRVNGHSQSIVIVKACDYAGHCSTSSVDPLPTPTPTATAIPSATPIASATPTASATIIPSATPSATIVPSVTATGVPSVTPTAIATASTTAIASLTATATATLTATPSASPTATATATSTTTPTATATLTITPTKTATATAVPSITPSPTPTIVRWYFPWVTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH9</accession>
    <name>A9AVH9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2027"/>
    <dbReference type="EnsemblBacteria" id="ABX04670">
        <property type="protein sequence ID" value="ABX04670"/>
        <property type="gene ID" value="Haur_2027"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2027"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053674_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2056-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="46367" checksum="371BE46BC3B3E04B" modified="2008-01-15" version="1">MQQLSKRLNIPIAGLWLLAATFITTIGNGMQTFTIGLLLYDRTGSAAAFGGVIILEQGLTFLMQFIAGPWVDRGSPKRTCIQVEIIRGLFVCFASLMLGGDQVVLWIMLMTLVIRVAHPFYRAATFALAPAAIPRDSLGRYNGYTNISLQAGQLLGVIVASPVFYYLGPAVAFFINGLTFLFSALAVSFIQLTDHEVVAEAKAQVQNAWQQIIGGWGEVIGLLRREVGFIWHLLLNTIDAVAVHLFNLIAVPLIAARYNGSVYWLSVIECAYAIGAMISGGVVEPLSKRWGSRTSTMVGIGGQALCFMLLGFFSNQWLTILLCFGLGAFNTISWTVLMTTLQLRIRGAIKGRIGITRNLLTSLITAISIPLIASATNSSLNWALLLSGAICFGFAVLALVLGSPRFLGWRLLGEEPVAATTPAALAETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT8</accession>
    <name>A9AVT8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4056"/>
    <dbReference type="EnsemblBacteria" id="ABX06688">
        <property type="protein sequence ID" value="ABX06688"/>
        <property type="gene ID" value="Haur_4056"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4056"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_278586_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4099-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735025" description="DUF11 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="755"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1134" mass="116468" checksum="618482216006F9F4" modified="2008-01-15" version="1">MPRLVLQLALLAALIVRFNLPAAQAQPQAFVAPEELQAVADDQFWNNTGLIAGANNTIRAISSQSGDLFVGGLFDRIAGISANRVAFWDGDHWNTMGSGVNGPVDDLDASTGGSVYVVGSFSSAGGIAADGIARWNSGTGQWSALATNVNGAVTAVLVQQVAGSDVVYVGGTFSSIDGVSANRIAKFSNGSWSALSSGIGGGTAPQVLDLAINPANVNQLVAGGTFSSAGGSTANNVAIWTGSAWQSLGTGSSNGVNGAVRFVDFRGTNMVVVGGSFSNAGTVTNVGGAAVWTGGNTWAAMAGRGVTGDVRGIVENANFTYVMGNFGSGINPNGNSVFSPNIARWDGNIWSPVPNATNAFGTNGAILRAERLGSGSDTFFIAGAFGTAHGMELNFVGMVVPQQGFLPGATDRFFPLAGGLEGSNAKVFAIQPRSGEIIAAGRFDLGSNRLLNNIARFDPVDRVWSPLTGSSDSGVNDDVRDLALRNTDLIVVGEFSKAGGIDAAGVASWNGTTWTALATSINGRVNAVAISGSDIYIGGEFTLIDGVPANRIARLSGGSWQAVGAGTDGPVNSLLFKSNQLYAGGLFANAGGAPASNLARWNGTTWQAIGVGTDAEVLALADVNSTTVAVGGRFTSAGGVANTRAVALLNHSSLAWTALGTGTDGYVTSLVVRGDDLYAGGLFSRMDGLTVNHVARWNGTTWNALGSGVAGGNLQNSEVGALAVNGDNLYVGGRFDRAGDKVSHRFAEWRQPEVDLSLKLSESPDPVTIGNPMSYKATVSNLGTISASSVVYEQTFANTLVFGQVTTSQGSCSFPNSTTLRCNLGTLAANASANITINATPSQVGTISSTGTASSPANEAFPSNNSRSVATQVIVPGNPVPSISNITPDRFIRQPIGFPPPPAVRITVNGTGFVANSKVVVAGVERTTTFINSNRLEFSMAATTSQGTYSVLVRNPTPGGGDSNSVTLGVSVGIVGLSSITPNLGGTDVDLQTTFNVSWTHTTDPWRIIEHLDLRLVDSDGVALWARFTEGVSGTFSLLDANGDVLGYATAGSSDPLESDSAILDLADSNFAGSGPTGFSMQVNFSIRFKPSAAGRRYNIELYATDDHGGVQGPDVMGTFTVGIHDVYLPMTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU6</accession>
    <name>A9AVU6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4064</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4064"/>
    <dbReference type="REBASE" id="16538">
        <property type="entry name" value="M.HauORF4064P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06696">
        <property type="protein sequence ID" value="ABX06696"/>
        <property type="gene ID" value="Haur_4064"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4064"/>
    <dbReference type="eggNOG" id="COG2189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024927_10_4_0"/>
    <dbReference type="OMA" id="WPTKHDN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4107-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="32329" checksum="E6EB3CFA1702B5A0" modified="2008-01-15" version="1">MNKLYFGDNLAVLATLPAASYDLIYIDPPFNTGKIQSRTQLRTVRSEQGDRVGFGGHRYSSIKIGERAYGDSFDDFLAFIEPRLLEAYRLLKPQGSFFFHIDYREVHYCKVLIDQIFGRDSFINEIIWAYDYGARSRKKWSTKHDTILWYAKDPENYTFNYDQIDRIPYMAPGLVGPEKAARGKTPTDVWWNTIVSPNGKEKTGYPTQKPLAILNRIVRVHSNPNDQLLDFFAGSGSFGEAAARNGRNFTLIDQNPQAIEVMRQRLAFAEPEFYEIPKDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ8</accession>
    <name>A9AVZ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0588"/>
    <dbReference type="EnsemblBacteria" id="ABX03236">
        <property type="protein sequence ID" value="ABX03236"/>
        <property type="gene ID" value="Haur_0588"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0588"/>
    <dbReference type="HOGENOM" id="CLU_1068623_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-597-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="260" mass="27842" checksum="FADBBFAC507F69F0" modified="2008-01-15" version="1">MSDRPNEDKKLHDPKATVQLTADDLAAMRAELQQEKDKANQFATARLSEADIAPATNKKLENPYATVQLNPEEMAALRAEAQRVKAEAQAAQAAQAAPVAPAPDNISSMRGGAVANTPPAPAAPQSFPDQTVIMSPGQARAQYGNAPVDQSYAPPAQQQYAPPAQQQQYAPPAQQQQYAPPPQQYAPPAQQQYAPPPQPGYGQNYQNVQQTYNPPAQTGFSAPPAPLNTNENFFQKYGVYLLIGFGAMLIVAAILLLVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW06</accession>
    <name>A9AW06_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0596"/>
    <dbReference type="EnsemblBacteria" id="ABX03244">
        <property type="protein sequence ID" value="ABX03244"/>
        <property type="gene ID" value="Haur_0596"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0596"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1007505_0_0_0"/>
    <dbReference type="OMA" id="DQHTFAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-605-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="129"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="276" mass="30570" checksum="15090EC30F6193CF" modified="2008-01-15" version="1">MKPFNLMIYLDGSSAARRMVAYLAPLARKSHVKTTFLVDEAHQDEAEMYFFNAEQLLQSDQAPTRTIRGATPERAIVLETRASQPDLVAFGPLRKEGWRRWLGQSAIGSLARRLTCSMLLMQGRPNELRRALVCAAGGPATLHDAQMTASIIEPLGGQVTILHIVSQLSLTYKPEERDPERLADLVMEKQGEVARNIAAAKTILTDRGITTTVRIRAGMVLEEIQEELKTGGYDLLVIGAHRARTPLDRVLLEDVSAEILFNSPIPVLLVQNTSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWB5</accession>
    <name>A9AWB5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2125"/>
    <dbReference type="EnsemblBacteria" id="ABX04765">
        <property type="protein sequence ID" value="ABX04765"/>
        <property type="gene ID" value="Haur_2125"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2125"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_2_5_0"/>
    <dbReference type="OMA" id="GNICYGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2153-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="507" mass="53522" checksum="CFCAB3719A12C3A4" modified="2008-01-15" version="1">MTEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLGYTVAMPLLGRIADAYGHRRLFLAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLPIGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLISQIQLLDVDGWRWVFWLNIPLGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNLDQYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGMALIVGMVNVPFFVGTVLAGDALSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMITTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALSAAAIGTVARESMGTAAGLLNALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAAAVVCLIALIPIWWLPRERSEGDTPLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF6</accession>
    <name>A9AWF6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4083"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06715">
        <property type="protein sequence ID" value="ABX06715"/>
        <property type="gene ID" value="Haur_4083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4083"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_0"/>
    <dbReference type="OMA" id="WEFPPRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4127-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="45382" checksum="0545F15C93B7E0A7" modified="2008-01-15" version="1">MRVLMLAWEYPPHIVGGMGKHIAELVPVLDAAGIEVHVLTPWLRGGPQHERFGMHSHIWRVQPPAMPDYGFVSFTQETNRYLERFAHDLGKTHGPFDLIHGHDWLTSYCSVALKYAWHTPLITTIHATERGRGRGSLGGDHAKTINGLEWWLAHESWRVIVCSDFMADQLHQFFGTPFDKLDVIANGVNVPTIEWPSQERQQFRQKYAADNEKVVFSIARMVYEKGIQVLVEAIPHVLAQRRDIKFVIAGMGPLAEQLRNRSRELGIDAHVYWTGFVTDQDRNYLYNVADVAVFPSIYEPFGIVALEAMAAHCPVIVSDTGGLREVVQIHETGLTVYPDNPESLAWGILHTLSHPEWTQQRVENAFKTVVEIYNWPLIACQTQAVYQRVCDERATSMWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX63</accession>
    <name>A9AX63_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase superfamily 1 and 2 ATP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2231"/>
    <dbReference type="EnsemblBacteria" id="ABX04871">
        <property type="protein sequence ID" value="ABX04871"/>
        <property type="gene ID" value="Haur_2231"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2231"/>
    <dbReference type="eggNOG" id="COG1203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_367165_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017575">
        <property type="entry name" value="CRISPR-assoc_helicase_CYANO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03158">
        <property type="entry name" value="cas3_cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="36"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="778" mass="88907" checksum="469108B7039E1D3F" modified="2008-01-15" version="1">MITIQLTGHKEKLAPPNTIPNYRAAAPLLYHQVRTYQALEQAPLVMNTYATGTGKTTAASLRLLHPDQQKRNTLIIAPTNALIEQHCADAQAFIDDNQLAMRTLPINAATIRDITSETRRGEILQRLIANPLTFAEALGLPNDAEKLPFVAVTNPDIFYLALYFRYGPLDQRNVWEKFIRQFHYIVIDEFHYYDNKQFSNFLFFFNLWKEWGYFEAGYKICLLSATPRDAVYRYLNQVFGADGWQRVGPDNEPESSSALPPTPTLAPLTMHIHNDNLEEWLQTQSQIVADWQANALDSVIISSSLGKINRIHATLRQLNPIRITGPEPPEHRRLVRPVILATPTVDIGYNFGRPGKQRQSIDRLICDAKFGDELTQRIGRAGRVLGREQTDIPGEAHIFISEDAFGELKQWDTQTLNRAEWASIIHQLEHLPAKHQLEGYIRQYALLETFYPLLKLQQLTPKDDPDQEALFNAMRDIFAPNSQRTIGSLRHFYRVYEEREQWLRLSESAKWADRGAVAKHFAAQLSWLASTKDRQQEIKPEQVRGILDQRLIGHSTPQNALIDFIESQVVMTKALFNFREAWQGPKAAIYDPNQLLSSQTLTYFDLFHAFCHFDVTIYPSKTKFEQDAGSSESADVYLRINQLRPTPLGLAFEHPNTDQLDQTTFDDRYCNTIIGIKGLLLSAYEYGSRATVPIPTEIRNTVKSNAIPCLIVDQASTNALIRVLQGSPIYRQVLKVDFGGLFEEYTMVTGTAAFHVIPELKRHFLMRQKRVNDQPIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXA1</accession>
    <name>A9AXA1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4189"/>
    <dbReference type="EnsemblBacteria" id="ABX06821">
        <property type="protein sequence ID" value="ABX06821"/>
        <property type="gene ID" value="Haur_4189"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4189"/>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_266165_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="906"/>
            <end position="1245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1246" mass="138843" checksum="1267BB9BD1680A14" modified="2008-01-15" version="1">MTTAWLTQWLAKQRLNPQYQQGATLHQALQLVLYDWIPAVFEGLEQQAKANCWPDQDFSQRITASAKQLALWHGNPQRYCDLQQQQTNLPLQLPSSWQADQPTLSAKQIDALRSFCSSVSSDPRSASWTICVADEAELYACELHAHALFGDIAALWQPIIQGLAKLNELEAAISLILLQRDLADYAGIIASFKRAQQAHPKAAEQLVPWLDDQLKPALIDDLRAMLEAVLLAYRLHNPDDQTLLEALQQAIMALTPIEVAPDDGKGEEAPAPTPQRGVPLPAVNLPMPNILRFATPKNLLLNQLKTHWQALLAGVLVDEQLGARHRMVLQWWLAWTEHQLFNVTQAQALLAEIPSTTAPLGLLTEALRGELAFLAGQPELAQHCFATTLAASQQLISEPTFASQTSQNQAFGGLLAQWQGNSLVMLGDYTAAEQCYVKLANLLAADDREGQCLAAINRGNIAFVRNNLLDHRGYVTYDKTEQVLLRGDKPPEHFLGLKYTKHRQALVQAQQAYAEALNLAEQEPNLAQYRSLIIANQANIVWLQANLLLESSWFSSDLAASLQDLGEPAQLYQQALSLLQQALTLLNQTTADRVLQAVLFANISEVQLLLKQPAEALNSAQNCLKALNLSDLKPQAALKQAQMRGVLIPDAGWRVWLTMARAYEALNDLAKAQQAYANACDLVQVLRNNVQQSDWQMAALQDKFQVFECAMHFHFKHSSDRTSLLQLSENLRAHGFEQLLEASQIDRERELSPELKQQRLALAAALAARSMAIRLAMQQPAGDDLVKLLNDQRAAFADWQALQSSIAQALESQNQELQPQLITWPNLQKALAERPNTVILSFTIGSEWSYLLYTDGQQLQAFELACRAKIEYAVARLIWYAQRGAARWQEFVRANRHVVECLLGPLWAAGLKEQLRGKQLIIIPDGILYYLPFDLLFFDDPVDANQQPLDPATYRQKAPDQATPEQICRDLVPFYWLNHATISTAQSISLWLQLQQQAATQAANLALGVYNINYQTNVPSVYPGHIYAQELMISYNDLSQTSVLSKVLGDLAAHGTTLQLTAWQADHTPYQAEFQSNEANFKRILAEQAMRYIIFAGHGVFNDKYPQFSGLVFNLAAPDGSSDQSGQDGFLGIHDLFELRMPNTELIFLAACQGGLGLISRGEGINGLTRALMFRGSPTIIASLWSVDVLATMDLVEAYFELLSQQPTADKAEILTKAKQKMLAQPNKPHLVHPFYWAAFIPIGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI9</accession>
    <name>A9AXI9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0755"/>
    <dbReference type="EnsemblBacteria" id="ABX03403">
        <property type="protein sequence ID" value="ABX03403"/>
        <property type="gene ID" value="Haur_0755"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0755"/>
    <dbReference type="eggNOG" id="ENOG5032XGW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773328_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-767-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="40851" checksum="D37B63934A5406D3" modified="2008-01-15" version="1">MDSYQPSSDERQAMRAFLQRAEVRISTMHRIAGVFLNGAGLLILLPVFFRDAISDINKIVLTQIEQLYNLWQAGQFSWSATADLGLYILLFIPFIATLGIPLYAFLLLLKDIVYFYFANQSPGFTHKLFNPRFILSGLAFSTDEAPAVKRLVIQHQYNSDLLEFILPFERHEAAFYDHVYQQSAGLIVPPSRDPAQLASQGVNQSQVSQQAIDRFNTALGLSGFLDRTLIEEVARTEISVVRYALCLRRLVLRYIKALLMFVWTTLLSFILVSFLQHLQPLVILAVGYVVWSALTPLVVRMPTDWIWQALREDVNLKGVARDEEITRFERYVIRVCRLTLAIAILTLLSEIGRLIVHV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXV2</accession>
    <name>KDPC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kdpC</name>
        <name type="ordered locus">Haur_2278</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KdpC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXV2"/>
    <dbReference type="SMR" id="A9AXV2"/>
    <dbReference type="STRING" id="316274.Haur_2278"/>
    <dbReference type="EnsemblBacteria" id="ABX04918">
        <property type="protein sequence ID" value="ABX04918"/>
        <property type="gene ID" value="Haur_2278"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2278"/>
    <dbReference type="eggNOG" id="COG2156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077094_2_0_0"/>
    <dbReference type="OMA" id="KYFWPRP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-0633">Potassium transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000114727" description="Potassium-transporting ATPase KdpC subunit">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <sequence length="193" mass="20373" checksum="EC71FAA5FE34E198" modified="2008-01-15" version="1">MRTFFRPALAAIIIFSVLTGVIYPALVTVIAQVTFPGQANGSLIEQAGQQRGSSLIGQQFDQPEYFWGRLSATGPVPYNAAASSGSNYGPLNPALAEAVQARIDALKAADPSNQLPIPVDLVTASASGLDPEISPAAANYQVQRVAAARGLAVEQVQQLVEQHTSQRTLGVLGEPRVNVLQLNIALDQIKSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXZ9</accession>
    <name>A9AXZ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2325"/>
    <dbReference type="EnsemblBacteria" id="ABX04965">
        <property type="protein sequence ID" value="ABX04965"/>
        <property type="gene ID" value="Haur_2325"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2325"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_7_2_0"/>
    <dbReference type="OMA" id="FINYCQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2353-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
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    </dbReference>
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    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="135"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="35861" checksum="C802345FEF0E93B9" modified="2008-01-15" version="1">MQQLKWGLLGTGWIAEQFANALADLPNAQRWSVLSRNQASAENFAQTHQFAHAYSDQAAFLADPELDVVIIGSPHPRHAEQTIACLNAGKHVLCEKPMGINSQQVEAMIAAAQANQRFLMEAMWMWFHPSTIKAKQLIEAGAIGKPHLFHADFSVHFPFDPSHRMYDPALGGGALLDIGIYPLALALYLFGAPTSVYGQAQLGQTGVDEQESIILEYGDDRQANCVASVRAAGPCEATVTGSSGYIRFQRNFWHSQQLVVQNNGQPSETLDLPFIGNGYVTEVAHVAECIQAGLIESPIVSWAASRSLINTMDQLRQSWGITYPDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY48</accession>
    <name>A9AY48_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4298"/>
    <dbReference type="EnsemblBacteria" id="ABX06930">
        <property type="protein sequence ID" value="ABX06930"/>
        <property type="gene ID" value="Haur_4298"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4298"/>
    <dbReference type="eggNOG" id="COG3393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4350-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="15194" checksum="04ABC3AF42F6DB16" modified="2008-01-15" version="1">MPIEYKRDLDGIDWVQLKAELAGDDFDNGRTPEQYQRSFAASYSVCFALDGQRIIGKARALSDGVCNGYIVDVWTHSDYRRQGIASHLVKQILADLQGQHVCLFTDDMQTFYLQLGFAEETTGMSQVIGQWLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY76</accession>
    <name>A9AY76_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_4326</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4326"/>
    <dbReference type="EnsemblBacteria" id="ABX06958">
        <property type="protein sequence ID" value="ABX06958"/>
        <property type="gene ID" value="Haur_4326"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4326"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_5_0_0"/>
    <dbReference type="OMA" id="ITFFGWM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4379-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="766"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="791"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="837" mass="87908" checksum="8FC0E363570CBF80" modified="2008-01-15" version="1">MDTKTLTLPVTGMTCAACVTRVERNLKKVAGVAEASVNLASESATVAFDPAAVSPTNLIAAVEKGGYGVITAERTLPITGMTCAACVTRVEKALRKVDGVLEATVNLATETASIRYLPDQASLEQIKAAVTKAGYGVIETGEDDDAEDSETQARQAELKRKRSNLIVALILGVPLMIVSMMHDFSLISPIWLGSAREMTGMNHDMPAFYNLWPWLFGLMATPVVFYSGRDFLRGAWVNLKHGSANMDTLIALGSLTAYGFSLAVLLFKLSGHVYFETAAMIVALILVGKYLEAQAKSATSSAIRALIDLQPPTARVLRGGVEVEMPVAEVRAGEIVVVRPGEKIPVDGVVTMGQSAIDESMLTGESLPVEKRVGDSVFGATLNNAGSFQLRATAVGKASALAQIVNLVKAAQGSKAPIQRLADQISGVFVPIVIVIALLTFGLWYWVGGVGFTQSLIFAVAVLVIACPCALGLATPTAIMVGTGVGAQHGILIKNAESLERAVRLQTIVLDKTGTITEGKPTLTNVLALGDEANLLALAATAERGSEHPLGKAIVQGATARGATLGQASTFKAIVGGGIEAEVNQQKVVIGSPRLIREQGYDLSNIQTTIDQWQSEGKTAMVVVVEQQLAGVLAVADTIKASSPAAIQQLRKLGLKVVMLTGDNQRTAEAIGREAGVEQVIADVLPADKAATIKQLQANGTLVAMVGDGVNDAPALAQADVGVAIGTGTDVAIEASDITLLRGDLVGVAQAIELSRRTMTTIRWNLFWAFIYNVIGIPIAAGLFYNLTGWQLSPLLAAGAMAFSSVFVVTNSLRLKRAAKLQHGHGVESNELQPAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY95</accession>
    <name>A9AY95_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4345"/>
    <dbReference type="EnsemblBacteria" id="ABX06977">
        <property type="protein sequence ID" value="ABX06977"/>
        <property type="gene ID" value="Haur_4345"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4345"/>
    <dbReference type="HOGENOM" id="CLU_1560839_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4398-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19224" checksum="E2DA456FCEA53CDC" modified="2008-01-15" version="1">MSWEIGLVTFGSVVGLVIVLWVFSRLAWGGGMRNPSYELLNPSKEHPIHTHFAQPDQESIVVRCKQCHFSHTLPEISKMPAFLTSVARSSSESGELKSICPHCEGVLQSWIRQAIQHHGSQQTLDFAVLRRGQRRLYEIETTIYASLGEIPQPYRSLVAEALNEPEPEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH8</accession>
    <name>A9AYH8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0912</name>
        <name evidence="2" type="ordered locus">Haur_0915</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0912"/>
    <dbReference type="EnsemblBacteria" id="ABX03560">
        <property type="protein sequence ID" value="ABX03560"/>
        <property type="gene ID" value="Haur_0912"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03563">
        <property type="protein sequence ID" value="ABX03563"/>
        <property type="gene ID" value="Haur_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0912"/>
    <dbReference type="KEGG" id="hau:Haur_0915"/>
    <dbReference type="HOGENOM" id="CLU_2898059_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-926-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="62" mass="6367" checksum="E99F0C47E313485B" modified="2008-01-15" version="1">MSDVKNLIDAEVTAAETELFADELEEHVTNVAAACVSSLGSLSTSGTICTVSTFCTAAIEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL4</accession>
    <name>A9AYL4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ordered locus">Haur_2352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2352"/>
    <dbReference type="EnsemblBacteria" id="ABX04992">
        <property type="protein sequence ID" value="ABX04992"/>
        <property type="gene ID" value="Haur_2352"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2352"/>
    <dbReference type="eggNOG" id="COG0499">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_0_2_0"/>
    <dbReference type="OMA" id="NKYGCRE"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="187"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="295"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="45709" checksum="3CEA353F3ABB1B06" modified="2008-01-15" version="1">MAKDFDIKDIKLADEGMRRIAWAEQEMPVLRQLRERFSKERPLEGIKMSACLHVTAETANLMRALQAGGADIVLAASNPLSTQDDVAAALVQYDEIPVYAIKGEDNATYYNHLKAALDHAPHITMDDGADLVSAVLKDRRELLPNLIGSTEETTTGVIRLRAMANQGVLEFPVIAVNDSQTKHLFDNRYGTGQSTLDGIIRATNVLIAGKTVVVAGYGWCSKGIAMRAHGLGANVIVTEIDSIKALEAAMDGFRVMPMVDAARIGDIFITATGDIHVLDGEDFAAMKDGAIVCNSGHFNVEIDIPALEKMAVEKKQPRQFIDQYVMADGRRINLLGEGRLINLASAEGHPSAVMDQSFANQALASEYLLTNKGKLENKVYALPVEVDQEIARLKLAAMGISIDILTEAQVTYLNSWEEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYP6</accession>
    <name>A9AYP6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2384"/>
    <dbReference type="EnsemblBacteria" id="ABX05024">
        <property type="protein sequence ID" value="ABX05024"/>
        <property type="gene ID" value="Haur_2384"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2384"/>
    <dbReference type="HOGENOM" id="CLU_851983_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2412-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="37042" checksum="8845795999D26A34" modified="2008-01-15" version="1">MRQATHLNLPALWHPEHGVLFEQRAVSVARWVLPILALPPTNNLPRCINQQWLRWLAGWHGLPDAANTRLQLRIWRHAHGLSLSYVGMVWHEQASIAVQIAQTAARWMLGLLPTSYACQVIEQHDQLIDQLQDQWLRSLPYQAFVRLQHQAIVAQPFVSAYPNHAWQASLRALWASASPSLISLTVQPTQLYPEERAELQRQSNHPAAQLAQRWQHCWQRSLLVCSADPLLLVAGLQADHAPSSQQQLLEICLPQAEEHAAALAEVCWGNCEPWAATDWAYQRLAQLLANEQLVHWLSLPDLSPNERQTYHISSINSMEEPDATTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV3</accession>
    <name>A9AYV3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4361"/>
    <dbReference type="EnsemblBacteria" id="ABX06993">
        <property type="protein sequence ID" value="ABX06993"/>
        <property type="gene ID" value="Haur_4361"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4361"/>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_385325_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4414-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="46"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="717" mass="76693" checksum="79899878869A3C82" modified="2008-01-15" version="1">MTTRTLRIVLLLGLVLLFFGGSYTQARELQQPMPRSQTVLVPTTYINESFDSISFPPLNWSTTIITSTDTPDPEWTYVTSATRPTAQPHTGAGMAHFNSYSTINGNAARLSVVLTPTTSVLRVSFWYYHSAIFPTSADTLLLQTSSDNQNYITRASYPRYRATDGWTQYQLDLPFASAGQPFYLGFLGISDFGANLLLDDVLIQDTPPIEIFGTTSNQGCAGDTLLYPLSVRNNYPNAQTLDLNLAVSAWPSSLPFNQLAIPAQSSRPITVNVQIPATAQPHTSDQTTLQLSNGLVELNQAIVTNCALGQWIDREDSLVAARYSSVVSADGALFQIGGQGPNNNSPALANTLRYQPITGSWQQRAAMLTPVFGADAATLNGEIYVAGGYTTGGSTTTGLISSLQIYSPTLDTWRSGPSLPIALAYYQSAVVNGKLYIIGGSNGSNALTSVWIFDPIAQVWNAGSALMRARAFASAGVIGNKIYVAGGTATISNQTAMDTMEIFDPNLGFWMPAPNLPRRQMQGGDAQILDRFFVITTGYSMPVVASNSSLIFDQQTNQWSEVLLNSSRYGAEADSINDTVFVVGGRQFANNVFTMSSRNESFQICRFVLTTATPTPTATATSTATATNTPTNTATATPTATATNTPTNTATNTPTNTPTVTLTPTNTSTATVTNTPTNTPTVTATGSPTHTPTNTPTATQTLDVPDLFLPLVGVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ70</accession>
    <name>A9AZ70_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stage II sporulation D domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0968</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0968"/>
    <dbReference type="EnsemblBacteria" id="ABX03616">
        <property type="protein sequence ID" value="ABX03616"/>
        <property type="gene ID" value="Haur_0968"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0968"/>
    <dbReference type="eggNOG" id="COG2385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591565_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-982-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735121" evidence="1">
        <location>
            <begin position="28"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="3">
        <location>
            <begin position="171"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="345"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="422"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="462" mass="49936" checksum="EE92B49A5AA91C8A" modified="2008-01-15" version="1">MLRRLTWRWLGLLSLALGLLIQAPVSAQTRNQQRANLTVTVTNIDGKPLSNASVSVASLGLTTTTNEAGIAHFTVSTNDSQVIEVAVESQGHRAWRLRNAQLIPNDTLLVDAPLSLAAKAVDQQPEIIEVQAHRLTTNAPQEANLNDAELNQIMAGTNTTPPSTIRVYRVSLGRIDTVNFKTYVKHVLPNEWVAGWRTESLRSGAMASKTYAWYRTMYPKYPGKGYDTKDTTADQVYNPNVSYASTNAAVDDTWNYRLIKNNAIFQSQYCAGSYNGSRTSGQCSQNHGWTVGLYMSQWGSKYLADNGSSWRSILTFYYDNVTIGTISGGTTPSLPAWPSLRNGSSGNDVKAAQYLLRSHGYSLTADGAFGAGTEQAVRSFQSANGLTADGIIGPQTYAKLIKTVQNGSSGDAVRAIQTLLGVTVDGAFGAGTEQAVLNLQATYDLTRDGIVGPVTWQAAFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZB2</accession>
    <name>A9AZB2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1010"/>
    <dbReference type="EnsemblBacteria" id="ABX03658">
        <property type="protein sequence ID" value="ABX03658"/>
        <property type="gene ID" value="Haur_1010"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1010"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_103_9_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1027-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8104" checksum="79B0B59079D6ECEB" modified="2008-01-15" version="1">MHKLSAREYDVLALVDQGWSDAEIAKRLSISIWTVRTHLRSSASKLGVKSRQQAAHAARTLTAFQQAATAKNR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD9</accession>
    <name>THIE_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine-phosphate synthase</fullName>
            <shortName evidence="1">TP synthase</shortName>
            <shortName evidence="1">TPS</shortName>
            <ecNumber evidence="1">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="1">TMP pyrophosphorylase</shortName>
            <shortName evidence="1">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiE</name>
        <name type="ordered locus">Haur_2443</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZD9"/>
    <dbReference type="SMR" id="A9AZD9"/>
    <dbReference type="STRING" id="316274.Haur_2443"/>
    <dbReference type="EnsemblBacteria" id="ABX05083">
        <property type="protein sequence ID" value="ABX05083"/>
        <property type="gene ID" value="Haur_2443"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2443"/>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018272_3_4_0"/>
    <dbReference type="OMA" id="ITAFQFR"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000198079" description="Thiamine-phosphate synthase">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <sequence length="206" mass="21240" checksum="A9951F75578BC86E" modified="2008-01-15" version="1">MMQIDWRLYAVLDTATLGSRDPLAMTAALLAGGIGVLQLRAKNLSVRQTAQLAQAILPLTKIAQIPLIINDDLGLALAVGADGVHLGVDDLPLDLARASFKGLIGYSPEGVADAQRAEKLGVDYLGVGPFAATTTKLDAGAPLGQAGLRAIVEAVDCPVVAIGGIAQHNVAEVRACGVAGIVVVSALLNATNPTQACREFLAHYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B047</accession>
    <name>A9B047_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1106"/>
    <dbReference type="EnsemblBacteria" id="ABX03754">
        <property type="protein sequence ID" value="ABX03754"/>
        <property type="gene ID" value="Haur_1106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1106"/>
    <dbReference type="HOGENOM" id="CLU_1693089_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1126-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17799" checksum="34CE53FFC49A17A2" modified="2008-01-15" version="1">MLQAKYSSWTGRKLEIRSAYANQITVEFKGWRDSAQWQIEHTNYTLSRVKGKGYPLVMSANGQEIMRVARVSIWKTTLEGHYANQPLRFERPSIWKSGYQVYLNGVIIGEVKAEGFWQRTMIANFNNPQPYDFQLGCLMIAISIWRQEAASAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B052</accession>
    <name>A9B052_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAP domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1111"/>
    <dbReference type="EnsemblBacteria" id="ABX03759">
        <property type="protein sequence ID" value="ABX03759"/>
        <property type="gene ID" value="Haur_1111"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1111"/>
    <dbReference type="eggNOG" id="COG3942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1803539_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1132-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007921">
        <property type="entry name" value="CHAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05257">
        <property type="entry name" value="CHAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50911">
        <property type="entry name" value="CHAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735145" evidence="1">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C51" evidence="2">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="15368" checksum="BCACC241F95FEAEE" modified="2008-01-15" version="1">MMSRIFVVGLLVLMSLFSLMAVPLAAAKPQAAPAFCECTQYVYAKKGLSGSYGHAHTWDDSNGVLPRNGYRQYSIPQVGDVVVFSQAAMGNQYGHVAIITAVAPNYGPISVRGANQGGSETEGNCNNVNTRSYSRNGATFWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B061</accession>
    <name>A9B061_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PGAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2532"/>
    <dbReference type="ESTHER" id="hera2-a9b061">
        <property type="family name" value="BlEst2-lipase-like"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05170">
        <property type="protein sequence ID" value="ABX05170"/>
        <property type="gene ID" value="Haur_2532"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2532"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038340_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2560-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735372" evidence="1">
        <location>
            <begin position="29"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="547" mass="57680" checksum="5BEAE76EB9229534" modified="2008-01-15" version="1">MKRRIAVILALIALMLATVSLPHKSVQAQAAHLTAAPAPRIIAEVNGAGKGRVWVGAVPANSSSKPVLVFVHGLHGKAPNWWGATMYHGTNDMYDKAYAAGYRTAFVSIDDEVDGPASSIWVNGATLNRQLDVILSHYGVSSVNIIAHSKGGVDTNSAVIHYGASGKVQNIVTLSSPHRGSQLADLAYSWWAGWLASLLGQRDDGTYSMQTAYMSNFRSQTDGSANYSNVRFHTAGGTNHGPAFSAMWFGGAYISGDNDGVVQVSSSIHPRQYSRLFTRNYDHDNIRLGSVVWSSIEPSVRGTFRSKVSENSANSPVVDQATTINANSILRGGMLENASRGGIRFNLETGVKTANFDFVSNSADLDVAFVDAQGNRYAANKPVLDTEFFRGAYHYSAEVAAPASGAWSVVVSGGKADTAYLFNATLDSNLNVQLDAASLLAQPNQSLGLKVNAANAQGLSVKAQLTGTPQGTELHSALPTNRSLSAKGVDSASLNLTSPQAFGLYQVAVTVTGTAADGSSFERSIPLNIGVVDSATKNPANSLPAGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B076</accession>
    <name>RL25_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplY</name>
        <name evidence="1" type="synonym">ctc</name>
        <name type="ordered locus">Haur_2547</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B076"/>
    <dbReference type="SMR" id="A9B076"/>
    <dbReference type="STRING" id="316274.Haur_2547"/>
    <dbReference type="EnsemblBacteria" id="ABX05185">
        <property type="protein sequence ID" value="ABX05185"/>
        <property type="gene ID" value="Haur_2547"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2547"/>
    <dbReference type="eggNOG" id="COG1825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075939_2_2_0"/>
    <dbReference type="OMA" id="HVDFYEV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000214653" description="50S ribosomal protein L25">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <sequence length="199" mass="21628" checksum="009FE500BF70C7A4" modified="2008-01-15" version="1">MANETLRLALQPREITGKKVQSLRDQGILPIGICGRGIEPYSAQVDEREFNKVINQAGYSGLIELSIPGQKRQVAFLLEVQRNSVTNRIIHADLRVVDANAPVELDIHVALQGENDMVSRGNAVLNLVQSVIRVRALPGDVPHQIDIDASSLTEIGQQILVKDLSLPATVEILDDVETLILTLGYPQAEEAPAAETAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B2</accession>
    <name>A9B0B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2583"/>
    <dbReference type="EnsemblBacteria" id="ABX05221">
        <property type="protein sequence ID" value="ABX05221"/>
        <property type="gene ID" value="Haur_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2583"/>
    <dbReference type="HOGENOM" id="CLU_2479072_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2611-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="87" mass="9223" checksum="E26F8FB9FF4FD79A" modified="2008-01-15" version="1">MSDLEHLQSLVEDAFLEAPLMYANGFINGLGATDAYTVLQTNGRAVAVVNMSLPVAKTLGQGLLAMIAAYEEQTGDTVATLDQIHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0D1</accession>
    <name>A9B0D1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_2602</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="3 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2602"/>
    <dbReference type="EnsemblBacteria" id="ABX05240">
        <property type="protein sequence ID" value="ABX05240"/>
        <property type="gene ID" value="Haur_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2602"/>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_2_0"/>
    <dbReference type="OMA" id="QVPIVQK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2630-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="12">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="13">
        <location>
            <begin position="356"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX05240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="471" mass="50906" checksum="8C68D83AAB4D0025" modified="2008-01-15" version="1">MRRTKIVATLGPASDTEEKMTALALAGMNVARLNFSHGTHNDHSERIRLLRQISIKLNRPIAVLQDLQGPKIRTGKLVDKQPIPLKAGESFVITIENEVGRVGRVNTTYKNLPTDCKPGDRILLSDGLIELRVQECTKTEVITEVVTGGMLRENQGINLPGVAVSAPAMTEKDREDLIFGLHEGVDYVAISFVRRAEDVQLVKQEIAGAGYRTPVIAKIEKPEAVDNIESIVAVADGIMVARGDLGVEMPPEEVPLIQKLIIASANRAGIPVITATQMLESMIVNPRPTRAEASDVANAILDGTDAVMLSGETANGAYPVEAVTIMARIAEVTERGAPPRDAQQRNASDAPETYSHAISHAACAIAESIDIAAIVAFTSSGFTARLVARDRPRVPIIAMTHEYDVYHRLALLWGVESLLCPFVTRLDDLSNLARAIMIERQVIKPGDSVVITGGHPLAVRGTTNFLKILSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I5</accession>
    <name>A9B0I5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of SigK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sigma-K anti-sigma factor RskA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4572"/>
    <dbReference type="EnsemblBacteria" id="ABX07203">
        <property type="protein sequence ID" value="ABX07203"/>
        <property type="gene ID" value="Haur_4572"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4572"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075802_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4627-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="27886" checksum="612C778B565F364B" modified="2008-01-15" version="1">MTDQRDELIELYALGALPADEAAEVEDYLASNSQAQQRYSQYRHISQALLWSVEQRDPPAGAYERFRERMATPSNVPAKPSQQPTQRSSWLANLFGRRYRLMATALTLFLVLLGGAGGRIWQLQNEVGALQPLVEQNKQLTALLGESGTQLVPLADTGNGMAGGTINIIVNPQTGQSYLRASHLPPLTANQSYQLWLIADGTPQSMEVFGVDTSGDALIWIDRLPSTGAENLLGITVEPAGGSQQPTSNPVAVGTIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T8</accession>
    <name>A9B0T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1160"/>
    <dbReference type="EnsemblBacteria" id="ABX03808">
        <property type="protein sequence ID" value="ABX03808"/>
        <property type="gene ID" value="Haur_1160"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1160"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972454_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1182-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31285" checksum="74391C5E0EE8448F" modified="2008-01-15" version="1">MNYCIIVDDLAVDRQLAARYLQAAGYQTSMARSSKQAIEQLQQALAIYQPSQILLLVDLNMPNDPALQQVVASSLAGANLALQLQIQIANGSLPPLAIVALTALSASEVHQTAIAFGCDAVLEKPATPDLAQRIEQALATSAQQSPIGSQALLNILRLRLLAPTPSPPLNEEDLTKALLQLHRQGLVGLGTSHLAKYLFPQIANDYQRGLQTQAKIANVIREAMQLNVLETLAILEGEFVQLHAPQTQAQQLHLSKSEYYRRRKEAIAQLYHILAEARAESKEHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z7</accession>
    <name>A9B0Z7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2637"/>
    <dbReference type="EnsemblBacteria" id="ABX05275">
        <property type="protein sequence ID" value="ABX05275"/>
        <property type="gene ID" value="Haur_2637"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2637"/>
    <dbReference type="HOGENOM" id="CLU_1903819_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2665-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14896" checksum="E67E921B6DD34F77" modified="2008-01-15" version="1">MKQHWHKLTNKQAWLPIAGSLCGLILTHGIALACIVYCAVIQSDNPLIAHHGHHHHQTQIPVMIDDFQHLQPAPFTSGVLEQGHEVPLALATLLILLGSIRIARWIYRELGYLGRSWIERPLAPPPRYLGCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B121</accession>
    <name>A9B121_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2661"/>
    <dbReference type="EnsemblBacteria" id="ABX05299">
        <property type="protein sequence ID" value="ABX05299"/>
        <property type="gene ID" value="Haur_2661"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2661"/>
    <dbReference type="eggNOG" id="COG1480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015767_1_2_0"/>
    <dbReference type="OMA" id="HWFESGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2691-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07698">
        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="2">
        <location>
            <begin position="484"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="717" mass="80856" checksum="4F648B0A6CF347E4" modified="2008-01-15" version="1">MIVRSYRLKTLLRSFIEHHHHLVLVLFGAVLTLILTLIFTWRSAINQDIMVGRPSPRTINADRDLTFESPLLTEAKRREAANDPRNLVYNEDTQIHGQQREQLQATYSVINSVRENPSLNLDQQRGQLTELPSLPLSDTLAITILEADDDTWQRIKDQTNALYDRTLRENNYSIDETTLAEIKVRYLPYNLPSSLKPDQRAVVLYLVEQTLHVNRTLNQEETERRQQTARNAVQSVSKDVVNGQNIVRQGDTVSAEQYETLIKMGLITPELGFDGFMGRFLLALLVALALCTALYIDQHNLLTWPRALLVILILMVIPILSGRIFLNTWLNFPETFALAVIAIPLAALFNNNLALVISALVSIVMMFLGEGALQVGMISFAGALCGIYAIRRADRAMAFIMAGVWIALGVFATAMIWRLIQPQGVTWQQTMFTLIFSMLNGGITAMMSLTLHNVLGRIAGIVTPMQLLELAHPNQPLLRRLMQEAPGTYHHSVVVSNLAEQAAERIGADTLLTRVGAYYHDIGKMLRPFFFTDNQYDRSNVHDNLDPQTSAKLIADHVIEGAKIARQHKLPEQIVNFIVEHHGTDVIRYFYQQALQAQDSVDINDYRYPGPKPQSKETAILMLADGVEATVRSKEQAGMLVAERHDDDDQQAPKGCQSIAQVVNQSIDMRLASGQLDQCPLTQKDLNTIRQSFVKTLQGIYHPRVEYPKLMREPQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B137</accession>
    <name>A9B137_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2677"/>
    <dbReference type="EnsemblBacteria" id="ABX05315">
        <property type="protein sequence ID" value="ABX05315"/>
        <property type="gene ID" value="Haur_2677"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2677"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_20_0_0"/>
    <dbReference type="OMA" id="CTHELPA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2707-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24443" checksum="1407A3F7F4436E14" modified="2008-01-15" version="1">MPRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIVDQTLGYLGMSVTPEVHATLTKQRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAETIPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLNVDPREVVYVGDGDTQEHAGAAKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B167</accession>
    <name>A9B167_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase_C_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2707"/>
    <dbReference type="EnsemblBacteria" id="ABX05345">
        <property type="protein sequence ID" value="ABX05345"/>
        <property type="gene ID" value="Haur_2707"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2707"/>
    <dbReference type="eggNOG" id="ENOG503366P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_452541_0_0_0"/>
    <dbReference type="OMA" id="THASIEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2738-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase_C_3" evidence="3">
        <location>
            <begin position="393"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="603" mass="68055" checksum="E01E6705CBF8A6AC" modified="2008-01-15" version="1">MIRTHASIEWLASLPTSERHVLAHLWQVADAAQLGQPSAIQALVARLSTPERSALDRVIAAGGKLAAKSLEREFGKIRSHRDIVTPRAYLLALHGQASVLERLYILGLLQPLKTLDGEYYVIFSDWLQALPAVSAPSLPTWQQHPSPSNWIEADLNQTETLLTTILALCYQQPLQLTRQLQLERDGLKAICQRIAVSTPASERQFPQLAWLRNLALEAGLLHIQHQQLQLAGNPINWLEATPKQRLERLFNAWLVCDFDEFSLTELQPQTPFTLQAARQALWQVLTTAPPDQWLAFDDLLAQIQALHPELLRSDFEQPVIHNQSNDSFVGWQHWAKVEGAWIKAACQGPLFWLGLLDVDQLNHPQALRLTQWASCLLDPAHEPSQFAGQLQLSSDGLIRVPPTVEPLPRFQIQRITEWQSTDSHGTMLVRLTAHSYSQALQRGIQASQMQTFLQRWCDRPVPNDLQSLFQQWQNDRQHLLARPALLLEADDPRLLNELAKLPNLPPYAELNPQLWELEIADSAALTNLLHTAGYAINPVSEPDQRISDHDLKQLITALLTVQRLAPTVVSQAVIERVVQALPSSERQQLTANVNQWLSIINRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A7</accession>
    <name>A9B1A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4663"/>
    <dbReference type="EnsemblBacteria" id="ABX07294">
        <property type="protein sequence ID" value="ABX07294"/>
        <property type="gene ID" value="Haur_4663"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4663"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="NYEFFGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4720-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="232" mass="26275" checksum="A1988EA40CA171B3" modified="2008-01-15" version="1">MANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTGLEVCRRLQSDRRTPVIMLTAKSEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQPQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTAREFDLLYFLARHRERVFTRDQLMELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I5</accession>
    <name>A9B1I5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX03870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1222"/>
    <dbReference type="EnsemblBacteria" id="ABX03870">
        <property type="protein sequence ID" value="ABX03870"/>
        <property type="gene ID" value="Haur_1222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1222"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_756134_0_0_0"/>
    <dbReference type="OMA" id="INGDSSW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1244-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="1">
        <location>
            <begin position="56"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39808" checksum="A24C4DAC2D6F78C1" modified="2008-01-15" version="1">MSPPTSLQRGTGFHHLIADEYRLIAQVLTYCHAAGYAIPPLLVIDYVIALKTSPFVLLFGPTGQGKTELARLFAQALVHPFEDQYTYVNLGSSLQAPEIQDRFGWMKFVETLENAAAPANAGRLFFLCLDNLRPHDVYTYFANVSRDADGITRLVMRGYPPDKWPALPSNVIITGTLDAEHPVDSDQSALLAQINCVYMQPQWLQSNIRTVKRQQRMAPVGMQRLLLEQQYRSDEAATERLHALLGPHLDDILQPPSELMAILWQSSLTYTQTWRSTMLRAVANSFTIEGHGLFIPYDVLNNAQFAYSFVMARQLLLRLWGQPQHSAAIEALLHRQLAQLPSTTLVGLTDSLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T2</accession>
    <name>A9B1T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2736"/>
    <dbReference type="EnsemblBacteria" id="ABX05374">
        <property type="protein sequence ID" value="ABX05374"/>
        <property type="gene ID" value="Haur_2736"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2736"/>
    <dbReference type="HOGENOM" id="CLU_2316446_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2767-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="11482" checksum="815C9CB3B706815F" modified="2008-01-15" version="1">MRPLSKLYWTLYLRSGLGIAALLSISQFLFSPQGRKLALNIVILTIFWLIHRWVKTHQAELDNAVKPTRAQSFEQKSDAATATQLHFREVMYSQQQHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B244</accession>
    <name>A9B244_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(ADP-ribose) polymerase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4763"/>
    <dbReference type="EnsemblBacteria" id="ABX07394">
        <property type="protein sequence ID" value="ABX07394"/>
        <property type="gene ID" value="Haur_4763"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4763"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004841_2_2_0"/>
    <dbReference type="OMA" id="RAAINEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4821-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="SSF142921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARP catalytic" evidence="2">
        <location>
            <begin position="220"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="46868" checksum="19CD963692E0E936" modified="2008-01-15" version="1">MGTASDAPQGEPTQRRKFQLTNLDGNNNKYYLVEIWQLAANDVYFRATYGRVGSAAQIDEKVTTQEWIERKIREKLKKGYHEVALHRPTVVATASAPVVTLAEPIRNVIDYIFDEAGEGIASYLAVGLDAISAEQIEHGRKLLALAQLQHSTWQKSQTPANLALLSSTIQHFYNTVPTKLPSRIKRETVVENFCNDFDQQETRLHQLEAAIATMTAQQQNPQVSRYETLGAELDMLPQNDDRYRQICDYVDRTSVHGYKVRVNSIFTINIAAERRTFEQSQLGRSNTQLLFHGTAGQNVRHILRSGLVCPRTPSNGRMFGHGIYFANKATKSTNYCSVRRRNRPMFLFLADVALGNPYVAPTAQSDFRAAPKGFDSVWGKAQHTVAWAGKLQYDEFIVYQSAQQTLRYLVLFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A0</accession>
    <name>A9B2A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4820"/>
    <dbReference type="EnsemblBacteria" id="ABX07450">
        <property type="protein sequence ID" value="ABX07450"/>
        <property type="gene ID" value="Haur_4820"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4820"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OMA" id="RLRPFNH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4879-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="25"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="37413" checksum="AA5D8A3BEF245151" modified="2008-01-15" version="1">MRIGINSFLPTISTRSIVRAMTRALITGANGFVGQHLVRYLQQATTWELWALGREAHPQLPTVLADLLDRSAVATAVANAAPDLVVHLAAQSAIPQSFRDPAGTFSINVLGQLHLFEAIKSAQLDPIVLVVGSNAMYGMAHRSGLPADENTMLCPADPYAVSKAAQDLLAGQWWYSHGLKVIRARPFNHTGPGQRADFVVPAFAHQIARIEAGLQPPVIQVGNLTPQRDFSDVRDVVRAYHLLLERAQPGEIYNIGVGQSVSIQSILDRLIALSGQTITVEVDPQRLRPVDVPIVACDASRLRSQIGWEPQYCLDDTLSDILNEWRSHVATEQERVGSHINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D6</accession>
    <name>A9B2D6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03981">
        <property type="protein sequence ID" value="ABX03981"/>
        <property type="gene ID" value="Haur_1336"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1336"/>
    <dbReference type="HOGENOM" id="CLU_1600444_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1357-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18283" checksum="8018A99ADD0DCA16" modified="2008-01-15" version="1">MTATIAELQNQLLEVLPESGRTDLTTESHAAAGVQVWIERDGVGWHAYLSTPTIEHQYISSRFIERNLESLKEHAVFCADEAVLDLTPKVPAAAKPAKKTRKTKKPLCACPSCTKQSNANGVFHCLKGREYVIFAAGQCLGYRKTESAADTVLREYRYAQLTKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M7</accession>
    <name>A9B2M7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_2840</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2840"/>
    <dbReference type="EnsemblBacteria" id="ABX05478">
        <property type="protein sequence ID" value="ABX05478"/>
        <property type="gene ID" value="Haur_2840"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2840"/>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111016_3_0_0"/>
    <dbReference type="OMA" id="IGQGACY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2871-MON"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="19028" checksum="01698799D0293E58" modified="2008-01-15" version="1">MSQRIYRLQVTKDQLGFAAAHFITMRGKCERLHGHNYRVTVEVEGFLCEDQYVVDFGVLKKHAAEIARTLDHRVLLAAENPKIEYSQNEQHLTVRYEDKYYVFPIAEVIMLPIQNTTAELLATYFCAELCERLRQDGVDTLKMVGVWVSEGPGQQAFASREWVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S8</accession>
    <name>A9B2S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2891"/>
    <dbReference type="EnsemblBacteria" id="ABX05529">
        <property type="protein sequence ID" value="ABX05529"/>
        <property type="gene ID" value="Haur_2891"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2891"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2922-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="457" mass="51114" checksum="D6035C7993F222AB" modified="2008-01-15" version="1">MMTETALASPALIAPGPCGRLLIGNLHDFIDDFLVTMQRDFVNHGDIVRYQIGSRIVHVVSNPDYAQYVLVEHQRDFPKVGGNGGLQIIAGNGLISNPSPESWLIQRRMMQPMFHRKRLAAMGEKIDGAGARMIQRWQALPDAAPIDMDHEMLQVTLDIIMQTMFSADMLGEVGKLAPAVTAAVDYANYRIFNPFSLPLPMPTRRNRAYMQARKVLDSMIFGLIKQRRAATEPVGDLLDMLLEAQDAETGERMSDEQIRDEVLTIFAAGHETTANTLTFGWYLLSEHCEIRQNLQTELDQVLQGRAPSVNDLPQLPYTLQVFKEAMRLYPAAPITGPRRVTKPTQLGGYDLPLNSQVIVSITNLHLHPAFWENPLQFDPSRFAPNANQPRHHLAFMPFGAGPRKCIGNNLAEMEGALLLACVAQHYNPQLQPGHQVKPEMAITMRAKAGMPMLLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U7</accession>
    <name>A9B2U7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3374"/>
    <dbReference type="EnsemblBacteria" id="ABX06010">
        <property type="protein sequence ID" value="ABX06010"/>
        <property type="gene ID" value="Haur_3374"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3374"/>
    <dbReference type="eggNOG" id="COG1234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_0_2_0"/>
    <dbReference type="OMA" id="NPCSGYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3411-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="32"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27136" checksum="87A02FEDCCE794FA" modified="2008-01-15" version="1">MSNLIVLGSGTALPDAERENSGYVWQSAAGLVLLDCGGSPYRRMLKYGLDPRQLRAIFISHNHPDHLMGLPSLLLHLWLAQHNGELLVFGNSRTIATAEAVVQAADLGIHAIKPQFQTLDDAGGKVELPFDLGATLTTAPTYHSRPTLALRIDQTGQGSLVYGADSGPCAALVELSDHAHTLIHECTVSTPFDTHSTPEQAATTAQNAGVQRLILTHYSPINTAPEAEVLARVATIFKGEVLIAYDGAVFALDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U8</accession>
    <name>A9B2U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3375"/>
    <dbReference type="EnsemblBacteria" id="ABX06011">
        <property type="protein sequence ID" value="ABX06011"/>
        <property type="gene ID" value="Haur_3375"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3375"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2342328_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3412-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="13519" checksum="0FA7DA67657D2E45" modified="2008-01-15" version="1">MVVRLVRLKFAPEHVAEFLAFYAECEPTIRHQEGCLALSLLRETGDPTAFATWSTWESGRDLQRYRRSEFFRGFWPRVKSLLREPADAVSYDALTGDAIPDFHPQPTHGAQLTPLEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B310</accession>
    <name>A9B310_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_hydro_cc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07473">
        <property type="protein sequence ID" value="ABX07473"/>
        <property type="gene ID" value="Haur_4843"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4843"/>
    <dbReference type="eggNOG" id="COG5309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_635969_0_0_0"/>
    <dbReference type="OMA" id="FWFKYED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4903-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Unchr_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_cc" evidence="1">
        <location>
            <begin position="190"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="431" mass="48913" checksum="A12C1FCD3C9557B2" modified="2008-01-15" version="1">MLRICQRLLGFMLIIFLITQLPAMSYAEPPTDQPSDWWGIVVRDPAYEWNTNPAYPNAANQAFIDRMFDEIVAMGGHWVRFEFHGAWDGSNYGSFNLAQADYFISAAHSRGLKVLALLGTDILRGPQAGVQHFDGGTVSGSIPTSNPDRELSPCPPAPIGCGVNAYQKAWLERAISIADYYRGRIDAYEIFNEPNFYFALIGDTNGQQDEMNPYYLAQTITKLYRILRDPSRNDQTPLIVGGLHPLTSNESGRTDRGYLQALYQAAPFSNWANSHNGQYPIDGVAYHPYPAEMRRLISDNDFLPLVAPRLDSLIATMRSFDQTSQLWLTEIGTRGDPNNPSELQRQADFMRQFVATIYGRPEIANWFWFKYEDFPPASEAWGVVHINYDGNGAYDLNGTVSLYKPSFYAYRDLVDHFRQRVWIPQVLNNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B337</accession>
    <name>A9B337_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4870"/>
    <dbReference type="EnsemblBacteria" id="ABX07500">
        <property type="protein sequence ID" value="ABX07500"/>
        <property type="gene ID" value="Haur_4870"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4870"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_2_0"/>
    <dbReference type="OMA" id="MPMITLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4930-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15897" checksum="B1D2CC1655C0A7DB" modified="2008-01-15" version="1">MQIKQIESAAEIASTFAVMHELRPALVEAEYVAQIQRMIERDGYRMAAVMVDGQVQAVAGYRFMEMLYAGMLLYVDDLITSASQRSSGHGKALLDWLKAEAKAQGCNELHLDSGVHREQAHKFYFREGLTISAYHFRIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A1</accession>
    <name>A9B3A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1420"/>
    <dbReference type="EnsemblBacteria" id="ABX04064">
        <property type="protein sequence ID" value="ABX04064"/>
        <property type="gene ID" value="Haur_1420"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1420"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_0"/>
    <dbReference type="OMA" id="PFHANEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1442-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="280" mass="30377" checksum="5E4247C37C7B66B4" modified="2008-01-15" version="1">MRLLNKHVIITGGSSGIGFATAQRILARGASVSLIARNRIRLVEAAERLQPLINRAGQRIEIATADVRVRHDVSQAIADLIQRAGPCDVLIAAAGGVQAGPFQQLDDQVFRDLMDLNYFGTLHAIRAVVPHMQNRRVGSIVAISSVAGLGGTFGYSAYTPTKFAIRGLMEVLRPELKAYNITTSVVYPSDIQTEVGQASSNGDSSLSNQQPINADRIAQAIVRGILKRRFIITADAQSSWLVRVGNLAAPILNRFFDRPVKRSQQQPKPHEDNTPPTGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B6</accession>
    <name>A9B3B6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1435"/>
    <dbReference type="EnsemblBacteria" id="ABX04079">
        <property type="protein sequence ID" value="ABX04079"/>
        <property type="gene ID" value="Haur_1435"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1435"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072993_1_4_0"/>
    <dbReference type="OMA" id="NVTFTPC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1457-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="42"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14571" checksum="DB3A4645B2D514C0" modified="2008-01-15" version="1">MEIKRSGSQPSEVGSAAYFSGTVRIDPLFQASEPARVRGASVTFEPGARTAWHTHPLGQTLIITAGCGLAQRWDGPIEIIRPGDVLWFAPGEKHWHGAGPTTAMTHIAIQEQLNGTVVEWLEHVSDEQYQAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3J0</accession>
    <name>A9B3J0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease V</fullName>
            <ecNumber evidence="1">3.1.21.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Deoxyinosine 3'endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Deoxyribonuclease V</fullName>
            <shortName evidence="1">DNase V</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nfi</name>
        <name evidence="2" type="ordered locus">Haur_2924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the endonuclease V family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2924"/>
    <dbReference type="EnsemblBacteria" id="ABX05562">
        <property type="protein sequence ID" value="ABX05562"/>
        <property type="gene ID" value="Haur_2924"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2924"/>
    <dbReference type="eggNOG" id="COG1515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047631_1_1_0"/>
    <dbReference type="OMA" id="RIHFRQA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043737">
        <property type="term" value="F:deoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00801">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with target DNA" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="232" mass="25360" checksum="DD3E35FC9D8E2932" modified="2008-01-15" version="1">MSRFPNSQVHRWDLTPEQAIDLQLQLRDQVRLVDDFAQPLQTVAGVDAAFEDDGATTRAAIVILNFPALQPVEKTLVRRPTNFPYIPGLLSFREIPAVLAALEQLQQLPDVLLCDGMGIMHPRRFGIAAHLGVLTDLPTIGVGKSYLCGTHEPVPNQQGAWVPVYDAGEQIGAVVRTRVGTNPLYISPGHRVSISTAVDLVLGCTTKYRLPETTRHADQLSKDKANNGGIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A5</accession>
    <name>A9B4A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrimidine 5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0010"/>
    <dbReference type="EnsemblBacteria" id="ABX02662">
        <property type="protein sequence ID" value="ABX02662"/>
        <property type="gene ID" value="Haur_0010"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0010"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059493_2_1_0"/>
    <dbReference type="OMA" id="LYPHHVN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-10-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="24677" checksum="904827D895DCADDD" modified="2008-01-15" version="1">MTLRFALYDLDNTLYADSSGLMEQINDRIGLFFQEHLHLAGEEAQRLRQHYYEQYGTTLAGLQKHHGVVETEEYLAFIHQLTLDVLLPDDGTLHVALQALPLQKVIFTNSPREHAVRVLNRLGLHDHFAQIFDIRAFEFLAKPDFSAYHTVLTALNAQGHECVLFEDTMANLAPAKSLGMTTVLIAPADTQHPFADIIVPNVLAGTLAIHERCGVPLDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E6</accession>
    <name>A9B4E6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0051"/>
    <dbReference type="EnsemblBacteria" id="ABX02703">
        <property type="protein sequence ID" value="ABX02703"/>
        <property type="gene ID" value="Haur_0051"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0051"/>
    <dbReference type="eggNOG" id="ENOG5033G2Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143267_0_0_0"/>
    <dbReference type="OMA" id="YWFANSK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-51-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021414">
        <property type="entry name" value="DUF3054"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11255">
        <property type="entry name" value="DUF3054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15121" checksum="611C0B7A2EDB4A46" modified="2008-01-15" version="1">MTTNQELAATPSNSARVIGLIVGDVAIFALFVIIGRRSHAEGVNAMDVVNVAAPFVIGWGIAAPLLKLYTPAISDHTKTALQRTALAWCLAAPIGLTLRSVLWKHDFKPGFAITTFIFNMILLLAWRGWSAYRTGKQSR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z6</accession>
    <name>NUOC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit C</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoC</name>
        <name type="ordered locus">Haur_3081</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B4Z6"/>
    <dbReference type="SMR" id="A9B4Z6"/>
    <dbReference type="STRING" id="316274.Haur_3081"/>
    <dbReference type="EnsemblBacteria" id="ABX05719">
        <property type="protein sequence ID" value="ABX05719"/>
        <property type="gene ID" value="Haur_3081"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3081"/>
    <dbReference type="eggNOG" id="COG0852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042628_6_0_0"/>
    <dbReference type="OMA" id="KDIFRGP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000358112" description="NADH-quinone oxidoreductase subunit C">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01357"/>
        </source>
    </evidence>
    <sequence length="171" mass="19725" checksum="AAC5B11F43515F30" modified="2008-01-15" version="1">MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGVDYLGRDPRFEVVVHLTSFQNKMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGIIFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNEDWIYANKPFAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B524</accession>
    <name>A9B524_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3525"/>
    <dbReference type="EnsemblBacteria" id="ABX06161">
        <property type="protein sequence ID" value="ABX06161"/>
        <property type="gene ID" value="Haur_3525"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3525"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857305_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3562-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="28"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="37931" checksum="9DDA700272015E93" modified="2008-01-15" version="1">MDQRLREVLEYLAKQSLVEPTRWQHWQLTPIAGGANNRVYRAQSTNADYAIKWTIRDERRRAWREYQSLQIVAEFNHLLAPQAVWLDEANFAQPVVVQTWLDFPALTSIPQDSAQWQGLIAHYWALRQITQTSATFELPKATLNMTSVADGKALIEQHCAKIPTDQLPITLENLLIWLETWAVPELPSPPMSLCRVDSNWRNFLVTPTGFVSVDWENAGWGDPNFDIVDLMTHPAYAEVPTEHWSWFVQAYCGFGDDPRAVQRIEIYRTLMLIWWVVRWQRYLYEVPRGLDERLVQRPPAWLITAQANYQRYLNLAQQAINQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B555</accession>
    <name>A9B555_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3556"/>
    <dbReference type="EnsemblBacteria" id="ABX06192">
        <property type="protein sequence ID" value="ABX06192"/>
        <property type="gene ID" value="Haur_3556"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3556"/>
    <dbReference type="HOGENOM" id="CLU_982697_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3593-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="32779" checksum="B815C45FEF1FD282" modified="2008-01-15" version="1">MNPSIIHLRISRSLIVLVGLTWSLGLMFGLGFLSNYTFWAAACFTGWWLALLVRFGLLTWQHVYLSDQGIRVKNYTGDYTFAWNTLHAIEFVTEPAAPRFMDRDLSYLWATYAVRFSDAQRSIIVHTRFTEHDRTLFKTKLAHYIQHYAIPNKTIDTLDYPVIYPERLSIWQKLMRLHRPPLIKSLEILRRFCWCLLAIAMIYAAVTEQEFFVALTAFAIYQVLKLGLALLPNAIKQPDLLIKPQESALYVPKLVDKTLFARLLGFYGLIVVLISIYYGIVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A4</accession>
    <name>A9B5A4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thump_like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0077"/>
    <dbReference type="EnsemblBacteria" id="ABX02729">
        <property type="protein sequence ID" value="ABX02729"/>
        <property type="gene ID" value="Haur_0077"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0077"/>
    <dbReference type="eggNOG" id="COG2242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038123_1_1_0"/>
    <dbReference type="OMA" id="LCRADAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-78-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009452">
        <property type="term" value="P:7-methylguanosine RNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041497">
        <property type="entry name" value="Thump-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18096">
        <property type="entry name" value="Thump_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thump_like" evidence="1">
        <location>
            <begin position="320"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="43480" checksum="F7F62871CDB62F2B" modified="2008-01-15" version="1">MEMEGFRWLLSDAGQQLLAELSNDRDLNEANFLRYTTKLRKHYPAEAVTAALETNLLRRAAQAKFPQASQLYFTREALEQATPWLVASYRQRHFATGSRLVDLGCSVGGDALALAQSCSVLAIDRDPLRLAMLEANAQALGLSQQISIQEADFTTLEFAGYAGLFIDPARRSNGKRIWDVEHYQPPLSTLERWRGQVPIHGAKVAPGIPDDAVPAGYDLEFISLDGDLREACLWWQAGQVGGQRKAVVLTSAGAEHSLIADSTQAAAALSEPLAYLYEPDPAVIRAHAVADIANQLDLAQFDASIAYLTSDRLVQSPFLRAWQIEQWLPFNLKLLRQILQAREIGRVTVKKRGSPITPEELSKQLRLKGRYEQTLVLTKLQGQPVVLLVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C7</accession>
    <name>A9B5C7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0100"/>
    <dbReference type="EnsemblBacteria" id="ABX02752">
        <property type="protein sequence ID" value="ABX02752"/>
        <property type="gene ID" value="Haur_0100"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0100"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008213_6_0_0"/>
    <dbReference type="OMA" id="PAITHQT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-101-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="64"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="302"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="440" mass="48878" checksum="742B59E36D2E9628" modified="2008-01-15" version="1">MTRPATQAEQPEQEQWLLDEASLLDASLLDEPDEDLPEVDARLQGGFKAKLQFAPRPYQTEAVAAWTANEGHGVIVLPTGAGKTITAMLAIAKLGLRTLIVVPTIELLYQWRDTVVQTLALDPKLVGVVGDGQREWRPITVITYASAAMPDAPLENLGLLICDEVHHLPSPAYSTIALRSRTPYRLGLTATPERSDGSHTALDRLVGKVVYQRAPADLAEEGHIAKFREKRILVDLTADELVRYETLMTTWRWFLAKHRHKLASGGDFFGELIRRSGSDPQARNALQAQHQARMIALNAEKKLEHVGQLLSQHPNDKIIIFSEYNALVNTISRQFAIPSITYRTAADERKSILDGFRSGRYSKLVTGRVLNEGVDVPDANVAIVVSGSATAREYIQRLGRVLRKKPDEALLYELVTRNTSEVQTARRRKKAVAAHNLQAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H8</accession>
    <name>LEXA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LexA repressor</fullName>
            <ecNumber evidence="1">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lexA</name>
        <name type="ordered locus">Haur_0151</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5H8"/>
    <dbReference type="SMR" id="A9B5H8"/>
    <dbReference type="STRING" id="316274.Haur_0151"/>
    <dbReference type="MEROPS" id="S24.001"/>
    <dbReference type="EnsemblBacteria" id="ABX02803">
        <property type="protein sequence ID" value="ABX02803"/>
        <property type="gene ID" value="Haur_0151"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0151"/>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_45_2_0"/>
    <dbReference type="OMA" id="HVWLLPH"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000089569" description="LexA repressor">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="1">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="1">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <sequence length="214" mass="23653" checksum="9C6A4B188CB92E14" modified="2008-01-15" version="1">MSGLSQRQQRIYDYIKQFIRTNGYAPAIRDIQRELSISSTSVVAYNLRALESKGHIRREGNISRAIELINAEQPLPTVLGGQRVPVLGVIAAGQPIPVPNDSANSDDSVLVPEEIVGNDKLGDVYALRVKGYSMVDALIADGDIVLLRYQATAENGEMVAARIRDENEVTLKRIYWEGDRVRLQPANVTMEAMYYPSTNVEVQGRVVGVIRNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J3</accession>
    <name>A9B5J3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0166"/>
    <dbReference type="EnsemblBacteria" id="ABX02818">
        <property type="protein sequence ID" value="ABX02818"/>
        <property type="gene ID" value="Haur_0166"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0166"/>
    <dbReference type="eggNOG" id="ENOG50307CD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1784219_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-169-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045990">
        <property type="entry name" value="DUF5946"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19371">
        <property type="entry name" value="DUF5946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="16211" checksum="023CC3EDC9845054" modified="2008-01-15" version="1">MPTTEFCLECGAPLVEGFNCWEQLGALIAWEYNDPALHAQHFLIVASYNLQHPAQFTDMAIEQLRSAFNDYLDHGVSAATLRQRAAKTYAGATRVLRPEAERRPQLQQWAMTIADVYLPEQPAGAVERLLRWASVIQANQAVAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P2</accession>
    <name>A9B5P2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1632"/>
    <dbReference type="EnsemblBacteria" id="ABX04275">
        <property type="protein sequence ID" value="ABX04275"/>
        <property type="gene ID" value="Haur_1632"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1632"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_2_0_0"/>
    <dbReference type="OMA" id="WKHGIET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1656-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="131"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="229" mass="25642" checksum="E62775E9CE3D8D8A" modified="2008-01-15" version="1">MGVSHRHIFDEQLTELHDGVFRVGTMVEAALSEALQSIKLYDQAAVRKVVQNDQTINHEVQRLHDQALLIIATQQPLARDLRLVSVVLSLLPELERMGDYAATICKLQERIAATPNFVSVSAMPQPIPRLISELGQRTSEILHAGLEALRQNDRSFADRVTELDDVIDHLYREMFEATVKVSTTSPDMAAATIHLLTLAHNLERLGDRVTNLAEQIEYLITGKVVVLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R3</accession>
    <name>A9B5R3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1653"/>
    <dbReference type="EnsemblBacteria" id="ABX04296">
        <property type="protein sequence ID" value="ABX04296"/>
        <property type="gene ID" value="Haur_1653"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1653"/>
    <dbReference type="HOGENOM" id="CLU_972455_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1677-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="30833" checksum="FB08C213024D2990" modified="2008-01-15" version="1">MHTIILTGDSEASIHCLKTISSSYTVKPLSPTTGAVHIGEYRLTTTTSIRLLAVPKDLYEELGSGLMERAIATITFVDGCQPSVDSGYFVNELEEQAFRLGKPLIVAATRGNAPNALSSEALREALGTSSYATVASCELQQISTLYRLIGQAIKLAPSTAQRHAQLQQVLNQLVNVSQYRLRGIALATHEGLTCALSFTKSSTHQRISGLSKALLDVYRQMGYACELGWASALILHADEGTLIVETLGEYLVTMLCDDDLGDIDALRRDLSAALMPQPAEPQLHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W2</accession>
    <name>A9B5W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3117"/>
    <dbReference type="EnsemblBacteria" id="ABX05755">
        <property type="protein sequence ID" value="ABX05755"/>
        <property type="gene ID" value="Haur_3117"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3117"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_368705_0_0_0"/>
    <dbReference type="OMA" id="DWRILVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3149-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="627"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="760" mass="82591" checksum="772FE7DAF75CE392" modified="2008-01-15" version="1">MRNQALTITRRDLRDTLSDWRTLIPLCILSVLLPLILRAGVAQAVSFLDDEFINRSLVPLGLLIAGFLPASLSLIGPLESFVGERERSTLESLLAMPMSDRGLYLAKFLAALLPPIGSSAVAMLMYSLAIELGRPVRVAFVQKLLSDYLTSGWIIGITCILLIKVFTMVAAAVYVSSHTTSIRAANLLASFILIPMAILVQIEALIIINGMFLPIVLINGLLLVVGLTMVGWGMYSFNREELLSREHESISKRASTQRLSQSTRTYGPVMTIVQREAVDTLSDWRILVPIGLLTFLVPIGALFGVIYAFANVDDPTGVVNLLPFIVLLVGFLPASFSLIVALEVFVGERERGSLESLFSMPISDGQLYRGKLLAAIVPPIGASLVGMLLFGVGLSVFAPTALLGRINLSIFSQMVLLSIAQALTMVSAAVVISSHTNTVRLANLLASFILIPVAIMVQLEAVLIIGERFDVLNAIMAVMLILTIVLTRTGIGSFKRESILSREHLALNFSQINRAFKAFFSEIRPAGSNPDSHLGLFNVETTNGPQRNLGLWLKRFYRQELAVVWRETRLALVVVLLFCGAAILFGSQFNPVSSREQSLANVMTRLDVGQGTLWEPPLSFIVISNSFAIFFAGLFSSITLGFFGLILPAINLMGLSFRTSSLAASGGLATALNYLVGYELPHGLLEIPLSIFAAALALRMGAALAFVPPTYSAGRHLLWAWAMYLKVFCLLIVPGLVLAGLIEVLVTPAVHQMVYGFLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X5</accession>
    <name>A9B5X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3131"/>
    <dbReference type="EnsemblBacteria" id="ABX05768">
        <property type="protein sequence ID" value="ABX05768"/>
        <property type="gene ID" value="Haur_3131"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3131"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_457693_0_0_0"/>
    <dbReference type="OMA" id="DPAWYFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3163-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="596" mass="66123" checksum="9083CC62B86DCB45" modified="2008-01-15" version="1">MQRFRQSSIILLLTMALLGLGSLLIAQWLRPDRSPRIWTGGNILANADWQSAADNGIPDGWSGNGIKRADTTNGYVLDDQYSLQLYGVNSFARSPRLTAQAGQRYRLGFQALIDPGTQRSSLGAQIQVWVHWVDTAGDDIRLDKQAPVLLGFDSQGAATWTPVLVETEPSPNQAAWLAISIHALSDDPIYLDNLSMAAAGIYIEPYPQGAIAAVSFSVDWETAMGGAIHSLSLSTDAISSATTLGLQARQGTYNLLDLFAPHHIRGTWFGNGYNFLFGNQERRTWMDDPTFAWAASTPRRWQTIDWSQTPWFSHDPYGTVESDPAWYFGDLLEPLRNAQQTIESHTFSHMYIGFAHAKELASDSNEWQAVTSSQGIAPASSLAFPYGGSDGMTEAHWQTLQAAGIRTVVRTRVLDATNVQRGVNDRHLLIDRRWWQPRQLPGHDLVALPDVYLTPQTAMTATNYLQQAIASGGVIDIYAHNYEIYNPEQIGVWQTAIQQAVEAQAWIATVPEIADRWRARQTLQLTIEQTPDQLRLQLANPSRFDLAQLSLRLPAESTGSDKGNFDQANHRLILDLPANSAEEITIWLKPSTPHVP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B660</accession>
    <name>SYA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="1">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">alaS</name>
        <name type="ordered locus">Haur_3635</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B660"/>
    <dbReference type="SMR" id="A9B660"/>
    <dbReference type="STRING" id="316274.Haur_3635"/>
    <dbReference type="PRIDE" id="A9B660"/>
    <dbReference type="EnsemblBacteria" id="ABX06271">
        <property type="protein sequence ID" value="ABX06271"/>
        <property type="gene ID" value="Haur_3635"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3635"/>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_1_1_0"/>
    <dbReference type="OMA" id="YHHTMFE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000347636" description="Alanine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="683"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <sequence length="889" mass="97075" checksum="C8BFC3596265D5EF" modified="2008-01-15" version="1">MKGSELRQRFLDYFARQGHAVVPSSSLIPADNPTLLFTVAGMVQFNDVFLGRESRPYSRAVSSQKCLRISGKQNDLENVGPSPRHHTFFEMLGNFSFGDYFKKDAIRFAWEFLTQEIGLDPKRMWVSIYEGDEQIPADEEAHDLWLAYMPAERILRFDAKDNLWSAGDVGPRGPCSEIHYYIGDDPDNQVPEGVNSEDDTYMEIWNLVFMQYNRDENGVLTLLPKPSIDTGMSLERLAIVKQGVFRSYETDLFTPIIHTVMELLGTGSDHYQANSSAYHVVADHSRSIAFMIADGLRPGNEGRSYVLRRLVRRAAYFGQTIGFKAPFLAETIATVIDMMGAAYPELRSKQAYIAEVVTGEEERFNKTLAGGLRQLEAMLPNQADKAVFSGADAFKLYDTYGFPLDLTERIVAERGLTVDLAGYEAELEAQRARGRGAAQFKKGAVTERWAERNLAPTSFTGYNELESWGHVLALEFDGEELGTVQRGQEVAFVLDRTPCYAESGGQMGDSGVLVGPHGTIVIDDVQKPVPGVFVHRGKVSKGSVSLGEQVTVTVDAARRRDIVRNHTATHLLHRALRDTLGDHAEQKGSLVAPERLRFDFNNQKGLSSEQLQQIEDQVNAWIRADSKVEAAEMALPQARELGAMALFGEKYGDVVRVVTVGCGNASDHIHTNSEAPVCSRELCGGVHVARTGEIGFFKIVSEGSVASGVRRIEAVTGRAAAEWVSQQAQLIRTLGDKLGAQPGKVEEKLDALLLDQKARRDEIERLRGEIAAGQVDSLLAQKIEQAGTPLVVARVEASDADSFRRLGEQLRDKIGSGVVILGTVIDGKPLLLAAATADQVKAGRHAGNLVKALAAKVGGGGGGRADFAQAGGRDAAALDQALAEANGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B682</accession>
    <name>A9B682_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3657"/>
    <dbReference type="EnsemblBacteria" id="ABX06293">
        <property type="protein sequence ID" value="ABX06293"/>
        <property type="gene ID" value="Haur_3657"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3657"/>
    <dbReference type="HOGENOM" id="CLU_2246249_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3696-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="104" mass="11972" checksum="663787C83974D984" modified="2008-01-15" version="1">MQCPECTAPITTTAGNCDNCGFVINQQALQVVVAPLGSRPLTAKQAWQFFLVGLVPWSIMLIFCWWFFSSYGWLYWLLMAIFGVYLVAKIGRLIFDLWRSKREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6A1</accession>
    <name>A9B6A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06312">
        <property type="protein sequence ID" value="ABX06312"/>
        <property type="gene ID" value="Haur_3676"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3676"/>
    <dbReference type="HOGENOM" id="CLU_908436_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3715-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="33551" checksum="8512801145342BE9" modified="2008-01-15" version="1">MTNQSELEHALAELETSELGQQLIGQSQRFSPSPATIQRIQAGLQPPVKRGNFMQTLFKQRPVRVLALVACSLAVALGLVFGLNQPTRSVSAAELIQRAETFASQPIVANGKARHIAIDISTTRSDGQIGEHYRDEIWLVQGQSHILLYQPARQSLNGQPVGYQMGPTIVDENYFWNYNAHDNTSVKAPFDECSLSLEQWVGSVAFGSDSDFPNATIIGTEELDGRQLTIVDLGSAVGTAWIDANTGQIWKFTSSQTYEGLTTETLVQFVVDETVELEALPAEWQTYTAPAGSPIIEQTTPYCIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H2</accession>
    <name>A9B6H2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0223"/>
    <dbReference type="EnsemblBacteria" id="ABX02875">
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        <property type="gene ID" value="Haur_0223"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0223"/>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_1381975_0_0_0"/>
    <dbReference type="OMA" id="PFYYQHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-226-MON"/>
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    <dbReference type="GO" id="GO:0016021">
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02875.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="19825" checksum="C8E087243D047A2D" modified="2008-01-15" version="1">MPSPYYDQGRRDAENGTLNQLFYHTYHDYKRGYDEIVNGPPKPKPNFLFFLIPALLLVGLAGGWFLRDRGVLSTPPTPLVVMVTVTPVTASPTFPPFAIATPAPPTPTQLVIEIGGEAITLEQVRIRPDPSIQGEPIGALDPGELITIIDGPRQGDDYTWWLIESAIGQGWVAEDFIQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="316274.Haur_0227"/>
    <dbReference type="EnsemblBacteria" id="ABX02879">
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        <property type="gene ID" value="Haur_0227"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0227"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_054358_0_0_0"/>
    <dbReference type="OMA" id="GHWLWSA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-230-MON"/>
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        <property type="match status" value="1"/>
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            <end position="58"/>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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            <dbReference type="EMBL" id="ABX02879.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="32966" checksum="515056145EE6CAF5" modified="2008-01-15" version="1">MRALLLGLLASLFFASTFVLNRLMELAGGHWLWSASLRYLFMLVPLLAIVVWRGKLGLVLQELRQQPWQWLCWSTIGFGLFYAPLCFAAKYAPAWLVASTWQITIIAGALVAPLLQTKAAPSQPAWHWRSLAISSLILLGVAVIQLQHAAAIGWREVLLGFVPVVIAAFAYPLGNRAMMQLCGQRLATFERVLGMTIASLPFWLILAGVAATTVGWPSTSQIFQSLLVALLAGVIATVLFFKATDLAQHHQGQLAAVEATQAGEVVFALVGEIVLLHSPAPTALTLAGLGVIILGMILHSWFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6M8</accession>
    <name>A9B6M8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
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    <organism evidence="9 10">
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            <taxon>Bacteria</taxon>
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    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <subcellularLocation>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX04337">
        <property type="protein sequence ID" value="ABX04337"/>
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1694"/>
    <dbReference type="eggNOG" id="COG0701">
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-1718-MON"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="DUF318"/>
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    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04337.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="37991" checksum="1D6FF8E5E7825E59" modified="2008-01-15" version="1">MAVVSIDVKPKNQRKWLLFFAPIIGILGLWLASGWLVPSNLAPLTNKLQGLVTTFQGIFIEALPFLSAGVIVSVLIGEFVKPQHLASFVPQNAFGASIFGSLLGLLFPVCECGAIPTSRRLLRKGAPASMGIAFALAAPVVNPIVLISTSIAFGDVRWALARVGFTIIIALTIGLIIGAGIKREAILTPLALTPDVEHDHSHCDHDHGACDHTHEQPKGRLAGLIAHGSVEFFEMAQYLVMGSLLAATMQTFIPQSALLTLNDSGIGFFAPLLGIVVLMLVAVLLSVCSTVDAFLALSFLGLFHPGAVMAFLVFGPMIDIKSTLMLTTTFRRSAVMAMVVLAALFAIIAGLISYVVLI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S7</accession>
    <name>PYRG_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CTP synthase</fullName>
            <ecNumber evidence="1">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="1">CTP synthetase</shortName>
            <shortName evidence="1">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrG</name>
        <name type="ordered locus">Haur_1743</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTP synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B6S7"/>
    <dbReference type="SMR" id="A9B6S7"/>
    <dbReference type="STRING" id="316274.Haur_1743"/>
    <dbReference type="EnsemblBacteria" id="ABX04386">
        <property type="protein sequence ID" value="ABX04386"/>
        <property type="gene ID" value="Haur_1743"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1743"/>
    <dbReference type="eggNOG" id="COG0504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011675_5_0_0"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000139471" description="CTP synthase">
        <location>
            <begin position="1"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-1" evidence="1">
        <location>
            <begin position="292"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="1">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="382"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <sequence length="534" mass="59136" checksum="12E2685D02C62156" modified="2008-01-15" version="1">MTKYIFVTGGVASSVGKGITVASLGRLLKSRGISVSIQKLDPYINVDPGTMSPYQHGEVFVTEDGAETDLDLGHYERFIDENLSRVNNITTGQIYSSVIQKERRGDFLGGTIQVIPHITNEIKSRVALVAKNTNADVVIVEIGGTVGDIESLPFLEAIRQMKKDVGRDNVMYIHVTLLPYLQASGELKTKPTQHSIAELRRVGISPAVVLCRSDLPVDDDMREKIALFADLPNEAVVALPTVDSIYEVPLVLEEAGLGDLIIERLALAAQPVQLDEWRSLVARIKQPKRHTTVAIVGKYVELRDAYMSVAESVRHAGWAQDIQVDIKWVSSEELEVADPVTMLGDVQGIIVPGGFGYRGVEGKIRAVRYARENKIPFLGLCLGMQCATIEFARFALNAPDANSTEFNPNTKLPVIDFMPDQLDISDKGGTMRLGVYPCILAPDTKAAKAYGRELALERHRHRFEFNNKYRKAMEAAGFVISGHSPDGRLVEIVELRDHPWFVASQFHPEFKSRPNNPHPLFRDFVQAALEQIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T8</accession>
    <name>A9B6T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase beta domain protein region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1754"/>
    <dbReference type="EnsemblBacteria" id="ABX04397">
        <property type="protein sequence ID" value="ABX04397"/>
        <property type="gene ID" value="Haur_1754"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1754"/>
    <dbReference type="eggNOG" id="COG1708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069366_1_0_0"/>
    <dbReference type="OMA" id="WGGGVFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1782-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30127" checksum="D68EF9C6A0758B56" modified="2008-01-15" version="1">MPSDIINMVVERLRTVAGVEALVLGGSRARGNHHTGSDIDIGMYYRRDLDIAALQHHAQALDDLQRQQLVTELGGWGPWINGGGWLTIHAMPVDWLYRDLNKVEHVVAACLAGEVTIDYQPGHPHGFVSSIYAAEVALCQPLYDPQASVASLKQQLASYPPALQQAFLGRFWEADFALANARKALRRGDLAYITGCCFRAVMVLTQTIFALNQHYWMNEKGAVALASGFRHVPANFEQRVTQLFSLLQPQPESIDQALQVLEALIQATAALLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6V4</accession>
    <name>A9B6V4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zeta-phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 4">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3185"/>
    <dbReference type="EnsemblBacteria" id="ABX05822">
        <property type="protein sequence ID" value="ABX05822"/>
        <property type="gene ID" value="Haur_3185"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3185"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_0"/>
    <dbReference type="OMA" id="INYPKGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3220-MON"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008150">
        <property type="entry name" value="Phytoene_DH_bac_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00982">
        <property type="entry name" value="PHYTOENE_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="55566" checksum="0550C7268CB9FAF8" modified="2008-01-15" version="1">MRIVVIGSGFGGLGAAIRLQAKGHDVTILEKRDKPGGRAYVYEQDGFKFDGGPTVITAPFMIDDLFTLAGRKTEDYVTMMPVSPFYRIFFHDQSHFDYSDDLPSMVRQIREWNPADVDGYLEFVRRAEQIFNKGFTELADQPFLKLADMLKIVPDMIKLESYRTVYGFVSKFVQDERLRQVLSFHPLLVGGNPFQTTSIYTLINFLERKWGVWFAKGGTGALVQALVKLFEDLGGKIELNRDVAEISTYNGKATGVRLRDGSEIKADAVVCNSEVAWAYQNLLPSSMRKKYTDRKLARMRYSMSLVVIYFGTDRQYRGQDGPKLAHHDIILGPRYQPLLDDIFTKKQLADDFSLYLHMPTLTDPSLAPEGCEAFYVLSPVPHLGSGTDWRQTAKPYRDRIMNFLEDRYLPNLSKHIVSEHMITPLHFAETLNSYQGSAFSVEPILTQSAWFRPHNRSEEIPNLYFVGAGTHPGAGLPGVLSSAKIVDDLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6W4</accession>
    <name>A9B6W4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3195"/>
    <dbReference type="EnsemblBacteria" id="ABX05832">
        <property type="protein sequence ID" value="ABX05832"/>
        <property type="gene ID" value="Haur_3195"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3195"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170329_3_0_0"/>
    <dbReference type="OMA" id="ETHIAFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3230-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="9781" checksum="FE028DF24DD3C4CF" modified="2008-01-15" version="1">MITAFVHIQTEPSAANGVAAGLTAIEGVAEVYSVTGEWDIIAIVRLADYDQLAKTVPDQIGSLKGIVRTSTVLAFRSFTKEEIAATWDIGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X6</accession>
    <name>A9B6X6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3207"/>
    <dbReference type="EnsemblBacteria" id="ABX05844">
        <property type="protein sequence ID" value="ABX05844"/>
        <property type="gene ID" value="Haur_3207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3207"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_5_0"/>
    <dbReference type="OMA" id="YNDTAHL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3242-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="26065" checksum="1DFFBEBCDB0A578C" modified="2008-01-15" version="1">MAKLYLIRHGQAVVNVEPIIGGIKGDRGLTALGIQQAESLRDRLMATREIVPDLFICSTMPRAMQTAEIIAPAFAQPLLYDEGFCEFNVGEADGLSWKEYNARYGKFDFDLRKPLSPGGETWQTFCQRTHSNFERVLNANPEATIVIVCHGWVIESSLSYFWPHTRSEQPNVDLEVTNTSLTHWYQHQRGGQVRWFLGGYNDAVHLHAAVRWQLEGDLEGEDHPAAPLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B774</accession>
    <name>A9B774_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06357">
        <property type="protein sequence ID" value="ABX06357"/>
        <property type="gene ID" value="Haur_3721"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3721"/>
    <dbReference type="HOGENOM" id="CLU_2012101_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3763-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="13561" checksum="1230CDA822172DA1" modified="2008-01-15" version="1">MSMNCVAVTTHLLGLGNELRTAPSLIPLPTGQISARQLLQEHVHHELSQSQQANIPSIALNYLIAKPTPNTMIAAEHVRSQAEAAFRAGDCWLMLDGVAVHNLDTPLQLQPQSRVGFMRLYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B776</accession>
    <name>A9B776_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase class A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3723"/>
    <dbReference type="EnsemblBacteria" id="ABX06359">
        <property type="protein sequence ID" value="ABX06359"/>
        <property type="gene ID" value="Haur_3723"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3723"/>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1088916_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3765-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27931" checksum="80DB9E4D6A4E4EF0" modified="2008-01-15" version="1">MQSIDRLMMSFAGQWSVDFRSCTGAIYYQYQPSLQLPSASLIKLFLAWQWYTTNQPGFDVLISEQLIVDLDGSLAQAIGSKFSSDHMIYLMLNQSENNATNVLLAQLGGIQAANSWLQQAGYQATRWGRVMLDFQARQQGLENYTSAEELTRLLHTMTDAIAKGGSMASTLVKSLVNSASDDKIAASLPPAVVCAHKSGELADVEHDAALIYSAGMWDSLVIMAAAVPDPTTARQQIRQLTSELWPNKKPVPPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B2</accession>
    <name>A9B7B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_3759</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3759"/>
    <dbReference type="EnsemblBacteria" id="ABX06395">
        <property type="protein sequence ID" value="ABX06395"/>
        <property type="gene ID" value="Haur_3759"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3759"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_3_0"/>
    <dbReference type="OMA" id="WAIIFNP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3801-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX06395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="458" mass="51637" checksum="1F7A5A661DCB8AA4" modified="2008-01-15" version="1">MDALILARWQFAVTTVYHFLFVPLTIGLSFFVALLQTIYYRTGDITYKRMTKFWGHLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAIEALMAFFIESTFLGIWIFGWDRIPKLAHLASIWLVAIATMLSSLWILIANSFMHQPVGYVLRNGRAEMADFWALLTNGHVWVQWPHTVTAAMVTAAFFVLGISAWQLRKQPKPADRLIFQRSFKLALGYALVSTILVMVVGHNQAQYMIKVQPMKMAAAEALWETADPAPMSLFTVADVPEQRDRFVVKVPGLLSFLAYNRFDGEVKGIKDLQAEFEQTYGPGNYTPDVFMTYWMFRIMVGSGMAMFGLAIIGLFFVLRKRLNFPNWYLWFMTLALSLPYIANASGWIFTEMGRQPWIVYGLLRTSDGVSTAVSGGSVLTSLIGFSLIYLVLIGVMVFLIVREANHIPDASPATVEADLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E8</accession>
    <name>A9B7E8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0269"/>
    <dbReference type="EnsemblBacteria" id="ABX02921">
        <property type="protein sequence ID" value="ABX02921"/>
        <property type="gene ID" value="Haur_0269"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0269"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-272-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="31"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="729" mass="80792" checksum="F4C506B3C5A4293D" modified="2008-01-15" version="1">MQRIGFPTFTTPLIGRDADVAALVTRLRQSPTRFTTLLGPSGTGKTRLSIQIADRLHAEFRDGVAFISLATLDDPDLVIPTIARTFGLAERGSLVYEEALVQFLRERQYLIVLDNMEQVIEAAPHVIGLLSQTEHVRVLVTSQQAANDPQEEVIPIPPLAIPLGGGSVQIETISMSPAVALFLDRIRRVRPEFMLDPNNALHIVEICRRLRGLPLAIELVAAHSDKLRPADLLLLLRNYLPAEQNVGAAPAPEQVLHPVLDWCISYSIPAIRWLLPRLGVFQGEWTLNQVQLLANEAPNTIDIAKTLEAMVAKGLLLSNAASEEPTYSMLDTIRQYAARQLKRNAQLDHACHELHAKAFQQLAIDIDTGIRQGQGMVWSKCLNQAMPNVRSALQWLYQQQRYSEIARLISSMVLPLFQQGYIREGLSWIARIGAHAASFEPEIQLHFGYANGLLSYAISDYPSALQAYGAALTHAKTLGDLDYQARLLNNQGMIYAEQTNYEAARQAYEAALTIRQQQSNVWGEAIILNNLGSVTQFQAEHQAAREYFQASLAIYQQMGDQMSQAVSFQNIAGTHLNMHEYAEAEHLYRESIAIHRQNEESPPLIMALYGLGLALLRQNADERRESGEVLHQAVTMAARLNVQRSLAIAFEGFAEWLATSNPEHAAYLVGGAASLRNACDVGYSAVSWRDITSLREQLDRNLGQAERQAAEATGEALSQAELLLLVSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7H2</accession>
    <name>A9B7H2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 8 (cellulase D) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0293"/>
    <dbReference type="CAZy" id="GH8">
        <property type="family name" value="Glycoside Hydrolase Family 8"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02945">
        <property type="protein sequence ID" value="ABX02945"/>
        <property type="gene ID" value="Haur_0293"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0293"/>
    <dbReference type="eggNOG" id="COG3405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_448181_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-296-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002037">
        <property type="entry name" value="Glyco_hydro_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01270">
        <property type="entry name" value="Glyco_hydro_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00735">
        <property type="entry name" value="GLHYDRLASE8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732580" evidence="3">
        <location>
            <begin position="31"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="511" mass="55252" checksum="81A9CA8DB32DDEE1" modified="2008-01-15" version="1">MKQALHSRWLILVMLVGLGLSLPRQQSASANPQAFSFPYNQASGINYNVTDLTQAWNEWKSAQITSNNAGGGGRLRVLGGVSNSTTVSEGQGYGLLFASLFDDQATFDGLWLFTRDYFTSRGLMHWHIGNPGQINGSGAATDGDEDIAMGLVNACIKVQQGVWPASSNGLNYCTLASTMINNIYTYEVDHAGSNPPAGLPNNQGNELLPGDSWSTATEYTQGIVNLSYFSPGYSTVFGKFTNKNTEWAAVNTRNYAITNLVQAKAGNCSKLVPNWNQYDGDVQYVSWQPEESAWWSYDAARFAWRIAIDKAWYNTSNSRETMNEIGGFFSSVGIDNIQARYRLDGTSVDNYRGVFFVANAAAAIWAAPAPQAVNCGAATASLKTTPQQAYNAVLATKDTPNSYYPNAWRLLSMLLLTGNFPNLYEMAQSGTGGTATPTITPTITRTPTATATRTATATPSNTPTRTSTGTPATITITPSRTPTATITPSRTPTVVPNLNFRMYLPFAKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S4</accession>
    <name>A9B7S4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1809</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1809"/>
    <dbReference type="EnsemblBacteria" id="ABX04452">
        <property type="protein sequence ID" value="ABX04452"/>
        <property type="gene ID" value="Haur_1809"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1809"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="FHIDAEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1837-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="274" mass="28986" checksum="4385E7CFD67ED6F4" modified="2008-01-15" version="1">MSVSPPAALQTQNLVLGYQRTTIIDQLNASIPHGQVTAIIGPNGCGKSTLLAGLAKLHPAKQGQILLDGQDIARLSPREMAQALALLPQDGVAPDGMTVADLVRFGRHPHTGLLRQWSKEDQQAVVTAIATADLMAMADRPLTTLSGGQRQRAWIAMALAQSTPLLLLDEPTAALDLGHQIEVFELIRQLAAEGKTVVMVVHDLASACRYADHLIAMCAGSIIAAGAPNAVVTPELIHQLYGVHCRLIPDPISGTPIIVGVQKSQKSEGKNQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T6</accession>
    <name>A9B7T6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04464">
        <property type="protein sequence ID" value="ABX04464"/>
        <property type="gene ID" value="Haur_1821"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1821"/>
    <dbReference type="HOGENOM" id="CLU_1439275_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1849-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="173" mass="19159" checksum="56B1650712BE5239" modified="2008-01-15" version="1">MQQKRLSWNWVGAGLAGVLLLTGCGSPQKISYAAGNSITSNTNISGYNFLDWQAGMRVLMVYDGAYQKEDCESSMELKGTTAINQCRIVFNDGTIVVWRIVTDDGKSAELIINETSYRIPEAGNLVVIHPENGVIQVQQQQRELTTISFTEKSIDAWLKADPLIAPIVFPKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B840</accession>
    <name>A9B840_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3337</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05973">
        <property type="protein sequence ID" value="ABX05973"/>
        <property type="gene ID" value="Haur_3337"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3337"/>
    <dbReference type="HOGENOM" id="CLU_745503_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3374-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735525" evidence="3">
        <location>
            <begin position="20"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="371" mass="40439" checksum="096136AA27963BAD" modified="2008-01-15" version="1">MRYWLLLLGLVLLSGCVSQQQQTEFNADASGVYEIRLGFSQQFLDFAEMGGSGASTDVLDDALSELGSIADLLPAEWQASNENWTSEDGQYRGTLIRMQFRDLAMLKDQLTSSELNELYSLVRFEDVAIEQNGNEVQLKATVKNGENSMLGSTESGELFGSGLVASPTTSWTIRFPEAISSWNEREIATLNEQQTSITYDFPYPLSRDYQLEIVGTLSAGVPQWALWGVGGLVGVGLILVGIGFILSRRKTNTQPYDLVPAGPSNGEPAYQPGSQTTPLATPSYQPKPESYQPNDQVAAYQPKPESYQPSDSISPYVPKPASYQATITSAQASNSYEQPTAFGSAPTEFGGRTPTRSLGSWQDSNDDAQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B895</accession>
    <name>A9B895_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3812"/>
    <dbReference type="EnsemblBacteria" id="ABX06448">
        <property type="protein sequence ID" value="ABX06448"/>
        <property type="gene ID" value="Haur_3812"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3812"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048401_0_0_0"/>
    <dbReference type="OMA" id="IGYVHIW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3854-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732613" evidence="2">
        <location>
            <begin position="25"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="146"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="444" mass="48238" checksum="CF791BEE382C2685" modified="2008-01-15" version="1">MRYRWLLLLGIGLLASCTAQLPWAATPTVPPTTAPLALATPTFLPSPTAQPSLEPTPTVELAQATPTATTPMSPAERLALFNDVWQTVNEHYLYPDFNGVDWAAVRAEIEPQVQAAPDDETLYTILEGMVAKLDDQHSRFARPVEAVYEDAVASGTDSYVGIGVLTIHEENAAFITLVFPDSPAQAAGLMRGDRITAVEGQPFTNADQIRGPEGSQVRLTIQTPQADPRELLITRRAVVGKITPSGRRLPNAPTVGYLLIPSLWADDMHTQVVSELSKLVADPQPLDGLILDLRSNGGGWRSVLEGILGQFVSGEVGNFYSQEKLYPLTVKPGLLYEQLKQVPLAVLIDKDSASYAEVLAGTLQFNGALVLGQASQGNTETIFQYNFEDGSRLWVAQEGFKLPDGSNFETKGVQPNIVVEDDWTQYTIPNDPAVLQAIVSFSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I8</accession>
    <name>A9B8I8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07652">
        <property type="protein sequence ID" value="ABX07652"/>
        <property type="gene ID" value="Haur_5022"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5022"/>
    <dbReference type="HOGENOM" id="CLU_082394_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5085-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030985">
        <property type="entry name" value="PpiC-rel_mature"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04500">
        <property type="entry name" value="PpiC_rel_mature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="29698" checksum="F91E739A8B39EBDD" modified="2008-01-15" version="1">MVRVNAITLYVGDVLTYLDSIWNHAPVLERLIAKGLIDDAIRRDSIELSATELQEAMDGFRRARGLLTATATEAWLTAKGLSYQRFEQLVEREAQLARLKDRVIASRMADWFTAELAGFDQVRLMILSFADVEHAQEIWRTAIQDPDRLAYQAEEAWTRGVLNETIGVFQTWLRHERPTWLPETAFGCPAGTILPLQPLPDGGIALIKVLSYQHAQRDQATQHAFRQKLFTAWLDEQRAQATITWNWGTHELQSQTPTVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J9</accession>
    <name>A9B8J9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS204/IS1001/IS1096/IS1165 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07663">
        <property type="protein sequence ID" value="ABX07663"/>
        <property type="gene ID" value="Haur_5033"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5033"/>
    <dbReference type="HOGENOM" id="CLU_029608_5_1_0"/>
    <dbReference type="OMA" id="CERQTFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5096-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="2">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="161"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="454"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="570" mass="64356" checksum="CE7EBA9A298CFB5D" modified="2008-01-15" version="1">MEVLWILQRCCFLMRLSCRSMTGRWIRPISRSPFAHTTPRTLPCPICSTPAVRVHSRYVRTLTDLPWATYTIKLSLRVRKFFCDLPTCNRRIFTERIPTILQPSARVTLRCTHAQRHVGLATGGVGGAQLTTLLRFAAGRDRLLRIVRQMPLPAIGKPIHIGVDDWAWRKGQRYGTIIVDLDTHRPLAVLPDRQASTLTTWLHAHPSVAIISRDRSSAFAEGAAAGAPHAIQVADRFHLMVNVREALLQTLVAHRTLVEAVLSQPTPLTAAPHPDAQRTLMVDDPLPPQPIPAQVRHRSDAIHARRQRQFEQIQELVARGWTHRAIAHELGLTRQTVARYHAIHDGPPPQHHAHRRSVLDRFKPYLIERWNTGCLNAAQLCLEIQAQGYQGTAHTVRRYVTQLRKASGLPAWSRDGAARRGHVGQAWPCGSLTQLVWELVRQPTKQAAWLRPLTEDLRTRHPQLDSAITLMESFYAMIRNREPTGFAPWLAQAHQSGCAAFVRLARSFEADAAAIEAALTMRWSQGPVEGTIHRLKLVKRQMYGRANLDLLVRRVLLTGRSPQKLLPYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P9</accession>
    <name>A9B8P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07713">
        <property type="protein sequence ID" value="ABX07713"/>
        <property type="gene ID" value="Haur_5085"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5085"/>
    <dbReference type="HOGENOM" id="CLU_000445_103_6_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5147-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8292" checksum="AD7932D593BE825C" modified="2008-01-15" version="1">MASKKRLSPRKMEILALVAEGKTDRHIAVLLGIGESTVKTYLHEIYTLLRVQNRAAAVYWYCQYLGLTAPIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S2</accession>
    <name>A9B8S2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07736">
        <property type="protein sequence ID" value="ABX07736"/>
        <property type="gene ID" value="Haur_5108"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5108"/>
    <dbReference type="HOGENOM" id="CLU_424997_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5170-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="644" mass="69123" checksum="9874BE5E97942211" modified="2008-01-15" version="1">MSLLILMVLFGGGGWLLMRVLATITTEQAAWVAWRVRVPAGVDAATLRDALVDGVGMGAAWLWLVPTAQGWQLLLQTTPATHTLLLTTLHARCPMATLRPVTLTVPALRWRRGGVADAQIVQGWMLRNGVVQAVHATPQRWGGSLALVWLLGLVRPQPWDGDLPLDEAALLPDLPSLSALLPAVAGVAWRFRADVALPLGTPLDLIGPAPQRWATVAQLVEQSLSAHASLVALVTPAHAATLVPMLDPLGQRLRVVDGRQPAVTTTLDVAAWLDDAAMTTLLGQLADLQPHDPLWATIPTLLAHWRSRPHPSLGDLIALAGQVLATPDQAAIDQRMAAQRWPVRLRHWRTLEWLSLFATPCDDLPLLLQRGGVVVVVLPDDVAPAAVVQSILAMAIPAWQAMSPRPILTVSDQPWAEATIQCGDQRAARVAWHGYLGGGVFPITAVLKAHGLDPWMLVTMRGLLLTHAEVCVHVADPWPTGPIAPPDAPPSHVFWQCDPTDLFQPVVALPSTAAGGVEPASALVALLDHPPTARPMPPVAQRTHDAVLRDDQLHALIEALLADRRNGVSTKQAATVLGVDRGLAERLVALVAERMAAVLGTHPRQGLLLKREVDEAEVWALVGIEADPDETDEGHEEEAVCMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8U8</accession>
    <name>A9B8U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07762">
        <property type="protein sequence ID" value="ABX07762"/>
        <property type="gene ID" value="Haur_5134"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5134"/>
    <dbReference type="HOGENOM" id="CLU_2093463_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5196-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="12858" checksum="9C581F309988CC2E" modified="2008-01-15" version="1">MTTPSFLAISIPAGQTDMQTMVYDELTKFGELYPEPPQFNVETLNLILEATKHAVEIAGGVAVALESIRRLREATQSKNIPEIQIGKEDGRQYPLSEVDEALLRELLDLPQTDTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8V2</accession>
    <name>A9B8V2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07766">
        <property type="protein sequence ID" value="ABX07766"/>
        <property type="gene ID" value="Haur_5138"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5138"/>
    <dbReference type="HOGENOM" id="CLU_096822_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5200-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="25430" checksum="37E4BF76C2C30821" modified="2008-01-15" version="1">MVDGQQGVKYNVDIVLCIDATGSMSSIIDRVKTNAIRFYDDLSSKLTSKSKNVAGLRIKVIAFRDYYDDPSDAMNISKFFNLPDELPGFTSFVNAITADKGGDAPENSLEALALAIKSDWMTSGHRRRQIIVMWTDTNAHPLDQTTFPRPSNYPGDMPNDFNKMSDWWEQGYVDLQAKRLIIYAPDTYPWTDIATNWSMVIHHTSKAGSGLSDIDYQTILDTIVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W0</accession>
    <name>A9B8W0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07774">
        <property type="protein sequence ID" value="ABX07774"/>
        <property type="gene ID" value="Haur_5146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5146"/>
    <dbReference type="HOGENOM" id="CLU_229479_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5208-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2086"/>
            <end position="2103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2110"/>
            <end position="2134"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="3">
        <location>
            <begin position="449"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1735"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2210"/>
            <end position="2234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2210"/>
            <end position="2229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2374" mass="258455" checksum="8DD1E07C2C2A91E8" modified="2008-01-15" version="1">MSLVPRWLAHLLLITLLGSGVPRASMRPTVLANPQPQPATAPVTPNNELPPLPDLPPVALPLVDTPTLRPTIPVTTTAPSPFGPLLTRISDPAIAPSPTRPRPLEADQTRAPSTPAVTPQDVSSCTGDATNPRAWWQRDSTNQYEFLNPSNVDWSHDPTGTTLQRRFFQTDRSVGIVICLRPTEQIASWVPNATTWTTTWYRSATPTSTVPTIEFGRVTMTYRGVQNGTLLFTARWNTGNEVPFDQNCTATANPCATLAPLNIDALDLKRYPGMWRAVVTSTTGMTATPPDSVMINLTVTDYEASPNPINRATPTTLTTRFQATPPTRNAQGQPSMPFLGYDYDLYTPAGQHIMTLPHPTPGFDPSTATASFATSWNNQLTNPTRPITDGTYLVSFMFAFGEPLWLGWSEPAYIQAIWPLYVGVPATQLRNKGSCEFGCSPASYQVVAGDPVNTATGNFLHSETDLSIPTEGEPLTWTRSYNSQALTETSVLGPGWTHPFHLRLVLPTSPLGVSNQISLISPSGNHYTFRQSGSTYVPLPGVYATLTADAGGYTVSLPDLTRYRFDLLGRVTTVTTSRGASLQYQYVTSGPYTGLLDRITDTSGQRFLALTYTGESAATARLASVRDPLNRTVTYGYQDGMLTTVTDVMGRITTYGLTDGLITTIDHAGVRTLTNVYETTTASVPVGNPSAWLYAAAPALTAWPPPSQRRVIAQRSGDGVETTYTYAADGTTMATRDGNRVYQEKHWYRPDGSLDHISHETSLGTITTEQATFDPVTLSRTATTDRYGNTLSQTTNARGQATSMTDATGGGVTTTYRAATEAIAPQQPALVRDSLGRETRYQYGPGDVLTSVTTGIAPTTPQGRTTTYTYDQRYPGKHWLEAVTDPLGHTTTYTYNAWGQITAVTDAAGATTTTTYDAVGRVSATTDARGTVTRYTYHPDDTVAMVVRNCTDAAGVPSPTGPCAAQTAERNLTTTYGYDPRGRQVWERSPLGTYTAQRYTAAGHVAWRTKGLVAAGFPATLPTTPPAYDARWPDQNSTTFYAYDSFGRTTFITETGIVTGSLMLDSSLGWRWTATTQRVTRLTYDAFGRPWQVMRQYDPQQPLTGRSDVNLTTTYTYDDTATPRATMICDPLNRCTRTAYDALGRVVSVIERYQDGIPGPDAADRQTVTTYTPAGLVDTVITDYHDGVYAPATDPLADLKTAYTYDSWGRATRVTTAVDPAPISGATDVNRTTQRWYDANDRLYAEQDAMGRITRYRSNAVGQVIETVTNCTGATATLLTGTCDAFTPSQPDRNLRVWMQYTALGQTEAVTTMLDLTARRTTVYRYDPLGRMTVQVDQCTANGQPVIAGCDTPNPTDTTQSDTNRRQLWIYDAEGNIVDQRNPRGFRETFTYDRLNQQRSRTYYFIGITCEPTTITCATTRQQADGTGQVRWQVDETGMDATDLRRNLVATHVDPVGRVVRTVAAADNTGQFGIVTTTQYDRGSRAIATTNADGQTTLLGYRGDDRVTTVVENATGPVAPIAVTTTAQYDVHGNLRSLTDAEQHTRRWQYDSRGLVLSQQDAANRTTTMTYDTGGRMRTKTDPRGSAMAVSYTYDLRDRVTQISSPGLATTITMQYDASGRRTQMTDGSGTTSWTYDRADRVATTTQPVVGGLQYGYDATDQRVALTYPSGGPQLGYGYDMDGLINAIDTNRDGTRDINYTHTFDGQLTSIEPIGQPFTLQWTYDALDRVTSIDQGRAAAQRQPDHRTRGQRAQPQDLVPTTTFGMRYTLSAAGRHEAITEWQQGPGTALPLPVGAYRQYLPLVLDERLDGWSLQYDGLNRLTFATLSRPGDGTPARGLVADETEGATYDRVGNPLTRQRNGSTSGPWSYTAADQRTDWTYDAAGNVLNDGTATYTYDALGRLTSRTQGGTTSTHTYNGDGLLVASTTNGATTRFLWDTTTPNAQLVGTQQASGTTWYVWSPMGGGTARVLYSLGPSGRRWLMSDGIGSVRRTLSDSGTVIQTRQWTPFGVEIGGTASAGLGYAGEWQEASGLVYLRARWYDPAASRFLSRDPWDGMISNPQTLNPYAYAHNQPTRFTDPSGKTPLLAALAGVEIGLPILSGLGAAAAACYLSIVCGVAVLTAVVVGAFGLAYLCQQGVLCQPDAATQPSDYIDTDEELFNNVDCDYIELPDGNNEGPDGLPPLRPGLKFAAIILLTTVGVVNLSQMIPRSAPQSTPESAPTAPIYTDTNPKDNDRAKQVYYRGLSNRDLREFNTYGMIRSKFIRDGGKVEDAADMINNPQARENHPYGSGGSPFVSVTKNPTMAMKFATKYLDDPTDNGSSGYILRITTTRKYYTSPTSFGHEQEALAPILIGGIFDTLEINPQQGVIPPGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W9</accession>
    <name>A9B8W9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07783">
        <property type="protein sequence ID" value="ABX07783"/>
        <property type="gene ID" value="Haur_5155"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5155"/>
    <dbReference type="HOGENOM" id="CLU_146556_0_0_0"/>
    <dbReference type="OMA" id="IAWFEEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5217-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="16053" checksum="6D87B1D6CAD49A00" modified="2008-01-15" version="1">MIDRGAPLPEDLATIAWFEEQERKSSERLDAGATILIQVITALLGILFGVFAFANLPAYLRNPQFQAFGIAAAGSLLVALVATVIVVYPRAYQRDRAFDVSTMRRIQYRVLRRKHWALRVGWWCFLLGMGMLVAMTVILLVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X3</accession>
    <name>A9B8X3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07787">
        <property type="protein sequence ID" value="ABX07787"/>
        <property type="gene ID" value="Haur_5159"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5159"/>
    <dbReference type="HOGENOM" id="CLU_996669_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="30425" checksum="F78ED37FACA646DD" modified="2008-01-15" version="1">MKGALPLITYATLITHLATILPDIDATAMTAMVAALPIDPHTPYHDGSSEPTHTDILGFLDHLGMAAEKSNHEHEAHSFYTILLQIHDQSHTRDDALIISVLIRLGKILERQPNFAAAQPIYERLIKAQSHIDGGNHHAIKRSITALGFTHQMLGNYVIAQALYTHALMLCERLDGPMHYDTAMALINRAAALGRQGLYAEAIPCFERALAIRTHLLGEHHIQTINTMGNLAVTYESDGRPVIAAALLERVDALKKEALARINAGSDPAAEVNHSASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y7</accession>
    <name>A9B8Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07801">
        <property type="protein sequence ID" value="ABX07801"/>
        <property type="gene ID" value="Haur_5173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5173"/>
    <dbReference type="HOGENOM" id="CLU_949210_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5235-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="33409" checksum="7CC4BA7D7CA82704" modified="2008-01-15" version="1">MTRNLMAYGSIPSQASMDTVFAQTTAIAFYPHPSHQTPHRWCTDRSQIASLSWVIRIHEPAEPGFAVLSLGDYALACHANNTLLATFSIDASGSLRCSRWNSDAWLCDSVGLDAWRETQGWEAEMETGWVVSSQGALFDRWWHSVPPCLREQRPLVVSYSQSNRQQMQTLLKTTYPHPSAYFSELFCWFGAGTGNWEDFPPYETLPCDLLLLEDSEPLIAYLKAPILPLHNLRGIARFLCTIPLSQAQTLIQFLPFHRVQALDQYICHWLGSSMQRQFRLRFGSLLKHSDMHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B938</accession>
    <name>A9B938_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07852">
        <property type="protein sequence ID" value="ABX07852"/>
        <property type="gene ID" value="Haur_5225"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5225"/>
    <dbReference type="HOGENOM" id="CLU_896511_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5287-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="34641" checksum="E6BE516BE269FDE6" modified="2008-01-15" version="1">MSMQREPIHWQPLTMLPTLVMMADDALAEAEEQLEHMRIAVQRPGLLDAATIDRAVGIYEEQRHFLTIYAEQGRRWQALHPTGATLRQLDAFLATTAKATTVNAELLAVLAQLQSQPTNPQDEDWYTTVGEIAMALADGRVDEALAWADDALDTSGWTARQRAELLGLRGLAWVDDGDFKEAERDYRAALALWAMLPEDADRIKHVKTWDLLIQALLHQEDFPQATEAVTTLVQLVDTHKDGLFTQPDGPRLWMATAYHRALVAEFALDYPTAATWYREAQQRAQTIALAPDHPLARLIADGIERSGQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B974</accession>
    <name>A9B974_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5261"/>
    <dbReference type="EnsemblBacteria" id="ABX07888">
        <property type="protein sequence ID" value="ABX07888"/>
        <property type="gene ID" value="Haur_5261"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5261"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_488147_0_0_0"/>
    <dbReference type="OMA" id="WELEYLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5323-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="558" mass="62858" checksum="C3128B7783F37372" modified="2008-01-15" version="1">MYQIHAGYIMPEDATQTTLDFSRLSLTILPTMQDVSWNITAIDLSYNSLTMLPYALPRAASLKRLLLRVNPLTALPECIRECHNLEELYVSGCPLTMLPDWLDELTALRILEISDTAIPDCPSVLRRLPNLRMLGIANLPWTTLPPWFCDLPLTTLTIDGMPRCDCSPLVGLKQLQHLGLSAMDYTIVPEWIRQLPLLHLLDLSHNPLEILPSWLETIPITTLMLAHVPLAALPDWHTWDRLTTLDLTACHLADAAFRMPLPRNLTHLNLDQNPITQLPSELYQCHSLYACSLANTALTTLPAWFFEDLPLVSLDISGTSLTFPALSQRSMLESFIFGMGKTSAWPYLLTHMPTLRVLDLSDTWLQSQSPSMGHALFPQLETFRGPRDQDRVPLIGAMPNLRVAVLSGGLSRGSREYLSALLGKSPQIQALDLSRWHCNPIPSTLVDLAELQTLNIAHKHLDQVPGWVNDMPYLKSLDLSDNRCTDIPRWMRNMTHLESLDLSGNPLQTFPSWLKDIPTLRDVAFMFPSVNLQCDHVLPEFLAAGIRLDVQYPRDDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC7</accession>
    <name>A9AUC7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0395"/>
    <dbReference type="EnsemblBacteria" id="ABX03046">
        <property type="protein sequence ID" value="ABX03046"/>
        <property type="gene ID" value="Haur_0395"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0395"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_0"/>
    <dbReference type="OMA" id="YKQFYGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-398-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="129"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="21904" checksum="7D4DB068CAFEC190" modified="2008-01-15" version="1">MTDAERQWVSAAKDGDVEAFNQLVRMYEGRVYGLAYRMLGDSDSAADVAQDTFISAFKAIKRFREGSFAAWLLRIATNACYDVLRAQKRRRTTSMDQLLAGDDDSPGEQFEDQSLPLDQHMINRELQAAIQAGLATLPEDQRAVLIMCDIQGFAYEEIAAATDTQLGTVKSRLSRARAKLRDYLKSRELLPTAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI6</accession>
    <name>A9AUI6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1870"/>
    <dbReference type="EnsemblBacteria" id="ABX04513">
        <property type="protein sequence ID" value="ABX04513"/>
        <property type="gene ID" value="Haur_1870"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1870"/>
    <dbReference type="HOGENOM" id="CLU_1832419_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1899-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15929" checksum="0AA074EEF6CDF835" modified="2008-01-15" version="1">MKPTFYRQEALEVYLKQQTTINPLSIDESRPRYWLWLIICGLGLGLSWLLLQPQPQQPNSSASVINQRQIRYQTKQSVMLNQIVNVYVNQVAISATVAQVNPHQDATTVVLTLPTLVYPADQLVIFEDSQTLGSLLMNSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI7</accession>
    <name>A9AUI7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">(S)-2-hydroxy-acid oxidase</fullName>
            <ecNumber evidence="7">1.1.3.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1871</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.15" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1871"/>
    <dbReference type="EnsemblBacteria" id="ABX04514">
        <property type="protein sequence ID" value="ABX04514"/>
        <property type="gene ID" value="Haur_1871"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1871"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_0_0"/>
    <dbReference type="OMA" id="FTRLMQT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1900-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003973">
        <property type="term" value="F:(S)-2-hydroxy-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="287"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="310"/>
            <end position="311"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="38599" checksum="9A7F648CB49B8A9C" modified="2008-01-15" version="1">MPPINLMDYQPLAKQLIDRSAWDYIQGGSDDEITLQANQAAYTKLKLRPRVLVDVSQCTLETSVLGQTIAMPIGIAPMGCQGLVHAEGECAMARAAEAAQTVMIASAMANYSLEAIAQAANGPLWFQLYVYRERQITEALVRRVEAAGYQALVLTVDVPFLGRRERDLRNGFALPQHLHFANFAPTDAAGQHQQTLGASGIATHAAGRFDAALTWEAIDWLRSLTRLPIVLKGILSAEDAQLAVQHGVDGLIVSNHGGRQLDTVAATIECLPAIVDAVGSTCEVYLDGGIRRGTDVLKALALGAKMVFVGRPLLWGLAVDGQQGAHHVLELLRSEYSLALGLIGCPHSHQLNRHYISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY2</accession>
    <name>A9AUY2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3936"/>
    <dbReference type="EnsemblBacteria" id="ABX06570">
        <property type="protein sequence ID" value="ABX06570"/>
        <property type="gene ID" value="Haur_3936"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3936"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048252_1_0_0"/>
    <dbReference type="OMA" id="FFAMGNG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3978-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="243"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="438" mass="47612" checksum="23C616C68D113C99" modified="2008-01-15" version="1">MVFASKARQVMEQQDINANVRHNVVVNVADGAFFGAATGIASFVTVIPLFMHTLTDSATLIGLVSAIHSVGWQLPQLLTARRVASLRRYKPMVLLMTINERLPFFGLALIAWFAADLGRELALWLAYMLLIWQGLGGGLTATAWQTMIGKIMPHRWRGTFFGVQSAAANLLASIGAVAAGVILDKLPSPIDFVVCFGVSGVAMFISWSFLAWTKEPSREPEHTHGSQRDFWASIANILKRDRNFRWFLASRIISQLGLMATAFFTVYAVQRFGLDDQTAGIMTALYLIIQTVANPIMGWLGDRIGYRRVMEVGALLALGAGLGAWLAPALGWFYLIFAIAGVANVAFWTMAMAMTLEFGSLAERPSYIGLANTLTAPATLVAPLIGGWLADSAGYNYTFAVAAAGGLLTWLILRFAVRDPQSVTYSEAHAEPQVVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV27</accession>
    <name>A9AV27_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ordered locus">Haur_0454</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0454"/>
    <dbReference type="EnsemblBacteria" id="ABX03105">
        <property type="protein sequence ID" value="ABX03105"/>
        <property type="gene ID" value="Haur_0454"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0454"/>
    <dbReference type="eggNOG" id="COG0321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035168_1_3_0"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="37"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24964" checksum="24855D73E87EDDDC" modified="2008-01-15" version="1">MTIQQTQRLLKVQILGMLDYNAAWELQRELVSQRSAETIPDTLVLLEHPATYTIGRSGGYEHLLVSPETLQQRGAALIEVDRGGDITYHGPGQLVGYPILQIRDHGRDLHQYLRMLEAVIIELLAEYGLSARRFPGYTGVWVGDRKIAAIGVRSNTRGVTSHGFALNVTTNLADFTAIVPCGIHDYGVTSLAELLPVVPAFNDVQQRLIRIFLRVFDLHLIEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV52</accession>
    <name>A9AV52_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="7" type="ordered locus">Haur_0479</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0479"/>
    <dbReference type="EnsemblBacteria" id="ABX03130">
        <property type="protein sequence ID" value="ABX03130"/>
        <property type="gene ID" value="Haur_0479"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0479"/>
    <dbReference type="eggNOG" id="COG0130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_0_3_0"/>
    <dbReference type="OMA" id="ELQFIRW"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="24"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="174"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="31393" checksum="61F81C4B0CFC780A" modified="2008-01-15" version="1">MLHGFLNIDKPQGITSTDVVRVVKRNARQKRVGHGGTLDPMATGVLPIALGNATRLLEYLLEEERKAYTATLRLGITTDSDDVEGAVIAEAPIPPLDPALIESVLSQFRGAINQVPPQYAAIRVDGKRMYEYAREGKHIELPARPITIEQLDLLAWDAQQLTIAVDCSKGTYIRAIARDIGALLGCGAHLTALRRTRAGAFDLSNSIGLAELDQQPEVFAAALLPPQAAIANWPLINLADAIVADVRMGRVVQVDSQAERVGLLDQAGQLVAIAVLREAGYQPIKVFAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV58</accession>
    <name>A9AV58_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0485"/>
    <dbReference type="EnsemblBacteria" id="ABX03136">
        <property type="protein sequence ID" value="ABX03136"/>
        <property type="gene ID" value="Haur_0485"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0485"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054927_3_1_0"/>
    <dbReference type="OMA" id="HVETICG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-491-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="51"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="301" mass="34156" checksum="F85CE4F9CE93D07A" modified="2008-01-15" version="1">MRFKTTSGASGDLFNPEFLARIERLALRSRRNLRGGLSGEHASRRRLPAPTFSDHRAYSPGDDLRHVDWFAYARHEDLHLKLGETEQDINVTIALDCSASLDWGHGELHKGRYALRLAAMLGYLGLTSNDQTTIWPFTSKLIKPFGPMVSRARGPDMLRYLSNLNWAEQTSFTPVIQAVRRSAGGMLLIISDLWTSDLEPLLRAAAPPVWQVVVLHLLHPEEIKPTLTGPVEFEDSETGQVLALELDQQTHKAYREKLVRWVRMHEQVCQRYGATYAGIRTDRPLEQSILPFLRRRGIIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA9</accession>
    <name>A9AVA9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prok-JAB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0539"/>
    <dbReference type="EnsemblBacteria" id="ABX03187">
        <property type="protein sequence ID" value="ABX03187"/>
        <property type="gene ID" value="Haur_0539"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0539"/>
    <dbReference type="eggNOG" id="ENOG5033HCC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099830_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-548-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prok-JAB" evidence="6">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="217" mass="24338" checksum="0B6949D670E3F464" modified="2008-01-15" version="1">MIPNLHRYHIVTEAEPYPPNQPGLTWLIAANGIFKSGCDRHQRLIIQVSEQRIDLPGMVAIMPMIHWFNYPKRLPSAWLSMLLADAQKASIITNGVARPIEKQYFVVNKDDRLKLIIAPQQASALRVHYQMPSAPIFVDIHSHHGMPAYFSATDDADDTGLSISCVIGNIYSNPEIICRLNIYGQHQVVPITTIFDGCGPFADVGQREGDRYANAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE6</accession>
    <name>A9AVE6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1994"/>
    <dbReference type="EnsemblBacteria" id="ABX04637">
        <property type="protein sequence ID" value="ABX04637"/>
        <property type="gene ID" value="Haur_1994"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1994"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_0_2_0"/>
    <dbReference type="OMA" id="ENSHRET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2023-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731662" description="FGE-sulfatase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="59"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33839" checksum="AEB29F194BA28685" modified="2008-01-15" version="1">MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQVWVPAGCFMMGTDPATLTETPPAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFIDAGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCITWYEAEAYSRWRGGRLPTEAEWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQDWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVRVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL5</accession>
    <name>A9AVL5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3983"/>
    <dbReference type="EnsemblBacteria" id="ABX06615">
        <property type="protein sequence ID" value="ABX06615"/>
        <property type="gene ID" value="Haur_3983"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3983"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_18_0_0"/>
    <dbReference type="OMA" id="EGSGRHK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4025-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="25599" checksum="BE7486CB496C95F6" modified="2008-01-15" version="1">MKLLLWDIDGTLIRSHGRSLEAFKAAFQRVYEVDLPLSSTAGKTDGLIVRETLHSWEEAAILERLEQFYAVYEGELQARFEYLQRETTILHGVHSALSHLQPHTIQSLLTGNLQRTAKIKLDAVDLSRHFRWEWGAFGSDSHIRNDLVPVALQRAQAAGWHGTFDDVVVIGDTPFDIACAKIAGACSVAVASGKFSREQLSEHQPDLLLENLGELAQLQAFLGVADEIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR1</accession>
    <name>A9AVR1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4029"/>
    <dbReference type="EnsemblBacteria" id="ABX06661">
        <property type="protein sequence ID" value="ABX06661"/>
        <property type="gene ID" value="Haur_4029"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4029"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="SVWDVVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4071-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="27136" checksum="059910136A386850" modified="2008-01-15" version="1">MNASAKPLAIHDLTVAYQDKPVLWDIDLSVPTGVLAAIVGPNGAGKSTLIKATLGLMPVAAGTVEMFGQPYAKARRMVGYVPQRSSVDWDFPTNALDVVLMGTYGQLGWIKRPSKADREWALHCLEQLAMADFAQRQISQLSGGQQQRVFLARALAQRAQLYLMDEPFVGVDAVTERAIISLLQQLRSDGKTVICVHHDLDSAPEYFDWVALLNVRMIAAGPMKTIWTPENISQTYGGRTQSLIRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY2</accession>
    <name>A9AVY2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0572"/>
    <dbReference type="EnsemblBacteria" id="ABX03220">
        <property type="protein sequence ID" value="ABX03220"/>
        <property type="gene ID" value="Haur_0572"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0572"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094111_0_0_0"/>
    <dbReference type="OMA" id="SKYAEPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-581-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="29025" checksum="1377BB0988501A36" modified="2008-01-15" version="1">MEQELIFRALADPSRRQLLDLLFERDGRTLKELEAALPMTRFGVMKHLRVLEEASLIVTRKVGRERLHYLNPVPIQLISDRWINKYAAARAMALVDLKMVLEGGSSMTTAAKPKLVYQTIIRASQQQVWEAIIKPEFTTRYYYGCTVDTNLAVGSAFNYQRSNGAAIVEGQVVEVDAPNRLVHTYHSLWPPMNEDAPTKVTWELEAMPGGITKVTVVHEDFQGETATYQGLNSGGWTWILSNLKTLLETGEALPEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW04</accession>
    <name>A9AW04_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_0594</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0594"/>
    <dbReference type="EnsemblBacteria" id="ABX03242">
        <property type="protein sequence ID" value="ABX03242"/>
        <property type="gene ID" value="Haur_0594"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0594"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_332286_0_0_0"/>
    <dbReference type="OMA" id="TDPYIFF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-603-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="377"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="638"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX03242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="880" mass="96966" checksum="835137A7A55BC253" modified="2008-01-15" version="1">MTSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAENMLMSRAIDKAELYDQALLSVQRQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLIPPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGVMVLDDVRVVSVLPDGFDARKRPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLRIDAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMAGVTRLQLDGGDRYLAYSPMRTVGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAVLLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQELVVHGNDEIGRLSLSFNQMTTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLRDEVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQVIQAKQFISGGDSYVQAPILGREKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIENAFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASISHELRTPLNAIIGFSTVLLDELSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDIMHGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQEATPIGSHYLLPGDWIVISVQDTGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRRLVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW59</accession>
    <name>A9AW59_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2069"/>
    <dbReference type="EnsemblBacteria" id="ABX04709">
        <property type="protein sequence ID" value="ABX04709"/>
        <property type="gene ID" value="Haur_2069"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2069"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043663_0_0_0"/>
    <dbReference type="OMA" id="MGRTIRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2097-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="114"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="37415" checksum="2F07C85FB6E0E9E0" modified="2008-01-15" version="1">MADLAPTVGIAAACRVLGVPRSAVYRAAPPAPAAVPRRRPARALTPNEVAHIRTVLNSDRFADCTPRQIYATLLDEGTYLCHWRTMYRILAAHREVRERRNQLRHPTYAAPELLATGPNQLWSWDITKFKGPTTWSYFYAYVILDVFSRCIVGWMVMERESAALAEQCIAETYHREGIQPNQRTLHADNGSAMTAKPVAQLLADLGVTKTHSRPHVSNDNPYSEAQFKTTKYRPDFPDRFGSLIDARAWMRAFVQWYNHDHCHSGIGLLPPAVVHHGQASAMTTARQQVLATAYAAHPERFVRGTPRPPRVPQAVWINRPAGPADPSITAALRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR6</accession>
    <name>A9AWR6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0669"/>
    <dbReference type="EnsemblBacteria" id="ABX03317">
        <property type="protein sequence ID" value="ABX03317"/>
        <property type="gene ID" value="Haur_0669"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0669"/>
    <dbReference type="HOGENOM" id="CLU_1260003_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-680-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="25125" checksum="E7B878A22CA46DAC" modified="2008-01-15" version="1">MNIPDEEYPTISSIASLTDEEFAFLIESITQTPVRYHPRSFAAAVSEKFKYPHIDAERIIRTIISLYGVKSQIPTSTDKLVPSIINAFVQRNPEISDAVIQNLGQRLERLLTLYSPLGIVASAYKVASDSERCIVDTHTFLDLRPIFNDDNQELLSNVILYRLKLTYENNDEQKDINFTFDIYDVLKLRYQLDLLIEKSNNLQEKLESVNIHILDSNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWS6</accession>
    <name>A9AWS6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0679"/>
    <dbReference type="EnsemblBacteria" id="ABX03327">
        <property type="protein sequence ID" value="ABX03327"/>
        <property type="gene ID" value="Haur_0679"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0679"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_9_2_0"/>
    <dbReference type="OMA" id="ERMVYFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-690-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="102"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="32974" checksum="3AF32C9F9863F224" modified="2008-01-15" version="1">MITQWIEEYLSAKIAERRSPATITTYRIRLGRFGTWVLEQPNQVLTRALLRAYSAYLAQQNISITSHYSYLNDALVLVRWLAEEGYIQPVKTDKLKPRLPKRLPAHYTMDQIKRLLLVAELREKAMLCVLLDTGVRVSELIQLRRTSFDSEGCAMILGKGSKDRYIWISSVTQEVLRTYIASRTDTNPALFVSHRQQKTLTISGVHQSFDRVASDAEIRNDVRRLIHSFRATFARELIKKGLDAESLRVLMGHETIQMSLHYAQLSSHEATQNRQGVNLLEKVESCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX00</accession>
    <name>A9AX00_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2168"/>
    <dbReference type="EnsemblBacteria" id="ABX04808">
        <property type="protein sequence ID" value="ABX04808"/>
        <property type="gene ID" value="Haur_2168"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2168"/>
    <dbReference type="HOGENOM" id="CLU_1658411_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2196-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="18263" checksum="2F84352DC6C0CA40" modified="2008-01-15" version="1">MVVHRFSLYLLIWISIVGCQSEAAARLMPQPTPTIPIDTLYFSTTPIKEAGLIDGMLIVASTEELYRHLNESEIQIVYLDQTTVDQITHEALSMIYQKSIVIAAFDIPISMLAKKAGHPQKIPDLELRQPRQYISAIYQFSNNLKRMYGEYTDFFLCRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX61</accession>
    <name>A9AX61_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2229"/>
    <dbReference type="EnsemblBacteria" id="ABX04869">
        <property type="protein sequence ID" value="ABX04869"/>
        <property type="gene ID" value="Haur_2229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2229"/>
    <dbReference type="eggNOG" id="ENOG502Z850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_836051_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2257-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017574">
        <property type="entry name" value="CRISPR-assoc_prot_Csc2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18320">
        <property type="entry name" value="Csc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03157">
        <property type="entry name" value="cas_Csc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="37116" checksum="43A54BC775EE2923" modified="2008-01-15" version="1">MSILNTYQNYLMDQYNPYPHGRFVSLFIVRHVESEAMFRTEGSGEPLNREFVFAGKQGGDNQLIQRVVISKRKQIAVERRMGRELLREYALLQKTAKGEGICSLNTNNPCERCIDCMVYGYAAGGGGAQRSRVITDDAFSLHSAATIIGTRQFNALFDNSTMRNPETGEPSTSIGTDEYVKPESVFLDIETLKDVTADEFRYIVGNILRSSRYGAISSRIGKTRNNLIGVAWSNCELFSNLEWVQETYELLREDQHEPSFPLHTSAVAKAAQSAMQTLRQRVIGQVNWLNSDELGNLVDELGQLYANPEQLKAMLSRLATSYPMTQKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX91</accession>
    <name>A9AX91_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4179"/>
    <dbReference type="EnsemblBacteria" id="ABX06811">
        <property type="protein sequence ID" value="ABX06811"/>
        <property type="gene ID" value="Haur_4179"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4179"/>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062599_0_0_0"/>
    <dbReference type="OMA" id="IVMRPDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4226-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="87"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="36726" checksum="AEA2A02C7A6E4197" modified="2008-01-15" version="1">MIVVMKAHADLADRDAVLARLAENKLKGHLSEGEERIVIGVVGAKIPAGLEEQLQSMSGVQTTLRITRPYKLAGREFQQHNTVIRIGDLEIGGGTPVVMAGPCSVESAEQLLSTAHAVKAAGANILRGGAFKPRTSPYAFRGLGEEGLKILAQAREETGLPIITEALNTRDVELVARYTDIIQLGARNMQNFALLEEAGQTGKPIMVKRGPSATVEEWLLAAEYILATGNRNVILCERGIRTYETATRNTLDLNAVAVAKRRTHLPVIADPSHGTGKWYLVQPMALAGLAAGADGLMIEVHHDPDRASSDGPQSLNHHNFAQLMQQVRRLIAALEPELAVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC6</accession>
    <name>MURI_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate racemase</fullName>
            <ecNumber evidence="1">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murI</name>
        <name type="ordered locus">Haur_4214</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXC6"/>
    <dbReference type="SMR" id="A9AXC6"/>
    <dbReference type="STRING" id="316274.Haur_4214"/>
    <dbReference type="EnsemblBacteria" id="ABX06846">
        <property type="protein sequence ID" value="ABX06846"/>
        <property type="gene ID" value="Haur_4214"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4214"/>
    <dbReference type="eggNOG" id="COG0796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052344_1_0_0"/>
    <dbReference type="OMA" id="MPWGPRT"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114049" description="Glutamate racemase">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="42"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <sequence length="254" mass="27269" checksum="978ADF7982E2239A" modified="2008-01-15" version="1">MKDQPIGMFDSGVGGLSTLRDLRALLPHEDIIYYADTGNCPYGGRSHEEIVALSERITYILLERGVKLIVVACNTATLHAVDYLREHFSISFVGMEPGIKPAIAQTKTGVVGVMATQATVAGERFQRLIARYAGDVQVVPQACPGLVELIEAGELQSETTRDAVARYVAPLLKAGADTIVLGCTHYPFLRSLIADVAGPNVALLDTGAAVARQTQRLLAAADLLNPQTSQGSIEWLTSGDPAHFAKIRQCLEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE4</accession>
    <name>A9AXE4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4232"/>
    <dbReference type="EnsemblBacteria" id="ABX06864">
        <property type="protein sequence ID" value="ABX06864"/>
        <property type="gene ID" value="Haur_4232"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4232"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1183746_0_0_0"/>
    <dbReference type="OMA" id="ENHAKEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4279-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="39"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="26331" checksum="67051C2AA8353C5B" modified="2008-01-15" version="1">MHESDLIRHYATIPVGTSFVRPVDVLHLLQNQPIAAKPRIFDVGCGQGQVAIAMAQAWPDAEIIAIDLSPEQIVKARQAAAQAGINTIQFGAADWREFELPRSGVDIIVATQVIQFMPDEHAFVEYLADALALDGQLLLRSVLLPEEEPGRSFVEQVVQQWIAHSIRFYSERNLTDLLRECGLSRLRIDKEEMWLDNLPAERQASLNRALQQHSLGIDDVQQWFWSGSISGVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH8</accession>
    <name>A9AXH8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ordered locus">Haur_0744</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0744"/>
    <dbReference type="EnsemblBacteria" id="ABX03392">
        <property type="protein sequence ID" value="ABX03392"/>
        <property type="gene ID" value="Haur_0744"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0744"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_3_1_0"/>
    <dbReference type="OMA" id="WGSEGDK"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="106"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="237"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="34970" checksum="2B09FD08D0B1DC37" modified="2008-01-15" version="1">MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAARIALDKAGVKPEELDLIVVATTSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALSAVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDAAGAVILEATEQERGLQSYKLGAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVGKTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGRMQPGDTILLTAFGGGLTWASGVLVWGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI1</accession>
    <name>A9AXI1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0747"/>
    <dbReference type="EnsemblBacteria" id="ABX03395">
        <property type="protein sequence ID" value="ABX03395"/>
        <property type="gene ID" value="Haur_0747"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0747"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_0"/>
    <dbReference type="OMA" id="DVNCGEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-759-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="26819" checksum="313289036EA754FA" modified="2008-01-15" version="1">MSINDQVAIVTGGTGAVGREVVSGLIQRGARVVFCYRQRDDLAEEMCDTIADEQRLIAIKADVRDAEAMNSLVEVAVRRWERLDMLITAHSAVNNAPVADMTLEQWNDVMDVMLRGVTRITRAVLRPMQKARYGRIITITGYQPLAGGLTQANYAAALGGIIGFSKSLAREVAPWGITVNSVAPGLISRPHMSSFDPSYIPWATNIVPLKRLGAPAEITPAIFMLANPEAGYITGQVLPVDGGWRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK2</accession>
    <name>A9AXK2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0768"/>
    <dbReference type="EnsemblBacteria" id="ABX03416">
        <property type="protein sequence ID" value="ABX03416"/>
        <property type="gene ID" value="Haur_0768"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0768"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061385_1_0_0"/>
    <dbReference type="OMA" id="GPRYIAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-780-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07726">
        <property type="entry name" value="ST1585-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037482">
        <property type="entry name" value="ST1585_MBL-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="26"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="33480" checksum="A626564A58B7914C" modified="2008-01-15" version="1">MMQVPLTQLSDHIAMIDNGLLTTDGFGATYVIQGDQVALIETGTSLTAEATLAGLQQLGIAPEAVEHILLTHVHMDHSGGAGILAQHLPNAKVYLHSMTAEHLIEPSRLMRSVERAVGQMWHVYGTMLPIAAERMLAAEHLKLNLGKGIVLQAVPTPGHSPDHLAFWEAHSGTMWAGDSIGILMSTFNLNMPVTPPPAFNLADQLQAFQTLAQYPIRQLLPSHFGPTVAAPALAIEEMHQRLVKIVRDVRDHLHLTELPVEAIVERALPTNEPVSPALNLVLWGNLSMSVRGLKLFFERNPQAVELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK8</accession>
    <name>A9AXK8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0774"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03422">
        <property type="protein sequence ID" value="ABX03422"/>
        <property type="gene ID" value="Haur_0774"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0774"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038143_0_0_0"/>
    <dbReference type="OMA" id="GWLGKPH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-786-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="45"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="42529" checksum="C8024EDD7EF82907" modified="2008-01-15" version="1">MLPVVIGLLLGLASLILLVRDALLLNKIPKIEPRPSPEPMPSVAVLVPARNEAQNIGHVLRGMAQQTRSDWQLTILDDHSTDATAAIVADVAAQDQRVHLLQGQALPAGWTGKCWACWQLAEASTSEWLLFLDADTKPQPEMLQQALAYAEAEKLDLLTFLPFSELGSFWEQTLLPAFFSIIQAAYPVSKVNTPGSGVVLANGQFILVRRSAYQRAGGHAAVRDRVLEDVELAQAIVRAGGVMRAVYAGELLRVRMYTKGSEVREGLVKNAIAGLRNGGVRSSWAGLRQILVGVVPFGLGLLSLWAWLRRWTFWPKILLSAMAVLLNGFALWSWGRFMQQLYGLSRRHALLFPLGIVCYMLLAAEAAWRIWSGRGVTWKGRTYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY84</accession>
    <name>A9AY84_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4334"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="DNASU" id="5736194"/>
    <dbReference type="EnsemblBacteria" id="ABX06966">
        <property type="protein sequence ID" value="ABX06966"/>
        <property type="gene ID" value="Haur_4334"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4334"/>
    <dbReference type="eggNOG" id="COG1501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008294_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4387-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="616" mass="70072" checksum="7861438A89FA25D9" modified="2008-01-15" version="1">MAYTLESTGLLVFQRDDEEVLTIQPYLQAYGSQFAALGVQTKPDTVQYTSFDNQTFELNLETTATGYQLVFHVKHQVAQIGLAIGVQPAGSWYGMGERVIQSWPLNLAGVQSQPFMTYDHANDGTLNIVTPAWIGANGVAFIVAEDTGPLHVTIDSDPAGVIRLVQFPSPTPFGAGLDGSETHYEGTRLVLDLLIAENVSVAAQHVIQQLGYPKAAPPLAMFSKPIWTTWARYKMDIDQAQTLAFAQEIIDQQYPYSVLEIDDRWQTAYGDLEFDRRKFPDPKAMVDQLHQLGYKVTLWIPPFFDPKSAAFAEATANGYLVKHPANDQPYLTRWWQGWGGLLDVSNPAALAWWQAGLERLQTLYGIDGFKFDGAEGNFLPAEAKTHLPMTPNQYSDRYVAFVAKSWQWTEVRTGWRSQQQPIFFREWDKWSRWGMDNGLHAVVTQALAMSVIGYPYVLPDMIGGNAYNGEFPERELLIRWTQVTALLPAMQFSIAPWQYDVETSQICQRYAQLHAELEPYIAELVQATITDGTPLVRPLWWHYPDDASTRFIGDQWLFGEQYLVAPMLQANHYQRDIYLPEGGWRDYWTGEKFEGETWLYNYPAPLETLPLFERLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY96</accession>
    <name>A9AY96_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allophanate hydrolase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4346</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4346"/>
    <dbReference type="EnsemblBacteria" id="ABX06978">
        <property type="protein sequence ID" value="ABX06978"/>
        <property type="gene ID" value="Haur_4346"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4346"/>
    <dbReference type="eggNOG" id="COG2049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020207_1_0_0"/>
    <dbReference type="OMA" id="PWIMSEK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4399-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00370">
        <property type="entry name" value="TIGR00370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS1" evidence="4">
        <location>
            <begin position="2"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="201" mass="21778" checksum="211C26664E936BD6" modified="2008-01-15" version="1">MLKIELFGDSALLITTPQPAQLALALRHARLRGVIDVVTGLATVTVLFDLQLTNARQVRRQIQRLQSGQSNLPTPTIHRIPICYDGIDLAEVAERCQLTIDQVIGFHSSAEYRVAMVGFLPGFPYLDGLPAALHLPRRATPRAKVAAGSVAIANDQTSIYPQSSPGGWHILGTTPLRLFDPQADPPALLNAGDLVYFAPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ50</accession>
    <name>A9AZ50_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0948</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0948"/>
    <dbReference type="EnsemblBacteria" id="ABX03596">
        <property type="protein sequence ID" value="ABX03596"/>
        <property type="gene ID" value="Haur_0948"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0948"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="RYFEVMD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-962-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="38"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="388"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="422"/>
            <end position="429"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX03596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="642" mass="69813" checksum="E9520D259CB867FF" modified="2008-01-15" version="1">MQAQMGKPQAQRGQKAGGGSGGLGRAIAYLGAQRKSAILAYVALALATLAQLAVPQLVQNMIDAVTSGSIARIIFKQVPEPMQAAAAQQAGTTIEQLRLDQTNAESLLINAALIIVAFAFMRGIFSFVQAYMAEKTSQGVAFDLRNQIFARVQRLSFSYYDQNQTGQLMIRATDDVEKVRTFIAQGLILTAQALLLLVGALVILFFTNWKLSLVVVPLLPVAMVMFMIFGKVSQPLFGVVQRKLSALNTILQENLAGIKVVKAFTREPYESQRFDLAATDLMSQQLRISKVFSFLFPVIFLVAQLGQAGILYFGGRQILGGTLDLGEYQKFSLYLVYVFFPLGQLGFIISLMAQAGASASRIFEILDAKSEITDKPDAQELPAIQGNVEFRNVTFRYFGSSDPVLRDVSFEAKPGQTIALLGATGSGKSTIINLLPRFYDVSEGAVLIDGHDLRDVKLDSLRSQIGIVLQETNLFSGSIRDNIAFGRPEATFEEVEAAAKAASAHDFIMTFPQGYDTSVGERGATLSGGQKQRIAIARALLLNPRLLILDDSTSSVDLMTEYRIQKALDQLMQGRTSVVIAQRISTVLNADQILVLEKGQVVARGNHEELMESSAIYAEIYNSQLVGDADIAALESSSVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE3</accession>
    <name>A9AZE3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2449"/>
    <dbReference type="EnsemblBacteria" id="ABX05087">
        <property type="protein sequence ID" value="ABX05087"/>
        <property type="gene ID" value="Haur_2449"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2449"/>
    <dbReference type="eggNOG" id="ENOG5032RGN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091706_0_0_0"/>
    <dbReference type="OMA" id="LNMWVRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2476-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018960">
        <property type="entry name" value="DUF1990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09348">
        <property type="entry name" value="DUF1990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1990" evidence="2">
        <location>
            <begin position="114"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="24241" checksum="07085CAF2F0E79D9" modified="2008-01-15" version="1">MQRRQFGWMFGLGLGAIGLVQLWQRRFKRGKATQTPQAGSGSLYRRRYWVDFQALNQSPESLVKHIKANLPDFSPGLFADFRKATGNERVMQVGDEYDIAILGPWNGSVRVSTSQPLRFGFCTLEGHPEAGQIHFELKPHPERSNTWRFEIASEARSRDGLVEMAYRIGKVVQTQVWSTFCQRVVEFAQAQQLGEIQTSTIEQTPEGEVVIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS4</accession>
    <name>A9AZS4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4496"/>
    <dbReference type="EnsemblBacteria" id="ABX07128">
        <property type="protein sequence ID" value="ABX07128"/>
        <property type="gene ID" value="Haur_4496"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4496"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095996_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4551-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="179" mass="20833" checksum="7807B818B244644F" modified="2008-01-15" version="1">MNEIQLRRLNWPHDRAAIGLLDTSFSTTTIYQLHQTELTMHLALVDLASPFEKHYDLSEDYARLPQHDWVLVAEDQSQVVGLAAVEYQQWNRRAVLEHCYVDRHYRGRGLGRQLLTAAIAAARQLSARCLWLETQTTNPAAIEFYRTVGFRWCGSDWQLYDPFALDPREIALFFSYDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZX3</accession>
    <name>A9AZX3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1032"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03680">
        <property type="protein sequence ID" value="ABX03680"/>
        <property type="gene ID" value="Haur_1032"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1032"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_2_0"/>
    <dbReference type="OMA" id="NLYPPQE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1049-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="221"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="46485" checksum="CE5577383B3843B9" modified="2008-01-15" version="1">MQPLKILVLTSLFPPHYIGGYEVGCGDVVAGLRAKGHDVTVLTSTYGVDREVREGFIERSLTIDIHPVAQTTLAHQRRLYERELHNQPRILALAEALKPDIVFVWSFYQASMSAVRMLQARGYRTVFFISDHWPIRIGIFDPWHYMPRHPVRWLGRKLLGRKLGRKTGFRNHLPLSYANAIFASDFLLKQTQPIGSMPNAQVIRWGVDYDLFVRRERSASMGQRLLFVGQISGHKGMETLLEAFALVQQKHGFEQATLSIVGAGLSAEYTSEMQRYAETLGISQSVAWRGKLPRQALPDIYASHDILIFPSRWDEPFSITVVEALAMGLVVVASDTGGTTEIIKHEQTGMVFARDDAASCADHIATLFTQPALAQKLHNQATQIVDREFRMSTMIDRVEAALYAACNKDSHHD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY8</accession>
    <name>MIAB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName>tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber>2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">miaB</name>
        <name type="ordered locus">Haur_1047</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZY8"/>
    <dbReference type="SMR" id="A9AZY8"/>
    <dbReference type="STRING" id="316274.Haur_1047"/>
    <dbReference type="PRIDE" id="A9AZY8"/>
    <dbReference type="EnsemblBacteria" id="ABX03695">
        <property type="protein sequence ID" value="ABX03695"/>
        <property type="gene ID" value="Haur_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1047"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_2_0_0"/>
    <dbReference type="OMA" id="CEHFHIP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
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        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
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        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000374342" description="tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase">
        <location>
            <begin position="1"/>
            <end position="438"/>
        </location>
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    <feature type="domain" description="MTTase N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="4">
        <location>
            <begin position="134"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="371"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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            <position position="155"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="438" mass="49686" checksum="A980B4D6005D61CA" modified="2008-01-15" version="1">MERNRYFVWTVGCQMNVSDSERLESALQGVGYTPAEQAEDADFIVLNSCSVRANAEEKIIGKITDIQRIKRERPDTKIVLWGCMVGPNNQSIFKKKLPMVDHFVSPSAVDEVLALAPNPIYQLDEPALPVADWQVPPVNVHVPINYGCNMSCAYCVIPLRRGKERSRPMEEIAEEVRRICARGAKEITLLGQIVDSYGHDLPGRPDLADLLEYLHETPGLVRLRFLTSHPAFMSEKLLHTIARLPKVMPDINLPIQAGDDQLLKVMKRGYTVAKYTKLIERIREIIPNVSLSTDIIVGHPGETREMFERTLEMVENIRFDKVHIAAYSSRPGTKAADMELDPALAVEHGEKQYRRIALERLQERIATERNEECLGHEVEVLVEEFTKGKWRGRDRNNKLVFFEADGDWYGKVVNIHVTETRPWWLGGNLIGETLAIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B011</accession>
    <name>A9B011_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX03718">
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        <property type="gene ID" value="Haur_1070"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1070"/>
    <dbReference type="HOGENOM" id="CLU_1432755_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1087-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731764" evidence="1">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="20554" checksum="DE300FBA1F128594" modified="2008-01-15" version="1">MRKLVPIILIAILLSGCTMPATTPPRDLPTTVVTTAPIRMADTIPSATAVPSAVPAPTPTWDESESEYAGCETVSETLPIYPQRLLYPDYRDLSQTITTSELPLVRHTTYRSSAAADTILAWYREQARAAFWKEISVTTTTIKYDYGAIGMCGPVFAITIAVTGDAEGSMVAFTREFSGPFSPLDWPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B059</accession>
    <name>A9B059_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeS_assembly_P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2530"/>
    <dbReference type="EnsemblBacteria" id="ABX05168">
        <property type="protein sequence ID" value="ABX05168"/>
        <property type="gene ID" value="Haur_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2530"/>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091588_2_2_0"/>
    <dbReference type="OMA" id="PPWGPER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2558-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="105" mass="11734" checksum="E562AA9EC34D5474" modified="2008-01-15" version="1">MLSDDMVRSALKNVVDPEIGVNIVDLGLIYNVDIRDEGRQVVVDMTLTTPACPAGPQIIDQAHKEVKALEVIHPSLNDVNINLVWTPFWNPEMMSQDAKDELGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A5</accession>
    <name>A9B0A5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ESAT-6-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WXG100 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2576"/>
    <dbReference type="EnsemblBacteria" id="ABX05214">
        <property type="protein sequence ID" value="ABX05214"/>
        <property type="gene ID" value="Haur_2576"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2576"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2273491_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2604-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="102" mass="11774" checksum="3892131FD677DC50" modified="2008-01-15" version="1">MAAETVQFDRNVLDQVASRFGKLAQSSQQLMQMLTQLSQTLRTEWLGDAATSYHAEWEQDIKPAYTRLIEAFNTFQSTTNEIKKTFEQHEEEAAGIFKAWQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0D8</accession>
    <name>A9B0D8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2609"/>
    <dbReference type="EnsemblBacteria" id="ABX05247">
        <property type="protein sequence ID" value="ABX05247"/>
        <property type="gene ID" value="Haur_2609"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2609"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_7_2_0"/>
    <dbReference type="OMA" id="HPQMIAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2637-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041478">
        <property type="entry name" value="TetR_C_27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17935">
        <property type="entry name" value="TetR_C_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="194" mass="21626" checksum="D7AFE6C846F0A36B" modified="2008-01-15" version="1">MHAETLTPERILNATVDVLRRYGPNKATVVDVARELGVSHGSVYRHFASKSALLDAVAERWLAEISAPLDDVLQRQDRSVAKLRAWLECLMHTKQQRASQDPQLFATYSGLVLGLRQVTDQHVAHMIAQIERLVHEGVANAEFVVNDANATATAIWHATARFHNPLFVAAWSEPSLAAEFEAVWELMINGLLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I3</accession>
    <name>A9B0I3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4570"/>
    <dbReference type="ESTHER" id="hera2-a9b0i3">
        <property type="family name" value="abh_upf00227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07201">
        <property type="protein sequence ID" value="ABX07201"/>
        <property type="gene ID" value="Haur_4570"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4570"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090601_0_0_0"/>
    <dbReference type="OMA" id="YIYLHGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4625-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="211" mass="23945" checksum="7698DFF450042EDE" modified="2008-01-15" version="1">MRYLYSHGFASGPNSQKATWLAQQFAAHGHELLIPDLNRPSFEHLTISDQIDYLQQLITVSSEPWCLLGSSLGGLVALQAAAMIPQIERLILLAPALYFAQNRRLMLGEATLKQWQASGWLEYYNYRDHAPRAVHYGLIEDAEAYNSDNFSRNMPILIVHGTEDESVSHTQSQRFAQPRNYVTLHTPAWDHGMVGHVAELWALIESQLFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J9</accession>
    <name>A9B0J9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4586"/>
    <dbReference type="EnsemblBacteria" id="ABX07217">
        <property type="protein sequence ID" value="ABX07217"/>
        <property type="gene ID" value="Haur_4586"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4586"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_3_0"/>
    <dbReference type="OMA" id="FGCSTFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4641-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35760" checksum="6666B23C0B9CD1C0" modified="2008-01-15" version="1">MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLDTANVYGCGHSEQIIAQAIAGRRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEASLKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKIRGYGWSTDRLDAIKLFAEGPHCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDVRSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRTVAQASENAKALQFGPLNPSQMQQIASILQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0M4</accession>
    <name>A9B0M4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4611"/>
    <dbReference type="EnsemblBacteria" id="ABX07242">
        <property type="protein sequence ID" value="ABX07242"/>
        <property type="gene ID" value="Haur_4611"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4611"/>
    <dbReference type="eggNOG" id="COG3745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762419_0_0_0"/>
    <dbReference type="OMA" id="PGAQWIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4668-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="39062" checksum="708813F6A16D2BD8" modified="2008-01-15" version="1">MRQNPALGMILAVVVLIAALAGGYVYLTNQQKSQTSGDPSLLEPTNMPVPNVQILEAATDIEANKLITGADLEQYFNPLEVPPSDVTPDDVLYTEFYSVVQGKVTTTDIRGGERIKKSTFRNAGIAEKLPIPVAGEESLKAYNMFVSDIGGIVAEGNNIDILGSYSLEQPYLRFTGIDKDGIITLVDEKYLDISTHVLAQNVPVLKVVAPPLISPDGQQTGAAPPAAEPTIEVVVDGNPVEPQATPEPIFTEGSQWQIVVALTAQQAELLEYTKAKTGSKLNVVVRRADDQDDRIATTGVTMDLLMRLYGVPQVYAQPNMIVKLLDAPAPPQPPQQPAVVIPFRLPNAPQQQPLPTAVPTQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V1</accession>
    <name>A9B0V1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imm40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1173"/>
    <dbReference type="EnsemblBacteria" id="ABX03821">
        <property type="protein sequence ID" value="ABX03821"/>
        <property type="gene ID" value="Haur_1173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1173"/>
    <dbReference type="eggNOG" id="ENOG502ZIT8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168172_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1195-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029080">
        <property type="entry name" value="Imm40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15569">
        <property type="entry name" value="Imm40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Imm40" evidence="1">
        <location>
            <begin position="18"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13425" checksum="0F224162B11BAD79" modified="2008-01-15" version="1">MLKNRAAYNAFLSQKGILLSELGTQEYALDQQDAMNAIVIIEDLAIPILGGDVYLQSLEGIEISYENWSINRQPGESLDNYVRRSCAYTRNYIARFPVQAEKLPLFVLVLASDLQMLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V2</accession>
    <name>A9B0V2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine--fructose-6-phosphate transaminase (Isomerizing)</fullName>
            <ecNumber evidence="3">2.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1174"/>
    <dbReference type="EnsemblBacteria" id="ABX03822">
        <property type="protein sequence ID" value="ABX03822"/>
        <property type="gene ID" value="Haur_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1174"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_2_1_0"/>
    <dbReference type="OMA" id="QSFYVMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1196-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="32"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="198"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="348" mass="37813" checksum="D70F38E383C87E26" modified="2008-01-15" version="1">MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQYLLGSLNGILVTLATPSLFSIYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTAAITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAAIALLSTALADDSAMNQALERLPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSSADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTSLRTPAGLPEWLSPIINIVPGQLLALHLAHTRDFDVDQPRGLRKVTETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y8</accession>
    <name>A9B0Y8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carbamoyl-phosphate synthase L chain ATP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2628</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2628"/>
    <dbReference type="EnsemblBacteria" id="ABX05266">
        <property type="protein sequence ID" value="ABX05266"/>
        <property type="gene ID" value="Haur_2628"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2628"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_0"/>
    <dbReference type="OMA" id="TRWIESD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2656-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="3"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="122"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="565"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="653" mass="70814" checksum="05624C32E7F3B4D6" modified="2008-01-15" version="1">MTYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQSYLNIEAVLAAAQQTGAQAIHPGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSAAKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIKASAGGGGKGMRSVHRLAEFSAALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKVLEESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHPVTELVTGLDLVQLQIAIAAGQRLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYTPPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQAIARLRYALQHFEVAGVTTNIPLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVGDPWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVVRVADRIYQCQLEQDSLVWQGVGYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAEGEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQVSGGVALAEITAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B103</accession>
    <name>A9B103_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2643"/>
    <dbReference type="EnsemblBacteria" id="ABX05281">
        <property type="protein sequence ID" value="ABX05281"/>
        <property type="gene ID" value="Haur_2643"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2643"/>
    <dbReference type="HOGENOM" id="CLU_1233654_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2673-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="26455" checksum="DC07B93274D9030F" modified="2008-01-15" version="1">MDSFEPLRAAGLDVTFHVWDEEEVATAIRYAQQRRSQGLPSQVPYFWYANVSKPADHPTYNLSQDVTQEKTPRPLDSLVSSIALQIENRQACYWKIWDYIPGPVHHEFFCHYESLDMLIPNLINYYCGESTIINDWVVPLNRHPELNPRRVATIIVHARPTTLTKLEKHQTNQSHRDQMQWNRERCTRHAFLRQYLIIKHNSDPTSQLYLRRDCRAAWIIPQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E1</accession>
    <name>A9B1E1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycyl-tRNA synthetase</fullName>
            <shortName evidence="7">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyQS</name>
        <name evidence="9" type="ordered locus">Haur_4697</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glycine to tRNA(Gly).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4697"/>
    <dbReference type="EnsemblBacteria" id="ABX07328">
        <property type="protein sequence ID" value="ABX07328"/>
        <property type="gene ID" value="Haur_4697"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4697"/>
    <dbReference type="eggNOG" id="COG0423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_2_1_0"/>
    <dbReference type="OMA" id="EPSYGID"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00253_B">
        <property type="entry name" value="Gly_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022961">
        <property type="entry name" value="Gly_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="7"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="192"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="316"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="261"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="320"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="459" mass="51740" checksum="82B6DEC26DDC0502" modified="2008-01-15" version="1">MPATSMDELVSLCKRRGFIFPGSDIYGGLQGTYDYGPLGIELKNNLKAAWWRAMVYERDDVEGLDASILTHRLVLRHSGHEATFTDPMVDCRNCKSRWRADQLKDNKCEKCGSTDLTEPRPFNLMFKTAVGPIAEEGSFAYLRPETAQGIFTNFKNVVDATSRRLPFGIAQIGKAFRNEITPRNFIFRVREFEQMELEFFVQPGTDDEWHSQWVEARLQWWRDQGLLSENLQAYHQAGDELAHYAKATVDILYQFPHGLEELEGIANRTDFDLGSHTRGQADLGLSAKVDPNEDSTAKLTIPHPETQKPLVPFVIEPSAGVDRGVLAILTEAFTKETLENGSERIVLKLKPHLAPIKVAVLPLARNKPEIVEKAKAIKSLLMATGIGRIFYEDTGNIGKGYRRHDEVGTPFCVTVDFDTLGRGDDASLLDTVTVRDRDTMSQVRIHINELASYIRERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J1</accession>
    <name>A9B1J1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenide, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenium donor protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selD</name>
        <name evidence="8" type="ordered locus">Haur_1228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Synthesizes selenophosphate from selenide and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate</text>
            <dbReference type="Rhea" id="RHEA:18737"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:29317"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the selenophosphate synthase 1 family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1228"/>
    <dbReference type="EnsemblBacteria" id="ABX03876">
        <property type="protein sequence ID" value="ABX03876"/>
        <property type="gene ID" value="Haur_1228"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1228"/>
    <dbReference type="eggNOG" id="COG0709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032859_0_1_0"/>
    <dbReference type="OMA" id="DNEPKYG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00625">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023061">
        <property type="entry name" value="SelD_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="PTHR10256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="29"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="147"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="27"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="34104" checksum="42BB40048A80E68B" modified="2008-01-15" version="1">MGAGALSNLISSLRLPSSPQLLVGLDVSDDAAVYQLNQQQALVQTVDFFPPIVDDPYSFGAIAAANALSDVYAMGGKPILALAIAGFPRDLDPAIIQAIMQGGADKVAEAGAVLAGGHTIIDNEPKYGLCVTGLIDPALITRKAQAQPGDQLYLTKALGTGVISTASKRQIADPADLAAAIESMLKLNRHAAEHIAMLGTIRSATDITGFGLLGHGLELARNSGVGLQINSRALPLLSGAYRYAKAGIMPGGLHTNRAYVEQQMQVNYAKTVDPVHQALLYDPQTSGGLLIAVAAEHAKALEQQFAQAGDPLWSIGTVIELQALEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K1</accession>
    <name>A9B1K1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1238"/>
    <dbReference type="EnsemblBacteria" id="ABX03886">
        <property type="protein sequence ID" value="ABX03886"/>
        <property type="gene ID" value="Haur_1238"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1238"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080384_2_0_0"/>
    <dbReference type="OMA" id="AFCIWPQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1260-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="22960" checksum="8489E7B81DB87B40" modified="2008-01-15" version="1">MVDQFLRQPKEQLLAPIAQRLQRVHPTTITLAAFGCGLAAAICAWQQAYWVSFGCWLLNRLLDGLDGTVARLSNQQSDLGGYIDILLDVIIYALLPIGLVAGQPTLGNALAAVGLISSFYVNAISWAYLAAILEKRQQGAKAQAAMTSIAMPSGLIEGTETVLFFSLFIALPNHLSRLFQLMTALVVVTIGQRLLWAKRYLREEPRHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B225</accession>
    <name>A9B225_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4744"/>
    <dbReference type="EnsemblBacteria" id="ABX07375">
        <property type="protein sequence ID" value="ABX07375"/>
        <property type="gene ID" value="Haur_4744"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4744"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_992682_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4802-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29921" checksum="ECCBCAB7F05F08FE" modified="2008-01-15" version="1">MTTYTWLGHDRPHLDTLFVQDLGAMVFASFGGVVAQGARKNEDAAAIFIDPAGGWELAVVIDAHHSAQSALLILETLVGAETQLRECLNQPLNQAFFSLDQALLDIFRSNRFRARCAAIQGEASCLFVARKDEYVWYWAVGDCIGYIFHPSIARLGEMQLNQRRFYEWIGNVNTWDGVLPSYSTGIRLLQPGLTTIMLTTDGLLECGTRPFENPTTLYNAVCWEQHSLPRAARALLERVQTEGGRDSATAILWQFDSTWAGINRDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B230</accession>
    <name>A9B230_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4749"/>
    <dbReference type="EnsemblBacteria" id="ABX07380">
        <property type="protein sequence ID" value="ABX07380"/>
        <property type="gene ID" value="Haur_4749"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4749"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_31_0_0"/>
    <dbReference type="OMA" id="EITYWID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4807-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17809" checksum="EDE4D0AC87D75045" modified="2008-01-15" version="1">MPELSLRPIEAADLASFFEHQQDPLAIHMAAFTAKDPSDYAAFQAHWHKIMADDRIIKRSIIWDQQLIGHIAQFEQFGEPELTYWLDRAYWGRGLASQALELLLNEIATRPLFARVVQDNHGSLRVLTKAGFQIIGQDTGFANGRGCDVAEYVLRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B1</accession>
    <name>A9B2B1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1308"/>
    <dbReference type="EnsemblBacteria" id="ABX03956">
        <property type="protein sequence ID" value="ABX03956"/>
        <property type="gene ID" value="Haur_1308"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1308"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_12_0"/>
    <dbReference type="OMA" id="HGGFAQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1330-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="30"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="286"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="42522" checksum="19DB05C0F4DBCE71" modified="2008-01-15" version="1">MSNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQTTHYLAAAYHLPPVLCHPQALEDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVRFHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGDLLSMAIERTRLFERSLSLGAVEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEARRSVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALNNVRQHAQANAVVIEYHATPTQIEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLEIKSTLGAGTEVCIVVPLGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M4</accession>
    <name>A9B2M4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2837"/>
    <dbReference type="EnsemblBacteria" id="ABX05475">
        <property type="protein sequence ID" value="ABX05475"/>
        <property type="gene ID" value="Haur_2837"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2837"/>
    <dbReference type="eggNOG" id="ENOG5033BSP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192036_0_0_0"/>
    <dbReference type="OMA" id="CARAWWL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2868-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8841" checksum="D0F591D8F97178EF" modified="2008-01-15" version="1">MAERKPIIRASELGEYDFCARAWWLRRECGWEGRFPERLAQGEAAHQRYGQDLQQSQWLRTVAIGLLVLAALALVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W2</accession>
    <name>A9B2W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3389</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3389"/>
    <dbReference type="EnsemblBacteria" id="ABX06025">
        <property type="protein sequence ID" value="ABX06025"/>
        <property type="gene ID" value="Haur_3389"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3389"/>
    <dbReference type="eggNOG" id="COG3075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047793_1_0_0"/>
    <dbReference type="OMA" id="CFGLENQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3426-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009158">
        <property type="entry name" value="G3P_DH_GlpB_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000141">
        <property type="entry name" value="Anaerobic_G3P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03378">
        <property type="entry name" value="glycerol3P_GlpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="4"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="44462" checksum="33D1A218220C1442" modified="2008-01-15" version="1">MQADVLVIGAGLAGLWSAIIHAQAGRKVSLLAKGHGTLPWSSGCLDLQPHQLPTNREHPYFTLQTVLEPTTQTWLKFTQAQDYRFVANLKQHYWLPTAIGTWRPTNAVPLTMLNAERSIISNYRVLVLGFRELRDFFPPLLAARLQQHGIAARGSYLTMPTSQRSRDFNSVNLARLCEQTSFRQALIKQIDQIRGDAQLLLFPAMLGISHTTSIINELQTALGCLVAEVPTLPTNVAGLRLQRMLMTELEQLNGRIQLNAEVIRGEFIDRRLVAVYSAAAAREQRHTAEHFILATGGIGGGGLRADYPNGLRETALNLPVQQPTERDQWFEANVHAQHQLFKAGIAVNQQLQPIDAQQQPIAENLQVVGAALAGCDPIRERWVEGLALASASHAFENRGFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B352</accession>
    <name>A9B352_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutamyl aminopeptidase</fullName>
            <ecNumber evidence="9">3.4.11.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.7" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4885"/>
    <dbReference type="EnsemblBacteria" id="ABX07515">
        <property type="protein sequence ID" value="ABX07515"/>
        <property type="gene ID" value="Haur_4885"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4885"/>
    <dbReference type="eggNOG" id="COG1363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047249_0_2_0"/>
    <dbReference type="OMA" id="FGWPAIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4945-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="360" mass="38129" checksum="A0B68CF8DE384B5F" modified="2008-01-15" version="1">MDERLALMKALTDASGVPGNEGPVRAVMAEALAPYGELINDQLGSVAARKAGPEGSPTILLAGHLDEVGFMVTRITDDGFIKFQALGGWWELVMLAQRVQIETRNGPIAGLIGSKPPHVLSPEARKKLVEKKDMFIDIGASSAAEAREWGVRPGDSILPVCPFTPLHNPKIVMAKAWDNRFGCAAAVEVLHELANESLPNTVVAGATVQEEVGLRGAATLANVVKPDIAFAIDVCIAGDTPGISKDEAQAKMGAGPVLLLMDSSVIPNPRLRDLVVDTAEELGIPYQFDTMPGGGTDAGRFHLNNAGVPSLALGVATRYIHTHASLLHRDDFDQVVTLLAAVVRKLDQATVDYIKTGQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B358</accession>
    <name>A9B358_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease MutS2</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS2</name>
        <name evidence="10" type="ordered locus">Haur_4891</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4891"/>
    <dbReference type="EnsemblBacteria" id="ABX07521">
        <property type="protein sequence ID" value="ABX07521"/>
        <property type="gene ID" value="Haur_4891"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4891"/>
    <dbReference type="eggNOG" id="COG1193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011252_2_1_0"/>
    <dbReference type="OMA" id="IHAIIND"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03280">
        <property type="entry name" value="ABC_MutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00092">
        <property type="entry name" value="MutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF14">
        <property type="entry name" value="PTHR11361:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005814">
        <property type="entry name" value="MutS_YshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01069">
        <property type="entry name" value="mutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="9">
        <location>
            <begin position="729"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="544"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="342"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="806" mass="88808" checksum="12E0C70651C64563" modified="2008-01-15" version="1">MISEVVLQTLEFDKVRDQLARHAAFSASRELVAQLHPSTDGQWILQAQIRTSAARALIESFADVSIGGARDVRPAVEHARRGGILEASRVQEIAATLGAMRRLRGQVLRNHPDFVPLHPLAEQLPNLATLEHEIERTIGPDGEVLDSASAELGRLRSAIRVAFNRLQERLQAIINSSQYADVLQEPIITVRDGRYVVPVKAPQRRALRGIVHDQSSSGATLYIEPLATVELNNQWRELQLAEREEIQRILAALSGKIANEGMPIIVGVEATAELDLAFAKAKYSISLRASQPAINTPVPADDLHPESTLSLLKARHPLLNQDLVVPTDVWLGGPTQMIIITGPNTGGKTVALKTVGLMALMAQAGLHIPAHQGSRLPIFGKIFADIGDEQSIEQSLSTFSSHMTNIIQILDRVTPDSLVLFDELGAGTDPVEGAALARAIIERLLNVGCLAMATSHYAELKAFAYSTDGVENASVEFDVETLSPTYRLSIGLPGRSNALAIAERLGLKRDLIERARATISRDNVQVEDLLAAIHRERTTAESEAARALELREDAELVRDRLSRELYEFEQDREQQLASYQRQLDDELREVRAELRRLRDEFRSVSVSRQWMEQAEQRLSRVAERVPQTPTPPKAKVPVVPKVALAPLPRTIQVGDQVFVSSVKLSGVVLDLDEEANEAEVQLGGFRLRVDLRELRLEKAGTSPTQAVQKYVPVQRMINTPPPPNVSMQLDMRGWRASDVESQLDHYLNDAYLANLSEVRLVHGKGTGALRQVVRTLLKRHPLVESYNSGSQGDGGDGVTIAKMVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B375</accession>
    <name>A9B375_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4908"/>
    <dbReference type="EnsemblBacteria" id="ABX07538">
        <property type="protein sequence ID" value="ABX07538"/>
        <property type="gene ID" value="Haur_4908"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4908"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="WTATAEL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4969-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14286" checksum="E9BB2CD696373A42" modified="2008-01-15" version="1">MGMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDGWTATAELKAQSRYSHIPVIAVTGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLKKNEKQLALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3D9</accession>
    <name>A9B3D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1458"/>
    <dbReference type="EnsemblBacteria" id="ABX04102">
        <property type="protein sequence ID" value="ABX04102"/>
        <property type="gene ID" value="Haur_1458"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1458"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_4_0_0"/>
    <dbReference type="OMA" id="ICCANSA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1480-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="251"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1271" mass="142667" checksum="AC11BF5B21F4B456" modified="2008-01-15" version="1">MQARWFAYVPPYLVPRLLDQRASSATQTTKHGQAVVLFADIAGFTPLSEALGQHDSHGTETLTRLLNRCFAPLIDVIERFGGMISTFGGDAITALFPINQPQRTQRVAARAVRCALEMQSLMEQLGAIEIQATKWRLTLKIGIAAGHVLYTTVGDPTKRCVAVVGGSALLRSAEAENQARSGDVIIDYASLDCEQFKRETLDQRFAKVLGLEQSVRAQPIRWPEPITPHPPAQFDAYLHPTIAQQVREGRTAFINERRSVTLLFVNFDAPDYDRDPFAAERLNHYFREVLRIVERYDGYLNKVEIGDKGSSFLVLFGAPVAHENDSDRAAHCALELRALPEFEARIGINTGFVFCGLIGSERRQEYTVIGDTVNLAARLMQQAGQGQILLTEATQETLSSTFLTAPLPAVRVKGRSELVELHELTDLRQTAIRGQEPIYALPMVGRSQELQSVGELLSRIKQGHGQVLGITGEAGMGKSRLVAEIRRIARAQRVAVYSGECLSYGTTISYLLWHNLWRSFFNVDPEWPLDLQMLQLRAQLALIDQDLLDWMPLLASALRLPIPDQSLTKLLDIKSRKMLLESLLVDCLRYRANETPLLLVLEDCHWIDSLSNDLLARITKAIRDVPVLIVLAYRPSAERDQTMWHELRQLEHWHEIELQEFTLDETAELVRLKIKQLLGNRQAPSEQLVSKLTDRAQGNPFYIEELINLVVERQPDLSDPKAVAQLELPDSLHRLIISRIDQLEEATKHTLKVASVIGRLFKANWLWGAYPQLGSAEQVKQQLNTLSRMDLTPLDRDEPELEYLFKHVVTQEVAYQSLPLATRAALHEQVGDYLVETYGVEGAADLLAHHYGMSNNLDKQRNYFRKAGDAAAARYATDVALSYYERCLPLLAAHETIDIFFAMGEIYKHTGRWHEADAIYRRLLNQAQQQQQLSALARVWCEIADVQSSQGLHNDALQSIQPALEYAKQAHDQPTHCKILMRMSWIASYQGQLQQAWQTSHAAVAIAREANDAHSLALALKTHGYMNVLQGQFALAEQLFSEGLALHRQLGQREDEGRMLNVMGEAARHRGDFQHAVELYQQALVIGRELRNPERLIMFLSNLGGALVGLGTYETAIATLNEAFELARSTTWYGIAETYRFRAEAAIGLGYPDEAIRHIIQAHHAARERQQTLELCAALRVLGSALSQLNVPILLPPSLPTTPLNCFEQALSMAEASGSQAEVAAIQLALAEHWQRQQQPTKAQAAWQQAYTIYGQLGMDALQQRVAQWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K4</accession>
    <name>A9B3K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2938"/>
    <dbReference type="EnsemblBacteria" id="ABX05576">
        <property type="protein sequence ID" value="ABX05576"/>
        <property type="gene ID" value="Haur_2938"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2938"/>
    <dbReference type="eggNOG" id="COG4420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077948_2_3_0"/>
    <dbReference type="OMA" id="DPYPYIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2970-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41386">
        <property type="entry name" value="PTHR41386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20383" checksum="CB389106D46267F0" modified="2008-01-15" version="1">MANQTPQHDHSHQLSALAARERELIKHLIEHPTISKNTNHQFEADQTFGERLADRVAAFGGSWPFLIGFSSALLGWMLLNGLFLTKPFDPYPFILLNLVLSSVAALQAPIIMMSQSRQAAKDRLDASNDYEINLKAELEIQRLHNKIDDLREAQWHELVQLQQEQIRLLNQILSQRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L0</accession>
    <name>A9B3L0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2944"/>
    <dbReference type="EnsemblBacteria" id="ABX05582">
        <property type="protein sequence ID" value="ABX05582"/>
        <property type="gene ID" value="Haur_2944"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2944"/>
    <dbReference type="eggNOG" id="COG1830">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057069_0_0_0"/>
    <dbReference type="OMA" id="FVKVNYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2976-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="38369" checksum="67B0B445F55A2227" modified="2008-01-15" version="1">MIDRIAELLGDEASSLLEHQSKTISKDLIHQPGPDFVDRVWTASDRSIPVLRNLQSLYGTGRLANTGYLSILPVDQGIEHSAGASFAPNPAYFDPENIVKLAIEGGCNAVASTFGVLGSVARKYAHKIPFVVKINHNEFLSYPNKFDQILFGTIKEAHEMGAAAVGATIYFGSAESGRQIVEVAQAFKMAHELGMATILWCYLRNNAFKNSTTDFHVSADLTGQANHLGVTIEADIIKQKLPENNGGYNAVTSKDNPYGKTDKRIYSELTSDHPIDLVRYQVANCYMGRASLINSGGASSGESDTAEAVRTAVINKRGGGAGLISGRKAFQRPMAEGAALLQAIQDVYLCEDVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N0</accession>
    <name>A9B3N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2964"/>
    <dbReference type="EnsemblBacteria" id="ABX05602">
        <property type="protein sequence ID" value="ABX05602"/>
        <property type="gene ID" value="Haur_2964"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2964"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1560836_0_0_0"/>
    <dbReference type="OMA" id="AVNECPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2996-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19027" checksum="0E79B78AB139DFC1" modified="2008-01-15" version="1">MTSNQTALLLETAVAALYAGDRRSARVYLTQALALEPYNEIALLWLSGAVELPEQQIACLERVLAINPYNHAAIRGLASLRGPLEPMVVEPEPLPPWNPPEPLSLSQLAELPVCCYACDAQLYASATFCWRCHVHVRCCANCIFNGYVECKTEQAIQSEQLPNCCPWWRPI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3S3</accession>
    <name>MINE_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">minE</name>
        <name type="ordered locus">Haur_3423</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MinE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B3S3"/>
    <dbReference type="SMR" id="A9B3S3"/>
    <dbReference type="STRING" id="316274.Haur_3423"/>
    <dbReference type="EnsemblBacteria" id="ABX06059">
        <property type="protein sequence ID" value="ABX06059"/>
        <property type="gene ID" value="Haur_3423"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3423"/>
    <dbReference type="eggNOG" id="COG0851">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137929_1_1_0"/>
    <dbReference type="OMA" id="IRREMCE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114226" description="Cell division topological specificity factor">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <sequence length="87" mass="9915" checksum="EE35103FB89389BF" modified="2008-01-15" version="1">MGLLDNLFGRKQQNSSSVAKERLLTVLVHDRVHLTPHDMEEMKREIIAVIERYVEVTNPEAIEVTLTRGEAADHLKADIPLGRSRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T6</accession>
    <name>A9B3T6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Gluconokinase</fullName>
            <ecNumber evidence="4 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3436</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3436"/>
    <dbReference type="EnsemblBacteria" id="ABX06072">
        <property type="protein sequence ID" value="ABX06072"/>
        <property type="gene ID" value="Haur_3436"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3436"/>
    <dbReference type="eggNOG" id="COG3265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077168_1_0_0"/>
    <dbReference type="OMA" id="ENFIQVS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3473-MON"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="PTHR43442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18263" checksum="865721261D02CA9A" modified="2008-01-15" version="1">MVIVVMGVSGVGKTTVGQLLATAQAWQFIDADDLHPEANRQKMANGQPLTDADRWPWLALVREQISAVLAQNCSLVLACSALRAEYRDYLAVDQQVHFVHLVGDPALIQARLQQRSNHFMPSSLLASQLATLEMPSNALTLTVDAEPKTLVESIQRWMLDLTTPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X1</accession>
    <name>A9B3X1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3471"/>
    <dbReference type="EnsemblBacteria" id="ABX06107">
        <property type="protein sequence ID" value="ABX06107"/>
        <property type="gene ID" value="Haur_3471"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3471"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049749_5_2_0"/>
    <dbReference type="OMA" id="TNMHSEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3508-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="42"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="23537" checksum="6BBB78B2121E07FB" modified="2008-01-15" version="1">MSIQQAYNQWASSYDNDRNRTRDLDQQVMQQLLQGHHYQAILELGCGTGKNTQFFSTIGTAVVALDFSSGMLEQARSKINAQHVQFQQADLTKAWPVARAYFDLVVTNLVLEHLADLDHFFAQANQALMPNGQLLISELHPFRQYQGSQARFQGQHGQIEVPAFTHHISDFGRAATKHGLQLSQLHEYWHADDANQAPRLLTLSWHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X4</accession>
    <name>A9B3X4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ordered locus">Haur_3474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3474"/>
    <dbReference type="EnsemblBacteria" id="ABX06110">
        <property type="protein sequence ID" value="ABX06110"/>
        <property type="gene ID" value="Haur_3474"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3474"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_4_2_0"/>
    <dbReference type="OMA" id="LCTMRAI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="19972" checksum="6D68A2D76DECEFF7" modified="2008-01-15" version="1">MAVVPLIELGNPLLRQPATPFADPTSPEVARILNDMRDTLADMRQRIGYGRGIAAPQIGVLKRLILIDTPDTNLVLVNPRFERWSREEDERYESCFSFPGIWGLVQRPLGVTVVAYTLAGEEQRIEASGSLSRIIQHEMDHLDGFVWLDRGPDLHSLCTTQEYEKRYISRERESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z5</accession>
    <name>A9B3Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3495"/>
    <dbReference type="EnsemblBacteria" id="ABX06131">
        <property type="protein sequence ID" value="ABX06131"/>
        <property type="gene ID" value="Haur_3495"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3495"/>
    <dbReference type="eggNOG" id="ENOG5030T5P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_887881_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3532-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="36844" checksum="D1D59D3C98BFDBDE" modified="2008-01-15" version="1">MRLLLGILLLNLVWCSYRPQERQILWGWFLRIWPRVRPILGWFLIFIGILGVILPILQGIIFLVIGSALIGPRHRLIRRTRVAYKQVLHRLAGSSNRFLAWLGRFGISSLRTMNQQIRRFMEYRTRYQRKHRPIRLAIVPPPDVVAMLDHYRQRYDPSYRHGLPPHIVLVPSSHPSDRDDFERAVATTLSQWSSFDLTLEHLQIAPNQHRLVLLPSQGKNLLEQLQASLPQTRPIKRQPWPALTIGKLLQYSSLASAQTWVAETWQPQRWHVAELVLFEERFGRMWHEVRRFRLGARTNHAECVKIHALNDYA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B427</accession>
    <name>RL18_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplR</name>
        <name type="ordered locus">Haur_4930</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B427"/>
    <dbReference type="SMR" id="A9B427"/>
    <dbReference type="STRING" id="316274.Haur_4930"/>
    <dbReference type="PRIDE" id="A9B427"/>
    <dbReference type="EnsemblBacteria" id="ABX07560">
        <property type="protein sequence ID" value="ABX07560"/>
        <property type="gene ID" value="Haur_4930"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4930"/>
    <dbReference type="eggNOG" id="COG0256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098841_0_1_0"/>
    <dbReference type="OMA" id="NKQIYAQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142677" description="50S ribosomal protein L18">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <sequence length="121" mass="13373" checksum="8C18E134287CFFE7" modified="2008-01-15" version="1">MSKFTSRELRARRHRRLRGQLSGTPERPRLNVFRSGLNIYAQVIDDLAGHTLVSASTIDTELRGSLGEQRKLEQAHSVGKAVAERARAAGITKVVFDRGGYKYHGRVKAVAEGAREGGLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B470</accession>
    <name>A9B470_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclease A inhibitor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4973"/>
    <dbReference type="EnsemblBacteria" id="ABX07603">
        <property type="protein sequence ID" value="ABX07603"/>
        <property type="gene ID" value="Haur_4973"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4973"/>
    <dbReference type="eggNOG" id="ENOG5032BV3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145415_1_0_0"/>
    <dbReference type="OMA" id="QDWYEDE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5036-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012489">
        <property type="entry name" value="NucleaseA_inhib-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036587">
        <property type="entry name" value="NucleaseA_inhib-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07924">
        <property type="entry name" value="NuiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82602">
        <property type="entry name" value="SSF82602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="15973" checksum="20CD4A6AC893191C" modified="2008-01-15" version="1">MPFRRPRRGRISPIRRKQGVSVAETSVEKITAAANGLLMMSETDAPFTPFAWDAATPFSPEALANGQPIQTISLEQFLGNATTVQEWHGEAEKATVSQFQQLVEVLKAELTDIQVYRVGEINIDAYIVGKDSAGNLVGLKTQLVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D0</accession>
    <name>A9B4D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal-transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0035"/>
    <dbReference type="EnsemblBacteria" id="ABX02687">
        <property type="protein sequence ID" value="ABX02687"/>
        <property type="gene ID" value="Haur_0035"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0035"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040681_9_3_0"/>
    <dbReference type="OMA" id="GIHHLYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-35-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="11"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15092" checksum="CDB2E4DD0D92E43D" modified="2008-01-15" version="1">MTAQLTVGDTMNAEVISCRTETSLREAITLLQGNRIQALVVVDGPGSLAGVFSQTDALGAWSRGLDYERSMDSPVGEFMTRDVITCMPHVDLSRAANLLTSNRIHRLVVVEERNDGRVWPIGVLSQTDIVRKLGEEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I5</accession>
    <name>A9B4I5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1506"/>
    <dbReference type="EnsemblBacteria" id="ABX04150">
        <property type="protein sequence ID" value="ABX04150"/>
        <property type="gene ID" value="Haur_1506"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1506"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_2_0_0"/>
    <dbReference type="OMA" id="SDWVSNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1528-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="807"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="595"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="876" mass="97502" checksum="96C3951FC7B09742" modified="2008-01-15" version="1">MPIPILATKLHIPQLRPNGVMRSHLIQRLDAASHASLNLISAPAGFGKSSLLSAWHATSQRPMAWLALDERDNDPSRFFSYFVHALQTLIPTLSSASLRLIHTQPPAIEQALTNLINELSVVGSSVSLVLDDYHVIENHAIDQALSFLLEHLPASLRLIIATREDPNLPLARLRARGQLHELRSADLRFSLDEAQLFLNQAMGLALSPADVAALENRTEGWIAGLQLAALSMQQQTDRSRFIASFSGSHHFVMDYLLEEVLQQQTPAVQQFLLQTSILNRMCGSLCDALVSNGTNSGQQMLEQLEQANMFIVPLDHERRWYRYHHLFGELLRQRLQRSLAQQATTSLEQLHIQASIWFEANELELEAFEHAAAANDTERAERLIEGKRVPLQFQGALLPIMAWLQALPTNVLNQRPSLWVTAAAVWLATGQVNGIEQRLQAAEQAIDQHPLTPKLHDLIGRIAAIRGTLALSQNDASQIIAQSKRALEYLAIDNLSFRTSTVWKLGYAYQLQGKRSAAKQAYEQAISIGQRSGNLVTVVLASIGLGNLQESNNQLKLAATTYQQVLEASRQLALPAANCGAELGLARIYYQWNQLDQAEQHYQRALQAAQLLQHTDREVACYVIKARLLIAQNQLDQASLLLEQASAAAHQHRHTTQPAKIAAEQVRIGLMRGQVQQASQIAQTHQIPISQAQVFLAQQQPSAALALLQPALTIAQTNSWHDQSLWIKVLQSLALAALEDYAQAQQVLKPSLISAEPEGFVRVFLDQGQAIQNLLSHINLTTSSKNYVNQILAHFTTERMPQLYPTTPSLPEMLSQRELEILSLIAQGHSNQAICQQLHLALDTVKGHNRRIFEKLQVQRRTEAVARARELGLLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T8</accession>
    <name>A9B4T8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ordered locus">Haur_3023</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3023"/>
    <dbReference type="EnsemblBacteria" id="ABX05661">
        <property type="protein sequence ID" value="ABX05661"/>
        <property type="gene ID" value="Haur_3023"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3023"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_2_0_0"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3055-MON"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="8"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="240" mass="26366" checksum="2C0055C96E4C2DEB" modified="2008-01-15" version="1">MTLQIAPSREELMILAADRLVAEAQTAIAQRGRWTIALSGGSTPKALFELLASPRYINQILWGRCFLFWGDERCVGPDDLQSNYRMTKIALIDHIPIPVGNVLRIRGELAPESAASLYAHEIKRIFGLAEGQFPQFDTMLLGLGNDGHTASLFPASDILGRNDVLVAETWVAKLKQYRISLTAPVINNAHSKIFLAAGDDKAGVIRELIEQTGAYQSYPASLINNADWLIDQAAASQLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B575</accession>
    <name>A9B575_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3576"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06212">
        <property type="protein sequence ID" value="ABX06212"/>
        <property type="gene ID" value="Haur_3576"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3576"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_14_2_0"/>
    <dbReference type="OMA" id="KDIWTSP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3615-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="107"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="213"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="415" mass="46300" checksum="D0357FAAD64E66FE" modified="2008-01-15" version="1">MAQPIAYMMSRFPHLSETFILREMLEMERLGWDVKLFPLMLQQQAVVHDEAKRWIPLAQPQPFISPHVALSSLQRLAKQPLKTGGIVAKTLAESATTPSELVRKLALIPKAITLAKHMQAQQIAHIHCHYATYPAFAAWIINRLTGIPYSFTVHGHDIFVNRAMLPTKARGASAIMAIAEFHREFLVEKLGEWVRDRIHIVHCGIRPERYQPQPKPAGERFEILTTGSLQDYKGHPFLIQACSFLRDRGIAFRCRIIGGGEDRPMLEQLIAEKQLTGMVELLGPQPETAVRELLATADCYVQASIITPSGKMEGIPVSLMEALACELPVVASRMSGIPELVRHGETGYLVPPANAAALAEQLLYVRDHPEEAASYAARGRELVQRDFNLVTCVEKLSETLLAVNPALQRPIQRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K1</accession>
    <name>A9B5K1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1591"/>
    <dbReference type="EnsemblBacteria" id="ABX04234">
        <property type="protein sequence ID" value="ABX04234"/>
        <property type="gene ID" value="Haur_1591"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1591"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_1_0"/>
    <dbReference type="OMA" id="PRAWLMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1615-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="40"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="135"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="23339" checksum="EC1EC6E8345A217C" modified="2008-01-15" version="1">MTWNQFDRSGVEPSEATQSGAAVEQAPHADLAQAWATHILAHQTAIFRLAYLMVGDAMIAEDLAQETLMRALRMQHRFDQARPLKPWLLQITANLARNYRRSLRRYLRALQRFATQQPEFSEFSETSGPAWEATQLWQAISRLAQREQEVIYLRYFLELSEQETAQALGIAQGTVKSRLHRALVRLRGVIDGEFPELRTERCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K5</accession>
    <name>A9B5K5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1595"/>
    <dbReference type="EnsemblBacteria" id="ABX04238">
        <property type="protein sequence ID" value="ABX04238"/>
        <property type="gene ID" value="Haur_1595"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1595"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533981_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1619-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="348"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="510" mass="58254" checksum="789F94A7FE62A88E" modified="2008-01-15" version="1">MVFVPLLLPQSTAARIILAEDRAFDQLWQNTDGQRGDEQSWLWGPQRLWQTQERYAESPRELRWVRYYAKARMEISDPKLSAKSPWYITNGLLVVELVTGRLQIGNAAWREQCTDGICGSEQAVAGDAVAANRAPRYRDWAEFLTLNGQTGADLRGQPVTNWLTHEAEGLQVWSDPSLAERYPETSGNHRDEVTGQTVPAVLWEYVQAQAREALYVFGRPISPAFWTQTLVDGIEREVLVQLFERRTLTYTPSNPLGWQVEMGNVGQHALEWRYDLRPWDYQPLHVTMLTYHYISANPNPADRLRESLSVAPAEFKRQLEYLQNHNFHVVSLDQVLAAQRGELSLPEHPVVITLDDGYRDLYEQAFPIAQSLNLPITAYIPSALVGEPAYVSWQQLQELSQSPLVTIGSHTRIHADLGTLDRESQWIEIADSKRELEAHLGIAIEHFCYPYGRYNALTMELVREAGYRSATTTRQTTDTANDDPLIWNRITISGRDSFEDFVAKLERSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5L6</accession>
    <name>A9B5L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1606</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1606"/>
    <dbReference type="EnsemblBacteria" id="ABX04249">
        <property type="protein sequence ID" value="ABX04249"/>
        <property type="gene ID" value="Haur_1606"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1606"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_0"/>
    <dbReference type="OMA" id="RKEWYAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1630-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="105"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38311" checksum="BA83DF662B3A8129" modified="2008-01-15" version="1">MVGYIFRRLLGIIPVLLGISLLVFTLLRTIPGDPAIIILGERSTPEQRAALRTKLKLDRPLFLNFEGGNIFESQYVTYITNFATGDFGDSIKTRQAISKELKQRFPATIELALSALLIAVVVGVTTGVVSATKRGSWLDASSMIVALLGVSIPIFWLGLMMQYLFSVKLKWLDPSLRLDTSLQGSFEPITGLYLLDGLLLGRFDITMNAFKHLIMPSLALATVPLASIARMTRSAMLEVLYQDYIRTARAKGLSARITILRHGLRNALIPVITVIGLQLGFLLGGAVLTETVFSWPGIGRWLLDGILARDYPVVQSGVMFVSLVFVLINTLVDISYRFFDPRIQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q2</accession>
    <name>A9B5Q2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1642"/>
    <dbReference type="EnsemblBacteria" id="ABX04285">
        <property type="protein sequence ID" value="ABX04285"/>
        <property type="gene ID" value="Haur_1642"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1642"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_13_3_0"/>
    <dbReference type="OMA" id="IEFRMHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1666-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="15"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="103" mass="11624" checksum="EC9E6EBB544CF713" modified="2008-01-15" version="1">MINELSVQELQVWANQQTIFLIDVREPAEYATGHIKGSNLMPLSQLNNYRNQIPHDLPVVVVCRSGQRSSMAAQWLASNGWNNIYNTRGGMLAWSKAGLPEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S1</accession>
    <name>A9B5S1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RarD protein, DMT superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1661"/>
    <dbReference type="EnsemblBacteria" id="ABX04304">
        <property type="protein sequence ID" value="ABX04304"/>
        <property type="gene ID" value="Haur_1661"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1661"/>
    <dbReference type="eggNOG" id="COG2962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054508_1_0_0"/>
    <dbReference type="OMA" id="HRMVWSL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1685-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="32571" checksum="AB139B0FC8851088" modified="2008-01-15" version="1">MKRGILYAAGAYACWGFFPLYWKLLNGIPALEILAHRMAWSLVFVGLLVVLRGQMGQFLQVLRNRRTVLIYATSAFLLGINWYVYIWAVNANHVVESSLGYFINPLVNVALGMLFLGERVRRWQAMAIGLATIGVVYLTVALGVLPWIALALAFTFGFYGLIRKTAALDSLQGLALETVVFFGPAAGYLLWLETQGKAAFGHQSWTVSLILAGAGIVTAIPLLMFAAGARQIPMTTLGLLQYINPTMQFSLGVLLYHEPISGTKLIGFAIIWIALALYSFESYLNRGQIAKPAAQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S3</accession>
    <name>A9B5S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1663"/>
    <dbReference type="EnsemblBacteria" id="ABX04306">
        <property type="protein sequence ID" value="ABX04306"/>
        <property type="gene ID" value="Haur_1663"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1663"/>
    <dbReference type="eggNOG" id="ENOG5032VBA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1233653_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1687-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025699">
        <property type="entry name" value="ABC2_memb-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13346">
        <property type="entry name" value="ABC2_membrane_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24425" checksum="B3B8ABCCAB45C780" modified="2008-01-15" version="1">MNSMINHLVRKDWQINRTMMSIYLGAMLVALAMLLADDNSFVFGIGVILILTVLMILGIHLTTSNVISEHTQKTLAFIMSLPVSGRQYALAKILANLSMFLLPWLLALVGSWLIILSRDSLPNGLAAITTLALIEILLSYCLIMMMGLVTGSQHGAIGAMALANLGFQGFLWGILQIPAIAQHRDSNSLAWNSTELSILAIQLVIIVGLLGITLVVQQRKTNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S6</accession>
    <name>A9B5S6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1666"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04309">
        <property type="protein sequence ID" value="ABX04309"/>
        <property type="gene ID" value="Haur_1666"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1666"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_662129_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1690-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735301" evidence="2">
        <location>
            <begin position="32"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="30"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="455" mass="49835" checksum="07AF9B15EA3DABA9" modified="2008-01-15" version="1">MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNTGTSPINNWTLTWSFNNQAISQLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWTGSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTATAIPTATRTPAPSATTVVPTATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGWDQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNVNIKVVGWAVRDRSTLQWSDNSVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHHYDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIFLHEVGHTFGLDDFYDWTPTGINSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U3</accession>
    <name>A9B5U3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PG_binding_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3098"/>
    <dbReference type="EnsemblBacteria" id="ABX05736">
        <property type="protein sequence ID" value="ABX05736"/>
        <property type="gene ID" value="Haur_3098"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3098"/>
    <dbReference type="eggNOG" id="COG3342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068244_0_1_0"/>
    <dbReference type="OMA" id="CHPWAGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3130-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010430">
        <property type="entry name" value="DUF1028"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014927">
        <property type="entry name" value="PG-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06267">
        <property type="entry name" value="DUF1028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08823">
        <property type="entry name" value="PG_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_2" evidence="1">
        <location>
            <begin position="207"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="30270" checksum="F5BCB9343E3EC249" modified="2008-01-15" version="1">MTFSIIGYDPTTGDLGVAVASKFLAVGSVVSWAQAGAGAIATQSYANISFGPDGLALLAQGTSAQATLDQLLAADEGREQRQVGVVDAQGNAATWTGNACHSWAGGRTGAGYAAQGNILTGADVVEAMATTFEQTQGELAERLLAALLAGDLAGGDQRGRQSAALYVARKGGAYGGVLDRYIDLRVDDHHNPVPELQRLLQLHRFYLTPPKPEDLLPIDQAIALEIQTMLQQVGYYQGELSGVYDAATHSALQAYGGVENLEERLVSETHIDQQVLNYLRQHFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B600</accession>
    <name>A9B600_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3156"/>
    <dbReference type="EnsemblBacteria" id="ABX05793">
        <property type="protein sequence ID" value="ABX05793"/>
        <property type="gene ID" value="Haur_3156"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3156"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_4_0"/>
    <dbReference type="OMA" id="GYNGWHD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3188-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="46709" checksum="5A26F7D7B5D47987" modified="2008-01-15" version="1">MSAAQLPKVSGEALNLTKSMELLVQAEAIVPGTTQSLMKRPEQFAYGSFPVFIDHGDGALVTDVDGNQYIDFICGLGATTLGHNHLAVVEAIRNNLDKGLIHSLPTEVELRATQALIDIIPNAEMARFFKTGADATSAAVRLARHLTKRERIITVGYNGWHDHFMYYTPGVPAVLSQYTEQVSLMAPHEKPNLIAAINNHGDQLAAVLLSMPYKHCLDAEYLNEVKAACHAVGALFVLDEVVTGFRLALGGAQEFYGVDADFVCLSKGIAAGMPLSAITGPKKHLERLSDLQVSTTFGGEMLSLEVCYEVINIYRNTNYFEHVAKLGQRLREGVNAKAEALGVALRVCGYDAIPFFSFAPDMPTHARLMEALLGTLAKRGVILRRDVNFLTSAHTVEQIDFTIEAVAQGLQELLDRGIIESTNGKEQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B7</accession>
    <name>A9B6B7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3692"/>
    <dbReference type="EnsemblBacteria" id="ABX06328">
        <property type="protein sequence ID" value="ABX06328"/>
        <property type="gene ID" value="Haur_3692"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3692"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_5_3_0"/>
    <dbReference type="OMA" id="EFWILLK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3734-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="461" mass="49129" checksum="1BB7DFE377DD0370" modified="2008-01-15" version="1">MAIPLGAAQGRSSQRSAVLKLGLPAVGEQLLSLMVGLVDTYVVGHLSLAVATANGYDRQIALAATGISSQVTWTLITFFMAVALGSTVVIARFVGAGEREQANQTLRQALLIGLAMGLLSLFLAYSFAPQLMDLLGANEQVRQYGAGYLRISALSMPLMAMLYVGNAALRGSGDTRTPLKVMLVVNGINAGLSLLLVNGYFGFPAMGINGAAFAAMSGQGIGGLMVLATLIRGRSGLKLDQIPRPDGNLIWRILRQGLPYGAEQFIFQAALLIFIHLINDIGTAAYAAHNTIITIESISFLPGMGLAVAATTLVGQHMGANQPQQASESGFEAFRLGALFMGAIGLLFVVAPEVFLRFFVADEEVVQLAALPLRMVGFAQPALAANFIFSGSLRGGGEPKWPLISKMLSVWCVRLPLAWLLVKHFDLGLNGIWLAMCTDFAVQGSLAWWRFRQGKWQSAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C8</accession>
    <name>A9B6C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0179"/>
    <dbReference type="EnsemblBacteria" id="ABX02831">
        <property type="protein sequence ID" value="ABX02831"/>
        <property type="gene ID" value="Haur_0179"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0179"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056466_3_2_0"/>
    <dbReference type="OMA" id="MIFRAKA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-182-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="24728" checksum="1143DDDF02226239" modified="2008-01-15" version="1">MSLLSRVRDLVSANLNAMLDKAEDPEKMVNEYMRQLQEQLYEAKTAVASAMADETKLHNKMVTFQTEADQWQSKAEAAVRASDDELAKAALGRKANAQKMADTYRQQYEQQDEQVEQLQKALVSLESRLSEAKAKKELIIAKKNRAETQEAIQRTVQGLGNLNAMDKLSQMEERVDDRLAQADAMSKLEGSSLETRFADLERDTAVEDELAALKAKMGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D3</accession>
    <name>A9B6D3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="9" type="ordered locus">Haur_0184</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0184"/>
    <dbReference type="MEROPS" id="S16.A04"/>
    <dbReference type="EnsemblBacteria" id="ABX02836">
        <property type="protein sequence ID" value="ABX02836"/>
        <property type="gene ID" value="Haur_0184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0184"/>
    <dbReference type="eggNOG" id="COG1066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018264_0_1_0"/>
    <dbReference type="OMA" id="FELMRLA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
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        <property type="term" value="P:methylation"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="RecA_ATP-bd"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
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        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
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    <feature type="binding site" evidence="5">
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        <ligand>
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        <source>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="ABX02836.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="476" mass="51050" checksum="BE516D8A8F672687" modified="2008-01-15" version="1">MAKQRTIFVCQQCDAQFPRWMGRCTECGSWDSLVEQVIAKSAGTTGGSTRSPIGVSEPLRLPDIQLGDVQRLPVRGSEFARVLGGGIVPGSLVLIGGDPGIGKSTLLLEQSAALAETAGDVLYISAEESQQQIKLRATRLGLSAQRLYILAETSLDTAIATIERMKPVLVIVDSIQTVYSESVTSAAGSVSQVREGALRLQRVAKQHNISIMLVGHVTKEGAIAGPRVLEHIVDVVLYLEGERFHQYRLLRSVKNRFGSTNEVGVFEMNQGGMVEVTNPSQIFLAERSTNSPGSAVAVMLEGTRPLLLEVQALTSHTANAQPRRTANGFDQNRLAMIIAVLSKRVGVPLFNQDIYVNVVGGLKVTEPAIDLAVATAITSSFRNQRVEPNTVLIGEIGLSGELRSVSQLDRRLNEAAKLGFHNAIVPQIDALPQIDAFQVTGIRSLIEAVRAALIGAPRPSPGEPPTAKATTDTNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F1</accession>
    <name>A9B6F1_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Haur_0202</name>
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        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02854.1"/>
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    </dbReference>
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        <property type="gene ID" value="Haur_0202"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-205-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="108" mass="12657" checksum="25E0AC498EBF57EA" modified="2008-01-15" version="1">MHARDFVQPGEQLLVLFTRGHLLTFNNDGTGTSGNWDMAGNRKIDRVLIYYRDDSSNINKLYLATYKDVEKVEDGRYCVYFEHCQYVGKTEQNWVEFTGAQQAVRYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G7</accession>
    <name>A9B6G7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0218</name>
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    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0218"/>
    <dbReference type="EnsemblBacteria" id="ABX02870">
        <property type="protein sequence ID" value="ABX02870"/>
        <property type="gene ID" value="Haur_0218"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0218"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_7_0"/>
    <dbReference type="OMA" id="VMVPQDG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="35"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="350"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="383"/>
            <end position="390"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="603" mass="67118" checksum="F666D1827BF70407" modified="2008-01-15" version="1">MFAGLDTENYDRQYGDRELMGRMLSYFRAHRRTAFWTIALICGLGLLNTIPPFLVAQAVQRIGEANPDWNFIWLLASGGVVFGVLQWAMGWLRQRMTAQIVADVISALRNDAFNAAISHDLSFFDELRSGRIISRITSDTQEFAQVSRLIIEIVSQVLTVIALLVYLLSVSVPLSLGIIGFTPIVIGLALGFRRLARFVTRKGFQVLGEVNSSIQEAVTGISIAKNFRQEARIYGEFSEINQQSYGVNLRRGFVLSNVFPTLNIVSGFGTAALIYWGGLSVIDLTISLAAWYVFVRSVDLFWFPLLNISAFWSQFQAGLAAAERIFALIDAEHSVKQHDQQTTKRLRGEIVFDHVEFRYGRKEPVLNDFSLNIAPGESIALVGHTGAGKSSIAKLITRFYEFQSGKITVDSHDIRSLDLRSYRQQLGIVTQTPFLFDGTVADNIRYAAPQLSDAELEAVANQIGGGEWLETLPQGLQSQVGERGNKLSLGQRQLVALTRVLAAQPAIFILDEATASIDPFTETQIQQAMDLILSRSTAILIAHRLSTVRSADRIIVLNQGQIIEEGNHDQLMQQGGHYADLYDTYFRHQSLSYIESRGAVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J2</accession>
    <name>A9B6J2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DOD-type homing endonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0243"/>
    <dbReference type="EnsemblBacteria" id="ABX02895">
        <property type="protein sequence ID" value="ABX02895"/>
        <property type="gene ID" value="Haur_0243"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0243"/>
    <dbReference type="eggNOG" id="COG1372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150943_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-246-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="1">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="26123" checksum="E78AD6AF59D6AA2D" modified="2008-01-15" version="1">MARPAASNPFFRTWSPTMAYVLGYWWADGYMRIHSNTGGHFVQIASIDIEHLQAIADAMGATTALRQVRKESTCHEMVICNQGLYHDLLNLGGIPNKSHVIGFPNVPTEYLVDFIRGFIDGDGTLVWNGDRPVIQIYSGSQQLLLETGRCIELMTGIPAPNISHNRNNYYIKWSTIRAKCLAIWLYHNNSLMLARKAAIAQQFEQWQPKKSPERGTITEKMRLHFANYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P6</accession>
    <name>A9B6P6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ordered locus">Haur_1712</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1712"/>
    <dbReference type="EnsemblBacteria" id="ABX04355">
        <property type="protein sequence ID" value="ABX04355"/>
        <property type="gene ID" value="Haur_1712"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1712"/>
    <dbReference type="eggNOG" id="COG0221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073198_1_2_0"/>
    <dbReference type="OMA" id="DEPTFPG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19938" checksum="6A977249CEC6A389" modified="2008-01-15" version="1">MNIWHDVPFGEDAPEVINVVIEIPRGSRNKYEIDKDTGLVKLDRVLSSAVYYPGDYGLIPQTYCEDGDPLDVILLLNFPTFPGCLVEARPIGVFGMIDGGENDDKILAVPANDPYFANIKDLADVPPHFIKEVTQFFASYKALENKTVQVGEWQGAEAAKQRVQDSIQLYNENFRKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z9</accession>
    <name>A9B6Z9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3230"/>
    <dbReference type="EnsemblBacteria" id="ABX05867">
        <property type="protein sequence ID" value="ABX05867"/>
        <property type="gene ID" value="Haur_3230"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3230"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435352_0_0_0"/>
    <dbReference type="OMA" id="MHHRVRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3265-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="108"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="287"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="636" mass="70788" checksum="C23E95BE35511A16" modified="2008-01-15" version="1">MIDTSAPSAAILAILQNDNAVAQAQELRAFGATWQSQNADPQMLTKLGIEAATQARLDPSAVVTDLLLGYAAAREEQRTRHWQNHLMRRVQQLDGLHRIISAANSTLDIDASLQTVVDTVSDVMRVDVCSIYLFDQHRRMLRLVATRGLNPKAIGTVEVEIGVGVTGWAGELGKPVAIFDVRNEPRYQLEPLLEEWHFRSLLAVPVILFASERHHIETLQGVITVQNRDPHEFSQEQTSYLEVVAGEIALSIANAQMYQQTDARLHQKIRELTTLQRVTAALASTLDVDTLLHLIVEQAVKIADVDRTDIFQVRPNNKVKMLASYGPGRTSGVEDMIVQVIREHRAIAVPNAYTDERWSGVQAIAYREGFHSLFALPMRTGNRIIGALCFYSYAPRHIEYEQVQLLTTFADEGAIAIENARLYEETQRNLTIKSTLLQEIHHRVRNNLQTISALLQMQARRLNTETEGRQALDDSVRRIHAIAAVHNLLSHDGEGQTTVQDIAKQIAENIQMSLPSETPVEFLITGDSVSVNARAATVLAIVINELVHNALDHGLSAEGGIIGIDGWMENEEQACVQVRDDGPIRPEPVKRRVSTGLGLGIIETLVNTDLGGKFEFKRETEWTRALITFAPDELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B773</accession>
    <name>A9B773_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3720"/>
    <dbReference type="EnsemblBacteria" id="ABX06356">
        <property type="protein sequence ID" value="ABX06356"/>
        <property type="gene ID" value="Haur_3720"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3720"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025263_0_0_0"/>
    <dbReference type="OMA" id="YGREECE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3762-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="636" mass="71353" checksum="5BC910AD5B6F5D37" modified="2008-01-15" version="1">MSAPASRAKTTATPRRDDDHELRNYRLEERIGQEELTTIYRARHLTLDRPVEVHVLRRSDWVSVSRFGQAARLAARLKHPTIVPVIDAGHDDRFGYYLVTPPLGGRLLQEVLEDGALSIGDAVRIFSDIAKALDTIHAEKIVHRDIQPGTIVVTEAIHDQAVTRHGFLTNFSLAWSSDGPDLSQLEEADYLTAYAPPEQDFKQNATEPSLDIYALGAVLYHMLTGEVPPAPGQTPKSLGDFNVALAPADRVLRRLLSPQASVRYSSANQAAAALRQALREALPAETSTTLAPIAASSVESEWLENPVETVLVGILDGDFVQRGREWGRQLHEPTNLRSVLNRWSGQNMLRRRDLGNALVPERVVSYNFYTYELRAYYETRTTPEPREKPYQGSRISTSQNPPGVWQVILPDPQPFDEIRPTEMIIPNSERVEMCIYCGGKGDLHCTKCHGRGLLETKRVQTNPDGTKERRTVTLDCPECEGEGQADCGRCQGSGQVLTEDVFYWSRWGKLWENTDDEAGLPLADIREKSQQVYTAQIDVRDTKWHAIAPLHELLQAAENVDADQQTRLLHAELTIHGTPVTEVDYTERNQAHTLYMIGFEPTIIRGNFTLFDRERIVLYSVIGVLVLIAVIGFLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7A7</accession>
    <name>A9B7A7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3754"/>
    <dbReference type="EnsemblBacteria" id="ABX06390">
        <property type="protein sequence ID" value="ABX06390"/>
        <property type="gene ID" value="Haur_3754"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3754"/>
    <dbReference type="eggNOG" id="COG0350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_2_0"/>
    <dbReference type="OMA" id="SACAMNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3796-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="84"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19179" checksum="7C7F33C126DFFE84" modified="2008-01-15" version="1">MQQLTIEQIATPIGAVVIISSPQGVVYLDFGDNQARCQRLLSQRYGQFALIPASQNLWADAVASYFAGDLRALDVITVDLAGSEFQCKVWLALREIGVGQTMSYGELAAKVGTPSAARAVGMTNGQNPISLVLPCHRVIGANKSLTGYAGGLERKRWLLRHEGAQFKDTPAQASFELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J9</accession>
    <name>A9B7J9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0320"/>
    <dbReference type="EnsemblBacteria" id="ABX02972">
        <property type="protein sequence ID" value="ABX02972"/>
        <property type="gene ID" value="Haur_0320"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0320"/>
    <dbReference type="HOGENOM" id="CLU_1945810_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-323-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="14238" checksum="6FE078D1B3CEFC18" modified="2008-01-15" version="1">MYNSSTISRRIALAFVTFGLIFVSFVYTALTSSQTPQFGTPAAANTAWQWGDIEGITVTQQLQTAPLNTAWQWGDIEGITVTQQLQTAPLNTAWQWGDIEGITMTHQLQTAPLNTAWQWGNIESSKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R9</accession>
    <name>A9B7R9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase</fullName>
            <ecNumber evidence="3">3.3.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + isochorismate = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11112"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58764"/>
            <dbReference type="EC" id="3.3.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
        <text evidence="4">Binds 1 phosphopantetheine covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1804"/>
    <dbReference type="EnsemblBacteria" id="ABX04447">
        <property type="protein sequence ID" value="ABX04447"/>
        <property type="gene ID" value="Haur_1804"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1804"/>
    <dbReference type="eggNOG" id="COG1535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_2_0_0"/>
    <dbReference type="OMA" id="RDIKPFF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1832-MON"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016291">
        <property type="entry name" value="Isochorismatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001111">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01398">
        <property type="entry name" value="ISCHRISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="203"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4 5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001111-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="31441" checksum="15E7B0B3F4DEBD74" modified="2008-01-15" version="1">MALPSIAAYAIPTELPTNRANWAAEPQRVALLIHDLQNYFIDAFPAGEEPISSVLRSIASLRDHAHALGIPVFYSAQPGDQAPEDRGLLSTFWGKGLSTGTPPEIVAPLAPQAGDQVITKWRYSAFQRTPLRELLREAGRDQLIVCGVYAHLGCLLTACDAFMQDIQPFFVADAVADFTLDEHRMALQYAAGRCAVVTTTEQLVRELGYNQLRSELHDLLDDVESIGADDNLLDWGLDSVRLMTLAERWRAAGCEVGFAELAETPTLAEWWQRRFAAPLLEQAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S8</accession>
    <name>A9B7S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FOG: Ankyrin repeat-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1813"/>
    <dbReference type="EnsemblBacteria" id="ABX04456">
        <property type="protein sequence ID" value="ABX04456"/>
        <property type="gene ID" value="Haur_1813"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1813"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_346402_0_0_0"/>
    <dbReference type="OMA" id="REIQFLY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1841-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="624"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="657"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="815" mass="89364" checksum="5B4D74D93FC5A51D" modified="2008-01-15" version="1">MNLNSLKKLLKHQAYHQILEHLQTGPTWKQKSLDHALYQLASQPAETLIATLLSAGANPNQSLQDNRYISLHRAAIYNRYAIAELLLSHGANCHAQSAKQQTPLHLACLNGHFELAQLLWHNGADLHAQADSNFTPWLYAASSGNLQLLRWLLDQAVDIDQTTANGISALTLAAWNGHQAAVEWLLANDAAIEGPPTRTRTPLHAALSKGHMAIANLLLDHGAAANAITSEGNSCVCLAAWHNATDLVDRLLQLGSPINCAMAKPHATALHAAAQLNNPAMAQQLLANGAKINALNPQGLMPFHTAISTICATKSADLALIEVFLRMGADPNQPSYAIKQLGKETQVREHWRPLGYVLAQKRRDLAECLLAYGAELNLPSYGKWAMEQTPLEVVASAEVIDQEAGELFSWLLSLKPQIPPKLLPSMLITQKFGFAQQLIAAGADLHAPDVLGAAITAKNEHYVHDFLARGVNVDSPYRNYTTVLQLALSSYPQFALRLIEAGADLTHLVDENPSLNYPMLIRQQRSNRPAISNLMLLDLIAEAMLAQLEPANPAYQALLDQEFAERVCTANETTWQIWLARGANIHALNHAGLLGFSQLCVHGDLAGAQTLYANGANINQTDHFGRTALHWAVERQQLASIQQLLAWAADMHSATPYGYTALHYAALANRLDLVELLLQAKADPTVQLTTGRLQGWTALHCAYAVDNQSLIKLLHPLTPTITPPEPGSQHIQGTYDVTMAHNGWHKPRPISQQTQRCPACAEHMLYNTAHSFDGSGQLADRIEIYRCGNCQAVFWENSMATWRSRLQPWSSFVPD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B891</accession>
    <name>PDXS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="1">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="1">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pdxS</name>
        <name type="ordered locus">Haur_3808</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B891"/>
    <dbReference type="SMR" id="A9B891"/>
    <dbReference type="STRING" id="316274.Haur_3808"/>
    <dbReference type="EnsemblBacteria" id="ABX06444">
        <property type="protein sequence ID" value="ABX06444"/>
        <property type="gene ID" value="Haur_3808"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3808"/>
    <dbReference type="eggNOG" id="COG0214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055352_1_0_0"/>
    <dbReference type="OMA" id="RYANRGW"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0704">Schiff base</keyword>
    <feature type="chain" id="PRO_1000188230" description="Pyridoxal 5'-phosphate synthase subunit PdxS">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <sequence length="293" mass="31448" checksum="ED189C5706D631AA" modified="2008-01-15" version="1">METSTFTTKVGLAQMLKGGVIMDVVTPDQAKIAEEAGAVAVMALERVPADIRKDGGVARMSDPEMIQGIIEAVTIPVMAKSRIGHFVEAQILEAIGVDYIDESEVLTPADEEHHTNKHNFKVPFVCGARNLGEALRRITEGAAMIRTKGEAGTGNVVEAVRHARTMFAEIRRLQTLDPDELFVAAKNLQAPYELVKQIAELGRLPVVNFAAGGIATPADAALMMQLGVDGVFVGSGIFKSGNPAKRAKAIVEATTHFRDAKLLAEISRNLGEAMVGINIDTIPENELLAKRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A8</accession>
    <name>A9B8A8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3825</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06461">
        <property type="protein sequence ID" value="ABX06461"/>
        <property type="gene ID" value="Haur_3825"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3825"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_307923_0_0_0"/>
    <dbReference type="OMA" id="VPDRSWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3867-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="572"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="756"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="782"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="816"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="471"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="959" mass="108212" checksum="87FF99A4C83C35B1" modified="2008-01-15" version="1">MLWYNGTLLSMKRFEAGLVQDWWQRRAAWSLRQWIITIASVLLMALCLLTALYQLPTHVRIASDGLGDQPFLVSSEALGQAATDLGTVFPDELDATGGRFRWTRGSTQIQIPALGAHSSYRLELDVVGWPDDVLRSDVRQPFVHVLVNQQLIAVFEASSQRTIYQLNTPALNQSNLELELRLSHDPQQLAPLDNTATFTGTTLYPNDRRPHGLRLYGLSATTNTVGFNLPAWSLIWRVAVALGLILLAGWLYPRERLPLFLLGLLLVVFWLTLGYLARHWLLPSFELVLLGLGFVVVWNWQRQIIDTWLHFRQRLLQGQNLDYGLAVAALIGLLAISWPSLSQAANEWLPKAKKLDPGAIIVVSLAVASLFIAGFYWGDLNRLLDRLNRRLRTRQGLGWALLGLVVGVWLVYSWGVIRQINYLGNADYSDNGVVARNLVAGRGWVVDYVTQFFKLYPDGSVTRVQETWPMLQPVWIAPFFALFGPEPWAAKIPNLIFFSLLSIVVYRIARQLWDQRVGLIAVLLVLINRHMFRLMIYSTSDLAFVLFYTAAIWLLWRSLVTHSKERLLGSGLIIGLMCWQKTSAVIVAIGMGLWLIWRLWQVEDRWKAYRTAALWWVLPAVLVFSPYIARNLHEFGKPAFSTESYDAWIIGYTNFDSIYNIYTNEQGLPGSNGLPEPSWILRWGYQKTFDKIGNQFEATRNYLLPASPALGMFSGRGNLMGNNDQGVNGQPYVWLMLGAWLSLIGLIAARRQQASLIALVGASFTPYIIFLALYWHADEERYFVPLVPFLALLAAGALVAIHDAIARCWNQRGRPLALLVAAQLLVLALTPGWVEAANKSATVAGSEYAEWQPDLQAFEWLRQNTPPEAVVMTRVPWQLNFHAERAAVMNPNVADLAVIKQVADYYKASFILVNAVQNNKDQAQIGLGRLLKGEELPGFVLRASFAGPKNRTVYIYEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8C5</accession>
    <name>A9B8C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3842"/>
    <dbReference type="EnsemblBacteria" id="ABX06478">
        <property type="protein sequence ID" value="ABX06478"/>
        <property type="gene ID" value="Haur_3842"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3842"/>
    <dbReference type="eggNOG" id="COG0762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136788_1_1_0"/>
    <dbReference type="OMA" id="YFFEIVN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3885-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9572" checksum="A563DC377110E8B8" modified="2008-01-15" version="1">MGNFISQFFLLLIPILEIAIFVRIIMSWFDPTGQSRFALILREITDPILLPIRRVIPSIGMFDLSPLIALLILQVLQTVFQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D3</accession>
    <name>A9B8D3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3850"/>
    <dbReference type="EnsemblBacteria" id="ABX06486">
        <property type="protein sequence ID" value="ABX06486"/>
        <property type="gene ID" value="Haur_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3850"/>
    <dbReference type="HOGENOM" id="CLU_1935154_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3893-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14370" checksum="DC9162F0C9F6CCF6" modified="2008-01-15" version="1">MAGFSDLLMISGILVFFLLSSLSLGYSIGQLASPYATIKLLPIVIAASLGLASLAGCYWCFSSFSRFDLIDRCRPDGTGFCASNGQAIDQFEQALLQEQRWQFGLWIIIPLIVLLGLTWLFKRRTPRLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I9</accession>
    <name>A9B8I9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07653">
        <property type="protein sequence ID" value="ABX07653"/>
        <property type="gene ID" value="Haur_5023"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5023"/>
    <dbReference type="HOGENOM" id="CLU_952402_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5086-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="32965" checksum="47F467A24108B857" modified="2008-01-15" version="1">MQEIEIDFTDVTTIPPDPTGKPRHAVEAFAWIDAGTAIPFAVVVDGNFHMASVIRTTAQILQTHGVPPLIRMDRNPRFVGSTAKADFPSPFMRLLLNLGIQIDLCPPQRPDKKGVVERFHKTYQEECIVKHWPTTEAEAQAHLDTYCTWYTTERPHQGRGCANRPPAAAYPDRPVLPAVPAMVDADGWLRARDGWTVVRQVNRHGAITIDTQHYHIGTRSAGQEVAVTLEATTAELVVRSGETVIKRLRIKGLLGGMMSFEQLVNQLCEQCRQERVRLRNRQPARPRKRWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8U4</accession>
    <name>A9B8U4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_5130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07758">
        <property type="protein sequence ID" value="ABX07758"/>
        <property type="gene ID" value="Haur_5130"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5130"/>
    <dbReference type="HOGENOM" id="CLU_036805_8_0_0"/>
    <dbReference type="OMA" id="QEAWIAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5192-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="353" mass="39926" checksum="EAE7B1627FB93A1A" modified="2008-01-15" version="1">MTPIKKHTHSPVIGQAEAQATFQQLVQHQIRQAIRATFIDILEEEVAAFIGAQPYERTDERRDHRAGHRSRTLGTTAGVIDDLPVPRTRGGFRTQLFDRYQRRMHDVDTLMQDMFVGGVSQTAVGTVVEHLTGNAPSPSTVSRVFHTLDDEFQAWQARPLPPRSCYAFADGTYFSVIYNGQGQKMPILALIGITPDGQREVIAFTTGERENQGAWESLLADIKDRGVETVDLWITDGHQAMLNAIAAKFPASQRQRCVVHKMSNIESHVPEKYRDALHAELRAIFYQPDRAQADQAAAAFMAKYERQYPERTFEEVKKRSKKIATAFRNEGSCLLLFYAVVRTLQLRKIRMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B909</accession>
    <name>A9B909_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07823">
        <property type="protein sequence ID" value="ABX07823"/>
        <property type="gene ID" value="Haur_5196"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5196"/>
    <dbReference type="HOGENOM" id="CLU_061564_0_0_0"/>
    <dbReference type="OMA" id="ITHASLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5258-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="247"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="39456" checksum="04D8182496A3E27A" modified="2008-01-15" version="1">MKQLFAWLSFIDHPVDDVRRRGQVVIGILCSLLVIAVMGLFSLLGDPVQHGAAGSIVFSIGLFLSLIFIVRRGYVALGGWLVVLATTLSVVLPQVIAGFSNQSLAYALIPALIAGVVFRPWQILLVAIGLTMVILGMVWMLPPDPQVMPTQRSIITHASLMTFVSAIIGFVASDVNHRAFKTIRDGQHHIAQQHHDLMVINRHLAQQADEQTAAVATTVQHLQERTSVQERLLATVTLQRETIRAMSIPVLPVAPQVVVIPLIGVLDSARLVLLRDGALAAIQRYTANHLILDMTGVEIVDSQVASGMMQVIQAAHLLGTHMLLVGVRPEVAQTMVALGLDLGSIDTAATVYEGVHRIQHTGSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B925</accession>
    <name>A9B925_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07839">
        <property type="protein sequence ID" value="ABX07839"/>
        <property type="gene ID" value="Haur_5212"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5212"/>
    <dbReference type="HOGENOM" id="CLU_1048762_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5274-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="276" mass="30590" checksum="9C3924A542E0ED4A" modified="2008-01-15" version="1">MRFYDRLRWKLGLPSVPIIDASSIADAIDALPTAVPRYPSASYGVVAPPFDAFFVEATARDESDTLLGQRGVLVRATTDTIHPVTPERTRWTLTLEAFMYVKGQGMYGYQQLAVVFLDRQGKIINDMLKGVPLLPNPTRYERIGQTPTPGATLHCVYALKAINAMHQSCPAEHLTPTDEERQHYQRKAGASAEPSDYYLLKVRPTAKGGFEAIGHGLAAEPRRAHGVRGHFKYYDPERPLFGRAGQHGMLWIPAHERGDAERGTIEKGYQVESGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9B5</accession>
    <name>A9B9B5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5302"/>
    <dbReference type="EnsemblBacteria" id="ABX07929">
        <property type="protein sequence ID" value="ABX07929"/>
        <property type="gene ID" value="Haur_5302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5302"/>
    <dbReference type="HOGENOM" id="CLU_1765534_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5364-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="19633" checksum="0E9202FA6086D31E" modified="2008-01-15" version="1">MRFQCLVERPVMSFYKQLFLMLPPHDARGMADGLAGLGYRPDPWAKTSSLHMIQSFGDDSIVEIYCSEEAFIWNADFPDVWHQITVQVGTDQWVEYGLYFTYHPEAEAAVLRLVAWMHTYDLSLTVVTPFHHVFGPADLPLTDRAMLYWGDDPWDDDDYHRLLGDNRTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU95</accession>
    <name>A9AU95_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0363"/>
    <dbReference type="EnsemblBacteria" id="ABX03014">
        <property type="protein sequence ID" value="ABX03014"/>
        <property type="gene ID" value="Haur_0363"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0363"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_0_1_0"/>
    <dbReference type="OMA" id="MALGFCA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-366-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="29936" checksum="B1E9B3F13F5B85BD" modified="2008-01-15" version="1">MAIIVTDSTADIPAGLAAENDIHVIPLTVNFDAESFADGVEITHDQFYARLVESNNLPTTSQPSVGAFEQLYRAIGNDEPIISIHIAGKLSGTIRSAQQAAELLPDFDIRVIDVQSTTMSQGWAALLAARAAKEGKSADEIVALVHSIVERTRLLAALDTLRYLEKGGRIGKTRALLGTLLNVKPIIDVRDGEVKPFEQVRSKKKAVARLIEEARSMAPFEELAVLYSRNEAEAREFAQSLNEIFPADRIVLAEIGAVVGTHIGPGALGFTGVRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC3</accession>
    <name>A9AUC3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0391"/>
    <dbReference type="EnsemblBacteria" id="ABX03042">
        <property type="protein sequence ID" value="ABX03042"/>
        <property type="gene ID" value="Haur_0391"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0391"/>
    <dbReference type="eggNOG" id="COG1937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130332_2_3_0"/>
    <dbReference type="OMA" id="YCIDVAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-394-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="10833" checksum="951DC705560A6EBF" modified="2008-01-15" version="1">MIDEQTEALVRRLKSIEGHVRGVQRMLEEDAYCIDVLRQTLAIRRALEKVDALVLERHLSTCVTNAIRSPNEGEREQAITEILEIFAATRSVSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE5</accession>
    <name>A9AUE5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FeS assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0413"/>
    <dbReference type="EnsemblBacteria" id="ABX03064">
        <property type="protein sequence ID" value="ABX03064"/>
        <property type="gene ID" value="Haur_0413"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0413"/>
    <dbReference type="eggNOG" id="COG0396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_0"/>
    <dbReference type="OMA" id="MAMLEPK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-416-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="29116" checksum="4F7D6A90AFF9F2D6" modified="2008-01-15" version="1">MSANNLVIRNLHVAVDGKEILKGINLTIEEGKIHAIMGPNGSGKSTLAYTLAGHPRYEVTEGEVWYKGQDVLDLEPNDRSKLGLFLAFQYPVAVAGVTVANFLRAALNAHRAQEGVDPKSTAIPMAEYRKVIKARMDMLEMAPDFARRYLNEGFSGGEKKRLEILQMAMLQPAMAIMDETDSGLDIDALKIVAEGVNKVKAEKPELGVLVITHYQRLLNYIKPDYVHVLMNGQIVREGGPDMALELEEKGYDFIREEVFGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL4</accession>
    <name>A9AUL4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1898</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1898"/>
    <dbReference type="EnsemblBacteria" id="ABX04541">
        <property type="protein sequence ID" value="ABX04541"/>
        <property type="gene ID" value="Haur_1898"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1898"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_0"/>
    <dbReference type="OMA" id="QIFKHHC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1927-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="111"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="36198" checksum="C7BAF45041E4B9B9" modified="2008-01-15" version="1">MRVNFIFFLIKRLAMMAVSLVVIIAISYTLLAKAPGNFMDVQRAVAAMTTLANSNSETFKIQKALFDERYGLDKPLYMQIWTYTKNAVTFDFGPSFQSPSILIQDMVRERLPRTLLIVFLGIGLALIVGIPLGVIAGFRRNTWIDYIVTGFSMIGQVVPVYVLAIVLILIFAGQVWNVLPNGGWATPVPTFKQLILPVLTLALGPIAGIARFTRNQVAETMSQEFIRTARSKGISERLVIMRHALRNSLIPVVTTTAPQIAYALVGSVWIENIFRIPGIGQLFATALGARDYPLVITSTVILALGVMLANLLADILYSILDPRIKLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ0</accession>
    <name>A9AUQ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0848</name>
        <name evidence="3" type="ordered locus">Haur_1209</name>
        <name evidence="4" type="ordered locus">Haur_1934</name>
        <name evidence="5" type="ordered locus">Haur_2461</name>
        <name evidence="6" type="ordered locus">Haur_2872</name>
        <name evidence="7" type="ordered locus">Haur_2890</name>
        <name evidence="8" type="ordered locus">Haur_3071</name>
        <name evidence="9" type="ordered locus">Haur_3220</name>
        <name evidence="10" type="ordered locus">Haur_3427</name>
        <name evidence="11" type="ordered locus">Haur_3532</name>
        <name evidence="12" type="ordered locus">Haur_3610</name>
        <name evidence="13" type="ordered locus">Haur_3831</name>
        <name evidence="14" type="ordered locus">Haur_4720</name>
    </gene>
    <organism evidence="4 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0848"/>
    <dbReference type="EnsemblBacteria" id="ABX03496">
        <property type="protein sequence ID" value="ABX03496"/>
        <property type="gene ID" value="Haur_0848"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03857">
        <property type="protein sequence ID" value="ABX03857"/>
        <property type="gene ID" value="Haur_1209"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04577">
        <property type="protein sequence ID" value="ABX04577"/>
        <property type="gene ID" value="Haur_1934"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05099">
        <property type="protein sequence ID" value="ABX05099"/>
        <property type="gene ID" value="Haur_2461"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05510">
        <property type="protein sequence ID" value="ABX05510"/>
        <property type="gene ID" value="Haur_2872"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05528">
        <property type="protein sequence ID" value="ABX05528"/>
        <property type="gene ID" value="Haur_2890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05709">
        <property type="protein sequence ID" value="ABX05709"/>
        <property type="gene ID" value="Haur_3071"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05857">
        <property type="protein sequence ID" value="ABX05857"/>
        <property type="gene ID" value="Haur_3220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06063">
        <property type="protein sequence ID" value="ABX06063"/>
        <property type="gene ID" value="Haur_3427"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06168">
        <property type="protein sequence ID" value="ABX06168"/>
        <property type="gene ID" value="Haur_3532"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06246">
        <property type="protein sequence ID" value="ABX06246"/>
        <property type="gene ID" value="Haur_3610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06467">
        <property type="protein sequence ID" value="ABX06467"/>
        <property type="gene ID" value="Haur_3831"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07351">
        <property type="protein sequence ID" value="ABX07351"/>
        <property type="gene ID" value="Haur_4720"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0848"/>
    <dbReference type="KEGG" id="hau:Haur_1209"/>
    <dbReference type="KEGG" id="hau:Haur_1934"/>
    <dbReference type="KEGG" id="hau:Haur_2461"/>
    <dbReference type="KEGG" id="hau:Haur_2872"/>
    <dbReference type="KEGG" id="hau:Haur_2890"/>
    <dbReference type="KEGG" id="hau:Haur_3071"/>
    <dbReference type="KEGG" id="hau:Haur_3220"/>
    <dbReference type="KEGG" id="hau:Haur_3427"/>
    <dbReference type="KEGG" id="hau:Haur_3532"/>
    <dbReference type="KEGG" id="hau:Haur_3610"/>
    <dbReference type="KEGG" id="hau:Haur_3831"/>
    <dbReference type="KEGG" id="hau:Haur_4720"/>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686571_0_0_0"/>
    <dbReference type="OMA" id="HWINTIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-862-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="146"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX06467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX07351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="46090" checksum="EA703158811E9E0A" modified="2008-01-15" version="1">MGSHNDLGLVYWVVTKPNPSQNRGRMPSIPALAHWINTILRTAVPTLSPWTARRLTDWLVSILLMPSITTRVVAWGCALGLSTAAHAASHERRLRRTYRDSQLSWSLHRAILATTLHIAPTESVTVIIDETTHTDRWTLLTAALWYHGRAIPLAWVLHPGYTRRATAFWTDVATLLERVQQVLPNAMSVVVVADRAFGCPAFTDQVAAYGWGWVVRVQGHTRIQLRGHTETMIRTLVTRGHRVVRRGHAFKKAGWRTVTVVAAWEATCHEPLLLVSNLEGIGAIRQAYGRRSAIEALFRDWKTAGWQWEASQSRSQTTQEALVLGMAIATVLVLLVGTAEAQAVLAERGDRPSPRRPWAARESLFRLGRYGVLRWLWTGTQPALGARLSLAGTALHERWATTVTRGGRLGTAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ1</accession>
    <name>A9AUQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S51 dipeptidase E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1935"/>
    <dbReference type="EnsemblBacteria" id="ABX04578">
        <property type="protein sequence ID" value="ABX04578"/>
        <property type="gene ID" value="Haur_1935"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1935"/>
    <dbReference type="eggNOG" id="COG3340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1244705_0_0_0"/>
    <dbReference type="OMA" id="DFSIFPH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1964-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="24129" checksum="81A2B004D6AD006E" modified="2008-01-15" version="1">MKYLLTSAGITNPSIHTALVKLLAKPIDQCNALCIPTASYANSNGSDSAWRFISGNEPRTPMCELGWKSLGVLELTALPSIDQSRWLPVVQQCDVLLVGGGDPLYLNYWMQQSGLAELLPSLSNLVYVGLSAGSMVLTPRIGEFFVGWQPPTGGDRTLGLVDFSIFPHLDHPELPYNTLARAETWAATIAEPAYAIDDQTAIKVVDGQVELISEGHWKQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV0</accession>
    <name>A9AUV0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3904"/>
    <dbReference type="EnsemblBacteria" id="ABX06538">
        <property type="protein sequence ID" value="ABX06538"/>
        <property type="gene ID" value="Haur_3904"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3904"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_0_0"/>
    <dbReference type="OMA" id="FYVMARF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3946-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="29"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="387" mass="42525" checksum="BDEE03611327FA43" modified="2008-01-15" version="1">MHPKSANRLAGFGTSIFSEISALAARYQAINLGQGFPDFAGPAFLKDAACSAINADLNQYAPSTGLPTLRAAIARTWERHSKASVDPDAEITVTSGATEAMFAIIMALINPGDEVLIFEPFYDSYPPNVLMAGGIPRYIRLHEPRWDVDFAQVRAAITPQTKAIILNTPHNPTGKVWSRAELSQLATIAIEHDLLVISDEVYDRLVFEDYQHCSIATLPGMWDRTITISSTGKTFSVTGWKIGYAIAPNSLTEAIRRVHQFVTFASATPLQAAAVVGLNAGEPYERQLLQFYNARREQLVKVLRDAGLYVLPPQGTYFVMADIRDLGWENDAEFCRYLISEIGVAAIPPSAFYHDGYQSGMVRFCFAKKPETIAAAAEKLKQLGSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV8</accession>
    <name>A9AUV8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3912"/>
    <dbReference type="EnsemblBacteria" id="ABX06546">
        <property type="protein sequence ID" value="ABX06546"/>
        <property type="gene ID" value="Haur_3912"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3912"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_723143_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3954-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="407" mass="43224" checksum="62C32DA00B96362C" modified="2008-01-15" version="1">MGNEIVQIDYQEANQLAQRFSKQQTHVQAILQSLRQTIQALENGGWMGDAATACFKEFHAEVVPAYTRLSNVLGEGQSTLQGIATLFRQAEEEAAALFRGEFAAAAGGESGIAQAVGGSGGNIQADNGGMYQTVQAFATNLSGSGGGQGQASELETLIRSLKDQCVDPNVILDAIAKATPAERQAILNDPQLMEYIRISEGTAADVLTAALLEGALFWPAGSGPANNGAIQSDVINPLTGEERTNDFALWMRGEAGPPDPLNGTMNCWEATMYAAYLSGEISESQLREIHQNAADAGADYYNVIEDAFGADNRSTWQSGDQPAAGSIVFFESDGSPLAHVAIATGRTTPDGKTEIMSLWVLPQDSNGNFVRSMQRTTIEDLQASMADAGIPLDQISTSPNPWDQPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUX4</accession>
    <name>A9AUX4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3928</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3928"/>
    <dbReference type="EnsemblBacteria" id="ABX06562">
        <property type="protein sequence ID" value="ABX06562"/>
        <property type="gene ID" value="Haur_3928"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3928"/>
    <dbReference type="eggNOG" id="COG1477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044403_5_0_0"/>
    <dbReference type="OMA" id="AFAKQCF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3970-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="33040" checksum="2A417A3E46F7FF75" modified="2008-01-15" version="1">MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVSETLWEVLGLALDAAAWSKGLVVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLAISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQAACLVDVGGDLATAGQRQDGLAWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLSATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV02</accession>
    <name>A9AV02_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3958"/>
    <dbReference type="EnsemblBacteria" id="ABX06590">
        <property type="protein sequence ID" value="ABX06590"/>
        <property type="gene ID" value="Haur_3958"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3958"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4000-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="531"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="707" mass="75933" checksum="B2FDB7DFB299B428" modified="2008-01-15" version="1">MSEAFIQTTSTKYPQKTAVIDGPRRITYEQLAASIGSFANELTAAGVTEGESIALVLPNCAEFVIGFYSTLHIGAVVLALNPLLKHNEINYYLADAQARVILTTKLYMGMCREIVAAAGRSIEIIALDGVLEGSRAAASERAAPAAADPHRPALFQYSSGSTGRPKKVMRTYGNLCAEGDNFTATVGMTHDDVILCLVPLFHAHGLGNCLLAATMVGATLVILEQPMDGNAVVDMPFIARCARVFELIEIERVSVLPGVPYVFSALSSAQVGFEPALGSLRLCFSAGNFLTRDVFDAFLDRFGIAIKQLYGCTEAGSVTINLEDDPSLAASVGLPIRNVELHICDEQKNRLAPDAIGEIAFKSPMLTSGYVGLEDINRDMFRDGFFFTGDLGRLDEAGRLTITGRKKIFIDVGGRKVDPLEIEDVLLTHPRVKEAVVVGIKAPYGGEFAKAVAVLDGECTQTELLQYCKDRLADFKVPRMIEFRNEIPKSPLGKILRKNLVDDSAVAEVEALGSTLSQHMRSTSSREQRLSLAKQCVRQQIARISGLDVAQIGLSNALSDFGLDSARAIELQMSLENLMGAGLSATMVWQYPDLDSLSGYLVDIVDAQTAGADPAAVPDRAAAPPAARPSAIQAIDDLSDDAIEALLRSQVDGILQPQNTTNAHTIPGLNEGDSAGIDRLAQLSDEDVTDLLLKEFARLSRTGQPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV05</accession>
    <name>A9AV05_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3961</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3961"/>
    <dbReference type="EnsemblBacteria" id="ABX06593">
        <property type="protein sequence ID" value="ABX06593"/>
        <property type="gene ID" value="Haur_3961"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3961"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_29_0_0"/>
    <dbReference type="OMA" id="VQVWPEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4003-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1472"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="3027"/>
            <end position="3103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3110"/>
            <end position="3130"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1507"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3130" mass="335858" checksum="4109B7C2CD2E1C9D" modified="2008-01-15" version="1">MSNPLEQLLKSLTPDKKALLAEYLRPKPEPVAVIGIGCRFPGGLVTPDAFWEFLKQGQDSIIEVPSDRWDIDAYYDPNPDAPGKMYTRWGSFLTDAPMFDASFFGLSPREALRMDPQHRLLLEVAWQALEDAGQQIDSLAGSQTGVFIGMINNDYPVRQLYADGAECFNDPYFSTGSSSSMAAGRLAYLLDLQGPTMTLDTACSSTLVATHLAVQSLQSKESNLALVGGSNVVILPDSFVSLCKMRMFSSDGRCKTFDAAADGFVIGEGCGFVVLKRLSDAIKDGDQVRAIIRGSAVNEDGRSSSITAPNGLAQQAVIRKALAVAGLKPQQISYVEAHGSGTSLGDPIEMESLRAVLGKGRSPDQPLYVGAVKTNIGHLAAGSGVAGLIKTVLSLQYKQIPPHLNFKTLNPGIPKGGAPFVVPTSLTPWTVADGPRLAGVSSFGWSGTNAHVILEEAPLAEPLSAARPTHVLLLSARTPTALEKATENLLGYLHRNPDCDLADVAHTLQRRRKHFAHRRAVICRDVAEAIAGLSGRHGRIHTGHVGQERPVAFVFAGVGDHYAGIAKGLYANEVVFRTAVDHALALLPPLDAAELRAALYPSNLPAAPAAGHGLLGRNGAAGGADGPLHQTALAQPAVFVVEYALTQLMMAWGVRPQALLGYSLGEYVAATISGVLSLEDALALVARRAQLIQSLPKGAMLAVAAGADAIQPYLGSEVCLAAVNSPSTCVLAGPHAEMNALAERLSQAEIACRPVETSHAFHSTMLAPAQEALTAFATTLTFNSPAIPYLSNVTGTWITVEQATDPAYWARHMVETVQFAPALGSLLADPAMMLVEIGPGQALGSFARQHPACDRQRFADIVATLPAKHEAQSELSAALSALGRLWVAGARVDWAAFAGAERRRSVALPPYPFERERFWIDLDSVPTTLAPARPARGKQANIADWFYRPVWEPHALALLAPTPTSGKHWLVFVDERGLGHELGARLEHAGDSVVRVQRGDGFARIDHQTFAVRPDTPEDYLRLLQSLASEAQSHLVVAHLWSLDATPSATGDQFAATQQVSFYSLLALAQALGQVSLAGAPEIAVVCAAVHSVIGTETINPDLAAILGPARVIPQELQGVGCRTIDLALPQRGSAEERELLDLLARELLAQSGEPIVAYRNNQRWVAAYKPVHLEAPARTALREHGTYLITGGLGDIGLILAEHLASTVRARLVLLARSELPDRGEWPRWLSDRSEDDRTCQRIRAVQRLEELGAEVLTITADVADESALRAAVDRATERFGDIHGVIHAAGIVATAAFRSVQDSDPAICEQHFQPKVHGLYALERVLGDRSLDFCVLFSSLSSVLGGLGFSAYVAANSFMDAFAHRHNQSHPVRWLSVNWDLWLGSVDKTMSGGLGASLTEYGMTPAEGVAAFERVLSVRDASQIINSTGDLDARIAQWVRMEALAVGADAPTPAAKLAHARPELNTAYVPPRGEYEQRIAVIWQEALGLDQVGIQDNFFDLGGNSLVGIQVIARLQKEFKVQLSTVVLFEAPTISALATYLMERLPQVAGVASQPQPARRQQRQAAQGDIAIIGMAGRFPGASSVDELWRNISQSHEAFSIFSDEELLAAGVAPALVRDPNYVKRRPILGDDIGLFDAAFFGYSPREAEFMDPQQRLFHECAWEALETAGYDSQRYDGLVGVFAGASVSTYMLQLAALPVFNDFGSDPSAYFSNDKDGLTTNVSYKLNLHGPSVAVQTYCSTSLVATHMACRSLRGGECDIALAGGVSVRVPVKTGYLYRDGDQVSPDGRCRTFDAEAGGANFGDGVAIVVLKRLADALADGDTIHAVIRGSAINNDGGLKVGYTAPSVVGQSKAIAAALDDAGVTADSISYVEAHGTATKLGDPIEIASLTKAFRASTDKVGFCGISSVKPNIGHLDRAAGVTGLIKTVLALKHSLIPPTLHFHAPNPEIDFAASPFYVLTEPTPWTRNGTPRRAVVNSLGVGGTNAHVVVEEAPPAPAANPSRPTQLLLLSAKTPTALEAAAARLSDHLGGQDVNLADVAYTLQVGRRVFEHRCVMVCEDATDARSLLTKGDTRRVLSRQQKPTSRNLAFVFAGVGDHYAGMAQGLYETESVFRATVDECFRILTPLLGADLKQALYPEGQARRNGNGSGIDLRALLGRDRAAGGAAGPLHQTALAQPAVFVVEYALAQLLMTWGIRPHALLGYSLGEYVAAAVAGVLSLEDALALVARRAQLIQALPSGAMLAVAAGADAVRPYLGGEVCLAVVNSPSTCVLAGPQQALAAVADQLEALDISSRWLETSHAFHSTMLASVQAELTAFAATLTFHLPTIPYLSNVTGTWITAEQATDPGYWAAHMCQTVQFAASVAVLAQDANRVMVEIGPGQALGSFVKQSPAWGRDRLDLVLSTLPSQHEGLSDSTALLTALGRLWLLDVPIDWQEFAVGEQRRRVPLPTYPFERQRYWLEPSRKVGGLAEQSDKLDLMGLPRDPANEWFYLPAWKQSAPYLPALATSSDDSPQCWVIFEDACVVGQQIGACLRQQGQHVVSVHAGAAFFKNGDSYTINAGQRADYDELFNDLYQQNRRPTNIVHLWTVTPPLPHPLPDRLLGPVLDASFYSLIHLGQALGDLDLEACTITVVSSDMQSVIGSERQCPEKATLIGPCKLLQFEYAALGCRSVDIVLPERGSWEEEALISHLLGELTAATADTQVALRGNRRWVHSLDRLKLAAQESSAPRLRKHGVYLITGGLGGIGLALAEHLARTQQARLALVGRSGLPERSEWPALLARQPEHAHAGKIRQIQAIEALGGEVLVLRADVTDTGEIEAAVAQTIERFGSLHGVLHAAGVPGVGLISLKTRETAASVLAPKVQGTRALAHALNNMPLDFLALFSSVASATGGGAGQVDYCAANAYLDAFAHSRAGQPSLVVSIGWCEWLWNAWDEAMSSYDSATQEFFRDYRERFGLRFDEGSQALDRVLSHRFPNVFVSTQDLRAIVRMMENAKIDVLEQPEAQGARHARPSLGTSYVKPQSKLEQAIAAVWSERLGIAEIGLNDNFFELGGNSLIGVDLLNRLRKRLQISQIPAYVLYEAPTVGAMAKFLEPGQDTNAAIQERHDRGAKRRDRQAQLKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV86</accession>
    <name>A9AV86_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0515"/>
    <dbReference type="EnsemblBacteria" id="ABX03164">
        <property type="protein sequence ID" value="ABX03164"/>
        <property type="gene ID" value="Haur_0515"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0515"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_3_4_0"/>
    <dbReference type="OMA" id="IIKDTHR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-523-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="256" mass="28691" checksum="A7FAB02F255CBDDF" modified="2008-01-15" version="1">MGDDVLGLIILLLIIITITAIRFFPASIIYEHERGLLYKHGKFQRVLEPGKYRFLRNAYQISKIDVRPSSLSLSGQEMFSADLISVKLNLLANFQIDQPDRWTHSHISAQTVVYNELQVALREVIAGYTLDQLLADRSMIAPQILALVQPKANELGASIQTIQIKDFSLPAELKRAALQQAKVQRETAAALEQARGEQAVLRSLANAARMLERNPALMNLRVLQALDSNKSNTIVLHVHQSNNDQTIDSEFTQPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA0</accession>
    <name>A9AVA0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0530"/>
    <dbReference type="EnsemblBacteria" id="ABX03178">
        <property type="protein sequence ID" value="ABX03178"/>
        <property type="gene ID" value="Haur_0530"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0530"/>
    <dbReference type="eggNOG" id="COG2976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768973_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-539-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029050">
        <property type="entry name" value="Immunoprotect_excell_Ig-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="360" mass="39163" checksum="87D780721DA114D2" modified="2008-01-15" version="1">MSYPQPSMPPYMQPVPPNKPGWRKNIKWIAIGSVVFVCSCLGLAYNQGSKLQAEQTATAIVVANVTATAQQSNTNATSEAVAIAATVEQDNANATKEAIAIAATQTEEARPTNTPVPTNTPLPPTATPFVAEIGQSNPIGQWEITILDISIANDFSEAATGKWLVVHGTITNKGDDHLIGKQELKVRTDTKTIELDRNASNQAAKRLNVTSIGDLGGKMIKRGEREEWAIAFDIPQDSNELWFTLEGTDAVKFGAIGETAELPTVTPRPTATAVPDLATEAGAIDVCKQAVKQRLTHPSTADFPWFDYQTVQEGDLTWYVQSTVKAKNSFNLEVEFVWVCKVTYEGNSRWNIDDVQMAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVD7</accession>
    <name>A9AVD7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1985"/>
    <dbReference type="EnsemblBacteria" id="ABX04628">
        <property type="protein sequence ID" value="ABX04628"/>
        <property type="gene ID" value="Haur_1985"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1985"/>
    <dbReference type="HOGENOM" id="CLU_615067_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2014-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="445" mass="49171" checksum="65F125A1937D0CDE" modified="2008-01-15" version="1">MINALWRMWWRLLFNPALVAKALMERQYAPKVLLVLGLVVDSLLLSVLLLWLNLGMVLWLILLKLVFTVISTCVACMVLTKQVPSDYLPRFLFWFGLFQVVLSPPLLVVVGVGGMLGLSLVGSASGAQAVIFCLMLGYLVGIALSYYLLINQQRRGSVDVRWAVLGIAPATALGIWYSPAFANSLAIFFAPIILGLGVAQLRLVMWLGQVGLGWVLQRIGVRAQLLTWHPIQFDALRLLPLPGTTNLLHMAAQQQPTLASDWIVARSQHLVDRWLVIRFLQDYATNPNAHRLFFALSLTQAGAELLAASIAGRDCNLNQCYARLAAVQAPGAWLNELATSGLGLAATAPMQLDPGLKVLLPLAFELLLARRWADAALILQETRIPSTEVAWLKQLSELRSMWVDNAAPAIQPPELQHESEQIWPNRLMLTLADHVSFLKEAESLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM0</accession>
    <name>A9AVM0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LAO/AO transport system ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3988"/>
    <dbReference type="EnsemblBacteria" id="ABX06620">
        <property type="protein sequence ID" value="ABX06620"/>
        <property type="gene ID" value="Haur_3988"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3988"/>
    <dbReference type="eggNOG" id="COG1703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043725_1_0_0"/>
    <dbReference type="OMA" id="DWRPPIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4030-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="42"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="34801" checksum="539FC80672B8324B" modified="2008-01-15" version="1">MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLVTQMALHWRSLGRTVAVLAVDPTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGLSRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTVVVVEVPGMGDDIQAIKAGILEIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAVERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDPYAAANQAIESVLEFPQSATPSGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS5</accession>
    <name>A9AVS5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4043"/>
    <dbReference type="EnsemblBacteria" id="ABX06675">
        <property type="protein sequence ID" value="ABX06675"/>
        <property type="gene ID" value="Haur_4043"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4043"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031866_2_0_0"/>
    <dbReference type="OMA" id="YPTGSWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4086-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="48"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="47490" checksum="571E5BA1679D53D8" modified="2008-01-15" version="1">MSTQAMVQLRITPGRPAVAQSNDPQIVYLLVEASPAGIPDADLAIPVNLGFIVDRSSSMRGERLYQVKEACNNVVNQLNRQDYFSVVSFNDRAEVVVPCQRPNDKDQIKRAIGMIEAKGGTEMATGMMMGLQEISRPMMSRGISRMVLLTDGRTYGDESRCVEIARRAQSKGIGITALGIGDEWNEDLLETIASAENSRTEYITNAQQIVNVFSDEIKRLQNVMAHKVEMRFHLHPQAEIRSLFRVRPFIAALTPQLHNETLWRMPLGEWVGREDQIFLLELVVPPLPAGNQTICRIEMFYEVPSISSQALQTKVDVQLPVRPAEQIRPDVDGVVKHWLERTVAYRLQASAWQHVEQGNIEEATKKLRMAGTRLLESGQTELAQTVQEEATRLLRSGTTSDEGRKRIKYGTRGLVARERGGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX0</accession>
    <name>A9AVX0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0560"/>
    <dbReference type="EnsemblBacteria" id="ABX03208">
        <property type="protein sequence ID" value="ABX03208"/>
        <property type="gene ID" value="Haur_0560"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0560"/>
    <dbReference type="eggNOG" id="ENOG502ZTFI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1141342_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-569-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="26338" checksum="75D1D5F1E7684465" modified="2008-01-15" version="1">MVRFFRSVKLFTADNGGGGSGSGNGGNPPPANPPANPPANPPASGGNQPDIAGQIANLIARQGSPDAALMLLMQENYQYRDQNRQLRERVPDGAVVLSGDDVQRWRDYQALGQLDELRTRLTEREQAQTELATLRTQATMRTVAEAMQWKPSVLERLAGNVTFITKTEGDKTTITVKDGDGETPLDAYAEKHWGEFMPALTIDSNPARRGTGFVHQGGGNPKKDDPITTHNQRMGYSLPKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ1</accession>
    <name>A9AVZ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0581"/>
    <dbReference type="EnsemblBacteria" id="ABX03229">
        <property type="protein sequence ID" value="ABX03229"/>
        <property type="gene ID" value="Haur_0581"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0581"/>
    <dbReference type="eggNOG" id="COG3440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075532_0_0_0"/>
    <dbReference type="OMA" id="CSLHHKL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-590-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011396">
        <property type="entry name" value="UCP030850"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030850">
        <property type="entry name" value="UCP030850"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="202"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="37290" checksum="9518DA64920FC6AA" modified="2008-01-15" version="1">MLAQYQRAFEKLKLSPSQAWPESTHFRAPYKPLMLLAVSDLISVGTLTHNFIEYSEFLLETFDRYWRIIFDSTKFANPIQPFFYLKSEGFWHLQAQPGMQQRLAATKDIKTINQLNQLVLGATLDQALFELLQQPFARTQLRQSLIQQYFTPELWTALGMIAQINTEIFDYSKLLIEQSQRMFREIPATDAPYQVEVRSSAFRQIVVPSYDYCCAICGIRVITPEGRSAAEAAHIIPWSRSYNDDPRNGVALCGLHHWVFDQGLLTITPSYKIQISPLVDDQPPANQTLLAFTRQSIQLPNQAHLYPNPIALNWHNQFVYRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ6</accession>
    <name>A9AVZ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0586"/>
    <dbReference type="EnsemblBacteria" id="ABX03234">
        <property type="protein sequence ID" value="ABX03234"/>
        <property type="gene ID" value="Haur_0586"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0586"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_923441_0_0_0"/>
    <dbReference type="OMA" id="LANHRMI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-595-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="159"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="32604" checksum="CAA8435811AA0B22" modified="2008-01-15" version="1">MLRLFSAIQLGTLELTNRLVATPSPSRFSHGGGFLNRSLIVEYGRWSSYGIGLIISEPVLVQANSNLPRPALSADAHIQAFRNLNQCLHEYQSHCLPLLSLVSQPESQLQPSNWPTLREQMVLAAWRAYAAGSPGIVIDANAGSLFHQLRVSKQVPPTSRSQLLLEIIEAIRGWLGRQFVVGVRLVVDDLVPDGVSLQESRVLAHELVAAGVDLLDLVVGRSVAPIAQFPGWQIPLVAGIRSIVDVPLIAHGMLGDPWIAEEMLREGCADLVGLEAAISATPHWPIWARQQLEREAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW14</accession>
    <name>A9AW14_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0604"/>
    <dbReference type="EnsemblBacteria" id="ABX03252">
        <property type="protein sequence ID" value="ABX03252"/>
        <property type="gene ID" value="Haur_0604"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0604"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="DNPMNME"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-613-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="13827" checksum="1A2693DF9B4C2F3E" modified="2008-01-15" version="1">MHILLVEDHEMNRDMLKRRLERRDFQVSVAVDGQEAIDLVESLMPDIILMDMSLPNVDGWTATRIIKANPAVNQIPIIGLTAHAMAGDRERCLEAGCNEYEIKPVDFTSLVSKIQALVEDTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW29</accession>
    <name>A9AW29_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0619</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0619"/>
    <dbReference type="EnsemblBacteria" id="ABX03267">
        <property type="protein sequence ID" value="ABX03267"/>
        <property type="gene ID" value="Haur_0619"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0619"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_1_2_0"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-628-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="17"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23541" checksum="1D93DD883D6C9140" modified="2008-01-15" version="1">MSHPELNPILHNQAPVPLLVIISGPSGVGKDTVLMRMREFGMPFHFVVTTTSRGQRPGELEGFDYNFVSKAEFETMIAQNDLLEHAVVYGEYKGIPKSQVRDALASGKDVILRIDVQGAATMRKLVPDAVLIFIVPPSSAELANRLRLRRTESAEGLERRMALAEEEMGRVDEFDYVVMNPESRPDEAASMIQAIIRAEKSRIRPRRIKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW39</accession>
    <name>HUTU_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urocanate hydratase</fullName>
            <shortName evidence="1">Urocanase</shortName>
            <ecNumber evidence="1">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutU</name>
        <name type="ordered locus">Haur_0629</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="1">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the urocanase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AW39"/>
    <dbReference type="SMR" id="A9AW39"/>
    <dbReference type="STRING" id="316274.Haur_0629"/>
    <dbReference type="EnsemblBacteria" id="ABX03277">
        <property type="protein sequence ID" value="ABX03277"/>
        <property type="gene ID" value="Haur_0629"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0629"/>
    <dbReference type="eggNOG" id="COG2987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018868_0_1_0"/>
    <dbReference type="OMA" id="LVGDWAN"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01228">
        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0369">Histidine metabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000129564" description="Urocanate hydratase">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="172"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="269"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <sequence length="552" mass="60031" checksum="78FED0E1A8F2F534" modified="2008-01-15" version="1">MTSSRIVRAPRGSELSCKGWAQEAALRMLMNNLDPDVAEDPQNLIVYGGTGKAARNWQCFDAIVRSLQELNDDETLLVQSGKPVAVFRSHRDAPRVLIANSMLVPHWATWENFRELEQAGLTMYGQMTAGSWIYIGTQGILQGTYETLAAIARQHFGGSLRGRWTLTAGLGGMGGAQPLAVTMNDGVALVVEVDRQRMQRRLDTRYLDVAVDTLEEAMTLVDEAVRDGKALSVGLLGNAAEVFGELYKRGVRPDIVTDQTSAHDPLEGYVPAGMSLEQALELRQRDPEEYVKHSTASMVEHVKAMVAFADAGSIVFDYGNNLRGVAKAAGYDRAFAYPGFVPAYIRPLFCEGKGPFRWAALSGDPADIAKTDEALLELFPEDQALHRWIRAAQERVQFQGLPARICWLGYGERAKAGALFNKLVRDGVVSAPIVIGRDHLDCGSVASPNRETEAMRDGSDAIGDWPILNAMINAVNGATWVSVHHGGGVGIGYSLHAGMVIVADGTAEADHRLERVLTSDPGMGVVRHVDAGYDEAIAVAQERNVHIPMLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX48</accession>
    <name>A9AX48_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2216"/>
    <dbReference type="EnsemblBacteria" id="ABX04856">
        <property type="protein sequence ID" value="ABX04856"/>
        <property type="gene ID" value="Haur_2216"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2216"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_968996_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2244-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731698" evidence="2">
        <location>
            <begin position="24"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="30476" checksum="9671F35A042152F5" modified="2008-01-15" version="1">MKPRLATWLIALGWLLIGCGAQTPPGSDQTAPTPSRPILGLITPSLAQTVSIQTPVATQQPTPAITAVACQKPSTWISYTVLLNDTLSELAYRSGTSVEQLQQVNCLNDTLIFAGQQLYLPTLSSVEPTNDVAAPAEPSSEPSPNPDLAAIATRTIDIPIPSGPNDQLLISPSLGIAGTSFSLHYQKFEPNANINYTIYNEDFAIVATGELMADATGKITFVYVSPVDTPSGFYLVEMQSQTVWAEASFEIIESSTLPKASPEPTSTKASPSPSTTPIDITLTPNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX90</accession>
    <name>A9AX90_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase M3A and M3B thimet/oligopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4178"/>
    <dbReference type="EnsemblBacteria" id="ABX06810">
        <property type="protein sequence ID" value="ABX06810"/>
        <property type="gene ID" value="Haur_4178"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4178"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030403_3_0_0"/>
    <dbReference type="OMA" id="CAFQFWK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4225-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="160"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="561" mass="63782" checksum="AFBB89EB58BD60EC" modified="2008-01-15" version="1">MSLKIDPRDWATVQPYYDSLAAEELTAANATAWLGRWSELEAHLQEFGFKAYRAMTENTQDQAAEELYLYTIEELTPKSKVAAQTLKEKILALDPTLLPAKMQEMLRRFHAEANLFREENVPLLTEVERLSAEFSKLMGAMSVEWQGETLTMQAVVKLFSDPDRSVREAAFKAYHSRFLQDRAAFNEIYLKQLKLRRQIATNAGKASYLDYVWDLYGRFDYTPADCRTFHDAIEHEVVPLVEKWLAVHQAELGVDSLRPWDILVDSQSRPALTPFQSADELESVCQTIFDRVDPELGAQYTRMRDGWLDLDSRPGKAPGGYCGGMFVSKVPYIFMNAVGTHDDVQTMLHEGGHAFHFMESSATNDLIWNYDGPTEFCEVASMAMELLAAPYLANAKGGFYSETDARRARAEHLWSMLKFLPYMATVDAFQHWVYIEAPEDVTAEQLDAVWKDLYQRFMSGVNWDGFEDVQTTGWHRKQHIFEAPLYYVEYGLAQLGAQQVWRNALADQAQAVAQYRAALALGNTKPLSQLFAAAGAKFAFDRATVGELARLVDQHLTTLRD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXD9</accession>
    <name>OBG_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase Obg</fullName>
            <ecNumber evidence="1">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">obg</name>
        <name type="ordered locus">Haur_4227</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXD9"/>
    <dbReference type="SMR" id="A9AXD9"/>
    <dbReference type="STRING" id="316274.Haur_4227"/>
    <dbReference type="EnsemblBacteria" id="ABX06859">
        <property type="protein sequence ID" value="ABX06859"/>
        <property type="gene ID" value="Haur_4227"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4227"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_0_0"/>
    <dbReference type="OMA" id="VVFDWEP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000385979" description="GTPase Obg">
        <location>
            <begin position="1"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Obg" evidence="3">
        <location>
            <begin position="2"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="1">
        <location>
            <begin position="162"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="2">
        <location>
            <begin position="355"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="168"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="193"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="214"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="284"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="316"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01231"/>
        </source>
    </evidence>
    <sequence length="437" mass="47945" checksum="F990FF02BCB088FF" modified="2008-01-15" version="1">MSDFIDRALITVKAGDGGDGMATFRREKYVPRGGPDGGDGGRGGSVYLEVSPHLNTLLPFRFETHFEADKGLNAGRQRKRGRTGEDTFIRVPPGTIVSAEIEGEVQTVDLLFPGQKLLVARGGKGGLGNTHFATASNQVPRIAELGQPGEERELQLELKVIADVGLVGFPNAGKSTLLSMVSAARPKIANYPFTTLSPNLGVAEFNDFTFVVADIPGLIEGASRGVGLGHDFLRHIERTRILVHVLDAAGTEGRDPFEDFLTINAELKAYSSELAQRPQLVALNKTDIPDAEAFDELMRPQIIAWGIDPENIFPISAATNQGLQPLQRRIVDILREMPERITRLPYSEEILTFRFSNIDPNDFWLETEEDGVLRVHGEKIERLVSMTNFAQSESLERLQRVLEAMGVSAALFAAGVRHGDPVRIEKAELLWQDESIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE7</accession>
    <name>A9AXE7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4235"/>
    <dbReference type="EnsemblBacteria" id="ABX06867">
        <property type="protein sequence ID" value="ABX06867"/>
        <property type="gene ID" value="Haur_4235"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4235"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029703_1_0_0"/>
    <dbReference type="OMA" id="WIVPLER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4282-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="536" mass="60875" checksum="889236BB0DABBE62" modified="2008-01-15" version="1">MRFLLDARSYDEMKARNDHTPDCYVRPGEYLHHMYVDGIKYAVARALYDCLKEAREKNDYEATRHLNMHKQQLDALVAEAQASGKLSGARVLGGDVPNDDGSAPSGNSYHPQVPTTIEETGLNRTQIQDQLLRVIYNRSRVTGMELAQEVRLFYSVVDPVITQMRNSEYIDIAGQRGFGDTNYEYILTPRGSQAAEDAMKKSNYSGPAPVPFAQFLESVKAQTIKNMVITRRNIRKAFSDLIITDQVLNEVGPAVNSGASIFLFGYPGNGKTSIAERITRLMGDDIFVPYAVDADGQIIKVYDSIVHTLVDKEANIGTSAYDLRWAKIKRPVVVVGGELTLEALDLTFNEAGRFYEAPFQMKANGGIFLIDDFGRQQCRPMDLLNRWIVPLEKRYDYLTTITGQKIEVPFDQLLIFSTNLDPSQVADEAFLRRIKFKIEVRDPDESQWRQIWSLVCKGRKINLDPKGLDYLVEKWYKPDDRPFRMCQPRDILDQMISIAKYNMEQVTFNPDLIDAACGTYFVSKEAKNFGAKVRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH5</accession>
    <name>A9AXH5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="9">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cysS</name>
        <name evidence="11" type="ordered locus">Haur_4263</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4263"/>
    <dbReference type="EnsemblBacteria" id="ABX06895">
        <property type="protein sequence ID" value="ABX06895"/>
        <property type="gene ID" value="Haur_4263"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4263"/>
    <dbReference type="eggNOG" id="COG0215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_0_0_0"/>
    <dbReference type="OMA" id="GWHAECA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1e" evidence="10">
        <location>
            <begin position="20"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="396" mass="44445" checksum="9FDCB9A011B5DB2D" modified="2008-01-15" version="1">MLLYDTLCQTPVAMEPIDGFVRMYVCGVTPYDTTHMGHARTYVVYDTIRRYLEWQGLPVLYVQNVTDIDDDILRKSAQLGLTWDELGRQETERFLRDMDALNVRMPNHYVKATDAIAKIIEVNSGLIERGVAYENQGNVYFNVHADPDFGSLAHSDYASMLAIANERGNFPDDPHKRDPLDFVLWQATKPGEPWWDSPWGRGRPGWHIECTAMVLEYLGPQINIHGGGSDLQFPHHACELAQAENFTGQSPHVAAWSHIGMVYYEGEKMSKSLGNLVLASKTLQHYSADAIRLGLLKYYYRDQFEYSNDDVAWGERTVERFKQAVNSGVSGGALHAEELRNEAIAALDADFQTPACLQALITLAEASINGEIDDAELAATTLRELGAVLGLRTELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU4</accession>
    <name>A9AXU4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2270"/>
    <dbReference type="EnsemblBacteria" id="ABX04910">
        <property type="protein sequence ID" value="ABX04910"/>
        <property type="gene ID" value="Haur_2270"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2270"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015278_1_0_0"/>
    <dbReference type="OMA" id="MHTDPGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2298-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="618"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="748" mass="81904" checksum="452C4656913C29A2" modified="2008-01-15" version="1">MNHRWLRSRLLIVFVILGLGLGYLPLPSFANSPNPAASNLHMAFTAAAAEFHVPSEVLLALSYNLSRWEHHAGQPSTSGGYGIMHLTQIDLSHWHASKGLDWATLLKQPDELQTLTQAAKLIGQPPSTLINDPVQNIRGGAALLAEYSRSINPRLPNNLADWYGAVVLYSGGKERSTAFGFADRVYATLQQGATRSLDNGEALTLAPSTITINRQSAASLQLYLGDDFPLDCPTTLNCEVIPAAYALNNPNDRSDYGNYDLANRPADGLDFRYILIHDTEITYTQTVNVFQNPATGASTHYVIRASDGHIAQMVENKNVPWHAGNWDVNGHSIGIEHEGIAIEGATWYSEAMYQASAQLTRYLADKYQIPLDRSHIIGHDELPGPLPQHQAGMHWDPGPFWDWAHYMDLVRGGPAPISNPDPQLVTINPNFDSNMPALTYCYSSNDCRDVPTQSANFLYLHTQPNANSPLITNQYIGSTPTHANNWSNKVVTGQTYVVADQQGDWQAIYFGGQKAWFHNPDGSNTTAGQGLKVRPKVGQATIPVYGRAYPEAAAYPQGISPQAITPIYSLPADNMVVATQLYTSTYYYSPVYTPTLDPSSHIVVSGQTKYYQINFNHRFGFLKASDVEVQSSVLSLTTPKLAQSNLHGTSITYTLTLRNLSQQTVPISLNLIGNTWLTTITSAMPNDLGPNASQTITLRVDLPAGPSPAADQVWVKAQTSADPERSAVLLLHSSAETNINFLPLITKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY66</accession>
    <name>A9AY66_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4316"/>
    <dbReference type="EnsemblBacteria" id="ABX06948">
        <property type="protein sequence ID" value="ABX06948"/>
        <property type="gene ID" value="Haur_4316"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4316"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117563_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4368-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017255">
        <property type="entry name" value="AcTrfase_GNAT_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037663">
        <property type="entry name" value="Acetyltransf_GNAT_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17185" checksum="2F7DE7C7D1423274" modified="2008-01-15" version="1">MRAMSEADFLSIQAVIDDWWERPLSSLLQRWMCHYFSASSFVIEQDGKLVGFLIGLIDQTKAEAYIHMVGVAPELRRTGLAQQLYEKFFTLAISQQCRTVRAITAPVNQRSIAFHRRMGFALELGDGEAEGVPVVLNHAGPEQARVCFLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI4</accession>
    <name>A9AYI4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0918"/>
    <dbReference type="EnsemblBacteria" id="ABX03566">
        <property type="protein sequence ID" value="ABX03566"/>
        <property type="gene ID" value="Haur_0918"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0918"/>
    <dbReference type="HOGENOM" id="CLU_1022209_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-932-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022291">
        <property type="entry name" value="Bacteriocin_synth_cyclodeHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03882">
        <property type="entry name" value="cyclo_dehyd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="29795" checksum="4C61A489F4D08433" modified="2008-01-15" version="1">MDQLYSTLVATHQQWLFAQGLHENRSARLLLVTDAVMAQALLARLGQLPLAQVTVAALSSADHGPISQQIRELTSTFPIQLLARPFAAGGLGLLLSRYHAAALITQRPYPVVAEALNQASLRAATPWTALSLWGAQITLGPTILPNHTACYACYQARLRSCETRNDVWQARDGFLRRQQQALFQPSLAALNQLAASYGLVEIERLLLGQQPPLALGREVQWDTFNLGVSRNHVEPFENCSACGGQQNTTWIGRDQLAQVVAKLSLQAREVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYM9</accession>
    <name>A9AYM9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2367"/>
    <dbReference type="EnsemblBacteria" id="ABX05007">
        <property type="protein sequence ID" value="ABX05007"/>
        <property type="gene ID" value="Haur_2367"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2367"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_39_0"/>
    <dbReference type="OMA" id="RDINEIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2395-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="227"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="48393" checksum="05519622864296E6" modified="2008-01-15" version="1">MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGIGLALFTALVYLPHAHWLDAHAANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALHVYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALVQLPQTNGYSEIQINQIALAVRRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVRATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEFVATCQPLAAEYGVDLHLTITDDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLAVAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGLALVARSVAEHSGSIRLEPAPDRGTLARLRLPLVNQGAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY5</accession>
    <name>A9AYY5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4393"/>
    <dbReference type="EnsemblBacteria" id="ABX07025">
        <property type="protein sequence ID" value="ABX07025"/>
        <property type="gene ID" value="Haur_4393"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4393"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_0"/>
    <dbReference type="OMA" id="DYYWGMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4447-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="269"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="41075" checksum="E7A809BFBF297BC4" modified="2008-01-15" version="1">MNEAVIVAGARTAVGKSKRGMFRNSRPDDLAAAAIKAVVEQAPGLDPREIEDLILGCAMPEGEQGLNMARIASLRAGLPIDVPAQTVNRFCASGLQTIALGAERIMAGGADVIIAGGAESMSMVPMSGNKFAPNPWMAEHYPEIYINMGLTAENVARQFNISREDADAFSYRSHMKAIEAIQAGRFADEIVPVDVEFAEAEAGGAIKRSTATVKVDEGPRRDTTLEGLAKLRPVFHAKGTVTAGNSSQTSDGAAAVLLMNRQKADELGLKPLARFIGFAVGGVGPEVMGIGPVVAIPKVLKKTGLNLSDIDLIELNEAFGAQALAVIRELGIDESKTNVNGGAIALGHPLGCTGAKLTVQIINELRRRNGRYGMVTMCIGGGMGAAGIFELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZM4</accession>
    <name>A9AZM4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3 7">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">leuA</name>
        <name evidence="9" type="ordered locus">Haur_4446</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4446"/>
    <dbReference type="EnsemblBacteria" id="ABX07078">
        <property type="protein sequence ID" value="ABX07078"/>
        <property type="gene ID" value="Haur_4446"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4446"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_0_1_0"/>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="555" mass="59740" checksum="BEFB1F77EC02A2BE" modified="2008-01-15" version="1">MTSDYVRIFDTTLRDGEQSPGCTMHLHEKLEVAKQLARMGVDIIEAGFPAASPGDWEAVNQIAKSVGTADGPVICGLARAVKSDIEACATAIAPAAKKRIHTFLSSSDIHIEYQLRSTREEVLTKTREMVRLASSLCDDVEFSPMDATRSDIEFMYQMLAIAIEEGATTLNIPDTVGYSTPEEYAALLRGIIENVPGAADVIISTHCHDDLGLAVANSLAGVRAGARQIECTINGIGERAGNASLEEVVMALETRKQFYGLSTNIDTTQLTPSSRLLSACTNTQVPPNKAIVGANAFAHESGIHQDGVLKHRMTYEIMSAESVGQDGNALVLGKHSGRHAFRHRVQELGYSFDEATINHLFARFKDVADRKKYVDDRDVEALISDEAGRPSPVYELEHVQFASGVNAIPTATVRMRGPNGEVKIESAQGTGPVDAVYSAINKVVLTPVTLLEFAVNAITEGIDAVGEVSVKVVEGKHKHVRGVLTDKATDAKVWRGNGVNVDIIVAAAEAYVSALNKLLKARQERLKQETTARMEVASAAPGVDLFGGSTLGRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ6</accession>
    <name>A9AZQ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07110">
        <property type="protein sequence ID" value="ABX07110"/>
        <property type="gene ID" value="Haur_4478"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4478"/>
    <dbReference type="HOGENOM" id="CLU_249233_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4533-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735361" evidence="1">
        <location>
            <begin position="32"/>
            <end position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1489" mass="164126" checksum="20BED9D787E12F23" modified="2008-01-15" version="1">MRKRMRPKSRLLLLFIGFASLLSSLPTTLTAAASPHSITTTNASDDYQILISGQTLTELSIEPATDHDYFYIDVNAGQTITVVMVRTSADQALNGLLDLFDPTGAMIASDDNSGHRGNPLIQEVEAITTGRYMLRVRDYSGTRTGTYQITATVAEPLVSGPSFAITDLETDPCPLPMAAITVPEIADPTTGPKNPQFEIGNQALPRTGYPLNCEFARDRQILATAITPTAFTIQNAGQVQTTDAFVVDSSAQYLLFDYMVGRKTADKPTRLHVEVLSGPTFATITDLSQHTIRGQYLDGWKRGVLAVDAFRGQTIKLRFINDSSSAAQPSAQVRAIKLSIEVPDWQPSPVGTTAIEYNDSMGAHAVITGASAFLISAPFTIPLQTQSLSFNYQTGRRLNNASAPIEVQVLNGPDFITATPIDNNTVTGRLSDGWKRATLDIQAFRGQVVKLKIVNDWWPNEPQTTAIDSFKLNRAVPGWEVTNANYVSIESLQIPPSTLTNVLTNTDFEIGFTPIPDIIPNQTFELPSNPLQTLSFSTMSLNGTNVVTTTPPIVVPEQATSLQFEALIGDSSNPSLIKPVTVAILSGDAFDIRELPIDHQIRGTIQTGLQTAVIDIKRYQGKTIKLQFTNHTTNAPTSQLSNFRLVDHVPQWQANSQTRLNLINESSANPTHAFLVGTQSSLLSAPFTLPTEAQQIRFEYRTGHTDNATRQSRIQLTVLSGPDFGIRTRIDQNRLVGTDVIGWQSIAFDLQRFQGMPIKLEWVTELTNQPYLRLDNLQVGVAMTGWQASESSDILIEPTTPTLGQSMRINGNAATITSQPWTVLSNTVSLSFDYKVLRINETGNANLYVDVLSGHNFEVITRIDANGLVGSITTPNNGWQRATLNVSQFQGRTIKLQFKNAGYAMAQSWIDNLTLNHGQPSASHGSDEAPDGSFLTLLNTGTAQSALSSSFVVATDTQFLRFEYQTGTFEHGNEQRSFVVDILSGNNFATITTINQSLPSRSLNDGWQVAKLPISQFQGQTVKLRLTMPFVTKRSVVRIDKLALLSPRAQLTTPIAVDGTTYLNVPLTELGGITTTASMTITALVVYDEYVDLEGIVRYDNASYQLVSTGTTYRSMLGSPNDKVVDSIDQSNTFNLLHFAVRDNLPTTASLQQMAIADPVIALYLQKKNTRQLTAFEFSIDNTLLINELASAMARYDTDYYHDIWFKKIIKPYLIEDIDITDYSANTSNHSELLLKHRVRTKNIACEVIEEVVYAIVFNGDADIEKHQEHDIYSSIEIMYEQSSGKPINPNSNPAICDGYYDLPSSSSIQIGTIYPNPKQTLSVKIATYGTETNGEKADYLTRGRYNGSFYVEKKKYTPQIYLNAAVSLPKVPMLAFLTGNIASTVVSEGREEFVAKNQEKVFKHVFKGIIDLNSFATRSANHSFDYAVLDTAGYDANAFWGIKHWKGGRFSSSAMVSWHIPFTNNIYDAESHFSETNHTIIIYFMSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY6</accession>
    <name>A9AZY6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1045"/>
    <dbReference type="EnsemblBacteria" id="ABX03693">
        <property type="protein sequence ID" value="ABX03693"/>
        <property type="gene ID" value="Haur_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1045"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086998_0_0_0"/>
    <dbReference type="OMA" id="RMFITET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1062-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="275" mass="30891" checksum="159368770B8A7262" modified="2008-01-15" version="1">MSKQDDKMRIRNRLIDQAISEAANNQWEVAIELNRKAIEMAEDPETYNRLGKALQEVNRYAEALETYQKTLKLAPSNIIARRNIDKLTPLLSSEGKTNQRSRELVDLRLFVSETGKTGITTLTNLANPGLVSQLGSGEIVELRHEGRLLNAYTSDGILIGRIEPKLAQRLAELIDGGNKYAAAIAHIENGQVRIVIRETFQHPSQRTKISFPGKLSGDMGAFRPYVRDYSLRYDFDGDDDDEVDEMGEEEEEDLDEMSLDDVDSDDGDDDDELGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V0</accession>
    <name>A9B0V0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1172"/>
    <dbReference type="EnsemblBacteria" id="ABX03820">
        <property type="protein sequence ID" value="ABX03820"/>
        <property type="gene ID" value="Haur_1172"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1172"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_0"/>
    <dbReference type="OMA" id="DAAKPHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1194-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="36030" checksum="5123F0649751FACA" modified="2008-01-15" version="1">MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPYINEELVGEALEPFRNHVVIATKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEAIDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAGAQTIRRAHAVQPVAALQSEYSLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEALQANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLNEADLQAIEQAAASVNIQGARYPEDLEKMTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X7</accession>
    <name>A9B0X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03847">
        <property type="protein sequence ID" value="ABX03847"/>
        <property type="gene ID" value="Haur_1199"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1199"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_0_0_0"/>
    <dbReference type="OMA" id="DTHYGPI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="163"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="387" mass="42945" checksum="AB6144E2EAC0884F" modified="2008-01-15" version="1">MNILIISLFLLLYGGINSYIGIRTWQWLQSLVPRALPGWVKWVYWIGFAGLASAYFLLRFAASFMPASLSTILAQIGSYWWAIFVYAGLLLALVDLLRLILRKTKLLAAWKLRSQATLRMTGTVIFTIILTAIIYGTWRARTPVVTEYTLNIAKPAGSYRELSVVLVSDNHLGLINGNGRIQELVTMVNQLQPDLILIAGDLIDDDFKPFLDQAMASELSKLQARLGIYAIMGNHDVRDPELPSFRAELEQAGIQLLIDEWVVVDNSLVLAGRDDPSPPRAAGEGMALADIIANTDRSLPLLVMDHNPNRLNDTIAVEADLQVSGHTHAGQIFPFNLVTNMMYEEDWGALQRGSTHVVVSSGFGTWGPPMRIGTYPEVVHIQLTFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B130</accession>
    <name>A9B130_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ordered locus">Haur_2670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2670"/>
    <dbReference type="EnsemblBacteria" id="ABX05308">
        <property type="protein sequence ID" value="ABX05308"/>
        <property type="gene ID" value="Haur_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2670"/>
    <dbReference type="eggNOG" id="COG0261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_2_0"/>
    <dbReference type="OMA" id="HRQEITR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="13541" checksum="2D528910BD56D41A" modified="2008-01-15" version="1">MPLSFLSAADQTARRSGIVYAIIRDRGQQYRVEPGQTLQIALTDAEDGSTIEFNEVLMVGGSDTLVGSPLISGAVVKATVGEVVKGEKIIVFRYKAKARYRRRTGHRQKYTEITINDIVVPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B141</accession>
    <name>A9B141_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="12" type="ordered locus">Haur_2681</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2681"/>
    <dbReference type="EnsemblBacteria" id="ABX05319">
        <property type="protein sequence ID" value="ABX05319"/>
        <property type="gene ID" value="Haur_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2681"/>
    <dbReference type="eggNOG" id="COG0855">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009678_5_0_0"/>
    <dbReference type="OMA" id="NIKWARK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="22"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="137"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="341"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="513"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="574"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="695" mass="78792" checksum="8F2CC09C60F66F72" modified="2008-01-15" version="1">MTELLIPDTVAEPLNLADPRNFLNRELSSLAFHRRVLEEALDPSLPLLERVKFLAIFSTNLDEFFMIRVSGIRQQVAARVFERSADGKTPLEQLRAIRAAVAPLMELQRACFIQDLQPKLAAEGVFIQEYSQLSIHQQAWLKNYFDHEIFPVLTPLAFDPGHPFPHISNLSLNLAVVIQDPDSDEHFARIKVPASLPRLVSVPSEHPNTVCYTWLEQIIAENISTLFPGVQVSEAYTFRVIRNADVEIEEDEAADLLETIQAGVRQRRFGSVTKLSVHSTMPPRIVDLLIDNLEVERDDVYQLNGSLDLSSLMSVVRLDRWQLKLPPFKPSVPAVLSTGEDIFNVVQRRDVLLHHPYDSFMPVVDFLQAAARDPNVLAIKQTLYRVGSNSPIVKALLKARENDKQVAVLVELKARFDEENNIEWAKALEREGVHVVYGLMGLKTHCKVALVVRKERDGVSRYLHLGTGNYNAVTANIYTDLGLLTCNPDFGADASDLFNFLTGYSRQSQFRKLWIAPINLRRRLTHMIEREIQHQQAGRSGKLIFKMNSLVDPNIIQLLYRASQAGVEIQLLVRGMCSLRPGVEGLSETIQVKSIVGRFLEHSRLYYARNGGDEQLYVGSADLMERNLDRRVEVLFPIEDPSLLNYIREEILGVAWRDTAKARILLPNGLYGCHLPPAGEEPFDSQMYFLRRHTA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B148</accession>
    <name>TRPD_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="1">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trpD</name>
        <name type="ordered locus">Haur_2688</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B148"/>
    <dbReference type="SMR" id="A9B148"/>
    <dbReference type="STRING" id="316274.Haur_2688"/>
    <dbReference type="EnsemblBacteria" id="ABX05326">
        <property type="protein sequence ID" value="ABX05326"/>
        <property type="gene ID" value="Haur_2688"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2688"/>
    <dbReference type="eggNOG" id="COG0547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034315_2_1_0"/>
    <dbReference type="OMA" id="GPMTNPA"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="chain" id="PRO_1000099813" description="Anthranilate phosphoribosyltransferase">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="108"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <sequence length="338" mass="35004" checksum="8FD2645F46F1D737" modified="2008-01-15" version="1">MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQVMRAKSLAVPHDGGVVDTCGTGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGSADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMRYAGPVRREIGIRTIFNVLGPLTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRAGATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAALVACERADSFGEALRQAQQAIDTGSANQRMQRMIEASNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B159</accession>
    <name>A9B159_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2699"/>
    <dbReference type="EnsemblBacteria" id="ABX05337">
        <property type="protein sequence ID" value="ABX05337"/>
        <property type="gene ID" value="Haur_2699"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2699"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_10_0"/>
    <dbReference type="OMA" id="QWHSRRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2730-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="128"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="37039" checksum="313688C462A097B8" modified="2008-01-15" version="1">MSEIILVVDDEARSIDTLRRVLERERYTVRIARDGVEALADIQACMPDLVLLDVTMPVMNGFEVCRRLRDREETQLLPVAMLTGLNDDESRILGLEMGADDFINKPFERTVLLARIRSLLRVRRLTEELESTERVIFTLATTVESRDPYTEGHLRRLASYSYALATACGCDAKESRLIRYGGLLHDIGKIAIRETVLQKEGKLTSEEYDEMKKHPQIGANIVAPMRFSVSVGPMVLHHHERWDGKGYPHGIAGDTIPLGARIIAVVDSFDAMTTDRPYRKGMSRAEAVQVLQSGRNTQWQAELVDLFVELIEHGHVASDDLSWVLRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B164</accession>
    <name>A9B164_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2704"/>
    <dbReference type="EnsemblBacteria" id="ABX05342">
        <property type="protein sequence ID" value="ABX05342"/>
        <property type="gene ID" value="Haur_2704"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2704"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_5_0"/>
    <dbReference type="OMA" id="FFNRFAA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2735-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="33823" checksum="67D4364E020BA695" modified="2008-01-15" version="1">MILVTGGTGYVGSRLIEKLRQRPEPVRVLVRTPEKAQKLVAGNVSIVKGDVTDPESLIAAMKGVSTVIHLVAIIRERSGGISFERMNYQATVNVVDAAKAAGVKRFLHMSALGVVNDPNLPYMDTKFRAQKYVEASGLDWTVFQPSVIFGEGDEFINTLADLVRRPLMIAPAPFVPVVGDGKTKFQPVWRDDVIDAFIKVLDDHSTIGQIYQLGGPEALTYEQMLDLIMQKLGKKRSKIYVPVPLMKPAVFMMDKLLPKPPVTPAQLTMLSLDNSAPQSATEQLIGHRPLALGDGIDYIKKPNAARHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B192</accession>
    <name>A9B192_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4648</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4648"/>
    <dbReference type="EnsemblBacteria" id="ABX07279">
        <property type="protein sequence ID" value="ABX07279"/>
        <property type="gene ID" value="Haur_4648"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4648"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_0"/>
    <dbReference type="OMA" id="HNVISDG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4705-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="23920" checksum="B160AF42893DAC58" modified="2008-01-15" version="1">MRILIVDDHPVFREGVRALLETHDEMEVVGVLGHGRDAAVVAKDQFVDVALLDVSLPDMPGYEVCRSIVEASPRTRVLMLTANDTNDVIRQSLAAGAAGYVLKTEDPSRLISHISAVAQGETVLAGPIAQKVVRQLLEGPQPTVSTKTNDALNALTERERQVFFLAAEGRRNSDIAQQLILSEETIKTHLRNIYSKLGLGNKAELRLFAVQARLAPPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1C0</accession>
    <name>A9B1C0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4676"/>
    <dbReference type="EnsemblBacteria" id="ABX07307">
        <property type="protein sequence ID" value="ABX07307"/>
        <property type="gene ID" value="Haur_4676"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4676"/>
    <dbReference type="eggNOG" id="COG3025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040400_3_1_0"/>
    <dbReference type="OMA" id="THRREEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4733-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="CHAD" evidence="2">
        <location>
            <begin position="222"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="521" mass="59163" checksum="EBF5D98BF893991B" modified="2008-01-15" version="1">MEQEAKYRATQPIRPKQLEAINIAPFSLGERVTVEIRDSILDTASRQLDQQRYTLRIRRIDQQLWLTLKLPGKVKGAVHQRQEFEHEITPNVRDHPELWPSDIREPLQAVIGDEPLLPMLTVRNRRRLWRIERDGQEIAELALDRGSLVSGERSLPFHEIEIELKGVGTAADLAVLASIYTTQLPLEPETRSKSQRGMLLLNHAEHLEQLKQAVDRTPMESTNNLAEAGRSILAKHVLKLHKAWPIAVVGDDSEGVHQMRVATRRLRTILAILGETLYEPEIVAKLRRGLRQWASVLGAVRDADVFLGKLDDHRADLPEQEQAGYAPLIESISQQRDAARVELLSFLESRKASKFAQRLTDFVLTAGAGVREADTSEGRVERSLVRHWVGSTVWSHYERIRAYDVILNDAPVESLHRLRIEIKHLRYTLELFSAALAEEHESLLEQLVTAQDYLGDLQDAEVALAVVEQSLAENPENGALLAYQAAKQQEHDQLQLNAPKILRSLFDLPFRRRLASILSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I2</accession>
    <name>A9B1I2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1219"/>
    <dbReference type="EnsemblBacteria" id="ABX03867">
        <property type="protein sequence ID" value="ABX03867"/>
        <property type="gene ID" value="Haur_1219"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1219"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="IDDDSRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1241-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13643" checksum="1F5A1E8DC348BA5A" modified="2008-01-15" version="1">MSTTVVLYIEDNPDNMLLVERLLIARGCQMLKAINGSTGIELALAHNPQIILLDINLPDIDGYEVARRLRDAPQTATIPIVAVTANALKGDAEKAIAAGCDGYVSKPINLRDLWNAMLQFIEAPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L2</accession>
    <name>A9B1L2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1249"/>
    <dbReference type="EnsemblBacteria" id="ABX03897">
        <property type="protein sequence ID" value="ABX03897"/>
        <property type="gene ID" value="Haur_1249"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1249"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012705_0_0_0"/>
    <dbReference type="OMA" id="TEFGRGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1271-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="429"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="712" mass="76812" checksum="8CA51FFDBE2E2BED" modified="2008-01-15" version="1">MSRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGEMLITQQNGQLLGWNGTSTRTVMSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNKFNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLIDNIGSYNGNHNAGDLGFGKDGKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCNTGSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWNCREGTRVNNSTGPCSPTPANMVDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSGYMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGPNGGRQALFYATYANGGEIRRISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTYANNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQASDAEQGQLPASGLSWKVILHHDTHTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTATDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPIEADDPFISWENYSLRVTAPAYADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1M9</accession>
    <name>A9B1M9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1266"/>
    <dbReference type="EnsemblBacteria" id="ABX03914">
        <property type="protein sequence ID" value="ABX03914"/>
        <property type="gene ID" value="Haur_1266"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1266"/>
    <dbReference type="eggNOG" id="ENOG502Z8JB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_721150_0_0_0"/>
    <dbReference type="OMA" id="IPYEGVR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1288-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="383" mass="41228" checksum="09C52932813CC482" modified="2008-01-15" version="1">MTHYYPDGAAPVVMHTVARIERQLPVEGEVLVRVGSRVEPDDIVLRAQYPLDPQIINIARDLGVLPTQVYSKMKKEEGNKVAKGEVLARAGLIAGSTVVAPVAGTITTIDRSTGYVTLTPNALPIELKAQVRGIVMEVPDSRTVIIETPASYVQGIFGLGGERFGVLRLLVTDPKEQVDISSIDARSAYAILIGGASITAAALRRAIDEQVRGVIVGGIEEHELRDFLGDDGFDAWRTGYNTWRLPAPPYNRDPGLTLMITEGFGVQPMNEALFKVLASYDQQEALIEGVTQLRSPQRRPRVVIPLSRVRNIEQAAVVKASLAVGSPARIVAGPHRGTVGTVRSFPALPQLLPSGVRSHVVEITLSDGKQTLLPAAALEPLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N2</accession>
    <name>A9B1N2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1269"/>
    <dbReference type="EnsemblBacteria" id="ABX03917">
        <property type="protein sequence ID" value="ABX03917"/>
        <property type="gene ID" value="Haur_1269"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1269"/>
    <dbReference type="eggNOG" id="COG3287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052774_2_0_0"/>
    <dbReference type="OMA" id="FYCAGRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1291-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="34"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="230"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="387" mass="40201" checksum="D7F6F96E22F32D06" modified="2008-01-15" version="1">MTTHAATGASQIEHSYDAGFAAAQQACTQLAPHSPTCLIAFTTDAYDQAAVVQGIRAASQQAPLIGCCAGGIISNAGTFTHGVVLLALASDDLKLDLSLVAGVKADPGKVADQLADQLEAVLDNPTSQQAALILVDGLAGTLTDFVQHATAAFGPLCPLVGGGAGDSFQFKQTYQFVNDQVISDGAAVGLLQSPTPMGIGVQHGWEPAARGLVVTRSEGTIIYELDGRPAFAVYQELFPDLTVENFGRFVIDHPIGLPQINGEFLIRDPLRTHPDGSIECIASVPKNVVAHIMHGSHETLFNAAQLATKRALAALNGPPAALIIFDCVSRLAMLGDAAATEVQRIREVAGLDVPVVGMFSFGEIAAAETGGALFHNKTVVVYAIGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N4</accession>
    <name>A9B1N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1271"/>
    <dbReference type="EnsemblBacteria" id="ABX03919">
        <property type="protein sequence ID" value="ABX03919"/>
        <property type="gene ID" value="Haur_1271"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1271"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="WADAYIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1293-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15490" checksum="312B219ADBB6D492" modified="2008-01-15" version="1">MPPIQKAFVMVVEDNADNMWIITEMLNDDPRVRYCNVRPSGKQLFAFMAKNDVPPINLVLLDLNLPGDDGYSILEKIRVHPKLSNAIVVAVSADNTAEDVAKVRASGFDGFIGKPLRHDRFPEQLQRVMDGEAVWEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1P2</accession>
    <name>A9B1P2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-alpha-glucan branching enzyme</fullName>
            <ecNumber evidence="3">2.4.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1279"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03927">
        <property type="protein sequence ID" value="ABX03927"/>
        <property type="gene ID" value="Haur_1279"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1279"/>
    <dbReference type="eggNOG" id="COG0296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004245_5_0_0"/>
    <dbReference type="OMA" id="TQIDHDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1301-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="138"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="560" mass="63284" checksum="1827A342E60C35C6" modified="2008-01-15" version="1">MQNDANPDASPTVASLPDGVWMGARDLGNGAVAFGLYAPWKQSVHLIGSFNDWNQTADPLNISDRGIWWIIKEGLAAGEYAYQFVIDGETIIGDPYARELRWAGGDQPQAIIHVGEPAYEWHDDGFGIRPLNELVIYELHVGDFSEAGTFKAVTERIPYLQDLGVNALELMPLFEFPGDRSWGYNPAYFFAPESTYGTPADLRELIDTAHQHGIGVILDVVFNHVDHSSPINYLYPYDQSPFFSSDGNPWGFPDLNHWNEAVKQLISDVQTYWLSDMHIDGFRYDHAEGIGFDGENGVSFLGWQARQIKPHVYLIAENLKDYTTMVDQTDMDSSWHRSFHSQMFANLREGDFEGNQYGNVEATLGIIDFRNAGYNDNAQAINYLESHDEQRIVYEAQTNENISRETAYLKSRLGAIVLFTAAGVPMLYHGQEFGMDTERTIDKNMLKWELLQTAEGTDLHAFYRGMIQLRTSSKALVGNNIRPVAMDAERKLLAYYRWADDGSEHVIVVVNFGITLQYLDVHFPVGGLWHEWVYNYDRETPEGMATIEVPGSGGKVFVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1P5</accession>
    <name>A9B1P5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1282"/>
    <dbReference type="REBASE" id="16522">
        <property type="entry name" value="M.HauORF1282P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03930">
        <property type="protein sequence ID" value="ABX03930"/>
        <property type="gene ID" value="Haur_1282"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1282"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018284_4_0_0"/>
    <dbReference type="OMA" id="VWFYEHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1304-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="137"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="481" mass="54628" checksum="D38AF602EBEDF76D" modified="2008-01-15" version="1">MNLTTTIKSIQDIMRKDAGVDGDAQRIGQLVWLLFLKIFDDREQELALIDPHYRSPMPEGLAWHQWAINREGITGEELLNFVNNQLFPQLKNLAATNQAKAMIQSVFEDAYNYMKNGTLLRQVINKINEIDFNRSADRHLFNDVYEKLLSDLQAAGNAGEYYTPRTVTQFMIEMLKPRLGESLLDPAAGTGGFLVSAVEYIRRNDVHTPSDLETLQANIRGIEKKPLPHLLGITNLILHGINLPNLQHANTLARSYSSYGVDDQVDIIATNPPFGGQEEDGIENNFPELFRTRETADLFLVLIMRLLKPNGRAALILPDGTLFGEGIKTRIKEELLKNCNLHTIVRLPNGVFNPYTGIKTNLLFFEKGQPTQEIWYYEHPYPAGYKSYSKTKPIRLEEFEPERAWWINRQTNQFAWKVDIADIRANNFNLDWKNPNRQADAQTDPYQLLAEYQAATASAAQTRASLKAELVAALQALLELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q8</accession>
    <name>A9B1Q8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper-containing nitrite reductase</fullName>
            <ecNumber evidence="5">1.7.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_1295</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:15233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1295"/>
    <dbReference type="EnsemblBacteria" id="ABX03943">
        <property type="protein sequence ID" value="ABX03943"/>
        <property type="gene ID" value="Haur_1295"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1295"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031740_4_0_0"/>
    <dbReference type="OMA" id="PMLHHIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1317-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050421">
        <property type="term" value="F:nitrite reductase (NO-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001287">
        <property type="entry name" value="NO2-reductase_Cu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00695">
        <property type="entry name" value="CUNO2RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732342" description="Copper-containing nitrite reductase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="10">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="198"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="463" mass="49211" checksum="B8A70A3E0AE9BECB" modified="2008-01-15" version="1">MNRRSFIMVVIFSLLLASIAACSDQATRTSSLAPTASAKPESQVVSQQASQPTSQEVLEIHSFDMGFKPQNLTVPSPGVYTIKLVNDGVIPHDITFPDGTVISAKANETVTGEVTIPAEGMNFICAVPGHEAAGMKGSIQVASADAAAVTPTMMDDHSGPAPESDIAADESAPEYILHDAKAPAALEGTLHDIELVVEEKPMTVAPGYVQHVWTFGGTVPGPVIRVKVGDTVRIHLKNPSSNKVPHSIDFHSSEVAWNDEMTSINVGEDKMYEWKANYAGVWMYHCGTTPALHHIANGMYGMVIVEPKEGLPAVDHEFALVQSEWYLGPQGDLVSLEKAASAAPAPEYVVFNGVANQYKDHPLEVKTGASVRVFVLNAGPSIDSSFHVVGTIFNTVIKEGVQLRPETANGYGSQAVDLAPAQGAIVEFTTAEDGLYPIVTHAFNFVGRGALGLFQAGDGDPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y4</accession>
    <name>A9B1Y4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Alkanesulfonate monooxygenase</fullName>
            <ecNumber evidence="2 6">1.14.14.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">FMNH2-dependent aliphatic sulfonate monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssuD</name>
        <name evidence="8" type="ordered locus">Haur_2788</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the desulfonation of aliphatic sulfonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an alkanesulfonate + FMNH2 + O2 = an aldehyde + FMN + 2 H(+) + H2O + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:134249"/>
            <dbReference type="EC" id="1.14.14.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SsuD family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.5" evidence="2 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2788"/>
    <dbReference type="EnsemblBacteria" id="ABX05426">
        <property type="protein sequence ID" value="ABX05426"/>
        <property type="gene ID" value="Haur_2788"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2788"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_1_0_0"/>
    <dbReference type="OMA" id="YGFWLPI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01229">
        <property type="entry name" value="Alkanesulf_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019911">
        <property type="entry name" value="Alkanesulphonate_mOase_FMN-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03565">
        <property type="entry name" value="alk_sulf_monoox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0288">FMN</keyword>
    <keyword evidence="5 6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="41636" checksum="6E3ED9E9B13F6F21" modified="2008-01-15" version="1">MEILWFIPTHGDGRYLASTVASRSTTFPYLRQIAQAVDELGFTGALLPTGHYCEDAWVLASALSAVTRQMKFLVAIRPGLMLPGPAVRMASTFDRISNGRLLINVVAGGDSAEVASDGLHLDHDQRYALTDEFLDVWRRVLAGEHVTLEGQHIHVTDGKLMLPPLQQPHPPLYFGGSSPAALEVAAKHVDVYLTWGEPPAQVAEKITQVRALAAKHGRTIRFGMRMHVIVRETNQAAWDAANDLIRYVDDAAIANAQAAFAKMDSVGQKRMQALHNGNRNQLEVSPNLWAGVGLVRGGAGTALVGDAGTVAERMLEYNELGIDTFVLSGYPHLEEAYRVAELLFPRLPLGSKPTAPTNQTGIFGELLQLHEFSRREPAPTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B257</accession>
    <name>A9B257_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4776"/>
    <dbReference type="EnsemblBacteria" id="ABX07407">
        <property type="protein sequence ID" value="ABX07407"/>
        <property type="gene ID" value="Haur_4776"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4776"/>
    <dbReference type="eggNOG" id="COG1792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042663_1_0_0"/>
    <dbReference type="OMA" id="RDMTVLN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4834-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="31641" checksum="34DE16FE5C912E1A" modified="2008-01-15" version="1">MLSRSGNAQRATKLIVWLACFVVVLLLLDQQGILTPVTDSTARVLTPVTRTLTNIRLAISDTFGGIFGSSQAAQDLAALQERVTELENENVQLRSAAAENTTLRRTAGMRERYGWRTVIGNVVSRSADAGNRVISIDRGTVDGLAVGMPVVSHVNGSPDALIGLVDTVSQHNATVLLITDARSVVSGQVLSQVTSEQESGSISQPMGDVLGQWQLGSRLIMRHIDRDAKFSVGDDVLTAGISKALAFDAPAARIPPDVPIGRVSAIRPDGHGQQADIEPYFDPDVVRTVWIIVGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B262</accession>
    <name>A9B262_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4781"/>
    <dbReference type="REBASE" id="64009">
        <property type="entry name" value="HauORF4781P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07412">
        <property type="protein sequence ID" value="ABX07412"/>
        <property type="gene ID" value="Haur_4781"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4781"/>
    <dbReference type="eggNOG" id="COG3440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048763_0_0_0"/>
    <dbReference type="OMA" id="SHIRPWK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4839-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="149"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="28687" checksum="AAFCB37C5F628EAA" modified="2008-01-15" version="1">MIRNLWQRDELILAFNLYYQIPFGKINAKNPQVLALAQLIGRSPGAVSFKLSNFASLDPSLKQRGIAGASHGSKADLAIWNEFYNNWEALAIESEQLLAKLSPAEAAEPETNLIELPLVEGLEREQLRRVRVNQHFFRKIVLAAYDQRCCITGLNIPSLLNASHIVPWAHAAKQRVNPHNGLCLNALHDRAFDRGLITITPNYQIHVASALIKSSANSATNDLLLAYDQRQIELPTRFQPDPAFLHYHNQHIFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A5</accession>
    <name>A9B2A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1302"/>
    <dbReference type="EnsemblBacteria" id="ABX03950">
        <property type="protein sequence ID" value="ABX03950"/>
        <property type="gene ID" value="Haur_1302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1302"/>
    <dbReference type="HOGENOM" id="CLU_381196_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1324-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="310"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="669"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="726" mass="80930" checksum="3B73757962099621" modified="2008-01-15" version="1">MARTTRAIPQRTLSAEDRATFERMAESIRSLVGVHINQQPGRFMLDTRIMLDLVRFPVMRPTGGRVTWGGYFTYSPTYASLTPEQRWNYIAWLAGDESGAIQLFRIMRLYALCAELTTTRRDEAITAMRQLYDSSTNDAVAQSSIGNVLTLAYAASQPELLGEWLTLYTPSNAIPADVLIRCFALASIEASGPLLFDIASRCNFKLGRGLGGKRAAIEQAMRDIAERWGERHQTTVIRTMVEQTPTMPVALNYSDTLVMWVARALELSQGVFLFDRSDAASFIRGLAAAAQEQVRSNKKGSTPLDGLELLDGILKGDGGVVQFDLSGSAEYVMTEEEEAILEQKLARIQKVPGVKIVKNEWDVFSYWSGRQNTSPDAVLIRTLSIKQPSSPEPWNAPTPPTYAVASYKTLTPEQRWWYLDWLAGEDIKPLDVFWAVRFKGLEAAFARLSPQKAQEQTDSWFDERDPRLLKHNIVGMLETIFDQTTDESLMRAGLDLLMPLYSDFGDVERATAAFNRTPMNPDQATRLLELLWNTGGVVDGRGLLYVARVGGFNHTPLTRECFDQIAERAEQLINEWEMDNGPLSDLPIVNFSYTRSKRRVVSAVSVAADVARQAQEEIKAQRRSAPRTARMSAEEIEAEQAELAELPTNAGDGPAEAIYVQLASDPQLVELYLSYGANALDQGRPTEAVAFLRRAAELDPRSHASLLLPLARLRLSEAAHDPKPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B0</accession>
    <name>A9B2B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1307</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1307"/>
    <dbReference type="EnsemblBacteria" id="ABX03955">
        <property type="protein sequence ID" value="ABX03955"/>
        <property type="gene ID" value="Haur_1307"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1307"/>
    <dbReference type="eggNOG" id="COG2003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073529_0_2_0"/>
    <dbReference type="OMA" id="AMPDYEL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1329-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="107"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="25690" checksum="EF544027EAFA4C63" modified="2008-01-15" version="1">MSNYFISVKELPTSEQPRERLRDFGPQALSDAEILAILLRVGVQGMNVIQLAQLLLREHGGWHGLQKIEFNDLCRVRGMGEAKAAHIKAALEIGRRLLLAAPNQPLQITSPADVVGLLQVEMSHLDKEHLRVVILNTKNHVLKIENVTIGSLNSASVRIAEVFREPIRLNAAAIIVVHNHPSGDPTPSPDDILVTKQLIQAGQLLDIDVLDHLVIGQARWVSMRERRLAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H7</accession>
    <name>A9B2H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1377"/>
    <dbReference type="EnsemblBacteria" id="ABX04022">
        <property type="protein sequence ID" value="ABX04022"/>
        <property type="gene ID" value="Haur_1377"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1377"/>
    <dbReference type="HOGENOM" id="CLU_1945813_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1398-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="13170" checksum="2804EA17AED857B2" modified="2008-01-15" version="1">MPKVQVTLTDSWMYLGTTYLPGVHALDESIANVLIARGATTDAQPIEPVAAEPVQPPTPSNDGDAGTPNGEPPAEPTLESIVGSKAAATLAAAGYTTYGDAMAADDATLSAIDGIGEATIKKLREYKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B336</accession>
    <name>A9B336_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">eIF-2B alpha/beta/delta-related uncharacterized protein</fullName>
            <ecNumber evidence="3">5.3.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4869"/>
    <dbReference type="EnsemblBacteria" id="ABX07499">
        <property type="protein sequence ID" value="ABX07499"/>
        <property type="gene ID" value="Haur_4869"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4869"/>
    <dbReference type="eggNOG" id="COG0182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_2_0_0"/>
    <dbReference type="OMA" id="DMVTQSA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4929-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="39161" checksum="D618149C4BF72439" modified="2008-01-15" version="1">MTGRLPLLTRRGDTLRYDREKGIVAILNRRLYPAQTVWVDCTDLEVVAQAIETMVIQGGPPLAYAAGYGLALALDQATDYSLAQQQVVLALALERLRRTRPTADDLHTILAEAERLALQALEQNQAPNDVVYGYVAGEIQRGDRSAERCGVRAAELLTDGDTVLTVCYPGAAFNWMLYTAVVKQGKQVAVMPTETRPYGQGIRLTASQALEIGSQVTVINDNMSGFCFSRDMITVYITAADRIALDGSIANKVGTYTNAVLAKRHGVPFYVLGYDGPDLNTATGAEIPIEERNGDEVLMMNGQRIAPEGVRGYYPAFDVTPPELISSIVTDRGIYRPAMIQRYLDDSSDAPLEVIPLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B340</accession>
    <name>A9B340_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07503">
        <property type="protein sequence ID" value="ABX07503"/>
        <property type="gene ID" value="Haur_4873"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4873"/>
    <dbReference type="HOGENOM" id="CLU_1701846_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4933-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17379" checksum="021688A0A17C28E2" modified="2008-01-15" version="1">MLRKSIITIVGGSILICVLLMVFEPVQAYATLGPIDDFPIYLDSSNVRHNGQAMHYVVLRKLEPHELEDFYIAALAKRDWHMQPTTINQPPASLRFRHASITGIVELTISHHHGGYQPDWSEVDARYVDAQLRPVTAPPLNIRWHVNRFGCGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3H0</accession>
    <name>A9B3H0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1489</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1489"/>
    <dbReference type="EnsemblBacteria" id="ABX04133">
        <property type="protein sequence ID" value="ABX04133"/>
        <property type="gene ID" value="Haur_1489"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1489"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_0"/>
    <dbReference type="OMA" id="HERYRMQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1511-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="180"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="240"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="465" mass="50440" checksum="35DAB506FA87EDF0" modified="2008-01-15" version="1">MRRIWQLRHSLATKLILAFLLVGLIGISLVALLVVVRTRSEFSRFLSERDRTALANALAEHYAATGSWQGLSQALDAQPGLIELRQNVVLVDANGAIINSLQESTATQTMQDILRFAGEPIVVNQQTVGYMLPHPMTVPNPELPPPSPEQDFLARVTWAATASASAAILLALLIGALLAQTLTRPIRALITATHKLADGTFDHRVTVQSHDEVGQLAQSFNQMSAKLARASQQRQQMTADLAHDIRTPLSILRSYTEGLKDQRFVGSPTIYNVLHEEVEHLQRLVEDLRVLSLADAGELVLNRRMIDPRAILERVGLAHIMQAEAQGIALTVEASEQLPSIDVDTDRMTQVLNNLVSNALRYASAGAISLGAQLRGDQVVITVQDTGSGIDAADLPFIFDRLYRADKARQRNASSTSGLGLAIAKAIVEAHAGTISVDSWVGSGTTFTISLPVANPHAQIRPKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L2</accession>
    <name>A9B3L2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2946"/>
    <dbReference type="EnsemblBacteria" id="ABX05584">
        <property type="protein sequence ID" value="ABX05584"/>
        <property type="gene ID" value="Haur_2946"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2946"/>
    <dbReference type="HOGENOM" id="CLU_2355867_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2978-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735235" evidence="1">
        <location>
            <begin position="29"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="10548" checksum="D3FAADE59CDE3194" modified="2008-01-15" version="1">MRALVVSSLSICFTMLLVVALLTAQSLAGVEQAQAQTIGAQQAAQTFQHHIQQTAVNIAFYRLIDHGASRIQSAASIKPIYIPEHILGRYQLTMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B452</accession>
    <name>A9B452_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tail Collar domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4955"/>
    <dbReference type="EnsemblBacteria" id="ABX07585">
        <property type="protein sequence ID" value="ABX07585"/>
        <property type="gene ID" value="Haur_4955"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4955"/>
    <dbReference type="eggNOG" id="COG4675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087872_0_0_0"/>
    <dbReference type="OMA" id="NFQPYLC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5018-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="18124" checksum="21C852F2034DB785" modified="2008-01-15" version="1">MAQPYVGEIRMFGGNFPPAGWMFCEGQLLPISEYETLFQLIGTTYGGDGQETFALPDLRGRFPLHQGNGFILAETGGAETITLTVQQMPAHSHPALVSANNGTTNIPQNGFWAKAGATNLYVAGASAGDLSPFANNTISLIGGSQPHENMQPYLVVDFIISLYGIFPSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B5</accession>
    <name>A9B4B5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="4" type="ordered locus">Haur_0020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0020"/>
    <dbReference type="EnsemblBacteria" id="ABX02672">
        <property type="protein sequence ID" value="ABX02672"/>
        <property type="gene ID" value="Haur_0020"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0020"/>
    <dbReference type="eggNOG" id="COG1722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145918_3_2_0"/>
    <dbReference type="OMA" id="VRYCQQK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006488">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="68" mass="7652" checksum="BE355E98420430F7" modified="2008-01-15" version="1">MSNNLSYETVFHELEQTVHALEAGDLPLEQALSHYERGMVLAAQCNQLLQNAELRVQQIINGQLISTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H5</accession>
    <name>A9B4H5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1496"/>
    <dbReference type="EnsemblBacteria" id="ABX04140">
        <property type="protein sequence ID" value="ABX04140"/>
        <property type="gene ID" value="Haur_1496"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1496"/>
    <dbReference type="HOGENOM" id="CLU_1088918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1518-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="240" mass="27625" checksum="C5BF780CCC41DD96" modified="2008-01-15" version="1">MDKQQIIEQISLELYTLESEDAHWFGSEANNPNQLWYSSDLAHTIDDLIWDESNGLTNLQKVQLLFSIYEDLPCYTLLSLNWSRYQQFDGATQELYWSEVRRILLQGKLAWSGPLEYHLTTDWFELCDNCQDIWNRLTHNPNSALLASILNSSATAAWYLKAPIYAQLIADPHWHPAIYQSLYASYYALYGQIDKHEALVLLQGLVVDESRQTELATLIRKLQTGDRYTNSAGVKGLQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B585</accession>
    <name>A9B585_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3586"/>
    <dbReference type="EnsemblBacteria" id="ABX06222">
        <property type="protein sequence ID" value="ABX06222"/>
        <property type="gene ID" value="Haur_3586"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3586"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_0_1_0"/>
    <dbReference type="OMA" id="GWILWYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3625-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="4">
        <location>
            <begin position="70"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1123" mass="124585" checksum="F7D24D512E05ED44" modified="2008-01-15" version="1">MTVQTTTCCSTCNFAENPPSARFCGNCASPLPLHCFSCGAANPPGFRFCGTCATGLIEYIPAATTRRVVTILFADVCNYTNLTNRLGAEHMYSLLDPCLRRLGETVRRFEGTIDKFTGDGLMAVFGMPVALEAHAAQAAYAALAMFEELAAYNETIAHAGVQFQIRVGLASGEVIAGLLGSDRYSDLTVIGGPVNLAARLQQVTDPGTIMVDGDLAQSLQTSFMFNEQHPVALKGFEQPITAAILAGKQLAQAVVDGSFGLPLIGREAELRNLIGATELLHNGMGGVIGLTGRAGVGKTRLTAEIIQHLHSREVKVLTNDCSSATRIVPYSAFLGLIRQLFQIDHADSAATIHHKIQLMIHSLGNMPLDLLPYIEYLLSLDFIDQSLVERVQHLDAAQLKRHVFLAIRELLVACTRQQSMAIVIDDVQWADDLSLELLEFIAETFDASSLLLYLVARDDETPQIRQTFNRILAQARQRGLVLELNSLSPEAAEALIKQILPQASAVMIDHLVRQADGVPFYLEELARHALHAGLDIQAQSSDSLQIPSMPLSLQALMRSRYDRLPNDLAHSLALAAVIGRRFSQQLLCQLRPEQPINQQLQQLQQRGFVQPIANHHDDWAFSHLLLQETIYASLLQQQRYNLHGEVALALETHDEQRPELYLDALAYHFSRSQLTHKALEYLLLAAQRAASRFANDDALRLYDQAMPLLSELDHPAAEQAVSLFHGRGDVLSFVGRYDEARMAYQQAMSMIQPNPETQATHATILRQLAATYEKQGNYDEAMLHLDQARLVLADGALFDHARIDCDAGWIAFHRGNLTQAERLLNNALTISELNQHHGLQALAANRLAGVYWQRGSLKAAQALVNQSLAVSRYLGDLPAMSRALNNLGVIAMELVDWHAAANYYEQSLETTQAIGDLNGQILAINNRSHCMLMLGLLNDALRFSQMAFRLARQIGAKLHMATALIQQGTISFYVQDYPRARRYYLQAEQLFRELGHYDPKRVILAEMLGRIAFVEGRRACANRMAARALRLAQQLNEPQSLFRSQALQIYLQAYNGQRRQASEAIDQLLQLSVNNNYLLALGLIIGATIKRLNGDYTVALAHQERADILFEQMNTPAMLREYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A6</accession>
    <name>A9B5A6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0079"/>
    <dbReference type="EnsemblBacteria" id="ABX02731">
        <property type="protein sequence ID" value="ABX02731"/>
        <property type="gene ID" value="Haur_0079"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0079"/>
    <dbReference type="eggNOG" id="ENOG5033QS7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_437977_0_0_0"/>
    <dbReference type="OMA" id="WENIRAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-80-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="634" mass="71511" checksum="0E3F60FA1F91A16A" modified="2008-01-15" version="1">MAFATPEQVHRYPRRFKWIFEVLCTVLIVVAVVRWGRAVLQYLWDSRNINAAFAARDTFYEPLVNWFNQTGTTRPRLRDLADLAPYFGWLGLTLLVVVFVRNFFPTIRTSSRGILIEWGNGWLPVGWEQVSGLRVTEDLSGERFVVLLQTNNKALTGWHRFYSVLYRFSLRRGILITSGISDFLPLVRMLTSELEQVARQTKQPAVKLDEKASSPLFQLLLSPAGFFSRRSKSDKDYVEYATQAGLTAQPGRVASIMATYPKRISSLLVIGTAVMAVLGLLRVLEMLRQWIGLSFGVGGIFKSAPLPLDQSAWWLPVAAVLLLVVLIPILVVIRNILPDIESRQEGLMVRYFNRWLLVRWEEIIAVKTASLSENNHVMLIQTTNQSLKMMHHISSLLFDGSNARGVLLTSALSVYDPLVQQIVLEVSRRQRPSEQDEGILTEDAPAWLLRLMFKPSDAIDRMVSNILRREDSTKIKFDTMMILGRPMVWLTAIPTLMLLVERHINGVHYPTVSSIINVLVFVFICLLEYPIAAAVAQFSERNLDGDAHLARPFYLYPTAQLPRIVVMLGALLLLVLNVPLLPVLLWIGAAIWSFLLTAGLWEGLYGWSGGKLLGIGAIPAIIQVLALMMWASMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J2</accession>
    <name>A9B5J2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0165"/>
    <dbReference type="EnsemblBacteria" id="ABX02817">
        <property type="protein sequence ID" value="ABX02817"/>
        <property type="gene ID" value="Haur_0165"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0165"/>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054549_1_1_0"/>
    <dbReference type="OMA" id="RYNQSAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-168-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="120"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="24191" checksum="5BF999977FAAF61F" modified="2008-01-15" version="1">MINRLWNSLLDLVYPPRCYSCGKAGTQFCPACFAECIPLTPPQRPQPLAANSPLERALGIYPFQGSLRAAIHAFKYQNAHPLAQILAPLLFDFCAWNDVVLMPVPLHGVRKRERGYNQAELLARHLAKAWQLPLSTDLQRVRATEHQVGQQAQARASNVAGAFAWRGQQPAPNHVLLIDDVLTTGSTFEACASALIAAGSTAVEGLALAKAVIKPAPPLDSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J4</accession>
    <name>A9B5J4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0167"/>
    <dbReference type="EnsemblBacteria" id="ABX02819">
        <property type="protein sequence ID" value="ABX02819"/>
        <property type="gene ID" value="Haur_0167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0167"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098254_0_0_0"/>
    <dbReference type="OMA" id="RVWLHTC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-170-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="20897" checksum="1C6FBDFB7321DEDF" modified="2008-01-15" version="1">MQREVTTTYLEMLAISELKPSSRDEPAFGFAQVQRISPELNRFLYTAVGGQWYWLDRLGWSYQQWLDYLRQPTIQTWLGTYQGIPIGYCELVQEADGSAQIGYFGLLPQWYGQGLGGLLLTKVIQQAWQLTSSRVWLHTCTLDGPTALANYQARGFKLYDQKTEVVELPSQAAGPWLGAYSNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z6</accession>
    <name>A9B5Z6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3152"/>
    <dbReference type="EnsemblBacteria" id="ABX05789">
        <property type="protein sequence ID" value="ABX05789"/>
        <property type="gene ID" value="Haur_3152"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3152"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_5_2_0"/>
    <dbReference type="OMA" id="QRISRRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3184-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="15225" checksum="EAABFEE91F9579DC" modified="2008-01-15" version="1">MQQLSISMVAKQAGIKASTIRYYEEINLLPPAARQNGRRYYDQQIFERLAFIRTTQRLGFSLNEIQLLFQHEQQQAPLAGLWRQLAKQKLADLSQLLEQASHVQQLLQRGLRCRCATLEMCVHCVLQHCQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B684</accession>
    <name>A9B684_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multiple sugar-binding periplasmic receptor ChvE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3659"/>
    <dbReference type="EnsemblBacteria" id="ABX06295">
        <property type="protein sequence ID" value="ABX06295"/>
        <property type="gene ID" value="Haur_3659"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3659"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_1_0"/>
    <dbReference type="OMA" id="SARWIDD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3698-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735488" evidence="1">
        <location>
            <begin position="24"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="54"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="40722" checksum="929898FC83064B59" modified="2008-01-15" version="1">MTMKSPRAKFMMVLMLLMTMVLASCGEAATPTTAPTDGGTGGTTASSDNSKFTIGISMPTKSSARWIADGDNMVKYFQEKGFKTDLQYAEDDIPTQLSQIENMVTKGVNVLVIAAIDGETLSDVLQSAKDKKILVIAYDRLIKKTPNVDYYATFDNFQVGVLQAQSIETKLGLKEGKGPFNIELFGGSSDDNNAFFFYNGAMSVLQPYIDSGKLVVGSGQTGMDKVATLRWDGATAQSRMDNILSAFYGDKRVDAVLSPYDGISIGIISSLKGVGYGSADKPMPVVSGQDAEVPSVKSIIAGEQSSTIFKDTRELAKSVVGMVEASLSGKEVAVNDTKTYDNGVKVVPSQLLVPVVVDVTNWEKVLIDSGYYKKEDITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6A0</accession>
    <name>A9B6A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3675"/>
    <dbReference type="EnsemblBacteria" id="ABX06311">
        <property type="protein sequence ID" value="ABX06311"/>
        <property type="gene ID" value="Haur_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3675"/>
    <dbReference type="HOGENOM" id="CLU_1515909_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3714-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="18957" checksum="62DDD9980D3B2CDA" modified="2008-01-15" version="1">MTLDQWFYLAALGFGGAIIAITKIRRQPLWPSLERMQRSSRWLIFQPLVLASWLIMAAGVGFLARGAGVNWWLSGMIALAGGLAVGLLLYRMIIERSIVQQAGTAQSKVGPIGQLGVVVEALPVDGFGVVAYEHQKGAARINARAIGGRAIEAGCAVMIVEVNEQGATVLRLESLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G0</accession>
    <name>A9B6G0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NurA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0211"/>
    <dbReference type="EnsemblBacteria" id="ABX02863">
        <property type="protein sequence ID" value="ABX02863"/>
        <property type="gene ID" value="Haur_0211"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0211"/>
    <dbReference type="eggNOG" id="COG1630">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059379_0_0_0"/>
    <dbReference type="OMA" id="HEIAYCY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-214-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018977">
        <property type="entry name" value="NurA_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09376">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00933">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NurA" evidence="1">
        <location>
            <begin position="82"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="44499" checksum="A094C1DA490A81DB" modified="2008-01-15" version="1">MPLDFNQVGQQIKQMGGDLRQTANHHDQLVAHAWAKLEEQSPRWEHWARHAEENYLRSPWLLAAPAEPIINRYQLPKFPPNYCLAAVDGSQIDLDRHWAVECYLINLGLVTIQYGQQPYSKLHSVPALHYNDQELLLRDKDGRSYKMAGALVHAERDTREGIALARLAQEILEQSTTPLVAMQDGTLIRWSLSGLDPWVRAHFLQRYLDEGLAALRAADVPTCSYISHPKAPEVTGIARLIVNPTLNNTNKAEGLVDPYPGINDTKLFGNGWLGDGERSALFKSLSKINVEEYRDHAIYFFYLNVGSELARIEMPEWVAQRPEWVDLIHAVAYDQAHRGGGYPVALARAHEQAVVRESDRRVFRQMIEQALWHARLNNGSSLKQDAKAQVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K1</accession>
    <name>A9B6K1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0252"/>
    <dbReference type="EnsemblBacteria" id="ABX02904">
        <property type="protein sequence ID" value="ABX02904"/>
        <property type="gene ID" value="Haur_0252"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0252"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054927_3_1_0"/>
    <dbReference type="OMA" id="NFFIDMS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-255-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="44"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="33217" checksum="9BE68EF1287549F1" modified="2008-01-15" version="1">MSEQAALFEPQFLKQLDRLALLTRRNIAGQMQGERRSPRRGSSVEYADFKPYTPGDDFRQIDWNLYARLEKFFLKLFVAEEEITLHLLIDTSASMDWGEPNKLRYAAQAAGALGYIALASLDRAQVTSFGGGNEQRIPAGRGRAGVPPLFNLLNRLKGNGNTSLLQASRRYIQTARVAGPLLLCSDLLTPDWEEALRTLGRRPFEITVLHVLSPDELNPPFEGDLKLLDVEGGESLDVSADLDLLQRYVERLQAWREEVEHFCTTRGINYIFVDTSLPLESLLVSVLRERQIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L0</accession>
    <name>A9B6L0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter, periplasmic binding protein, thiB subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0261"/>
    <dbReference type="EnsemblBacteria" id="ABX02913">
        <property type="protein sequence ID" value="ABX02913"/>
        <property type="gene ID" value="Haur_0261"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0261"/>
    <dbReference type="eggNOG" id="COG4143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_6_1_0"/>
    <dbReference type="OMA" id="PTTNWMY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-264-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13545">
        <property type="entry name" value="PBP2_TbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005948">
        <property type="entry name" value="ThiB-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01254">
        <property type="entry name" value="sfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731935" evidence="2">
        <location>
            <begin position="23"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="41165" checksum="84B5387B5829BDC6" modified="2008-01-15" version="1">MKRWLLSFLTIGSLVLTGCGAAATPTAETAIQPTPATTAAADVTPAATQATQAPTDSGQFAGQTLVVVSHDSFAISSEVISGFEQMTGATVQILESGDAGEALNKSILAKGAPLGDVLYGVDNTFLSRALDADIFEAYAAKNLEQIPAELKLDSQNRVSPVDVGYVTINYDKAALAEAGLSLPTDLRDLTKPEWKGKLVVENPATSSPGLSFMLATIAHFGESSDYTWRNFWSDLRANEIKVASGWEEAYYGDFSGASDGQYPLVVSYATSPAAEVIFATTPLTDAPTGNLLLPGGAFQQIEFVGLLKDAKNPELGKAWIDYMLSDTFQSDIGGQMFVYPALPSAKVPAEFTQYAQVPSNVTTLAPAEIAANRERWLNEWQETVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q1</accession>
    <name>A9B6Q1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1717"/>
    <dbReference type="EnsemblBacteria" id="ABX04360">
        <property type="protein sequence ID" value="ABX04360"/>
        <property type="gene ID" value="Haur_1717"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1717"/>
    <dbReference type="eggNOG" id="COG5632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631303_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1744-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="434" mass="47930" checksum="44EBE37FCA4E3ACD" modified="2008-01-15" version="1">MTDANQPLHDEPLPEFDLPDPKDAMPHEDTLSEEGTRGVVPVDQFLYVGQGLKADEFTHYVDTYNFGAVPPNFVVLHHTAVPSTAAAPYPSGWRWDNQETGLSEGQIYRKRLKQLETLREYYRTSAGWDRGPHLFIDETWIWLFTPMYDQGIHAAQGNGYRDSKGTLQYSIGIEVCGYFEKTQWSAPVAALVGHAVAVLKRKLNSFEIRYQKFGGGISSHRDYNKPSCPGAAITESYYISTIQNAFDRLSNVQSTPIADNPITTNTPLLSATPSGSREKAIAFIRKSLPDNSEYKNDIETIMGYYWVYAPSVGLDPFLAASQCIFETAGLTSGWAARPKRNPAGLGVRQEGGLSFSTWDGAVQAHIGQLLALALRDDEANQAQKTMMAANPRHGNIPANLRGVAKTLAGLSNNWTDDADYANKFATRAEAIRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S3</accession>
    <name>A9B6S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1739"/>
    <dbReference type="EnsemblBacteria" id="ABX04382">
        <property type="protein sequence ID" value="ABX04382"/>
        <property type="gene ID" value="Haur_1739"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1739"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_10_1_0"/>
    <dbReference type="OMA" id="GIWMFGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1766-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731939" evidence="2">
        <location>
            <begin position="22"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="3">
        <location>
            <begin position="84"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="352" mass="37286" checksum="8CDEDCDE0B14307A" modified="2008-01-15" version="1">MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPADSAAGTRTIKHVLGETTITGTPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPVELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYPQYSAIAPTLVFNPYPESGDQYAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNAAEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDNPFASGTVKPFWDSLEFVKKGQAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T3</accession>
    <name>A9B6T3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">APS reductase</shortName>
            <ecNumber evidence="3">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysH</name>
        <name evidence="5" type="ordered locus">Haur_1749</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1749"/>
    <dbReference type="EnsemblBacteria" id="ABX04392">
        <property type="protein sequence ID" value="ABX04392"/>
        <property type="gene ID" value="Haur_1749"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1749"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044089_2_0_0"/>
    <dbReference type="OMA" id="PIARWTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1776-MON"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="41"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="26146" checksum="59C0F5C419A8557D" modified="2008-01-15" version="1">MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALKLEPNLPVLVLDTGLLFSETYALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPDLCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVSWNEKHQLVKICPLALWTERDIWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U0</accession>
    <name>A9B6U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1756"/>
    <dbReference type="EnsemblBacteria" id="ABX04399">
        <property type="protein sequence ID" value="ABX04399"/>
        <property type="gene ID" value="Haur_1756"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1756"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1784-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="119"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="21366" checksum="DB7D2566CB7EEBBE" modified="2008-01-15" version="1">MIRIQQPTLDSPTNQIDFAELYTQQYASIYRYIAYRVRDPASTDDLVAHTFERAMTRIETYRAERGSPGAWIFGIARHCVDSYFQRQRRQRWLSLDFIREHVADNTDPIADTLRSETNQQLYQALKKLKAHERDVIALKFGAGLNNRQIAEITGHSESNVGVMLYRSLQRLRQWLPNRGYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B721</accession>
    <name>A9B721_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3252"/>
    <dbReference type="EnsemblBacteria" id="ABX05889">
        <property type="protein sequence ID" value="ABX05889"/>
        <property type="gene ID" value="Haur_3252"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3252"/>
    <dbReference type="HOGENOM" id="CLU_1029633_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3287-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="29437" checksum="62DC2F4B1E8AFC2D" modified="2008-01-15" version="1">MQAIRELTYPVRLSSAGLFALLSLVSAPTLLGAGVKSPYTLDEAQATALWEQGSNELRKHGWLIDDPTTHTSVINEDLLLLIISAVNAELVVLSTWQNDSGRKYDVAYYEHGHTVVEMQMLGSLYEFTVLSNRNVALQCFASHFEPAFPQAIKQPIQFQLTQEQALAAKQNPDVQLLHTFGVSEIAAHQFAATLQKPRLYGTIDILRTEATKVIESRIVGIILADTTAWIGFVTPDGLTDYHNVGEADFINLLDQAMSDLNEINVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B748</accession>
    <name>A9B748_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06331">
        <property type="protein sequence ID" value="ABX06331"/>
        <property type="gene ID" value="Haur_3695"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3695"/>
    <dbReference type="HOGENOM" id="CLU_1347378_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3737-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="23068" checksum="3DBD4DD554A894BC" modified="2008-01-15" version="1">MIINVELALLVSGGIVLEVPLPPPQAAWNFDALLDYHGDGRFLCWWWHTQYNHLIALANDGWLRAEAGLWHMNFVQDLRDACLLNPQLAFGNVFGEQPTHALLYDREQHCLLAVTLTAVLELLDHSIHELEPQQINYREIKRVLLALTTKPDLLSYAVNQLHIYEAKTGAGAFNLLCEPCNDWRMCQFSAWLNAAIRNQIGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B760</accession>
    <name>A9B760_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polymorphic outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3707"/>
    <dbReference type="EnsemblBacteria" id="ABX06343">
        <property type="protein sequence ID" value="ABX06343"/>
        <property type="gene ID" value="Haur_3707"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3707"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021408_1_0_0"/>
    <dbReference type="OMA" id="GALYMDC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3749-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003368">
        <property type="entry name" value="POMP_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01376">
        <property type="entry name" value="POMP_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="518" mass="54472" checksum="1C52C9E680255CA8" modified="2008-01-15" version="1">MVFLIGRMLLVLGLLAGVWPKPSQASAILIDCNTTAVSAAISAGGAININCNSPTVLTFGSELVMNQATEINGNNNAIFDGQNTRRLLRSANNLKITLRNLTIRNGRTTDQGAGIKVGFWNTLSISNVRFENNQATKDTAACDGGGAIFIGGGSSAMIDHSTFINNRANNGGAINSLRTNLMVSNSSFEQNSAMHTAAINQHGDCGGGGAIYIDGTRMPNDGGPDGIVLLNNSYTSNTSNNHGGAIFIGLYSNETATIERSSFTNNSVTYATSADWSGTGGAIWYGFAAGGVTNERLFINNSTLEGNKAIGQGGGLWVDAPATIRNTTFYANDATDPRSYPDDQEWRKGNGGALAVNNNAAVDITNATFMNNHAGFNGGAIAGQTITIRNTLFYNNTTDWSIKIMQHCTNALIDGGNNLQYPPKNPNPNYWNETNCTSSMRTPELTLSNIANNGGSTRTAALPAGSPAINLGNPASCSALDQRGYTRAGACDVGAYEYNGAAFSPSHSIYIPLARKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B779</accession>
    <name>A9B779_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MBOAT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3726"/>
    <dbReference type="EnsemblBacteria" id="ABX06362">
        <property type="protein sequence ID" value="ABX06362"/>
        <property type="gene ID" value="Haur_3726"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3726"/>
    <dbReference type="eggNOG" id="ENOG502ZT7B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_885015_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3768-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="MBOAT_2" evidence="2">
        <location>
            <begin position="182"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="36344" checksum="E126BD7522C760E3" modified="2008-01-15" version="1">MRVLWLIGVLSSTGLALLSLPQLLRDAQQRRWAAWFLALFAIGNGLWLSQPWQIWGRIFATWIPSYLAFKGWRLLYSPHAQIKQLGFWRSLGFILWLGMELEPWELPRQPDLAWRKNLLIGALWLGLGLAIGLLAWWLPAPNTDLWLLWRCWLALVGLVIGLFFGVTRLYLALWQAFGWQVQPLFLQPIYARSVSEWWGKRWNLAVHTVLSLVFWQPLKPIIGWRWAAAVVFIASGLLHELLLSYPAAGGWGWPLGYFVVQIGATSLERLRSVRAWLRQSDRRQASWTLSWIIIPAPLLFRPELILGLFAEHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B788</accession>
    <name>A9B788_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3735"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06371">
        <property type="protein sequence ID" value="ABX06371"/>
        <property type="gene ID" value="Haur_3735"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3735"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_0"/>
    <dbReference type="OMA" id="GMQNHTA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3777-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="37"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="173"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="39770" checksum="FA48F18F1B414A82" modified="2008-01-15" version="1">MQQLRIAFLDSWLQAVVDGSGTAAAIGGLARTLQARGHVVDRIVPTGNWPRNLTLRRLYYNWQLPRRLANHRYDLVVGFDIDGFRVAQRLNVPYICSIKGVIAEEQRHEQGFIRALLWSLSRIELINARRAPKVISTSEYCRQMIHAHYAVTISKIGIVPEGIDLSLWQEQAHSSQRDPWTVLCVARQYPRKHVIDLIRAFASVIEQVPQAQLVIIGDGPDHDMLRGVVRAYNLESSVRMLGAIADDAEVRAWYGRSSIFCLPSVQEGFGIVFLEAMASGLPIVSTNAAAIPEVVPHGQAGTLVEPSDVTAIAEALIELLQNPELQQRYRDYGLQHVQQYAWEHVTDRFLAAVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D9</accession>
    <name>A9B7D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate dehydrogenase and fumarate reductase iron-sulfur protein</fullName>
            <ecNumber evidence="8">1.3.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3786"/>
    <dbReference type="EnsemblBacteria" id="ABX06422">
        <property type="protein sequence ID" value="ABX06422"/>
        <property type="gene ID" value="Haur_3786"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3786"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_0_0"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3828-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27538" checksum="434FF3E4966EAE5B" modified="2008-01-15" version="1">MKVTFRVPRFDAATDFTAKYQVYHVEVNQFTTILDALNIIKDEQDSSLTFRRGSQSGIDGSCGMMINGRNRLASTTRVLSLNSTEIAVGPLPGFPVIRDLVVDFDSFFAKDAVMLPYLVTDIAKPADGKERLQSPKDANRIALAASCNQCGCCTSACPVHWSNGEYYGPSALTRAYRFVEDSRDTAIKARLDIVGSETGVWRCHTVFNCSECPKSIPNGENIQALKRKIMLNKIGLGRIEVKVARTEATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F2</accession>
    <name>A9B7F2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0273"/>
    <dbReference type="EnsemblBacteria" id="ABX02925">
        <property type="protein sequence ID" value="ABX02925"/>
        <property type="gene ID" value="Haur_0273"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0273"/>
    <dbReference type="eggNOG" id="COG1814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038957_3_0_0"/>
    <dbReference type="OMA" id="SRIGWLR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-276-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="23573" checksum="9C0907F3FCC425EA" modified="2008-01-15" version="1">MVTSHREQHRTQHIGWLRASVLGANDGIVSTASLVVGMAASNASHQSVVVAGIAGLVAGAMSMAAGEYVSVSSQADTERADIDRERMELAVDAHAERAELAAIYGRRGLDASLAEQVAEQLMLKDALAAHARDELGISETMSARPIQAALASAAAFAVGAILPLMTAVLAANSYLVVLVTGTSLIFLTLLGILAAYTGGSSIIVGAMRVAFWGALAMALTAGVGAIFGTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I2</accession>
    <name>A9B7I2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX02955">
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        <property type="gene ID" value="Haur_0303"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0303"/>
    <dbReference type="eggNOG" id="COG3526">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-306-MON"/>
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        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
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        <property type="match status" value="1"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="62" mass="6793" checksum="F70422FD9AD81D47" modified="2008-01-15" version="1">MAAQLLEIHRQAIQQLSLIPAKGGCFEVEVNGQLLYSKLQTERHAEAGEVEGLIAAYLDQQA</sequence>
</entry>
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    <accession>A9B7I8</accession>
    <name>A9B7I8_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    </organism>
    <reference evidence="2" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX02961">
        <property type="protein sequence ID" value="ABX02961"/>
        <property type="gene ID" value="Haur_0309"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0309"/>
    <dbReference type="eggNOG" id="COG2315">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_105851_1_1_0"/>
    <dbReference type="OMA" id="NKRHWNT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-312-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
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    <dbReference type="InterPro" id="IPR007351">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR35145">
        <property type="entry name" value="PTHR35145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="13293" checksum="B5621971E0EB4DEC" modified="2008-01-15" version="1">MSNHVDYAQARSYCLSLDDVIEDYPFGIEPLVFKIGDERGKMFALLVRSEPAQISLKCDPDRAEMLREQYPAITAGYHLNKRHWNTIVLDGSVPDEECLALIAHSYDLVRPKRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L5</accession>
    <name>A9B7L5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase membrane zinc metallopeptidase putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0336</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0336"/>
    <dbReference type="EnsemblBacteria" id="ABX02988">
        <property type="protein sequence ID" value="ABX02988"/>
        <property type="gene ID" value="Haur_0336"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0336"/>
    <dbReference type="eggNOG" id="COG2738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084406_0_0_0"/>
    <dbReference type="OMA" id="VQHATAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-339-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007395">
        <property type="entry name" value="Zn_peptidase_2"/>
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        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="25386" checksum="96BB4959AF485396" modified="2008-01-15" version="1">MIFDPLYFVFAIPGMLFAFWAQWYVKSTFSKYANVANMHNMNGFAVAQRLMNAEGLNYVRVNQVAGQLTDFYNPADKSINISQSSVNPSVAAMAVVAHELGHALQDREGYAMLRLRSSIVGIANIGSNIGTWLVMLGLMFGAASRSGGIGFTMALIGLVLFAGAVLFTLVTLPVEFNASSRAKKMLIANGLVSPQDQAAVSKVLNAAAWTYVASAAQSILTFAYFAFRVFGGRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q1</accession>
    <name>A9B7Q1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1786</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1786"/>
    <dbReference type="EnsemblBacteria" id="ABX04429">
        <property type="protein sequence ID" value="ABX04429"/>
        <property type="gene ID" value="Haur_1786"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1786"/>
    <dbReference type="eggNOG" id="ENOG50332T0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1675507_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1814-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17568" checksum="96C3F27CE439DE3A" modified="2008-01-15" version="1">MFRSEHLHIAGRLTIQQFTSAGELVEQISAHNDITVAGRTLVARLFNHEKQGDVIQRVSTIQLGGSKAAFNPSHTALVQPIGTTKIARIEQLDVTDSSNKPRIMLRLTGELGERDCNGELREAGLFTEDGVMYNRVIFDTITKSEQFKLTLIWEITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7V7</accession>
    <name>A9B7V7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1842"/>
    <dbReference type="EnsemblBacteria" id="ABX04485">
        <property type="protein sequence ID" value="ABX04485"/>
        <property type="gene ID" value="Haur_1842"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1842"/>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075524_0_0_0"/>
    <dbReference type="OMA" id="VWTVPYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1871-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29329" checksum="A705F956F35ADF63" modified="2008-01-15" version="1">MKQYIPTHDIVLITLDTLRYDVAVAEWTNGGTPNLRALLPHGWQERHSPGSFTYAAHQAMFAGFMPTPATPGPHGRLFAARFAGSETTTEQTFTFDAPEIVTGLAQVGYRTICIGGVGFFNRQTALSCVLPDLFHESYWEPRLGVTEPRSTEFQVALAVERLQAIPAEQRIFLFINISALHQPNCHYLAGATGDSLASHAAALRYVDRQLPALFAALRQRNPSFLMICSDHGTAYGEDGFSGHRLAHPTVWTVPYADCSLEEAHASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7W1</accession>
    <name>A9B7W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1846"/>
    <dbReference type="EnsemblBacteria" id="ABX04489">
        <property type="protein sequence ID" value="ABX04489"/>
        <property type="gene ID" value="Haur_1846"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1846"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054192_0_0_0"/>
    <dbReference type="OMA" id="DDDWRYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1875-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="34882" checksum="932AF22E15C29D6B" modified="2008-01-15" version="1">MVFDWIGYFGDSTIANWDGQEQFESIGHPVRLHLEYDYEAKSAPQPWAEYFNAWLATDEPAQTTGLVIGRWWHEQVDPGNIDAVLASISAAREQLPLLKALFVGDFTYEEWEISWITQGNYAPVLAAFPQLEYLVIRGGSELSFGAVQHQQLKALIIQTGGLAAQVVRDVVAADFPALEHLELWLGCDFYGGDSTLADLQPILKAECFPNLAVLGLRDCEYADDLAQALVDAPILEQISYLDLSLGNLSDVGAEVLFASEAIRSLDFLDLHHHYMSNELLDCWATIGLNVDVSEQQIPQEHEGEQHRYAAVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z7</accession>
    <name>A9B7Z7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multi-sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3293</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3293"/>
    <dbReference type="EnsemblBacteria" id="ABX05930">
        <property type="protein sequence ID" value="ABX05930"/>
        <property type="gene ID" value="Haur_3293"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3293"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_51_0"/>
    <dbReference type="OMA" id="IRANCEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3330-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="327"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="570"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="692" mass="76198" checksum="6B6DF1821555FB10" modified="2008-01-15" version="1">MDPHHASEQPTVAQHASLARHEYAAEAVQPQSDRGGLLEQTQTILGQNLPLDMLYRQIVTAIARSFANSLISIYAAHTDILQLQCQHGFGHNPEQLSFQQGIVGRCARTKQAYLIAYVDQDPDFIRSHPHIQSSICIPLLAEQQLLGVLMVESIVDTLNQADAEILANVCQQLSNAIAQAALWRPNSLIDQHYRAMLDAMPDGIVVQQAGRIVYINAIGIELLGFENRHQLLGSDLAGLLEQTSNTIQKLFDQAITTNQALSHELQYDTTKTPEIPLRLTIIPITFAGNTAVQIVIRDHTAIQQREAAQQLANEREKRKSLGLLAGGIAHDFNNILMGIRGNVSLGLLDLIPTHPIYHQLQEIEKLAIRATELTQQIVAYTGGSLFVSSTVDLNEQLRELTTTFSEQAHPTTSITYELDDQLGLLKGDVNQIRQMILSIFKNSVEAIEHRYGAIQITSKLQTYTQAPHTATGLPKLAPGSYLTLSIRDNGVGMDARTQRLMFDPYFSTKFTGRGLGLAAVLGMVRAHHGSIAVWSQPQMGTEVTVLLPPHSILQPTPAAPNEDVHSVHNVVMLIDDEPAVRMVTERMLQRLGLTVQGFSDGESAIKVFREHAHEYQLVLLDLTMPQFNGIDTAHGLRAIRADVPIVLMSGYSVDSMLDPLLNDGLAGFLQKPFTLGDLQRTVNSVSALKARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B823</accession>
    <name>A9B823_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3320"/>
    <dbReference type="EnsemblBacteria" id="ABX05956">
        <property type="protein sequence ID" value="ABX05956"/>
        <property type="gene ID" value="Haur_3320"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3320"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018297_3_1_0"/>
    <dbReference type="OMA" id="QVICVTH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3357-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="6">
        <location>
            <begin position="6"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="309"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="64306" checksum="246B81E4E5CA866C" modified="2008-01-15" version="1">MLLELFIADFAIIDQVRLHFTPAFNVLTGETGAGKSIMIDALGMLRGERSDPSFVRAGSNQARVEGIFTLADRPDILPILAEYGLDGADDDQIILTREIHGASGRSVARINGRAVSSAVLRDIGGRLVDIHGQNDSQTLFNVRTHAEMLDRYAGVVADREQLSQQVIAIEAVRSQISTLRNAEARRLERIEELTFLVEELTNAKLIAGEEATLTNERGLLQNSAKITGTVDTIYRLLRTGTPASERRSATRSIVDSLDDVANLLSELLRLDPSLAGLNEQTLEVRYRLDDVIEGVRVYRDRLEFEPGRLEVIEDRLAELRDLAKKYRAADAAELLERLTSASDELETLHYSAEHIAELVQQEQQLLASIGLAAAELSRRRRQAGDELAGRIAAAMSDLAMPHVKFHVQVSQRSDPQGVLIDDHYLAFDRTGVDQIEFLLSPNPGEPLKPLAKIASGGESARLLLAMKSILSAVDSVPTLVFDEVDVGVGGRAGHVVGEKLWGISDAHQVLCITHLPQVAAFGDCHFAIAKQVINQRTQTFVQPLSEQERIEELAAMLDGTPVSEASRRSASAMLERAANYKLATSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B877</accession>
    <name>A9B877_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3794"/>
    <dbReference type="EnsemblBacteria" id="ABX06430">
        <property type="protein sequence ID" value="ABX06430"/>
        <property type="gene ID" value="Haur_3794"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3794"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018339_0_0_0"/>
    <dbReference type="OMA" id="MDYGPAP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3836-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011408">
        <property type="entry name" value="Aldehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699:SF211">
        <property type="entry name" value="PTHR11699:SF211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036490">
        <property type="entry name" value="Aldedh_dupl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="32"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="531"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="783" mass="84560" checksum="DD2565356D8E2981" modified="2008-01-15" version="1">MSYGPAPEAAAPAHEWLDAHSRRFGLYINGTWTEVANERLFDSINPANRSVLAQVTQASSDEVNAAVAAAKAAFPAWSQTSGHVRARYLYALARQIQKHSRRFAVLETLDNGKPIRETRDIDIPLVARHFYYHAGWAQLQESDLAGYEPLGVVGQIIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTSLTALAFAEICHEIGLPKGVVNIVTGDGKVGEQIVKHPDIAKIAFTGSTEVGKIIRSATAGSGKKLSLELGGKSPFIVFDNADLDSVVEGVVDAIWFNQGQVCCAGSRLLVQENIADKLIGKLRTRMEQLRIGDPLDKAIDIGAIVAPAQLQKIEQLVAEGENEGSIKWQPSWACPTDGYFYPPTLFTNVAPASTLAQVEIFGPVLVTMTFRTPDEAIAIANNTRFGLAASIWSEDINVALHAAARVKAGVVWINSTNLFDAAAGFGGYRESGYGREGGKEGLYEYLKKSEVKKLKTKASPAPAPVATTASNGLPALDRTPKIYIGGKQARPDSGYSRIVVGSNGEQLGEVGDGSRKDIRNAVEVARSAANSWSAATAYNRAQVLYFLAENLGARAAEFAQRIRQQTGRNDADLEVETSIERLFTYAAWADKYDGSVHATPVRNATLAMVESLGVLGLVCPSEYPLLGTISLLAPAIALGNSAIIIPSPEHPLSATDLYQVLDTSDVPAGVVNIITGDRDSLAKVLAEHNDVDGLWYWGSAEGSAMVERSSIGNLKQTWVNYGETRDWLDRRVGEGEEFLRHASQIKNIWVPYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8C1</accession>
    <name>A9B8C1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3838"/>
    <dbReference type="EnsemblBacteria" id="ABX06474">
        <property type="protein sequence ID" value="ABX06474"/>
        <property type="gene ID" value="Haur_3838"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3838"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119559_0_0_0"/>
    <dbReference type="OMA" id="TGQIYHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3881-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="93"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="19027" checksum="8B2CF3A9C5D9D483" modified="2008-01-15" version="1">MDAAQALLDRIAALEARVSALESQTPVIPPIINQDLGLVRLLQQRTGSDYEHELGHGAFLFAGSINSALGNYVWQGEYGLGELLRYPAEQLISVLSALASPVRLQIIQTLLESPASSQSLLERLNMQSAGQLYHHLKELRNAGIITQRGRSDYTLEITALIPVMVILAAAKNIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D8</accession>
    <name>A9B8D8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3857"/>
    <dbReference type="EnsemblBacteria" id="ABX06491">
        <property type="protein sequence ID" value="ABX06491"/>
        <property type="gene ID" value="Haur_3857"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3857"/>
    <dbReference type="eggNOG" id="COG0587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001600_0_0_0"/>
    <dbReference type="OMA" id="NECRRMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3899-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="8">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1139"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1139"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1296" mass="143977" checksum="8BEC9C41F4E33389" modified="2008-01-15" version="1">MKDFVHLHVHSEYSLLDGYATTKAIAERAAELQMDSIAITDHGVMYGAMEFYANAKKANVKPIIGMEAYIAPNSNKDPMVKGGKNYYHLLLIAQNEVGYRNLVKLTSRSHLDGMGKGIFARPRIDRQLLEQYHEGLIVTSSCIAGEVIQQVQAKQRQKAIETVAWFRDLFGPENYFIELQLHNNTPELVEINEELVRIANEMHVPLVATNDTHFVRREDLDTHSRVMAMGFNLTLQELCSKNYQMDETYHIMSGDEMWDRYKIYGTAPMENTRRIADMCNLKLDFGRVELPEFDIPEGHDAASYLRLICEEGLIKRCNGNPTEEYVQRLSYELDVINQTGFPDYMLIVWDYVKFARSNGIPCLPRGSAGASLVLYCLGITDVDPVQNKLLFERFLSPERLEMPDIDTDFADARRGEILDYIATKYGRENVAQIITYGTLGAKAALRDMGRVLDIPLSEVDRVAKLIPTLPVGMTIAKSLDKVPELKQIYDTDPKLRELMDWAQKVEGRMKSVGTHACGVVVSRHPLENMVPLQRTTKDEHGVMAAFEGPTLAKMGLLKMDILGLTNLSVAAEALQLIEQTTGKTMWLSDIPLDDKKTFEALGRGETVDVFQLESAGMTRYLVQLKPTRVDDLYGMVALYRPGPLEQIPVYIHNKNNPHAIKYIHPILKPILEDTYGVIVYQEQIMQLLQAVAEYTLGEAYIVIKAISKKNKELMAENSVRFKEGCLRKGLTQAQADELWELILPFAGYSFNRPHSTLYGLLSYQTAWLKNNYPTEYMTATLSAASGEIDEVAKSVAEASRLGVAVSPPDVNGSKEGFTIVDIAGELPEGIKYNRGIRFGLSAIRNVGVGPIQAILKVRDESGPFSSIEDFCARVDRGVLNKRVMESLVKCGAMDSLPGTRHQKLAILDRAISAGHETQKAREAGQNSLFDMLGGGEQTSTPTISPIPFPPAATGLEMQRELLNWEKELLGMYISEHPMAQALANAPHDPGRISLGMIDKKHIGTTIRLIGMINNTKRIQTKKGDSMLVGKVEDLEGEIEFVAFPRTLEQYAELLVDDAIVQITAKVDNRRDEMQLMLESVTAFKVEQTTNKAAPAATVAVRRSVGAVEAMPEYLDDGAPMPEEPFHDDVYVEVRPAMSTPSVNSAPANSNGNGYAASNGNGNGHYPNGNGNHSNGNGHAEAAPAAVTIVPRPRRKVSVAPTAAPEDSSNVAIASGPRYHLHIYLPRSGNTETDIRRMQEIDRVLRGYEGDQPITIYLPNPMGQVMLEPSYRINPQEGLLSNLYSMLGQESAVLEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G4</accession>
    <name>A9B8G4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gpsA</name>
        <name evidence="15" type="ordered locus">Haur_3883</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 11">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3883"/>
    <dbReference type="EnsemblBacteria" id="ABX06517">
        <property type="protein sequence ID" value="ABX06517"/>
        <property type="gene ID" value="Haur_3883"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3883"/>
    <dbReference type="eggNOG" id="COG0240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_0"/>
    <dbReference type="OMA" id="NRMFGNM"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="13">
        <location>
            <begin position="7"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="14">
        <location>
            <begin position="183"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX06517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="35656" checksum="24883EDA9B36E06E" modified="2008-01-15" version="1">MNQRLDVAVIGTGNWGTTLALVLARGGRNVTLFGRNQAEVAQLQAAGENSRFLPGQRFPANLGLACDLALAAQAQVILLAVPSKTIRSNALQLAPQLVADSIILSCAKGIESGSLETMSEVLAEALAPHPRGLIGALSGPNIANEIAQGLPATSVVALSDDQAGQRAQSLLTTNLLRIYRSSDVVGVELGGALKNIVALGAGICDGMGLGDNAKAAFITRGLAEMTRLGMARGAHPLTFAGLAGLGDLIATCASPHSRNRRLGEALARGQSLEMALAQLGQVAEGVNTTATARQLAEQYGVELPIADELYRVLFEGKSPQQAGLDLMQRDPKNELAGLQGLFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B901</accession>
    <name>A9B901_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase, P-type (Transporting), HAD superfamily, subfamily IC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_5188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="10 11">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10 11">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07815">
        <property type="protein sequence ID" value="ABX07815"/>
        <property type="gene ID" value="Haur_5188"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5188"/>
    <dbReference type="HOGENOM" id="CLU_002360_3_0_0"/>
    <dbReference type="OMA" id="GVHRMAK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5250-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0614">Plasmid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="714"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="747"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="837"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="870"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="903"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="9">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="930"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="936"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="950" mass="101624" checksum="69624512D8E3C041" modified="2008-01-15" version="1">MTSSHVVAIFQQPTDVVIAALNSDMSHGLTTVEAHRRHRQYGANELDAEPPIPAWRTFLAQFQNVLVIVLLIAAAISLVVWLYEREQALPYEAIVIVAIVLLNGILGFIQEARAARAVAALRALAAAEASVIRNGETVRIAATELVPGDILLIEEGATIPADGRVIQSIALHTLEASLTGESLPVSKDTDPLTTAASLGDRSNMLFSGTTASYGRGRMVVTATGMQTEMGKIAGLLRQTTSERTPLQRELDRTGKWLGIVVIGMAVIMIGTILLLEEVRDVKTIVAVLILGVALAVAAVPEGLPTIVTAVLALGVQRMARRKAIIRKLPAVETLGSASIIASDKTGTLTRNEMTVRTIVTASGRVEIVGIGYGPSGELRQTDDASSTEAMRSEVTATLSAANRANNAVVLERDGRWTILGDPTEGALIVAAQKAGLTEETLTARFPRVGEVPFSSERKLMSTVHTDSTHPERLLVFTKGAPDVLLNQCTAEWVEHAPRRLSEERRATLRTLNEQLAGEGLRIIGIASRVLPRDALDQAHALNDELEHDLVLLGFVGMIDPPRDEAKAAITRAKMAGIRSIMITGDHPKTAMAIAMELGIAGTTAAVTGAEVESLSEEALRTLVQECSVYARVNPEHKLRLVKALQQNGAVVAMTGDGVNDAPALKAADIGVAMGITGTDVSKEAADMILADDNFATIVAAVEEGRAIFVNIQKFLFFLLSSNIGEVLTMFGGVVLASVLGLSAGNDAIIVPLLATQILWINLVTDGTPALALGLEPANAAVMHQPPRPHGSSVIPRGMWIRILVVGVIMAVGTLLVLDAALPGGLIHGSQTMEYGRTMAFTTLMLFQMYNVFNARSYTQSAFSHPFQNPWLWGAVTMSLVLHMMVITVPVLQRAFSTVSLTARDWLTCLLVASIVLWVRELDKVGQRHRLRGTQGEHRGTTTNTETDHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A9B975</accession>
    <name>A9B975_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07889">
        <property type="protein sequence ID" value="ABX07889"/>
        <property type="gene ID" value="Haur_5262"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5262"/>
    <dbReference type="HOGENOM" id="CLU_2493649_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5324-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="86" mass="9772" checksum="F3254E91931A0F7B" modified="2008-01-15" version="1">MRHHESIECALDSANAETIELLFFVVYDHRNKLKEVEWCLQLLKVLVEADASFAPLMDTLGFGLRKTQGTIDEVQELLTSINGRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC2</accession>
    <name>A9AUC2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Magnesium chelatase</fullName>
            <ecNumber evidence="2">6.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0390"/>
    <dbReference type="EnsemblBacteria" id="ABX03041">
        <property type="protein sequence ID" value="ABX03041"/>
        <property type="gene ID" value="Haur_0390"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0390"/>
    <dbReference type="eggNOG" id="COG1239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016684_0_1_0"/>
    <dbReference type="OMA" id="FAIDCIQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-393-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="343" mass="38362" checksum="9931094CA8375FC7" modified="2008-01-15" version="1">MNELLPYPLLGIVGQRELKTALTLALVNPAVGGVLLSGPYGVGKTTAVRGLLDIMPLVKRSRCENNCPPDDESDLCPTCLDFLARGESRLKDDLMRLIELPLNARLEDVVGGLNERVAIEQQRVVLEEGVLARANHNLLYVDEINLLDHAVVDAILDAAAQGQTFVRRGAMVKLYQSRLILIGSMNPEEGRLRPQILDRLGLRVWVGPLPNARERLEIYRRAIAFRQDRTAFRMAYAQATTQLRLDVLKARELLPKVHLTKTAERYAMQVITQLAIPSHRAEIVLLEAARARAAADDRVRATPNDIKAVAPMALRWRQSPHLSDFLQQHETDEHLIAQALQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD8</accession>
    <name>A9AUD8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0406"/>
    <dbReference type="EnsemblBacteria" id="ABX03057">
        <property type="protein sequence ID" value="ABX03057"/>
        <property type="gene ID" value="Haur_0406"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0406"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_5_2_0"/>
    <dbReference type="OMA" id="TLECWLH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-409-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="103" mass="11277" checksum="380E11D90E775FCD" modified="2008-01-15" version="1">MSFHVVATLHDLADTPAIQIDFAGEQVGIFRCGTQYFATSNICTHAYAELHEGELDVDDCTIECPLHGARFDLASGRPRSLPATEPLKVYSLKIEGDQILLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI0</accession>
    <name>A9AUI0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0448"/>
    <dbReference type="EnsemblBacteria" id="ABX03099">
        <property type="protein sequence ID" value="ABX03099"/>
        <property type="gene ID" value="Haur_0448"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0448"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1029630_0_0_0"/>
    <dbReference type="OMA" id="SSQGWII"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-454-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="57"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="30344" checksum="4CE19E420E8B80D2" modified="2008-01-15" version="1">MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSHELRTPLTALLAHTAIVHNQQSEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELPLVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVLAHPDRLKQVWLNLLMNCLRYCRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQILARHHSTLQIESSTNPPTGTHIWWILPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL6</accession>
    <name>A9AUL6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1900"/>
    <dbReference type="EnsemblBacteria" id="ABX04543">
        <property type="protein sequence ID" value="ABX04543"/>
        <property type="gene ID" value="Haur_1900"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1900"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="GSMPRID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1929-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="37352" checksum="AB3E66B758BBDAB7" modified="2008-01-15" version="1">MGAPLLEVKDLKVEFKRPGGVVHAVNGVNFTLEAGQSLGIVGESGSGKSVTMLSLLGLIGRTGRVVGGSAMFNGVDLVKMAPRELQDVRGRDIAVIFQDPMTSLNPIMKIGAQITESMRMRKIYSAAEAKERAIELLDRVGIPQPAKRLNDYPYQFSGGMRQRVMIALALALKPKLLIADEPTTALDVTVQAQVLDLLESLQDETGMAMIIITHDLGVATNYCDNLAVMYAGEIVEMTTVDRLVEHTSHPYALGLLNSTMEIGHGKTAIQPIPGNPPSALKVHKACPFAPRCRFKSSVCQERKPELTTVEPNHLVACFHADAVVKAAQQGDDAAAEVMLNVAQPIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN4</accession>
    <name>A9AUN4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1918"/>
    <dbReference type="EnsemblBacteria" id="ABX04561">
        <property type="protein sequence ID" value="ABX04561"/>
        <property type="gene ID" value="Haur_1918"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1918"/>
    <dbReference type="eggNOG" id="COG1337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041901_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1947-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="513" mass="56382" checksum="2CC509A0864F5723" modified="2008-01-15" version="1">MSINATRIIRKRIIFKAELVLTSAAVFSNGDSDPIIDMMILRDSCEPQKALLPGSSLAGALRSYLKDITKDDTAIDKLFGCIGDEEVGEYFGQSRLLISDAVSREPIQAELRDGVRIDHATRTAADQAKYDLEVLPAGTCFSLELEFIVLEEVPTINLLPLVVQALHGLQTGQISLGMKKNRGLGQCSVKGWDIYEIDMTKPTEIFGWLERDDKNPIPTAAQHSNLYDYFGFQPADASRYPVTLTANFTFADDAMLIRSALQTNNLEDLINNPDDQTVSKKIPDPVHLQTRVDGTLQPVIPGTSWAGVLRHRALRILNTLKVATAEQQLDELFGFVIEQQAKAQASRIMIKDSIIQHPATEPLVQNRIAIDRFTGGAFDGALFSEMPVWKTDQTCVTLEISIKPPRPKKEAQQDQQKPEDTPQPDPKPTPKFNQAEVGLLLLLLKDLWTGDLAIGGTSSIGRGRLQGLEATLTVDGAEFCFKQATDGIGSLHITGTGKRDQLQMYVEAIGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN7</accession>
    <name>A9AUN7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1921"/>
    <dbReference type="EnsemblBacteria" id="ABX04564">
        <property type="protein sequence ID" value="ABX04564"/>
        <property type="gene ID" value="Haur_1921"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1921"/>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013584_3_1_0"/>
    <dbReference type="OMA" id="YNYYCLA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1950-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024937">
        <property type="entry name" value="Domain_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01348">
        <property type="entry name" value="Intron_maturas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="595" mass="68959" checksum="7751B389A4DF949D" modified="2008-01-15" version="1">MRTADTILAVIRDRGQRGLPLARVYRILFNEDLYLRAYGRLATKQGALTKGSTDETIDGMSMAKIHRIIADLRRETYRWTPVRRVYIPKATGKTRPLGVPTWSDKLVQEVLRSILDAYYDPQMSDHSHGFRPNRGCHTALKAIQRCWTGTRWFIEGDIAQYFDTINHTTLLTILAKRIHDGRFLRLIQTLLQAGYLHDWVYHPTLSGTPQGGVISPLLANIYLHEFDQFVEHTLIPAYTKGQRRKVNPAYAQMEQRISKLRRQREYASVTPLLKELRTLPSRDVHDPDYRRLRYVRYADDFLLGFAGTKVEAEAIKQQINVWLYDHLQLKLSTQKTLITHASSDPAHFLGYDIVTQQANSKQTGNRRIVNGRIALRVARATITAKCNRYMKNGKATHRPELLSETDFTIIATYQQEYRGIVQYYMLAHNVSHLHRLHWVMKQSLLKTLAAKHKTTSAVMRRKYLATQQLPDGRRMLCIRVFVEQPARPPLIAQFGGISLRRNPMAILNERPPQLWNVGTEIIQRLKAQECELCGSHEDVEVHHIRRLANLKRSGRTEKPQWMQRMITRQRKTLVVCSQCHHRIHAGKTLPQQITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV66</accession>
    <name>A9AV66_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0493"/>
    <dbReference type="EnsemblBacteria" id="ABX03144">
        <property type="protein sequence ID" value="ABX03144"/>
        <property type="gene ID" value="Haur_0493"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0493"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_3_0"/>
    <dbReference type="OMA" id="MQIMHGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-499-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="2"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="39904" checksum="858F665AF22E66A7" modified="2008-01-15" version="1">MSLFEPYTLPVSGVTLPNRLVLAPMTTYSGTPEGQISPGEVALLQRRAAGGFGTVITAACYVDRAGQAFINQWGCDNDDKLDSLRQAASAIKAEGAIAILQIHDGGRMADPKVLIEPAPRSASAVAAERQGSLEPRAMSAAEVEKSIADFVAAAKRAAVAGFDGVEIHGANTYLIQQFFSPHSNRRDDEWGGDLERRLRYPITLAKAVREAVGDQFIVGYRFSPEEIENPGITIEDTLVLVDRLADCRLDYLHISLWNYAAGSMRNPESTQRLSPLVIEKLAGRVPLMAVGSIETPEQAELPLHDGAELVALGRVALWEPDWPNKVKAGRSDLRQALPAKDGDVICSLPKPLYELLIQRTGWVKVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ3</accession>
    <name>A9AVQ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4021"/>
    <dbReference type="EnsemblBacteria" id="ABX06653">
        <property type="protein sequence ID" value="ABX06653"/>
        <property type="gene ID" value="Haur_4021"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4021"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054755_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4063-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="433" mass="49161" checksum="9CBFC72B1C5E9B49" modified="2008-01-15" version="1">MTSMVAASPNPLYAASAFVDVYPFVRQQESEEELLIGRVDTNNFIMLPKEAVEVLDDLAQGKSVGEAQALYAERYGEIPDLADLLEQLESEGFVQPLHSDTVRFGQQSPVTAATASANPNQPRAVRFHFTFFPIRLAQVLFSPILLVCYALFIGGAAAIVVAQPSIVAGWRAMVVDQQMALFTLIIMLHGFVITFFHELGHAVAARSRGVDVRFGIGRRLWVIVAETDMSGIWSIQRNLRFLPIFAGMIVDLLSAAIMVYLAFMHQRQIINLSDFGYILVRAFMWSYLLNLLFQFYFFVRTDIYYVLSTWLRCSNLMGDTANYMINRFNRLLGRAEVHNQAAIPERERKIIKRYAFFWLIGRMLAFYSLFFLTLPILWSYASILFERMFGSASAGMQVLDSILAAILIFISQAVGIFLWLWSLIRRKVSVDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS1</accession>
    <name>A9AVS1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4039"/>
    <dbReference type="EnsemblBacteria" id="ABX06671">
        <property type="protein sequence ID" value="ABX06671"/>
        <property type="gene ID" value="Haur_4039"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4039"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="DDPMMQL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4082-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="22"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="171"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27775" checksum="FAE55C350CCDB04A" modified="2008-01-15" version="1">MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIRLVDYSNPDIIVMDVDLPGVNGIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAYLSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMDSFRQLTMDTHTEHVYSPMSPREIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKIVQNDNSFSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT4</accession>
    <name>A9AVT4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4052"/>
    <dbReference type="EnsemblBacteria" id="ABX06684">
        <property type="protein sequence ID" value="ABX06684"/>
        <property type="gene ID" value="Haur_4052"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4052"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042894_0_1_0"/>
    <dbReference type="OMA" id="LMPLEWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4095-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="41592" checksum="7414631A9545FB5C" modified="2008-01-15" version="1">MAKKALVLSGGGGRGAYHVGVMQALVERGWMTDGQGPDIIAGTSIGAVNGAALASGMTVAQLRQRWLHMHSEDVQQLSSDLPSISRPLMRFLLRSILTSDEHGGDDQIEAETPEADRNLHSPSIWHKFRSIFSTTPFKSLLDTTPWRHTLSAWMNFERINSPAAPTLLLTATDVRRGTLRVFCNHKLDGQAQDQLNIEHIMASSSIPAVYPWTQVGEDMYWDGAVLANTPLGPVIEHAGGDVEIIVVMMTPWDADPNDGDQHLEAMPSDLAQSLWLTLDWALLASYRASFKLLKVYNQIAEAAQRLTAAAEKTGDQSLRWPGTMPYRVAEPLVIAPQKLMPLEWIVDYEGKNHQALFEMGYRDALRAFDQRQEQA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV3</accession>
    <name>ATPG_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpG</name>
        <name type="ordered locus">Haur_4071</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AVV3"/>
    <dbReference type="SMR" id="A9AVV3"/>
    <dbReference type="STRING" id="316274.Haur_4071"/>
    <dbReference type="EnsemblBacteria" id="ABX06703">
        <property type="protein sequence ID" value="ABX06703"/>
        <property type="gene ID" value="Haur_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4071"/>
    <dbReference type="eggNOG" id="COG0224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050669_0_1_0"/>
    <dbReference type="OMA" id="MQITSAM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000134162" description="ATP synthase gamma chain">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <sequence length="295" mass="32342" checksum="47975C18ECF3AAED" modified="2008-01-15" version="1">MASAREIRRRIKSVKNTGKITKAMELVSASKMRRAQRNVLATRPYADRLYDVMGELTLRSMGGGTKHPLLQPHPTVTRVALILITPDRGLCGALNSNLTRAAARFITDQKSQGRSVSVIAIGKKGRDFILRVGQKLDSEIIGLGDAPPLVDVLPAATTAINGYSPDASGNYDYDEVYLLCAEFVNTLVQRPKLRRFLPVEAPGNAGATKVDYSYEPSQEDVLDQLLPRFIEVQLYQAILESIASEHSARMMAMRNANDNAKELVRDLTLTYNKARQAAITTEISEIAAGATALNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW56</accession>
    <name>A9AW56_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2065"/>
    <dbReference type="EnsemblBacteria" id="ABX04706">
        <property type="protein sequence ID" value="ABX04706"/>
        <property type="gene ID" value="Haur_2065"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2065"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="FYFDPFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2093-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="27879" checksum="4F17EC88B37A9052" modified="2008-01-15" version="1">MAIVDRSPWAVAGEHVQIGYGSGTRVALDAPSIRLKRGTRTALIGPNGAGKSTLLKAIVGLQPLTSGSMTVLGYPVGTCQQRIAYVPQRRDVDWRFPITVNDVALMGRDVHRRWPRRPQRTDYAIVREALEMVGMNAWAHHPIAALSGGQQQRVFLARALAQHAELLLLDEPFVGVDTATEAIIHRVITRLISTGCTVVVATHDLASIQTHFDAAVLLQQRIIANGTPLDVLQPSLLAEAYGGPLALFVGKDSHGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW71</accession>
    <name>A9AW71_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2081"/>
    <dbReference type="EnsemblBacteria" id="ABX04721">
        <property type="protein sequence ID" value="ABX04721"/>
        <property type="gene ID" value="Haur_2081"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2081"/>
    <dbReference type="HOGENOM" id="CLU_1141343_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2109-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="26961" checksum="3CF40605EAC126BC" modified="2008-01-15" version="1">MRTFMTNLADFLISNGLLPQAQGLTDAEITMVTAHVPCPIPAAYHAFLHTFGGSDTSRWCGGDDLGIAGVMAAHDVHQHMIHDGPMDWLGDPMVIPIMQYAGYTLYYLRADMGDDPPVLSVVLGDAPPPIAPTTEDSAFSRWVQDYALASIPNPTRHKTSRALLEQAWEVEAILAHTVQYRRFRDDVYRNATSHGIVPTPQAFMHTWAAIFCQTDLYHAMRARNMPIPFGWAYPPAEAADTHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA1</accession>
    <name>A9AWA1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2111"/>
    <dbReference type="EnsemblBacteria" id="ABX04751">
        <property type="protein sequence ID" value="ABX04751"/>
        <property type="gene ID" value="Haur_2111"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2111"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_0_0_0"/>
    <dbReference type="OMA" id="HIVWLIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="391" mass="41554" checksum="AD8EA24620520523" modified="2008-01-15" version="1">MQKQQLRLAQPEPKPAEASPPKSRFANHIAALQTQPSQAASRWQPSSKRRNIWLFGLLIVLSMVGVVLSLTWSSVDIPLSSVADILLGRPTAQPAWRTIIVDIRLPRIITAILVGMALGLAGLQLQTIFRNPLAEPFTLGVSSGASLGVALVILLAPSSGISFAALGSNVFGNLGTVGSAIVGGLSVLGIMMVVASRVRDMTIILLLGVILSAMTYALVTVLIFFANESQTRAFVEWQLGSFTRVRWGELRYFVPVTVIGALIACLTTKHLNALLLGEHYAQSSGINVQRARWIIMGSASIMAGTVVAYAGPIGFVGIAIPHLARGLFKTSDHRVLVPATILTGIPFALACGILAEVPSSSLQLPIDAATSLFGAPVAAWVLLRMKRGAWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX35</accession>
    <name>A9AX35_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2203"/>
    <dbReference type="EnsemblBacteria" id="ABX04843">
        <property type="protein sequence ID" value="ABX04843"/>
        <property type="gene ID" value="Haur_2203"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2203"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_6_0"/>
    <dbReference type="OMA" id="TIWIAIS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2231-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="150"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="41163" checksum="F4EF434CBC88D84A" modified="2008-01-15" version="1">MLILAVSAFAGSNSSFAQSRDVEKPVDIGDAVGLDLNAPAVPGQFVIKFKNSTSKASRANSLSALGAVQIDRIEALDAEVVEFASLKSNDSLAMRQAMVESLLKDGNIEYAEPNFIYTSTYTPNDPGRSSQWAWGVTQAYTGWDITRGSSSVVVAVVDTGIQSTHPDLDAKIVAGYDYIDNDSTPNDGNGHGTHVAGTVAAETNNSTGGAGTCPNCRLMGVRVLNNSGSGTLAGVANGITYAANNGAKVINLSLGGGGSTALQNAVNYAWGRGVFLACAAGNSNTSSTTSAYPAAYTNCFAVASTTSTDARSSFSNYGTWVEVAAPGSSIYSTWINSGYNTINGTSMATPHVAGLAGLLSSQGLTNSQIKSKICSSSDQISGTGTRWTCGRINIYKAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX50</accession>
    <name>A9AX50_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2218"/>
    <dbReference type="EnsemblBacteria" id="ABX04858">
        <property type="protein sequence ID" value="ABX04858"/>
        <property type="gene ID" value="Haur_2218"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2218"/>
    <dbReference type="HOGENOM" id="CLU_1774878_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2246-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="17020" checksum="B2015E11ECBDA766" modified="2008-01-15" version="1">MQMLRCVPHQRVLLATTPAQPSWRLKQTIIEYERYVRQIPNTERFAIVGMRLIPQPNRLISFRDLALRDGRFLAFDELRWAVHVVGQTLINVLAEQQVQGRLITGLHCDITACVVHPVDSAERHFVQTTRTILERCFNDAQLEQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX76</accession>
    <name>A9AX76_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome bd ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2244"/>
    <dbReference type="EnsemblBacteria" id="ABX04884">
        <property type="protein sequence ID" value="ABX04884"/>
        <property type="gene ID" value="Haur_2244"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2244"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_1_1_0"/>
    <dbReference type="OMA" id="TAWAYWV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2272-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="36127" checksum="21C4EFB3D699BEBA" modified="2008-01-15" version="1">MPLEVVVAAIGLLGVITYAILAGADFGGGIWDLLAWGPRRTQQREAIAHAVGPVWEANHVWLIFIIVVLFTGFPTAFAALSIGLFAPFHLALLGIILRGAAFVFRAYSPQKEQQPSQSSQRWGTIFGAASVITPVILGMTLSAVSAGQLRVIDGVVQSEGIVWMTPLAIAMGLLALALCAYLAAVYMTIETRDELQADFRQRALLAGTAVVGLSLLSLPLLYFTAQHLWEGLISVRAAPVLTIGLLAALLSGWALLRWRFQLARGAAIVQISCLLAGWGIAQYPYIIYPDITLATASAPRATLIFILVALPLGLLILLPSLWFLFKVFKSAPREDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB0</accession>
    <name>A9AXB0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4198"/>
    <dbReference type="EnsemblBacteria" id="ABX06830">
        <property type="protein sequence ID" value="ABX06830"/>
        <property type="gene ID" value="Haur_4198"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4198"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_43_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4245-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20483" checksum="DE939375C5E78A46" modified="2008-01-15" version="1">MAYPAQTDYPTIIRTAQRLIERDGVEQLALASLANELGIKAPSLYRYVANKNALLKGVVTVTIQQLFAAYDQVLATSPNDAQSQLVAISHGHRQFAHAQPKNYALALTAASPEQRADPALLVEMVLPIQAIMAQISGQEHSLAALRGLLGLIHGFVLLELNQQLQRGGDLSSAFDLAVRSYLAGLTTLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ8</accession>
    <name>A9AXJ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60 kDa inner membrane insertion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0764"/>
    <dbReference type="EnsemblBacteria" id="ABX03412">
        <property type="protein sequence ID" value="ABX03412"/>
        <property type="gene ID" value="Haur_0764"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0764"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036138_1_0_0"/>
    <dbReference type="OMA" id="LIVQLMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-776-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="34997" checksum="8E5B5FFD300B1227" modified="2008-01-15" version="1">MNFLGPIFLPFLEWLFHLFGNLGWAIIAFTILVRLGMLPLTLKQLRSQRKIMVIQPKLRELQRKYSKDREKLTQETMKLYREHGANPVGGCLPLLISLPILFGVWQAIQLFGTSVPATAEQVQFLWLPRLTPLIENNVTVNSAHDPYFILPILAIALQFITTLMAMQRNPDPQQASMNKVMMFMPFIFGFIYFQFPAGATLYSVTGSLIQLVQQYFTSGFGLLSKYLPFLPEKTGFLHQPLPESATITIEEPETPSDQPQRRDFWAALGKLEPVVDVSAAGATADSGSSDIAAEQAIEDVKAQLGKPKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK3</accession>
    <name>A9AXK3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0769"/>
    <dbReference type="EnsemblBacteria" id="ABX03417">
        <property type="protein sequence ID" value="ABX03417"/>
        <property type="gene ID" value="Haur_0769"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0769"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047487_2_0_0"/>
    <dbReference type="OMA" id="WSTENEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-781-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="33"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="48772" checksum="5612F65858A3C7E1" modified="2008-01-15" version="1">MGRFVRWLVFRLLRLYYPRIAVEGLEQLPRGRVMFVLNHPNGLLDPLLLMLILGQPVAFLAKNTFFNNPIGRWMMQSFGALPIYRQRDAAEGSNTRDQNEQTFARCRQLLADNRYLALFPEGTSHSEAYLLPLRSGAARIALGAEAEHNWQLDLNIVPIGLWYEDKHIFRSSVLLLVGKPIHVAEFQHAEAEREQAVASLTARMAEHLGGVVFQAGNAELLRGLPVMVGWTVDRLRRKRPSGREAYTSLTPTERVQLATLAAKAQRYARTLRLLGIADPWSPQLPLATRWRFWRKFLWTALAFIPAACGIVLSYPMYRLSGIIATRMTKELELLSTLKLIAGIVLQPIGWIISSLIIGLLTIWQAGVIVLVLAPLFGFIALRWSERWRAVREATAASWLRLTQPDLTTQLLQRRRDLGEQISNTILSLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT3</accession>
    <name>A9AXT3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ethanolamine ammonia-lyase small subunit</fullName>
            <shortName evidence="4">EAL small subunit</shortName>
            <ecNumber evidence="4">4.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">eutC</name>
        <name evidence="5" type="ordered locus">Haur_2259</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ethanolamine = acetaldehyde + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15313"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57603"/>
            <dbReference type="EC" id="4.3.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
        <text evidence="4">Binds between the large and small subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine degradation; ethanolamine degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EutC family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2259"/>
    <dbReference type="EnsemblBacteria" id="ABX04899">
        <property type="protein sequence ID" value="ABX04899"/>
        <property type="gene ID" value="Haur_2259"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2259"/>
    <dbReference type="eggNOG" id="COG4302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068224_1_0_0"/>
    <dbReference type="OMA" id="ADRNCVS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2287-MON"/>
    <dbReference type="UniPathway" id="UPA00560"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008851">
        <property type="term" value="F:ethanolamine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00601">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009246">
        <property type="entry name" value="EutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042251">
        <property type="entry name" value="EutC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042255">
        <property type="entry name" value="EutC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39330">
        <property type="entry name" value="PTHR39330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05985">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018982">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 4" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="2 4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="28068" checksum="284BFA907BC9DB18" modified="2008-01-15" version="1">MAEQSENELWQRLRQFTNARIGIGRVGDALPTKANLAFQQDHALARDAVHAQVDFAAIASALQPEFPQILRLKSAALDRATYLKRPDLGRSLHVESRLQLEALQTDPCIVALVVADGLSAVAIERHAVPLLNIIKPQLESLGWSLAPLVLVEQGRVAIGDEIGELLKAELVVILIGERPGLSVADSLGIYLTYAPQRGRNDAERNCISNIHPQGLSYVAASDLLMYLLGQARQRRLTGVALKDERQQLGATNNPTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXV4</accession>
    <name>A9AXV4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2280"/>
    <dbReference type="EnsemblBacteria" id="ABX04920">
        <property type="protein sequence ID" value="ABX04920"/>
        <property type="gene ID" value="Haur_2280"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2280"/>
    <dbReference type="eggNOG" id="ENOG5031GYT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_986382_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2308-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="32940" checksum="1D62443115755194" modified="2008-01-15" version="1">MQSIDKLFVNREKQTAGFVKMVQGETPKRIMMIEAGGGLGKSWTVEFMRAECQRRGIPNTEIDFADSVVYDYLAMLRRARDGLGPAAFNQFTQALNEVTQPTVRIETGTANTNAINNLLGQGNTFSGSNVNVGEVVAGNVIKDNSFVINADNAVVRQALQDRLTLAFFECLTALAAQGPLCFFFDTYDKVTVEAEAWLMGHLLPRVRDGLIQNVVVVIAGRSVPKLDNQWDRMIARTGLDLFSEPYVKEYLVQRRGLIDDPNVIKALFQGSTGQPQLLAMLADNILRSQDSGGDDDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXZ0</accession>
    <name>A9AXZ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2316"/>
    <dbReference type="EnsemblBacteria" id="ABX04956">
        <property type="protein sequence ID" value="ABX04956"/>
        <property type="gene ID" value="Haur_2316"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2316"/>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952401_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2344-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="31412" checksum="A56E429C033990EC" modified="2008-01-15" version="1">MHNDKHISQALTSIAEHEVPEGSLNLLKPIQAQVALKPQATRRVGWLRPAMMAACGVALAAVGFGLLPSQVNQVSAQEALRRAEQVTAFGLTGIDSLHGVLETHVPGTGSVVSEKIWVQQPNKLRKEIIWPSGNTMPEQYETQIMNGDDAWAWISPAGQPNLVDGTVSQFAASELDGALYVIPNPTASLDSNGNSEGLCAQPGDQLSTVGQESFLGRDALVIECVIGGDSDQANTRLKFWIDDELFVVLKSEYYETNGDLFVESAYTEFEVNGSYPADFFAPPAGAPIDVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY31</accession>
    <name>A9AY31_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4281"/>
    <dbReference type="EnsemblBacteria" id="ABX06913">
        <property type="protein sequence ID" value="ABX06913"/>
        <property type="gene ID" value="Haur_4281"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4281"/>
    <dbReference type="HOGENOM" id="CLU_362386_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4333-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735098" evidence="1">
        <location>
            <begin position="34"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="771" mass="82173" checksum="0DF9E386547BD88A" modified="2008-01-15" version="1">MKPTTSKKSIGLLCILVASLFASMVSNRTPVTAAPNAVGWGQAQLVAAGALKNLHSDVVIDANGKTHITWIRLAASTSDPSEVMYTNNVSGTWLNPYIVNGNAGHGADPFVSMAIEGNRAHIIFINFEGFAVHRYITFSASGITPSVATVLSSTKSSTPEIIADRTGKIHAFWGDRRASSAAQIIHRIWANGAWETGTGGRVVRNDGSNQKYPRATATADGNIHLTYLGDAKFPYLIFNGTTWNVSNNLDSGKVKIASLTSKGNTVIAVYSMAPSTHIVYYKQGTNGTWSNRVQLSSGTSYDEFPAVTYNDQTDRVYATWLSGPGDTAQALVAQEINPGIAFNPIQTIDAAIVGRAWPQIETRGGLVTAVWHHRTSSNQPFNVYRIDGNTGGQPVATETPTLSPTPTQPPVDFTLTRSSASPSNNPNVGLTITNMIGNPDQMRVSTTAFTAQSASPAWEGLNTSKTVNTGAGVTSCVTAVYVQLRNSSNGGVSSVQAVSASIDSAIQSTPQIYTMETAPSARPASLEQVQSQPFAPDRVSEKYTRNMTFAYTIAQETGGCSGITRHKAGPFVVNGSSYPYTGFSAFDRFVTGNDSSGTGFEEQTVNATVILTDTLGNQSTTTKQFTYDDDAPVLTAGGSISLPNGANTNVSVIPLEFTAVVTDDGFMNSAPADKRYWGVWVVATTSSTFPAPQDFLQYGDVIGLGDGTNRVDYVRLVNALTGTQSGTRFVHIRFLDGAGNYTETGLTSQAITLQPNYTGLPNYLPLIYKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY54</accession>
    <name>A9AY54_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">THUMP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4304"/>
    <dbReference type="EnsemblBacteria" id="ABX06936">
        <property type="protein sequence ID" value="ABX06936"/>
        <property type="gene ID" value="Haur_4304"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4304"/>
    <dbReference type="eggNOG" id="COG1818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2933">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047822_0_0_0"/>
    <dbReference type="OMA" id="LVCDMSW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4356-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="2">
        <location>
            <begin position="57"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39690" checksum="DCCBD40B84F59E85" modified="2008-01-15" version="1">MLDTYRVLISAAPEMLEAAIDEIRYGKYGVAVQRLAPEVALVELEQPLAEWHAFLLKRPAIFVRHIAPVHREVVLEGTPDDLERLTQVALNLAPHLPARKPFAVQTRLLDEHVKLTRFEINQALAEAVSQVSGLPLDVRNPQGVLSVALSMDRAYLGVSTVEFNRSAWAGGAHRFAREQGQLSRAEFKLLEAQALFNIEWPDHGQALDLGAAPGGWTRILRRAGLPVVAIDPADLHPSLRYDQGVRHLQILAQRFLPTQERFTVIVNDMRIDARDSAWLMVDSANALTNDGLAVVTLKLPHEHSAQIAYHSLSILRTAYWVIGARQLFHNRSEVTAVLRKKHEKRPKPEQLPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT4</accession>
    <name>A9AYT4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Beta-glucosidase</fullName>
            <ecNumber evidence="2 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="2 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2422"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05062">
        <property type="protein sequence ID" value="ABX05062"/>
        <property type="gene ID" value="Haur_2422"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2422"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_0"/>
    <dbReference type="OMA" id="WHVCEHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2450-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="412"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="474" mass="53724" checksum="6295716186C19F14" modified="2008-01-15" version="1">MTTVEQHFPADFMWGTATSSYQIEGAVHEDGRGESIWDRFSHTPGKTKFGQTGDIACDHYHRYPEDLDLMRELGLGSYRFSLAWPRLFPEGKGKINQAGLDFYKRIIEGLHQRHLTPMATLYHWDLPQALQDKGGWMNRDTALRFAEYAEAMYRQLGESVPFWITHNEPWVAAFVGHFQGRHAPGIKDLPSAVKASHHLLYSHGLATQLFRESKLAGQIGITLNLTPAYPTHDTPDDHAAAWRNDGYGNRWFLDPIFRGSYPADTVEWFQQHHQIEMDYVQTGDLAVIQQPIDFLGINYYFPNRISAADESKFLALVNSPAIGETSFRGWEVVPAAFADLLKRVQRDYGNTPIYITENGSAFADLKRAADGSVNDGDRMSYLHTHLEAVADAIAAGVPVKGYYAWSMLDNYEWAEGYDERFGIIEVDFATQKRTPKRTARWYQQIVANNGLPSLPADVQALAERYRNCPIGPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY6</accession>
    <name>A9AYY6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4394</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4394"/>
    <dbReference type="EnsemblBacteria" id="ABX07026">
        <property type="protein sequence ID" value="ABX07026"/>
        <property type="gene ID" value="Haur_4394"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4394"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010448_0_0_0"/>
    <dbReference type="OMA" id="GQGFYKK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4448-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="5">
        <location>
            <begin position="9"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
            <begin position="208"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ECH_2" evidence="6">
        <location>
            <begin position="504"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="804" mass="88290" checksum="E483DE1D26B4A862" modified="2008-01-15" version="1">MTYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNRIVQTGWDRVVKSSPAALMNKKAGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMARIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTHFFNPPRYLKLLEVIPTPDTDQAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTGTLIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQKSGQGFYKTVKGANGKEFWVLDWETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQDRGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFAKEMGPFEMWDAIGLADGVKLMQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTGKEVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGSDFCIGANIFMLMMAAQNDQFDQLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVSMHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITPAIKLAPESDPTPYLQRVFEQIGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAGRDGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFLALCREPKTMERIMFMLQNNKPLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYZ5</accession>
    <name>A9AYZ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4403"/>
    <dbReference type="EnsemblBacteria" id="ABX07035">
        <property type="protein sequence ID" value="ABX07035"/>
        <property type="gene ID" value="Haur_4403"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4403"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4457-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15971" checksum="8699BFA6462C6653" modified="2008-01-15" version="1">MIDPNFAHVLVVEDRDDTFFVVQDLLITEIGVRSCVRCRDGRSLITMLDAPTSGLFDLILYDIKRPLRDAFAQLPMLRVHPKLIGTRIIALTANIMPDDVERTRNAGFDGFIGIPVKQDRFPNQIWRILHDEWVWEPR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ32</accession>
    <name>LEUD_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="1">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM isomerase</fullName>
            <shortName evidence="1">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuD</name>
        <name type="ordered locus">Haur_4440</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZ32"/>
    <dbReference type="SMR" id="A9AZ32"/>
    <dbReference type="STRING" id="316274.Haur_4440"/>
    <dbReference type="EnsemblBacteria" id="ABX07072">
        <property type="protein sequence ID" value="ABX07072"/>
        <property type="gene ID" value="Haur_4440"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4440"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_0_3_0"/>
    <dbReference type="OMA" id="AFTTHTG"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135810" description="3-isopropylmalate dehydratase small subunit">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <sequence length="196" mass="21164" checksum="9072DD1305F93F43" modified="2008-01-15" version="1">MQPINTFQAKAVALPIENIDTDQIIPARYLKVTDKNGLGEALFTDWRGEPDFVLNQPYAQGAGVLIAGHNFGCGSSREHAPWALQGFGFQAVISTYFADIFKGNALKNGLLPIVVDAPTLARLTEQCLANQTIDVSVDLENQQVHVAGETISFPIDAFSKHCLLHGVDQLGYIQAQETAIQAYEASHAARVNTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ89</accession>
    <name>A9AZ89_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0987"/>
    <dbReference type="ESTHER" id="hera2-a9az89">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03635">
        <property type="protein sequence ID" value="ABX03635"/>
        <property type="gene ID" value="Haur_0987"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0987"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_3_0"/>
    <dbReference type="OMA" id="YRWMVRS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1003-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="33281" checksum="651508AC697B26E9" modified="2008-01-15" version="1">MELEHATALINGLNLHYVRAGSGPLVVLLHGFPEFWYSWRHQIPALAETHTVVALDQRGYNISDKPALWQHYTIDLLIDDVRALIEHLGFERATIVGHDWGAAVAWMFAMRYHGYLERLVIMNVPHPLLMAKGLLTNPRQMLRSWYMFAFQIPHLPEWSAKRNNFQVLTKALTGAVQRPGVFSAEDIQVYHQAWGRPGALRAMINWYRAYIRQGSRYLRQLSTHHIHVPTLLIWGTADTALGQELTYGTERYVTDLRIRYLSDVSHWVQQEAPNEVNAVLIPFVRGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZA1</accession>
    <name>A9AZA1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LPXTG-motif cell wall anchor domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0999"/>
    <dbReference type="EnsemblBacteria" id="ABX03647">
        <property type="protein sequence ID" value="ABX03647"/>
        <property type="gene ID" value="Haur_0999"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0999"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069060_1_1_0"/>
    <dbReference type="OMA" id="CFNENKV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1015-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025510">
        <property type="entry name" value="DUF4397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14344">
        <property type="entry name" value="DUF4397"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735352" evidence="1">
        <location>
            <begin position="27"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4397" evidence="2">
        <location>
            <begin position="31"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4397" evidence="2">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="23238" checksum="4CFA608A40F3D211" modified="2008-01-15" version="1">MVRRLMLMTLALLAVVGLSTPQASKAATMNYVRVMHASPDAPAVDIFVDGKAVLTSVPFFALSGQLALPDGTYTIDIAPAGAGVAASVFETKLTLEGGYTGTVAAVGSLGLGNFDVKLYEDNYSMTGAGMSRVRVIHGSPDAPAVDIKIAGTQNVVVKGAKFGDAATLEVPAGTYSFDISPAGSSTVLFTTPALRFESGWGYSLVASGFASKNFWVQSRVDMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZC7</accession>
    <name>A9AZC7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03673">
        <property type="protein sequence ID" value="ABX03673"/>
        <property type="gene ID" value="Haur_1025"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1025"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_5_0_0"/>
    <dbReference type="OMA" id="MQFGIEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1042-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="144"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="42461" checksum="C3048AE8F6C6CD52" modified="2008-01-15" version="1">MVRKLGFWGLNIGIWLAGMGLLGGLFGWNLAWLKDWQWLAEQTGWRFWLAQWIFRALVCLPLVFGLLLLLHPLWLGRRLLAATKANLMVEPSPNAETLSRRRFMLEAGLLGGLVGYSSVIEPFNPEIVELELPIANLPSRFEGFKIVQLSDLHVCAYTPAADVARAVALINQLDADIVAITGDFVDQHAKFADDATVPLRQLQAREGIFSVLGNHDYYTGDIDRMIWAIKRADLGLLINQQTVIRRGADRLNLVGLDDPKHDDGDGWSHSSIDLTRAFAKLSAGDPCITLLHNPIFAPSVVKSYGPQVILAGHTHGGQIWVPILTESAVRSRDRFVAGRYQLANSQIYVNRGWGFTGPPLRFGKRPEISVIRLTGQKIGNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF0</accession>
    <name>A9AZF0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Urease accessory protein UreF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureF</name>
        <name evidence="4" type="ordered locus">Haur_2456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2456"/>
    <dbReference type="EnsemblBacteria" id="ABX05094">
        <property type="protein sequence ID" value="ABX05094"/>
        <property type="gene ID" value="Haur_2456"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2456"/>
    <dbReference type="eggNOG" id="COG0830">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049215_4_0_0"/>
    <dbReference type="OMA" id="WREINFT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01385">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009467">
        <property type="entry name" value="Ureas_acces_UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="245" mass="26394" checksum="A1C1B9C8A5CE34C6" modified="2008-01-15" version="1">MPNIGDFWLGYTGVVMLTNAFAQLKLLQLADSALPIGSTAHSYGVESLVAEGQLGVAGLGQFMRAFIQESGQLEAYLANQAWQLADATAFDQAWLDLNDHAAAFKPARESRHASAVLGRRLLGLALQLEPLPRWQQASTLAQSHQIETHHSCVFGLVAGCLAIEAEAMLAALLQQMTLSLILACQKILPLGQVQAQQLLWQLHPTIKAVVAQTPHMMLADLAPCSIGLDGASMRHPLLGTRLFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF6</accession>
    <name>A9AZF6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2462"/>
    <dbReference type="EnsemblBacteria" id="ABX05100">
        <property type="protein sequence ID" value="ABX05100"/>
        <property type="gene ID" value="Haur_2462"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2462"/>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045518_2_1_0"/>
    <dbReference type="OMA" id="CPVHVAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2489-MON"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="3"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="30786" checksum="D6B8C4BAC413CF2D" modified="2008-01-15" version="1">MSRLLITGASGYLGQRVAYFAQQTTIWDKVYSQTWRNPPTAGEHVACDLADQAQLEALLEQIQPTAIIHTAAVTPAMGPAMTDQALWAVNVQASATLARWAAQHQVRLVHVSSDAVWGGREAAYTESDVPAPIHPYGASKAAGEAVVAALDPQAAIARTSLLYGQNPLDPNTTMALAMLRGERHGVLFTDELRCPVFVEDVAQALIELAQKPSLYGIFHLVGPQILSRFELGQALLAWNGIDSTGLPAGTTTASGLRRPSRVVVDNRTTQSQLSTILRSIDDVTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN6</accession>
    <name>A9AZN6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4458"/>
    <dbReference type="EnsemblBacteria" id="ABX07090">
        <property type="protein sequence ID" value="ABX07090"/>
        <property type="gene ID" value="Haur_4458"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4458"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005304_1_0_0"/>
    <dbReference type="OMA" id="SGCPYCL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4513-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="324"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="414"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="752" mass="84540" checksum="CEF708EF0C162BCF" modified="2008-01-15" version="1">MHEILFNSQVIAVREIYWNLPHAVEYVLYLFAIASIGTMFYKMYQDILLWRRGHATVRSTNFASRLWLTTTEVFGQKRVLRDRTPGIMHTFIFYGFLALFIGTDIIAAEADFTIPIAGEEQGKILTGGFYQYYELILDVMGMVFLAGLLWALWRRYKTKPTRLDNRRTDAWVLWSMIFIVVGGYFIEILRLANQTMTVGEGADAVTAIVYEQGWAKWAIFGYPGASVARAIGLGVERATDGTIVHSQVALWIHRVLWLSHMAVVFAFVGSIPFTKFRHIFYTPLNTLFRDRDPKGALDRIPNMEEELEKDEPKLGITTLSDFSWKRRMDFDACMRCGRCQDNCPAFASGSELSPKWLITKMSDLMHGGPVMKRDGTVVMVQPAGATATAPTTSNGVKIELLEGTPETLPLYEHGIVTENELWACTTCRACMTECPATIEHVDDIIDFRRNLTMVMGEIPSGVKTVLQGIERNGNPWKLPQRQRTAWADGLEVPTLAEKEEAEVLYWVGCAPSYDDRSKKTARAMVQLMQKAGVDFAILGDEETCTGDPARRMGEELLYEQQANTNIETMGQYKFKKIVTTCAHCYNTVKNEYPQFGGKAGVDYEVVHHTEFLNDLVEAGKLNPTVPVNEKVVYHDPCYIGRYNDIYEEPRNVLNSIPGLELVEAGPRNREKAMCCGGGGGNAWLEGFGDKHVNVIRLEQLQTEKPDTVAMGCPFCMVMFEDAAKNTNQSETLGRKDVAEILLQSVGEQPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP1</accession>
    <name>A9AZP1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4463"/>
    <dbReference type="EnsemblBacteria" id="ABX07095">
        <property type="protein sequence ID" value="ABX07095"/>
        <property type="gene ID" value="Haur_4463"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4463"/>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645108_0_0_0"/>
    <dbReference type="OMA" id="FEDTFWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4518-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="411" mass="45990" checksum="E273E313D9CC5061" modified="2008-01-15" version="1">MRAVWRYFSLFMIGILIVAGCSTTSYDNTLLTPGATANPPARTQLVIWHGADAQRSELFTRLLLEYQREHPNVVIQIVNRGANLLHDYRAALLEGTPPDLIWLNENRWVGELADQQLIIDLTERLSDENLESIAPAALDGARYGEKLYGLPLTLDLPVLYYNRANFVSTPPQSTAEWLEIARGFSDDQGQYGLAYNLSLYFTQPYLPAFGGAIFDTTGEVVLGTQSYTPTLQWLTWVDELAQDPRLLARDDHRLVARSVSQNSAIMTIDWADQIGTYRQLWGENVGVQPLPRLSQTGQEPQPFVRSSVLVISPRSTEQQQNAALDVMRFLVEMKAQTAFQAADIPSVRIDLASVDPLYTQIQLAVSRASAWPTTLRFNNGWDILIALVRNSLNGAPLEESIANADRLLRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B005</accession>
    <name>A9B005_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1064"/>
    <dbReference type="EnsemblBacteria" id="ABX03712">
        <property type="protein sequence ID" value="ABX03712"/>
        <property type="gene ID" value="Haur_1064"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1064"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_3_0"/>
    <dbReference type="OMA" id="FWMDNYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1081-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732285" evidence="2">
        <location>
            <begin position="23"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Spermidine-binding" evidence="1">
        <location>
            <begin position="194"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="373" mass="40621" checksum="CE34AED9285296E6" modified="2008-01-15" version="1">MKLRRFGLVLMVLSLLVACGEASSTAVPTTAPAGTATGSNAGSVDRSKLSKTLRIYAWGEYVPEDVPQLFESEFGVKVTVDTYSSNEEMAAKIRAGNSGYDLIQPSDYMVALLAEGNYLAKIDLANIPNIANIDPANMGLYYDPNNEFSVPYLWGTTGIAYDKTAVSPAPTSWSILFDPAQLSAYKGRVSMLNDEREVIGAAMLFLGKDRNSSDAADLEAAKKVLIEQKPLLAKYNSDNVYQDLASGEVVLAQSWNNYTGLAMIDNENIEWVIPQEGGVIWQDTMAIVAGTPNQYTAEVFIDFMNRPEIAAKVADFTGALTPNVKGEPLIGDDLKAVYPKIKPSAEDRKRLDWLRKGQNATAFSDVWSAVKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B044</accession>
    <name>A9B044_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1103"/>
    <dbReference type="EnsemblBacteria" id="ABX03751">
        <property type="protein sequence ID" value="ABX03751"/>
        <property type="gene ID" value="Haur_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1103"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="MIEYPIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1123-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="34865" checksum="75ACBA2307A5619F" modified="2008-01-15" version="1">MSGIAITAEGLTKVYKKIPAVNNLSLHIPEGTIYGFLGPNGAGKTTTIRMLLGLIRPTAGKATIFGHDILHARKHIAPYVGAIVESPAFYTYMSGLENLRVLARSGGQDLPQARYDELIEFVGLRGREKDKVKTYSLGMKQRLGVAATLLNDPKIVFLDEPTNGLDPAGTVEMRNLILRMGQEGRTVFLSSHLLYEVEQVCSDVAIIQKGVTIKQGRVRDLLATEGGPGYAIEAAPFERAMAILQELPQLKAHSFDQHWININAEPQDVPNVMRKLVQADVDVFQVVVRQRSLESLFLEITGTGGASAQQPLAEVVVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B048</accession>
    <name>A9B048_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1107"/>
    <dbReference type="EnsemblBacteria" id="ABX03755">
        <property type="protein sequence ID" value="ABX03755"/>
        <property type="gene ID" value="Haur_1107"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1107"/>
    <dbReference type="eggNOG" id="COG1533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_780494_0_0_0"/>
    <dbReference type="OMA" id="CEFGCPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1127-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Elp3" evidence="6">
        <location>
            <begin position="25"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="374" mass="42376" checksum="3EDE2614CF09566A" modified="2008-01-15" version="1">MAYYVEERPGGPALAPRRPTINEFFLSTYQVGPYVGCEFGCAYCDGWSFSQRPFNEVIRANVDLPDRFAEQLSVVSRGDLIAFSLGDAYQPAEKTYRLTRQMLQACQVAKQPVLILTKSLAVMDDLSLLQRMNEQGLAIVVMSIPTIDPLLSEKLEGKVAPPSARLEALNTLKRAGIPTGVAMLPVIPYLTDTDRQLPLTLNAIANVQPDFVVWEYLWQPNERHRQRITDLLSRLGNYPASYYRELYGKDMQPSLEYRREMHRDILGRFEELNLNPRAPLELYREHLAPNNVAALMLKHQAFIDQIKGRELLASRHSNLAEAVFNGKADEPALAVSPLWPMLREVLNISDTRARLDQILEKVRNPDTPNDPSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B1</accession>
    <name>A9B0B1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2582"/>
    <dbReference type="EnsemblBacteria" id="ABX05220">
        <property type="protein sequence ID" value="ABX05220"/>
        <property type="gene ID" value="Haur_2582"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2582"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1319464_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2610-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="120"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="23707" checksum="0C7A9727E466E89B" modified="2008-01-15" version="1">MAKQARFELFIDVYEKKQQVAQALTNMPTGELVESILKEFRRDFDFLGQNPDAYCLMKADGTVLSNNRTLDKQVSNKDRLIFSEAMPNMPADGQPMARRIYLREHPTGNSFRLHWQPAVVGRFDNQSNNDLLAVDLGSHPNGLRVSRRQFEITETGGHFYIESLSPNPTTITDSTGRPIQVDRRQVLQHGDLITLDRSQITFKVIISD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I2</accession>
    <name>SUCC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="1">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="1">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sucC</name>
        <name type="ordered locus">Haur_4569</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B0I2"/>
    <dbReference type="SMR" id="A9B0I2"/>
    <dbReference type="STRING" id="316274.Haur_4569"/>
    <dbReference type="EnsemblBacteria" id="ABX07200">
        <property type="protein sequence ID" value="ABX07200"/>
        <property type="gene ID" value="Haur_4569"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4569"/>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037430_0_2_0"/>
    <dbReference type="OMA" id="ITACDEV"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="chain" id="PRO_1000129195" description="Succinate--CoA ligase [ADP-forming] subunit beta">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <sequence length="378" mass="39640" checksum="B197B0987A735D1B" modified="2008-01-15" version="1">MKLHEYQARDIVARYGIPVTGGGVAATAEEVQKVAEQIGGPVAVKAQVHVGGRGKAGGIKLANTPAEAFDAGKAILGMDIKGLTVEKVLVAEAITFEKEIYLGVILDRATKRVVLIASSEGGVEIEEVAKINPDAIIKLAADPLLGLQPYQAQELAYSIGITDAKQARQFSSIATGLYRAFVENDAELAEINPLVVLPNGQLQALDSKIVLDDSGLFRHSEVAGMRDIAGEPESEIKARENGLTFIKLDGNIGCMVNGAGLAMATMDVVNLFGGEPANFLDIGGGANAQKVAAALDIILDDPNVKVVMVNIFGGITRCDEVAKGIVEAQKIIKRQVPMVVRLVGTNEAEGQRILADASLTPASTLADAAQKAVDIAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S7</accession>
    <name>A9B0S7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03797">
        <property type="protein sequence ID" value="ABX03797"/>
        <property type="gene ID" value="Haur_1149"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1149"/>
    <dbReference type="HOGENOM" id="CLU_975814_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1171-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="30849" checksum="2FC350342E28B5EF" modified="2008-01-15" version="1">MKLSKDTAHRLLSIGLALGVLTGCDQALPLPTTAINPTETVDAINATLHAQATAFAQSPTLEPAAEATYWADRNRESEYYAATVAAGRPTRTLSPDSADIATAKANGTLLTPFLSPVPRVIGRHYGCFDIPNRTITVHDCWFMVDNLSRYELVLYTKDADPSVSYILVETQTIQTQDVTTARYGTPRTIEPLYIHHTDGAQIYFATVANTTTVVLRFNLETRQWLDPNGTPIPVTATPTSIMPVPATPTSGGSTSTPRSAKTALLVVGTVTNTNVQRGFSRHKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B135</accession>
    <name>A9B135_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2675"/>
    <dbReference type="EnsemblBacteria" id="ABX05313">
        <property type="protein sequence ID" value="ABX05313"/>
        <property type="gene ID" value="Haur_2675"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2675"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_356331_0_0_0"/>
    <dbReference type="OMA" id="WMANVEN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2705-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732318" evidence="1">
        <location>
            <begin position="24"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="542"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="791" mass="87957" checksum="60907553237E49E9" modified="2008-01-15" version="1">MRRRISLLLALLAILFTTMPASAEIVNVPYFEEPELLLAEDELLKLAQLQDNTYPSVGTKISPDDTTVVIGNYRYSDTGSAFLNVVDGSIVPIQPLQLPEDSDFFPLAATEMVWLDNDNIGQVLYDLFMGGMVLSINRYSGQISLYPVNLPFLPLSIAPNGSRLLVVTFEASELEAMRQSPDSVKLPFNIEAPKTTMERTMPKDRIAYYSHTDSRRHMSEETLDLAIFDLTTGALTPLYSVPDHTLLYDYAWSKDGSKFALIRDTVILGEGFGEKRLVDVMTQDALGGLSPKDNPLFTENVLDIFDLTTGNFQPEAWRAVDGDGRVVRDIEWSTDGQRYIVRLERPAQIAGRPHPTYIFPDMASYQFRSVDGTLQRELYAPELQTPEASGFFYLSPDEVLFITANGTNQALYYFNQGSGEFRKVSNMDGTYFGVTTTNMSRQLIFSYMSFSQPADIYRLNWDGQALSRLTWANAELEKINNVRVDSVSFTVSSGAQRNGFLIQPAGAEFPPKDVPIVMWQEGGPRATMTQFFATNTENPYNLLPNFGIAVLYVPLPGRLGFGPEFLNALADNDNFGKIDIDEGAEIIGQAISRGWTSQNKVGVTGCSYGGYFSAQSITRHPTRYAAANPQCTLLNNANEFHFGLGPLIAYLEGGTPMDKPAEYAADSPLNRADRVRTPTLLFHGEYDFLPVKYAVDFHDQIEIQKHRVKLVTYELEGHGLSDPANQYRAAQEQILWFRQYLSGSPSVAAEPVVTDAATMTVPETTDVIVFTETATFAAPSLQFGKNLITAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B1</accession>
    <name>A9B1B1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ordered locus">Haur_4667</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4667"/>
    <dbReference type="EnsemblBacteria" id="ABX07298">
        <property type="protein sequence ID" value="ABX07298"/>
        <property type="gene ID" value="Haur_4667"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4667"/>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_2_0_0"/>
    <dbReference type="OMA" id="ARHGLFD"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="21401" checksum="0994D16B3E1D87B9" modified="2008-01-15" version="1">MARIATIERNTRETQIKLTLNLDGSGQVAINTGIGMYNHMLESFARHGQFDLAVTCNGDLHIDDHHSVEDVAICLGMAIDRALGDKAGITRTAHAYVPMDEALAFVALDLSGRPFHVLNFSWTNPSIGGLTCDLVEHVFESIAIHARMNLHAKIEYGRNDHHKAEALFKALARALDSATKHDPRLGDAIPSTKGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B9</accession>
    <name>A9B1B9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ordered locus">Haur_4675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4675"/>
    <dbReference type="EnsemblBacteria" id="ABX07306">
        <property type="protein sequence ID" value="ABX07306"/>
        <property type="gene ID" value="Haur_4675"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4675"/>
    <dbReference type="eggNOG" id="COG0166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037303_1_0_0"/>
    <dbReference type="OMA" id="IGVWYIN"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="464" mass="51019" checksum="700589B9E92C4FE6" modified="2008-01-15" version="1">MSTQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTSEIIAQAQAVRARADTLVVLGIGGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVDPELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREALAKRLGKDKLVDHLVLTTDPKKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQERDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGNVVNVGPTPIKSLGATDQHSQVQLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYLDGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTLGQFYYMLEMQTAFAGELYNINAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D5</accession>
    <name>A9B1D5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4691"/>
    <dbReference type="EnsemblBacteria" id="ABX07322">
        <property type="protein sequence ID" value="ABX07322"/>
        <property type="gene ID" value="Haur_4691"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4691"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331707_0_0_0"/>
    <dbReference type="OMA" id="WRIDNIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4748-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="863" mass="94735" checksum="76494B8B31BAB305" modified="2008-01-15" version="1">MSRYKLQTYQFGIVNGLRQDVSDRINSAMPNNLFAPEARKGHLFVLTDAVNEGARGKEACDLVTQTIIKAFYADTSFSITSGLRNALKTANTALYEFNFKAAHHQKTAVGCTCAVLRNNDLYIAQVQPTQAYIAHRGQLRALPTNPSWQGNVSSSTIMPPNALGTSLFSEPEMFRNVVEAGDMLVLCSSRLARVLGRADAERMFCLSEAAASLEELYAITRRNNLNEAHVALIDMLPFVDPNSELLSAEGLAERGKAAASVVGEWISDVTANAALMVRRDKDDENGEPSSAIDELPPMPAELEEVDPRDMGWLNERPRYRPRSLRDAEQWLPSSYLGETSMVAAIQAASSAPSIDLTDMEPLPIDFAAVPVPQRDPVVPLTGWQKFTAPFRYLLAAIVTFIANFGRSSRPIAPPLPRFAQARGGDLSYRRSRRRNIPWTLIALLIVLVGGGWFYVQDRRLQNTEAAYQDSLNVANAKFDAAVRATDDRAALEELGELDTHLETLGSDQGYMSNPTRKADYLALRKKSDNLRASIDRTSFLTDLKLVTTMPTSDTIGKLIVTPNTGKNDLYFIGTENGTLYSYSEGSSSPPISLLKDGDEIAGLPAAPIRSVMLREGELAAIDAPPNLNAQSNIYFYLSDTKTWVSRTIQGSELWTRQPFPDIETYGGGLYVYDLGRTDSATAGEILRYRSGEFANLPENWITTSTGDFNTKSVVDVAIDGRIYMLQPDGTVGIFEGGALIDTVTVPALDPPLRARRLFVEQEVSAETFRDNQGNFFIVDAVNQRIVEVNRQGEIVQQLKMPSTSTIKLELLNDVAVIGSGSSKMLYLANSNRIYSMVLPSPPPPRESLGGTTTTPTVQITPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J0</accession>
    <name>A9B1J0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1227</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1227"/>
    <dbReference type="EnsemblBacteria" id="ABX03875">
        <property type="protein sequence ID" value="ABX03875"/>
        <property type="gene ID" value="Haur_1227"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1227"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="EPLRTYY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1249-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="37553" checksum="3C84DC186ECF839E" modified="2008-01-15" version="1">MAVQNDTLLDINGLKMHFPVKSNGLLRRTIGAVKAVDGLSFSVKRGETLGLVGESGCGKSTTGRAILQLHRPTAGTVSFDGTDLTKLKGEAMRQMRRKVQIIFQDPYASLNPRMTVGDIVGEPIRVHGLRTGKEVRTRVEELLRVVGLNPYFINRYPHEFSGGQRQRIGIARALAVEPDFIVCDEPVSALDVSIQAQIINLLQDLQGQFGLTYLFIAHNLSVVKHISDRVAVMYLGKMVELAPSKELYANPMHPYTQALLSAVPIPDPEVEKQRQRIILQGDVPSPLNPPTGCHFHTRCPIVIDKCKAEDPPFQDYGGGHFVACWRATESQEQMNLKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R7</accession>
    <name>A9B1R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
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            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Brettin T."/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX05441.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="60" mass="6239" checksum="FB35232B423E9AAA" modified="2008-01-15" version="1">MNMSDPSEQPTPIEPPAPEPMPIGDPPLDPTTADPPPIGDPPSQPQPPIGDPPKSGEHKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B265</accession>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Pitluck S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Domin N."/>
                <person name="Martin K."/>
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                <person name="Lapidus A."/>
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                <person name="Glavina Del Rio T."/>
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                <person name="Tice H."/>
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                <person name="Bruce D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1379"/>
    <dbReference type="EnsemblBacteria" id="ABX04024">
        <property type="protein sequence ID" value="ABX04024"/>
        <property type="gene ID" value="Haur_1379"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1379"/>
    <dbReference type="eggNOG" id="ENOG502ZSEP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1330419_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1400-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="21251" checksum="E03758630CA18311" modified="2008-01-15" version="1">MAGVIGTVNQLTSPIWAGDFLDREHLMPGGATVDASQFLATDGAIVTLSANALVSATSIAVTALVNPIPANTLLRFAAGKYAYSTAAAAAGATSIAVEALPVALTSGDKATYKGSGTKPVTIVSGTLIGRTWAERDAGTAFGPAADADEEIYLLAFDISDASRNNDADLYRYNSIVKETFVPGWAGLSSTLKAFVRSHYQCTVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J5</accession>
    <name>A9B2J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04040">
        <property type="protein sequence ID" value="ABX04040"/>
        <property type="gene ID" value="Haur_1395"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1395"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1416-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13529" checksum="2C02C31043BA96BB" modified="2008-01-15" version="1">MLGLSSLLSQELASRNWSLRELATRSGIAVSTLSNLINKPDVMPDLRTLNALSISLNLPFRQLVEACGIPVDAHPTDEDATIQVLIAAVPEVRMFLNLLGQLSPDDRAAILSHLRWKVETSTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R8</accession>
    <name>A9B2R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05519">
        <property type="protein sequence ID" value="ABX05519"/>
        <property type="gene ID" value="Haur_2881"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2881"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_2_0"/>
    <dbReference type="OMA" id="MYREESE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2912-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17270" checksum="3303992239C2744F" modified="2008-01-15" version="1">MTTSREYAQQFIQLIDRTKRMPLDGAYAKIHELGLSHSHLRAMFILEHQPGLPMKDLAEALAMTPPSVTVLTRKLEASGLLERLPDQVDSRRVLLQLSADGSRMLAEMHNAHLDRFTQLLSGLSPSDQAQFLELMNRAVEALERMYREESEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U3</accession>
    <name>A9B2U3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05544">
        <property type="protein sequence ID" value="ABX05544"/>
        <property type="gene ID" value="Haur_2906"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2906"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329223_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2937-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735412" evidence="1">
        <location>
            <begin position="42"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="2">
        <location>
            <begin position="351"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="872" mass="91589" checksum="ECCAB64EA1A9B5B3" modified="2008-01-15" version="1">MAKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQLDPSGTPAAGGASTIATYWNADRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMMGIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYNNGIPFHYVAANLINTTGVLTGVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADVFVAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLKVNLTYDTTTETVTNKSATFVTPTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTRGNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTLPSSYTPINRNLRRASVGYPTGPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFDSSKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADVVLEYISQTTPIIPSIQDRLLDVTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTVTLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTVTIQIRVNGQGSASDTFVVVVNDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATNVYTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNSTLGPILFTVADIDDAAANLTVTAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTTITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B354</accession>
    <name>A9B354_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarylacetoacetase</fullName>
            <ecNumber evidence="4">3.7.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4887</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4887"/>
    <dbReference type="EnsemblBacteria" id="ABX07517">
        <property type="protein sequence ID" value="ABX07517"/>
        <property type="gene ID" value="Haur_4887"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4887"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026207_2_0_0"/>
    <dbReference type="OMA" id="YWTAAQQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4947-MON"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="PTHR43069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="SSF63433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="FAA_hydrolase_N" evidence="9">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="8">
        <location>
            <begin position="132"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="47083" checksum="317A7CC465FC0838" modified="2008-01-15" version="1">MLNETHDPALRSWVASANLAGADFPIQNLPFGVFRRQASHEQWRIGVAIGAEILDLSKAAEYLGELDQASLAACRAENLNQLMSLTPAVWSTIRLQLSRMLREGSSLQAELTPLLLAQAEAEMALPAAIGDYTDFYASIFHATNIGSMFRPDNPLLPNYKYVPIGYHGRASSIRVSGASIKRPHGQTKAPDAEVPTFGPCRLLDYELELGFWVGQGNELGQPVSIEQAEHHVFGVCLLNDWSARDIQAWEYQPLGPFLAKNFISSISPWVVTLEALAPYRCPAFERPADDPAPLAYLDSPANRSAGGLDLTLEVSLQTASMRQAGQAAEVLSLGNFSDMYWTFAQMLTHHTSNGCNLEPGDLLGSGTISGPSKNSRGCLMELTWRGQEPIQLSNGEQRRFLQAGDEVIIRGWCGASDGLKIGLGECRGVILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B387</accession>
    <name>A9B387_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1405"/>
    <dbReference type="EnsemblBacteria" id="ABX04050">
        <property type="protein sequence ID" value="ABX04050"/>
        <property type="gene ID" value="Haur_1405"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1405"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2699674_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1426-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8200" checksum="C90C7880B88194AD" modified="2008-01-15" version="1">MRRKPVSFTTVRLVWGAVSRRPLATVRDLADELRLGYSTVAQALLVLRDAGYIEFTPKRCGCRKIIIPLLEAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B392</accession>
    <name>SYDND_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="1">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="1">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="1">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aspS</name>
        <name type="ordered locus">Haur_1411</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B392"/>
    <dbReference type="SMR" id="A9B392"/>
    <dbReference type="STRING" id="316274.Haur_1411"/>
    <dbReference type="EnsemblBacteria" id="ABX04055">
        <property type="protein sequence ID" value="ABX04055"/>
        <property type="gene ID" value="Haur_1411"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1411"/>
    <dbReference type="eggNOG" id="COG0173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014330_3_2_0"/>
    <dbReference type="OMA" id="YQLDVEM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000091001" description="Aspartate--tRNA(Asp/Asn) ligase">
        <location>
            <begin position="1"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="1">
        <location>
            <begin position="199"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="537"/>
            <end position="540"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="1">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <sequence length="594" mass="67263" checksum="F63C6CBEC15D9836" modified="2008-01-15" version="1">MLRTHTCGELRRDHIDQTVTLAGWVHRRRDHGTVLFLDLRDRYGLTQVIVDPSSNPEARAMLDSIKNEYVIQVTGRVRSRLEGAENANLATGAIELEVQSAKILNTAKTPPILVNRDGGEDEALRLKYRYIELRRERQQHILGLRHRTIKFMRDWMDREGFWEIETPILMKSTPEGARDYLVPSRLHPGEFYALPQSPQQLKQLLMVSGIDKYFQIARCMRDEDLRADRQPEFTQLDIEMSFVEQDDVLDVVERLMTELVANVTPHKRLVSPFPRLTYADAIEYYGSDKPDLRYDLKFVNVGEIVKDSQFGVFTGALSSGGKVQAIRLPGCGSYSRKQIDDLQEVAKIGGAKGMAWMAIEADGSVRSPIAKFFEQAQLDQLKSATAAEAGDLIVYVADKPAVVAASLDKVRREMAKRLDLADKDLMHFAWVIDFPMFEYNAESGEWDAAHHPFCMVNPADVEKMQRGEFEGVRAASYDLVCNGYELASGSIRIHDRSIQQYIFDRLPYSPEEIQKRFGHMLEAFEYGAPPHGGMAPGIDRLVMLLADTDNIRDVIAFPKTQRAEDLMMNAPSSVDAKQLRELGLRLADGVEPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B395</accession>
    <name>A9B395_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dak phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1414"/>
    <dbReference type="EnsemblBacteria" id="ABX04058">
        <property type="protein sequence ID" value="ABX04058"/>
        <property type="gene ID" value="Haur_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1414"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_945846_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1436-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="2">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="30387" checksum="C51C9B8F9DFEE0E4" modified="2008-01-15" version="1">MSKALTDLFAEMTRNLADERDSLNALDGVGDGDAGDNMLSNFETITNTLRQNEGQGSVDQALRAASKALRTSGKGPTAPMYANGLEQAAKDLEGKTSFGVNDIVKLLGGLLGGVQNTPGVKQQGEGGILDGLVPGVTTFMQARNNGKSTLEALMDGYKASQRGAYGTTQQGSGFGQFGNNDTSGKVDPGAAGASSLFGSLLQTLLSNGLSAGRGEPTKTSGFEELFGGQPQQSQQPQQQQPQGGYGDALGGLGDLFGQLFGGGGLFGGQPQQPQQRPSSRGDDPQPRLRDQEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A4</accession>
    <name>A9B3A4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1423"/>
    <dbReference type="EnsemblBacteria" id="ABX04067">
        <property type="protein sequence ID" value="ABX04067"/>
        <property type="gene ID" value="Haur_1423"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1423"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_9_2_0"/>
    <dbReference type="OMA" id="DYIQEVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1445-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="13448" checksum="B2C5038F7341B7BF" modified="2008-01-15" version="1">MDISHKAYNRVDVITVSGRLAAETKDALNDKINQIFEENRHRIVLDLENLEYISSPGLRVLIEARKKAREWKFSELERGDVRIANLPQRIREVFDLTGFTPLFQIYDDLVEAVGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C7</accession>
    <name>A9B3C7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1446"/>
    <dbReference type="EnsemblBacteria" id="ABX04090">
        <property type="protein sequence ID" value="ABX04090"/>
        <property type="gene ID" value="Haur_1446"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1446"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105788_4_0_0"/>
    <dbReference type="OMA" id="HQRMAYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1468-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="23132" checksum="D44B4D9E09204C19" modified="2008-01-15" version="1">MPIMLPLNLTIEEPTLPDLTPFPQTGLVHWTSKLGVELAVRHITPDDAKLLVELYGRLSPRTLELRFATIMINIPIERVIEESARLATLNHDHADALIALLNEDGQEHIVAVARLAGADHIQAEFALLVRDDFQGHGVGSYMLDLLFQVALVRGLRYLKASVLAENTAMLRLIRRSGFPYHMHTSHGESDVTIYLDPTISEGEINHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3G9</accession>
    <name>A9B3G9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1488</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1488"/>
    <dbReference type="EnsemblBacteria" id="ABX04132">
        <property type="protein sequence ID" value="ABX04132"/>
        <property type="gene ID" value="Haur_1488"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1488"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="FIINVRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1510-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="26171" checksum="D6414325638976D1" modified="2008-01-15" version="1">MDYTILLIDDEAKLRQVIRLSLEQEGYRVVEASNGREALYRARIEKPDLVVLDLMMPEMNGTEFLLAFSKESNTPVIMLTARVEDHDKIIGLELGADDYITKPFNMRELIARIRAVLRRTHKPTLEPDLIRAGDLVLDRGSATVLVGEQQLSLTRSELEILATFMTAPGLIFSRLDLLDRLSLGDAYEGYERSIDVHIRNLRTKIEPDSRQPRYIETVYGMGYRFKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3I0</accession>
    <name>A9B3I0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NHL repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2914"/>
    <dbReference type="EnsemblBacteria" id="ABX05552">
        <property type="protein sequence ID" value="ABX05552"/>
        <property type="gene ID" value="Haur_2914"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2914"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008645_3_0_0"/>
    <dbReference type="OMA" id="HIYVCDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2945-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="163"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="218"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="315" mass="35065" checksum="00EFBF85B2678B66" modified="2008-01-15" version="1">MRRCLSFLLVGLLAGCSQQPQHLLRPNGVAVASDQHIYVTDRGNYRIAQLDSTGQIAASIGVFGVGPSNIHSGWDLGRDSFGRLYIGNFIYNDEATLVHDGVRSFEPDGSFVREFGGNDYDPAMDEPTNEPYGVTVDSADRIWVANYKANRVVVYHRDGQQLAEFFGEFGNGNEQFSGISDLVVDRERRHVYVVDSFNGRIQEFSLHEAGDTISLQFLRVIGRYGSNLGEFSYPLNIALDQATGDIYVGDMGNQRIQRLTHDGQPIAAFAPDLARWQVFGLAFHNNHVYAADAYNNTIWRFNADGSNPQRLGSEQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3W0</accession>
    <name>PANC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pantothenate synthetase</fullName>
            <shortName evidence="1">PS</shortName>
            <ecNumber evidence="1">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">panC</name>
        <name type="ordered locus">Haur_3460</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B3W0"/>
    <dbReference type="SMR" id="A9B3W0"/>
    <dbReference type="STRING" id="316274.Haur_3460"/>
    <dbReference type="EnsemblBacteria" id="ABX06096">
        <property type="protein sequence ID" value="ABX06096"/>
        <property type="gene ID" value="Haur_3460"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3460"/>
    <dbReference type="eggNOG" id="COG0414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_0_0_0"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000097075" description="Pantothenate synthetase">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>beta-alanine</name>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="180"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <sequence length="276" mass="30089" checksum="799FF0D743F2832D" modified="2008-01-15" version="1">MQVVTTIEEVRAARRQWAEVGFVPTMGFLHAGHLSLVQQSKAENGVAIASIFVNPTQFGPNEDFASYPRDTPRDLALLEAAGCDLVWMPSVEEIYPAGFSSYVEVEGVTAPLEGARRPGHFRGVATVVTKLFNVVQPTKAYFGQKDAQQTVVIRQFVRDLAMPVEVVIAPTIREADGLAMSSRNSYLNAEQRAAAPVLYRALTAAQTAYAAGQTDAEAIRQLMLETLAQEPLAQVDYVSIADPRSLQELTTIDQQGVLVSLAVRIGKTRLIDNLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3W2</accession>
    <name>A9B3W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3462</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3462"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="PL11">
        <property type="family name" value="Polysaccharide Lyase Family 11"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06098">
        <property type="protein sequence ID" value="ABX06098"/>
        <property type="gene ID" value="Haur_3462"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3462"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002616_2_0_0"/>
    <dbReference type="OMA" id="DGLMWGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3499-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10318">
        <property type="entry name" value="RGL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018366">
        <property type="entry name" value="CBM2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041624">
        <property type="entry name" value="RGI_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034641">
        <property type="entry name" value="RGL11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43118">
        <property type="entry name" value="PTHR43118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18370">
        <property type="entry name" value="RGI_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00561">
        <property type="entry name" value="CBM2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734544" evidence="4">
        <location>
            <begin position="27"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="25"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="773" mass="82631" checksum="053FB2D452257718" modified="2008-01-15" version="1">MNYRWRICLLLIATILSTFSYTNTNAQSGLSCQVNYALTNQWGGGFQADVVVRNTGTSAINGWTVAWSAASGQQIGQMWNATFTQSGTQVSAKNVDWNANIAAGGSQSFGFTATTTGSLAVPSSFTVNGVVCGGSVSPTATTPAATATRTPTSVPTATRIATSIPTATNAATSVPTATRAPTSVPTATPSTTTGRQMEKLNRGIISVRQGSNNFVSWRMFGTDLSAIGFNLYRGTTKVNSSPITNATSYLDSGAAANSVYTVRPVIDGVEQTASENSLNFANGYLDVALQIPAGGTTPDGVAYTYTANDASVGDLDGDGQYEIVLKWDPTNSKDNSQSGYTGNVYLDGYKLNGTRLWRIDLGRNIRAGAHYTQFMVYDLDGDGKAEVAAKTADGTRDNSGTVIGNASADYRNSSGYILSGPEYLTVFNGQTGVIRSTVNYDPARGTVSSWGDSYGNRVDRFLGGIAYLDGQRPSLIMSRGYYTRSVIAAWDFRNGSLTKRWTFDSNVSGSQYAGQGNHGLSIADVDQDGKDEIIFGAMTINDNGQPLWNTRNGHGDAMHVGDLDPSRAGLEVFKVSEDSSKPSSWFADARTGQILWQTAAGGDNGRGVSGDIWSGSPGAESWSSMDSNLRSVSGATLGRKPSATNFLIWWDGDPMRELLDATRIDKYGTSGDTRLLTGSNVSSNNSTKSTPALSGDILGDWREEVIWRTSDNTALRIYSTSTSTNRRIFTLMHDAQYRVAIAWQNTAYNQPPHPSFFLGDGMSNPPQPNIYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B479</accession>
    <name>A9B479_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH (Or F420H2) dehydrogenase, subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4982"/>
    <dbReference type="EnsemblBacteria" id="ABX07612">
        <property type="protein sequence ID" value="ABX07612"/>
        <property type="gene ID" value="Haur_4982"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4982"/>
    <dbReference type="eggNOG" id="COG0852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042628_6_0_0"/>
    <dbReference type="OMA" id="GERHNFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5045-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="2">
        <location>
            <begin position="49"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20139" checksum="5AA6511BD0CE328D" modified="2008-01-15" version="1">MALLARGELRSILQTEMPNALDTRWDTQATDQPEAHGEGQTILLDFDAVVKAEALVEVAHFIRDKFGYTLLSNITAVDYLKQGLIEVVYQFYNAAEGGPDLRVRVRIGRSPEECIVPSLTPTWPGADLQEREAYDMYGVVFPGHPNLARIYMWDEFKGFPMRKDFPKTGDKYTHVTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B495</accession>
    <name>A9B495_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Na-Ca exchanger/integrin-beta4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4998</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4998"/>
    <dbReference type="EnsemblBacteria" id="ABX07628">
        <property type="protein sequence ID" value="ABX07628"/>
        <property type="gene ID" value="Haur_4998"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4998"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_238100_0_0_0"/>
    <dbReference type="OMA" id="WQLQANG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5061-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026457">
        <property type="entry name" value="CSLREA_Nterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04214">
        <property type="entry name" value="CSLREA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1114"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1221"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1333"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1444"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1556"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="3">
        <location>
            <begin position="1668"/>
            <end position="1769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1800" mass="180334" checksum="79CCB76160E90694" modified="2008-01-15" version="1">MLQSPDQGRALRMQVRRRALVLNLALLLALFVVPLQPTAARIAAPQLPEASSASAPSAACTVTNTNDAVSPPVDSLRAALANAACSPILFDPSLAGQTITLTAGELTVGRLVVIDGAAAPGLKIDGNNASRIFNVNVTSANLLIYNLTLQRGKAPNSGITNGGAVLNQGGTVVISNTAVLSSTAGTSGNGGGLRNQRTSGIAGVLRVYNSVIRGNTAPNNGGGFSTSGSITTIVNSAVLSNTVTSTSGGVTGSGALGLGAGIHHVNIQNPAANLTTAITNTTIAYNRGKAGAAIYNDNNGMIDVYYSTIAYNAASNSSGSAVGGVINGVTTAGQPALRLSLYNTIVANNTQRAANTTLTSADLGVGTGQTITSNGYNLIETVPSGAVFGGTTATNITGQDPVLGDVLNNGGGTPTAALLQNSPAYNTGDPAPIAAPTTDQRGPGFVRVREGRLDIGAFEATNSIQTSPILVSTNLDTNDGACTTFDCSLREAITLANSTPQTDTIRFNLLGSGVRTISPTTALPAISAPVILDGLSQAGAACNAPLIELNGSLAGASANGLDVTGGSSLIRGLVINRFAGNGVRLATLGGNTLECNFIGSDASGTVDAGNSLSGVRVESANNLIGGSGGSNVRNLISGNDGDGITLVAGANANTIQNNYIGTMLSSNAALGNSKSGVRIASDNNQIGGTFGTLGNVISGNFEHGVLVNVTAAPLGNRIQGNFIGTNIGATLDVGNTQRGVFIDRTANTLVGGTTAERNVISGNNSDGVAIIEAGATNNKISGNYIGTNNGGGSALGNSSAGVYIFNVGGNTIGGTTTAERNLISANSNGIVIGGGSAIGNIIKGNYIGTTLNGNGALGNVSDGIKLDGARNTQIGGTTIGERNVISGNGNNGINIFTSSSSGNVIQGNYIGTNAFIPPASPTGVANQFNGVRVAAGTNTTIGGSAQGAGNVIAFNAKNGVLITQGAAVATTQRIQRNSIFSNNRLGIDLGPDNNANGDGVTANDANDSDTGPNNLLNYPIVESTSSGGGLTQIIGSYIGATNTALTLDFYSQGACDPSNFGEGQSYIGSFAINTGPTGAISYTANLTTTVALGQRVTATAVDGSGNTSEFSRCSSVGNLPSVSVNDVTLTEGNSGITQFNFTLSLSAVSPNPVVVDYVTADDTAIAPNDYTAASTTATIPANTLSIPVTIDVHGDTQFELNERFFINLLSATNAAIGDGQGIGTITNDDTAPSISVNEASANEGSGAPGQVNVPVTLSNASYLPISVEFITTDGTANESSDYTTITGTLNFAPGETSKTIAIAVVGDLIDEPDETINVALSNAVNTTISNDEAVATILDDDATPVLNVANGEVTEGNSGSVTVTLNISLSNPSSSAITVDYLTVGGSASAGSDFAISSGPLSFAAGETSKTVDVFIQGDMVDESDESFTLELSNPVNATVGSAGTVVILDDDAAPIINFVAPPMQEGNSGTRPLTVSLMLSAISGQAISVQYATHDNTALGGSDYTTISGTLTIPAGQLTQRFIVNVNGDLIDESNETFTVTLSNPQNASLLAPDAVATIIDDDGAPTINADAINVTEGDANSVNAVFNVSLSNPSATAVTVNYSTLAGTAASGTDFTPAAGTLSFAPGELSKTVTVVVLGDLVDEADETFTLVLSSATGGATLGSNGTATIVDNDPTPSASLSGLNSVVEGSGITTTLQFTVTLSAASGRASSLQFATTAGTASAGSDFVGQNLMLNFAAGETQKVVSVAIVGDRVKEPNESFSVAISNPSNLTLGTATISVTIVDDDEWLVYMPYVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B7</accession>
    <name>A9B4B7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02674">
        <property type="protein sequence ID" value="ABX02674"/>
        <property type="gene ID" value="Haur_0022"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0022"/>
    <dbReference type="HOGENOM" id="CLU_351895_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-22-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="799" mass="89175" checksum="26E10F146667D448" modified="2008-01-15" version="1">MDSQQQFTAASHLTADNLRSIAHSISISQVSRLSLPEIDAVVDQISRVVPAGNVPGVILSGLAKLTGRRPAGNVIKRDVNLLFRGVEQALDKAVFSTFFAGPAAVIWGYQKLLELAGKDPQDAFPEGTWQFYVGYALREDTARHANETIGFDETLNDHKINLPPIDRMTAWVMAAIHILHSYPDLLENEWRERVSLALLRDLTKVNPETRQFADLYNQWERQRPYGRGPDVQSQENYALYRKRKFDEFMAESTRDLPKEIRERWGKQFQRAREIALPAYQRQMALAAYLDPTPYNENMVALPRQSWHIGLIWRGHYYLIPACAPNSTRPNDVSSVRSQIAALLASPANHAPTSLIPLATTKRTILPSILGKLRPETSQQLEALRCAPIWFNADGRPRHLPLAELRLTERGLGDHGLTLIDTGSSMVFDQSHIFFDGAWGSAVAEIMTLEALAWAVYLRGQPAPVAGTVRPYAPNIELNDEEKQILADSPKIVAEASAESIGVDLKKILELRKLFKQRNDQIRITVNDILVLYRAIHAVSYKPNPELQASLQEASNDANLKAAVEATITAFEESLANPAILIPVDGSIPNPSDRLHPMTFEVPLEELEISKLHERALSLLDQARQEWRAEVWDTFEATQKHYLATIAGFGEVSARAKDIAQSGESTSSGALRLLAHVPMALQRLLDAIPGKFDVLNDLIKGREVLSNVGAVADTSSLTRFITAKDDNEKKTLAWGVITDANGVMHVSLRDFRPHVGLFVAAGRRDLARRIANDYLESYVNGLNRFISELTKITQGRHSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G0</accession>
    <name>A9B4G0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0065"/>
    <dbReference type="EnsemblBacteria" id="ABX02717">
        <property type="protein sequence ID" value="ABX02717"/>
        <property type="gene ID" value="Haur_0065"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0065"/>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546147_0_0_0"/>
    <dbReference type="OMA" id="FRWLIVE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-66-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="502" mass="57023" checksum="AB91D3CA2D99F2D8" modified="2008-01-15" version="1">MMLARWRWHPLTTLGLSGLAALAIVALYRPKRFVPLIGIDEAAAHNLLFALALLVLFALLAWLRPEIGLAGVAATIPFNYRSRGFWDGNYPFIDGKYFPLHELLLLVVLGVTALDVGWRLIQRQIAWQMWWREHWRMLLLPLAWLLVATFAANLAVPEGQAEAWREWRWMIIEPLLLYGLILYWQPRYPVRRWLLWGLLAGSVIVAIIGILQWRDLDWTPIDGTGMCFSDLIVDSGGTKRTSSVYCHPNNLALWMDRASMLAVVAAAWACWQWWRKRTWQTAIWSLLYLGASSLLLLSLMLTYSKGARFAVALVLIGLSCLPRRWWLPLITSAVLGGLLLYSSLSGPERLNVTGDSSSARLSIWRSATAMIIDHPIVGIGLDQFYFYFNPQFNRGYIEPRLAADPAERNTAHPHNLLLDLWLRVGIAGVLIFAALAWRSLRRTWQIWHSEQPERWLALAALAALMAGWLHGGVDQGYFSSDLAMVTWLTLGMIDSFTLKGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T9</accession>
    <name>A9B4T9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3024"/>
    <dbReference type="EnsemblBacteria" id="ABX05662">
        <property type="protein sequence ID" value="ABX05662"/>
        <property type="gene ID" value="Haur_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3024"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_1_0"/>
    <dbReference type="OMA" id="AFMAHPR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3056-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="32555" checksum="80276A5816B2F391" modified="2008-01-15" version="1">MTDHRPTIMLVHAHPDDEVISTGGIALKYHEQGARVVLVTCTRGEEGEIVDAELNTPENKARLAEIRDVELARAIALLNITDFHQLAYRDSGMINTPANEHPESFNKADLQAATGRLVALVRQYQPDVLISYDENGSYGHPDHIMAHKITVAAFHAAGDPSQFPEAGPAWEPKKLYYTAYRRSIWRKAWEYMQARGEKTPLDDPEADLSRYVDDPRTTTAIEIGQYLPIKLQSLLEHRTQIGPTWGFLSLPEELRGELLSHEHFALIESRVSLPEREEFETDLLLGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4U3</accession>
    <name>A9B4U3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3028"/>
    <dbReference type="EnsemblBacteria" id="ABX05666">
        <property type="protein sequence ID" value="ABX05666"/>
        <property type="gene ID" value="Haur_3028"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3028"/>
    <dbReference type="eggNOG" id="COG0634">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073615_0_0_0"/>
    <dbReference type="OMA" id="TMDWMAV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3060-MON"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="19"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20000" checksum="607CFF9D3F8A69FD" modified="2008-01-15" version="1">MHPDLERVLIDTATLQNRVQALGTAIAQATVNAPELVLVGILKGSLIFMADLMRSIGREVCYDCIAVSSYGASTESSGVVRLNKDLDLDITGKHVIIVEDIIDSGLTLKYVHDLLLRRNPAALEICALLNKPERRNVNVQVDYRGFDIPNEFVVGYGLDYAERYRNLPYIGVLSPRVYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V6</accession>
    <name>A9B4V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3041"/>
    <dbReference type="EnsemblBacteria" id="ABX05679">
        <property type="protein sequence ID" value="ABX05679"/>
        <property type="gene ID" value="Haur_3041"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3041"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546026_0_0_0"/>
    <dbReference type="OMA" id="FLERIWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3073-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="499" mass="55964" checksum="59D2E36033FB790B" modified="2008-01-15" version="1">MGFCWLVEELKPMEKQQTEGQKQAWWRLGLGGFLLVMMLGLMWPAFERGLARRPVLNLQTPDDGLEGTLLHESQLIRRDRSLYRPIVAEEFISAPYTPLHPMLLSFMPFDPERPFTAGRWISLLSMLAIGLIISLFVASHTRIWLLGLAVGACWLAFPPAQLWALRLKPDLFALSFTALGLLLASWREGRWFGWAAVCFGLAFLAKQTLAMAPLAVGLNLLLHDWRKGLKFGTLAVLAAGLPYLALDLVTAGWATRHIWGLHRSEWWSFDLMWKYVRLLGWSLPLVGLALLGLGLYWRHYAMRQAALYATLAPISLYGAGEVGAHHNHLLETMLAWCLAGGLAAGLLINLGLSKQGWRRAATALAIGGLLLQGWCLRQTPSWYGGEFGILDLARFVPYIQSKPGDVLLDNPGLAIAAGKPLIFDDPSTMGPAIESGVWPAHGFYESIRQRRWSLIMLPFNVQTDRRDATGRWTEESIRLIDEHYQLEFADIVFTYVPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B503</accession>
    <name>A9B503_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoH</name>
        <name evidence="7" type="ordered locus">Haur_3088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3088"/>
    <dbReference type="EnsemblBacteria" id="ABX05726">
        <property type="protein sequence ID" value="ABX05726"/>
        <property type="gene ID" value="Haur_3088"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3088"/>
    <dbReference type="eggNOG" id="COG1005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_1_0"/>
    <dbReference type="OMA" id="WSGWASN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018086">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00667">
        <property type="entry name" value="COMPLEX1_ND1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00668">
        <property type="entry name" value="COMPLEX1_ND1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="39083" checksum="C7088C450892335D" modified="2008-01-15" version="1">MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAVKLMFKEDIMPSLADKWVFIIAPILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGLLYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISYELAFGLSVLVPVMLTASRSADGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFLVIAAKIFFFLFLSIWVRASLPRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B504</accession>
    <name>A9B504_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3089"/>
    <dbReference type="EnsemblBacteria" id="ABX05727">
        <property type="protein sequence ID" value="ABX05727"/>
        <property type="gene ID" value="Haur_3089"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3089"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_40_1_0"/>
    <dbReference type="OMA" id="EQFSMIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3121-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="21218" checksum="D20F8982C06BB528" modified="2008-01-15" version="1">MLLRQTARLQLHVLEEYDAQRALEFYQANAEFRQPWSPTMDASFLTLDGQRERLRSDRISRDREQGLALWLTEIDQPELVGMVALRNIVRGAFWSCHLGYEIHNAYAKRGYISEALQAVVEYAFVDLRLHRIEANIMPRNQHSIGVVEKLGFEHEGLARKYLKINGTWEDHIHYVLLNAAVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B562</accession>
    <name>SYP_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="1">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">proS</name>
        <name type="ordered locus">Haur_3563</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B562"/>
    <dbReference type="SMR" id="A9B562"/>
    <dbReference type="STRING" id="316274.Haur_3563"/>
    <dbReference type="EnsemblBacteria" id="ABX06199">
        <property type="protein sequence ID" value="ABX06199"/>
        <property type="gene ID" value="Haur_3563"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3563"/>
    <dbReference type="eggNOG" id="COG0442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016739_0_0_0"/>
    <dbReference type="OMA" id="NCDYAAN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000199395" description="Proline--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <sequence length="566" mass="61144" checksum="940B667E93D7B8F0" modified="2008-01-15" version="1">MRMSSGFGRTLREAPSEAELAAHQLILRAGLARQLLAGGMALLPLGMRVFRRIEAIMHAELAAIGAGEFRTPVVHAASLWEQTGRYAQYGEAMLRFNNRNQQALLFAPTHEEAVAELARREVDSYRQLPSLLYQIHTKYRDELRVRGGLLRLREFTMLDAYSLDTDWAGLDMVYDRVALAFETIFERCGVRFTAVEADGGEMGGREPREYMAFSSSGEDSLVVCPLCSYAANSEVAVRGQAAANDDVVPAMSEIATPACTTIAELATFLQVSEAQTAKAVFFNSAEKGLIFVVVRGDREVNEIKLRAAAGVSALEPATLEQISAVGAVAGYASPVGLSNVTVIADHSVVGVGGLVAGANRTGYHLQNVVYGRDWQATVVADIANVEEGDACPVCGAALSLERGIEIGHIFKLGTRYTEALGATYLDPQGQAQPIVMGSYGIGLERLLQVIIEQHHDEKGIVWPASVAPFDLHLVQLGASATVSEAANQLYQQLSEAGLSVLYDDRNESAGVKFNDADLLGMPLRLTVGERGLKQNVVELRQRATGVVETIALDQVVKSIKNIEHRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I3</accession>
    <name>HIS4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="1">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisA</name>
        <name type="ordered locus">Haur_0156</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5I3"/>
    <dbReference type="SMR" id="A9B5I3"/>
    <dbReference type="STRING" id="316274.Haur_0156"/>
    <dbReference type="EnsemblBacteria" id="ABX02808">
        <property type="protein sequence ID" value="ABX02808"/>
        <property type="gene ID" value="Haur_0156"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0156"/>
    <dbReference type="eggNOG" id="COG0106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_1_1_0"/>
    <dbReference type="OMA" id="EWLHLVD"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135124" description="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <sequence length="240" mass="24853" checksum="230781531DF4A3DA" modified="2008-01-15" version="1">MQLIPAIDLRDGRCVRLVQGDFEQTTVYGDDPVAVAQQWEAAGAARIHIVDLDGAKAGRPTQTSTIAAITKAVSVPVQLGGGLRDAASIAAAFELGVSDVILGTVAVRNPELVAELVRQYGKAITIGIDARNGVVATEGWLASSRQRATELAEQMGQLGVARIIYTDISRDGTLSEPNYAQTAALVTPNGPAIIASGGIARVEHLARLAELGISGAIIGTALYTGHIDLASAIQTIEHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I7</accession>
    <name>A9B5I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdopterin biosynthesis MoaE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0160"/>
    <dbReference type="EnsemblBacteria" id="ABX02812">
        <property type="protein sequence ID" value="ABX02812"/>
        <property type="gene ID" value="Haur_0160"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0160"/>
    <dbReference type="eggNOG" id="COG0314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089568_1_2_0"/>
    <dbReference type="OMA" id="WPLQRVS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-163-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15143" checksum="CDEBB825B36D918D" modified="2008-01-15" version="1">MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQLVLLARQAQVQFGIGKVAIHHRVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVPIWKCEHWTDGSQEWVGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B625</accession>
    <name>A9B625_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05818">
        <property type="protein sequence ID" value="ABX05818"/>
        <property type="gene ID" value="Haur_3181"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3181"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3216-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731915" evidence="1">
        <location>
            <begin position="30"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="687" mass="74964" checksum="829A9A6FEBA2AD96" modified="2008-01-15" version="1">MARKPFRTLVSLTLALGVLMGGTLLSAVADQSATLPPINGIWDSSLGNSFQKAGSIHSLTVDPSNNLYVAGDFNFINQTEVNGLARWNGSTWQGYGLQPNDAGKIHKVLPFENELFAIGDFERLQQAQNKIARWNGTSFQPIGNGITGLLHRFSPDITVATLHSYSETLYIGGEFSQFAGEFAYAIGQWNGAVQPQATIFDGKVTSFASDADELIAGGYFTQIDGVDSRLARLVDNQWVSLDVGIANNAFTVYSANNTIYLVGYNLSSQTYRLYRWDGSSATSVGGPLDVAIDNLVVHGTDLYIQSNQQLLKLENDQWHAANLPVTITKLTALASNGSTLYLGGELLVNGNPSQIVAWNGTQAQSLASLTVIDDQHLVSGDAGRPVIIDYGIGSAQGSIQRWNGTSWETLATDTNDSFGISQFYRANDQLYSFFLEPQALATGQAASNVWRLNGTTWTSADINLQDSVYWYESGQQILAYLSQPQASQPITGILEFDGTSLNPRLQPAWFNRSDYLFFFENNFYAINLLNDVDSNFLEIQRWDGQTWQEIQFMEVPKARYSLKLWRGQLFMANTAGNFYEINPDGSLDEIATADGGIYTLAGRDDGSLYLGGDFSTIDAAATGLIASFDGTNFRGLVSQPNGRVISLSVDHNYVYVAGDFTKVGTVASLGVAVFAPTKQVYLPMAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B629</accession>
    <name>A9B629_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3604"/>
    <dbReference type="EnsemblBacteria" id="ABX06240">
        <property type="protein sequence ID" value="ABX06240"/>
        <property type="gene ID" value="Haur_3604"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3604"/>
    <dbReference type="eggNOG" id="ENOG5032YH0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_976217_0_0_0"/>
    <dbReference type="OMA" id="VIGNWRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3643-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019206">
        <property type="entry name" value="DUF2085_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09858">
        <property type="entry name" value="DUF2085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="32666" checksum="42458E34623E5EE1" modified="2008-01-15" version="1">MNERDLNRLVLEKAKQQVEARKAEREVIVQEARKPQPLPERDERPALWGLIGVLLTLTIAGLFLIPGNFTEKLSWVVHGVCSKEHTLSLGGTMMPLCQRNTGLYSGFLATIITLSLLGRGRAAKLPPLAIGIVLVLSVAWMGSDGFNSLLLDIGNYNLYTPQPILRILSGLAMGISMGSMLLFAFNISVRANARHDQRIIGSWRDYAILVAVAVCLFVLTQLASPFIAYPLAIFSTVGILSVMFIVNIMIIAMITRSENTVVRLSQLARPAIFASFMTAAEFGLLAWLRIIMERSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C5</accession>
    <name>A9B6C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02828">
        <property type="protein sequence ID" value="ABX02828"/>
        <property type="gene ID" value="Haur_0176"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0176"/>
    <dbReference type="HOGENOM" id="CLU_2369010_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-179-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="11326" checksum="8FB9F5DEF67A71E6" modified="2008-01-15" version="1">MHMRLPAAHTQLLRQLKDERSKLQDLVWELDDLEHAVADLEQHVCDTPDPSKHQELEQLRQRHDHIEDAVLYQMMYIDRLQERYDLLPYSAIPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F7</accession>
    <name>A9B6F7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0208"/>
    <dbReference type="EnsemblBacteria" id="ABX02860">
        <property type="protein sequence ID" value="ABX02860"/>
        <property type="gene ID" value="Haur_0208"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0208"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1169022_0_0_0"/>
    <dbReference type="OMA" id="MTHRLIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-211-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05829">
        <property type="entry name" value="Sortase_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042001">
        <property type="entry name" value="Sortase_F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734587" evidence="3">
        <location>
            <begin position="18"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="26538" checksum="384030B27D555F02" modified="2008-01-15" version="1">MRRILLIFVGWSLVACGGTTNNPSATAVASLEPTSQALVASVVPTNTIVATPAATPTRLPTQTVAPEVTSKPVELDTPTLNDQNAPPTAAPQPTADASNAPSQPVRIVIDAIGLDLAPVSVGLDQRNVPIVPKHDAGWYNLSAQPGQGENVVFWGHVLRWKDAPNVPAPFARVKDVAIDETITVYSADGSEYRYRVTEQVWVTPDQVQYILPVGSERLTLVSCIGDQVIVEGNLEMSHRLITIAEPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N4</accession>
    <name>A9B6N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1700"/>
    <dbReference type="EnsemblBacteria" id="ABX04343">
        <property type="protein sequence ID" value="ABX04343"/>
        <property type="gene ID" value="Haur_1700"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1700"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_0"/>
    <dbReference type="OMA" id="WFMQNFS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1724-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="11"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="31259" checksum="C46B6279E1F03D16" modified="2008-01-15" version="1">MTANNLILVTGGTGKTGQRIVARLQAQELNIRIGSRSASPSFDWHDQQTWPAALAGVQRVYICYQPDLAIPAAIDTIRAFCQLAVNSGVQHLVLLSGRGEPEAQACEQVVQTAGITWTIVRAGWFMQNFSESFFHEPLLNGQIFLPTSDIKEPFIDAEDIADVAVAALTNIEQHQGHVYEITGPRLMTFAEAISEIAQANGKPIEYQQIPLETYLGALREQQWPNEMLWLVEYLFSQVLDGRNAYLTDGVERALGRQPNDFSNFAREAAKRGVWQLTSISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6W6</accession>
    <name>A9B6W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3197</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3197"/>
    <dbReference type="EnsemblBacteria" id="ABX05834">
        <property type="protein sequence ID" value="ABX05834"/>
        <property type="gene ID" value="Haur_3197"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3197"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_371229_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3232-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07481">
        <property type="entry name" value="Peptidases_S8_BacillopeptidaseF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033857">
        <property type="entry name" value="Bacillopeptidase_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735493" evidence="5">
        <location>
            <begin position="24"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="176"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="7">
        <location>
            <begin position="650"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="749" mass="77926" checksum="0E1E57E6A02B878F" modified="2008-01-15" version="1">MRLIKPFILLMVLAGFCLPSASANPPDRLASKADSALLAKLNAGQQVPTLVLLQAQVDTNFADRLASKEAKGAAVVAALRQQAQRDQTPLLAELSNRGIQSEGFLSVNALYATLDLASAQWLAEQASVKQLIEDSIVVKVEKPVAETNPAPQAVNTTTWGVNYVKAPEVWAKGITGQGIVIAGEDTGVRWTHAALKSKYRGWDGTNASHDYNWYDGIRTSLGGTNPCGLALNVPCDDNSHGTHTVGTVVGDNGTGEQIGVAPGAKWIACRNMDAGNGTPATYIRCIDWMLAPFPTAGTSAQGDPSKAPHVVNNSWGCLASEGCTNTPSDGIQTSVQNVTNAGIMFVASAGNDGSGCATITTPVAIYPESFVVGSHTSTGAISGFSSRGPATNNGASRIGPDISAPGSSVRSATNGGDDVYGSSSGTSMASPHVVGVVALLWSARPELQGQVDLTRAILQETATAAPSTQTCGGVAGSSIPNNTFGHGYVNALNAIAPTLQGSITVDGTAATSATIRLENSVGVVEFGKTTGVYSTSLPAGLYSATVTVPNETPITRQVTIVKGQVATENFEFGDVTGTVSGHATLNGTGRAGVSITANPGNFTTETNANGDYNLALAPGTYTISSEFMALETQVATVTVVLNQTVIQDFDFATTQTINIQNFRFSPSPITVTLGTSILWRNLDASTHTTTRGQMPFIWDSGDLSQNQDYAVTFDQVGTFSYVCSLHGSMQGTVVVTPPMQNTYLPWTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B763</accession>
    <name>A9B763_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3710"/>
    <dbReference type="EnsemblBacteria" id="ABX06346">
        <property type="protein sequence ID" value="ABX06346"/>
        <property type="gene ID" value="Haur_3710"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3710"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_3_1_0"/>
    <dbReference type="OMA" id="DIHTWMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3752-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="361"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="629" mass="70943" checksum="EB6F2C132B47AC1B" modified="2008-01-15" version="1">MCGICGIVSTSLIEPNTVQAMNQQLMHRGPDGAGTWQTAHAQLGHRRLAIIDLVTGDQPFSSPDGAWQLVFNGEIYNFQALRQQLHGLGHQFRTNSDTEVLLAALIEWGEQAFSRLEGMFAFAAWHQPSQSLWLVRDSLGKKPLYYSQTKHGLIFGSEIKALLQYPELDHSLNPQALIAYLTYGYVPNPATWYANIQQLAPGHALVWQAGSIREWQWWQARQIAQRPRLNISDKAAIEQTRQLVRAAVERRLICDVPLGAFLSGGLDSSIVVAEAQALLGQQLHTFSIGFAGGGWYDESSYAELVAKQLGTKHQCFMVEPDAIAKLPQLLAHYDEPFLDSSALPMALLSQMTREHCTVALSGDGGDEVFAGYERFGAGLWTQRYQQLPRPLRQMLEQTIALLPQTKASSRLARLKRVLAKIQLPLAQGFPRWLMAFTPEELAAWGLPALQPSAAERFSQATQGVTDPLAQLICYNLGSYLPDDLLVKADRMSMAYGLEVRSPFLDQQLVEWALQLPANLHWRGGRGKWLLRQAYAERLPKIIIERPKHGFGVPLDQWFRQQLKPMLHDYLLSTTSHVQQWLPKPKLEQLCHAHWAGTMNAGHQLWTLLTLELWLQTHHQMRPYAHNYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C7</accession>
    <name>A9B7C7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3774"/>
    <dbReference type="EnsemblBacteria" id="ABX06410">
        <property type="protein sequence ID" value="ABX06410"/>
        <property type="gene ID" value="Haur_3774"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3774"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_13_2_0"/>
    <dbReference type="OMA" id="VALRLWF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3816-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14259" checksum="1F6EAF921C86400C" modified="2008-01-15" version="1">MDQQPKEQKRVITLSVGMIINLLLIGLVAGVAGGMFGIGGGAIMVPAMVLLLALDQKFATGTSIGAQILPVGLLGAFVYYKEGNLDWRASIIIALGLLVGTYFGAKIAAPISSATMKKFYGAFLFIIGARYLFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K2</accession>
    <name>A9B7K2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA_ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0323"/>
    <dbReference type="EnsemblBacteria" id="ABX02975">
        <property type="protein sequence ID" value="ABX02975"/>
        <property type="gene ID" value="Haur_0323"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0323"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1508619_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-326-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_ligase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19960" checksum="C2CF0FEFC6959EDF" modified="2008-01-15" version="1">MSDEFVAFPKIARLSRQVIVTEKIDGTNACIAIDEQGQIRAGSRSQWLTVEHDNYGFAVWVAANHNALLELGVGTHHGEWFGHRIGKRQYGLNERRFALFNTSRWNAENRPACCEVVPVLYDGVFDTAKIDAFLEDLRLNGSRMVAGFMQPEGVIIYHTAANIFFKKTMPNDGAKGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L3</accession>
    <name>A9B7L3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0334"/>
    <dbReference type="EnsemblBacteria" id="ABX02986">
        <property type="protein sequence ID" value="ABX02986"/>
        <property type="gene ID" value="Haur_0334"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0334"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047251_0_0_0"/>
    <dbReference type="OMA" id="MNNFPLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-337-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="30033" checksum="19127191A9E7D398" modified="2008-01-15" version="1">MQRTIGLCLGGGGGKGSAHIGVLHELERVGIQANMVAGTSIGAIIGAVVAAGYNATTIEQAFRATPLRRILSLDPASWGLIGSEKLAGVLSELLGDQLIEDLPIPYAAVAVDLVTGHEVVLQRGSLVEAALASAAVPGVFPPRRIEKYILADGGIRNNLPIDITRQLGAERVIAVNLIGEFDQFEVNNAAQSSLFSWRRWVPLTQLALAERAIGIMVHQITLQRLRETPPDLLFSPDVNRMSMADLLHLDDGIQAGIACVADYYEELQQWALWQRGEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M0</accession>
    <name>A9B7M0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0341"/>
    <dbReference type="EnsemblBacteria" id="ABX02993">
        <property type="protein sequence ID" value="ABX02993"/>
        <property type="gene ID" value="Haur_0341"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0341"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_3_0"/>
    <dbReference type="OMA" id="EQGDCAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-344-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="19"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="32742" checksum="5D3ACFDB462380E7" modified="2008-01-15" version="1">MNFPLLREFGSTGLQVSALGFGAGHIGGNELTEAEAAKLLHGLLDLGINLIDTARGYGLSEERIGRHLQQRRHEFVLSTKIGYGIEGYDDWTSPIITAGIDAALQRMHTDYLDIVHFHSCPVETLRAGEVIEALERAVQAGKVRVAAYSGDNAPLAWAVQSGHFGAIECSVNLADQRVISQVLPQTQQRQIGVIAKRPVANVAWRFAQRPVGDYAEVYWERLQAMQLDFDPERLLDIALRFTAYTPGVHSCIVGSRSLEHMQHNLALLQQGPLEPQLYAYLSSQFQTNDQGWVGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q3</accession>
    <name>A9B7Q3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1788"/>
    <dbReference type="EnsemblBacteria" id="ABX04431">
        <property type="protein sequence ID" value="ABX04431"/>
        <property type="gene ID" value="Haur_1788"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1788"/>
    <dbReference type="eggNOG" id="ENOG5033H98">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190652_0_0_0"/>
    <dbReference type="OMA" id="YENHHEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1816-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="63" mass="7125" checksum="209D696CC7A606A6" modified="2008-01-15" version="1">MRQQLEQRLATLKEEFQAGQTMLAELETKRENLNATLLRISGAIQVLEEELAREADQLAIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y8</accession>
    <name>A9B7Y8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3284"/>
    <dbReference type="EnsemblBacteria" id="ABX05921">
        <property type="protein sequence ID" value="ABX05921"/>
        <property type="gene ID" value="Haur_3284"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3284"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_7_2_0"/>
    <dbReference type="OMA" id="AHFMIID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3321-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="369" mass="39379" checksum="2C40BF193235F35C" modified="2008-01-15" version="1">MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNLNLPQNQPIVTVCGMGKMSLVAAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEIIQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQARGWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSHLFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQTEAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLEAGANRCAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B834</accession>
    <name>A9B834_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3331"/>
    <dbReference type="EnsemblBacteria" id="ABX05967">
        <property type="protein sequence ID" value="ABX05967"/>
        <property type="gene ID" value="Haur_3331"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3331"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3368-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="36590" checksum="1D43EEDB83998065" modified="2008-01-15" version="1">MALRIGINGFGRMGRLALRAGWNRPGFEWVHINELKGDAATAAHLLAFDSVHGRWNHGVSSQEQALMIEQQRLSYSNHSTIEATDWASHEVDLVLECSGKFRSPEQLAGYFAAGVKTVIVAAPVKQGALNIVMGVNDQLYDPQQHRLLTAASCTTNCLAPIVKVVHEQFGIKHGMITTIHDMTNTQNLIDAPHKDLRRARAASQSLIPTSTGSASAIGMIFPELAGRLDGVAIRVPLLNASLTDCVFELAQPTTSEAVNRALAEASRGALKDILGYEERPLVSVDYKGDPRSAIIDAALTTVTNQTQLKIMAWYDNEIGYVNRMLELAAKVAQLQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B866</accession>
    <name>A9B866_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3363"/>
    <dbReference type="EnsemblBacteria" id="ABX05999">
        <property type="protein sequence ID" value="ABX05999"/>
        <property type="gene ID" value="Haur_3363"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3363"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_2_0"/>
    <dbReference type="OMA" id="TSPLWGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3400-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="154"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33410" checksum="072C78BB530C40B1" modified="2008-01-15" version="1">MTLRQTGVLLILALVWGASFLFIRLGVETIPPITFVFLRLAIAAVLIYAVLRWQKVQLPRERKLWYSLGFVGFVNAALPYCLFAWGEHKMGTNASGLASIYNATTPLWTVILAFAFVRSERLTGVRTFGIVLGFAGVVYLFSRSIGNINSLDTWGQIACIIASSMYGIGTLYVRRNFGSLPALIPAFGQMASGAIMLLPVALVVDHNSWQMPSLVSLGSLFGLAILGTGIAQILYFWLVKQVGAARTAQVTYILPIFAIFWGWLFLNEAIRSDMLIGLCLILLGVIIVNGKWPFRRQTVAAPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B867</accession>
    <name>A9B867_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3364"/>
    <dbReference type="EnsemblBacteria" id="ABX06000">
        <property type="protein sequence ID" value="ABX06000"/>
        <property type="gene ID" value="Haur_3364"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3364"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_0_0"/>
    <dbReference type="OMA" id="CDYVYVT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3401-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="498" mass="55765" checksum="3171745536B83E53" modified="2008-01-15" version="1">MEFQLDRQHAKPLYIQLSEQLQERIRSGSLPAGTKLPPVRDLAESLGLTRLTVHNAYSELQASGWVEAYVGRGTFVAERIKPIIPAYEIRQRVVDELQTPWFSQGMLADMLRLAQQPNLISFAQAAPAEETFPVREIGRAIQQALRDPSALGYGPTQGELCLREAIATWLLDRNVVTSPDHVLVTTGAQQGVALALKAFVRQGDVVLVEEPTYLGFIEQATALGVRLIGIPLDDQGLRLDILQRVLCEYKPRLLYTVPTFHNPTGVCLSTERQEALLQLAQEHNLIILEDDVYGPLSYDAQAPHPIKARDTNGQVVYLGSFSKILTPGLRLGYLVARDEFLHPLLTAKRGNDLHCSPLLQRALADYLGRGQLAAHLRYVRELYRERRDAMERALNRYCPRDIQWTHPRGGLCYWLTLPSGLNGTDIYTEAIEAGVGVTLGNVFFPQPPRNAHLRLCFATQSPELIDRGIRILGDVLTRHVLRCGQLAARAWRETTPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J0</accession>
    <name>A9B8J0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5024</name>
        <name evidence="3" type="ordered locus">Haur_5252</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 4">
        <name>pHAU01</name>
    </geneLocation>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 4" key="3">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 4">pHAU01</plasmid>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5252"/>
    <dbReference type="EnsemblBacteria" id="ABX07654">
        <property type="protein sequence ID" value="ABX07654"/>
        <property type="gene ID" value="Haur_5024"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07879">
        <property type="protein sequence ID" value="ABX07879"/>
        <property type="gene ID" value="Haur_5252"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5024"/>
    <dbReference type="KEGG" id="hau:Haur_5252"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_471574_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5087-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="265"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="577" mass="67370" checksum="21CBC505705990A0" modified="2008-01-15" version="1">MPKRAAAPAWQQLQMQITCPKQYLYELIRPIVLTEESVADRASETAVPDHIITYHLDHFRTNGLPGLVAAPTPLQRAARFPEELVAFVLALKAEHPPLTAHELATICFIKHGRRPSIKTIRRVLAHHPLPQLTTRRFPPFHDNPDPIQRRHAILVLSLEGWTKKRIATYLQISRSTVYNTFARWHKEGFAGLQAKSRAPRRRHPKVTIAIQQRVRRLQRNHLLGAWRMHAALRREGIRLSPRTCGRIMAVNRDLCPELPKRQRSRKHEPRAMPFAAQYRHQYWTIDIRYLDMHRLGGGHIYCISIVENYSRAILSSAISRIQDTTAVLKVLYDAVAKYGCPDGIVSDSGSVFRSHRLQEVCQHLRIQQCPIEKRQPWQSYIETTFGIQRRMADEAEEGFRAAQSWDALWHAHRTWLLHYNTEVHWAHRQRQDGRETPAEVLTWIRGRPYPERLLQRIFAATRVKRRLDRVGFLRVRRWRIYSEIGLAKEAVEVWLEAQHVTITYADHHLRSYPATIDTDGWIRTMETGTRYEHPFGSRQLMLWDVIEDDWGKTQYVGSTPRRKSTIPLAEQLRFALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q8</accession>
    <name>A9B8Q8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07722">
        <property type="protein sequence ID" value="ABX07722"/>
        <property type="gene ID" value="Haur_5094"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5094"/>
    <dbReference type="HOGENOM" id="CLU_009583_2_0_0"/>
    <dbReference type="OMA" id="RICVITS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5156-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="199"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="42445" checksum="497989E76E4CA83F" modified="2008-01-15" version="1">MRIALVLSTPLPACEGIGFYVWNLGRFLTHHGHEVHIITRGEPTKPAYEQVQAIHIWRPAFWRIYPFHVDMHGYFVTQTLETIANTYGLDLIHVHTPLVKIPKSAYPVVVTVHTPMKTDTAAIPLRSVFDMLIKLQTPFSIRLEKRLFRQATTITTVATSVASELGAYGLQPHQVAVVGNGVDTATFYPPVDLQARFHQRYFLTVGRLAPRKGLEDLIASAAEVVKRYPTYRFFIVGQGPLAAVLQKQITQLHLDQHVQLLGHMADREQLADLYRGAWAYIHPAHYEGLPTALLEAMACGCPVVATAVSGALDVITPHNGVLVNPHAPVQLTQAVCRFIEQPQVARDLGQQAALTIQQQYGWTAIGQRYLATYHHAIQGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X2</accession>
    <name>A9B8X2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07786">
        <property type="protein sequence ID" value="ABX07786"/>
        <property type="gene ID" value="Haur_5158"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5158"/>
    <dbReference type="HOGENOM" id="CLU_420216_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5220-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="652" mass="69906" checksum="D6843AEF4DA07411" modified="2008-01-15" version="1">MELPALIAVLVDAILAQCPQYDRASVTVALESVFAGHPTLLGGNSISMLLGQNNDFTNATITIGDVHAGNQVHVTVQLPQPIDPLPAALAALASIPLKDVPAPRSDLPQASRLPFEASPHFVGRETELKALAQAIGTAQPAVVMPAVATGLGGIGKTSLVTEFAYRYGVYFHGGVFWLNCADPDQVASQIAACAVGLKLDTTGLSLDEQVQRVLNAWQSSMPRLLIFDNCEDPAILERWKPTVGGCRVLVTARSDQWPTLTQIRLGLLSSGESRDLLQRLCARLSDAEADAIAEDLGHLPLALHLAGSYLATYPHHTVEHYRTDLTIAHRSLKGRGALPSPTRHEQDVEATFMLSFKQLNPTDALDALALGMLDGAAWCALGVPIPRALILAFVPDGTDADDAVDALRRLQQLGLLDGVDAVVLHRLLAQVVHARLGSMDMLAVVEDTITTMASQINDSGIPTRMLPLAPHLRYVTMRALDRGDERTVRCAYTLGMFAYLRGAYGEAQPLFERALWLCEQRAEVSLVTVGLLNQMGLVLTHQGHYGEAQQCYERAVAIGAALMGDDHVHVHGIRLNLAQALHAQGQVQAAQALVADAAMSDRMDAATRAGSLNQRALLLEQQGQYPQAQALYEHAVALATSVFGAAHPTTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y4</accession>
    <name>A9B8Y4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07798">
        <property type="protein sequence ID" value="ABX07798"/>
        <property type="gene ID" value="Haur_5170"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5170"/>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5232-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1513" mass="164260" checksum="5A6804D050626CEB" modified="2008-01-15" version="1">MSDTGDKVDAYGIAQTPHHFIALTTGREYQLGLLRAVVAQLILKHNLTVSYFPEESYPAMKGEFARILDELSKHGIAETIYLDGLDQLQPEIDGSRDLSFLPPQPPPGIVIVLGSRPDETLKPLEILHRVDYDLPPLSEPDALALWRSVQPGMADGLFHDLYTALNGNALFVHLAADTMQGASVFDATSLIQQIEQNPSNLFGITLERIKRMPQSKWDVVWKPMLALLLVAQEPLRLDVLGDLLEHDHDTMQDAVWVLGGLVSQGIDQRVALHHLLFRDYLAVSVFNQREVKRWQQRLADWCAMDRDVIWTDHADMVEQSRRVYARHHYVTHLALAENWTVLWQVLDAGDYGEHKTRFDPSTRLYALDLDRGRESAINAGQSVDEHIQNLPRLWKYSLLRTSLASRVDQWPDDLFVVLAMLGRTQEALGHIELCSNPMRQIQLWENIIKWCDPKQQMIVITRMMQCAVGFSAFSQTCALATIARTLTTLGDVNDAIKILNEAIVITSTIDETENRANALIVIIQAAAALNHSEHSVKILDSVFCIVSSVYNLRNHTNILIALAETATTLGDLSRAFTIISTIHTVENRINALAVIARAAASLNNLQPAIRIFNDILSLASSIYPKRNCTNILVTITQTAVTLNQPDRIASFLDNALVIASTTQPTRDRTNILIVISHAAAILGHSNYTISVLDNALAIASTIYPTGNRADALSTIAKTTATLGNIDQALFITSTIDAVANHVDALSTIAKTTATLGNIDQALFIASTINTLANRADVLTSIAKTAALLDDFNYATKILNDTLVLLANVDTASRRVNALTAIAQTVASLGHFDQALAIASSIHTAGSRDTALAAIAQTAASLGHFDQALAIASSIHTAGSRDTALATIAQTAASLGHFDQALTIASSIHTAGSRNTALAAIAQTAASLGHFDQALTIASSINVAENRANTLATIAKTAASQGDLSLAVAIASTVDATRSRAKALATFAKPDASQGDHDHIRTPAIDATRNRSNTLISIAQTAATLGHFDQALAIISTINELWRYNKALVTIAQSAASLSYFDHAIAIASSIYVVEKRTHALATIAQTAALFGHFDQALTIVQSIDNSLDRAHALATIAQTAAKLGHFDQALTIVQSIDRGLWRQINALSEIAQTAAKLGYFDQALTIVSSIDSVEHRNSAFVAIAQTATSLGDFNRVLTMIIPTINNEQWRHTNALVSIAQTAASLGYFDQALAIASLIDVKRSSAHALATIAKTVASFGDFGRSLTITQSIDNDWYRADALATIAQTVASFGHFDQALTITYAIDSVENRNIALTTIAQTLISLGHFDQALPIVQSIDKSSHRNDTLATIAQRAASLGYFDQALTIVSTIDSVRNRNAVLTTIAQIAASLGYFDQALAAAAAIRDDIENHTNNLLTIAQRAASLGYFDQALAAASAIRDEDKRINILKGILQIVQPAKLLLPIIQKEWYTSKTSNKTWFCLPFLNSLFKNNLYLVGQILEGEEWVNAQLKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B970</accession>
    <name>A9B970_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5257"/>
    <dbReference type="EnsemblBacteria" id="ABX07884">
        <property type="protein sequence ID" value="ABX07884"/>
        <property type="gene ID" value="Haur_5257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5257"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_0"/>
    <dbReference type="OMA" id="SDQRHPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5319-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="446" mass="50927" checksum="63B24E130EBC0EE8" modified="2008-01-15" version="1">MSNDIRALPSLPQFPFLGNILSFRQDRLKFLRDLGSHGDLGVFYLGSYPVVFINSAEYAHGILVQHAQSVEKSLMLRKYMRPLLGNGLLTSENSFHRRQRKLVAPAFQHRHIANYANTISAYTDETQARWHQGQRIDIAQEMMRLTLRVMSQTLFSTDINTEADALGRALTTVLNYSNSVANTLIHIPYHWPIPQHKRVHAAIAQLDTTIQRLIHERRTQPTSTNDLLSVLLQAHDDDDGSFMTDTQVRDELMTLFLAGHETTANALTWTWYLLAHHPHIATKIKDEVDSTVGTRLPTMDDLSKLPYTLQVFKESLRLYPPVYMIARKASQAFELGSYHVPEGMAFVVSPYTIHRRADYFDHPEDFNPDRFDTSHEASIPKNAYIPFSLGPRNCIGNHFAMMEGHLMLAIIAQRMRLLLAPNQRIVPDPSITLRPKGAIHMIVERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B980</accession>
    <name>A9B980_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5267"/>
    <dbReference type="EnsemblBacteria" id="ABX07894">
        <property type="protein sequence ID" value="ABX07894"/>
        <property type="gene ID" value="Haur_5267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5267"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_420216_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5329-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="578"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="640" mass="68637" checksum="61361C3FEFF894FB" modified="2008-01-15" version="1">MDVPALIPIVADAILAHCPQYDRASVMMALESVFAGHPALLGDKTISMLFGQNNDFTNATVTIGDVHAGYTMNVHLPQPLDPTLAALIARASLPATIHHGDMTINESGVSGVVVRDNYGSIHQTIHQPQPIDPLPAALAALASMPLGYVPEPRADLPHPSRLPFEASPHFVGREEALKQLAQAIGSAQPAVVMPAVATGLGGIGKTSLVTEFAYRYGVYFYGGVFWLNCADPDQVASQIAACAVGLKLDTTGMALDEQVQRVLNVWKSPMPRLLIFDNCEDRVLLKRWKPTVGGCRVLVTSRSNQWPTLTQIQLGVLSPVESRALLQSLYSDLTDADADLIAEDLGHLPLALHLAGSYLHTYRPTITAYRAALSIAHESLHGYGAFDSPTEHEQNVDATFMLSFNQLDPDNTIDALALGMLDGAAWCAPGVPIPRELVLTFMPDETTHTARVDALRRLQQLGLLDGTDAVVLHRLLAQVVQAHLGSSETLAVVEDRIGAAASRANGTGVPRSMLPLAPHLRYATMRALDRGDAQAARLANSLGFYEDLRGAYAAAEELHERALAVREAVLGAEHPDTATSVNNLAVVLKRQGRYAEAQRLFERALAIREAVLGAEHPATATSVNNLAVVLEGGLSRSVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B988</accession>
    <name>A9B988_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-6 DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5275"/>
    <dbReference type="EnsemblBacteria" id="ABX07902">
        <property type="protein sequence ID" value="ABX07902"/>
        <property type="gene ID" value="Haur_5275"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5275"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_438549_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5337-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="89"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="623" mass="69485" checksum="71C0D3C936AE71F0" modified="2008-01-15" version="1">MADIAAGLNEIWKIFRAKGIVDDLLIIDHIATLLLEQNSLSPPSGLQGEPVLLPKVDEIKTRLSALSTLLEGGAAELFDRYILFRLDQTHLGGRYPTPRHLVKFMRTIAHVTANDSLLDLACGSGGMLAGRAQSAEHPTLTNGLEISPQWARLAWANCALHGLKDFTIEIADALTYPQAISVNRILMNPPFGTQVSTEGLSGRSETRLIEQAIKWLADNGRLCVLAPAGILFGGGREKELRKNLCTNQQINAIIALPKDTFQPFSTLQTYLLLITKSVPQAGTWFIRAERDGYMRGRGRDLTKQPTDASDFPLIESILGWDNTWNLTDDQQLLSYRQLTIDEERVLIIGAPAGSIFTQVERYSQGSKHIFLINVGLDAQRKSYIVDLNDPIPIKLMTQQREDIITEKFSKSKEEKPKLVTLLNGDHYSSAIAITTSGRLLGTRVLQDQIIKQADYTFKIDRYLPAEEMAVVNRPPSELLVEIRANQGRMAQYIDSLLRKLEAPQIGDGRLMAQVWQLEPTAIDVLSREQRQIWDSIKSLTLTVHSESASTGFETPNYFDVASLHQQQPNLPESELASMLELFEKLGLIVAVTLIDSQDQHLSAYRLLSERDIWRELPSSGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB3</accession>
    <name>A9AUB3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protoglobin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0381"/>
    <dbReference type="EnsemblBacteria" id="ABX03032">
        <property type="protein sequence ID" value="ABX03032"/>
        <property type="gene ID" value="Haur_0381"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0381"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127638_0_0_0"/>
    <dbReference type="OMA" id="VALAFYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-384-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protoglobin" evidence="1">
        <location>
            <begin position="15"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="19807" checksum="9741F0AD022FF120" modified="2008-01-15" version="1">MADRQSWSVKGTAILTELVKMMDVSAAESQLLGSLHDGAKAQTTAFTDAFYKRLLGHAATAEYLDGVSVERLTGMLGMWFSDLFRGNYDEAYAQQRLKIGEIHVRIGLPVRYPLAMLDVIMPFGEQVAATSSDPAKAITAFRKVLALDVALFNQAYEDNQLSHLADLVGGERLARLLLAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL7</accession>
    <name>A9AUL7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1901"/>
    <dbReference type="EnsemblBacteria" id="ABX04544">
        <property type="protein sequence ID" value="ABX04544"/>
        <property type="gene ID" value="Haur_1901"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1901"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="RCHLYRP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1930-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31535" checksum="DF388F2385B02A51" modified="2008-01-15" version="1">MSPNQSTPNSGQPLLKVEGVSKYFMRDKSRFAAVEDVSVTLNAGETLGIVGESGSGKSTLSRCIIRLYDPEKGRIFFDGIDFTGLSNKALRLKRRDIQMIFQDPLASLNPMMTVHSAIEDPMLIHNVGTARERTKRVHELLELVGLDVGAANAFPFEFSGGQQQRIGIARALALNPKLLICDEAVSALDVSIQAQILRLLQDLQKQLGLAYLFISHNLAVVEHMSDQIAVMYHGKVVEYDTVEEIFRAPKQEYTRNLIDSVPKIPRSDSLRFKRPRLNEDAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY4</accession>
    <name>A9AUY4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyphosphate--glucose phosphotransferase</fullName>
            <ecNumber evidence="1">2.7.1.63</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.63" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3938"/>
    <dbReference type="EnsemblBacteria" id="ABX06572">
        <property type="protein sequence ID" value="ABX06572"/>
        <property type="gene ID" value="Haur_3938"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3938"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065796_0_0_0"/>
    <dbReference type="OMA" id="HVEMLFS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3980-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047330">
        <property type="term" value="F:polyphosphate-glucose phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27219" checksum="32AEE9F96DA66755" modified="2008-01-15" version="1">MAILGIDIGGSGIKGALVDVAQGTMIGERLRISTPQPATPEAVAQTVQQLVQQLNWHGPIGCTFPAIVKNGYTLSAANVDQTWIGANADQLFEQATGCPFHMLNDADAAGLAEMKYGAGKEHNGVVMMLTFGTGIGSALFVQGLLVPNTELGHLEIRGKDAEHRASDRVREEKGWDWPKWAEKVNEVLARIEALFSPDLLIMGGGVSKRFDKFGQYLQTKAPLVPATLQNNAGIIGAALAASELFEQGHQIPNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH4</accession>
    <name>A9AVH4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2022"/>
    <dbReference type="EnsemblBacteria" id="ABX04665">
        <property type="protein sequence ID" value="ABX04665"/>
        <property type="gene ID" value="Haur_2022"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2022"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_322577_0_0_0"/>
    <dbReference type="OMA" id="THHIWRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2051-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="23"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="152"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="270"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="395"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="528"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="PSII_BNR" evidence="1">
        <location>
            <begin position="715"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="897" mass="96299" checksum="27FCC81DF63A67F5" modified="2008-01-15" version="1">MTDQQYVQDAVGWQLTPRSMNLQGVCLIDPQVGWAVGDGGLIVSTNNGGTSWQQHEVTEKDLRAVTFINRLHGWAVGRDGIIIATNDAGVSWQQQASGSEHNLYGVAFAPNASHGWAVGDDGIILTTQNGGETWQTQSSGLHQQLARCSTADGVHGWAVGHGGVILVTNDAGQTWQQQTSPTSNDLRSVFAVNQQVAWIVGRAGTVLITNDAGQTWNPVHTPSNKDFYGIVADASECAAWISGDDGSFYRTHDAGQTWQAQQSKTSKDLVALASSRDLLHGWAVGDDGIIISTNDHGNHWQIQLNGADQQLMALTFDQHGQTGWAVGHAGTIIHTTDYGRSWRTQTSGVAQPLWAVCSNPTGTIGWAVGSHGTILATTDAGKSWQQQRSPSSVNYYGMWFINQQVGWIVGAAGTVLSTHNAGRDWRQKLLGFGVADYYAISFSADGQAGWIVGAHGTILATNNAGQTWHQQPSACDAALLAIQIVNQQEVWICGSNGTLLQTIDAGNSWQQHACDPQQTFTDLVLIDQQIYLITQSGQCWSKLTTDQHWQTQTQLSRQALRWITHNSHAAITWIVGDGGTVLTSPDRGTTWTAQVSATGKNLYGIDFVPDGQIGWIVGDGGSLFSKQASATSLRVHSSPIIKNLYAIHSLGDGTKAWAVGREGSIIHTSDAGHSWIVQPNPCSSDLLAVYFADAQRGWAVGDHGTILATTDGGASWQQAPFATDQILWGLDFADAQHGWAVGDHGTILATTDGGASWQIQASGCDKNFAAIHCQPTSTHSWIAGDRGTILHSRDAGGSWQLQPTPTQKHLAAVHFLPDGQTGWAVGRSDTILMTRDAGNTWHQQSTTTGMSLWGVHGLSSSHYWVIGDEGTICATNDAGLSWQLQSRGFGKHYPQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU4</accession>
    <name>A9AVU4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4062"/>
    <dbReference type="EnsemblBacteria" id="ABX06694">
        <property type="protein sequence ID" value="ABX06694"/>
        <property type="gene ID" value="Haur_4062"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4062"/>
    <dbReference type="eggNOG" id="COG4636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076312_3_2_0"/>
    <dbReference type="OMA" id="PQAKSIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4105-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20032" checksum="D8605E9A69BFC6FB" modified="2008-01-15" version="1">MPTQRLIDLEHFLQADFQHAELVQGVVQPVSPVQLQHSLIVTKLLVSLSLWNQTQTQPGLVGTELGFILGPNTLRAADVFFINSNQLGQQQSGDRYWQGAPSLAVEVISPNERAIDVEEKINDYLAANLQLMWIIYPRLGSVHQIEPTQPRRILGLNDCLEHARILPQFVVPIRELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU8</accession>
    <name>A9AVU8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="12" type="ordered locus">Haur_4066</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4066"/>
    <dbReference type="EnsemblBacteria" id="ABX06698">
        <property type="protein sequence ID" value="ABX06698"/>
        <property type="gene ID" value="Haur_4066"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4066"/>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041018_2_1_0"/>
    <dbReference type="OMA" id="HMATISH"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="33611" checksum="A98FB97CF19CDFC5" modified="2008-01-15" version="1">MILLVVLSLAATAKLRSGNDEALKHPKGLQNALEYGVEVLYNTMQGVSPKYVARFFVVVATIFFLVLPSNWFGLVPGVGSLGVCFAESELEVMHGHTPVAGAGPSEKVIGAQKVWSDYTNKCAGTADTLVRAEASAQGIVLPATLETPEQIAQYKAVSAELDHAGKITPLFHPFLRPGSADLNMTLALALISFVVTEFWGFRKQGFGYLGKFFIFNQGPIQFFVGIIELVSEFARIISFTFRLFGNIFAGEVVLLVMAFLFPALLSLPFYGLELFVGLVQAFVFAMLTMAFIDMAAESHGDHGHEEHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV6</accession>
    <name>A9AVV6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent endonuclease of the OLD family-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0546"/>
    <dbReference type="EnsemblBacteria" id="ABX03194">
        <property type="protein sequence ID" value="ABX03194"/>
        <property type="gene ID" value="Haur_0546"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0546"/>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_389700_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-555-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="708" mass="80886" checksum="0D2200F2801D9A0C" modified="2008-01-15" version="1">MKITDVIIKNFRSIEHAQLNGCGDINVLIGKNNAGKSNILLAITTFFEFMERGKLFTFIEDSKDTINFFNNSEDSIIEISIKFNISQSDIDNLKIYKPENNTKNTYTKLSITIVNLLDKKSKVNAKILKNITLEGDKSNHELLDIINNNLSNLVQYHIILNYISSETLILNEIKEKNKSGFEQAISMLNNIIKSNNREHFNDIKKGAKNQELLDNLIEERIKSNNNDELSVIEGILNTTKHSNIDLEKLILSLKEIVQRISNHFHHIKERRPELDINDANVFLELKKKKASKATLQRIQTIANMVLGITIDAFVEDDNSDPVLDVDNFLIQVNGYGVKEALRIIFDYEIHRPKVVLIEEPELHLHPSLEMNLMRYLKEISAECQIFMTTHSTNFIDTGDVKNVYLVSKNESTTVRALNTEEAASLIPQELGLRLSSLFMYDKLIFVEGKLDEEILRTWTATLGVNLSQHNIGFVTMEGVFNQTYYAAEATLDFLSKKQIQTWFLIDRDERDQQQIDRIKQPLSGKSNVRVLNKREIENYLFVPRAIAQFLRDKGQISGLQATTEGITEEMIQQQITTCVETCKQQVIEKRIAARLPALRFDREVLFPKKPKAGDLVSRSIQELDRLTALLSDAKAQFPAIAQEEASAIEARWPTEKMNLVQGDVLLDAVFRVYGLRFNKSRDGAALAALMTDEEIDQEIKAFFKTITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW01</accession>
    <name>A9AW01_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0591"/>
    <dbReference type="EnsemblBacteria" id="ABX03239">
        <property type="protein sequence ID" value="ABX03239"/>
        <property type="gene ID" value="Haur_0591"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0591"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_1_0_0"/>
    <dbReference type="OMA" id="TACVEVT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-600-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="42"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="35856" checksum="A5F007CC34410F03" modified="2008-01-15" version="1">MTQEFVTQFWGVRGSHPSTGADFIKTGGNTSCVEMRVAGQQLIFDAGTGIVELGQQLVQQPNPRPILILLSHYHHDHIQGLPHFAPLYREDQMIYIVAPWNLYQDRVWELLASASSHSMLAERPGLLARRRTLLIEGGERLWWNADAATPLRVAADADELCPTGSVEIRSYHSLGHPRGGSMCYRVEHNAVSAIYATDIESYIGTDQRLANFARNSELIIHDAHYTPAEYANPKASRQGWGHSTWAMAIELAQAANIKHVALFHHEPAHTDSQIDQIEADAQAVYPLAFVAREGMQVDLLEQTSERSQGESISPVEPAIQPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW07</accession>
    <name>A9AW07_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0597"/>
    <dbReference type="MEROPS" id="C26.955"/>
    <dbReference type="EnsemblBacteria" id="ABX03245">
        <property type="protein sequence ID" value="ABX03245"/>
        <property type="gene ID" value="Haur_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0597"/>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_2_0"/>
    <dbReference type="OMA" id="TEHGHAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-606-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="21865" checksum="0282C88D7C743D93" modified="2008-01-15" version="1">MAVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAEAGISVPLIRELCMEYPILGVCLGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGVPSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHRTLPIEGVQFHPESIMTEHGKVLLANFLSIAKPELAEVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW91</accession>
    <name>A9AW91_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2101"/>
    <dbReference type="EnsemblBacteria" id="ABX04741">
        <property type="protein sequence ID" value="ABX04741"/>
        <property type="gene ID" value="Haur_2101"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2101"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_7_2_0"/>
    <dbReference type="OMA" id="YELSESC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2129-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734372" evidence="2">
        <location>
            <begin position="21"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="3">
        <location>
            <begin position="73"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="343" mass="36452" checksum="5651E04CE9F0C93C" modified="2008-01-15" version="1">MLKHCFAPMIGVLLIITACGTTLTTQTPDAVQPTNPSTSTATISTTTAPASAGYPVTIENCGRKLTFAKAPERIISLWQPPTEMLLALGLGDRIVAVGGNYDDYPANLQAEAATLKQIGTAMQWPVKEVTLAENPDFVISEQLEGFAFDSNSGYATVAELEAAGAQVYSNNACTMADAGSKRLEQVYTDLANLGAIFGVSERANAIITDLQSRQAAIEQRMVGVSPVNVLFYTGGEGPLNVLSGGVWGDLIVRAGGKNVFDQDVFQVSAEEFAAAQPDVILLGTFPGQDAAMLESYLKTTFPTIPAVQNNRLIPIPTINTEASIRIIDGLEQIARALHPEVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWB8</accession>
    <name>A9AWB8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2128"/>
    <dbReference type="EnsemblBacteria" id="ABX04768">
        <property type="protein sequence ID" value="ABX04768"/>
        <property type="gene ID" value="Haur_2128"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2128"/>
    <dbReference type="HOGENOM" id="CLU_1022211_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2156-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="30921" checksum="602B439079E88251" modified="2008-01-15" version="1">MTSFNLSCPECGAYFAANFPTCKFGGSANPNHSYVQADEYFSCTTCNEQLEISVRRDIQTGLISWISGTATAMSLHGWQCQRCHFSPSGQQLAIDCHGQLRVFERLEDLWIPSHSSPTKRYNLIGWLGEQLLLTDGAIWDLAQDRMLWQHYQPRILVKETAFDQQQQLVIRGVATSNSPYTQMLEAHHLDTGEQITAEIAALHNPNDHVICWNIEQNKGLCARGNQLELWHYDHTSHNFINIMSNKIKRGAIRQAWWLADGTILAVILVSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR1</accession>
    <name>A9AWR1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0664"/>
    <dbReference type="EnsemblBacteria" id="ABX03312">
        <property type="protein sequence ID" value="ABX03312"/>
        <property type="gene ID" value="Haur_0664"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0664"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_279755_0_0_0"/>
    <dbReference type="OMA" id="EASMEQE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-675-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="822"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1125" mass="121233" checksum="FB67D554B720911D" modified="2008-01-15" version="1">MAEETLELILSLRDEATSKLAAAGGQLASLSEQSTRAAATVQTLADKYRLAGQSQDLVAKSITDLTGKQAKLESTIEATTRALEQERAKADSNATTIATLERSLDKLQQQARSTSDAIERKVISIEKASVSMRQLEQRTLSAADAMRREDTAMTESKGSLGGLTDGLMGVAKAYVGVEAVRKVVQWGKEGAAIEGVEEAFDNLARKSGTSSTAYLAALKQASAGTISETNLMIGANKAVLLAGDRLAKDVPKLLEIARAASKATGEDINFMFDSLVTGLARNSKMIIDNLGITVDVAKANQDYAASLGKTVMALTDQEKALAFQQAVMQSGQQMINDVGVDVDSNAAKIARAEAHLQNFSNSLKVLAGNIVGFFAEGIDVLDRLTSQNFTLAQRLDEVDYKAIQSGKSFATYRQILTDLDATEGMVTEGQYHLAEAFLNTGMDAQAAMDRVRGLGDAFVRKAEAAGLSTTAIAELATRADTLSDKSERARGAVEATTFAFSAGSIDATLYQQALNEIEQQVVQDEIELTRLEGATLLVASATREATVSTDDFTAAVDVHTESLYAKIDATIEASMEQETLALLTQNARLAADDHIGALAAETSSLYDLAAAAQTAGDALAYKALMEGVAQLPRNTTASRNDLRAEGIDPRDQRQYKDAVADRAQDLVNPAGAAARQREAERQAGEFNRRNAERVRTARNPTRRSGGGSGSGSRGQSASQREAEQRIKQAEQTEAKIAKAKEDFQEKAERLTRDHYATVRKIEDDYHRKALAAEQSFNRQKFADQADFLESVASMHKDDRAEALRKQTEAWDKAQAMAQAGRAKEADAYLKAAEEEIEADQQRTDRMRQLRQQLADDTADLTAADRADLEEQLRLLDKADQIKDDLAAKRLSDLETANDSLKAERDEALASENADYSEAQAKLRDDFADTMRGILDKQTEQLQAHQTWADATIALYGLVASAASNAANAVGQAPSGTAAPGEDADFTIHNKVEASYALGTGDMGLTRDMVVQAHAREIIVDPTRSDGIRKAGGIDYLLKLSETERVNRSRADRLPTVTPTPLVQPAPRDYPPTVAAAGPTNVAIQAGGLTLAQIEALLRRILAQNNQGMGQQSQVRQRMKSTTLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU2</accession>
    <name>A9AWU2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRISPR-associated RAMP protein, Cmr6 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0695"/>
    <dbReference type="EnsemblBacteria" id="ABX03343">
        <property type="protein sequence ID" value="ABX03343"/>
        <property type="gene ID" value="Haur_0695"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0695"/>
    <dbReference type="eggNOG" id="COG1604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053305_1_1_0"/>
    <dbReference type="OMA" id="APINDWA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-707-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010172">
        <property type="entry name" value="CRISPR-assoc_prot_TM1791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39965">
        <property type="entry name" value="PTHR39965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01898">
        <property type="entry name" value="cas_TM1791_cmr6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="34772" checksum="7ED7299F2B840F3D" modified="2008-01-15" version="1">MRSSRLDIKYEHISTKDRPSDCNAGLWLDRYLPTQSKQLTNAEQSINSLPQHFADVTKIAHQMHSSKLYQQFFARWLNTLKEIPDICLLKAEVKGRMVVGLGAESVLENSIALQRTYGMPYIPGSALKGLASSFAHQRLGQSPANAAPINDWAKGGKFHRELFGTTELSGCVSFYDALYIPPDTPKPDGPLYSDVITVHHRDYYQGKKKVSSTDGQAQSKKQAFSNRNQEQSMPPADWDSPTIIPFLSATGHYLVALSGVEGWRDAARTLLANGLTHMGIGAKTSSGYGRMKLGEMCKNEQQIEALLQRLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ8</accession>
    <name>A9AWZ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2166"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04806">
        <property type="protein sequence ID" value="ABX04806"/>
        <property type="gene ID" value="Haur_2166"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2166"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_342195_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2194-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="828" mass="92726" checksum="7AC969D2E26F1A8D" modified="2008-01-15" version="1">MSKRQLNVVFWSGCGGETQRYRCQHAIEQLQYRGHKAQLFNQIDQAAIVAVAAADLVVVHRPKETHFWETIQQAAQGKPVVYETDDLLFDPALIDSMPIVAESTGFEQQFWRGYARGNPPVFARCDAAIVSTTPLAQAAEALQKPVWAHRNVLGDDWIAWCEAAYRERQTQAHVTIGYFSGTFSHDADLRLIAPALLKLLQQQPKLRLMLGGKITVPDILAPVANQIEQLPFVPLEQLPQLMSKADIILAPLDVDNAFTRCRSELKYLEAAALRLPVVASPIPAFAEAIRHGETGFLATSEAEWYSQLSNLLADATLRQRVGQAAYTHVLGHYTIATAAADYEAMLLAILQQFPTKPAQPALQPLLSQFQRDLTFHDRSVHMITGCDIGNAGNYRCRHRQEQLDWFDMYSGVTSLYNEPFKIADSIKFGILILHRVALDSNIATLIDAHQALGHPVIFDTDDLVFRTDLLHHIDAIKDWPADEVALYRDGVERYLKTMLLCDAVIVSTEPLAEQVRAFDLNAYVVRNALSQNQISYAEPIAAQRQAKPLAQPHDPVLIGYFSGTATHNRDFMQAEQAILHILATYTHVRLRIVGPLQLSKAFDPYIDRIERRELVPLEQLADEIAAVDFALAPLELDNPFCQSKSEVKYMEAALVGVPLIATPIEAFRYAITHGINGMLAANEQEWIEALEALVTDPSLRQRLGHEALADAHARYSPKARSRELHNVLQQIWSMYTRQMSLIKSNAMLLGANKSLSKGNEVLVMHIDGLITSNQALHYRVQELERDNAQAKAYAHQLEIQLQQIANGIFMQFSGKAKGLLHRLINRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC3</accession>
    <name>A9AXC3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4211"/>
    <dbReference type="EnsemblBacteria" id="ABX06843">
        <property type="protein sequence ID" value="ABX06843"/>
        <property type="gene ID" value="Haur_4211"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4211"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031866_2_0_0"/>
    <dbReference type="OMA" id="LMKGTRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4258-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="45"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="415" mass="44488" checksum="51EDB835CC815F5B" modified="2008-01-15" version="1">MTEPVALSAVWSREPLPSGTSQVNYVLIQAKPHHVPTVQAAPPLNFCLVLDRSGSMAGDKIQHLREAVREIVANLRPIDAVSIVLFDDTLEVLVPARLADDLPALQNAIESIGEQGGTAMSLGLQAGLAELQKFQAADRVGRVLLLTDGQTWGDEDTCRDLAKQIGDLGVSITALGLGTEWNEALLDDLATASNGESDYIADPSQISKYFQQTLQSAQTTTVVNARLLLRLLPGVTPRAVYRVQPTIANLGYKPIGEREVTVSIGEIAGDGASVLVDVMLPEREAGTFRIAQAELQYDAPVLGIKEGKIKIDIPLSFNVDPKASVVNPPIMNTVEKVTAFKLQTRALSEAEAGNIGSATQKLRAAATRLLDLGETELAQTMEQSAQQLEAGGQIAAADQKALRYATRKLTQKLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE3</accession>
    <name>A9AXE3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4231"/>
    <dbReference type="EnsemblBacteria" id="ABX06863">
        <property type="protein sequence ID" value="ABX06863"/>
        <property type="gene ID" value="Haur_4231"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4231"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="NVFQQCV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4278-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33748" checksum="741F5A3381464925" modified="2008-01-15" version="1">MTAIQVENLVKIYGSLRAVDGISFEVAKGEVFGMLGPNGAGKSTTTEMIEGLRKPDAGNIHVLGHDVLKNIEPIKQRIGIQLQTTSLFQKLTTRELVKLFASFFKNTLPIDEVIGLVNLEEKVNTASKDLSGGQRQRLAVAIALINDPDIIFLDEPTTGLDPQARRSMWDVVSNLQKRGKTVFLTTHYMEEAERLCDRVAVVDHGKIIALGKPQTLIHDNFHETALEFSDDERLPEQLLTSLPAVERVQNEDGITTLYSTGVARTTNALMALVEQQQTELRGFTIRAATLEDVFLKLTGRRIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP6</accession>
    <name>A9AXP6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0812"/>
    <dbReference type="EnsemblBacteria" id="ABX03460">
        <property type="protein sequence ID" value="ABX03460"/>
        <property type="gene ID" value="Haur_0812"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0812"/>
    <dbReference type="eggNOG" id="COG1690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_1_0_0"/>
    <dbReference type="OMA" id="QTRGVEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-825-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="270"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="391" mass="42397" checksum="7A02DFBFAFB1DB7E" modified="2008-01-15" version="1">MQYVENIPIWGDPIDQGALSQIKTCALEADAVALMADHHKGYAVPIGGVVAYRDAISPSGVGYDIACGNKAVLLDLPASEVRAKIKPIMDDIWRSLSFGVGLNNRQSVDHDLFDDPAWQVPAVKSLKQTARNQLGTIGSGNHYVDLFADELDRTWIGVHFGSRGLGHKTATYFLEAGGAKDGMDVAPLILPTASDLGEQYLSCMALAGRYAYAGRDWVCAEVARILGATILEEVHNHHNFAWRETHNGVDLWVVRKGATPAFPGQRGFVGGSMGDISVILEGVDSPEAQTALHSTVHGAGRVMSRTAARGKINYRTGKVIAPGKISREMMNEWIQQQGVELRGAGTDESPHCYKRLPEVLNHHANTIKIVHTLQPLGVAMAGENEFDPYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ4</accession>
    <name>A9AXQ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0820"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03468">
        <property type="protein sequence ID" value="ABX03468"/>
        <property type="gene ID" value="Haur_0820"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0820"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023845_4_0_0"/>
    <dbReference type="OMA" id="TEAKAWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-834-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="34245" checksum="56F67A24885792E9" modified="2008-01-15" version="1">MIPGQISIIIVSYNSAALLPACFASLAMTNDDNYQLIVVDNASSDGSAELVRQQYPHVQLIANQHNQGFGAACNQGMAAATGEYFLLFNPDVQITPNWLTLLRQHLATNPQAAIICPTTLYPNQALPTRQGVAITAAVPGCAMLLRRSAWQAIGGFDPAIFLYWEDTELCWRAWLLGWQVLEDFEALVVHERGGSGGGQRWLVESSKNGLYCYLKLRPWSAVLGYSLRMLAKTAIVSLRQRNLAMLNIWLWHGRNLKQTLATRRAIQAQITADRSEVEGLIKQHLARGKQERRASQKSKVKSQKAETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT8</accession>
    <name>A9AXT8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative alpha-methylacyl-CoA racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2264"/>
    <dbReference type="EnsemblBacteria" id="ABX04904">
        <property type="protein sequence ID" value="ABX04904"/>
        <property type="gene ID" value="Haur_2264"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2264"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_4_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2292-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="12723" checksum="FDEE72967CDB625B" modified="2008-01-15" version="1">MLPLTGITVVALEQAVAAPFATRQLADLGARVIKIERPEAGDFARHYDQAVHGLSSHFVWLNRGKESLTLDLKQPQAQVIMHQLLATADVFIQNLAPQASQRLGFGAETLRRANPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY44</accession>
    <name>A9AY44_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4294"/>
    <dbReference type="EnsemblBacteria" id="ABX06926">
        <property type="protein sequence ID" value="ABX06926"/>
        <property type="gene ID" value="Haur_4294"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4294"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430714_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4346-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734418" evidence="1">
        <location>
            <begin position="23"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="653" mass="72172" checksum="C3D6999564216339" modified="2008-01-15" version="1">MKRWMLLFLVVVSLALPQASSAAEQQCFEQTGFCIEGRFLQYWQKNGGLQVFGYPLGIAQDVYNQDSQQSFLTQQFERARFELHPEFAAPYDVLIGRLGDDLLRYRNIDSSMLPLETGSKAGCLWFETTGHNVCNQANGIGFMSYWQNHGLNDPKLDNFGRSLQLFGYPLTEPAMETNANGDRVLTQHFERARFEWHPNQPDQFKVLLGLVGKESQKLVYGEGSNPSHLTQLDSRVFFTANDGVHGQELWVSDGSNQGTRLVKDISPTGSANPYKLTAAAGQLFFVVSAGNSEQLWVTNGTEAGTTMVYSLSRPAADEPAIVDLAPVASGVIVMGYTTEFGIEPWFSNGSNAGTALIRDINPGAAGSEIKVSTCCSYYFATEFTPMGSSLAFMAKTGNAGNQIWLSDGTTQNTRQISTFEQNNELVTELERLNNDQIIAAVQQPDMVQIVKIELATGKHSQLTSHGRFHVGTRLIVSAYDLTNVAGKVYYSVSNSDQRTNLWQIEAKTGTSANQVDLAGYQIKRLITNPIYSQMYQQLRNSDGSEAGVWAWDGTNLQQRSSLDFQQLAYNGQHLFGLIGTNSPYRLYANAATNQNLGYIGSGMHHLGNSPSFAQVNRFSSNQGIFLALPDLAHGLELWYSDGNTLRMVKDIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ48</accession>
    <name>A9AZ48_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purD</name>
        <name evidence="10" type="ordered locus">Haur_0946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0946"/>
    <dbReference type="EnsemblBacteria" id="ABX03594">
        <property type="protein sequence ID" value="ABX03594"/>
        <property type="gene ID" value="Haur_0946"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0946"/>
    <dbReference type="eggNOG" id="COG0151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027420_3_1_0"/>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="107"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="43391" checksum="6F090C108ECE3F37" modified="2008-01-15" version="1">MRVLLVGAGGREHALAWKIAQSPLCEHLWIVPGNPGTATLGTNVDLAADDAAGIVGLATREQIDLVVVGPEAPLVAGLGEVCEAVDLAMFGPSSEAAQLEGSKAFAKMIMLEAGVPTAAAHTFDNSAAAIAFVEADQQAWVVKADGLAAGKGVIVPEDGDVAATISAIRELAATNAGTRLVLEEKLTGPEVSLLALCDGERAIPLIAAQDHKRIGDNDTGGNTGGMGSYAPAPILPYAEAQALVDVIFTPVLRTMAARQIPYRGVLYAGLMLTPNGVKVIEFNARFGDPETQALLPLLKSDLLELLHKVATSNLADVTIEWHDGAAVCVVLSAAGYPAKPRTGDVITGLDRLPSDVLAFQAGTATNAQGELVTAGGRVLGITAVAPTLREARDKAYAATELVEFAGKYQRSDIAARGLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ80</accession>
    <name>A9AZ80_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0978"/>
    <dbReference type="EnsemblBacteria" id="ABX03626">
        <property type="protein sequence ID" value="ABX03626"/>
        <property type="gene ID" value="Haur_0978"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0978"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101141_2_3_0"/>
    <dbReference type="OMA" id="DMDAMGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-992-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="15089" checksum="1C3A52A6B35B8434" modified="2008-01-15" version="1">MSFQYPLEVRFRDLDGLGHVNNAVYLTYFETLRLHFALELLGVAHLAEVPFILGEISVRFLKPVFFGDQLQGSVDVSRIGHKSFTMIYTIKRGNEIVTQGSTELIWFDYKTQRSVPIPDSFRQQVASYQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZG4</accession>
    <name>A9AZG4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2470"/>
    <dbReference type="EnsemblBacteria" id="ABX05108">
        <property type="protein sequence ID" value="ABX05108"/>
        <property type="gene ID" value="Haur_2470"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2470"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_4_0"/>
    <dbReference type="OMA" id="WLTEPAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2498-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="24310" checksum="A522FA2B232FD64B" modified="2008-01-15" version="1">MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANNTARAIAEFHPEVPFIDEPALLEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGESFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVADALGINMDRINRLWITNASISVIEYGEDLPYLVSLSEACHLGKLATVRENQTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ6</accession>
    <name>A9AZJ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2502"/>
    <dbReference type="EnsemblBacteria" id="ABX05140">
        <property type="protein sequence ID" value="ABX05140"/>
        <property type="gene ID" value="Haur_2502"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2502"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030705_1_2_0"/>
    <dbReference type="OMA" id="GWCQGRM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2530-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017224">
        <property type="entry name" value="Opine_Oxase_asu/HCN_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037495">
        <property type="entry name" value="Opine_OX_OoxA/HcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="43894" checksum="BDE2F8EFA952EE3B" modified="2008-01-15" version="1">MSLNVVIVGAGPAGLAAAWSASQSNANITLIDQAAQAGGQIWRGGQGYAPKRYRHLFGQQTTLHYRKQTHVLGASEQQLYLATPQGPQQLRYDRLILANGARELFLPFPGWTLPKVVGVGGLQALVKGSLPIAGKRVVIAGSGPLLIAVASQLKQRGAIIKAVVEQVPIAQLLRFGRSLVGNPTKMLQAAQFAQALANTPFYVNTWITAAEGEGEVQQVQLNNGQRIECDYLACSWGLIANTELAQQLGCRLEQNFVVVDRSQHTSRDQVYAVGELTGIGGEDKAVIEGQIAGFVATGNYQAASQLAQQQAQARQFSQQLAASFALRPELRQLAQANTIVCRCEDVTLAQLQSQPSWRSAKLQTRCGMGICQGRVCGGATQYLFGWSQDSVRFPIHSVSVADLVMESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL1</accession>
    <name>A9AZL1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2517"/>
    <dbReference type="EnsemblBacteria" id="ABX05155">
        <property type="protein sequence ID" value="ABX05155"/>
        <property type="gene ID" value="Haur_2517"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2517"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_2_0"/>
    <dbReference type="OMA" id="YHEKTIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2545-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="120"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="28798" checksum="D670503AB25A8DD1" modified="2008-01-15" version="1">MELEQTVLPDIVKEIRQLRSRDARDRTGTYYIEGARIVAQAINAGLPLEIGAISLELLSRTEHSAGTVSALRKAAKQMVELSASAFAGISFKENLQGIGAVVKLQQEPLSNVQLTDRPWVALNGVGNPGNLGAIMRTCDAVGCEGLILIGDTTDPYHPAAIRASMGSLFALRMVRTTFDEFAAWKQTNGYHVIGTTPDVEQEYQTISYPSPAILLMGSERLGLSVGEQSVCDTLVRIPMAGTCDSLNLGVATSIVLYEMFRQQRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZT2</accession>
    <name>A9AZT2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PT repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4504"/>
    <dbReference type="EnsemblBacteria" id="ABX07136">
        <property type="protein sequence ID" value="ABX07136"/>
        <property type="gene ID" value="Haur_4504"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4504"/>
    <dbReference type="eggNOG" id="COG5624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_599608_0_0_0"/>
    <dbReference type="OMA" id="PVHEHTT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4559-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="456" mass="47718" checksum="7E3A9FF5AB953024" modified="2008-01-15" version="1">MNPKLQRWITQVILLVTIVVAGGVSTTFANVGQAIDSAAVDTVVEPTAEPSVEPTAEPTTEPTAEPTATDLPSTPIPTVTPVCNPQIDLSGWFSTNSLGKIQNKSTTCVYTVGMASYQKVDEIIDHQVIYSWETGRIEPNQILALNVAVPECAAQIDLFYGPVLHSLDGQRYGERLITARHTGGINYCGLAAPTSTVEPTAEPTATSTLAPTAEPTATSTVEPTAEPTATSTLAPTATNTPTAEPTATNTPAPTATNTPTAEPTATHTPAPTATNLPTSTATRTPTATPTTPPTRTPTAIPSPTSTKTPTPTATIRPTSTPTRTPAPTATNTPTGANCTYTDGYWKTHPREWPLGSMMLGGVQYSQNQLMAIFIMNVRDDMSYTLAHQLIAAKLNVAQGADGSQINGTIAAADMWLEQNPLGSKPTGFIATTGTGYSSTLNSFNSGLLGPVHCNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZT5</accession>
    <name>A9AZT5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Threonine synthase</fullName>
            <ecNumber evidence="6 10">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_4507</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="6 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4507"/>
    <dbReference type="EnsemblBacteria" id="ABX07139">
        <property type="protein sequence ID" value="ABX07139"/>
        <property type="gene ID" value="Haur_4507"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4507"/>
    <dbReference type="eggNOG" id="COG0498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_0_0_0"/>
    <dbReference type="OMA" id="MWGFQAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4562-MON"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 10 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="30"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="11">
        <location>
            <begin position="194"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX07139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="37738" checksum="E287B368198EAD0F" modified="2008-01-15" version="1">MSQLTTHASAVPLLERYRQFLPITAQTPIVTLHEGNTPLINVPRLAAHLGVRELWLKLESMNPTGSFKDRGMVMAIAKALEAGSKAVVCASTGNTSAAAAAYAARMGMECVVVVPAGKIALGKLAQALMYGAKLLVIEGNFDQALDMVRVLAEQHPITLVNSVNPYRLEGQATAAYEICDVLGDAPDYLALPVGNAGNISAYWMGFKRYYEAHRSESLPKILGFEATGSAAIVRGEPIAYPETVATAIRIGNPASWQLAVNARDESEGTIDHVSDEEILAAWRDLSALEGIFCEPASAAGVAGIRKLLAAGSIDPNGRFVAVLTGHGLKDPQLAVEQFSVPQAIPAELSAVVAALDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZZ2</accession>
    <name>COBQ_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cobQ</name>
        <name type="ordered locus">Haur_1051</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZZ2"/>
    <dbReference type="STRING" id="316274.Haur_1051"/>
    <dbReference type="EnsemblBacteria" id="ABX03699">
        <property type="protein sequence ID" value="ABX03699"/>
        <property type="gene ID" value="Haur_1051"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1051"/>
    <dbReference type="eggNOG" id="COG1492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019250_2_2_0"/>
    <dbReference type="OMA" id="EIHHGVA"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000090229" description="Cobyric acid synthase">
        <location>
            <begin position="1"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="GATase cobBQ-type" evidence="1">
        <location>
            <begin position="252"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <sequence length="489" mass="53562" checksum="8F6743D4EC36D79F" modified="2008-01-15" version="1">MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSIAVQAAAAKLTPSVQMNPILIKPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSLDQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQTLLVGDIDVGGIFAAMLGTLMLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVALERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGTKHTLAARQWLTEQGFDQAIQQFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLPITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTELLADQPAFSIQQAESTHADGCMRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLTKLLGQEIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZZ5</accession>
    <name>A9AZZ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1054"/>
    <dbReference type="EnsemblBacteria" id="ABX03702">
        <property type="protein sequence ID" value="ABX03702"/>
        <property type="gene ID" value="Haur_1054"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1054"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="SHQVELM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1071-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="30077" checksum="C7AFE300207D3A0F" modified="2008-01-15" version="1">MSNPILTIKQLGCRYGSRTVFEQLDLQATKGEVLALLGPNGAGKSTLLRCLARLQRPQQGQIWLDGQPLWHIKPRLVAQQIAFAPQQAGLNPELTVEQMLLLGRTPHRGWLLPMTKADRAIVEELLERFNLAKYRRQSLAELSGGEQRRVIIARALAQQPKMLLLDEPTAHLDLKYQLEIMQLVSDLAHNDGVCVILTLHDLNQASLCADRIALLAHGRLQAVGAPSAVLRSELIEAAYEVPIQMIEHPNHNLPLVMLQPQRKEVAWPN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A2</accession>
    <name>METE_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">metE</name>
        <name type="ordered locus">Haur_2573</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21196"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58140"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
            <dbReference type="EC" id="2.1.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B0A2"/>
    <dbReference type="SMR" id="A9B0A2"/>
    <dbReference type="STRING" id="316274.Haur_2573"/>
    <dbReference type="PRIDE" id="A9B0A2"/>
    <dbReference type="EnsemblBacteria" id="ABX05211">
        <property type="protein sequence ID" value="ABX05211"/>
        <property type="gene ID" value="Haur_2573"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2573"/>
    <dbReference type="eggNOG" id="COG0620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013175_0_0_0"/>
    <dbReference type="OMA" id="KVMKGML"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000097830" description="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase">
        <location>
            <begin position="1"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="687"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="428"/>
            <end position="430"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="428"/>
            <end position="430"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="509"/>
            <end position="510"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="635"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="637"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="659"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="719"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00172"/>
        </source>
    </evidence>
    <sequence length="748" mass="82813" checksum="B4DF9D38897AC830" modified="2008-01-15" version="1">MNFQTTVVGYPRVGVGRPYKQALERFWSGKLDETGFRAAINELCHDRLATQAQRLDLVPVGDFSLYDHVLDTALMLGAVPARFGKVDAHNLQGYFALARGRDGLPALEMTKWFDTNYHYLVPEIPERWELQANLVLEQVRFAQNVVGAKARPVLLGPWTFLRLARLAGAELAQHLQQLTAMYAQIVRELNDCNVAFIQCDEPALVGDVTEEEWQAFAACYRELSKHGKIVVQTYYGDVTPWYRELCRLPIHGLGLDLVQGHANWAAIQYHGFPQDKILVAGVVNGRNVWRSDLADLYTKITGLSEFVAPERLILSSSCSLLHLPETVTAERNLPVAVSSGLAFAQERLAELELLANALRDGIASVQPTWDAALASRQQWLDGVGRIVPAVRERTAALGTETPARLAYAERVPLQQAKLNLPLLPTTTIGSFPQTAALRKARAEAKRNPTGYAETINAEIAHVIALQEQWGIDVLVHGEPERNDMVQFFAEHLAGYVATQEGWVQSYGSRCVRPPVIAGDVYRTAALSVAETAYAQSLTKRPVKGMLTGPVTMLQWSFVRDDLPRSAVAAQIGLALRDEVTDLEAAGINIIQIDEPAFREGLPLRRNDWQNYLDWAVRAFRIATSDAKPSTQIHTHMCYSDFNDIIAAIAALDADVISIEDARSAGSLLAGLEGRYTQQIGPGVYDIHSPNIPTVEQLVARMRQLLNYLPAEQLWINPDCGLKTRTYAEVAAALQAMVTATKQVRNQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F9</accession>
    <name>A9B0F9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4546"/>
    <dbReference type="EnsemblBacteria" id="ABX07177">
        <property type="protein sequence ID" value="ABX07177"/>
        <property type="gene ID" value="Haur_4546"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4546"/>
    <dbReference type="eggNOG" id="COG0758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029601_1_1_0"/>
    <dbReference type="OMA" id="SEMPFGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4601-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="301"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="369" mass="39574" checksum="C2030557AF3A127B" modified="2008-01-15" version="1">MDERHAYIAFNLTPGIGPQRLQALIKHCGSAAAAWSATLDDWRAAGLDRRSIQALQHAQQHLDLEAELRTIAEQNIKVVLQTDSDFPAMLHTIDPVPPLLYLRGSLIETDRWAVAIVGTRNPTPYGREVTYKFAGELARAGLTVVSGLALGIDAIAHRTALDNNGRTLAVLGSGLQQIYPSQHRQLAADVSQQGALLSEYAPTTEPLSGNFPARNRLISGLSLATIVVEAGERSGALITARFALEQGRDVFAVPGSILSHSSDGPNQLIVDGATPLRSVEQLLEQLNLHQAQAQQTVSTIVPETPAEALLLPHLSGQPTHIDELGRSCGLAAHDLAATLGLMELKGMVRHVGGMHYVLARETPAPYDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0M3</accession>
    <name>A9B0M3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4610"/>
    <dbReference type="EnsemblBacteria" id="ABX07241">
        <property type="protein sequence ID" value="ABX07241"/>
        <property type="gene ID" value="Haur_4610"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4610"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_0"/>
    <dbReference type="OMA" id="EWDETHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4667-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="122"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="41235" checksum="8D23D64529201373" modified="2008-01-15" version="1">MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYGGAGLDYVSYAIMIEELSRVDASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKLGAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNGSKADTILLMTMTAPEKGVKGITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILNGGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTYHAAWLKDQGENYIAAAAMAKVYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITEIYEGTSEIQRLVISREIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0R2</accession>
    <name>A9B0R2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">Haur_1134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1134"/>
    <dbReference type="EnsemblBacteria" id="ABX03782">
        <property type="protein sequence ID" value="ABX03782"/>
        <property type="gene ID" value="Haur_1134"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1134"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_0_1_0"/>
    <dbReference type="OMA" id="RGAESCY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="13"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27144" checksum="4B794E2F3588A62B" modified="2008-01-15" version="1">MAIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKGHGGFPASTCISVNDVVCHGIPDKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQSAKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGFSVVREYTGHGIGRKMHETPPDVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAITTGDPEILTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S0</accession>
    <name>A9B0S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1142</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1142"/>
    <dbReference type="EnsemblBacteria" id="ABX03790">
        <property type="protein sequence ID" value="ABX03790"/>
        <property type="gene ID" value="Haur_1142"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1142"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_71_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1163-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="259"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="333"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="404"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="631" mass="71844" checksum="7D91FBCAD8475F2B" modified="2008-01-15" version="1">MPRKLKWPLAGAWQRRLIKATRRKDVTLEQFPVGLVWFQGSQVFFNQAVTAMIGYSNAEIATTEQWFSTLYGPEAASMRQLYATTSAATLGQTIHGFVVNRQNQSCLLECTLASHGHRQVWLVRDITESNRLERLLLQTEQTARVGGWEIDLRTNQVFWTREMYHILDTTAHEYTPTIENQNFFHTNATLIQLEAIFRQMIEQRGSFDMSVEMRTFRGRSFWGRFTGRVELEFGQPIKIYGSLQDVTEHHQLTEALRVAEHDYRTIFETTKIGIFRITPDGRVLRANPALVRLAGFAHEHELVDYVADLTTMYVEPQRFEYLRELLQTNGSYDEIESEVYRPATGERIWISETSRLVYAEDGSMLYAEGTIQEITARKQVEEALRHARDAAEAANHAKSTFLANMSHELRTPLNAIIGYSELLMDDTDFDDPTMVEQFRHDIAQINDAGHQLLNLVNDVLDLAKVEAGKYQVAAETFDLNSLVRDLIATINPMAQKNANSLYFEPNKHLPLIHTDRSMLRQILLNLLSNAAKFTKAGSINISVSFDPASQHVQCRVRDTGIGMNDEQMQRLFEPFTQGDASTTRRYGGTGLGLALCRHFIELLNGSIQVESVFGQGSIFTIVFPCLVEAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S3</accession>
    <name>A9B0S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1145"/>
    <dbReference type="EnsemblBacteria" id="ABX03793">
        <property type="protein sequence ID" value="ABX03793"/>
        <property type="gene ID" value="Haur_1145"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1145"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="HRREYGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1166-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="530"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="736" mass="81632" checksum="A464B4C0DF1E0C73" modified="2008-01-15" version="1">MQTEHSDLLPRYTTALIGRDAETAEIGALLAQGQRLISLVGASGAGKTRLAVDCARLYADQFVGGCFFVSLVPIRAAGLVLATIAESLGIAPTSDQPLLTTIAAHFPHQPSLLILDNIDHVVEAASDVQALVTAVPQLTILVTSQVALNVAAETIYRVPLLSVPAEDARLSASEILQYGAVQLFSERLRRLQPMLKVDQPQAQAIAEICRLVQGLPLAVELVASHSRSLPPSDLVRMVRHHLRLGAAMIDKNSTMQRKEILWPVLDWCYRLLSPTLQVLFIRLGIFRGSWTLESAEAICAGIPDVPINVVEGLQTLVDKSLVQLETLPNGDHRYLMLDAVHAYAEGRLQRRREANHLQRLYSSYFTHLAESAEKPLLGADQPLWMARLQSDIYNLRSVLDWAVEQHPATALRIAGSLWLFWFTKGYAQEARVWIRQAWRREHEIEPVVRAKAAIAAGICAQYFADHADATLWYERGQALFKQVGDTFGETRALHNLSSLAYQQRYYQKAVELGEDVVARWQAMDDRSGEAAALSNLASSYTGLGRFDDAERCYQQSLQINRSLGNQVGIILCQSARGWLACAIDDLELAQEALEESLNLALQNDARNLIPGSQSALARVWYKKGQIQRAFELLRPVFDIQAQLQNLEQSGEEMITLAAILAEHYPKLAQQALEFAERMQDPYNQELQPDPATLLFFKQTAEQVSHFVGQAAATSTLPTISEFLDSVDQTVDPRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B126</accession>
    <name>A9B126_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2666"/>
    <dbReference type="EnsemblBacteria" id="ABX05304">
        <property type="protein sequence ID" value="ABX05304"/>
        <property type="gene ID" value="Haur_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2666"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1353095_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2696-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PAP2_3" evidence="5">
        <location>
            <begin position="60"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="22407" checksum="F96F22E8E9AA9C17" modified="2008-01-15" version="1">MVGLQQQSTSSQPSADFALALCSFVGYFAASHVPDQPAYVVPATALDRAIPLMPTSVLPYLSLYPFLGLNAAYFWPKPTHARRVFQAITLLNSLGSIVFCSVRTTVPRPQSTTSRLLKWLWRVDPPYNAFPSLHTAYALILAEAHWRVRSPWRWLVSAWAMAIIISTLTTKQHHLWDVLGGIGLARLVAGKLFADLSPAHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I4</accession>
    <name>A9B1I4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1221"/>
    <dbReference type="EnsemblBacteria" id="ABX03869">
        <property type="protein sequence ID" value="ABX03869"/>
        <property type="gene ID" value="Haur_1221"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1221"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_0_1_0"/>
    <dbReference type="OMA" id="EWMDCGN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1243-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="35874" checksum="CDCB889D3CF878D3" modified="2008-01-15" version="1">MNVIIPTAGLGTRLRPHTHTRPKPLVPVAGKAVIGHLLDKLKVLPLDDVVFITGYLGTQIEEYVRKNYNFKSHFVEQTELKGQAHAIALAREMVSGPTLILFVDTIFEANLNVLNQTDADGVIYVSEVEDPSRFGVALLEDGIITKLVEKPSTPVSNLALIGAYYVREVKELFAAIDVLIEQNIQTKGEFYLADALQLMISNGTRFSAETATMWEDCGTAPALLRTNRYLLQHETGNVEQRDGAIIVPPVFIGENVEIRNSIIGPYVSVADHSVIVDSIVRDSIINQGASIQSSTLEGSLIGEGAHIKGEFQHLNVGDSSVITFGSTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I7</accession>
    <name>A9B1I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1224"/>
    <dbReference type="EnsemblBacteria" id="ABX03872">
        <property type="protein sequence ID" value="ABX03872"/>
        <property type="gene ID" value="Haur_1224"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1224"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_0"/>
    <dbReference type="OMA" id="WRHAFPT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1246-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="120"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36581" checksum="D63F1F9088120E51" modified="2008-01-15" version="1">MIGFIIRRVLAMIPVLFLVALITFFMMKQAKGGPFDQEKEVAPSTIALLNRKFGLDKPAWLNSAEFSNRLSTEGNPFLALRGLFDSQFGNYLINAVQGDLGPTYASKGTETVQDKIKETFPISLRLGMISLAFALLVGFPLGILGALRQNTIFDYFSLIISTIGFSVPTFVTGLLLLLVMSKVFDVAPIKDPSVWQGFSTSYIPPAIILGLGTMAYITRLTRSSVLEVKRQDYIRTARAKGLGDRVVILRHILRNSLIPVITILGPAVAGLVTGSFIIESVFRVPGIGSEFIGAIGSRDYSMIMGSTLFFSLLVALGNIMVDLSYGLIDPRIRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1M8</accession>
    <name>A9B1M8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen debranching enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1265"/>
    <dbReference type="EnsemblBacteria" id="ABX03913">
        <property type="protein sequence ID" value="ABX03913"/>
        <property type="gene ID" value="Haur_1265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1265"/>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026835_0_0_0"/>
    <dbReference type="OMA" id="QGTVWPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1287-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006451">
        <property type="entry name" value="Glycogen_debranch_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024742">
        <property type="entry name" value="Glycogen_debranch_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="PTHR10569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12439">
        <property type="entry name" value="GDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01561">
        <property type="entry name" value="gde_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDE_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="GDE_C" evidence="1">
        <location>
            <begin position="282"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="657" mass="73296" checksum="DB0AFD18FBDA31AD" modified="2008-01-15" version="1">MFGREILGHPAAALRREWIVTNGAGAYAMGSLLANAPIRKYHGLLIAALEPPLGRTLLVGGLQASAEYGSETYELSSFEYSDGRLSAGHCNLETWQLDGAIPTARYALAEAVLSQRIWMEDGANTTYLLLTHERGNDPIKLELRPLLSERDHHDTTVETDWQPNFAALTNGVLMTTPAGTQLRMLSDHATWQTESATWVEDIYYREELERGYPDTARLLQAGRFSASLQPGQSLTLVFSTETEPSTDGLAALAREQARQAQLLEQARLLHKAPDFIKQLVYAADQFMVRRAVQLPDGSTWQGWSVIAGYPWFSDWGRDTMISLPGLLMATGRATLAADVLRTWSHFLSQGMLPNRFPDVGAEPEYNTVDATLWFFQALRTVYQATGDIQLVADLYPKLVEIIDWHERGTRYSIKVADDYLLTAGEPHIQLTWMDAKFEDWVVTPREGKAVEINALWYSALRTLGEFATLLGNDQDVERFRCAAERVATAYRRFWSAEHGYLYDVIDGPHGDDPVLRPNQLFAVSVAHSPLDDATAKAVVDSCARHLLTSYGLRSLAPHDPQYLGRYGGDLKTRDASYHQGITWGWLIGPFISAISKVYGVEQARSYLQPFADHLRDAGIGSVSEIFDGDAPITPRGCPWQAWSVAELLRCSVELNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1P1</accession>
    <name>A9B1P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase, sigma 32 subunit, RpoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1278</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1278"/>
    <dbReference type="EnsemblBacteria" id="ABX03926">
        <property type="protein sequence ID" value="ABX03926"/>
        <property type="gene ID" value="Haur_1278"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1278"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_0"/>
    <dbReference type="OMA" id="HEQLGRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1300-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="303" mass="34190" checksum="35967C92A4CD8FDD" modified="2008-01-15" version="1">MMLHASNEPALDDGLQRYLNEIAETPLLAAEEEQKLTQIVHVARQAQPTPACRIERCPSCALFEQCVTKLKEPAHEQLVRANLRLVVSIAKRYRGFGLPFQDLIQEGNIGLMNAIERFDATKGVRFSTYATWWIRQAITRSLANQGRLIRLPVHRWELLIKVRRIETKLLQALGREPSANEISTALGVPEEKICDLLSIAQVPISLATPKNEETDMLLGDSLPDEDWEDELECLLTSIDAQYTRAMLNQLSEQEQEVLTLRYGLKDGKSRSLSEVGAVVGRTRQRIQQIEAGALQVLRTQLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R9</accession>
    <name>A9B1R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein DnaJ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2723"/>
    <dbReference type="EnsemblBacteria" id="ABX05361">
        <property type="protein sequence ID" value="ABX05361"/>
        <property type="gene ID" value="Haur_2723"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2723"/>
    <dbReference type="eggNOG" id="COG4235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084921_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2754-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="256" mass="28509" checksum="C836AC062955C81E" modified="2008-01-15" version="1">MSEQPDELDYRPLPSRRGNPTIKPIDVERAVRWRWLNGWLVLVITTALVISGTGGLIWLNTRPPAETAPQQMPLFASTILSEISDPNVRDQLLALDASTIQAQSVINQNPRDPNGWIMLGHAHYDFIQMIYEHAPNGQAYVQNLSRWIQASDAYSQALALDTFQPLIRSDRAVALARYGIGFGNPFYSEQALAEAETALSQDDQTLLVLLNVGRVYALLPEPRMADAERLWRKVIELGPTSLQAKLAQSLLDGAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W4</accession>
    <name>A9B1W4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2768"/>
    <dbReference type="EnsemblBacteria" id="ABX05406">
        <property type="protein sequence ID" value="ABX05406"/>
        <property type="gene ID" value="Haur_2768"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2768"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2799-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="110"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1050" mass="119524" checksum="9CA5C247C139E6B0" modified="2008-01-15" version="1">MNVTHQPDDSAQSVPSLRIHVFGGLRIFIDNQRISDLATRKVEALLIYLVVNPYPHEREVLAQLLWNDLSAERTAGNLRLTLNQLRKVMDPFIEVTRHTIGLHPQARYWLDLQHCTQIFENPASPTNELASAIEHYQGDFLNGFYLRDADGFSSWQLQQVEYWRQQALVAIRRLIERYTVVSNYNEAIRWLQRLVTLDECDEVAHRQLMLLLMRTGQRHTALRQYRLLEQVLEREYGLKPEPASEALQRQIMATPAQRPHRLIRPTPMLYGRQTELERMTHWLAAERNQLLTIMGAGGSGKTQLALTFGWKVVNEYLGASSNGVFYISLVSADQQPRLLDAEPVLLAIVQTLNLPPPRTNDLVEHLILQLQQHELIIIIDNGELLATSARLALSSLIQHIPQLRLIIGSRERMRLQNEYVLELAGLAYPQINDDSGYSPLLAEQLQHFAAVDLFVHCLQRQGKSGDLADYSHADRQAIGQICQMVHGLPLAIELIAPWMTIRSGHEIVEALSNDMQLFHSDVVDIPTRHRSIQAAFDYSWQLLDPHEQACLARLAVFPSSFNAETATIIAEVDLNVLANLRAKSLLTLEILQQQTRYALHPLLHQFAQTKLQGLAADQQTLYQRHARYFGQFSRQQEQLIHGNASQQGLMLLEQELDNIRGGWLWAVQAQQIHILGDYCIALHDFFAIRNREIEGQQLFAPAAALLSTLDHQDVEAEIVLIVVRIVSCYAEFHYILGELARSEALLQQCIDVLYRRQLQNVAELLFIYKQLGVITQRRGEYTRALDLLQRCLAQAESVNDPIKVSDTWLSIGAVLLAQGNWQAAEQAFQTCSDHYQAQKHLWGLCHSQRFLGVVALAQANYNLAQHHFEASLDLAYQLKTPLGEALIRDQMGMLALRREDFAQSAGYLHKAFAIFQELGVEAMIGRAAIHLAQLELAQRHFQYVQPWLARAIMVAQQRQEIPLLLECYATVLQFWAAVCDGEPSHWFKLWHSLSQHPACSAETKSLLNRLQLHQHSAGQSRPTIEVELSGIERYVALCLSQIEQSQSIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y5</accession>
    <name>A9B1Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein SsuA/TauA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2789"/>
    <dbReference type="EnsemblBacteria" id="ABX05427">
        <property type="protein sequence ID" value="ABX05427"/>
        <property type="gene ID" value="Haur_2789"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2789"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_2_0_0"/>
    <dbReference type="OMA" id="KTADFQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2820-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010067">
        <property type="entry name" value="ABC_SsuA_sub-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01728">
        <property type="entry name" value="SsuA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735193" evidence="4">
        <location>
            <begin position="32"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="41"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35089" checksum="9236169CFABD973B" modified="2008-01-15" version="1">MARRFSLGWQRLALALIVGLLASCGSTSNDAASDGQTSTRTLRIGYQKGGSLPILKGNGALESRLKDVKVEWIEFAAGPPLLESLNAGSIDLGSTGQTPPIFAQAAGTPLVYVASVAASPTGQALLVPKDSPIQSVSELKGKKVAFAKGSSAHYFAIDVLREAGLQYSDIEPAFLTPPDARPAFEGGSVDAWIIWEPYLTIALKATDARVVHDGSSLAPSHSYYLAAKSFAEQHPDLVSATLEEIQKVEQWSAQEPQAVAKILAPVIGVDAAILEEVAKKQAFGLSPINDAIVNEQQQIADTFFELGLIPKKVSIREAVWTWQPTQASAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B209</accession>
    <name>A9B209_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="9" type="ordered locus">Haur_4728</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4728"/>
    <dbReference type="EnsemblBacteria" id="ABX07359">
        <property type="protein sequence ID" value="ABX07359"/>
        <property type="gene ID" value="Haur_4728"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4728"/>
    <dbReference type="eggNOG" id="COG1570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023625_3_1_0"/>
    <dbReference type="OMA" id="WPAVRFE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="122"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="283"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="43535" checksum="4062C1DBCE4E31CC" modified="2008-01-15" version="1">MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWRSTALRLSYLPQDGMAILGHGKVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGLTERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAEVIIAPALVQGEDAAPSIVEALYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVADLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQMRLHQAHEQVNAQQQQLQRTIQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDRSLTNTSHVAVGDTINIQLHQGQLQATITELRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B246</accession>
    <name>A9B246_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
                <ecNumber evidence="9">6.3.2.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">D-alanyl-D-alanine-adding enzyme</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Alanine racemase</fullName>
                <ecNumber evidence="8">5.1.1.1</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">murF</name>
        <name evidence="13" type="ordered locus">Haur_4765</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the alanine racemase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="9"/>
    <dbReference type="EC" id="5.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4765"/>
    <dbReference type="EnsemblBacteria" id="ABX07396">
        <property type="protein sequence ID" value="ABX07396"/>
        <property type="gene ID" value="Haur_4765"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4765"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_335825_0_0_0"/>
    <dbReference type="OMA" id="MVKAFAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4823-MON"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="12">
        <location>
            <begin position="717"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="8">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="8">
        <location>
            <position position="738"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="109"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8 10">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX07396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="851" mass="90684" checksum="A699C6CC1BC58917" modified="2008-01-15" version="1">MIHVADLIAAGAHIAQAGDHIQWSGWAYDSRLAQTGNLFIALQTARADGHGFIRDAIAAGATGVVCQYAPSVIPASITVIICNDPLILLRSWAKAQFAKHAPRTVAITGSVGKTSTKRAIAQVLASRYSVLRSPRSFNADLGLSVTMAELAAQQWAVLEFGADHPGEIAQLCQLFPPEIGIVTNVGSAHLGAFGSQAAIAHEKAAIIQQLPAHGYAILNGDDPLVAAMAERTHARLLRVGQNAACEIRWGNVTSTVQSTQFTIHIPEHAPECIQLLASGVPSVQAAAFAIAVGYVAGLSLAEMREALADLRPAHGRFNPLVGRNGATIIDDTFNAAPESVYAALQTLGSLPARRRIAILGDMAELGAASARFHQQAGQIAAQHADLLITKGDQAALAATSAREASATYGYQINTMSVHSAAAVLAAVPTDLGAGDLVLVKGAAESRMEHVVAGLLAPEADPRQVLVRQEHVWRTVRIGLPDRPTTVRIDLDALASNVQAIRQAVGVPVMAVLKADAYGHGAVRSARTVLLNGASSLAVATLGEALHLRQADIAAPILILGYTPTWQMREALLNRISVALFDRHVAQSLHEQALALGLKAQVHIKIDTGMARLGLAVEQAVDFIEWLQGLAGIEVVGIFTHFANADEADASFFGLQLQRFQTLLDQLTQRGLRPPVVHAANSAAAMVHPSARYDMVRAGIALYGIDPSSDVHLNLQPVLEFQTEVAQVRELPAGSPISYGCTFVTSRISRIATIPVGYADGFRRAPQPWREVLIHGQRVPVVGRVCMDYAMIDVTELDSVQRGDQVVLIGQQGTDRIRAEEVAEWLGTNAYEVVSAILPRVPREPVEHFAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B288</accession>
    <name>A9B288_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol alpha-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4807"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07438">
        <property type="protein sequence ID" value="ABX07438"/>
        <property type="gene ID" value="Haur_4807"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4807"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_1_0"/>
    <dbReference type="OMA" id="FFCPNAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4866-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="183"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="372" mass="40614" checksum="7F4B6D1D2B6C3F02" modified="2008-01-15" version="1">MASDSLHIALVWPYDAAYAGGVTEHVNQLTHYFRAWGHRVTLIAPYSKGTPPDPDFIPLGHVTPVAVNGSVARVSLSLTLGPKIRQIFQTHHFDIAHIHEPFSPTLPTTFLSRSSVPNVGTFHAAGTRSIGYTSILALLRRLEPKLHGRIAVSAAAQEFAHRYFPADYTIIPNGVDVATYSTQQASFGLNQANPSVLFVGRFNEERKGFRYLLEAMSYVQRTRPDARLIVAGSGDPTPFLAAIRQWQIRHVEWLGYVSKAQLAALYQQTTLFCAPSTGGESFGIVLLEAMAAGAAVVAADNPGYRDVLDHRVQGLLVPARNAQALAVAILQLIEDQALRAAMAEAGTIKAQLYAWDRVAQRVFAFYRGILSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B8</accession>
    <name>A9B2B8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1315"/>
    <dbReference type="EnsemblBacteria" id="ABX03963">
        <property type="protein sequence ID" value="ABX03963"/>
        <property type="gene ID" value="Haur_1315"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1315"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049167_0_0_0"/>
    <dbReference type="OMA" id="GAMTEAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1338-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="343" mass="37960" checksum="A060498F4E1673FE" modified="2008-01-15" version="1">MSFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQGWALLDELVSLGLRVMVMSHRSSAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPPPALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQRLRQARKLRNISLVQANLDTKIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNLGGQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTLTPTPTATPSPTPTLTPTATPSPTPTLTPEPSPTLDPNAPTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F8</accession>
    <name>A9B2F8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1358"/>
    <dbReference type="EnsemblBacteria" id="ABX04003">
        <property type="protein sequence ID" value="ABX04003"/>
        <property type="gene ID" value="Haur_1358"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1358"/>
    <dbReference type="HOGENOM" id="CLU_890735_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1379-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025855">
        <property type="entry name" value="Replic_Relax"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13814">
        <property type="entry name" value="Replic_Relax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="312" mass="35532" checksum="32FB815BE78DF73E" modified="2008-01-15" version="1">MALSLSVGLNPIELHILLLIARLGRLLSRHLRTAWGHPFTVTIQTVNRTLVKLVDAKLLTYCEHFQSHGYDPRGALGWTRHGRLYSLTPLGWEIVKQAFPMLEEGSERLAPTMVNPQHQAEHQIEYAEVITSLIQSLPYVPGIVGMSSYIEMDLGPTARPRADGIVVVRRWADATQPDCERSSLYPWLGIGQQSKQIDQLYAIEIDRGTEELSIITGKAHSYGELYRSKYWEGRYSWPLIAFTVPTERRKRAVLDAWEIGWPGSQLLITTIDAVRESGVLTPIWTAQYTKHGERIQQPHRFLRAAWFEKIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J3</accession>
    <name>A9B2J3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1393"/>
    <dbReference type="EnsemblBacteria" id="ABX04038">
        <property type="protein sequence ID" value="ABX04038"/>
        <property type="gene ID" value="Haur_1393"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1393"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_729144_0_0_0"/>
    <dbReference type="OMA" id="PAQEIND"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1414-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="258"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="384" mass="42915" checksum="D1469EE3A6EB0E4D" modified="2008-01-15" version="1">MNRSPWPHRIMTGGMSSLLGILLALTVLNLQTLSQATRFFEQDDGIWNPTQLERDILRLRAVANDGGTNNPTLATEYQLRHNLVSNRLAAMNSFYSSAAESQYTSIEYQAFTVIQREFQRVPAQEINDLSSFSTIFINLEFQSRTMVNERRILVQQTANQQRTAFARVRTILFLIGGGMVIQAIFVIASLRRRFDTTLELAYQHLQARSTELETAQQELRTAHAASEARNTQLRDTLTALASSSAERQALTTQLSQMTFPVIPIIPQRAVLPLIGHLDSARMDQLASLLPRQIEQQQLRHVLIDLTGVTGIDPDTLTTLADLLQVSLILGCRPVFVGIPPHVAMDLQSIRSLPNAIQSFSTLQDAIDHIRSPAVTVPRPTLLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K9</accession>
    <name>A9B2K9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative flavin-binding monooxygenase involved in arsenic resistance</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2822"/>
    <dbReference type="EnsemblBacteria" id="ABX05460">
        <property type="protein sequence ID" value="ABX05460"/>
        <property type="gene ID" value="Haur_2822"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2822"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_1_0_0"/>
    <dbReference type="OMA" id="IFELHTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2853-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="39932" checksum="11A4FE8450DFAF6F" modified="2008-01-15" version="1">MANQTIVIGAGQAGLAAGYWLQQAKIPFQIIEAQASVGGSWPAYYDSLSLFSPARFSSLPGMAFPAPADSYPQRDTVVAYLQRYAEHFNLPIQTNTAISTIEPQNGGFRLTSSAGQVFHAGQIIAATGAFARPFMPELPNQAAFQGKILHSARYRDSADFVGKRVVVVGAGNSAIQIAIELAQVADVTLATRQPIRFQAQRIAGRDIHWWWWLTGFDRLALNTRVGRWIQQRTQGIVLDTGLYSRKINQNQPQRRAMFERFSATGVVWADGQPEAVDIVLFATGYRPHLSYLQGLNALDQAGLPLHRAGVSTTVEGLYYVGLEQQTNFASATLRGVGPDASRVVRHIQVRMQQPAGCCRWAMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S3</accession>
    <name>A9B2S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2886"/>
    <dbReference type="EnsemblBacteria" id="ABX05524">
        <property type="protein sequence ID" value="ABX05524"/>
        <property type="gene ID" value="Haur_2886"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2886"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_0_0_0"/>
    <dbReference type="OMA" id="YLCHATP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2917-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="30566" checksum="8337DB8E18C54A47" modified="2008-01-15" version="1">MRIAILSDIHSNLAAFEAVLADLQGQAVDHVVINGDVINGGPDPRECLDLARATGYTLLAGNHERYIRDYDLPVRPPEWASDLWKPSLWTVNQFSQAERAALHNLATTYHTDDLLVVHASPRHDQDSVFAITPQRELAAMFVDTPQTIIRSHNHIPQFRPWDGRMIVTTGAVGQPLDGNPWAKYAIAERKPQGWRVKHRVVIYDIETTVKRFHSSGYYEAAYPMSRLYLREVQLGTHHVVPFLRLHQQWLKADPQLSSEQAIKRFLEL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U4</accession>
    <name>PANB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="1">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">panB</name>
        <name type="ordered locus">Haur_3371</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B2U4"/>
    <dbReference type="SMR" id="A9B2U4"/>
    <dbReference type="STRING" id="316274.Haur_3371"/>
    <dbReference type="EnsemblBacteria" id="ABX06007">
        <property type="protein sequence ID" value="ABX06007"/>
        <property type="gene ID" value="Haur_3371"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3371"/>
    <dbReference type="eggNOG" id="COG0413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036645_1_0_0"/>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000096975" description="3-methyl-2-oxobutanoate hydroxymethyltransferase">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <sequence length="288" mass="30575" checksum="35BEC9D196C98F2D" modified="2008-01-15" version="1">MRTQLSDIQRMKDRGERLVMVTAYDYTSAQLVDRTDIPLILVGDSLGMVIQGNSSTVPVTIDEMVYHTKAVMRGSSKALVVGDLPFLSYTSPEQAIQNAGKLMQIGGCGAVKLEGGVNLAPTVRRLVDLGIPVMGHLGFTPQSVNQIGMRVQGKTVAHARQLLDDALALEAAGAFAIVLELIPAALAKAITARLHIPTIGIGAGVGCDGEVQVWHDILGLYSDHLPRHTKRYADLGSTIEQALTQYAHEVRERSFPTAANSSVIDANTLAEALGEQTVSVGASAKVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y2</accession>
    <name>A9B2Y2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3409"/>
    <dbReference type="EnsemblBacteria" id="ABX06045">
        <property type="protein sequence ID" value="ABX06045"/>
        <property type="gene ID" value="Haur_3409"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3409"/>
    <dbReference type="eggNOG" id="ENOG5032RIX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_692455_0_0_0"/>
    <dbReference type="OMA" id="WADLWSR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3446-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="445" mass="48894" checksum="F8BF075A03A26D46" modified="2008-01-15" version="1">MLSAEFSASNDLIQAIDQLLLAGFTNLNHSHQMSLQRVAQVYRDTPFEQAMLSAVTDLSNGVFQPAAFMLLAVARASLQAAQHDQLLQQIRVQLGRPINDQSTSKAVALAATPPLLGSVQHWLTDLAVMGFSRLEPAMINAFTPTLAQLQTNPDYLRTSAILSGWLHELQLQPEQLPLFRWGDLWTRAMLSTLSLNSTPPTQPVSGTLYPLGIEWRQHSTLVSLVVYAVLEADSKASLATISQSAYKVAAIQQDQLWLLFPELSLLFDSLSTAKALVLRDAASLPTGQLLWDAQTASLGAKYDLLDVAERYFGLNPKQSIAQAQLAPQQRHPVHVAEPVVLSNYQLNQTTEACTITTGEHSFMLELGLINGTEIDLAVLESAQRLFGLVRYDAGEWLLRPLATSLKKGKPLFIGLENGKVFKKAPKNNAVGILKERASRLLREKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B377</accession>
    <name>A9B377_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4910"/>
    <dbReference type="EnsemblBacteria" id="ABX07540">
        <property type="protein sequence ID" value="ABX07540"/>
        <property type="gene ID" value="Haur_4910"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4910"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_0_0"/>
    <dbReference type="OMA" id="IIFDLRP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4971-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="144"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="252"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="39720" checksum="DD9CC0129B7EFD86" modified="2008-01-15" version="1">MAADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFERYEKVDIKNFYTSAQEVQTRVQMMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAETTISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSMSNLVLRAEICERFLDHDTNQARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQGLETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAETLNDPTGKRNMGIASLRQQAEVLLRGQMGIESTVGRGTRVVAVVPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B9</accession>
    <name>A9B3B9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1438"/>
    <dbReference type="EnsemblBacteria" id="ABX04082">
        <property type="protein sequence ID" value="ABX04082"/>
        <property type="gene ID" value="Haur_1438"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1438"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025506_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1460-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="199"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="416" mass="47528" checksum="DB43A077FC6179D7" modified="2008-01-15" version="1">MNKETYLHDALQLPSQSFTYMVSQQLAAHYPDQGILQTGDCDFDVRSYAGAGLCEVQVHQQPYPQINYSWLRGEEGGEIARSLENAWQTITWQDQSFDLLLLSWTAYGTTYSLQWLIGASQAAVEAFFSAVCDWNTEIRDEIMVFDEGSWEKSQELYYAIKNASLDNLILPGTLKQDIFRDLQRFFESKATYEHYNIAWKRGIILVGPPGNGKTHMIKGLLNALDYPCLYVKSFDAQYSTNNANIRAVFDRARRSAPCIVVLEDLDSLINDTNRAFFLNEVDGFNANQGVVLLATTNHPEDIDPAIMNRPSRFDRKYYFSLPELAERLAYIEQWNTALHSSTQLTEAGIQQAAEVTEGFSFAYLKELFVSALMRWIDIKDQTDMDTVILEQATFLREQMVTEDPEAAEEETEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C4</accession>
    <name>A9B3C4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="4" type="ordered locus">Haur_1443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1443"/>
    <dbReference type="EnsemblBacteria" id="ABX04087">
        <property type="protein sequence ID" value="ABX04087"/>
        <property type="gene ID" value="Haur_1443"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1443"/>
    <dbReference type="eggNOG" id="COG0691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108953_0_1_0"/>
    <dbReference type="OMA" id="WTNHSAR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="18500" checksum="D5C4487814D572EE" modified="2008-01-15" version="1">MAKESKDSIEVMGDNRKARHDYFIQETYEAGIVLRGTEIKSIRRGQVQLRGSYARVQNGEIWLYDAHIAPYAETGELFNHEPMRPRKLLLHRREILKLHQKLATKGLTLVPLRIYLRGRLAKIELGLAQGKKLYDKRDSIADRDAKRQIERAMKNRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3G1</accession>
    <name>A9B3G1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1480"/>
    <dbReference type="EnsemblBacteria" id="ABX04124">
        <property type="protein sequence ID" value="ABX04124"/>
        <property type="gene ID" value="Haur_1480"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1480"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021993_2_0_0"/>
    <dbReference type="OMA" id="WAPLVPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1502-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="41220" checksum="8A18FCA01D1935A1" modified="2008-01-15" version="1">MAHSTPSLRRHSTLLVGLAYAAFISLGLPDGLTGVAWPSVRAEFGLSLDALGALVTSGTIGYLISSFSSGRVLTKIGVGWLLVLSCLATAVSLLGYGYAPTWIFMASLGILAGLGAGAIDAGLNTYAADNFNPRTLNWLHASFGLGAASGPVIMSSIISANQSWRVGYVVVGIAQLLLASAFAITRKQWQTQHSEAAVEPVASATMLQTLGLPATWLSILLFFLYTGLEFCAGQWLYTLLTTSRGMPPGIAGVWVSVYWGSLTVGRLLSGVIVGRISVLSLLRLSMLAAIIGVVLFWLNVAPWLTLIGIALLGLALAPMFPSFIALTPARMGPSHSANTIGFQIAAATLGGASITSSFGLLADGLGLEMLGTYLFVVALAMALIFEGLNRLKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X3</accession>
    <name>A9B3X3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3473"/>
    <dbReference type="EnsemblBacteria" id="ABX06109">
        <property type="protein sequence ID" value="ABX06109"/>
        <property type="gene ID" value="Haur_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3473"/>
    <dbReference type="HOGENOM" id="CLU_2395692_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3510-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="93" mass="10236" checksum="C4F531440AD95923" modified="2008-01-15" version="1">MRPIILALPAVFMCCGIIWMAAATTFLSNKTGRVTDLRRLFGRMSLIVGAVILVWAGVVIAMDIVKIAYPLVFAVVGGLLLFQGWAFSRFKLF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B421</accession>
    <name>RL14_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplN</name>
        <name type="ordered locus">Haur_4924</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B421"/>
    <dbReference type="SMR" id="A9B421"/>
    <dbReference type="STRING" id="316274.Haur_4924"/>
    <dbReference type="EnsemblBacteria" id="ABX07554">
        <property type="protein sequence ID" value="ABX07554"/>
        <property type="gene ID" value="Haur_4924"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4924"/>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_0"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000144284" description="50S ribosomal protein L14">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <sequence length="122" mass="13383" checksum="5F7C6AE8AE5C2925" modified="2008-01-15" version="1">MIQQESRMRVADNTGAKELLCIRVLGGTKRRYASVGDTIIATVKQANPGGSAKKGEVVRAVIVRVKKGYTRPDGSMIQFDDNAAVIINQQGNPRGTRIFGPVARELREKQYMKIISLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B447</accession>
    <name>A9B447_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4388 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4950"/>
    <dbReference type="EnsemblBacteria" id="ABX07580">
        <property type="protein sequence ID" value="ABX07580"/>
        <property type="gene ID" value="Haur_4950"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4950"/>
    <dbReference type="eggNOG" id="ENOG50349QQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1118962_0_0_0"/>
    <dbReference type="OMA" id="AIGRMFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5013-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4388" evidence="2">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="27020" checksum="62428D6ACC271D4A" modified="2008-01-15" version="1">MELTGTFNSFPLRELLELMQQSSMCGELEIVGKHGRGLILTRDGLVRHAEYNDKVGPEAVWLLFEEPNAEFAVRDLRELTQETMLSDAMSLCDEAEDRARSWSELRIFIPSDNAIPYIRNGATPSQPLDSMAVAVARTINGESSIRQIAERLIIEPIDVSRAIVRLIKAGVVAIMGVDPAKSLETKVLEPTTASMPLASLTPTLTPAKQPELTTAPLPTQPAATPTSDISRPNQGGLLGRLAQGPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>A9B471</accession>
    <name>A9B471_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">clpB</name>
        <name evidence="12" type="ordered locus">Haur_4974</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4974"/>
    <dbReference type="EnsemblBacteria" id="ABX07604">
        <property type="protein sequence ID" value="ABX07604"/>
        <property type="gene ID" value="Haur_4974"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4974"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_0"/>
    <dbReference type="OMA" id="SKMMQGE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="11">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="414"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="859" mass="95710" checksum="BD2FA4E92653553A" modified="2008-01-15" version="1">MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQALVAAVNDEIRRLPRVSGTQMQPGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERAKGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKYQALEKYGRDLTTLAQRGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLIALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNMLKPALARGELHTIGATTLDEYRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYETHHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAAAKLRMEITSDPVELDEIKRKRMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEKIDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEEDIAQVVAKWTGIPVSKLLEGELQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPNRPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMSEYMERHAVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVIMTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDIQVDRLSKRLSERKLKLVLNEAARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGKFPGGTTVNVDVKNGKLSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A0</accession>
    <name>A9B4A0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0005"/>
    <dbReference type="EnsemblBacteria" id="ABX02657">
        <property type="protein sequence ID" value="ABX02657"/>
        <property type="gene ID" value="Haur_0005"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0005"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_565933_0_0_0"/>
    <dbReference type="OMA" id="FARNKPD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="482" mass="51777" checksum="EB082D92C4871E93" modified="2008-01-15" version="1">MADKESILQLGIEAARAGDKEEARKLFRLLTRETPYDPQAWLWLAGVAEDREEKRAALEKVTELDPSNELARQGLDALGGPAAKSAAPTPPPAPEPAPVFVEPATTTAFDDFDVDWGQPSPRNVEPTPAPAAKKAEPARTRELTPDEEFAMSLDSLGSYSNAMSDRQKSSGGDSSVDFDIPDFGDDLDLDAYMNRERVDISTIEVKPEEAKKPVRRSPTLSAATAESNNVTPKGGKRKTTEGSATLKRALIGIFIMVVFVFILWQVFGSKGDQGPVAGRSTAEPTVIGGPTSPISPTVDLALATPIVEPTIDPNAPPPIEVVPTVDPNAFPVDQQLGSAQPAFLPSDGTIPLNIDGWFFNYAGGNLIADGNAINLQPQGRWVAVRLLMADTFGGRTIPADLVVLKDAQGRVYRANLDASEAVTNVYPDFVNRGFPYINQKQTAPGGNFTIALVFDVAPDATDLVLFSPQYLDQGYYVRGNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4F4</accession>
    <name>A9B4F4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0059"/>
    <dbReference type="EnsemblBacteria" id="ABX02711">
        <property type="protein sequence ID" value="ABX02711"/>
        <property type="gene ID" value="Haur_0059"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0059"/>
    <dbReference type="eggNOG" id="COG1878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_3_1_0"/>
    <dbReference type="OMA" id="GHPTHKT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-59-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="23166" checksum="76EF0F44474F1CF3" modified="2008-01-15" version="1">MAHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFINNDLAVESLELDRFVGDCYVVELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEPLRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEPGNPTHCILLGGRVAILEGINLTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-01-20" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J6</accession>
    <name>T23O_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan 2,3-dioxygenase</fullName>
            <shortName evidence="1">TDO</shortName>
            <ecNumber evidence="1">1.13.11.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Tryptamin 2,3-dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan oxygenase</fullName>
            <shortName evidence="1">TO</shortName>
            <shortName evidence="1">TRPO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan pyrrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kynA</name>
        <name type="ordered locus">Haur_1517</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="1.13.11.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="1">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B4J6"/>
    <dbReference type="SMR" id="A9B4J6"/>
    <dbReference type="STRING" id="316274.Haur_1517"/>
    <dbReference type="PRIDE" id="A9B4J6"/>
    <dbReference type="EnsemblBacteria" id="ABX04161">
        <property type="protein sequence ID" value="ABX04161"/>
        <property type="gene ID" value="Haur_1517"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1517"/>
    <dbReference type="eggNOG" id="COG3483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063240_0_0_0"/>
    <dbReference type="OMA" id="WRWRNDH"/>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01972">
        <property type="entry name" value="T23O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0223">Dioxygenase</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="chain" id="PRO_0000360117" description="Tryptophan 2,3-dioxygenase">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="34"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01972"/>
        </source>
    </evidence>
    <sequence length="260" mass="29916" checksum="900AE7463FDE204B" modified="2008-01-15" version="1">MSQALTYASYLKIDELLNLQTPRSHGPEHDELLFIVIHQVYELWFKQILHELDYLCDLLRANDTGRANQSIRRILTILKTIVAQVDVMETMTPLQFNAFRGSLESASGFQSLQFREIEFVLGYKRPAILQHFAALPSHERLEQRYQEPSLWDSFLHYLQLNGYAIPSEQIGRDVTQSLVASPAIQTILITVYRQNPLVSNLCERLIDLDEGFQEWRYRHVKMVERTIGMKQGTGGSSGAAYLASTIKPFFPDLWAIRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4L9</accession>
    <name>A9B4L9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1541"/>
    <dbReference type="EnsemblBacteria" id="ABX04184">
        <property type="protein sequence ID" value="ABX04184"/>
        <property type="gene ID" value="Haur_1541"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1541"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_1_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1565-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="30"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14947" checksum="E2CDC3A2F5F7A222" modified="2008-01-15" version="1">MLISSAFSAGQFWILFKNWQRNQAAAPPAQKIANLADIPVGGMLLFRYPNEHEPCILVRPDENTLVAYSQKCTHLSCAVIPNVAENKIVCPCHQGYFSLDEGRPLAGPPQHPLPRIHVEVQGDEVFATSVELRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4M3</accession>
    <name>A9B4M3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1545"/>
    <dbReference type="EnsemblBacteria" id="ABX04188">
        <property type="protein sequence ID" value="ABX04188"/>
        <property type="gene ID" value="Haur_1545"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1545"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101283_0_0_0"/>
    <dbReference type="OMA" id="WANQQIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1569-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="18886" checksum="C7BCA1E8948100C8" modified="2008-01-15" version="1">MNITAFRHFYDYHFAQNRQLLDDYVAQLSAAQFVQAVDYSLGSVRNQLVHLMSVDETWFSGLRGGEFPEPLDPNNFPDLATLRAYWANVEAMMRDYLANLQDADLQTKPLDGEDENLIVWQVLLQVVNHGTDHRAQILRLCHDFGLKTSSQDYIFYVYEHPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T2</accession>
    <name>A9B4T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05655">
        <property type="protein sequence ID" value="ABX05655"/>
        <property type="gene ID" value="Haur_3017"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3017"/>
    <dbReference type="HOGENOM" id="CLU_2316447_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3049-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="11391" checksum="16CB5515BB5E5DD9" modified="2008-01-15" version="1">MLAPSQPRSRNMADYHVPQADQTHASFACPECGSKKQSMQPLLTSGIHMFRYFVQCIDCGYEYTYKKPLPNLNRQLRKDPLAWFMLAAMLLLLAFMLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V1</accession>
    <name>A9B4V1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3036"/>
    <dbReference type="EnsemblBacteria" id="ABX05674">
        <property type="protein sequence ID" value="ABX05674"/>
        <property type="gene ID" value="Haur_3036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3036"/>
    <dbReference type="HOGENOM" id="CLU_979243_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3068-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731885" evidence="1">
        <location>
            <begin position="24"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31370" checksum="6D062109A8EEA657" modified="2008-01-15" version="1">MRRLTQFALFLGLICLFSTASYANPNVPTAATLAWSSTFASTAEGIDVWLRINVVGAAPTDNVNLSFIYQTFGQTAQASHDYEQTAWPNGTKGTITGNKRVAYIKINIKRNDYFEPTETFQVELRSDAANTVITGPARVMVTISRARLMNPIAGILESCLNGGEPNNDFPVSAGQIAINGGWCNTTFDKETVNAFDYYHLVQSTAGSITIRLENTTPDQHDIDLYLFYRDGQGDYQNYRQSINGNQQAEYIEAPLAAYTNYLIGVHWVSGSGSKIPTYRLSVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W0</accession>
    <name>A9B4W0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3045"/>
    <dbReference type="EnsemblBacteria" id="ABX05683">
        <property type="protein sequence ID" value="ABX05683"/>
        <property type="gene ID" value="Haur_3045"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3045"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="YPRITWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3077-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31106" checksum="463143310FE41C12" modified="2008-01-15" version="1">MAAVASQAHIRLQSATSLAPALEVRQLNIRYDQRTVLSDVSFQAQSSQLIGIIGPNGAGKTSLIKAILGLIPSTGQILVAGQALAKRSRKVAYVPQISAVNWRFPASVRDVVLMGRYGQLGWLRRPKKADYALADAALEQVNMQDFAERSIADLSGGQQQRVFLARALAQEPDVLLLDEPISGVDVPTQEVILHLLRDLSSAGRTLLVTTHHLQHLEHHFDALLCLNQCLIAYGPPTAVMTREVVEATFGRSLVLVPSAERIILDCNHGNCTEKQTLINRDGSANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B568</accession>
    <name>A9B568_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3569"/>
    <dbReference type="EnsemblBacteria" id="ABX06205">
        <property type="protein sequence ID" value="ABX06205"/>
        <property type="gene ID" value="Haur_3569"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3569"/>
    <dbReference type="eggNOG" id="COG0116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052320_0_0_0"/>
    <dbReference type="OMA" id="DERMRHR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3606-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UPF0020" evidence="2">
        <location>
            <begin position="251"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="46884" checksum="30346FA74D8CBCE4" modified="2008-01-15" version="1">MPFQRPKRRSPQRGPQSNAARPARPGRPGSRPNQAPTRGPRHDPAGRPAGAAPAGAVRQRAFVKQPTVDMSRPLFAVQTQPGVGQLLLAEINATLQKPMLVAQRHVTQKDDMLLFHTDTNSKELFNLRTAEDLFVVAARAFNISPDQSGLKQIHAAVKNSMLVPTALRVFTLNGGRTPKMTSFRVVTRVTGKQDFARKAVGIAVADAVRDNWPGRWKLVEEEADVEMWVTLFGSEIVVAIRLSTGGMRHRIQRVVDRPAALRPAIAAAMVRLSNPQPTDVFLDAMAGTGTIIAERAAVGPFERLIAGDKSREAVKALSRNLASVGGDLAIRRLDATDLPFQPGEINKLVTNLPFGKQVNNIDELHQLYSGVCAEWARIVAPGGMIVALAAEIDVLREKINATPELRVRGTFPIAVLGQTATIVQLERRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B572</accession>
    <name>A9B572_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3573"/>
    <dbReference type="EnsemblBacteria" id="ABX06209">
        <property type="protein sequence ID" value="ABX06209"/>
        <property type="gene ID" value="Haur_3573"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3573"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_729145_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3611-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="42763" checksum="4C6BAD26E5F04E20" modified="2008-01-15" version="1">MKGVDDALDKHPNQPITESFMKRLLLHIRCFLMAGGNLYALRTGLLPCLLAWTAWRHPHYVALALGLSSFSYLVHYLRYAERWPIGRMPWIDQWAEFGLALLMPLIATGWYSPWLFDTWLMLAATAHQLSRRSSPTLGIVWLGYSVALFASNPLGQTNPMLFCMLVLGVPAILLISIKPQEVEPIPQPSSRMLSSLQTAQRRFELIRAIIDHAQRSAMVEAVYHQAQHGVRDLSLLIDDITPQAVQPSLIERFKPIIERWKINNGIDVAFHTTIVPQQLNPSIEALFVRTLEETLNNVARHAQASLVEISLRSDEQHISLIVRDNGIGLVYGTTQRAGSRGLRWLRYRAQEINGYLDAYDGVDGGLVVQLSIPLTVYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B594</accession>
    <name>A9B594_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsgA</name>
        <name evidence="10" type="ordered locus">Haur_3595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3595"/>
    <dbReference type="EnsemblBacteria" id="ABX06231">
        <property type="protein sequence ID" value="ABX06231"/>
        <property type="gene ID" value="Haur_3595"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3595"/>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033617_2_1_0"/>
    <dbReference type="OMA" id="CLVAAYD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04466">
        <property type="entry name" value="S1_YloQ_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031944">
        <property type="entry name" value="RsgA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16745">
        <property type="entry name" value="RsgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="77"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="8">
        <location>
            <begin position="86"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="176"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="33813" checksum="A2241F5FBF4CD69B" modified="2008-01-15" version="1">MNGTIMRAQSGFFWVKLDETGETLRCTLRGRLKKTKQYSDLATLGDFVRITPTIPNEGVVEEIYPRRSKLARTAIKGAHFEQVIVANLDIVLITFAVAHPEPHVRMIDRFLVIAEANNLDVAIIANKCDLVSDSHQKVFGIYEQIGYPVFYTSVSTGQGIEQVQEIIHNKISAFTGPSGVGKSSLLNAIQPGLNLRTGDVSDAVNKGQHTTVAGELVPLHAGGFVADTPGIRELGLYQMEPDELEWCFREFRPFIDECGFSDCTHTHEPECAVLAAVEAGQISSARHQSYQKLRDHTAEQSASQRF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C4</accession>
    <name>GATB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatB</name>
        <name type="ordered locus">Haur_0097</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5C4"/>
    <dbReference type="SMR" id="A9B5C4"/>
    <dbReference type="STRING" id="316274.Haur_0097"/>
    <dbReference type="EnsemblBacteria" id="ABX02749">
        <property type="protein sequence ID" value="ABX02749"/>
        <property type="gene ID" value="Haur_0097"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0097"/>
    <dbReference type="eggNOG" id="COG0064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019240_0_0_0"/>
    <dbReference type="OMA" id="ARKWWMG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000095215" description="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B">
        <location>
            <begin position="1"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <sequence length="483" mass="53074" checksum="B94E13E79696C7E4" modified="2008-01-15" version="1">MKYTATIGLEVHAQILTKSKMFSGCNAAYASAPANSCIDEVSIGLPGTLPVVNQEAIRKAALLGLALNCEIPEYCEFSRKSYTYPDLPKAWQITMYDKPICINGELEITLGNGETKRVGITRAHLEEDTGMLQHGDETHSLVDYNRSGVPLLEIVSEPDMTTPEEARLYATKLRQILVFLGVNSGNLEEGALRVDANVSIRPEGQKEFGTKVEIKNMNSFRNLERALVYELERQEKVLREGGTIIQETRGWDDAAGITLSQRSKEHAHDYRYFPEPDLPPLELSREWVAERRAELPELPDAKFARYLSEFGLSKQDAALLSGERETADYFETIVATAGAANAKPVANWITGELFRLIKDGAETLAEVAKRVTPANLTSLIDVVAKGEIGSTVAKQVFEEMYRTGETPTAIINAKGLRQISDSSVLTQAARDAIAANPKVVADYKSGKLPAIKFLVGQVMRATKGQANPQVVEEALKTELDATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E7</accession>
    <name>A9B5E7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ordered locus">Haur_0120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0120"/>
    <dbReference type="EnsemblBacteria" id="ABX02772">
        <property type="protein sequence ID" value="ABX02772"/>
        <property type="gene ID" value="Haur_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0120"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113663_5_1_0"/>
    <dbReference type="OMA" id="DAFSEMR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX02772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="72" mass="8269" checksum="DC00C185627DD5C1" modified="2008-01-15" version="1">MVAVATEEKEDYKPNPIAQFFRDAFSEMRKVVWPSREETQRLTLVVIGISLLVGSILAVFDLLFETLVRLIQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E9</accession>
    <name>RL11_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplK</name>
        <name type="ordered locus">Haur_0122</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5E9"/>
    <dbReference type="SMR" id="A9B5E9"/>
    <dbReference type="STRING" id="316274.Haur_0122"/>
    <dbReference type="EnsemblBacteria" id="ABX02774">
        <property type="protein sequence ID" value="ABX02774"/>
        <property type="gene ID" value="Haur_0122"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0122"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_2_2_0"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000195652" description="50S ribosomal protein L11">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <sequence length="141" mass="14666" checksum="833A16952C86656B" modified="2008-01-15" version="1">MAKKVTAVVKLQLPAGKATPAPPVGPALGATGINIMAFCKDYNEKTSAQVGTIIPVEITVYSDRSFTYILKTPPAADLLRKAAGIQRGSGKTGTQGAGSITRAQLRQLAETKMPDLNANDIEAAEKIIAGTARSMGIAIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R4</accession>
    <name>A9B5R4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1654"/>
    <dbReference type="EnsemblBacteria" id="ABX04297">
        <property type="protein sequence ID" value="ABX04297"/>
        <property type="gene ID" value="Haur_1654"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1654"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_810788_0_0_0"/>
    <dbReference type="OMA" id="DGHIYTA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1678-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="37326" checksum="2B90460482B8878A" modified="2008-01-15" version="1">MSRRKKRPTSAQPVAKASQIASTKATKAQHRRSLLAVGSVLAVLSVLGLGLWWVNRSSATASNFPVGEVTSCKQIPPFAQAQGFGVNAVLDTQARRVRGMVMYDLTSDGQEASQPAPYQHPSWSKAGYLSSPILDRDGAIYVGAVPWVSILYNPPAAANKVYRIDPRTAELSELLDLPTAAPANNTNPYGILALNYDCNTHSLYVSSVLGSTKDQQFGRIFRVDLATNKASIVIDGVDSFGIGVYNGNTGKRLYYALARQPQIYSIALDNQGNPTGQPRQEIDFSGQGYHGDERGRRISFGDATMQVRIVQFDYTLTAVTNPNETTLSYRYNPQTDSWQAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B644</accession>
    <name>A9B644_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3619"/>
    <dbReference type="EnsemblBacteria" id="ABX06255">
        <property type="protein sequence ID" value="ABX06255"/>
        <property type="gene ID" value="Haur_3619"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3619"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_2_0_0"/>
    <dbReference type="OMA" id="ATFTHEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3658-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="21"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="42612" checksum="0A3F5B12CA0597D7" modified="2008-01-15" version="1">MAFFRQRFELARGLAGTNLRSMEGLRGIAVFLVFLVHFRSSIQPWLFSDSPTATINNALAMVGNTGVDLFFVLSGYLIYASLIKRQQAYMGFIGRRIRRIYPTFFVIFMVYLGLSILFPAESKIPSGVTAATLYFIQNLIFLPGLLPIEPMITVAWSLSYEVFYYLIMPVIVVAIGLRGKTPQWRIGFFSVVGVVLTAVCIIWQGPLKLAMFIAGILLHELLESYRERTPAAWLGLLGLVMGTCAPLLPLTGTLGNAIRFTLIFSGFLLVCWHCFSQTESWLKQALSWTPLRWLGNMSYSYYLIHGLALHAGFMLLAKLLPATPTAGWFFWLILPLMFGLTLVVGAALFIVVEHPMSLKNNAKPAVEPRDPEVRPALNADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B668</accession>
    <name>A9B668_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06279">
        <property type="protein sequence ID" value="ABX06279"/>
        <property type="gene ID" value="Haur_3643"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3643"/>
    <dbReference type="HOGENOM" id="CLU_1576340_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3682-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="17853" checksum="D01D6789332E8F0D" modified="2008-01-15" version="1">MIESGSTALDSHTYSAVELVRYALHDPAKFKQVDAMLVQRMPDPAAAKLLIAAFEAGTAPAWLVAYLIGRISADCGYATARTIVLATPGQLAESYAAVAMVRIRGARAFADLAELLKTAPQRASREAAASGLAEFGSVEATELILAAGQAQTIRATIARRLLTPTPRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B697</accession>
    <name>A9B697_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3672"/>
    <dbReference type="EnsemblBacteria" id="ABX06308">
        <property type="protein sequence ID" value="ABX06308"/>
        <property type="gene ID" value="Haur_3672"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3672"/>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063816_1_0_0"/>
    <dbReference type="OMA" id="FMTTHSQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3711-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="28"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="378" mass="43807" checksum="9FF2F1BE809E6F89" modified="2008-01-15" version="1">MAELQLNSLIIQNFRGFENFQINQLGRVNLIVGKNNIGKTSLLEAIWLYANRGSSVTIYDILKDRDEHRVFNLNPTTEQTQQEILAIKNLFYQRNDFTDQTQTLQIGNTRENYLQLQARWYQVEMDDHDNLTPKPIKYADLDFSDEPFFGVEVVMYRNGKSAQKIRKYPIYRQNPTQNWNEIVCNFITSNFVHRYQLSKWRDTTLIEGLENYALEALQIIEPSIEAINMITVEEKVTTDFSISSRLVPIPVVRMVGATKFIPLRSLGDGLNRMLILILAMVNAKDGFVLIDEIENGLHYSIYPNVWKLIFKLAETLNVQVFATTHSKECLNAFNKTNKDQAAQSGRLIRLGRKKGNIVATEYNQKDMQVILERDIEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6A3</accession>
    <name>A9B6A3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ordered locus">Haur_3678</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A9B6A3"/>
    <dbReference type="STRING" id="316274.Haur_3678"/>
    <dbReference type="EnsemblBacteria" id="ABX06314">
        <property type="protein sequence ID" value="ABX06314"/>
        <property type="gene ID" value="Haur_3678"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3678"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_2_0_0"/>
    <dbReference type="OMA" id="RSINMTI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="10979" checksum="50BF664E70B8EFEC" modified="2008-01-15" version="1">MSDFRIRPLADRVVIKPQAKEEKTKSGLFLPDTANKEKPQEGLVVAVGEGKLDDNGKRVPVAVQVGDRVLFAKYAGTEIKLDDEDYLILAEKDILAVVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D0</accession>
    <name>A9B6D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0181"/>
    <dbReference type="EnsemblBacteria" id="ABX02833">
        <property type="protein sequence ID" value="ABX02833"/>
        <property type="gene ID" value="Haur_0181"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0181"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_929906_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-184-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="32672" checksum="6B62F6860E84A5A2" modified="2008-01-15" version="1">MTIDDELAKGIAAVRAGQRELARQHLQKVLLTDSKNESAWLWLSGVVETRTQKRDCLQLVLSINPNNTAARRGLEELAQSEAADFLSTFEPPAPPPAPPPAPPPAPPPVAPTPTPAAPISSMASFEEPPAAMFEPVPIELDQPMAGFGFAPMVTEVTPEPAPVLGNMPTNVPKPPQNLEAPCAFCGTPTQSTGECSNCGTEQTFDCPNCGHVLDVRENWICECGHSFENFLTPERKLDRERLGQMYSDRDFPAAAVKQWKAALPTSRRPQQLHAAIGRVYDNLGLYEQAEMHYRLSKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F4</accession>
    <name>A9B6F4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0205"/>
    <dbReference type="EnsemblBacteria" id="ABX02857">
        <property type="protein sequence ID" value="ABX02857"/>
        <property type="gene ID" value="Haur_0205"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0205"/>
    <dbReference type="eggNOG" id="COG1690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_1_0_0"/>
    <dbReference type="OMA" id="PGSMGDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-208-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="337"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="361"/>
            <end position="364"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="440" mass="47711" checksum="537D56193CBB7149" modified="2008-01-15" version="1">MKLNVLLKPWRGDKRFTAIAKYAAALKKSGSKDLQIVAQVEAEFGKPTELARINEQPQPYKAYGQIGVDIEAAALEQLLLALRLPIAAQGALMPDAHPGFALPIGGVFAAHNAVSPMMVGVDIGCRMHLTIFAEAPMEIQRQREQLFRDLADVTVFGSGASRKRGPDHPILGIKHWNITAQTRSLREKAIAQLGTSGGGNHFANIVVGERIGENDLPRQFVGLLTHSGSRGVGYAIAKHYSNIAVQETARQAHVPKMYEWLNLDSEAGQEYWAAMELAGAFAQANHEVIHRLFAQRTKLQPITTIQNHHNFAWREGDLIVHRKGATPAGVGVRGVIPGSMASASYVVEGLGNPEALHSASHGAGRLLSRSKARATISPSEAKKVIKAHGVHVEGWSIDESPLAYKDIERVMELQIEADLIKPLARMKPIAVIMAGEAGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H1</accession>
    <name>A9B6H1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">trpB</name>
        <name evidence="13" type="ordered locus">Haur_0222</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0222"/>
    <dbReference type="EnsemblBacteria" id="ABX02874">
        <property type="protein sequence ID" value="ABX02874"/>
        <property type="gene ID" value="Haur_0222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0222"/>
    <dbReference type="eggNOG" id="COG0133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_3_1_0"/>
    <dbReference type="OMA" id="HGMKSYF"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="57"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX02874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="43390" checksum="1C8A42456EFB4877" modified="2008-01-15" version="1">MTDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGRPTALTYARRLTEELGGAQIWLKREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQHGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGADVRGVSTGSKTLKDAVNEAMRDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGSNAIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIANTHSISAGLDYAAVGPEHAWLHDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAIAEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N9</accession>
    <name>A9B6N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04348">
        <property type="protein sequence ID" value="ABX04348"/>
        <property type="gene ID" value="Haur_1705"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1705"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045644_1_2_0"/>
    <dbReference type="OMA" id="IPRRYQH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1732-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="35636" checksum="14D598BE2EE77C1C" modified="2008-01-15" version="1">MDTLVWMWIGFNVFVLAMLALDLGVFHRSAHVVSIKEATLWSVAWIGLAAIFNLGIYLFWQQLVPQSSYTNSEAALAFMTGYLIEKSLSIDNIFVFVLIFGSFAVPAQYQHRVLFWGVLGALVMRGAMIGAGAALIREFHWIIYIFGAFLIVTGIKMALHQEQTLDPKNNILVRTFRRLMPVTDEYEQDKFFVRKAGVLMATPLFLVLLMIEATDLIFAVDSIPAIFAVTQEPFLVYTANVFAILGLRSLYFVLAGMVHKFHYLKLGLAFVLSFVGVKMLLVETAFKIPSGIALGVVATIIVIAIGASLIRAKRLENAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6V9</accession>
    <name>A9B6V9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ordered locus">Haur_3190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3190"/>
    <dbReference type="EnsemblBacteria" id="ABX05827">
        <property type="protein sequence ID" value="ABX05827"/>
        <property type="gene ID" value="Haur_3190"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3190"/>
    <dbReference type="eggNOG" id="COG0481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009995_3_3_0"/>
    <dbReference type="OMA" id="MVQIAIQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="5"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="600" mass="66527" checksum="211C5E9488F02F6F" modified="2008-01-15" version="1">MAEQTHIRNFSIIAHVDHGKTTLSDRLLEVTQTLSSREMRAQTLDAMDLEREKGITIKMHPVRLEYTAKDGQQYALHMIDCPGHVDFSYEVSRSLQACEGALLIVDASQGIEAQTLANVYLALENNLEIIPILNKIDLPGAEVERVSEEVEHVLGLPREEIILASGKEGTGVPEILEAIVARIPPPKGINEAPARALIFDSQYNAYKGVIAYIRVVDGTIRAGDKLRLMGTEVLTEAMEIGFFRPGMVAGQALSAGEVGYIATGLKSVRDCQVGDTITLVDNPAKTSLAPYEPAKPMVFAGLYPVDSGDYTLLRDALDKLRLNDAALSFEPETSAALGFGFRAGFLGLLHMEIVQERLEREYNIDLLVTAPSVEYQVLTNAGEILIIDNPSELPDVGQISQIEEPMMSISIIVPTRYIGVVMELVTGKRGIFQSMDYLDKERVVLKYEIPLSEIVIDFYDSLKSRTQGYASLDYHLSSYRASDLVKLDVLVNGTAVDALSMITHRDNAYRQGRQLVEKLQKLIPRQMFEVPIQAAVGSRVIARETIRAMRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKMVGNVEIPQDAFMAVLKLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B705</accession>
    <name>A9B705_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3236"/>
    <dbReference type="EnsemblBacteria" id="ABX05873">
        <property type="protein sequence ID" value="ABX05873"/>
        <property type="gene ID" value="Haur_3236"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3236"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004327_1_0_0"/>
    <dbReference type="OMA" id="HICIDEL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3271-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="695"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="957" mass="108677" checksum="8A1D4F7C6DF575D1" modified="2008-01-15" version="1">MHDVERIRQKIINLQARRAQESDQDLIEALDQMIGQHQHQLSLLAQQAAAVLEPPAPAATQGQVYGSSVMTNLGHVWINQVFNAPLSTGERTDQLILHYLAHVQGNADRLVLGTDVQDSDQERMSLQRVFTMLQADFYGPIAGDALLQSLLLGSSQPRPQLQDSILKALNQIQHQRSVILGVPGGGKTTVVSYLASAQAAALLDPSKAEFLHSQGWMHTKLVPVRVRLKHVQPPADPEQQTADAFWEVVTELQLAGRFGQRAINSDVGFQRIEVERQQRLQDAIEELLTNGNGLLLLDGLDEVQPEHLAAVKRCIEHAQRMFHKSRIIVTCRVFDYEHPLPPPFPSRQLYDWPTIQLMPFDLTAQHVYITNYYSELGRLHASHADIVSIRKKHAKLHAELTKSGMLHELTRTPLLLALTVHVNMVHTDLPESEGKLLHICIDELLKRRAPEAIAVSLEDLYDLVALLGYYAHSQEEIQGKALLSLQQINMVVQRYYSDRYPHPNQIHMLAQAVGNATLRLINSNGLLQEASNNQQDNPHYDFAHRLFQQFLAGMYLLNQERHDECIERAGSEHWRVCLHYMANFAPYIQKQSFIFGVIQDLLGGMPDEQVQGSHLLLAIGKAKVASAGRRNLWQQAVNHLKNIGGLSGSSRGVRRWAPPRIAFPTRLRAALVLGAIGDTRFIGEDGALIALTERVVCIHAGSVELEDPHSRPQTYSVERFWMSRYLLTNFEYSQFIAARGYLDDQWWQNDDARHWRRGDPSWLHGLPPWAAPRRLPDLWHNERFNHPTQPIVGVNWYEANAFCAWLTVQLRPQLDALGPNLVVRLPSEAEWQLAASQHSEREYPWGDEWRNDHANTSESELEQPTPVGMFPYGTWSDGPMDLAGNVCEWTNSINRDPELEPQTTRNRRLQHRDLMVAVRGGSWFHNRYFARCRSRLQHRPFSHGPNIGVRLIIGHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N9</accession>
    <name>A9B7N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1774"/>
    <dbReference type="EnsemblBacteria" id="ABX04417">
        <property type="protein sequence ID" value="ABX04417"/>
        <property type="gene ID" value="Haur_1774"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1774"/>
    <dbReference type="eggNOG" id="ENOG502ZBMH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1576690_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1802-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="18029" checksum="8894B1AC6A77AF75" modified="2008-01-15" version="1">MPNVNVFRGSDASLVLAVDDSSTAEGGLADALIGEYALSSVVGRLQNVQIVVQNDIRPYHEIGRRFATELRPGNITIAGTAERAHINGALIRLLLGDGSKSPPPTGAIAQPSFNIVINLVNPASPDNSSTLTIFGVKFDTWSFRLPEDDFVMETVTFKALRMSSAETSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X2</accession>
    <name>A9B7X2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1857</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1857"/>
    <dbReference type="EnsemblBacteria" id="ABX04500">
        <property type="protein sequence ID" value="ABX04500"/>
        <property type="gene ID" value="Haur_1857"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1857"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_70_2_0"/>
    <dbReference type="OMA" id="WATGMIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1886-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="962"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2986"/>
            <end position="3061"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="999"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="3021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3099" mass="338602" checksum="7DAE3B44A526E2FF" modified="2008-01-15" version="1">MKRSPELVALTAPFADLGLSSREAVGLSGDLQAWLGRKVAPTVLWEYSTIQALSDFLAHDQAQQLPLPKPKPSQASATSSSAIAIVAMSCRLPGADSPEALWQLLLEGRSAIGFVPADRWDAQALYSPEARTPGKINTRWGGFLDQVDQFDPQVFGISGREASRIDPQQRLALEVAWETFERAGIAPDQLVGSATGVFLGISSNDYARLQFAQLDQLDAYAGTGNAHSIAANRLSYVFGLQGPSMALDTACSSSLVAVHLASQSLLAGECEQALAGGVNLILNPELSVTFAQAQMLSGTGECHTFDAAADGYVRSEGCGMVLLKRLDVAEAAGDPILAVIHGSAVNQDGRSNGLTAPNGQAQQAVIRQALAKAQIQPDQLSYIEAHGTGTPLGDPIEVAALQAVLGERQQPCLLGSLKSNLGHLEAAAGIAGLIKLVLAFQQQIIPAQANFKQRNPQIELGSALEIATTPQPWYSFGSYAGISSFGFGGTNAHVILGAAPIQPKRLPQPSPAPIQLLALQANSETALRQLTERYQAYLAQTEVNLADICWSAYHQRATMRHRLIVSATDKIQMLERLQHAWQAQATGSIYAEQPQPAPRIAFVCSGQGSQYVGMAQTLYQTQPLVRQILDQANSILNEYLAIPLLDVLYQPDHGALLRDTRYTQPAIFVVSYALGQLWRSWGIEPVALLGHSIGEYSAAVLAGVWSFEQGLRLVAQRAQLMHGLPEHGAMLAIRSPLESIEPLLAQHQLDLAAINGPNAVVVAGSVAAISQCAVELNQLNITNKLLDVSHGFHSRLMQPMLADFQQVLSAYPAMAPQIRLIANLDGSWHEQAPSAEYWVEHTRQPVQFYRGLQSLVASGVSHMLELGGHSTLIDLGRQAGLPNLTWLASLRRQQADWETLYHAAATLLAHGCQLNWAAMNPDYQPQAVLLPTYAFDRQRYWFTEGTGMNQASAQPTPASASSRHSTILAELRSLTANLLHVKPEQINIHSSFVEMGADSLVMIDAGRAIESRYNVHITMRQLFEDLASLDALARFLDAHGTFEAEPAPSEPSVVPIVAQAQPVAPAAVTPVAAAGLEAVVQQQLALMQQQLALLAGQPAAVTPIQPVTPASATPATPVIKPASTPAAAAPKAYVPYQPVRPGSITANDLSSQQQAHLQQLIKDYTTRTATSKQLTQAYRAQLADNRESAGFRFSIKEMLYTLICERSEGSKIWDVDNNQYLDLTMGFGVNLFGHRPEITTQALANQLAQGYQLGPQTRLAGEVAQLICRITGMERVAFCNSGTEAVLTAIRAARTVTGRKKIALFAGSYHGFYDATLATAQAGAATRSVPLAPGIPQGMVDDIVVLDYVTPESLVTLEQLLPELAAVLVEPVQSRRPDLQPQAFLQAVRELTKTHGSLLIFDEMITGFRIAAGGAQAWFGIEADLATYGKIVGGGMPIGVVAGRGATLDALDGGFWQYGDDSFPQAETTFVAGTFCKHPLALASAKAVLTAIEHAGQGLYDQLNQQTASFAAEMNAYFAQAEAPISVVHFGSLFRFSFKQNLDLFFYHLLLQGIYIWEGRNCFFSTAHSTADVEWLKRAIRNAVEALQDGGFLPKPQRQLNQPHSFALSEDQYHLWVLGQLGQHEAIAYNLPTGLEIRGQLDLVRLEQAFNLVVQRHESLRTIIASDGTQQIVQPQQPITINFSDFSSAANQQQALDQWFTQHNQQVFDLSQTNPLRCNVAQLGPDRYALSLVVHHLLVDGWSVGVILQEVAQMYQVLSDGQTPQLAQPLQFRDYLAWKAGRDLTTQANFWQALFAELPAPLALPTDYPRPALKSYVGQRVMQVLEPASYQALKQLSRQSGATLFMVLLAGYQLLLHRLTGQNDLVVGIPAAARSFEGSETIVGYCGNLLPLRSRLQAEQSFSDYLHLTRQQLFDAYENEDYSLAQLLAVLNPMRDASRSAIVETLFNFEPPTPAPNFGGLETSFVPQSISATALDLSVNVIELNQQLVVYCDYNSDLFEQATIERWLGHYQTLLLSAAQQPTSPAERLALLNPSETNVLLETWNATAKQVPFEQTYSQLFTDQVQRTPSAIAISDQHTNYSYQALDQRANRLANYLQSLAISTNQVVAILADRSCDFVSAVLGVFKAGAAYLPLDLEHPPRRLAQVLQQSQSRLVLVGEAWQATLAAALSILPSDQRPIIVLLEQAFNPELSSEAPTIQSQASDLAYVIYTSGSTGLPKGAMIEQRGMVNHLYAKIIDLQLTAADRVAQNARQSFDISVWQMLVALLVGAETQIYPDSIARDPEVLLSYAEQQATTILEIVPSLLGAWLTIFPNRANDLPSFAQLRWLLLTGEALPPAACRDWFTWYPTIPLMNAYGPTECSDDVTHYVVREAPAAHVVHMPIGRPVINTRLYILDGLLQPVPIGVIGELYVGGVGVGRGYLNDPERTQAVFAADPFMAGGRWYRTGDLARYRSDGTIEYLGRIDHQVKVRGFRIELGEIEAALAQHQAVHQSIVTATPNAQGQLRLIAYVVSKAADQPAEQATSARLEQWDSVWADTYDQLSAGDHGTINTIGWNDSYTRQPFSAEAMHEWSWVTVRNILAQQPSRILELGCGTGMLLLPLAPYCLSYRGHDIAAEVLAYVQQRLDQQIHDWPHVSLAQFPAHDFSNIAPHSVDTIVINSVAQYFPSIDYLVQVLAAGLEALVAGGRIYLGDIRNLSLNPLLHASIQLFQAPNELAVEQIAQLAQQQHLRDQELVIDPSFFYALQQQYPQISHIELVLKRGRIHNELTRFRYDVVLHVQRPSLDLQPHWFDWQADGLSLSLVRQVLEQSQPDALGIANVPNSRLSEACGLWQALHVAEQPSTAGELKQALQPLALQGIDPEDWYNLHLNGRYRISVSLAQSGELGCYDVLFYATAKLADGGLPQQIQRLASPRKAWSAYANNPLQESQSLTQQFRQHLRQALPDYMQPEAFVLLEQLPLTPNGKVDRRALAALEAPIQTTTYLAPRNPLEQQLASLFEQVLNLNQVGVDQSFFELGGHSLTGTQLIGLIRSECHADLPLRTLFEAPTVGELALRVAAAQTEPSEIAKPTALKRQRQRVNLNTAGFGQIAESNDGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y7</accession>
    <name>A9B7Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3283"/>
    <dbReference type="EnsemblBacteria" id="ABX05920">
        <property type="protein sequence ID" value="ABX05920"/>
        <property type="gene ID" value="Haur_3283"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3283"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108527_0_0_0"/>
    <dbReference type="OMA" id="RIHYRLA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3320-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="133"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="226" mass="25440" checksum="06A9B4C625D7AA9D" modified="2008-01-15" version="1">MELSQKRQFKDALYEQFARISRALANPHRLELLDLLTQGERTVEDLANETALSIANASQHLQTLRAAQLVSVRREGLYAYYRLANASVQALWLSLRQVGESQLADVQAVVQHFLADRSQYQSISISDLYQRIEQQDVVLLDVRPSNEFAVAHLPQARSIPITELSQRLAELAPDQPIVAYCRGPYCLFADEAVATLSQRGFEVYRLDGGIVEWQAHGFALAQETAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B893</accession>
    <name>A9B893_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3810"/>
    <dbReference type="EnsemblBacteria" id="ABX06446">
        <property type="protein sequence ID" value="ABX06446"/>
        <property type="gene ID" value="Haur_3810"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3810"/>
    <dbReference type="eggNOG" id="COG1657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_945848_0_0_0"/>
    <dbReference type="OMA" id="EGFICRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3852-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="29894" checksum="3B3D0AE77F146951" modified="2008-01-15" version="1">MGRLLVVVVTLVLLLLGNLAQSIAAQGDGHQYHAAVVVQYASGAVDARCVGFDQESISGYDALLAAGFNVVAEGSSMGAMVCSIDSVGCDYPNESCACKCQGGDCTYWAYSHLLDGVWQYSKLGAGSYKVRDGAVEGWAWGGGSVERGSTPPVISWGEVCAAQAAPVATEIPATATSEPTAIPATNTLVPATIASQPSSTANPTSEAIATETQFEPSATTKVASPTIAASATTAPTEQATASPSITPTATLTIVSTPTVEASSSGSAIPINYLIFGLILLALAGGGIWKRQSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8C8</accession>
    <name>A9B8C8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltrans_SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3845"/>
    <dbReference type="EnsemblBacteria" id="ABX06481">
        <property type="protein sequence ID" value="ABX06481"/>
        <property type="gene ID" value="Haur_3845"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3845"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051804_1_0_0"/>
    <dbReference type="OMA" id="PEQAVNW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3888-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="76"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="32699" checksum="1507C437C8E91DC3" modified="2008-01-15" version="1">MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYEYQGKGENWRKLKPHPETWMMSYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQPRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKENQTASQLAPDSIRWIIDDALKFVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTYDTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H3</accession>
    <name>A9B8H3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5007</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07637">
        <property type="protein sequence ID" value="ABX07637"/>
        <property type="gene ID" value="Haur_5007"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5007"/>
    <dbReference type="HOGENOM" id="CLU_578436_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5070-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="109"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="128"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="472" mass="51094" checksum="3B50047301E95F60" modified="2008-01-15" version="1">MNELVVIGVLFLAMGLWGGLAIWKMRRELQSLRVLVANAGLQSPPPLHINKPTEQPVIQTPILDPTPLSGAGSALANPPREARILLDELQGKGTDAYRFPLGWYSSFKGATLQTAQFVRDVNHILLTGQSDSGKDNAALGMLLSLALTKTPQQCQFAIVDGKGLDWLAWEKKDHTWLLATDPEHIEQAMMKLTAERQRRRAILADAGVTKWDKYTGKDLPLLVVFISELLLLENAVGKSQLTGWLNAELTAARAFGIRYIIATQTASNFSTQWRSQISLFMAGFQPSPSQDAPNVGLTTNELDALHVVAPSSLPSPNNQAGGVFCVVQGNQALNVRTTLIDDRDLDYLMECLPNRVALAQKSHDELLTSMLAIAHQNGVKALSTHPEALQTATQQSSVTHPSEALPVATHLVPADEQRRILAVAARATSRRAVCREVYNAVGGTGYNNVRLVCDAAGLLMPTPTAMPTASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T5</accession>
    <name>A9B8T5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07749">
        <property type="protein sequence ID" value="ABX07749"/>
        <property type="gene ID" value="Haur_5121"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5121"/>
    <dbReference type="HOGENOM" id="CLU_643680_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5183-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735538" evidence="1">
        <location>
            <begin position="20"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="426" mass="45762" checksum="0F745E278DD26B28" modified="2008-01-15" version="1">MIRRGLVLLMLLVCCRAPAATTAQTPTSTPSAAAWAFDTPRTLGRDSGVIRGLAVALDDHGYAHTSYLRASEFMAEASHSALIVQGVTQAGDRYERRLWQGEPSAGPTAITARSGRIIVAATLAGTVRLWESRDNGVTWNDMAIPVAASVAQLAILSDGRAVLVLLTRTGMQFHLTIATETSAGSGTWQQANPLSTSPSAVLAVWQRDDVRTDQTGLPLLVVAQGKAGGIQLAITQNGTRWQPQTIASATPHALALSAVGDRMVVVHEQYGVRVLWLASSTVHEDWQVTRLATPSSVIVEANPLLHDPQTDMVLLLTTCRFPDRPFGSYRAQLCLSRVRVDELHQASAWERQWAEPWTPIAMAQPHTAQAGAVVVTHGMQAHVAWVGQFIPSDFLHINATQAGFVTTSEAMATTVRIPALARLDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z4</accession>
    <name>A9B8Z4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07808">
        <property type="protein sequence ID" value="ABX07808"/>
        <property type="gene ID" value="Haur_5181"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5181"/>
    <dbReference type="HOGENOM" id="CLU_1893326_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5243-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14864" checksum="AC539208EA09576C" modified="2008-01-15" version="1">MARSGTSRMPIDMLQRTVQIPYRARFRGSLLALFGAPLTSSTDAENAFSYVFSVQNDRGESWIMTAYEGPTGPAFGEFMPATTDEPIRGAEALLALIESTPPADFDAVLEADDYDSRIFYGCRAGDCYWREEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B926</accession>
    <name>A9B926_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07840">
        <property type="protein sequence ID" value="ABX07840"/>
        <property type="gene ID" value="Haur_5213"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5213"/>
    <dbReference type="HOGENOM" id="CLU_2649500_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5275-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="8512" checksum="DA9DA3DBFF89A18D" modified="2008-01-15" version="1">MQKAEALAYVDMIVDDLSNGELFDAVGEDGYLLLREALEVVQLALQGRIFPTVANQRRLMEIINQQLANPADEHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B927</accession>
    <name>A9B927_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07841">
        <property type="protein sequence ID" value="ABX07841"/>
        <property type="gene ID" value="Haur_5214"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5214"/>
    <dbReference type="HOGENOM" id="CLU_2450552_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5276-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="89" mass="9583" checksum="4901527930F58344" modified="2008-01-15" version="1">MADGVLEDAIRVVLATRPVSTIPTWVVGLAAGEGDDTARLCPVGQVLHTRMDAVVLTAPAFERQIRRLRLAHCRAPRTTGVAKDVPQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B978</accession>
    <name>A9B978_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_5265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="10 11">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10 11">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5265"/>
    <dbReference type="EnsemblBacteria" id="ABX07892">
        <property type="protein sequence ID" value="ABX07892"/>
        <property type="gene ID" value="Haur_5265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5265"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_15_0"/>
    <dbReference type="OMA" id="DQGKMSE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5327-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-0614">Plasmid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31311" checksum="9CC8229A98909DAC" modified="2008-01-15" version="1">MVTPSIVHLALINFAPLSLYHLLESQGRYGEAQRLYERALAVREAVLGAEHPDTATSVHNLASVLKRQGRYAEAQRLYERALAVRETVLGAEHPNTAWSVNNLALVLESQGRYAEAQRLFERALAIREAVLGAEHPATATSVNNLAVVLESQGRYAEAQRLYERALAVREAVLGAEHPDTATSVNNLALVLKRQGRYAEAQRLYERALAIYEAVLGAEHPDTATSVNNLAVVLERQGRYGEAQRLYERALAIYEAVLGSEHPDTQIIRANLVSLQAIMKTKGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B986</accession>
    <name>A9B986_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5273"/>
    <dbReference type="EnsemblBacteria" id="ABX07900">
        <property type="protein sequence ID" value="ABX07900"/>
        <property type="gene ID" value="Haur_5273"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5273"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_668551_0_0_0"/>
    <dbReference type="OMA" id="IAEWIFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5335-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="389" mass="46170" checksum="5E700137AACBCF70" modified="2008-01-15" version="1">MFWQFRLLRWALMTPGFSKDDCQGWLEKQPRYAQNATKIANWVCKQSSLRNFSNDLSTTSQVKRDWINQRFNEAWRLLRNPHGQLANPSDTTEVTSEWQEAAATFLIHFYDLFRSESGLPAFFFQRSRNQKYTAQEFLDAFLSQNDRLCVCPVCDSTAYFTILHRKEGLSVYTDIDHYLPKKIYPHLAIHPYNLIPLCHSCNSGVKTAEDPLRPKAREPYRLDEIWLPYRHSGLSTSLILKIISDEHPFNFTPFSLKSDSTSTLNISMLNDLLSRVYHIPERWQIRIDEIGEKLFRRIRDYIRFMNVETDDSSAIIYLDELLYLFDQEESSREPYAIAMMWLLAHLLISPQIKEPFMEEIKEWQQKKIQQTEYMREHGKRIRLTLNNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B990</accession>
    <name>A9B990_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_5277</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5277"/>
    <dbReference type="REBASE" id="16925">
        <property type="entry name" value="M.HauORF5277P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07904">
        <property type="protein sequence ID" value="ABX07904"/>
        <property type="gene ID" value="Haur_5277"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5277"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018284_4_0_0"/>
    <dbReference type="OMA" id="LGAYQYI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5339-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="170"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="571" mass="64841" checksum="2260AF0C9233CAEF" modified="2008-01-15" version="1">MVMDTLPKRSTNETLRSNMWRACDILRRDNNVGGVMQYTEHLAWLLFLRFMDMEEKRRVDLALLNEMPYHPVLHGDLSWDFWASPEALERRSAPELIQFVRGRLLPGLATLTGSSLARTIAGIFSDESTGDQNVVRAVPVCASGYNLKDVLEIINSIHFELDSDLFTISLFYEDLLERMSSENRTAGEFHTPRAVIRFMVELMAPQIGETVYDPAYGSAGFLVQAFLFMQPFARTIEEHTSLHEQTFFGIEKKALSALLGTMNMVLHGVNAPKLLRANTLEESMQGDSGQRYDVVLTNPPFGGTEGAHIQQNFAVKANATELLFLQHIIKKLKRTPNARAAIVVPEGTLFRSGAFAEVKQDLLQQFHLFAVFSLPPGTFAPYSDVKTAILFLKRPDSLLIANPLAREETWFYELPLPEGLKKFSKGSRISDSHFDEARHLWQVWSDYLSGNAERPFVYAADLRPHQTSNEPTPIQETFFANKQTSLQLSSINNRQFEPVFARNINAWIETYNDIASRGFDLSARNPHRVEQESRESAFVLTARLLERSRELHSMIQSLHAKLSQGREEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU97</accession>
    <name>A9AU97_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dak phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0365"/>
    <dbReference type="EnsemblBacteria" id="ABX03016">
        <property type="protein sequence ID" value="ABX03016"/>
        <property type="gene ID" value="Haur_0365"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0365"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017496_1_0_0"/>
    <dbReference type="OMA" id="TRTIPQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-368-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019986">
        <property type="entry name" value="DAK2_dom-cont_prot_YloV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13684">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03599">
        <property type="entry name" value="YloV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="12"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="545" mass="58501" checksum="DF6905036CAA0AA1" modified="2008-01-15" version="1">MDSAPKNQIDGTRLLAVFRAAAAWFSQNVATVNALNVFPVPDGDTGTNMNLTLTAALKDVQNDASVAVVAERVYRGALMGARGNSGVILSQILRGLSQGMVGQQVCTPEILVTALEQAATTAYKAVIKPVEGTMLTVIRETSEAARAGFQPEMNWHEVLDLIVKGARVSVDNTPNLMKMLRDAGVVDAGGEGLYLLFEGARAFARGEQLEQRVAPVDQLAMAFDDIHSDDDFGYCTNFMIQGENIPYEDVRNTIAEMGTSVVAVGDERLVKVHLHTLRPGDALNYAVQWGSLGAIEITNMDKQRSDLHAAQAQQASQPARVKLDEPVSDVGVVAVAPGQGFRVLFESLNVGEVVTGGQTMNPSIQDLVTAIDKLPQPEVIVLPNNSNVILAAQQAQQVTNKVVHVIPTKTVPQGMAAMFAFNYAVGASDNVQAMSRAIKDITTAEITTAVRDATVNDVEVRDGQTIGLLNGALVESGDQPDEVIDRILARMDLDDHEIVTIYYGEQCSAEQAEALAHKINATYPALDVEVQNGGQPFYDYILSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC6</accession>
    <name>A9AUC6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transmembrane anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0394"/>
    <dbReference type="EnsemblBacteria" id="ABX03045">
        <property type="protein sequence ID" value="ABX03045"/>
        <property type="gene ID" value="Haur_0394"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0394"/>
    <dbReference type="eggNOG" id="COG5662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1132939_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-397-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="30867" checksum="3C4227E6C76E2F0B" modified="2008-01-15" version="1">MTPISEQQQELLSAALDGQLSAAEQAQLDQQLEHDHGLAVEFAELRSMQALLQELPPVRPPRSFTLDPAIHAPKRSFWLGGWIRWVGVVGAFALMLTVGLQLTNQSGQSMTMAPVADMANPEAANGVSDRMAIENNNTSAEAPPMGSGSGSGPADPSQPTTAEDTMAVLDQTPEPMVGGAAPAMIEGYPTPMAYSSIPISDTAGMARMSAEQATALAGSPLNNPLIDQNNPSSPGTLDLEQPVLKEQTPTAQPVPIAMAESEPSLLLWFSIALVLGVGLASAMVYWLKSFKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI4</accession>
    <name>A9AUI4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1868"/>
    <dbReference type="EnsemblBacteria" id="ABX04511">
        <property type="protein sequence ID" value="ABX04511"/>
        <property type="gene ID" value="Haur_1868"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1868"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009398_1_1_0"/>
    <dbReference type="OMA" id="HENLIAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1897-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="213"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121167" checksum="42DD0CDDE5528F8E" modified="2008-01-15" version="1">MTTHKQLGWGATLPLAMRSMHVQQCCDQPLNAANQRRFDRWRAQTPFQDSDWFSQRLAQNQLTPEQLQQFLQTPAQQFEADQAAPDWVALFEMAYRTPLSERLPYSAKLLQHPMHGLLYLVEPLLAYAVQHLQQQLSAVQPRQAFLQPAQWVTLWFEALAQRCLWMISRVTVLELHIARVQAQLNGTTPEERYQDFVQQLQDRQRAQQLLQAYPVLIQQLCLTIQRWQTNSMTIFERLNHDWPALQQLFPVLQQTDGLIGIQTGAGDVHAGGQSVVILSFSNAKLVYKPRSLAIDQAFQELLHWINQHSSMLPLRLLKILDRHDYGWSEWVDHAMLSDSAAIERFYQRQGIYLALLYVLNASDFHHENIIAAGEDPMFIDLESLCGPQVHSDNQLENEFMANQVLTNSVLRVSLLPERFQARAGKTGIDISGLGTRDGQTSMDTMPLWVEAGTDSIRMTKQTVSLSGSQHSPIATVSAEQIGSYLNCVVSGFEAMYDFLLAHRSELLADSSPLANLYRCKIRVIARHTAYYTKIYQESFHPDVLRDALDRDWLFDRLWFEVKYNQRLVELIPYEHRDLWQGDIPLFTTVVDSCDLWSSDGQRIADYLPRSGKTMVLERLHQLSSNDLANQVRLISFSFATMSASLHNSYRSDERYLLPTSIQPSHADWLLAACGVGDELLATALQNDHSITWIGLTQQLELQMVGLDFYDGLPGIIYFLAYLGAISGVERYTQAAERALQTLELLLEQHQATLTDVGAFVGWGGLSYLYWHLSSLWQQPALLEKAKTWLAQIPSLLANDSTFDLMAGAAGSLLVGLRLYAQQPSAELYTSLVACGEHLLANSQAEELGRSWQTITDAEQPALGGLAHGTAGIAWALIELAQLTNDQRYRESGLQALAYDNSLFVADQQNWRDIRTAKTKGNQQSDDLVICMAAWCHGASGIGISRLAMLRCLDDPTINHDLQQALATTLTQGFGMNHSLCHGDFGNLALIQAAAKHYADQQLADQAQTIASELFASIQRDGYRCGVQYGAQPPGLMTGIAGIGYGLLQQAAPNVVPLVTFLESPAIFPTNEPLLEVISRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK5</accession>
    <name>A9AUK5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1889"/>
    <dbReference type="EnsemblBacteria" id="ABX04532">
        <property type="protein sequence ID" value="ABX04532"/>
        <property type="gene ID" value="Haur_1889"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1889"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_0_1_0"/>
    <dbReference type="OMA" id="RFLMPPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1918-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="44511" checksum="A985144FD6BDB2DC" modified="2008-01-15" version="1">MITKALTIALAYLQTITRNRSFLFQMIVIPLLLTFIIGQAIGGGADELPDPNTKWRMVIANEDTGSLATQLVEYLQSTPRLEVQLVDRAAANAAVASADTGVIGALIIPADFSTKFASDQAVTLDYASFVASVESQYLEQSVDTALGQLSHSLNAADVSADVADELGLFATSDNPTTAQQTYRDDAVERALTAWETNPPVVVEAEQASFQQSDDGVPRGLNQTSPGLLVMFAFFFTIGGGSSLIQERTIGTLQRLMVMPMRKSTILFGKLLGIYIGCLIQIGILVLAGAFLFNVDWGNSPIAMLVFIPVFALNATSLSIMLAALVQTDAQLNSVSTIVVMALAALGGAWWPIEIVPEWMQQLGHALPSAWAMDGFNDIITRGLGLEAVLFEIGVLMAFTVGFFIIGIWRFRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ9</accession>
    <name>A9AUQ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1943"/>
    <dbReference type="EnsemblBacteria" id="ABX04586">
        <property type="protein sequence ID" value="ABX04586"/>
        <property type="gene ID" value="Haur_1943"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1943"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_326732_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1972-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="881" mass="99227" checksum="240C15224AB893AC" modified="2008-01-15" version="1">MAHVLNPILRTVLNQFDQPAQLGNIQPLATPAFLGQWYDLFGAHPSERQRGQIIQLVVVYALLGDTHIRPEESHDLAELLEQLRAGNRDQRLIYWRFLHEHKLPVNVLIDQLGLAKATFHRDMKDRLPLILDQATDCLLSILQPALQLERPPVPSHLYGRSQWLAEAQALLKQQRQLCIIGAPGVGKSASAATLAAAWQGPVFWLSLLPDLNDQIESCLPLIGAFLQHHGAYNLAQHLAIEGGKLNSNVALGLIRRDCASLPAAPLFCLDQGEVMLSQPQHSALHSFWRALAAIPNLHLLIVGNQVFSNDLPTLTLEPLDSAALKAWFNASTAIQPDYPWEQFLALIAGNAHLMRIVMVLMQQEPSLAAICAMLAAHPSVGYLIERIISMLSPNAQQLLTVLASFQQPVPRSLWPTKDLQQLEHFELLQTGYHDTLELWPLLRKHFWQQLSAEQRQPLNEHAAQVHAMLGQWTLAAEHAIAAGAYSQAIMWWFPQRHNEIRAGYFGRMLRMLQLIPLDQIPAREAQTLAIGQAELARFTGNYEQARASLAAVSYTGSDSIRAYIRQLEGDLWEAQGYIEQAMSSYERAITILDTNQQHQEAILHVKRGLMHLNHERDFAAAHLAATKTHFIAALLSAEVADEEGNYDLALQGYQTALDHACTLNDQALQARAHASLAIVHARHEHSEAIEHFDFAIRYYRSIGNDVRVARNQSNLAYFLVEINQPHEAIKLAEQAYSFFKQINSRFWVSLNAMTLADAHLSLDQYPTAEQYAQEVLHYEETGHVPFGVYILGRVATLKHEFELAERYLQQAIQLSQAIQDRFIEARVWRDLTKLLHQTQRHGEAKQAIKQACDLYQQLGLSKELDRTLQLAQGYNLQLIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR0</accession>
    <name>A9AUR0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1944"/>
    <dbReference type="EnsemblBacteria" id="ABX04587">
        <property type="protein sequence ID" value="ABX04587"/>
        <property type="gene ID" value="Haur_1944"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1944"/>
    <dbReference type="HOGENOM" id="CLU_979242_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1973-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732162" evidence="2">
        <location>
            <begin position="28"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31165" checksum="58C0C96D75247BF1" modified="2008-01-15" version="1">MRLVLIVTVLICGLGSFWFNQPNQAKADTPAPPPGCGLAGVDLSTPNTWMAVWDFETADGCLVRLGTPEIPSQDPPILLMSTIECSVNGNVDFSPADYARFQGAGYLSCELDLPNDLLQSYPDFWSYVQVQFSTNGNHPLLYHPDARMNVSVNGLYGNLQWQYRHTTDLFESNMIRRFRLTSDTRLAVGQCSGSVQTCPVTQSAPYAGYATIHGDTNYADSSQTMIKFRTTATTLLIGYNPDTNEYLNGKLGMLIIDPYGKDPEPTVINPDPTPTATPTPPIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU6</accession>
    <name>A9AUU6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3900"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06534">
        <property type="protein sequence ID" value="ABX06534"/>
        <property type="gene ID" value="Haur_3900"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3900"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_0"/>
    <dbReference type="OMA" id="DMICAFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3942-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="29132" checksum="137C16F82E99EA70" modified="2008-01-15" version="1">MTSERPSISVFFPAYNDAGTIGSLVITAFHVLPELTDDYEVIVVNDGSSDYTAQVLDDLATKYPRFRPIHHPKNRGYGGALRTGFASATKDLVFYTDGDAQYDPNELRDLYQVLTPEVDIVNGYKIARSDPLHRKIIGRIYHHGVKFLFGFKLRDVDCDFRLIRRKVFDVVNLESDSGTICLELVKKLQDAGFNFAEVPVHHYHRTYGKSQFFNFPRLWRTLIQLLQLWWKLVILGKHLKEQAARQRALGRDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW1</accession>
    <name>A9AUW1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="4" type="ordered locus">Haur_3915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3915"/>
    <dbReference type="EnsemblBacteria" id="ABX06549">
        <property type="protein sequence ID" value="ABX06549"/>
        <property type="gene ID" value="Haur_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3915"/>
    <dbReference type="eggNOG" id="COG1054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038878_0_0_0"/>
    <dbReference type="OMA" id="CDTHTNC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3957-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="122"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="29332" checksum="F12616555E5342E8" modified="2008-01-15" version="1">MDILVIAFYKFVDLPDFAAKREPLRDFCNQRGIKGTILLAHEGINSTVAGPEPAMRELLEFLRSDSRLADLVWKESWTNEIPFQRMKVRLKKEIVTLGMPEINPNDGVGTYVDAEQWNALINDPEVVVIDTRNDYEVEVGTFPHALNPKTDSFREFPAFVEQNLDPQQHPKVAMFCTGGIRCEKATAYMLRKGFQAVYHLEGGILKYLETVEPSANQWQGECYVFDQRVAVDEQLKPGHYDLDQPTGLPRKREEASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV21</accession>
    <name>A9AV21_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3977"/>
    <dbReference type="EnsemblBacteria" id="ABX06609">
        <property type="protein sequence ID" value="ABX06609"/>
        <property type="gene ID" value="Haur_3977"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3977"/>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062599_0_0_0"/>
    <dbReference type="OMA" id="PHISQGV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4019-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="31000" checksum="694E57F170C6BBC6" modified="2008-01-15" version="1">MITLDCKLAARTPERQRTTVDVGGVRIGAEEIVVIAGPCSVENEEQILATAQHVRAAGAHMLRGGAYKPRTSPYAFRGLGEEGLQLLAKAREATDLPVVTEVMTPADVGLVAEYADMLQIGARNMQNFHLLEAVGRIQKPVLLKRGMSGTIQEWLLAAEYILNCGNPNVVLCERGIRTFEPSLRNTLDLGALAFAKELSHLPVIADPSHGVGRRSLVGPLALASLAAGADGLILEVHPHPERSVSDSQQTVDCAEFADIMLRADAVASAVGRRLHLPAITPAYAEAADVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV68</accession>
    <name>A9AV68_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0495"/>
    <dbReference type="EnsemblBacteria" id="ABX03146">
        <property type="protein sequence ID" value="ABX03146"/>
        <property type="gene ID" value="Haur_0495"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0495"/>
    <dbReference type="eggNOG" id="COG1547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2081589_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-501-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005500">
        <property type="entry name" value="DUF309"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023203">
        <property type="entry name" value="TTHA0068_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03745">
        <property type="entry name" value="DUF309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140663">
        <property type="entry name" value="SSF140663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="117" mass="13725" checksum="B357EC1B514E1BEA" modified="2008-01-15" version="1">MNEQEHWQGFITAFNEERFVDGVLQLEELWFPSRNDLYRGLIRLSVALNQLRLGIVDSPRQLLASAYDMLAPFETNQHNLDIRRIREYIQDCASLIPADLRTGQGRIDWDLVPRIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV93</accession>
    <name>A9AV93_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0522"/>
    <dbReference type="EnsemblBacteria" id="ABX03171">
        <property type="protein sequence ID" value="ABX03171"/>
        <property type="gene ID" value="Haur_0522"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0522"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_0"/>
    <dbReference type="OMA" id="ICPSIAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-530-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="8"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="273"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="40860" checksum="4086C159B13B7C83" modified="2008-01-15" version="1">MSNEREPVLLSAARTPIGKFGGSLADLTAPQLGAIAIKAALERAGINGDVVDEVIMGNVVGAGLGQAPARQAALGAGVPDSVSALTINKVCGSGLKAVMLAASMIKAGDAELIVAGGMENMSRAPYLLPQARFGYRLGNGEIQDAVVHDGLWCAVEHHHMGNSAEWVADACNVSREMQDEFAYNSHRKAAAAIARGAFKNEIVPVELKSRKGTTIFDTDEPVRADSTVEALAKLKPAFKADGSVTAGNAPGITDGASALVVASMAKAQQLGAKPLARITGYAQAGVKPLEIFTAPAFAVRRLLEVTNTSLADYDLYEFNEAFAAQALANGHDLKIDWDRLNVNGGAVALGHPIGASGARVLTTLVYALQERGGKRGLATLCLGGGEAVALAIELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA8</accession>
    <name>A9AVA8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
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            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0538"/>
    <dbReference type="EnsemblBacteria" id="ABX03186">
        <property type="protein sequence ID" value="ABX03186"/>
        <property type="gene ID" value="Haur_0538"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0538"/>
    <dbReference type="eggNOG" id="ENOG5032X0G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085624_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-547-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032787">
        <property type="entry name" value="Prok-E2_D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14460">
        <property type="entry name" value="Prok-E2_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="23560" checksum="036E8876B4C91839" modified="2008-01-15" version="1">MFDKSPKLQLDFFDNAVIMTRREPSGWSSYPVDVSEVAKVLSGIPQSSGLLPQNTLGYGSYKGSSFYCMYIPPKSITIELANNDRLTIPIPPLVWRGWKQNYQIWALATEAYPLASTPLFMAPFPNVYPNAMICWGDSDDRLPAGPSTMQAMLDLFLIGSRFNTHLVGGKSMRSSGNIINLYHRIKGKAMYPLHDLCATDLVLENVLEGGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI6</accession>
    <name>A9AVI6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2034"/>
    <dbReference type="EnsemblBacteria" id="ABX04677">
        <property type="protein sequence ID" value="ABX04677"/>
        <property type="gene ID" value="Haur_2034"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2034"/>
    <dbReference type="HOGENOM" id="CLU_2734521_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2063-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="71" mass="7898" checksum="E4964F02658A1C8B" modified="2008-01-15" version="1">MSLVAILEQVQTLSIQERKDLVKFLVDSLDVPPRQPLLRLADMAGFAASLATGEDAQTYVDGLRDAWERPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVJ0</accession>
    <name>A9AVJ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2038"/>
    <dbReference type="EnsemblBacteria" id="ABX04681">
        <property type="protein sequence ID" value="ABX04681"/>
        <property type="gene ID" value="Haur_2038"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2038"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1388565_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2067-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="22495" checksum="041C073079A53613" modified="2008-01-15" version="1">MATIRNFEQSIAIVQSLEEESQSIALHRIAIALTKIGDIDQALIFTQFILDEFIRVNTWIRMVAITTENKNHQKAREVLYSTIEQVSLMNTTDDVLSRLANSASLLGQLDQAFAIAQSISDTAQRVKILATLIQTYDPTPERTLSIIQSEWYQVKHDSRLWDFLPLAIPLLDQYPWLGIAILENEKWVKQQQVWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN6</accession>
    <name>A9AVN6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4004"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06636">
        <property type="protein sequence ID" value="ABX06636"/>
        <property type="gene ID" value="Haur_4004"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4004"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_8_1_0"/>
    <dbReference type="OMA" id="RYEGFPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4046-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13477">
        <property type="entry name" value="Glyco_trans_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="189"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="398" mass="43960" checksum="FC0579DF721B68FF" modified="2008-01-15" version="1">MNQPLVLHIATADMGLRFLLLEQMQAIHHAGYQVRGVASDGPYRAEVEAAGIPVDVIKMPRAITPNRDLLALTQLVRLFRELKPTIVHTHNPKPGLLGQLAARIAGVPIIINTIHGFYFHEHSSANQRRFYIAMEKIAARCSHAILSQNREDLNAALALKIARPEQISFLGNGINLQVFDRRAVSQADIQAARQELGIPADAQVIGAVGRLVAEKGYHELFQACQQLMATRPNLHLLVVGPEEPNKADGLTAATAAKYGIAERTHFAGLRRDMPVLYRLMDVLAHPSYREGFPRAPMEATAMGVPVVASDIRGCRETVVHSLNGMLVPVRDVAALAHSLGRMIDDRVLREAFARLTRRVAQREFDQQRVFDRVLLTYAKQLQAHGMAVPEPIQSQAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVP7</accession>
    <name>A9AVP7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4015"/>
    <dbReference type="EnsemblBacteria" id="ABX06647">
        <property type="protein sequence ID" value="ABX06647"/>
        <property type="gene ID" value="Haur_4015"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4015"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079026_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4057-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="34539" checksum="BBE2674D1EFFF85B" modified="2008-01-15" version="1">MSDRTPPTEVLEFENDLEPDPEPEEVPSAIIQEDEAIAPQGMTFQALVFGVAIILIIFLVLLLASGNNINLFNLFGSDSNAQPTLQPLLNSVQTQSNRSLDVEAAVLEGQRFYGVDGLNALPSYAAEIDPLFLPYWVKNGGERIFGRPISGLLEENGRQFQWFERARLEWWPEHQATKYEVQPGRVGVEFTQNRDFPNQQFFANRPGLRYSEATQQGLRGAFLEFWEANGGIDLLGWPISEELQEVLPEDRTVHTVQYFERGRLELHPNDPNQMVKIGLLGRALYFQDSQPNYIEPVAPTAVPVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVP9</accession>
    <name>A9AVP9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxypyruvate reductase</fullName>
            <ecNumber evidence="3">1.1.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.81" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4017"/>
    <dbReference type="EnsemblBacteria" id="ABX06649">
        <property type="protein sequence ID" value="ABX06649"/>
        <property type="gene ID" value="Haur_4017"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4017"/>
    <dbReference type="eggNOG" id="COG2379">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032279_1_1_0"/>
    <dbReference type="OMA" id="GKAAWRM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4059-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037035">
        <property type="entry name" value="GK-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038614">
        <property type="entry name" value="GK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007835">
        <property type="entry name" value="MOFRL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025286">
        <property type="entry name" value="MOFRL_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039760">
        <property type="entry name" value="MOFRL_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12227">
        <property type="entry name" value="PTHR12227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13660">
        <property type="entry name" value="DUF4147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05161">
        <property type="entry name" value="MOFRL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4147" evidence="2">
        <location>
            <begin position="11"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="MOFRL" evidence="1">
        <location>
            <begin position="328"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="442" mass="46212" checksum="4D4B8F1626632B3E" modified="2008-01-15" version="1">MDAAAIAKFSEQLIATAIASVDPQRAVLQALDWDCTRLSCGDWQWAGTGRIIVLGAGKAGAPMAAALESILGERIDRGLVVVKDAHCGDFALKRIQLLEASHPSPDQRGLNAAQQCEIWLQQAQADDLVIALISGGASALLPAPSGAMSLADLQTLTQLLLACGAPIEQINTIRKHCDRLKGGQFAALAQPASLLSLVISDVVGSPLTIIASGLSVPDPASFAEAWAILEQYGLIDRLPLSIRDYLQLGMRGAVPAHPDGSEPWWANVHTTIIARNEIAQTAIKQLAEAQGWQVIHDQQPITGEAQVVGQQVGQRLCQLAQSVQQPTLYLAGGETTVNLAGILPHSQGGRNAELALAAALALDGCPNCQIIALATDGGDGSSPAAGAIANGQSIAQARKLGLDPHQALAIHDSYNVWRALGSAIEIGPTLTNVNDLLIGLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU3</accession>
    <name>A9AVU3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4061"/>
    <dbReference type="EnsemblBacteria" id="ABX06693">
        <property type="protein sequence ID" value="ABX06693"/>
        <property type="gene ID" value="Haur_4061"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4061"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014916_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4104-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="534"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="653"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="885" mass="97212" checksum="4DD79D55938719A0" modified="2008-01-15" version="1">MGRNSSFRIWLTRIRPLAWALACFALVLFGYTFTTTIPTDRLTVIASILGVAALALPWLFNPEGDWRELRTLGILALPLSVAILSEGYNTALWSVLLIPAIAIPQMLPPRWAFSAIALMVIAWAVSNVLVPAVAVETVAIEVGLRSLGFVLVAIAVWLAARPRFDYPAMLPEAPIRRATRAAERLRGSLSPEETLEELASAAKACGPFIFASASTVDWRARVLRMAVAIGGSGRTLGATEMLSIPWDEITVLLRDDRRIGDNAYLADSLPFRDIAGEHYMLVPVRTATGEICGLLTVGDDDPKARKRLTETAPLLELLASQAAAVLENAALQNTLAQRIEATTAEMGRTAEDAMRARTRAESMYQIVRALSGTLEPQPLLDQALLLIAQATQAERGGIMLIDHKNGRLAFSTNLDRNITRTEAISLERGQGLAGWVVEHRAPVIIPNTAEDSRWMVRTDYDKKGRSALAVPMEQDGRVAGVIVLINSRINHFTQEHIQFVQVIGDQVMTMLSNVQLYRATTEQARRLSQALEQREEEVSRSLAIVRSIGDGVVVGDRVGRIRLINPAAEQLLNIEAAEWLGKPLMSLPGAPESEPRLTEKQTYQQFELSGRMIRASSTPVFTSQSEWLGSVVVYHDITASELADRMKTEFVATASHELRTPLTSISGYIDLLMLNTLGPLTEQQRQFLSVVKNNIERLNAILNDLLDVSRIESGKVRLQRKPINLDELIQSTVMSIHQQWSGKQISLALDVPDDLPPMIADPERMRQIVTNLISNAYKYTRDGGRIDVVVSNGGDSVTLAVKDSGVGIAADDQKHIFTRFFRSENPLKEQAGGTGLGLNITKSLVELHGGKIWFDSEEGRGTTFNVQLPVGGDSDWTPASWLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW82</accession>
    <name>A9AW82_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2092"/>
    <dbReference type="EnsemblBacteria" id="ABX04732">
        <property type="protein sequence ID" value="ABX04732"/>
        <property type="gene ID" value="Haur_2092"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2092"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_11_4_0"/>
    <dbReference type="OMA" id="RIAYIAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2120-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="69"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1568"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1661" mass="185337" checksum="1834955C823F2476" modified="2008-01-15" version="1">MPTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAAQHEQQTQTAPRNPLEQQLAAIWQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIRLTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLTPIQRWLLADPTDPSQFNQALFLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNLNPTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRIIIQDLAHALQNQPLTKPAVGFAQWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGHNDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAALTQTITAWSGHADVVLQLEGHGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLRSADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVLAGQLQIEWSYSQHLHSAATIERLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQLDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQMQFEITGQLNHAAFSAAWNRTIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGFEPTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAPEIPYQRYIQWLAQHNDQQATAFWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSAITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFGTTTAGRPTDLAGVEQIVGMFVNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVFENYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRMLDYLQQGLAAMLAQPKARLGQLNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQPTSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIGLRAERNPQFVAALLAILQLGAVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRDLAYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLTALVVGARMQIIDDQTMRDPQALLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAALRWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDVTLWPIASAVELPQNAIPIGRPVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMYRTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQARLIAYLVAKAKPVSDQLLRDFVQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQTAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELGGHSLLATRLVSQIRQYWQLDLPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWM2</accession>
    <name>A9AWM2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4149"/>
    <dbReference type="EnsemblBacteria" id="ABX06781">
        <property type="protein sequence ID" value="ABX06781"/>
        <property type="gene ID" value="Haur_4149"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4149"/>
    <dbReference type="HOGENOM" id="CLU_042538_4_2_0"/>
    <dbReference type="OMA" id="AMEHWVI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4195-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="36271" checksum="57D19B098FF7B4B4" modified="2008-01-15" version="1">MFVNIQLPFTSKLNPHLEAVYAEHSQWLSQSPHSAKSQWGFYQRLRLPQLLARVYPHACSERLRLILDWGGWLFFQDQWFRSLAGQPELVASLANDLINVFNGATPLYPQKPLVVMFADWSQRMAGLTSNQWRERFGQMLSTYLHDWVYDVYCNAYQPTINNQLAVELHQRIGAATSSLDFVDFAQAELLPPSVKQDPTFQSLSEITNNVVCWMHDIASLERDLTLAEPQNIAVLVKQREHCTWSRAIERVEQMCYGEVAAFERIVAERPHYGEFELVVSDYIENLRAWMQGTIDWLRLDLVVANEPANRLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN3</accession>
    <name>A9AWN3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4160"/>
    <dbReference type="EnsemblBacteria" id="ABX06792">
        <property type="protein sequence ID" value="ABX06792"/>
        <property type="gene ID" value="Haur_4160"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4160"/>
    <dbReference type="eggNOG" id="COG1700">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_492479_0_0_0"/>
    <dbReference type="OMA" id="LYERWCV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4206-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018633">
        <property type="entry name" value="DUF2357"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007505">
        <property type="entry name" value="PDDEXK_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09823">
        <property type="entry name" value="DUF2357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04411">
        <property type="entry name" value="PDDEXK_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2357" evidence="1">
        <location>
            <begin position="80"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="516" mass="58302" checksum="AD0F693E6F50D6B0" modified="2008-01-15" version="1">MAELIPLTINGIDSQATVHVTASAWNEWAVVNMACPAQTNVRNAQLSIGADNLGVPQVSPFDPTWRWSWLPRGQAGTVYGRLQIEWADGEIQQQQFQFELQPHLLDRELWRALLNDLSSLARSLALRIASPSFAQAVLVPLLPDDPSPFLEALSLINQSSQQASQIVRSLQRQAKSTLERQPRTTDLGTAQQFKLDQLAQPSERYHVLEPYGLVPEQVQAEHAQASFDLPEHRWLIGLIQQIERRLRNLRRLAREQRQLDLTSIQATIEQRLTALRQLRQAAPLAGLKARQQPVQSQLINRDARYRPIRQLARSLHEQPLLTLEVGSLALPLADVPTLYEQWCALAVAQVLAELGQVEAQHLLIDNPQRERWVLELNSATPLLSVRIGSQLWHLRYQARFSAQPDSDGFYSLDRYLRIPDLVLQTATANAKQVLVLDAKYRRAPDQRVPQSALDDVYAYRGSLGYNGQPCVLAAAILYPQANTLEEFGSIAAIGLIPNQLNQLKTWLERWLNQLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP0</accession>
    <name>A9AWP0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4167"/>
    <dbReference type="EnsemblBacteria" id="ABX06799">
        <property type="protein sequence ID" value="ABX06799"/>
        <property type="gene ID" value="Haur_4167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4167"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035299_0_0_0"/>
    <dbReference type="OMA" id="MADSITY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4213-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="570" mass="61961" checksum="5B5F3502851FB3FD" modified="2008-01-15" version="1">MAISEGRSIEIDARWENLAALTDYTTEIETEFALTSEQAFVLGLVIEEIVTNIIKYSYAEQGGPLQLHSTLENGELAIRILDRGQPFNPDDADPPDLFASIHDRQVGGLGVFLVREMADSITYHHDDASGWNTLIVTKKASTEASIAPLVEFLEQLPLFHEVDQATIQNLVQSAEHVRLAPGETLFSEGDSGDDCYIVMAGDVDVIKALATETILLERCRPGAILGEMALIDNSPRAASVRARTAATLLRITEAEFVTLMHANPTTAMALLRGGTTRLRQANAQMLGGLEKKNLELASAYEELKSAQQELLRLERIERELAIARDIQRFFLPPNIPQPEGWQIVAFNQGALEVGGDFYDVIKLGGNKIGLVVADACGKGVPAALFVALTRSLLHSNAQSLAARPEIATDPLALLTAAITMTNNYISREHGASNMFTTLFFAAFDPQTGELAYVNAGHNPPIIINRTSRTLRYLEGTGLPLGIMEDLPYKAKSTILAADEYFLGFTDGATEAFNLAGEVFDDAALTNVLKNGDFHDAQSLLDSVWRAIESFVGEAEQADDITLLTVSRNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX54</accession>
    <name>A9AX54_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2222"/>
    <dbReference type="EnsemblBacteria" id="ABX04862">
        <property type="protein sequence ID" value="ABX04862"/>
        <property type="gene ID" value="Haur_2222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2222"/>
    <dbReference type="HOGENOM" id="CLU_2273490_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2250-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="102" mass="11888" checksum="2844F38020715D6C" modified="2008-01-15" version="1">MTISIDIEFIMIPAHLGGRTHPLFETMWINFRWQRYPAWLWSIRIMNLEYDPATRIGYAQQCALIVEEPCTESWLQPGQLLELCEGPTVVAIGKIVEPRERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX72</accession>
    <name>A9AX72_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2240"/>
    <dbReference type="EnsemblBacteria" id="ABX04880">
        <property type="protein sequence ID" value="ABX04880"/>
        <property type="gene ID" value="Haur_2240"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2240"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_2_0"/>
    <dbReference type="OMA" id="PGYEMRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2268-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="32051" checksum="E0D0823A6C827FE0" modified="2008-01-15" version="1">MPRWREIVQVDAFAHVPFTGNSAAVLLDTAGLDPVVMQRLAREMNVSETAFVLPSSQADLQLRWFTPTVEVPLCGHATVAACHALAERGHLVIPGRYQIETASGILAVELQESKTSACKVWLDIPVPEFEPLELQIVALTAALGLDEADIRSDIPPTRGGNYGYIGCHNLANLLAIKPNMNDVRFLCQSHELTALVLYCLEGLDAESAVHLRFFGPVIGIDEDPVTGSAQGPLGALLVGVGAIAQADGSNLVQYRAEQGDAMGRPGRLEVAVQFDQEAQIISSRIGGEALTILRGHVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ7</accession>
    <name>A9AXJ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Single-stranded nucleic acid binding R3H domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0763</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0763"/>
    <dbReference type="EnsemblBacteria" id="ABX03411">
        <property type="protein sequence ID" value="ABX03411"/>
        <property type="gene ID" value="Haur_0763"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0763"/>
    <dbReference type="eggNOG" id="COG1847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042512_0_1_0"/>
    <dbReference type="OMA" id="RRVQKWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-775-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02644">
        <property type="entry name" value="R3H_jag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038247">
        <property type="entry name" value="Jag_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034079">
        <property type="entry name" value="R3H_KhpB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="R3H" evidence="5">
        <location>
            <begin position="174"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="240" mass="27120" checksum="5C44AFA841217BAD" modified="2008-01-15" version="1">MALQKVEVRAASVAEAVAQALAQLGKDEDEALIEVLAQTADSALVRVSVDDDEDELLAEYGDEDDEEQPKRRRRRVASTDEQTVALARQLLEALLTRMNIDAFVTPVVQKAKGSDDEEDTLTLHIEGVDEETTGLMIGRRGETLRSLQYLLNVLIHRQTGRWSQVVIDIGQYRQRRQDSLEGLALRMAERVRQSGRPMPLEPMSSFERRIIHMALRDDPSVYTESAGEGEHRKIVIYPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK6</accession>
    <name>A9AXK6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0772"/>
    <dbReference type="EnsemblBacteria" id="ABX03420">
        <property type="protein sequence ID" value="ABX03420"/>
        <property type="gene ID" value="Haur_0772"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0772"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-784-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="101"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="38264" checksum="14ACD199ABA51240" modified="2008-01-15" version="1">MFFVFFTDYKKSLISAFVNTAFILYIAYQPSLQWIAHTLPILSFFIIITAVAWIYQRTLDNSMISLQAARQQLMQDTLIRQELAIARNLQQELYPKPQHYSECLDIGASVQPALETSGDLYDLIRLNDDEIAIIVGDATGKSVAAAMVMAMTRSIIRSEARRSRNPGHVLRHVNAILHADDAVNQMMTVWYGVLNLRHHQLRFANAGHPFPLLRRNGVVQELEAFGTPLRSIRNFPYAEQTIQLQANDRLVVYTDGVIETMNEDRELYSFDRWCAAVRDIEAENTAGLIDAYCAAVDEFRGAARQADDLTLVVVDIIKDPSEVVTLPVADTTAVVVTADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT2</accession>
    <name>A9AXT2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2258"/>
    <dbReference type="EnsemblBacteria" id="ABX04898">
        <property type="protein sequence ID" value="ABX04898"/>
        <property type="gene ID" value="Haur_2258"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2258"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021408_1_0_0"/>
    <dbReference type="OMA" id="LEAWTAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2286-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732227" evidence="1">
        <location>
            <begin position="29"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="530" mass="54916" checksum="01B9426039B661DA" modified="2008-01-15" version="1">MLRRKKILLSGLIMLGLGLVWDSRPVAADSVVVGTGTPASCNEAAFDAGLAQLFPGEQAPGGTLTFNCGPNPHTIVLTSQKFLHDGSVIDGGGKITLSGGNTTRIFWVSQQARVEIQRIILTNGNAQHSGAIFAEPNWSGEFTNLALNQVTIKHSQATTFGGGIGAQHTNLSLIDSLIEANRSSGSGGGVSFNTGNLTIRNSKFSTNKAETEGAGLEAWTANLDISQTNFELNELQGREHTDFGGGLVIQQSYGVFQGGRIWSNIAGQGGGIYLRGGSTIEFNASKIADNVAFNEGAGGYITANSSLTFKNGIIDQNLSAVAGGGIANQGGLLIERSTLTNNEALQSDGGALDNTGVAVLRYSTLAKNKAQRGAGLNNRPNSTLVIDRVTMTANNAEIAGGGIYHAGTLFTVDNSILTYNNAPAGAQCGYASQVPSMSFSMWSDGSCGTQTIDGNKPFTGPSLRPLGWYGGPTPTYLPLSHSASTDAGSCSSSAVTDQRGLAGFVGAACDMGAVESGSLWYQVALPMTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT6</accession>
    <name>A9AXT6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2262"/>
    <dbReference type="EnsemblBacteria" id="ABX04902">
        <property type="protein sequence ID" value="ABX04902"/>
        <property type="gene ID" value="Haur_2262"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2262"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="DNVWGYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2290-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="26614" checksum="E0E8423EB99586B0" modified="2008-01-15" version="1">MATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMPRLTGFEVCQRIREQSIVPIIVLTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVLRRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTPTEFALLAYLITHPNKVLTHRMLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU1</accession>
    <name>A9AXU1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2267"/>
    <dbReference type="EnsemblBacteria" id="ABX04907">
        <property type="protein sequence ID" value="ABX04907"/>
        <property type="gene ID" value="Haur_2267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2267"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OMA" id="PEAWEIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2295-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="39680" checksum="B41A2162881EBB81" modified="2008-01-15" version="1">MSNIHHDSAGLTIEHLSKMYNRSAKALDDLSLSIQAGELVSFLGPSGCGKTTTLNCIAGLEHPDTGTIRVGDFVLTDSAKKLFLQPEDRQLGMVFQSYALWPHMTVADNVGFGLRVAKIASSEIKQRVATILELVGLGHVAERYPFQLSGGQQQRVALARAVVTEPRLLLLDEPLSNLDAKVREQARTWLRDIQKRLGITTVYVTHDQAEALAMSDKIAVMSAGKLEQFDTPQAIYEQPATRFVAEFIGATTFLPATVVQHAPTLSQVSLSDGTCLEVRTALKLQQHQTIDLGIRSERVQVATSDHQTNVIAGAIRSSDYLGAKWHHQVETTIGALMVETLDYTSGNVRIYLPPEALMVLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXW8</accession>
    <name>A9AXW8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2294"/>
    <dbReference type="EnsemblBacteria" id="ABX04934">
        <property type="protein sequence ID" value="ABX04934"/>
        <property type="gene ID" value="Haur_2294"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2294"/>
    <dbReference type="eggNOG" id="COG0605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_0_1_0"/>
    <dbReference type="OMA" id="YLHSIFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2322-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="52"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="149"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27779" checksum="2131196E5E2234C7" modified="2008-01-15" version="1">MSERFNLSRRGFLGAVGLGSLAAIWGSKGASAKKYGGVGKTFDQATVPTNGKFTLPALPYDYGDLEPHLDAETMYIHHQKHHQALVTNLNAALADYPKLQSMNVAELLHGLSSLPSAIQTAVRNNAGGHANHAIWWATLSPKGGGNAGGALAAAINAKYGSFNSFKTTFNDIAARRFGSGWGWLSTDSKGTLYLASYPNQDSPYMEGLTPLLGVDVWEHAYYLKFRQKRAEFLSAWWNVINWGEVGRRYDLAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY38</accession>
    <name>A9AY38_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase-like amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4288"/>
    <dbReference type="EnsemblBacteria" id="ABX06920">
        <property type="protein sequence ID" value="ABX06920"/>
        <property type="gene ID" value="Haur_4288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4288"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="FCERNWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4340-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:pyridine nucleotide salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Isochorismatase-like"/>
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        <property type="entry name" value="NIC1"/>
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        <property type="entry name" value="PTHR47297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="25433" checksum="58DD5CB2488BBD60" modified="2008-01-15" version="1">MLANNSQAFLEYLDDWYANLPELPLDDLLIDGAERVAVTCVDIIVGFCTDGALASPRVQSIVAPIAELFKTAHAGGVRHFILPQDSHPVDAVEFGAFPVHCVRGTSEADTAPELRALPFADSFTIFEKNSLSAALSTGFPAWVAEHPEVDTYIITGDCSDLCVYQLAMFLRLDANARNVQRRVVLPAQCVDTYDTPLEVARELGLYAHPGDFHHVFSLHHMAANGVEVVKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY70</accession>
    <name>A9AY70_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4320"/>
    <dbReference type="EnsemblBacteria" id="ABX06952">
        <property type="protein sequence ID" value="ABX06952"/>
        <property type="gene ID" value="Haur_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4320"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_462147_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4372-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="590" mass="65162" checksum="7D44404CA6FF3F08" modified="2008-01-15" version="1">MQCAACGATTTNAHQRICAQCNAPLPQLLVAGALVMNQYRVVQPLREGGTGQIYLAEDTRTFDRKCILKRTILKGGNESRRLFATEAELLTRLRHPQIPQVFAYFEDAGVATIVMEYVAGRDLEHGLSQTLVDGTFMAGKPRPFEQVLRDAIVVCKILEYLHALKPALVHGDIKPANLIRDRDSNELFLVDFGAAATSGVGQTYGTPGYAAPEQYRNQRYPASDIYSLAATIYHLLTDDDPCEHPLRFPKLTSLSPRMQQVLGRALHDDLSQRPNATVFRDLLEETLEPTLVQPFKFPSGVTPHTGYDLAQAIQADWGYGLHALVNGDLNTWLRQHQQTELAIKVHRMLVQNERPERVLDFLVGSLAPNLLAAEVKFEYNTLLLPLDGMSATPLTVTARNRAAHIKAVDAPGWLQIGPKELYVVPEQPQQFQFGLDLARNPKPGQTASVSFEIRTSEEKPQRRKLKIQLAQGYLPKPDTGELWPLIAGLGGGAVLLSIVLAVIYHPNNTLLIEAAIGSLIGIIWTIILSERSTEVVLHILLSIGGAILAGIIYAIYILGAFNPFSLGAFFYALGGSLACNTIYHYFFKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC0</accession>
    <name>A9AYC0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0854"/>
    <dbReference type="EnsemblBacteria" id="ABX03502">
        <property type="protein sequence ID" value="ABX03502"/>
        <property type="gene ID" value="Haur_0854"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0854"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_655171_0_0_0"/>
    <dbReference type="OMA" id="NWLLIIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-868-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="44887" checksum="590F2B9775AC6E07" modified="2008-01-15" version="1">MALRECPNCRASVDDVNPFCSECGTRLNAAPTAAEGPTQALPRYDGQGGSFPPPEQNYGQAGSYPPPPQQNYGQGGSYPPQQNYGQAGSYPPPPQQNYGQGGSYPPPPQQNHGQAGSYPPPPQQNYGNQQPYTPANYQQPNYGAAYPNASVPTKRSNNTGIVIGIVVGILVLIGAGVAFLMDGDNDDPNNKVVAGNATSVATATARPTRTPAAEATEEPIPPTEEPSTGGLAFLEDDFSTTDEAWPDQETASKSGKYAYVEDAYQIHVYVNERIIWTSTNETYSDVDAQIDVKMVSGDPTNAAGLVLREQIDGAASGSLYVYQIDGQGNIAFRRYDKQTEEWTNLVDWKFSSVANDGIGATNRLRVVAVGSNFTFYLNGEKVATYNDDTYANGAVGFGASTFDNGDTLTEFDNLRMAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH3</accession>
    <name>A9AYH3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0907"/>
    <dbReference type="EnsemblBacteria" id="ABX03555">
        <property type="protein sequence ID" value="ABX03555"/>
        <property type="gene ID" value="Haur_0907"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0907"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1989553_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-921-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="13643" checksum="30D8325DD970A133" modified="2008-01-15" version="1">MHRLSIATISIASRRAMLHSLINPNPAYELIADITHAEALQLLPNLQPDIVVLDAAMLNINPLVALKSLTQWPNCPAIVVLTSGVGYEQRLWHDLGAQAIARLEQPETIEQALAQIARQAQVQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS0</accession>
    <name>A9AYS0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase 28 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2408"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05048">
        <property type="protein sequence ID" value="ABX05048"/>
        <property type="gene ID" value="Haur_2408"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2408"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_7_1_0"/>
    <dbReference type="OMA" id="NCIVVKN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2436-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006326">
        <property type="entry name" value="UDPGT_MGT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01426">
        <property type="entry name" value="MGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="447" mass="50110" checksum="B23A3B707456B954" modified="2008-01-15" version="1">MATIVISMFPEEGHLIPSFKLGKSLKAQGHQVYYLALADFEEYIRKQGFEYLPLFAEDFPKGFRAQQTERIANTRGRAFLKEVSQTAFYLKLFQTVHEDQNPIKRSLLEIGTDLCLFDGFLAPLSLMARHAGLEVISLSININLPQAANYPPVVTNIVPDNTPASLSKAGMAWKFSGLAIKITNLLIGYNFQKKLTELATHFGFSADLVVPAALFPRLRPQLEIPELVLCPQAFDFPRPSVEQGIFYCEPSIDLDRQEAAFDWSQIDPNKPLIFCTLGSQSHIYKPSRRFFQTVIDTMRSRPDWQLIMALGQKFQAHEFANVPANVQLLQWASVEQILPRTSVMITHGGVGTIKECVYFNVPMVVFPGNRDQPGYAARVVYHELGLMGSMGKVSAQALETMLNQVIQNPNFKQRVTAMGEEFRALEAASPALELIQSKLPHTRTVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT3</accession>
    <name>A9AYT3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2421"/>
    <dbReference type="EnsemblBacteria" id="ABX05061">
        <property type="protein sequence ID" value="ABX05061"/>
        <property type="gene ID" value="Haur_2421"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2421"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520512_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2449-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="304"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="402"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="57626" checksum="CE116AC34343019E" modified="2008-01-15" version="1">MRARVRRRVTWIITLSALLPLLSVWILVLYISYRAEEQSAERQQVALTDLAAEDFRRFLFNTTIELQDVAENIARETDPQTITAQQLSTLGLFRSSFAEVAIYSADGQRQVASSRFGDPTLPMSLTGAQLLADLSTRRVSFADPPSFTGTISRKLAPQEIPRFRVATQLLSSNNQALFLVADVSMQRIWTSTTRIETAAEMRVLILTEQGDLISAAKIESLLEHPEMRGIPLLGSEATVATYESVFGEEVLGVRTSIEPVDWILVVERPLEVIYGNVGRLAVSLLMIIFIATPIVIGVGWYVGRRIAGPIQTLYAGVTRFSENPNNFEPVLLDTRDELASLAGAFNTMASGLNASQKRLANLNEELEAQVVGRTSELHNALAEVQAQNLAQERLLDTVRRLSMPSIPITKHMVVMPLVGEFSADRANDISTTLLLTIEQERAKIVILDITGVPVVDNIVARAILDAAQAARLLGAQVILAGIRPDMAETLVNLHINLGMIESAATLEQAFKRGMEYLRVNRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYW5</accession>
    <name>A9AYW5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07005">
        <property type="protein sequence ID" value="ABX07005"/>
        <property type="gene ID" value="Haur_4373"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4373"/>
    <dbReference type="HOGENOM" id="CLU_989618_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4427-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="29924" checksum="903D1ED480082499" modified="2008-01-15" version="1">MPILLDLWLTLLPALAPNRWLASMGSVINRFSQAQGQQLWSQANELLQTIDLRSSAVGTYLVPSLFSGDGTPSIYAGAPWLFNGWLTLLLVLGLNIAGLGLSALVLFWLGQQLATTKPALSALPKQLWALTKMCLIIVGLGLLFGIPAFVAASFLLSASAFGAQLVLAAFGVLLIALWLYASLAPAAIIIGQQSALVALYQSYNLVRQQPREAFPLILASGVLIHGTAFLLRPLANDLISIIAASALFGLLSCSLQAAKLAFYSERVGSLAHRFPVALTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX3</accession>
    <name>A9AYX3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LamB/YcsF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4381"/>
    <dbReference type="EnsemblBacteria" id="ABX07013">
        <property type="protein sequence ID" value="ABX07013"/>
        <property type="gene ID" value="Haur_4381"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4381"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_0_0_0"/>
    <dbReference type="OMA" id="DRTYKQD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4435-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="26049" checksum="D065D396596D98E3" modified="2008-01-15" version="1">MIIDLNADLGEGSDFDAELMSLLSSCNIACGGHAGDQASMRTALQLAQQHNLCVGAHPSYPDRAHFGRVVLELEPSQLQASLTAQITQLQRLATEQGTKVHYVKPHGALYNQAAIDSDLAQLLITTIQTIDPSLALMGLAGSSLLEQAATAGLQTIAEGFIDRAYEIDGCLRSRSLAGAVHHEPNVALQQALALAKGMPFPSYTKLPIRLTVQSLCLHSDTPQALAFAQAVRTALVAEAITIQAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX5</accession>
    <name>A9AYX5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4383"/>
    <dbReference type="EnsemblBacteria" id="ABX07015">
        <property type="protein sequence ID" value="ABX07015"/>
        <property type="gene ID" value="Haur_4383"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4383"/>
    <dbReference type="HOGENOM" id="CLU_1254503_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4437-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025324">
        <property type="entry name" value="DUF4230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14014">
        <property type="entry name" value="DUF4230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="24124" checksum="81FDE251DDB9A24B" modified="2008-01-15" version="1">MRIRTMLMLVLVLALIGTVGYAFLSPSLGFDGLMAQPTSTIKPGMTVLQAIKRQAKLSTLAMSFTKDTTIIREHGLLGACTEEITYLGYFNVQAGIDLSKISEERLIVSNDGYPDQATVEIVLPDAELLSNELDTQNSRIIAQDTPKWLPGCSHEIADMTVEAQNTLREQVRQDALEKGILSQSQQQASEELGRLLTDVGYKNITIRASNGSVLYSTKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ53</accession>
    <name>A9AZ53_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0951"/>
    <dbReference type="EnsemblBacteria" id="ABX03599">
        <property type="protein sequence ID" value="ABX03599"/>
        <property type="gene ID" value="Haur_0951"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0951"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_2_0"/>
    <dbReference type="OMA" id="MIAYNGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-965-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29345" checksum="C0951B2B8D677987" modified="2008-01-15" version="1">MPIRMIATDIDLTLLDDRGQLPPTNIEALALAARQGIRVVLATARRREAAQEVAQRLHIPTALVCHNGARIWDERGREIAHHTIDLELAQRIAAMADKRSLPVVFTIDETNFVTAQASNLVGSRTVCTPVSSLELIVRLAPTRILCHGELATRAVEEILGRNSQLKQFRYLRSTGEVYSAVISHAEATKERALEHLCQAWSIQQSEVLAIGDADADVGMLRWAGVGVSLTGSMQQAIEAADWVAPSARFGGVAVAVHRYVLQHQNVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZA2</accession>
    <name>A9AZA2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetate--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1000"/>
    <dbReference type="EnsemblBacteria" id="ABX03648">
        <property type="protein sequence ID" value="ABX03648"/>
        <property type="gene ID" value="Haur_1000"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1000"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_0"/>
    <dbReference type="OMA" id="DHWWHDL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1016-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="7">
        <location>
            <begin position="49"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="5">
        <location>
            <begin position="105"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="6">
        <location>
            <begin position="552"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="653" mass="73152" checksum="9A2E1FA1E6EBD829" modified="2008-01-15" version="1">MTEHAAPTTVGQFSASNDAESAFYYPPAALVENSNVLAYAREKGFADVEAMRQWSIEHYQDFWADMATRMVDWYMPFSKVLDDSKAPFYQWFNDGKINIVHNALDRHVKTWRKNKLALIWESEKGDNKTYSYWQLFKRVNKFANVLKSMGVKKGDTVTIYLPRVPEIVIAMLACAKIGAMHSVVYGGFSVEALQTRIQDAQSRVVITADGGYMNGKVVELKKITDDAIKHSPVVEIVIVVKRTGHEVEMQQGRDLWYEELMALPIASTKCETEQLDAEHPLYMLYTSGTTGAPKGLVHTHGGYQVGVATTLHFNLDIKEDDVYWCAADPGWVTGHSYIVYGPLMLGATQVMYEGAPTFPFPNRWWNIVERYGVTVLYTAPTAIRGLMRFGEAWPNRHDLGSLRLLGSVGEPINPEAWRWYHRVIGRNNCPIMDTWWQTETGSMMITPNPTTPLKPGSGTRASFGIDADVVNDQGEHASDDEDGLLIIRNPWPSMLRTIYNNPERYIEQYWSRIPGVYTAGDSARKDEDGYFWVIGRIDDVIKVSGYRLGTAEVESALVSHPSVAEAAAIGLPHEVKGNAIHTFVILKNGYEANQDLEDALIAHVGKVMGPIARPEAVQFVPSLPKTRSGKIMRRVLKARALGLPEGDLSTLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ2</accession>
    <name>A9AZJ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2498"/>
    <dbReference type="EnsemblBacteria" id="ABX05136">
        <property type="protein sequence ID" value="ABX05136"/>
        <property type="gene ID" value="Haur_2498"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2498"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077604_0_0_0"/>
    <dbReference type="OMA" id="GWCLTHK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2526-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="245" mass="27771" checksum="F3F8E98AE66A9B4C" modified="2008-01-15" version="1">MQHADFCTIEYPDVSQLVSLFDLLPDVVFFCKDHAGRYQVVNETLRVRCGCRSKQELIGRLPEEVFPLELGASYASQDQQVIRSGVALNHRLEVHIYPDLRIGWCVTHKRPLRDRNGVVTGLVGISRDLRSPNRNAPTWRRVASSVEYLTEHFAEIATIQQLATIAQLSLSQYERAIQQIFELTPKQLLIKTRIDASIKLLAGNRSIAAIAATCGYADHSAFSRQFRLITGLTPRQYRHLLGRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B033</accession>
    <name>A9B033_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1092"/>
    <dbReference type="EnsemblBacteria" id="ABX03740">
        <property type="protein sequence ID" value="ABX03740"/>
        <property type="gene ID" value="Haur_1092"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1092"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078235_1_0_0"/>
    <dbReference type="OMA" id="IHACLFC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1112-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="58"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24847" checksum="70DD949A040AB3B2" modified="2008-01-15" version="1">MAWIPQRSQAVELLDTLTEHPELTANLAEMAWLYRLSGGYRLGWRLLQPFLQNHTSLLDLGAGNGQIGRWLQAASQQQSQLLQTFSLDLNRTIVASNQQALIGAGQALPFANQSIDIVFCAQMLHHCSSDQVIGLLREAQRVARRGIVIVDLQRSWLGYWGARLVGLGPLTSLGKHDGPLSVLRAWRSSEIQSMLQAAGIQRYHIKQTSLYWGLAIEPTAQAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B081</accession>
    <name>A9B081_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2552"/>
    <dbReference type="EnsemblBacteria" id="ABX05190">
        <property type="protein sequence ID" value="ABX05190"/>
        <property type="gene ID" value="Haur_2552"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2552"/>
    <dbReference type="HOGENOM" id="CLU_2537944_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2580-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735148" evidence="2">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="83" mass="9338" checksum="EDC61181B74B6F2D" modified="2008-01-15" version="1">MFRHFFKTIWMAAKYFLLGLATAALTAPQTGAESRQLLKKRILGLFDQTLPTTPSSNDHTEDGAASLDKQEYWQNGAEKYSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B0</accession>
    <name>A9B0B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2581"/>
    <dbReference type="EnsemblBacteria" id="ABX05219">
        <property type="protein sequence ID" value="ABX05219"/>
        <property type="gene ID" value="Haur_2581"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2581"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_226299_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2609-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="532"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="910"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="1245"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="1590"/>
            <end position="1785"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="1934"/>
            <end position="2128"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="2282"/>
            <end position="2470"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="2580"/>
            <end position="2756"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="550"/>
            <end position="557"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="926"/>
            <end position="933"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="1265"/>
            <end position="1272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="1606"/>
            <end position="1613"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1961"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="2298"/>
            <end position="2305"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="2598"/>
            <end position="2605"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2947" mass="328912" checksum="1D3004912AB89B8B" modified="2008-01-15" version="1">MKNSIQMIDRPPRIQPELPFNKFEIPSPPENPEDAISKLIQLALPMTMIVGYVFVTMFGGRGGGGALILIPMALSVLASTGFSIYSFIREKNQRLERERQYHEQIVELNKDMHGYHDLQRRFYRYNYPDTPSTIRVITDAKHDLEKPERTLRSNARIWERRVSDDDFGSVRLGMGTLPSTVVYEVRGGGNFSSPLAREAMKLDADSRYVSDIPIIITLRHKSEDEGDSKEKSTPITPTTHALGIAGARDAVYESIRSILAHYVVFHSPSDTRLYVLASKYNEWDWVETLPHCQPGEYEQLCFVSEIKQVADDADEEGDELDQYMEGIRKILSQRKMRMEDNEENSNNSGRGNPGLPFMLLVVDLLDMYEKAGERLRNIESDAALSILIEEGPQLGAAVIFLVPERSKVPGGCKSVIEIERTTPATNSKQAQHQQLFFRYAEQGVNTFRYIGAADNIVNREESRKLAEELSTLNLRQSAGANLADAVAFFDLMGYSSLDELKVDALKNWQRSIQPKYANWLRAKVGRMSGNKARTLVFSAKKDGVHGMVAGSTGSGKSELLISLIAVMAVTYDPSVVNFVLVDYKGGGAFKEFERLPHCVDIITNLAGDGVTRMFTAIKSEMQRRQVLNNETDTKNIVEYRKKNFHTTHYPYPYLFIIIDEFAEMIADRAEYRGELESITRIGRSLGVSLILAAQRPSGITDQMRSNIKFRISLRVETQGESREMLRRSDAAFLPTGIPGRGYLQVGNEEIELIQVAYTGDPYVDPNSVSQEKVIWPDRRRAEGVDPGIDTQDQSPPELYKVIVTTLDALSRDNNIPIQRAPWPNFLPRELALTQHLISDDPNVNAVTFEEYLLGIDDIMVGLPREHDLTLNPALNKWINGSSGWVEDLNWREYAMRPVVGLIDNPYAAKQIPLTVDFPRGHAVVFGGSGWGKTTFLRSMLMSLAATHSPNQMHMYILDLGGRNFSVLDKLPHSGAVIIPDGEGYEERVEQLLREINDIVDARKLLLNDAGIADIYQYNAVNPKNTQPAILVAIDNFAEFTETFGEGPDANVESVLDKLVSIARQAKPYAIHFIITIGSMAELSTQVFSLFTERYTLKLSDNTEYRAIVGGRVDDINDIPGRGYTKVGPQPLSFQVAVSAGISSDGSLDSTIEMKEIDQLAQFMSDYARTSGKHYAKPRRVDAMPKAILFKSMLPEMYATMLQREIRFEPDLRPQLNALMSEAWEDSIKPENADWLKVTVGVMSGNRPRTLQLEAKKDGVHGMIAGGTGAGKSELLMTLIIGLAVRYDPSILNFILVDYKGGGAFDPFKDMPHTVDLVTNLNKSRVRRMFTAINAEMGRRQALNARTGTKDIVEYRAKGFHLDPQWGPFPHLFIIIDEYAEMISDTPEFRDELESITRVGRSIGVNLLLASQRPIGVTDQMRANIKYRICLRVEDIDTSREMLRRSDAAFLPSGMPGRGYLQVGNENLDLIQVSYTGESYDYAVAADGTKAKFYELIVSMAQELLHPRPRPQTPWPAPLPDAITFEQLLNPRYVDKTYLPLMTLGRSQRISLNAFVGDWFENKGQWFGVDWNHVAMRAIVGVLDDPGNARQMPLILDFNKGHAVVFGASGWGKTTMIRSMVLSLAATHSPNEFNAHVLDLGGRNLEVLRAIPHVGTVILPDEQGYEERIQQLWRELNNVVDERKKLFSDAGVSTLAEYNSQNAAKPKPAILVAIDNFGEYIETFGDDKNNDANNLLEAFVALARQGKAYGLHILITASRLNILSSKLYSLFTERLTFRISDAGDYSSIVGTRLLEVEEIPGRGAAKVGRDALSYHIALPPGTIGKADVLGADGQPQVTEKLQIRGEAGQIRVIGKHMNAYIANNPGKYQPPLGIAALPKSSSYRQVLQEMHNIGRGDRPFVEELKEATAKTWDYNGGTGKQAGWLAACLGIVSGNRPRTLQLEAKRDGVHGMVAGGTGAGKSELLMTLIVGLALNYSPSILNFVLVDFKGGGAFKPFENMPHCVDIVTNLNKSAVDRMFTSIDAEIRRRQALNAMTGTKDIVEYRERGFHLKPEFGAYPHLFIIIDEYAEMFDSNPEYLPSLESITRVGRAQGVNLLLASQQPKGVTDQMRANIKLRLCLRVEQPDTSRELLRKPDAAFLPNGMPGRGYLQIGNENLELIQVSYTGESQIDDREVGVLWPEREPEPVSTSEDTPKLFDTVVQISRELVNYQPTPKPWPNFLPERVSLQSPIVNAKDNTIIVFQPAVTDWINGDTERLWPGVNWETEAMRTAALLVDDPNEATQLPFVFDFSTNHLAIYGDSGWGKTSLLRSIITSLAATHSPDELHAYVVDLGGRNYRSLRNLPHIGALIYADDETFEEQMLRLFSKMERLTRERQQIFSDAGVNTIYEYNQQFPDQALPAIVVAIDNIAIIHENYDAVEESILIPLVRRSLSVGIAFIVTANFPNNMSSRFGSLFGERITFKQGQQDRYMDIVGRGAIEFGDIPGRGYIRVGKRPLLFQSTLPVGLIGPDGRDHRNEAEELDLMGLMMQAKVQQLGGMKTTPDPIQILPQIVPLREMLDAANEVAEGKVIWSVVGQSNNLQPAMYDLKKIGPHAAIAGPPISGKTTLLYNWVLSLADRYTPEQVAMVLIDTRGRFFKYGGKRSFADLPHVLQTVSEIDQMPSLLENLQIECQAFAQQAISRPVYIFIDNFEDFSDEAESKRSVMNDIAVLTRRYGGEGVFVIIAGTLDGSVNDLRRRVMSANFGIGLRTAQAVESLRVMRTPSEVRGKELPMGRGFMVKAGQTTLIQVASPYTNGSQVVAEDASDEAERVINALDGWVETIAERHPERAAWSSGAITIGDKPVNIEQDPRVVQMSALIRQGIQRLMPRLKESNGEGSITESIMQNYITMDFVSWNSSERLRSMLHQMLIDQHMHDGLDLETATMMADMTNSDDESLILAFESTLVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C8</accession>
    <name>A9B0C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2599"/>
    <dbReference type="EnsemblBacteria" id="ABX05237">
        <property type="protein sequence ID" value="ABX05237"/>
        <property type="gene ID" value="Haur_2599"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2599"/>
    <dbReference type="eggNOG" id="COG5295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010499_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2627-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1061" mass="115501" checksum="65F58610D8B362A6" modified="2008-01-15" version="1">MNKPSKIIVLITLMALLVGALQRPVAPVIASEPQIPTSPGTWSQAFADPLKLDPGYMPLRPIEWNGTLYAGIVGVDGFEPGVGYWSGQQWLKLDGLSGEVDSVVVHQNRLFAAGRLTLGGNHISIAFWDGNLWTAMPTQFSPNIFILASHNDQLYVGGYSEQIADQASGLLLRWDDTQWHPVAEGIFGAVMSILSRPDGLYLGGVFQLNGQNTGLIHWNGAQWQSVGGGVQGMVMDVEWANDQLYISGKFTSTLEPTMQNIAAWNGTSWNTFGTGIVSPTHNLALLDGDLYALSQTDRPYPYQTIYQLQRWDATHWTTLSNLSETSSVLNWSRYPDVVLVNYQQELLAFGPIGFVDRNVQTLRWGDSALRWKGNSWEAMTPNGISAMKLALAVDGEDVYAASGRMTWGNGQASLAHLSPNNQWQLLIAYDSQQPQYAQALQKYQQNFFSIYNSTLYQAVNNAWNQASPATVESLAQANDLLYVAGDFEQFNGVTARNLVTWNGTQWQALNTPASFDRVVIVEAHGDDVYISDGFQLAHWNGSQWTTLATNVVNIGSIEPTANGVYIAGTFSSVGGIATPKIAYWNGTAWSGLTGEIDGSIYDLEMGADGLYVAGWFRGIINGIYSPGILRWDGTTWHGLGGGVKSSATPNQPGAVTLLAATPTRMLLYGSFDRVGNTYESKQIAAWEYGNEPLIKAKSDYGLTYRPQSVTVNVLANDWSDQPNQLQLVSVSSPSHGTAVINGNSVVYRPEAQFEGVETLTYVVRDPINAVTSTAQLQVHVWNHFPSIADQEQAVYPFTETLLDPLDGLIDLNGDSLTITQASAVSGTVTIVNNQLRYMPPNQHHFTDVVTYRVSDGHGGQQSARINIHSIDTIVTATADYATTYRPYSVRVDVIANDWTINGEPLAVVAVDAAIHGTATISGNQVHYIPAETFQGTETLTYTVRNQTRGITATATLTIEVQNHVPTVAPITITVQPNSITTLNVMANAVDLNGDQLTITQASTTAGTVAVVNNRLRYTAPNSYPFVATISYTINDGHGGSQVGTIVVNSVKYHLFLPYTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N3</accession>
    <name>A9B0N3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ordered locus">Haur_4620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with KhpB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4620"/>
    <dbReference type="EnsemblBacteria" id="ABX07251">
        <property type="protein sequence ID" value="ABX07251"/>
        <property type="gene ID" value="Haur_4620"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4620"/>
    <dbReference type="eggNOG" id="COG1837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132074_1_1_0"/>
    <dbReference type="OMA" id="CGPRITL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4677-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="87" mass="9764" checksum="20740026CC3ABFC1" modified="2008-01-15" version="1">MPRTRRLPKDAAMEDLLKYIVEGLIDTDEIKISKRTGHHSITLDLRIPQSEAGKVIGRNGRVVKAIRDVLGIVGARQNKRVHLEVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S2</accession>
    <name>A9B0S2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1144"/>
    <dbReference type="EnsemblBacteria" id="ABX03792">
        <property type="protein sequence ID" value="ABX03792"/>
        <property type="gene ID" value="Haur_1144"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1144"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055284_2_0_0"/>
    <dbReference type="OMA" id="SCAIPGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1165-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="12"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="48"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="411" mass="45683" checksum="BB5047B5CCA19924" modified="2008-01-15" version="1">MKKSTPSKRALVLAGGGISGAVYEIGALRAIDDLLTTLSINDFDMYVGTSAGSLISSCLANGITTRELLRILEGALPDAKRLQRDQILALNLRGLIKRGRRLPRLLAQRAIETLRRPQDFAPLDWAWKLLEGLPNGIYSTNSLERYLRHFLTERGSNHFAELQRELYIVATELDSGDRAVFGEGNLRNVPISAAVAASSAMPIVYEPVRINGVDYIDGGVRGTASLDVAIDRGAKLIVCVNPLVAFDNRKHQLGSRIADAGIQAIGNQVFRTFIQAGLHYHIKKLRQQHPDVDIILIEPRADDAIVFAEHVLHYDERMLLARHGYESATIRLADKYQDYKAILAKHGVQISRQRVAKELHHLFASDDADTLHSLLENDPNGKRLTHPQKSWRTVNLAHTLDDLDARLGNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B152</accession>
    <name>A9B152_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2692"/>
    <dbReference type="EnsemblBacteria" id="ABX05330">
        <property type="protein sequence ID" value="ABX05330"/>
        <property type="gene ID" value="Haur_2692"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2692"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101313_0_0_0"/>
    <dbReference type="OMA" id="GCSVYAK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2723-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027981">
        <property type="entry name" value="DUF4446"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14584">
        <property type="entry name" value="DUF4446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="176" mass="19290" checksum="47342B41EA1CC54C" modified="2008-01-15" version="1">MIAFWTTYGFYLWIGSGLLIIGLLIWIGRLSKRLSAIDQRYTTLTKGVDAEHLEDIWLQRSLQVAHHDDQITALEREVRRLGRSSLHHVGLVRFNPFGDVGGDQSYALALLDGEQSGVVLSSIYSRSGVRTYAKAVQRGQSTHTLSEEEVASIAQALGQFTSVESAAQPATTGGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B153</accession>
    <name>A9B153_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal small subunit Rsm22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2693</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2693"/>
    <dbReference type="EnsemblBacteria" id="ABX05331">
        <property type="protein sequence ID" value="ABX05331"/>
        <property type="gene ID" value="Haur_2693"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2693"/>
    <dbReference type="eggNOG" id="COG5459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072591_0_0_0"/>
    <dbReference type="OMA" id="DWCHFVQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2724-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="36162" checksum="8FF327790E746089" modified="2008-01-15" version="1">MLPPALRVALERELTGTDQRRLAAAASGLSERYRAGHSRTTAPFVQNAADVLAYAATRMPATLGAIKAACAEIAQRQPNFQPQTQLDLGAGTGAATWAASQTWSSLLQHQLIERENTMLQLGQRLMQAGPTSLQQARWQQANLPNANALGNYDLVTIGYVLGELNATQRQQLLLQAWQASSGVLLIVEPGTPRGFELILAARTFLLEQQAHLIAPCPHQQTCPMQANDWCHFATRIERTRFHRSLKAAELGYEDEKSSYIAVSRQSSQLAQARVIRHPSQQPQRIQLQLCTPQGLRSITINKRDAQWKQARKAEWGDSFELNPTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J8</accession>
    <name>A9B1J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1235</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1235"/>
    <dbReference type="EnsemblBacteria" id="ABX03883">
        <property type="protein sequence ID" value="ABX03883"/>
        <property type="gene ID" value="Haur_1235"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1235"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_4_0"/>
    <dbReference type="OMA" id="TMMSVLS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1257-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="66"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="31556" checksum="E519F472F4498707" modified="2008-01-15" version="1">MAKWRSWLGLAPASIIMLGLFGSSLGYGIAQSLGWLPFLDQRELSLAAYRNVLVGQQLGGQWWSALLFSLWVSCAATFGSACICLGLLSSIAERQQHYRGLSIVSNLHLAIPHSVWAMALLLMLSQSGILARIGFAVGWLDQPKDFPVLVRDRWGIGIILAYITKEVPFLLLIGLATLRQQGRAYLLVAQSLGANRWQRLRLVLWPLLAPSLISGSFLVFSFIFGAYEVPALVGVRYPEMLATMALELFLNPDLQARAEGMAVSMLMSLIILAVVGLAWRWREQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1V0</accession>
    <name>A9B1V0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BamHI-like type II restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2754"/>
    <dbReference type="EnsemblBacteria" id="ABX05392">
        <property type="protein sequence ID" value="ABX05392"/>
        <property type="gene ID" value="Haur_2754"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2754"/>
    <dbReference type="HOGENOM" id="CLU_2342909_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2785-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011338">
        <property type="entry name" value="BamHI/BglII/BstY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004194">
        <property type="entry name" value="Restrct_endonuc_II_BamHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02923">
        <property type="entry name" value="BamHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="97" mass="10693" checksum="51770DEFA7A69759" modified="2008-01-15" version="1">MKIIHEERLIDAGNFSLTTDWNTIYADIIEAIATIRWPTNGAVFSLNPIDKGNGVKPIKTACMDHLAKKGWLLEHSIDIATAKKPGPMDASYKTPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W1</accession>
    <name>A9B1W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2765"/>
    <dbReference type="EnsemblBacteria" id="ABX05403">
        <property type="protein sequence ID" value="ABX05403"/>
        <property type="gene ID" value="Haur_2765"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2765"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2633249_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2796-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8928" checksum="ED6595D5A926D727" modified="2008-01-15" version="1">MPRHGDQPTTRELEIAELSINGYSCDEIALQLSLSPATIRTYLRNIYAKMDVSNIRALTVKLYKLERRSEFTWKVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X6</accession>
    <name>A9B1X6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2780"/>
    <dbReference type="EnsemblBacteria" id="ABX05418">
        <property type="protein sequence ID" value="ABX05418"/>
        <property type="gene ID" value="Haur_2780"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2780"/>
    <dbReference type="eggNOG" id="COG0809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039110_2_0_0"/>
    <dbReference type="OMA" id="SLWHVQT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2811-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="38441" checksum="11BFA68FE58429B0" modified="2008-01-15" version="1">MLATIDFELPAVLEAGEPPEARGLERDQVRLMVSHSRSNTIEHYRFDQLSMILQAGDVLAINTSGTLNAAIPATDASGQRFMVHLSTQLLAELWLVEVRLPHGTSSQPYRAALAGNSLNLPSGGQIDIHRGYANDGSAINRLWIASLRLPQPLPHYLAEHAKPIHYQYVAADWPNSYYQTVYATELGSAEMPSAGRAFSERLLTRLVAQGIQIAPLLLHTGVASLEDHEPPYAEWYRVPATSADLINRARADHRRVIAVGTTSVRAIESTVDQRGLVHPQAGWTELVITPEHGLQAVDGILTGLHEPKATHLAMLAALAGYQHLELCYQAALEQHYLWHEFGDLHLILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z1</accession>
    <name>A9B1Z1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ordered locus">Haur_2795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2795"/>
    <dbReference type="EnsemblBacteria" id="ABX05433">
        <property type="protein sequence ID" value="ABX05433"/>
        <property type="gene ID" value="Haur_2795"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2795"/>
    <dbReference type="eggNOG" id="COG0809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039110_1_0_0"/>
    <dbReference type="OMA" id="YSYGDGM"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38237" checksum="2821EC2B16886873" modified="2008-01-15" version="1">MLPIADFDYHLPPERIAQTPIEPRDHSRLLVLDRATGQLEHRHFYEIGRYLRPGDLLVANDSRVLPARLYGQKASGGKTELLLLKQRDAQRWEALIKGKVAVGTRLIITGHRGAQVQATVEELLESGSRIICFEQPINDRLPELGSMPTPPYITAPLTDPERYQTVYSAQAGSAAAPTAGLHWTPALIEQVKALGVGWASVTLHVGLDTFRPVQTENALDHQIHSEWYELSAETAQAINATRAAGGRIITVGTTSTRVLETVSQSQDVSLTAGEIQAAAGWSSIYIYPPYEYRVVNSLITNFHLPKSTLLLLVSALASRDLIMQAYAEAVERQYRFFSFGDAMLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B229</accession>
    <name>A9B229_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3291 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4748"/>
    <dbReference type="EnsemblBacteria" id="ABX07379">
        <property type="protein sequence ID" value="ABX07379"/>
        <property type="gene ID" value="Haur_4748"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4748"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119287_0_0_0"/>
    <dbReference type="OMA" id="VNMSVWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4806-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021708">
        <property type="entry name" value="DUF3291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11695">
        <property type="entry name" value="DUF3291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3291" evidence="1">
        <location>
            <begin position="6"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="156" mass="17957" checksum="9EBFCA54610CF192" modified="2008-01-15" version="1">MADYQLAQLNIGTIKAPLDTPLMADFTNNLDRINALAEASEGFVWRLKDDSGNATDYRPLDPLTIVNMSVWQDLDSLMQYVYKSEHVAMMRRRKEWFERMETAFMVLWWVPAGHEPSVAEALERLEHLRNNGESSYAFSFRKPFAAPNSIQVVEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G0</accession>
    <name>A9B2G0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1360"/>
    <dbReference type="REBASE" id="16526">
        <property type="entry name" value="M.HauORF1360P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04005">
        <property type="protein sequence ID" value="ABX04005"/>
        <property type="gene ID" value="Haur_1360"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1360"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2617163_0_0_0"/>
    <dbReference type="OMA" id="AIETHSK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1381-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="78" mass="8511" checksum="B32489B8B4ED8A9B" modified="2008-01-15" version="1">MSDMTVTDLFCSAGGSSTGVVNAGATVRMALNHWKLVIETNNMNHPDTDHDCTDIQACDPRRYPRTTILIASPECVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W9</accession>
    <name>A9B2W9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transposase, IS605 OrfB family</fullName>
            <ecNumber evidence="14">2.1.1.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_3396</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06032">
        <property type="protein sequence ID" value="ABX06032"/>
        <property type="gene ID" value="Haur_3396"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3396"/>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_0_1_0"/>
    <dbReference type="OMA" id="WYEMHRQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3433-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="174"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="291"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX06032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="43947" checksum="3D565EFBD1C2CDAA" modified="2008-01-15" version="1">MRMLTRCYKYRLQLTPTHVETLVQWAGCRRFVWNWALHCKQTHYQTTGQRLSYQRLAAALVDLKRQPKTAFLRDCHSQPLQQTLMDLETAFSNFFAKRAKYPRFKSRKITPHSLRFPQGVIVVDEHTISVPKIGLIRAIIHRPLQGIAKSATIKQDATGAWWVIFVCHIDLPDVQPTADRPVGIDVGLESFTTLSTGEKTAPPKFYCRSQKKLARAQRKLSRAQKGSNNRLKAKKHVARIHKKINNQRADWLHKHALGIVRQFDVVCIEDLNIKGLARTKLAKSFSDAALSTFMQRLQEKAEWHGRRVVKIGRFYASSKTCHFCHSKTALTLADRVWTCPTCGTTHDRDGNAAINMLYEGLRLLAVGTTESQNAARDGVNPAKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X7</accession>
    <name>A9B2X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3404"/>
    <dbReference type="EnsemblBacteria" id="ABX06040">
        <property type="protein sequence ID" value="ABX06040"/>
        <property type="gene ID" value="Haur_3404"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3404"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061564_0_0_0"/>
    <dbReference type="OMA" id="HAILITM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3441-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="246"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="39154" checksum="AE0D875BE437AC9E" modified="2008-01-15" version="1">MKALLAWLAQVDHPLEDVRRRGQIIISVMCALLVIVVIAIPSLLFNPKPLTSAVALGLGLVLAVVVIPLARRGKVTFAGWIVVITTSVIVSIPMMLRGETSYTLAYLLVPVLIAGVVLRPWQILMVLVGAWVIIGTLAFVYPTTDQVATTGGVVTHAILITMIGSIISFVNSRITVGAFHAVSEGQRTIEQNAKQLVELNSSLEAQVHERTADLENALMKLQDRASTQERLLDEIEQQREVIREMSVPVLPVAAKVLVMPLIGALDSERLTRLQENALQAVQRQSIKHLVLDITGVVVVDSQVAQGFISVVRSVRLLGAETMLVGIRPEVAQAMVSLGLELDSISTSATLQEGLQRIPNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B303</accession>
    <name>A9B303_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4836"/>
    <dbReference type="EnsemblBacteria" id="ABX07466">
        <property type="protein sequence ID" value="ABX07466"/>
        <property type="gene ID" value="Haur_4836"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4836"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_0"/>
    <dbReference type="OMA" id="MEVYRYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4895-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="21019" checksum="B4B8B437CD505249" modified="2008-01-15" version="1">MMTDDLKSPKKPSAQRSDAQQNHGRIMAAAKARFASDGPSAAMDAIARDAGVAVGTLYHHFGSKEGLLNLVIQEHFQVVTDFLASLQDSADPWWAVEQVVRGMAKRQIKDRAFKTMIHQHSNLIETTSQAKRGIDPAIQALIDRAQAAGLVRPDLRAGDLSALLAGLPIGDDQAEQRERYLLIVLQGIKSENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C0</accession>
    <name>A9B3C0_HERA2</name>
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        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_1439</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1439"/>
    <dbReference type="EnsemblBacteria" id="ABX04083">
        <property type="protein sequence ID" value="ABX04083"/>
        <property type="gene ID" value="Haur_1439"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1439"/>
    <dbReference type="eggNOG" id="COG3393">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-1461-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="113"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="244" mass="27204" checksum="80CA3FF1F9DD2C4A" modified="2008-01-15" version="1">MELALEQVVDGFVRGWVYSRALATTQLKCLGQHYHVSFGAVINGRSDEFLIFDQGQPANVADFGRTISQQYPQLAHWLTIFSQTPSDYASVLAPLGYQPLYRETLMSCGLSDVRFEPQSNVQRLSATTILPNNAEFAKQPFALERIDDAQLGQYLIDIEGQLAAVARLVSWPEGIALVDSVVTAPSFRRRGLARQLMQQLLNDAVAKNCQHSVLVASALGAPLYRQLGYRDRAEVLIFRREQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3D1</accession>
    <name>A9B3D1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1450"/>
    <dbReference type="EnsemblBacteria" id="ABX04094">
        <property type="protein sequence ID" value="ABX04094"/>
        <property type="gene ID" value="Haur_1450"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1450"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_240134_0_0_0"/>
    <dbReference type="OMA" id="QATHCLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1472-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
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    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
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    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="1643"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1774" mass="199908" checksum="68002DC81A2AA735" modified="2008-01-15" version="1">MTQSTWPATSELPAIPKVRILGEIGRGLHSTVYRCVRDGQTYALKIPRLNGNQSPTMAAAAFRREASALALVRHPSLPEVIEVDHYNEMPYIIMELVQGQTLLDLVALGPLPESLVIRLIKDLASALAAVHRQGITHRDIQPRNMLMQPSGNIKLIDFGFASHNSLDPEQTHVLGTLRYSSPEQTGYLKRNVDARSDLYAFGAVLFECLVGVPPFNASNITDLIRQHAVVLAPDVRSMAPHVSPALAEIVARLLAKDPDDRYQTAEGLLSDINQIDSLNLMLAAGRPIRLGADDLWTGALYDNDLIGRDAELAILRQGWNSARQGHGSVIAIKGAMGLGKSQLGREMLHRARSLGGLTFGSTCVKDSALPYSALRSPFEQYVHYLELMPESQRRHAEEQLRQFVQGYQELMLRTFPCLQPIFSHTKQPELVTDYERFNTILADLLLWMTRVHPAAVWFIDDLQAIDDASFSVIRRIIGRIQQVPLFLIISLNDSVDSQQIYERLTLNQPIPIQEILLHPLTDQAATQFITSYLGGYNVDQQIINEIVARSVGSPFALREYIQTLLDTGMLRLVNTCWMIDDQSLTKLALPSHVVRLVLSRIDELSPKVRAILELAAVLGFQFRRNSLLALWQGEPSEVYEALTIGGRSHLIERSASGHYHFAHQNIYQVFLEGITPEQQQQLHAQIAKNLDHEQLEPEAMYQLAYHYARAKSSDPTFLARGFTILSNAGQVALENYAYDEAYHFFEQAYQIAQGQSLPFQAQQHAQFAQLCLRLGQNQTALAHLQAALEQTSEPDHQARLLTAIAHIHAWQQQPRDIWRYFDQAFEALNEPALDRSLIGLLSDIGRSLGRLLKSSVPWLQPSSPQQQQRIIILLEIYDTVGMYAYLNSQMLLLVSLFLRSLVWARRGRTRPARVRALSNYASMWAMVGQRHLAKRALNKAKTIATTPTADRMLQARVALYEGFISHIIGDEVQAERLLRTTLRQYATTIDSLAYGHATADSVLLLFLRGHVLEAWQLVQETFERFEQHNHRNEQTWFLELWAAPLLITLGSTAEAQRYPVPDIKERQQWLLAWKNLADASQMIVNLEQGDPGQQNDQLLRHFNQQHRNNPRFMPFHSRYMYILQGYIRIAQFLQQRKRVTARRLRIAARQALLVATTPILRGHALVIFAAAHGFDGRFAQALELLGQAEQLAHLHDAPWILYEAHRIRAHLFGMQQQMAAAKREASRAYTIAFDHQWVLRMRNIAVAFQLDDPERLNSTTSIISDDALRPDDSRMQRLLDALLSVSLAWAQSYDLDEQAQTALDSVIRILGAERAFLFLLENDDLQLRAARDASNNPVSETLQGYSRTVLERVRITQKPVIVTGADDALITSSESVTAHNLRSVLAAPLMLDGRFLGVVYLDNRLAWGFFSKEDEVILRAITTHIALGLEKSRTTQLEIHINAEREQRRLAERLRVLSTVLNATLDLADVLRYVLIQLNSLLPYYGACIALREENELKFEQVESPSPTLWVRGTKISINDDPLFKQLATLRQPLIINDITQDPRFKGYGEHPARSWLGLPLLVRGEIVGFLAIDRDEPHAISEHEAELGMVFASQAAIAIANAQLFGQVQRLAITDSLTQVSNRRHFFELAERQWILTCSSDHPLSAMMLDVDHFKRVNDSYGHSVGDLVLRTVADLCRANLRPSDLLGRYGGEEFAILLPDTDVSAALTIAERLRVAIANHVINHEQASINLTVSIGVTGLSKDDNSVASLLDRADRGLYIAKETGRDRVTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F9</accession>
    <name>A9B3F9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1478"/>
    <dbReference type="EnsemblBacteria" id="ABX04122">
        <property type="protein sequence ID" value="ABX04122"/>
        <property type="gene ID" value="Haur_1478"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1478"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_3_3_0"/>
    <dbReference type="OMA" id="NAVLYFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1500-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="290" mass="32906" checksum="13B23C6A7170046B" modified="2008-01-15" version="1">MGEFGGIALIFIAVILFFFLISAIKIIPEYEKGVIFRLGRLVGVRGPGLFFVIPMLERMFRIDTRVITMDVPAQEVITRDNVTIRVNAVLYFLVIDPGKAVVNVMDYIRATMQIAQTTLRSVVGQFELDEMLSQREQINHRLQQIIDEQTEPWGIKVNIVEIKDVELPQSMQRAMAKQAEAEREKRAKIIHADGEFQASKRLAEAADVISREPVTLQLRYLQTLTEIAVEKNSTLVFPLPIDLIRPFIDRAYSGVQNDHYSEGGKKPNEPRTAAEPRRGLFDPMTGLPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3H2</accession>
    <name>A9B3H2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1491"/>
    <dbReference type="EnsemblBacteria" id="ABX04135">
        <property type="protein sequence ID" value="ABX04135"/>
        <property type="gene ID" value="Haur_1491"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1491"/>
    <dbReference type="eggNOG" id="ENOG50308PC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080080_1_0_0"/>
    <dbReference type="OMA" id="QHEVAYY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1513-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032531">
        <property type="entry name" value="DUF4956"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16316">
        <property type="entry name" value="DUF4956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="24029" checksum="D32A89EB0F8676F6" modified="2008-01-15" version="1">MTTDLTQFLLGAGFNLLVTLLIVRGVYYPVTQDKNFVFTFIGFNMIIYFVLGFLTSVEVGVGVGFGLFAIFSLLRYRTDEIPIREMTYLFILIALGVMNSLMHSGSLLQIGIANAVILVILFVLEKGWGFQFEANKRVAYDKIELIGPARSEELLADLRERTGIAVKRVEIGRIDLLHDMADLKIFYDEMPRLSAKRQSTTTRVLRDQHQLP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P8</accession>
    <name>TRMD_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmD</name>
        <name type="ordered locus">Haur_2982</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B3P8"/>
    <dbReference type="SMR" id="A9B3P8"/>
    <dbReference type="STRING" id="316274.Haur_2982"/>
    <dbReference type="EnsemblBacteria" id="ABX05620">
        <property type="protein sequence ID" value="ABX05620"/>
        <property type="gene ID" value="Haur_2982"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2982"/>
    <dbReference type="eggNOG" id="COG0336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047363_0_1_0"/>
    <dbReference type="OMA" id="ILCGHYK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000130179" description="tRNA (guanine-N(1)-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <sequence length="254" mass="28557" checksum="3EAE2E1332599768" modified="2008-01-15" version="1">MRFDILTLFPAMFTGPLTESILKRAAQAELLQFHLHDIRDYATDKHKMVDDSPTGGGAGMVMKPGPLALCTQTVLSADPNPAPVVLMTPSGRVFNQTIAREWAQLPRLVLVCGHYEGIDERYIERYVTDQVSLGDFVLTGGELAAMTIVDAVGRLVPEVLDPESLLHESHDDGLLEYPHYTKPAEWNGVAVPPILLSGHHAKIAQWRHEQRLRRTLERRPDMLRHATLSKKDRQLLKEWGWEEKSEGKNQKAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R9</accession>
    <name>A9B3R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3419"/>
    <dbReference type="EnsemblBacteria" id="ABX06055">
        <property type="protein sequence ID" value="ABX06055"/>
        <property type="gene ID" value="Haur_3419"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3419"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140387_0_0_0"/>
    <dbReference type="OMA" id="RGGCWFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3456-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="13689" checksum="BDBB88F912CC7226" modified="2008-01-15" version="1">MQLVALDHIQLAMPAGQEAQARWFYSTLLGLDEVAKPIQLQARGGCWFRSATIELHLGVEADFRPARKAHPAFRVTDLGQARAELNSAGIAIVEDDSLPHVRRFFVADPFGNRIEFVQVGDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-02-10" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3S1</accession>
    <name>A9B3S1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minC</name>
        <name evidence="7" type="ordered locus">Haur_3421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MinC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3421"/>
    <dbReference type="EnsemblBacteria" id="ABX06057">
        <property type="protein sequence ID" value="ABX06057"/>
        <property type="gene ID" value="Haur_3421"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3421"/>
    <dbReference type="eggNOG" id="COG0850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048711_0_0_0"/>
    <dbReference type="OMA" id="EMECAYI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_N" evidence="6">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="MinC_C" evidence="5">
        <location>
            <begin position="120"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24288" checksum="32D0652B655FAE69" modified="2008-01-15" version="1">MRDMEERITLKGSRDGLRLILHPTAAWAEVLEALRKQLAQGPSFYHGAKLLIDVGERSITDVELQAILAIMAEHDIEPAALITIAPTNRTTGRQAGVETRHPDSLRSTPPPVVQGEGLFLWRTVRSGQAIRHQGHIVVVGDVNAGAEISAHGSVIIWGRLRGSVHAGVGGNQQAIVCALELRPTLLRIADNLARTPDNHRPTGPEQASLDGDNIVVVPWDAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z2</accession>
    <name>A9B3Z2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3492</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3492"/>
    <dbReference type="EnsemblBacteria" id="ABX06128">
        <property type="protein sequence ID" value="ABX06128"/>
        <property type="gene ID" value="Haur_3492"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3492"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_434060_0_0_0"/>
    <dbReference type="OMA" id="ICDPPVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3529-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="6">
        <location>
            <begin position="12"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="7">
        <location>
            <begin position="254"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="560" mass="62274" checksum="1569DCA217B8B5F7" modified="2008-01-15" version="1">MHIEILYRDEQILVINKPTGVATHAPQGDLALTDVERALRAQLQLEYLAIHQRLDRDTSGVMLFALDPAANANLATAFAEHTIEKTYQALVYGVPIQTQGVIDAALAPAGDGMIQVASAHDRRAQSAITHYRVLVSSPDQRFSLLELQPKTGRTHQLRVHCECLGHPIVGDPLYDVARAAPRLMLHASELRFTHPLTQQPLHIQAPTPALFTRVAQGLPELQQSTELAALNGLIELAAERRAVLAADPATTIFRVFHGPSDGLTHPWLQHWTVDKLDQVLIASCYDEHVRQVPASLINALVAQWQPQAIYAKYRPRAAAKVDEAAMAELAPTRPVWGEPIEQVVVQEAGLSYELRPNDGLSIGLYADMRETRQRVRNLLAKRQLRVLNTFAYTCGFGVAAVADAPEAIVTNLDLSRRSLDWGKINYGLNQLAVEDRQFVFGDVFDWLSRWVRQGRQFDVVILDPPSFARNRGKRWRAEEDYADLVALAVQLLPADGHLIACCNHVGLSRRQFRGQVERGMQQGRWHGTIEANYPASPLDYPAAYGESHLKIILATGQTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B445</accession>
    <name>A9B445_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4948"/>
    <dbReference type="EnsemblBacteria" id="ABX07578">
        <property type="protein sequence ID" value="ABX07578"/>
        <property type="gene ID" value="Haur_4948"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4948"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_2_2_0"/>
    <dbReference type="OMA" id="DTRHFDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5011-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="263"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="374" mass="38421" checksum="74845ECB9496DA74" modified="2008-01-15" version="1">MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQAGVDAYSNVIRAVYNRGNPSVVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVLVNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEFGDSAAVQVGDVVVAIGNPYGENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFILDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKGIIITQLYNGPAAEAGLQVGDVIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGRTRDVQVLVGARPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A6</accession>
    <name>A9B4A6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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            <authorList>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </evidence>
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    <sequence length="124" mass="14216" checksum="7660A1CCE649756E" modified="2008-01-15" version="1">MIGGGLIFSLTASPSRCERPAQRSNPMMQEYDLSYQRQHELLEHLAELANWWRFANTARRPMLVEAYHETLDALYTAGWNAELAPPQLLPPWLMPDCYLAKHPHPCANDPQSLHDLFGERDCIA</sequence>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0017"/>
    <dbReference type="eggNOG" id="COG2311">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_036065_2_0_0"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-17-MON"/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <end position="45"/>
        </location>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
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    </evidence>
    <sequence length="374" mass="41179" checksum="355BDB63EAF13BC7" modified="2008-01-15" version="1">MAIVSRSKTTNVVKDSQRIVGYDVARALAILAMVIVHFALTFVNIEQPTTNGLLSLIVQFCEGRAAALFVVLAGVGLSLIARTQANPSSEAIQAKRWTLTKRGLFLLGLGLLNLTIWPGDILRVYGVSFLLIAWLFQSSNRRILGLALGFMLAFVGLMLRFNFNQNWDWTTLEYTNLWTIKGGLRNLFFDGFRSVFPWTSLIFFGIWLGRQNVQAAHVRWRLFWIGLSVALGVQIGSIGLTYVFSNVWPILGQADAELLFSTGSIPPMPLFLLSAGGVALAIIMSCVQLSQLFGASRIIHGLAATGQLALTWYIGHVVIGLGVLTSLGFYQNQSLATSLWLALGFFGLAVGCSVWWKKRFNNGPLETVLRWATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E3</accession>
    <name>A9B4E3_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
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                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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            <end position="272"/>
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            <dbReference type="Pfam" id="PF12706"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX02700.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="36069" checksum="27CDB16C40C22D53" modified="2008-01-15" version="1">MTTMTVRFWGVRGSHPVSGPEYLKYGGNTLCVEVEANGHTIILDAGTGIINLGKSLNARAKASGKPIDVTILFSHMHHDHTQGFPFFTPAYRGDTNMHIFGPGIFERDLEETLAKTMLPPVFPVSMAELPAQKIVSSIRETDVLLLSEAVGGAMLRNRFHDNLSDIDENMIVIKALRSYAHPDGVLVYRIEWQGMSVVYATDTEGYINGDQRLAQFAQGADVLIHDAQYTEEHYLGKAPGFGSTQGWGHSTATMACDVAKSAKVGTLVLFHHEPTYGDDVIETIENHAKSMFAGAVAAREGLELVLNQPQPEVASVADASTAVTEPLSSDVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
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                <person name="Tice H."/>
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                <person name="Richardson P."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <property type="gene ID" value="Haur_0056"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0056"/>
    <dbReference type="eggNOG" id="COG1075">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049416_0_0_0"/>
    <dbReference type="OMA" id="CMNDLQW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-56-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="387" mass="42583" checksum="4A9BB8FEDCA9DA6D" modified="2008-01-15" version="1">MPKAHLYGRDLQGISRLAIEATTQVTNISEGLFATIMRRPNRRIGGIPGLVYRQIHGITRLVGWSLDQLFGALAPANSQRVSSRQRNDLIAALNGVMGDYLVASNNPLQTSMSLRVAGAELEPAAIAAPQSRILLYIHGVCMHEQQLQQQGHDHGLAAAATLGYSPIHVRYNTGLHIAENGQQLSQLLEQLLADWPVPIEELVILGYSMGGLVARSACYYAEQLGHSWSQRLTKLVFLATPHHGSAFERYGAWLHYLLERNRYSALFGQIARLRSAGITDLRYGTILPHAQPTFDRFEQPAYRPDLMPLPAHVACYALAATRSEPQSLSNLRGDGLVAIASALGHDSEQPSHNLHIPTTNQAIVYATNHFGMIANQAAYQQILAWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S2</accession>
    <name>A9B4S2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3007"/>
    <dbReference type="EnsemblBacteria" id="ABX05645">
        <property type="protein sequence ID" value="ABX05645"/>
        <property type="gene ID" value="Haur_3007"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3007"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_473097_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3039-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026071">
        <property type="entry name" value="Glyco_Hydrolase_99"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13572">
        <property type="entry name" value="PTHR13572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16317">
        <property type="entry name" value="Glyco_hydro_99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735446" evidence="5">
        <location>
            <begin position="27"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="576" mass="65815" checksum="BFCDEEC1B0A06999" modified="2008-01-15" version="1">MRRIVILLGLILSLILIPSNSPSTSAAEPSRPVFAYYYGWWGSQTWYLDKIRDRPLELYESDRDSTMLNHIRQAKNAGIDGFICTWRYTCARLLQLAEQEGNFNVVFSVDPVADGTLNSTQAIVDNMREMAGLASSNAYWRWDGKPVFVFWNDTILPGGRGSLSDWTDLRSRVDPNRNQFWLGGGVNFSLLDVFDAIHFFDITWERKQGDAMISYSRNLREYNSSRNSNKPFVATVMPGYDDLLYRNGHFRDRENGNYYRAGWDTAINYQPKAIILTSWNEWYEGSQLEPSQAYGNLYLDISREKISAFKNNVPPIPDGFADTNFEKTWQRTDKPVQDGRTSRSWVWGPAIAKGQYEPYGGSTRLVQYFDKSRMEVNNPNGDRNQPWFVTNGLLVVEMIRGQVQIGDSSFEQRIPADEALGGDPRAINDVAPGYSSLRNVLASQPDKTGQTISTQLKRDATTSGITAPSVVTNAHYVSQTQHNIPDVFWNFMNQTGTVYENGRFVNDKQVVDWVFAFGYPLSDAYWMRAKLGGTETWMLVQAFERRILTYTPTNAPAFQVEMGNVGQHYRRWRYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4U4</accession>
    <name>A9B4U4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsH</name>
        <name evidence="9" type="ordered locus">Haur_3029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3029"/>
    <dbReference type="EnsemblBacteria" id="ABX05667">
        <property type="protein sequence ID" value="ABX05667"/>
        <property type="gene ID" value="Haur_3029"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3029"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_0"/>
    <dbReference type="OMA" id="QYGMTER"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="221"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="651" mass="71208" checksum="D3E67C8DC2ADFD82" modified="2008-01-15" version="1">MGENRFLRNSFVYLIIVVAALALFYQYINGSPGNTSEKSYSEILDLALQGKIAEIVQTEGQVEFRATTNDAPPTTYISRKNSTTESIEEILSQKAQDASKLAELKDPENKTAIAAPLENAAKVKFNPKSAPAWGGILGAALTFLLPTLLLIGFFVFFMRQAQGSNNQAMSFGKSKARMFTGDKPSVTFADVAGQEEAKQDLTEVVEFLKFPEKFAQLGARIPRGVLMVGPPGTGKTLLSRAVAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKRNAPCIVFIDEVDAVGRQRGAGLGGSHDEREQTLNQILVEMDGFDSNTNVIVIAATNRPDVLDPALVRPGRFDRQVVLDAPDMRGRVEVLKVHTKGKPLSEDVNLEAIAKLTPGSSGADLANIVNEAAILAARRSKKRIAMQEMQDATERIMLGGPERRSRVMTPKQKELTAFHEAGHAIVAKAMPGANPVHKVTIIPRGMAGGYTLMIPDEDQSYMSVSQFEAQIAVALGGRAAEELVLSDFTTGASGDIQQVTRMARAMVTRYGMSSELGPIAFGEKEELIFLGREISEQRNYSEETSRKIDSEVRRLVSEGHERARAILERNREVMNRMAEALIEHENLDGEPLRQLLDEVIKYNSNNGVYNDALPKQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X3</accession>
    <name>A9B4X3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3058"/>
    <dbReference type="EnsemblBacteria" id="ABX05696">
        <property type="protein sequence ID" value="ABX05696"/>
        <property type="gene ID" value="Haur_3058"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3058"/>
    <dbReference type="eggNOG" id="COG5267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026001_0_0_0"/>
    <dbReference type="OMA" id="GPANENY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3090-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="555" mass="62114" checksum="9FE905F92612126A" modified="2008-01-15" version="1">MSLSRRQLLLGAALGATGAVVHEDVGAAPLQPSTTEAMATPPFEVIALSRMAYGARSGDFARVRSMGLTAYVDEQLNPNFNNDTDCNTRIANATLRIVYAAGTGFPAMDEMRGLVTLNKTQPELWELRVHPANAERIRPIDEVVAANWIRAIYSKWQLFEIMTDFWHNHFNVWAYSDTRISSLWPYYDKSVIRANCFGNFRSFLEAVATSPAMLYYLDNATSRDGPANENYARELFELHTFGSQNYLNNIYDNWQEVPRDSQGRPIGYIDQDVYEAARAFTGWTVADGTGGIPNTGLFHYLDTWNDNAQKIVLANFLNANAGPQAHGKKVLDLVAQHPATIRNLCTKLCRRLVSDNPPSTLVDKAVATWTANYSAPDQIKKTIRTILLAPEFLSTWGGKIRRPNEVVAAYLRSTGAEVKPSAELFSWVTLAGYRMFNWATPTGHPDESGYWSSSNALLNTWNLLFHLQQSYFPPATFDLQGQMPGSVTTVRQIVDFWIMRMLGYQPSALVKTKLLKLMGQNGNLDQPPTGTANDVKLRLSSLVHMIGMLPEFYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z2</accession>
    <name>A9B4Z2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4180 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05715">
        <property type="protein sequence ID" value="ABX05715"/>
        <property type="gene ID" value="Haur_3077"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3077"/>
    <dbReference type="HOGENOM" id="CLU_151995_2_0_0"/>
    <dbReference type="OMA" id="ICIENDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3109-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025438">
        <property type="entry name" value="DUF4180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13788">
        <property type="entry name" value="DUF4180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4180" evidence="1">
        <location>
            <begin position="12"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13722" checksum="6D20D900FB061A23" modified="2008-01-15" version="1">MKLELVEKPPLRYLLGPQQQPVLQTIGEINLLLEHCFGEDCLNLALYAENLTPGFFDLSTREAGEILQKLRQYHVQLAIIVDLSQQAHSQYFAEMAGEENKQGHCYFCATLAKAEAWLAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B540</accession>
    <name>A9B540_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3541"/>
    <dbReference type="EnsemblBacteria" id="ABX06177">
        <property type="protein sequence ID" value="ABX06177"/>
        <property type="gene ID" value="Haur_3541"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3541"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049009_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3578-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731892" evidence="2">
        <location>
            <begin position="29"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="451" mass="49084" checksum="EEED4D402362FCDF" modified="2008-01-15" version="1">MVLRRILGIVTAAIAVVSLAVQPRSTAAAEPIKLDTQCFDVPGIINCLDDKFLSYWRSNGGLPVFGYPITAAANEVNPDTQQSYLTQWLERNRFELHPENAGTPYEVLLGLLGKERLTQLGREIEPREAGPVDGCLWFEQTGHNVCDQAGSLGFKSYWQSHGLKIDGLDNYARSLQLFGLPLTSAKSETNANGDTVVTQWFERARLEWHPSNPDEFKVLLGLLGKEIIDGRSQPTPPTPIDPCASTPDPVSARVRPAKCGEQGTEFSFDFYGFKASEEVGFWITNPDGINVGTRQTAKVGPNGSISGLPFDSRDATPGTWQFTMQSAYQSHQAIVYITVIAKAPQPTPNPSNCTSTPEPVSARISPAKCGPAGMVFIFDVFGFQPNEQVGFWITNPDGINVGIANTMNIGPEGAISGIEFPTDGFTPGTWQFTMQGTTSNHASIIYFTITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B577</accession>
    <name>A9B577_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3578"/>
    <dbReference type="EnsemblBacteria" id="ABX06214">
        <property type="protein sequence ID" value="ABX06214"/>
        <property type="gene ID" value="Haur_3578"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3578"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753928_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3617-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="230"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="40295" checksum="E947B44CE1A4CDFD" modified="2008-01-15" version="1">MEFRHYLRMLGRGWWLIALAALTGSTLALARAYVTEPEYRTRTRLLLSPNLARVDSGQELYSVTTLQNRTIVNTIAEILNSGSPFKETGSVLNLPPAEVLRYKNNAVTVPEANVLEVYVDGPDAPTTALLANSLAQRTIDFVDQKYPSYSLTVLDPALPSSTPQSPQPVRDTTLALILGAVVGAIIAIVQEQLKTPLEALRRRSTVDAVSTAFTRRHFDQQSKEALGRSSIASLGLVYLDGMQDVIDSMPAPVVQRVLRHAKNVLRNELRGNDIVGRWDNTTFSILLPETPEIAATRTLDRILNALDQPVETGIDDVVVKLTPYAGGATRRNNMAYAQLVEEAESALTRSYRSGEKNVLFSAVEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C2</accession>
    <name>A9B5C2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0095"/>
    <dbReference type="EnsemblBacteria" id="ABX02747">
        <property type="protein sequence ID" value="ABX02747"/>
        <property type="gene ID" value="Haur_0095"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0095"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_0"/>
    <dbReference type="OMA" id="WGLNENT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-96-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="28101" checksum="06391B938A6F87AE" modified="2008-01-15" version="1">MQTIQTLVVEDHPALRAAMVAGLQATKEITVIGEAGSGEDAIEWCAQHTPQAILMDVALASELNGIQAAVIIRREHPRIPVVFYSIQDDDAYYRDFQRSGILSHYAYVRKSNYLLPAMVAPLLRDAFQGRAFIDPDIASRVQEVRHRDEQSALDLLEPAEREVMTLVAHGFTNDQIAQRLGFRDARAVSRINGQIYTAWGLNENTTDEKVARTRATIIFHERQLIVWDEEGRGRAYMPDGQWQARWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D8</accession>
    <name>A9B5D8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0111"/>
    <dbReference type="EnsemblBacteria" id="ABX02763">
        <property type="protein sequence ID" value="ABX02763"/>
        <property type="gene ID" value="Haur_0111"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0111"/>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120387_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-112-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15121" checksum="A725C24C4159D7FE" modified="2008-01-15" version="1">MQLELITSDQQPTFEHLLSTVGLGNEGLATAQAYGWWQDGKLQAGGALEIYGELGLLRSVAVRPDQQNQGLGAALLDALEQQARQLGLQTLYLLTTSAAKFFAAHGYQPIERAEADSRLHASVQWGSICSSATLMVKHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G3</accession>
    <name>A9B5G3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0136"/>
    <dbReference type="EnsemblBacteria" id="ABX02788">
        <property type="protein sequence ID" value="ABX02788"/>
        <property type="gene ID" value="Haur_0136"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0136"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="75"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="776" mass="88873" checksum="F2EBE5496AB1B7DF" modified="2008-01-15" version="1">MRGNSHVRFLGGGSVVIRSCYPTDHLPERSQLPPHSVMPYQPLSDFVGREAQLYQLAQAMLRSDPTLITPTALATGMGGIGKSSLALEFAHRYGSYFAGGVFWLYAATNETLQASLDRCWDSLKPDEWRYEVKPETRLRVVRELFNQPIPRLLIFDNCEDPALLTAYRPQASSGCQLLVTSRRSQWQGTNLITLDTLPPLESRQLLQQLAAQPNINNYLSDTDADQLAELVGHLPLALHLVGSSLKFYFRKPAAEYIAALQNQRIASLQAMVKPTSKLHQNTINNFWSVRDTVEVSYGLLPAELGQACRRLLLMMAYCAPNVVIPWELLQAASGYDDDSLTEYLWELTQAGFFNDPTQPRLHPLMADVIIDLDAANEPENYRSLEQALIMLSNRYHDQWAMREIEMLLPHLEYSDRQASQHPDYAGELGYQAGLCLYRQGKYVDAEHIYREVLSTQNQLFETENPIILNTKHALADVLGDQGLLQEAEQLFNEVYRLRKKVLGQYHPHTLKSKKEYATAMFLRGNYADAEQILREILTIQEQSLGKEHWDSLLTKHNLASIRSKQGYYALAERMYREILKDQEQIFGVNHPDTLATKRQIANNVGYQGRYAETERIYREVLPIYELILGLNHPYTLTTKHGIAWALNGQGLYKQAEYMYREVLLICEQTLRINHPEIITTKHNIAWILSKQQHYLEAEVIYREVLEIREQSLGTNHPDSLSTKYNLAATLYHQSCYREAELLFDQVLSIREKVLGTQHASTQATQEWLELVRSKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G4</accession>
    <name>A9B5G4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0137"/>
    <dbReference type="EnsemblBacteria" id="ABX02789">
        <property type="protein sequence ID" value="ABX02789"/>
        <property type="gene ID" value="Haur_0137"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0137"/>
    <dbReference type="eggNOG" id="ENOG502Z8X1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107033_0_0_0"/>
    <dbReference type="OMA" id="FGIIWVG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-140-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="23422" checksum="B2266AE0B4541476" modified="2008-01-15" version="1">MHSTQKWGGIAALINGFAYIIGIGIVFTLLAPFLEASQAEKISFLIEHQNLMALWYLIIYLVAGVWMVPLAIALHHRLQQAHPLLIQVTTAMGIIWATTILSSGMLLVNNIKIIADLQQQNPEQTLAVSTAISAVASGLGGAIELPGGVWVSLISIAALQTKRLPKALNYLGLLIGASGIAMTVPAIAAVGTLFGIGMIGWFLWVGVVLVRTKNIEHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I0</accession>
    <name>A9B5I0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0153"/>
    <dbReference type="EnsemblBacteria" id="ABX02805">
        <property type="protein sequence ID" value="ABX02805"/>
        <property type="gene ID" value="Haur_0153"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0153"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033976_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-156-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="448" mass="49281" checksum="69A4F12E8EA4E079" modified="2008-01-15" version="1">MRVGLDFGTTNTTAAIYDGANVSLVPLDSVAANPNVLRTALFITPEGQQRIGRAAINAFTEGNVGREIVYERRYLGTVTNTYAGVGTITQAVEGLVDSNPPGRLFQSIKTMLRDPSYIKTNVFGQETTLEELIAKILRAIRREIERFTGEKISAITVGRPVHYASTAEGDALAIRRMREACELADLPNVSFMPEPVAAAHAFAASQRERRNIIVFDFGGGTLDVTVMAIDGAKRQVLATDGVPIGGDVLDSKIVTGALRQYFGDGARLGPRKLPLPAALMEHLDNWQNILEMHTPKMLDIIEESVRTSDKPKELKALRSLVRENYGLVLYEHAEEAKRRLSSERQVEISMHVKDIDFDHLLPRFEFERLVGPEARAIGDCVDRTVRAAGLSHEQIDVVLRTGGSSRIPRFIKLLADRFTEDRLREQDPFTSVGAGLAVAAYEGLGEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T3</accession>
    <name>A9B5T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Death-on-curing family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1673"/>
    <dbReference type="EnsemblBacteria" id="ABX04316">
        <property type="protein sequence ID" value="ABX04316"/>
        <property type="gene ID" value="Haur_1673"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1673"/>
    <dbReference type="eggNOG" id="COG3654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115697_7_0_0"/>
    <dbReference type="OMA" id="IASHDRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1697-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="15569" checksum="AE184C2FA3D53C10" modified="2008-01-15" version="1">MKWHMHYLKREDMLDIHGYLVERFGGRLGLNSLDRLIGLVVSQTQTCFGEELYPDLPAKIAALSYTFIKNRPFRAGNTATALLVALRLAHINDQTIEDIEGLSHELAAAARSERSQEQLLQWFNDHLIPGSLTIQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B691</accession>
    <name>A9B691_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06302">
        <property type="protein sequence ID" value="ABX06302"/>
        <property type="gene ID" value="Haur_3666"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3666"/>
    <dbReference type="HOGENOM" id="CLU_1382467_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3705-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="197" mass="22694" checksum="79705715FD82A826" modified="2008-01-15" version="1">MAMRFCHYTIENHIDRIEPTFGYYEMAMLSRLKPTNYLIGAYSMANSDVEEIAMQCPRCQQKVALHINQCPNCKRMLKPLIMRQHIALSTQQRQGLRQNIVTLLVALLFLIGIVVTFHVALKQVSGLIWPIIGLMIAVVGFYLVRLLRDWISGQVLVQIDQLQALQEVRRRGGRRFYGDFRAIGSQQLQQTSLRTCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B1</accession>
    <name>A9B6B1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYZ2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3686"/>
    <dbReference type="EnsemblBacteria" id="ABX06322">
        <property type="protein sequence ID" value="ABX06322"/>
        <property type="gene ID" value="Haur_3686"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3686"/>
    <dbReference type="eggNOG" id="COG1705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1298372_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3728-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="1">
        <location>
            <begin position="95"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="23360" checksum="57EA18EF2B0C4383" modified="2008-01-15" version="1">MLYGFDDFSSRRRTFFLIALAAALVWMIVQFRGSSNVFYSSMSAPGRPAQSASGNLAGSFGAIDGDSILGVPTISAAKIDQVLSSYNSPATGKGQVIYDMGIKYGIDPAYCLAFFIHESTAGTQGVARVTQSIGNIRTTAGYEDYQGYRKYPSWEAGIEDWYKLIRNLYIDEWQLTTIQDIIPVYAPPVENDTNHYVETVRTLVNSWRAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J5</accession>
    <name>A9B6J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0246"/>
    <dbReference type="EnsemblBacteria" id="ABX02898">
        <property type="protein sequence ID" value="ABX02898"/>
        <property type="gene ID" value="Haur_0246"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0246"/>
    <dbReference type="eggNOG" id="ENOG5032RE1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094589_0_0_0"/>
    <dbReference type="OMA" id="FAANTAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-249-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="92"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
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        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="26149" checksum="972CB5C8675242D8" modified="2008-01-15" version="1">MIATKAYPTTNQTERSMTSTYRWAAGLLFAQFSVFLVAFLVLSSAIDWPASLDNPASQSLPLILQERSAVALGYTAYFLSATMLIPIALLLWQILASESALMRVTAGLGMLAGFAKLLGIGRWLLMMPTLAEQYSATSDPNLRATIEVIYTSFNNYAGGVGEQIGVALFGGLWTAGVALTILRQTTLPRWLGYSGLIAAASVLVSLIELYGISAGPMLTVSGSLWQFWLITLGGMLLRHKSKA</sequence>
</entry>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1688"/>
    <dbReference type="EnsemblBacteria" id="ABX04331">
        <property type="protein sequence ID" value="ABX04331"/>
        <property type="gene ID" value="Haur_1688"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1688"/>
    <dbReference type="eggNOG" id="COG3871">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091428_1_1_0"/>
    <dbReference type="OMA" id="NVNVAYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1712-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
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    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrid_ox_like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18458" checksum="8351A977972FDBE5" modified="2008-01-15" version="1">MQDQTTTQQNISKVAEQLKGFKLAMLTTVASDNSLHSRPMVVQQKEFDGDLWFMTGRDSGKIAELSQSKQVNVAFVDVDDSRYVSLSGTGQIVDDRAKIKELWTPLAKAWFKDENDPNIVLIKVEPQIVEYWDTPNSTFVQVAGFLSALVTGERPEIGEHGKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R5</accession>
    <name>A9B6R5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1731</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04374">
        <property type="protein sequence ID" value="ABX04374"/>
        <property type="gene ID" value="Haur_1731"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1731"/>
    <dbReference type="eggNOG" id="ENOG503317X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1757365_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1758-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025597">
        <property type="entry name" value="DUF4345"/>
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    <dbReference type="Pfam" id="PF14248">
        <property type="entry name" value="DUF4345"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15289" checksum="D5B88B74B76E5128" modified="2008-01-15" version="1">MQRISVVGLKIVLVLVGLMSLYISLDFGLGGFETLGWQGAPPHVAEPGNLRYAVHDSHFRFLAGVFGTLGVSILLAVRDLAKYSLLLQTIFTAFIVGGVLRFSANNHEILLSGELLLALIAEIGLMLGLHWWLHQALKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B743</accession>
    <name>A9B743_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3274</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3274"/>
    <dbReference type="EnsemblBacteria" id="ABX05911">
        <property type="protein sequence ID" value="ABX05911"/>
        <property type="gene ID" value="Haur_3274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3274"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464431_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3309-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734600" evidence="1">
        <location>
            <begin position="28"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="63762" checksum="5B6C4678EE12455A" modified="2008-01-15" version="1">MGRRWLKLVALCAIFLLGSIWLPAASAETSVVTLNDLALGTTSSISNDTMRIVHNGLAYFTANDQSNGWTLWRSDGTAAGTFRLTTAQQTNIIPQYLVGYGAYAYIATYTHTDGYSIWKTDGSPNSISKVVSFDSSSVTTGYVKISLMQVAQNTLYFFFAYESMVEVWKLDQALQPVRIKAFRASAMQFTVSSIDRLVEFNGAVYFLVSTTDIPFWGYFSDLWRTDGTPEGTYSVQVIDGRKYARVQGPVVAGGKLIFNSLLDGVVASNGYPNGSEPLFDTIEDGDAPMQLVSVNGIGLLTRYHGHRLWRTDGTVEGTYPIDVNPHGPDNLIFGPVVGNYLYFTAEHPSYGRELWRTNGTLAGTSLVIDGIAGPTSSNPINFATVGKQLYFTATNSQGGVQPWKLDCVGANPQMIGPIDSISANANPGMYLETPQGIVFAANTPALGHEPWLYRESGNTWLKSNAVVATASDQVAAIPVTIGNDGTIMQQTLELTLILTDRVEYLSDTSGITPTIQANSYAWKLDRIAANCNEHSFVVYVKLPSFSLNQHRPFTLQLSGMAPGDSANDNQVNGQLVVGTPLFLPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N7</accession>
    <name>A9B7N7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioesterase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1772"/>
    <dbReference type="EnsemblBacteria" id="ABX04415">
        <property type="protein sequence ID" value="ABX04415"/>
        <property type="gene ID" value="Haur_1772"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1772"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_6_3_0"/>
    <dbReference type="OMA" id="WCYGCGR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1800-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17156" checksum="1779AC21E75C9F03" modified="2008-01-15" version="1">MVSTTQPAFQDQLQGNHCWGCGKDNPHGLQIKSYWDGAEAICHWQPQPWHCASPTHVVNGGIIGALIDCHAIISAMALAAQQAGVALSSPTPIWYVTGKLEIAYHKPTPLGPSLELRARFEVQNERKTLVTCTLNAADQLCATGTVLAVRVPSEWMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B818</accession>
    <name>A9B818_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3315"/>
    <dbReference type="EnsemblBacteria" id="ABX05951">
        <property type="protein sequence ID" value="ABX05951"/>
        <property type="gene ID" value="Haur_3315"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3315"/>
    <dbReference type="eggNOG" id="ENOG5032JBT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276803_0_0_0"/>
    <dbReference type="OMA" id="GQRILWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3352-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018700">
        <property type="entry name" value="DUF2204"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09970">
        <property type="entry name" value="DUF2204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20327" checksum="3D3BEBBD042707D6" modified="2008-01-15" version="1">MSLIAGNLAVVQKLLDGAAMSWGIYGGAAAHFYGSRRPINDIDIIVPANTLSEIARLLQQGQKAVQYDGGRILWRGIILQEDLTIRLNGNIYPFVLDPPMIERLQRKPLLGSRVLFLAPEDVLVHKLILYRGPEQQRFDIVDCEGIIKRHQLDLEYLRQRLQTSNATTIVTPRIADMGVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B831</accession>
    <name>A9B831_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3328"/>
    <dbReference type="EnsemblBacteria" id="ABX05964">
        <property type="protein sequence ID" value="ABX05964"/>
        <property type="gene ID" value="Haur_3328"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3328"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_30_0_0"/>
    <dbReference type="OMA" id="VGNDWQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3365-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="18122" checksum="9F01EB0B4869F0EE" modified="2008-01-15" version="1">MESIVHIVLALLRRENQVLLVRQQGQNGSYWGIPGGKVELGEHWLEAFAREVREETGLVAAANTLAYMSQVYLVGKEQTVVFCAFEGTTEGEIAINDPDNEIEECAWFDLHEIPKMIQSLRWPSTRLPLLDYLAGNVEAGRVWAFRSNEDNSEQYLLQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B859</accession>
    <name>A9B859_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide pyruvyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3356"/>
    <dbReference type="EnsemblBacteria" id="ABX05992">
        <property type="protein sequence ID" value="ABX05992"/>
        <property type="gene ID" value="Haur_3356"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3356"/>
    <dbReference type="eggNOG" id="COG2327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039510_0_1_0"/>
    <dbReference type="OMA" id="IMQQLGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3393-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PS_pyruv_trans" evidence="2">
        <location>
            <begin position="13"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="435" mass="48435" checksum="C90EB36D3C8FC21C" modified="2008-01-15" version="1">MKVLLLNAHSPQNAGDLALLEQSLAHLRAAFPHADLSYVINQPDPPQWLPADVPYILSIHEHKTNLIKDAPKPRRKWLMLGLAIWLVGISLIYRWTGIKLKPAKTSDWRELLEHYFEADVTAAIGGGYLYATKAFDLNYIWVWLGVALPVLMGKPLVMLPQSFGPVTGKINQLLLAWLVNRSVQAYAREERSQHYLYSIGVNQSVQVVPDVAFNCPTVEPAQAEHYLARWWQPAKRPALVVGITAMDFGIQHPGSGFSHGQRYEQALLDLIQHIGQCDDVHILLFAQCVGASEAEDDRVVARRLIAQLPATTPITFIDDRLQPAMLKQLYSQIDLLIATRLHSAIFALSTATPSFVIGYLHKSAGVMHMLGLADYQIPIESIDSSNIISAFEQTLAARGSIKTMMRSSIPALQSQLERLPKQIRAAVGDWLRGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B873</accession>
    <name>A9B873_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-superfamily hydrolase, subfamily IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3370"/>
    <dbReference type="EnsemblBacteria" id="ABX06006">
        <property type="protein sequence ID" value="ABX06006"/>
        <property type="gene ID" value="Haur_3370"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3370"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_1_1_0"/>
    <dbReference type="OMA" id="AFEYICR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3407-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="27812" checksum="7DE27C4C37C5A741" modified="2008-01-15" version="1">MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARLARIGLPLEIEDIYTSALATAKFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVVIGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGILPACGAVVALIRAATNAEAYFVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAERYPYRPTAIIESVAELFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B887</accession>
    <name>A9B887_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3804"/>
    <dbReference type="EnsemblBacteria" id="ABX06440">
        <property type="protein sequence ID" value="ABX06440"/>
        <property type="gene ID" value="Haur_3804"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3804"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="VLCEGTM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3846-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29164" checksum="5F6E383F792003BD" modified="2008-01-15" version="1">MPNVLLKTEHLSRSFGGLQAVRDVSIAVEEGSFHSVIGPNGAGKTTFFNMISGAIKPSSGKVFFAGNEITGLPLHRMIHLGIGRAYQITSLFPSLSVAENVRLAAQARGRDTFKFWQHSDRFERYHERAQAALKLVGLRGVEQVLASALPHGDKRKLELALLLASEPRLLLLDEPTAGMAANQVPELIEIIQQLRQSGQHTIILVEHRMDVVMSISDQITVMHGGSVLAEGTPQAIAADPRVQQAYLGELYDDVLTQPHEVAHDTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A6</accession>
    <name>A9B8A6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3823"/>
    <dbReference type="EnsemblBacteria" id="ABX06459">
        <property type="protein sequence ID" value="ABX06459"/>
        <property type="gene ID" value="Haur_3823"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3823"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_2_0"/>
    <dbReference type="OMA" id="ILIFEAK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3865-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28247" checksum="D2124D71ABA9457F" modified="2008-01-15" version="1">MLTSKHNPAIKQIRALRQRREREATGLFFIEGIRNVTEAVQAQAPIEQLIVAPDLLRSQFAQDLVEQQRQQAIPILEVSGEVFASLSSKDGPQGLAAVVRQQWASLADVRPDQGLCWIALNAISDPGNLGTILRTGDAVGAAGVILLGDCTDPYDPATGRASMGTLFSQRLVKATWAEFSQWFGQSGFNLVGAADSASSHYRDYAYPQPLILLMGSEREGLDAEQQAQCQALVSIPMRGQADSLNLAVATGVLLYEILAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A9</accession>
    <name>A9B8A9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3826"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06462">
        <property type="protein sequence ID" value="ABX06462"/>
        <property type="gene ID" value="Haur_3826"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3826"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_4_0"/>
    <dbReference type="OMA" id="QPSLWEG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3868-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="212"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="409" mass="44048" checksum="F223D89B6E690DE1" modified="2008-01-15" version="1">MRILMIASSFPKYPGEMTAPFIEEIAAAVVERGHEVHMLLPDHPELKRGDQVRGMQIHRYRYAPHPSLNVWGYAGALHNDVQMRNAALLVAPLAVASAWRTMAQLTAQQPFDLIHGHWSIPNGFPAWLLARQRKLPLIISTHGSDVSVAERTAPTGWINTAIMRYASAITAPSSDLTTRAAALGAEPAKLHVLPYCVDAVDFRPDPAVGAAFRQQHGLDTATPLLFTVGRMVEKKGFRYLVQAFAQVLAQHPTAKLMIGGYGPGLEQLMAQAADLGIGEAVLFPGAIGHDLINSALNAATIFILPSVRDRSGNVDGLPNTLLEAMGAGRPIIASKIAGVPGVITSGEHGLLVAPAQPQALSAAINDLLNQPERARLLGKAARLRVETELTWNRYAARLEQLYTAAIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B992</accession>
    <name>A9B992_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07906">
        <property type="protein sequence ID" value="ABX07906"/>
        <property type="gene ID" value="Haur_5279"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5279"/>
    <dbReference type="HOGENOM" id="CLU_655173_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5341-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="48440" checksum="EB9E3DED2903A04B" modified="2008-01-15" version="1">MGIGDGRDYPSLSDGELNRIREEVRRSGYPLEQRVSHICHAALDGPTRLFPPGSITYREDGVYYSPDPVSQPWQRIDLPFPAYPSWDMDNYSYGTKRTIYRETRQTDHHMAAVWREVDQVLSVRSTAWVCDEPVDASLAVEAQALIECKHRERRLLVGIHDPQSSGSSSPIFSPLARTRLLHTVGQAIPDPLYGLPWVTPLLLESRGENEAKRDWRTNDEKLIYAATGSLYDYLIHQWQPWTETMIHPFLVESGIWSILAPRLDDPWFSLQRWIATELQPAWWEAFNAQHAQWHIVPPIQLALPILCVDMPLYQTTIDQDGQVQALVPIPAMVVEERMQDWPGRLNQVLYDVKPRFDTYRSAPVVVVHVDHLMPILIRLSEWINAWYAALEHHEHDPVLVQTWPLEVALWEAYYHHTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUX7</accession>
    <name>A9AUX7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3931"/>
    <dbReference type="EnsemblBacteria" id="ABX06565">
        <property type="protein sequence ID" value="ABX06565"/>
        <property type="gene ID" value="Haur_3931"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3931"/>
    <dbReference type="HOGENOM" id="CLU_1494294_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3973-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="19223" checksum="5165757549314F0E" modified="2008-01-15" version="1">MTDLAQYHPLLVHAPLMLLPTAILLRVLHLIWPKAGFRLTAIVLLVAGIGLGILSEESGEAAEHVAEARSANVEDIQATGTIPEMFGEGSLLETHASLAETTVIVFMLLLISEAMLLFLSQPLFARWRGSFSLPSGLHKPLEIGWVVVGVAAIALVVLTGHYGGKLVYEHGIGVSLSAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV11</accession>
    <name>A9AV11_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3967"/>
    <dbReference type="EnsemblBacteria" id="ABX06599">
        <property type="protein sequence ID" value="ABX06599"/>
        <property type="gene ID" value="Haur_3967"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3967"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_29_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4009-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1449"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="3000"/>
            <end position="3075"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1484"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3093" mass="330089" checksum="1EA71C0E5B3775E4" modified="2008-01-15" version="1">MTGSTATNYNGAVAIIGITGRFPDARDVAAFWQNLVAGVRSIRSFTDAELLAAGVDPEVLNDPNFVKHGTRLDDIELFDAAFFGYTPREAEVMDPQHRLFLECAWQALEQAGYDPEGFRGAIGVFAGSATSTYRGNNLHTNREIAEAAGGLQLAVGNDVDSLASTVSYKLNLRGPSVAVQTFCSTSLVAVHMACQSLLTYECGLALAGGAVIAVPQGEGYMYQEGGILSPDGHCRTFDAKAQGSVMSNGVGVVLLKRMTDALKDGDTIYAVIRGSAVNNDGIRKVGYTAPGLNGQSSVITIAQSRAKVAPETVSYIEAHGTATPLGDSIELAALIKAFERGAPRKQSCALGSVKPNMGHLDRASGVTGLIKTTMALHHRQLPPNLDFEAPSPDIDLANSPFYVNTQLREWPANGAAPRRAGVNSFGLGGTNVHVVLEEAPAPAPVAPARPAQLLVLSAKTATALEAMTDNLAAYLAGAPVDLADVAFTLQVGRAGFNHRRILVGDSVADVRAALVAKDSRRVLSATQTGRNRPVAFVFPGVGDHYAGMAGTLYATEAVFREAVDQCAELLAPRLGQDLRAALYPADQPAATAAHTLFAATAASSRVAGALHQTALAQPAVFVVEYALVQLLASWGIRPQALLGYSLGEYVAATVAGVLSLEDALTLVAKRAQWIQAQPHGAMLAVSLGVEAIQPYLNTEVALAVVNSPMTCVLAGSQPALAALAERFAAADVASRWLETSHAFHSPMLAPVAAELTALVRTLRLQTPKIPYISNVTGTWITDAEATDPGYWARHMVETVQFADGVGTLLADAQLALLEVGPGQALGSFIRQHPTCGRTRFGQIVATLPGATEPQRDLIALLEGLGRLWLAGVPVDWAGFHGGAARRRVPLPTYPFERKRFWIDAPKREWAAANQPATVGKRADIADWFYRPEWAPAALNAPTNDSKQRWLIFVDAMGIGAGVRQRLAEHGHEAVTVTIGEGFKRLDTHHYELAPTRLADYLDLIAAIQGQDPLPTHVLHLWSLTPLAGIKSGAARFAAAQDYCFTSLLNLARAFEAQVITDSIHMLVVSKGMQAVDPSDIPDADNATLLGACTVIGQENTSIIVRSVDLDVDLDARHLDGYAAGLIAEGQSGSHDLHVAYRDGQRFAERYVPLRLEALSQPILRPGGVYLMTGGLGGVGLILAEHLARTAQAKLVLVGRQGLPERAAWDAWLREHGADDATSQRIQRVRTIESAGGVVEVVAADVADPEQMRRAVAIAEARFGPINGVLHAAGISDDTAFRLIQTLEQATYAAHFQPKVYGLYALEAALGDRPLDFCVLCSSVSSVLGGLGFAGYAAANCFIDAFTQRHNRTHAVPWVSVNWDTWHLRAGQHDVTGLTVAQYEMSPAEGAAAFERVAAARGHSQIINSTGDLDARIRQWVRLESIRNDAAVAPAPASNGRPELSTTYVAPIGEYEQRVSAIWQHVLGIDEIGLHDNFFDLGGNSLIALQLIARLKKEFKTHISAVALFEAPTVSTMAQYLRPEVAPEEHVDQERLLIEHRREQTRQTVQADGIAIIGMVGRFPGASSVEELWQNLHNGVESTTHFTDAELLAAGVDPMQVYHPDYVKSRPILQEDITLFDAAFFGYTPREAEFLDPQQRLFHECAWEALEQAGYDTQRYPGLVGVFGGTNTNAYLNRIARDPRSDGHITEIITLENDKDALATNVAYKLNLRGPSFAVQTFCSTSLVATHLACRSLRHGECDIALAGGVSVRVPVNTGYLYEEGDQVSPDGHCRTFDANAGGATFGDGVAIVVLKRLADALADGDTIHAVIRGSAINNDGGLKVGYTAPSVVGQAAVVQAALADANLAADAISYVEAHGTATKLGDPIEVASLTKAYRTTTDKVGFCAISSVKPNVGHLDRASGATGLIKTVMALKHNVIPATLHFQTPNPEIDFASSPFFVPTALTPWTRNGTPRRAGVNSLGVGGTNAHVIVEEAPQVGPSGPGRAVELLVLSAKTATALEAATTNLAAYLEEQPMVNLADVAHTLQVGRRVFEHRRVVVARDVADAVGLLRSGDARRVLTLAQKPTSRGVAFVFPGVGDHYIGMAEGLYATEGVFRATVDRCCALLTPLLGSPIRKEIYPDGGVPAQTGVDLRAMLRQDATPRSAGRLHQTAWAQPAVFVVEYALVQLLASWGIRPQALLGYSVGEYVAAAVAGVLSLEDALTLVAKRAQWIQAQPAGSMLAVSLSAEAIGAYVGGAVALAVVNSPMTCVLAGPQAALEAVKTRLDGDEVASRWLETSHAFHSPMLAPVQAELTALVRTLRLQAPRIPYISNITGTWITDAEATDPGYWARHMVETVQFADGVGTLLADAQLVVLEVGPGQALGSFIRQHPACGRDRFGQIVATVCGMTDTSDDLEVLLSALGRLWLHDVVVDWASFRGSEVRQRIPLPTYPFERQRFWIELPPNPRGDSGRKVRRFDAGDWYAVPSWKRAVAHDELIDGAAGLGDQGSWLVLADGEGLAAGLTAWLEERGQTVITVTPGAAFAQHSATAYTVRAGSREDFTALLQTLERHGQMPSRIVHAWLATPKVGAAQLDDVGLAESLDLGFYSLLALAQALGEQDIEWCEINVLTSEMHDINGREELNVAAAAVIGPCKIIPVEYPNLTARSIDILLPASPAERATLVAQIGAELATPPTGDLVAFRGAHRWVQMMEPVALPTAPASHPRLRTGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSSLPDRATWPALLERDGAEQGVGRRIQQVLDLEALGAEVLVIQADVTDAVAMARAVAEAQARFGTIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPLDFLVLFSSVTSATGGGPGQVAYCAANAFLDAYARKHATDHGRTVAVSWGEWLWDAWSDGLQGFSAEDQLRFRAYRRTFGITFDEGAEALRRILACRISHLFVTTEDVVAMFEDSKGSALQRAARQEDAAQRYPRPEVSTSFVEPQSELEQQVSAIWSEVLGIAPIGVNDNFFDLGGNSLIGIQIVTRLRRTFQVALPLTILFDAPTVEEMSIAIEMMLIDAIEHSSESAAESVSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV37</accession>
    <name>A9AV37_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0464"/>
    <dbReference type="EnsemblBacteria" id="ABX03115">
        <property type="protein sequence ID" value="ABX03115"/>
        <property type="gene ID" value="Haur_0464"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0464"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_996925_0_0_0"/>
    <dbReference type="OMA" id="NALYYQW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-470-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="31985" checksum="E2405B81AA18F834" modified="2008-01-15" version="1">MRRQKPLDWATLGPIAVLLGLLLLIVNQLNQPKNQYAPLSAYFNDAAASVPQSQLTPLPPTTLQAIEQSNAAGSSNQIDLVLEAELYQDQSNELASELQIALDYVQERTNIRLAERVTVVISQDAQCGFHGVTYSDVRVIYIYSCAGVARSRVVNIAAHEFVHQLEQDRYGAAHLSTDLVLSEGFATWGAGRYWLGSASDFTSFARDYQANGQALPLATHYAGVGIDGMNVLYYQWASFVDYLINNYGREAFDQLYISGGERQPGAANYAAIYNRSFGLLEAEWRQTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN8</accession>
    <name>A9AVN8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Capsular exopolysaccharide family</fullName>
            <ecNumber evidence="3">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.10.2" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4006"/>
    <dbReference type="EnsemblBacteria" id="ABX06638">
        <property type="protein sequence ID" value="ABX06638"/>
        <property type="gene ID" value="Haur_4006"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4006"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052027_2_4_0"/>
    <dbReference type="OMA" id="NPVSEQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4048-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="215" mass="23323" checksum="C86496D61E169C4A" modified="2008-01-15" version="1">MALDLITLRDPRAAAAEAYRTLRTNIQFSSIERKLHTILVTSSVPDEDKSSALANLAVTFAQAEQRVIVLDCDLRRPSLHSLFGVSNERGLSQAMNQNSALPIVKTEIDGLQILPAGETPPSPADLLSSKRLDSVLRDLKQQADIVLIDAPPVLAASDAALLATKVDGVVLVTKAGKTRRDSAREAVALLQRVNAHIVGVILTNAKLERERYARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT2</accession>
    <name>A9AVT2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4050"/>
    <dbReference type="EnsemblBacteria" id="ABX06682">
        <property type="protein sequence ID" value="ABX06682"/>
        <property type="gene ID" value="Haur_4050"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4050"/>
    <dbReference type="eggNOG" id="COG4639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119557_0_0_0"/>
    <dbReference type="OMA" id="RINLDML"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4093-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017101">
        <property type="entry name" value="P-loop_ATP/GTP-bd_All4644_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037081">
        <property type="entry name" value="P-loop_All4644_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="150" mass="17480" checksum="AB7F686B7A77EC6E" modified="2008-01-15" version="1">MQPQATLLIGLQASGKSTFYVQQFLHSHVRINLDMLRTQHREQTLIACCLELRQSFVIDRMNLERNRRSGYIQAAQAAGFRIEGYLLESNLAACLERNRQRTGKQHIPELAIRGSFKKLELPSLAEGFERLWYVRQLPAHQFQVTPWEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV1</accession>
    <name>A9AVV1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="7" type="ordered locus">Haur_4069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4069"/>
    <dbReference type="EnsemblBacteria" id="ABX06701">
        <property type="protein sequence ID" value="ABX06701"/>
        <property type="gene ID" value="Haur_4069"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4069"/>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2069883_0_0_0"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="12685" checksum="F329997FAD8DA25A" modified="2008-01-15" version="1">MSSREPASYARAVYDSLVAALTAEGQEQLLPAVLDELVQLARSGGPTAAEVTSAVELSAEQRTKIEKDLKARYGALLDIAYKVDPEILGGLLVRVGDKVLDSTLRQRLNAVQRNMMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW49</accession>
    <name>A9AW49_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03287">
        <property type="protein sequence ID" value="ABX03287"/>
        <property type="gene ID" value="Haur_0639"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0639"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_2_0_0"/>
    <dbReference type="OMA" id="WSQAGPN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-648-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="258"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="45463" checksum="8C58414D3079CEAD" modified="2008-01-15" version="1">MSKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALNRVEEQLIELSNGCICCTLREDLLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDESGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAIDEADERTLVDLLIDQIEFCNVLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPGWLAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPETAGLLSQAGQNCRVEPAGQWWADSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDFDQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW66</accession>
    <name>A9AW66_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2076"/>
    <dbReference type="EnsemblBacteria" id="ABX04716">
        <property type="protein sequence ID" value="ABX04716"/>
        <property type="gene ID" value="Haur_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2076"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037483_0_0_0"/>
    <dbReference type="OMA" id="NTIFCYI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2104-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="373" mass="40556" checksum="8EC69C17E645FD28" modified="2008-01-15" version="1">MQSYDVLVVGAGAAGVGIGCALQELTLTPNQWLIIDRTAVGSSFRHWPCEMRLITPSFPGNDFGVIDLNAVTPHTSPALSLAAEHPSGPDYARYLCSLAEHFELPIRTDVSVTAVEPADDGFIVRTTSEPLHARLVIWAAGEFQYPRTTGFCGAEQCLLASTVSSWNHIMGTDPIIIGGYESGMDAAIHLARRGMAVRVIDAGTPWDTIDTDPSRTLSPYTQERLRALPNGALTLIGETRVERVVTVAEGYYVFTNHHPVPLFSAMAPILATGFAGSLSSPAIAPLFARRDDGYVVLTTEDESTITPGLFVVGPNVRHDDLIFCFIYKFRQRFAVVARAIGQRLGLPTDGLDWYRERGMFLDDLSCCDTTCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW75</accession>
    <name>A9AW75_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2085"/>
    <dbReference type="EnsemblBacteria" id="ABX04725">
        <property type="protein sequence ID" value="ABX04725"/>
        <property type="gene ID" value="Haur_2085"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2085"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2113-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="38"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="27651" checksum="3FB25B94FA662CCB" modified="2008-01-15" version="1">MLVYQSQKFKSCCHVTIRVTADCYARWIEATATKGGCFIVTVDGYYEAKDKTIDKLFQFYHSDYVDDQNFDHYAAERLRAADTLILSGRTSFLGNKQYWTSVPNDPNATPIRRELADLYHRTDKLVISDTIRLPDLAPWKNTRIVSIADAPNEIRTLKEQPGRDMLILMGRVLWNALLVHRLIDELHLTTFPIIAGDGIPLFNGRPPIALKLIHSRQWQGSGNSLACYRVDYESALSEREAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD1</accession>
    <name>A9AWD1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2141"/>
    <dbReference type="EnsemblBacteria" id="ABX04781">
        <property type="protein sequence ID" value="ABX04781"/>
        <property type="gene ID" value="Haur_2141"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2141"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019123_3_0_0"/>
    <dbReference type="OMA" id="FNVGQTS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2169-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021908">
        <property type="entry name" value="DUF3520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022156">
        <property type="entry name" value="Uncharacterised_YfbK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12034">
        <property type="entry name" value="DUF3520"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12450">
        <property type="entry name" value="vWF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="267"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="610" mass="66881" checksum="0FB08654381BC47F" modified="2008-01-15" version="1">MRSIRKSKFEEQSRNLQIQKGTKEEQATFDRCGPQCLINLTKKEDVMRLKRSSIVLIALIISACGGEASLPTINPQPQRPAPQPRPTSAADDQSAQWPTAEATSVAPAPQPMPTQAADAGQPVPNPAAGKPLVDTWELPTQPIDPNPNYAYEQDQEIFDSMYFKNYGTNPFVRTETDPLSTFAMDIDSASYSLMRSSINQGLLPPADSVRVEEYLNAFDYEYPQPEDGDFAIYSEVAPSPFGGPNYELVQIGIQARSIEVADRKPAALTFVIDTSGSMAQDNRLEMVKNALIYLAGQLEPDDSLAIVAFNDGMRVVLNPTSGENQMDIITAINSLEPAGSTNAEAGLYKGFELAWQAFKPEGINRILLCSDGVANSGMTEPSQLLATFQQYLDAGVQLSTYGVGMGNYNDILLEQLADKGDGNYAYFDSADEAQRLFGEQLTGSLQTIGREAKIQVNFDPNVVKRYRLIGYENRAVADSDFRNDSVDGGEVGAGHSVTALYEIKRHPDAQGPIAQVNIRYISMDTNAPVEESLNISTAQIHSSFDRASARMHLATSVAEYAELLRHSRWNNGTDILDVLDLAEEAALDLPNNQSAVEFVTLLRRAEQMHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWT7</accession>
    <name>A9AWT7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0690"/>
    <dbReference type="EnsemblBacteria" id="ABX03338">
        <property type="protein sequence ID" value="ABX03338"/>
        <property type="gene ID" value="Haur_0690"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0690"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150623_0_0_0"/>
    <dbReference type="OMA" id="HRCADAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-702-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="241" mass="27218" checksum="4DFE84F01341AE87" modified="2008-01-15" version="1">MSIETLFAHARAAISTGRKEEGRSLLISIIHENPDFAPAWLWLSGVLEEPEKRRDCLQRVLELEPTNEAALMGLEFLRLQVVVDQTPPAPPVEKSVAVVKRLGEYLVEQKFIKQIQLDAALSEQAQEARYGRIVPLGDILLRRRWLTTQALGKVLEVQKMARAQGGHASTINRLGEHLIEQGLITRTQLNQVIARQADLKVRGQNFQVGELLVLSGMLSRDQLQQAINEQQHTFMNELPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY0</accession>
    <name>A9AWY0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0733"/>
    <dbReference type="EnsemblBacteria" id="ABX03381">
        <property type="protein sequence ID" value="ABX03381"/>
        <property type="gene ID" value="Haur_0733"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0733"/>
    <dbReference type="eggNOG" id="COG0208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760153_0_0_0"/>
    <dbReference type="OMA" id="HYNFFLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-745-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="39234" checksum="63B5A4724F3B512E" modified="2008-01-15" version="1">MLHEQQTPVTPLVINGPWTREARERAIAEEVKLAYIEYFRKAVKTRNWLPWDDLPLREMEQYGHMLSEDTVTLVESFLGVEDYVGDYVEDTINIVHGKRERRNIQLQWGAEESKHAEAWELVLLHSGRRTKEQLETYRDQVAEHRWTMYENHPGFDTPLGVAAYAMVQERATYFNYEELRKRIRSEYGLPEQTTEEERKRGKQIGAAAAFKIVGVDEIAHHGMFLRVIDIYKRYLPYETLDMVFRVLNGFNMPALHILPNAEELKASLERTKLYTPLKHGRFVANPVLDAMGFNNKRALERAVQQAKLLPTGLGPEHVAIGRDGEFVISMQPDAEIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX79</accession>
    <name>A9AX79_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2247"/>
    <dbReference type="EnsemblBacteria" id="ABX04887">
        <property type="protein sequence ID" value="ABX04887"/>
        <property type="gene ID" value="Haur_2247"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2247"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_0_3_0"/>
    <dbReference type="OMA" id="GMGWFPD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2275-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732208" evidence="1">
        <location>
            <begin position="26"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="86"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="535" mass="58292" checksum="5343C9CC04E3A2D4" modified="2008-01-15" version="1">MDKRLSILGLLLLVLVGCDLGSNQATPAPASTPVAQSQAGGGGNFILTLGDDPATIDPALVGDTTSGFIARLMFSGLVTLNNELEAVPDLAETIDVSADGTVYTFKLRSNARFADGTPITAEDVRWSLERATDPSLGSIVSPTYLDDVAGVLEKVTGQANSLSGVKVVDDQTIAITLRQPSSLFLLKLTHPPAFVLDRRTVEDNSDWLEKPNGSGPFMLDLWNHRRRMELVPNPYYYGTAPKLDRITYLIGAEGSNPLGLYEQGEIDVTGIGSYDLDRINDEADPLHAELRITPQLQLSYIGLNVNQPPFDDPKVREAFYLLIDRVKLADVSYNGSVVAARGILPPGMPGAEPERLPEPNADIARAKQLISESSYGSVEKFPPIIGYSSGSGVGLLAQIAKDELGVTIEIRGQDQFGDYLAALERDNYHLYDLSWIADYPDPQNFLEVLFGSKGQYNRTNYSNAKFDQLIEQAKAEADAEKRGALYRQAEEQLLSDFVVIPLVHTVDYSLVKSYVDGYMITALGELDLTGVSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC4</accession>
    <name>A9AXC4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4212"/>
    <dbReference type="EnsemblBacteria" id="ABX06844">
        <property type="protein sequence ID" value="ABX06844"/>
        <property type="gene ID" value="Haur_4212"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4212"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_474658_0_0_0"/>
    <dbReference type="OMA" id="THPQRNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="288"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="548" mass="59387" checksum="ED5A955242909DF9" modified="2008-01-15" version="1">MSEPTQPMTGGTQPLNPVNQPEEHEPFAIGTVLKDIYRVTALLTDTPTLRVYRVALLEPWDHCARCGAALQASDQFCEECGAQVEEQTALLQETPAAQPIGAALLDDLPDDPARAALPTVREVFVGEDSRFAVLPDGTSLVRFDTLLSEPNTFVDQTDAVDIGIQVARALAYLHRHGLALGQLTLADLALTNKREIKLADAGAIRRSLGKEDQLDDVEHLGLVLEKMAGIQRQTRRLDDSNNPSPLDSAFATILSDLRAKRITDASILAQTLETLLAEQATPISLRVRTGYATDVGMIRDHNEDSVLTWDLRLNWDAKPVNVGLYVVADGMGGHEGGEVASGLAITTTAQTLVPTLLDPQLHAGPVSSKHLAELVKQAAFQANQAVYEESVRRKNDMGTTLTMAVVIGDRAIVGNVGDSRTYLYRDGKLQRISKDHSLVQRLIDIGQLDPDDIYTHPQRNAILKSLGDSGDPGTDTFEVQLQPNDALFLCSDGMWEMVRDPKMAALFAEHANPADLCDALIEAGNAGGGEDNISVVVVRFDALPIVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH2</accession>
    <name>A9AXH2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III, delta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4260"/>
    <dbReference type="EnsemblBacteria" id="ABX06892">
        <property type="protein sequence ID" value="ABX06892"/>
        <property type="gene ID" value="Haur_4260"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4260"/>
    <dbReference type="eggNOG" id="COG1466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044694_2_2_0"/>
    <dbReference type="OMA" id="EEPYYID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4307-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="3"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="35463" checksum="B46E43C25C2DCD93" modified="2008-01-15" version="1">MLYLFFGPDDYTRQATINVLKAAFPPDAAAFNVVVLHGKSIKLNEVRTACEAYPVFHDRRLVIVHDLLKHAKSAEMRDGLKSLVQRLPSTTDLVLNESDAPDSRLSVVKDIQALVKTKQAEQREFNLREGNALIAWMQQEAQSNGVQLRPDAAQHLANYVGSDGWMLHNEIAKLAAYVGQNGTISMREVDLLVADETETNLFNFIDALSTRRGAAAVQGLNGLLADDAAPLYILTMIARQARLMLAAQSAGRVAPDELAKLLGQKPFVARKAAEQARNFSPTELRMLHERVVQIDHGIKTGKIDAEGALASLVGDFGFAPNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ4</accession>
    <name>A9AXJ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0760"/>
    <dbReference type="EnsemblBacteria" id="ABX03408">
        <property type="protein sequence ID" value="ABX03408"/>
        <property type="gene ID" value="Haur_0760"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0760"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051623_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-772-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="416" mass="44603" checksum="1E409AF2EFA14A92" modified="2008-01-15" version="1">MGVLQRSTFSIAHLPLLQRLKQALGFWLVASMLLVNLGNYGFAIVLGRGLGPQVYAEVNLIVTCFALATLLSSMFQIYAANASVRPNNHATLRRLRQIAWGIGAASAGVCTGLAAFWQSKFHTSPTPLLVLGLGLGSYYALGVERGIMQSQAAFGRLALNALLEMLIRLIGAMIVVSLSLGVTEASVALTSSLLGAWWFSRSKPTVTQVDGVSHQTPSLWPIGLCLAGQGLLLNSDIVLVTLWFSSQIAGQYAALALIGRIGLFVSSTVATLFFAKLLRADQSTIQQREAFWQSLGITTIIGIVFSLACWAMPDLIVQALFGSAYLPIVSVLWRYAAIASGYALVNLLVSYQLAQQRLAGVWLILGAGSMQIVALGLFHQTINHVLGVQAGIMLALLVLVGLSEWLSCQKNRAESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL8</accession>
    <name>A9AXL8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0784"/>
    <dbReference type="EnsemblBacteria" id="ABX03432">
        <property type="protein sequence ID" value="ABX03432"/>
        <property type="gene ID" value="Haur_0784"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0784"/>
    <dbReference type="HOGENOM" id="CLU_2382179_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-796-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="94" mass="10476" checksum="C9D97BED0D910473" modified="2008-01-15" version="1">MQSPDQQPRSLNRANLSPEERKLRRSIALAMLFSPTMCVLPLLAFVARQSSSSVVIWGIWLLITLALVSVIWRAASGLRKIAEQRAQNESSSNL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP4</accession>
    <name>DNLJ_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ligA</name>
        <name type="ordered locus">Haur_0810</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide.</text>
            <dbReference type="EC" id="6.5.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXP4"/>
    <dbReference type="SMR" id="A9AXP4"/>
    <dbReference type="STRING" id="316274.Haur_0810"/>
    <dbReference type="EnsemblBacteria" id="ABX03458">
        <property type="protein sequence ID" value="ABX03458"/>
        <property type="gene ID" value="Haur_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0810"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007764_2_1_0"/>
    <dbReference type="OMA" id="HDVEHEI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018239">
        <property type="entry name" value="DNA_ligase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000380399" description="DNA ligase">
        <location>
            <begin position="1"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="594"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="35"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <sequence length="673" mass="73337" checksum="4EF16B7ADE0579A0" modified="2008-01-15" version="1">MAVSEQTVARAASLRDELNLYNHHYYTLDAPLVSDAQYDSLLNELRAIEAEYPELRTPDSPTQRVGSAPLSKFPKVQHPVPMLSLGNAFNADDLAAWRRRAEQIIGTQPMSYTVEPKIDGLAVALTYINGVFSVGATRGNGEIGEDITANLRTIRDVPLRLQPIDGQALPERIEVRGEVYLPIESFNQLNERQAHAGEKVFANPRNAAAGSLRQLDSTITASRPLRFFAYAVGPFSGVELKSQAQTLDTLRTYGFSVNPDTRLFADFEAVIEYCHEWMSRRESLSYEVDGVVVKINDFAMQRELGVVGRDPRWAIAYKFPAREETTTLLNIVINVGRTGKLIPNAVLEPVSLGGTTVQHASLHNADYIISRDIRIGDRVVVKRAGDVIPYVIGPIVEARTGDERVWPAPTHCPTCGQPVEQIGDEVDIYCVNNTCPARLIRSIEHWVSRGAMDIVGMGERQASQFVEMGLIKSIPDIYRLTVDSFGGREGYGERRVANLLNAIEESKRRPLDRVITALGINGVGTVAAADLARYFRSLPALAQATIEQLTAIEGIGGSTAQSVVDFFNTPANQQLIAELLALGLKAEPSEVAELQSDRLAGKSFVITGTLPGISREAAQALIEAHGGKVGGSVSKKTDYLLAGEAAGSKLTKAQSLGVKVLSMDELHALLVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR1</accession>
    <name>A9AXR1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX03475">
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        <property type="gene ID" value="Haur_0827"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-841-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="LodA_C"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="12"/>
            <end position="232"/>
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        <location>
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            <end position="492"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="645"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="629"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="645" mass="70929" checksum="AB849FD0D68AC73B" modified="2008-01-15" version="1">MAGAEIVSVAIYPPVGFARVGNSPNEFFYGPEVLGAPQVDPDLFRDPSGAIKRQAARFRVYGLNAAGEVICELNQTNPDLQEIVWTAQLANQKAAWYEFIQALDIPASADGKIVSKRRNADVTERDQLTIDGGTRSICGLNVNPQGQEAIYAFDQGTFFGKHVYLGELRTDEQGNLIVLGGRGHSASAHGKPLTTFADNDDWHDDTADGPIEAVVKLSDGRVLQATHAWVIVAPPDYAPGTNSIMTGYDLLFEVAMQLDPTLAPAKPRFSSEIYPLLSRFSQLQWVNAGFARSFGWGSPSDFNNPELIARLGDPSAASEPLRQAVLAQMRNPSNPYIDPEGLPLFYGDAITLNTKTTDPQEWQAILPSQYRWLEQWANGDFIADGLPVVRPWAQLDPAEQAYNLTRAALDATLGGPFHPGCEFTWPLRHTSMYAAPFRLKRRTSPEPDWGDTLDAATALAPDGMLYASDAGAITRWMAVPWQTDTSSCLSAYMGYAGTYLPTFWPARVPNDVLSQESYQIIMNPDATPEERAQAFAPTARRKWLRGMVYTESIPPGHIPTVPAITKFTNEWDTVGIIIAQTGPEHSASFPQTLWVETGRHVESEAPQLTRSLAAEPETDLVDSDLNWPQQRLKRGRKNAAEANND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS9</accession>
    <name>A9AXS9_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX04895.1"/>
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        <property type="gene ID" value="Haur_2255"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX04895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="378" mass="42667" checksum="DC25D58E59617402" modified="2008-01-15" version="1">MTANSKHQAWQIGLIIGFWPIVLFALFNDSAWLYAQSFNGQIISNIAAPLYFGLMLYHLRPDQRLIALVFVPFSALGEYVFSLLLELYSYKFEAIPIYVPFGHAILLSTGLLISELAWVKQREKQLRWSLLLGHVSLFIGAFLLFDDSLSLLFGLGFSLILLLYRAQLLHLIMGFLVLYIELLGTWLGCWRWDLNPLNGLLHTTNPPVGAFVCYVIADIIVIMSLRWLRWMRGYRRNPHAKGSAAYYQQKLALTQQIYAEQGGKSAISNDDGFGKGYALGTVGLRYVELNQDSAAITCFERTRQLAQSRNDQAIFHLAGWHLGQILLQQGQEHEAMTLLQAYVNYLQASNSTQAEHFAAQLAQAQPNTNDNSSSAVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY08</accession>
    <name>A9AY08_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
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        <name evidence="7" type="ordered locus">Haur_2334</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2334"/>
    <dbReference type="EnsemblBacteria" id="ABX04974">
        <property type="protein sequence ID" value="ABX04974"/>
        <property type="gene ID" value="Haur_2334"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2334"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_0"/>
    <dbReference type="OMA" id="NLAWCHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2362-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Mopterin_OxRdtase"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="716" mass="77226" checksum="593A0D53D83B386C" modified="2008-01-15" version="1">MSNVVRSQCPYCGVGCGIELTVNDGKVVRVNGDSAHPANQGKLCIKGATIEQMLTPTTRLIHAQIRSDRNAALHSVGLDQALDHAAQRLNAIRQQHGNEAIGFYLSGQLTNETSYLVTKLCKGLMGTNTMDANSRLCMASAVAAYTRTLGTDGPPCSYSDIEQADCFLIVGSNTAECHPIVYRRIEQQVRKHGAKLIVVDPRRTQTSRYASLHLAAAPGSDTALLNGLLHILIRDGAVDYEFIAQHTTGWSEIAEAVAGWTPAQTALATGLTVEEIETAGAMLVASQRTLSMWSMGVNQSRNGVAKATAIINMHLATGRIGKPGCGPFSLTGQPNAMGGREVGYLAHQLPGYRRVDVAEHRSAIEQAWGIPIGSISATPGPDAQTMFSQLAEGKLKAIWIIGTNPLHSMPNNSTIRAALEKAELVIVQDVYHTSSCLAYADIALPAAQWAESIGTFTASDRHITLLNPAYPAPGDAMPDWWLVQAVAQRMGFELNFANAEAIWDEYRGLTAGRYPLDVSGVSYERLRNGPLQWPCPAEDHAGTVRLYSDGRFATANGRANFQVTIPVEPAEVPSYEFPFWLTTGRVLEQWHTRTRTANVAKLNQRHNGSFIEIHPDDANTLGVSAGEKIAVIGRRGSCTSIVQINPEIMPGCLFMPIHWEDGNPNVLSINAADPMSKQPELKACAVQLRPIVEGINIKFGEAASVPAMAAGKRSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY63</accession>
    <name>A9AY63_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4313"/>
    <dbReference type="EnsemblBacteria" id="ABX06945">
        <property type="protein sequence ID" value="ABX06945"/>
        <property type="gene ID" value="Haur_4313"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4313"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_20_2_0"/>
    <dbReference type="OMA" id="GEQPAAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4365-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="17052" checksum="364775273668000E" modified="2008-01-15" version="1">MTKIHPPSHRVAAFAIIFSSNGAVLLSRRAESGWWNLPGGGVEAHESVSEGIIREVREETGLEVAVTRLVGVYSKPQKHEVVLTFECHVLGGELQITEESSEHQWFAPEQLPTEHFLPKHRERVLDALSNQPAAILRDQRSPSVGDHQSNHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY65</accession>
    <name>A9AY65_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mevalonate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4315"/>
    <dbReference type="EnsemblBacteria" id="ABX06947">
        <property type="protein sequence ID" value="ABX06947"/>
        <property type="gene ID" value="Haur_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4315"/>
    <dbReference type="eggNOG" id="COG1577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_0_0_0"/>
    <dbReference type="OMA" id="NTVCTYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4367-MON"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="PTHR43290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="5">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="6">
        <location>
            <begin position="221"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="33052" checksum="61E14E10E7437BE5" modified="2008-01-15" version="1">MNSAPGKLILAGEHAVVYGQPALAMPIAALRASVAVEPAPRGAGMTVHAPDLGLVWRLRATAPLSDLAQRTLDYLQLPEPDLRLTISSSIPIASGMGSGAAVGAALVRALAEQAGQQLSAQVISDLVYQSEKAFHGTPSGIDNTVVAYEQPILFQRQTQGEPLIAPLAVGNQWHFVVADSGIASETKAVVGDLRQRWLADPELYNRQFVAVGNLVRQIQTALAGNDAELFGQLLSQNHQLLQTLGVSAEKLDYLVQTALAAGAWGAKMSGAGWGGIMLALVPAERASYIQQQLRAAGAVQTWQTSLLPTDSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF7</accession>
    <name>A9AYF7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosidase PH1107-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0891"/>
    <dbReference type="EnsemblBacteria" id="ABX03539">
        <property type="protein sequence ID" value="ABX03539"/>
        <property type="gene ID" value="Haur_0891"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0891"/>
    <dbReference type="eggNOG" id="COG2152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046648_0_0_0"/>
    <dbReference type="OMA" id="KAVQMNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-905-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016202">
        <property type="entry name" value="PH1107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="332" mass="37161" checksum="5CE07C68E7303D5A" modified="2008-01-15" version="1">MEAATLQSTTILGSALPSIPWEERPVGNSDVVWRYSGNPVIPRDAIPTSNSIFNSAVVPFKDGFAGVFRCDDKRRVMNIHRGFSKDAVNWEIDPKPLEFSGDPEVTAFEYRYDPRVCWIEDRYYVTWCNGYHGPTIGVAYTYDFETFHQLENAFLPFNRNGVLFPRRINGKYAMVSRPSDNGHTPFGDIYYSESPDMEHWGKHRFVMGTKGGWQSTKIGAGPTPIETTEGWLLFYHGVLTSCNGFVYSFGAALLDLEQPWKVIYRTAPYLLAPQTLYECVGDVPNVAFPCAALTDAATGRIAIYYGCADTVTGIAFAQVDEVLSFLKANSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF8</accession>
    <name>A9AYF8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0892"/>
    <dbReference type="EnsemblBacteria" id="ABX03540">
        <property type="protein sequence ID" value="ABX03540"/>
        <property type="gene ID" value="Haur_0892"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0892"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_0"/>
    <dbReference type="OMA" id="VSWTILN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-906-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38369" checksum="29F5EC510DD6CCE4" modified="2008-01-15" version="1">MTQRITMEDIARQSGVSLATVSLVLRDKPGINDETRRRVLDIARDLGYRKRLNHEKLVSQSLHNAGVIVKASIGDDSPLTNPFYAPIVAGIEAACRKMHINLMYATVPVDMDNHPQEMPRLLSEDHLDGVLLVGAFADATITKLLQREGIPAVLVDGYSHEHVYDSVVSDNFRAAYEAVSYLISYGHRHIGLIGTTKEAYPSIAERRKGYIQALTDHGIHDQYFGDCLLTMHEGSDTSSILLQRHPQITALFCANDMMAIGATQAARALHRQIPQDLSIIGFDNIDLAQHVAPALTTMHVDKVSMGRFAVQLLANRAEYPDQAPATVSLRPRLLERQSVQRLQPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ5</accession>
    <name>A9AYJ5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Homoserine O-acetyltransferase</fullName>
            <shortName evidence="2">HAT</shortName>
            <ecNumber evidence="2">2.3.1.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Homoserine transacetylase</fullName>
            <shortName evidence="2">HTA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">metXA</name>
        <name evidence="5" type="ordered locus">Haur_0929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13701"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="EC" id="2.3.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.31" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0929"/>
    <dbReference type="EnsemblBacteria" id="ABX03577">
        <property type="protein sequence ID" value="ABX03577"/>
        <property type="gene ID" value="Haur_0929"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0929"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_1_2_0"/>
    <dbReference type="OMA" id="TRFCVVS"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="64"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2 3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="390" mass="42302" checksum="DA2BA1C7C3568012" modified="2008-01-15" version="1">MTDTVTLGDVPTVTQPAWGRSVGFVTPQVQIFTEPFRTASGALIPAPWQLSYETYGKLNADRSNVILLCHALSGDAHAAGRYSVHDSKAGWCEPFIGPGRAFDTDRYFVICSNILGGCGGSTGPSSLHPHTGTHWGSRFPVLTIGDMVAAQVRLLDALGIERLLAVAGGSLGGMQALEWAASWGDRVRGVIALATTARSSAMAMALSAAGRQAIVSDPDWRGGDYYGTAGPVNGLATARRIGHISYLSAEALEEKFDRRWQHEASPQWSHQPEFAVESYLDYQGRAFVQRFDANSYLVISRAMDYFDLSQRAGGLTTAFANTQARFFVATWSSDWLYPERDGELIQQAAQVAGRTVVHYPFHSTKGHDAFLLEDAQLTPPLIDWLASLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ55</accession>
    <name>A9AZ55_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0953"/>
    <dbReference type="EnsemblBacteria" id="ABX03601">
        <property type="protein sequence ID" value="ABX03601"/>
        <property type="gene ID" value="Haur_0953"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0953"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_9_0"/>
    <dbReference type="OMA" id="RLWILND"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-967-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="16626" checksum="7CAC4072F78C64DC" modified="2008-01-15" version="1">MQIIQASLDELERLVPLFDGYRQFYRQTSDLAAARAFLHQRLSNNESIIFLAQTPEAGLGFCQLYPSFSSVSMQRLWILNDLFVAEHARGQGVASGLLNVARDWAVSTNSKGLVLETEASNTSAQRLYEQHGWQRDLAEYYYFLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ90</accession>
    <name>A9AZ90_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0988"/>
    <dbReference type="EnsemblBacteria" id="ABX03636">
        <property type="protein sequence ID" value="ABX03636"/>
        <property type="gene ID" value="Haur_0988"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0988"/>
    <dbReference type="HOGENOM" id="CLU_2699673_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1004-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8173" checksum="FC7814925348BE3B" modified="2008-01-15" version="1">MLTIEFIQQHLRQAIAQAIEAKNPAELAHLQQMAGLLMKPAHLHNDSETEYALRLLAAKAANARESLLKKEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ91</accession>
    <name>A9AZ91_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0989"/>
    <dbReference type="EnsemblBacteria" id="ABX03637">
        <property type="protein sequence ID" value="ABX03637"/>
        <property type="gene ID" value="Haur_0989"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0989"/>
    <dbReference type="HOGENOM" id="CLU_2861639_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1005-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="64" mass="7024" checksum="BFEED2B4DDE4B4A7" modified="2008-01-15" version="1">MALSIDAIYEYAEALIARKTLDGGQIELRQMQRLCEFLADLAQQADDSANAQRFAHLAQAVKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD6</accession>
    <name>A9AZD6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2440"/>
    <dbReference type="EnsemblBacteria" id="ABX05080">
        <property type="protein sequence ID" value="ABX05080"/>
        <property type="gene ID" value="Haur_2440"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2440"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1249209_0_0_0"/>
    <dbReference type="OMA" id="WAPKDSM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2468-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="24948" checksum="8318C86B2EFB9EEC" modified="2008-01-15" version="1">MNEPFPTAQFWHPLACLALVAAIGHSLLWLDAWWQQLLALSLIYGWLWWHIRAAIWPHVGLMLLSCGLLGLSLGLSGTWSLALQASLRLACLGIVGLCLFMLVEPSALIDSLYQLGLPLNLVRLLEGSLSTLPAMLRIVQQTRASLATRGMRTDRWYLLWNGRWLVLPILAQALQHADDLAEALHTRGLSDQRPTILQAYPWRWQDWSLLVLSGLSLLIWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK2</accession>
    <name>A9AZK2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2508"/>
    <dbReference type="EnsemblBacteria" id="ABX05146">
        <property type="protein sequence ID" value="ABX05146"/>
        <property type="gene ID" value="Haur_2508"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2508"/>
    <dbReference type="HOGENOM" id="CLU_569582_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2536-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="479" mass="51914" checksum="AFD3C289106205CB" modified="2008-01-15" version="1">MARQTWIRRSGIVASLVLALWGCGEYIAPATKLTINPNADSGAYYPAIYVDNNDLRHYAWAECQAGNGCDLIYTRMRGSSELLRQTITITNSTASLVYPSLTADNTDTIHLAYLSNQPVPARGDSTYRYYAVSISPDGATISQPVNLQGESINSSLISPIAVRNNDGSHVGVLYTMLDSNQQSLVYRQIAPSLSQPVVIETVASNIILTQPRISIDANNTIHVVYGKRSPISPTRNLGGDPTLDEIRYAHGTLIGITARTVDSYTSASASIPFVYDLTLTDKAYVTYIKHPSATLRGIPTDSLRSHNATDNLTTDLVLPSILEPWNIGEISTVNSGSGRPTVYFAGTNNTFTDAFAFDIWQYDAQASAAMNLSNTANRYENNLASSHFHALDLVAWQADSFDSNGCTTQIVSYRSDIEQTNVAEQFLNPLGCTPSVLQISAGDKVAAGVWISVARNNATLNVPATAFNSYGTFLPIAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR6</accession>
    <name>A9AZR6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="2">RPPK</shortName>
            <ecNumber evidence="2">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="2">P-Rib-PP synthase</shortName>
            <shortName evidence="2">PRPP synthase</shortName>
            <shortName evidence="2">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prs</name>
        <name evidence="4" type="ordered locus">Haur_4488</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4488"/>
    <dbReference type="EnsemblBacteria" id="ABX07120">
        <property type="protein sequence ID" value="ABX07120"/>
        <property type="gene ID" value="Haur_4488"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4488"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_1_0_0"/>
    <dbReference type="OMA" id="FGWARQD"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="3">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="38"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="312" mass="33240" checksum="4E8B3B8F5B99CD97" modified="2008-01-15" version="1">MDGRLQIFTGNANIPLARSIASHLNLNLGRAIVGVFKNGETRVQLEENVRGSDVFIVQSLTTPVDHHLMELLLMIDALRRASAQRVTAVIPYYGYAKQEKKTTGREPISAKLVANLIATAGADRVLTMDLHAPAIEGFFDIPVDHLQAGPLIADHFRSRNMKNVVVVSPDAGGVGRANKFRERIGASLAIIAKQRPAPDVSEVVEMVGDVAGKHAVIFDDMISTGGTLAEAAKTLKERGAISVVACATHGIFAGNAVELLGDSVMEEVLVTDTIPLPAEASAARIAQISVASLFAEAIIRIHKDLSLSALFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR9</accession>
    <name>A9AZR9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4491"/>
    <dbReference type="EnsemblBacteria" id="ABX07123">
        <property type="protein sequence ID" value="ABX07123"/>
        <property type="gene ID" value="Haur_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4491"/>
    <dbReference type="HOGENOM" id="CLU_048553_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4546-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="482" mass="53240" checksum="072163FC8D957CCC" modified="2008-01-15" version="1">MVEAHLFGFGGALWLALFIATRTPQRSLLFWASIISLFGLMGFFGSGVLGGEGLNLEQLVSLERGFWWSSVLPITTWLIVCSLIHQTLQPSIATIVKPERWVVGVIGLILIGLGSSSNWLMNYAEPVLLASGSQIIGTGPAYPIYSAYVMGCVSVALWHLVASWRIAETGMARRSLASLVLGALGFLIGTSSLLARLISTGTWPLFYGYMPIFAGLLITGFGLVRFGLLLQGQNVLRDLIYSFCEISILALIYLISVNILDLLRPSQLALLLACVIISHTGLDRGRRWLDRLFFSRAEQEARSQSREFALALASTPTPTPAPVIVDAKPDKAWNDAVRRAISGLKNPVQLAQNPLLSSALVSHSVQSKALEDNRLNRSAIAREILLQAIEQLRPDASQALGSGDAWRWYNVLYLPYVREINRKTAIDWLRRGLSDPLIDASVLSWLADIDEDTFYKWQRRASDLIAAQLWEQQLKLVQPVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS8</accession>
    <name>A9AZS8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1324</name>
        <name evidence="3" type="ordered locus">Haur_2730</name>
        <name evidence="4" type="ordered locus">Haur_4500</name>
        <name evidence="5" type="ordered locus">Haur_5171</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 6" key="3">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1324"/>
    <dbReference type="EnsemblBacteria" id="ABX03969">
        <property type="protein sequence ID" value="ABX03969"/>
        <property type="gene ID" value="Haur_1324"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05368">
        <property type="protein sequence ID" value="ABX05368"/>
        <property type="gene ID" value="Haur_2730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07132">
        <property type="protein sequence ID" value="ABX07132"/>
        <property type="gene ID" value="Haur_4500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07799">
        <property type="protein sequence ID" value="ABX07799"/>
        <property type="gene ID" value="Haur_5171"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1324"/>
    <dbReference type="KEGG" id="hau:Haur_2730"/>
    <dbReference type="KEGG" id="hau:Haur_4500"/>
    <dbReference type="KEGG" id="hau:Haur_5171"/>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042765_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1345-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="113"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="442" mass="48254" checksum="5C79D06C0E1FFE6A" modified="2008-01-15" version="1">MSIIPHVSDAMQTVLTTTTETVAATLGYVKRADRATFTPSTLVQTLVYGWLANPTASLGQLAQMAARVGATVSPQAIDRRFTLATVDLLHHVLLASMEYAISADPVAVSILQRFTSVRIHDSTTIGLPDALATTYRGCGNASARGTAGLKCGVQLDLLTGTLCGIDLTDGRASDQVLSVQRAPLPAGSLRLADLGFYNIRIFRELAAAEVYWLSRVQSHSRIRLPGQKEQSILEVVTGLGDADHWEGTVLVGSKERLAARLLVQRVPDAVAAQRRQRVQDEAHDKCRPVSNAAMDLAAWTVVITNAPEDKLGLTEAMVLLKMRWQIELLFKLWKSHGHVDEWRTKKPARILCEIYAKLLGLVFQQWILVASAWDTAERSLFKAAQIVMAYATDLASSRGCREQLETVLTTLASIIGRLARVQKRQKRPSTAQRLLALTAGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZT3</accession>
    <name>A9AZT3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PT repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4505"/>
    <dbReference type="EnsemblBacteria" id="ABX07137">
        <property type="protein sequence ID" value="ABX07137"/>
        <property type="gene ID" value="Haur_4505"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4505"/>
    <dbReference type="eggNOG" id="COG5624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_599608_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4560-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734449" evidence="2">
        <location>
            <begin position="30"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="453" mass="46634" checksum="B2BB6311DDF155B3" modified="2008-01-15" version="1">MTPTLRRWTTRVVLLATMLMAGGPSASFANVSKGVESASVETVVEPTAEPTAEPTAELTAEPTAEPTGTAAPTAAPTGTAAPTAAPVCDPKADLSGWFSSNTVGKIWNKSSTCSYDVGMASYQKFDEIIDHQLIYSWAIGRVGPKTTVSLSVSVPDCATQIDVFYGPVLHSLDGQRYGERLLSSRHLGGTSYCGVTTPTNTPEPTAEPTVAPTNTPEPTAYPTPTAEPTVAPTNTPEPTAEPTVAPTNTPEPTVAPTVAPTNTPEPTVAPTNTPEPTAYPTPTAVPTATKTPVPTATKTPAPTATSTPAPTATKTPVPTATKTPAPTATSTPTGKDCTYTQGYWKNHPSAWPVTSLSIGGVVYSQSQLMAIFNTSPRGDATYILAHQLIAAKLNVAQGANGSTVNATIAAADAWLQQYPLGSKPSGSASNTGTSYATQLDNFNNGVIGPGHCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZX7</accession>
    <name>A9AZX7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1036"/>
    <dbReference type="EnsemblBacteria" id="ABX03684">
        <property type="protein sequence ID" value="ABX03684"/>
        <property type="gene ID" value="Haur_1036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1036"/>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_0_4_0"/>
    <dbReference type="OMA" id="NKGGGAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1053-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="36543" checksum="403928920D7E692F" modified="2008-01-15" version="1">MIDLRSDTVTKPSLAMREAMHHAEVGDDVFGDDPTVNQLQRYAADLVGKEAAIFVPSGTMGNLAAILAHAGRGQELLLGDESHIYHYEAGGASALGGLVFHPIPTNAQGELDLAALNAAVRPAYDAHAAQAGLVCLENSHNRCGGTVLSLEYLAQVQQWASSQNLPVHMDGARVFNAAVALGVPASTITKHVDSVQFCLSKGLGAPIGSIVAGSGEFIKKVHRWRKMLGGGMRQVGVVAAAGMIALNEGRERLIDDHVNAKMLAEALSQLPQIELDLASVQTNIIVFGLRDSTFSPEQLVERLRQAGVLIVPFKGRLRAVTHVDVNREQCTEASSIIAEVLQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B074</accession>
    <name>A9B074_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-glucosidase</fullName>
            <ecNumber evidence="6">3.2.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2545"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05183">
        <property type="protein sequence ID" value="ABX05183"/>
        <property type="gene ID" value="Haur_2545"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2545"/>
    <dbReference type="eggNOG" id="COG1501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_7_2_0"/>
    <dbReference type="OMA" id="QGVDCFK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2573-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032450">
        <property type="term" value="F:maltose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4968" evidence="4">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Gal_mutarotas_2" evidence="3">
        <location>
            <begin position="126"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="5">
        <location>
            <begin position="678"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="785" mass="88059" checksum="5A71CF163E2B0268" modified="2008-01-15" version="1">MEHSSMFTLDQRDARSCLFKRANQQIRISICSEQLIRVCISNDAPLARRSWAVNRADDAWEALAWSVSENSDSTRIETTKLQVNVAHADGRITFNNLEQQPFFSDVTPASYNADGWVVRKQIYNSEHFYGFGERTGWLEKTGQHFLNWTLDPEPHHSPRIDNMYATMPVFMGLQPNLCYGVFFNTSFRSSIDVGAADAALLSLKTQGPDLDYYVVLGTTPAEITATWRELLGAMPLPAYWALGYHQSRWGYDSSMTMQAIADELRARNIPCDAIHFDIDYMDGYRVFTWHPERFAQPAQLLQNLARDGFNVVTIIDPGVKTDPNYAVFAEGIANDYFIKRADGTLFSGYVWPDDSAFADFTRADVREWWGNLHKKLIDAGVRGIWDDMNEPTVFDRPFSEGGGNGGTIDLNAPQGSADERTTHAEVHNLYGLLMARSTYEGLRQLRPNERPFVLTRSGFAGLSRWATLWTGDNSALWEHLEMMLPQIANLGLSGIPFVGVDIGGFFGNASPELWARWVQVGAFLPFCRGHSCSGTRPAEPWAFGERTEAIARAYLSLRYRLLPYLYTLFYQASTTGAPIIRPLVYEFAADPTTHALHDQVLCGSQLMLAPIVRPGTEYRSVYLPAGEWYDWWTGERIKGSQHILVHAPLERLPLYVRGGAILTLGPVLNYTSEAPLDPLTLDVYPSGTSEWTLYEDDGISFDYEQGQAATTTFSCVETEQTITLMIAARQGSWQPALRTIVVNLHSLPPKAVLFDTNAIEWVYAEGATTVSFADDGLAHTLEVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C3</accession>
    <name>A9B0C3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2594"/>
    <dbReference type="EnsemblBacteria" id="ABX05232">
        <property type="protein sequence ID" value="ABX05232"/>
        <property type="gene ID" value="Haur_2594"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2594"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040537_1_1_0"/>
    <dbReference type="OMA" id="YFYMASF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2622-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="42091" checksum="B7170BD3AC707D83" modified="2008-01-15" version="1">MATRTSGQAVALTGLSVMVMMTFSHAMNDMWTSLLAPLLPSIRDTYQVSIGQTGILVAILSFAGSMLQPLLGAVGDYIDRRWLAAFGPVLTAIGLTLIGYVPNFFMLGALIMLGGLGSAIFHPAGAAYIAMGANPQQRGLFVSIFSAGGTVGMAFGPLIAAQFDLVSLPYLLPVGIAVGVLTFLMIPSAKQNRSQPKTLRDYISVFQGPLRWLWFMSVLRSLSSVSYSSLLGFMLRDRFDQAMADAHVGPTLAVFNIASAVGGIIGGRISDRIGRTVVLRSSILSTIPLFIGLVLSSPLNWWYYPLTALVGAMVMANIPVSIVTAQEYAPQHIATASAMMMGFAWGTSGVLYPIIGSLADWTSPTWAMIAAIGLLLPAFFITVRLPEPERTTTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C7</accession>
    <name>A9B0C7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2598"/>
    <dbReference type="EnsemblBacteria" id="ABX05236">
        <property type="protein sequence ID" value="ABX05236"/>
        <property type="gene ID" value="Haur_2598"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2598"/>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110659_2_0_0"/>
    <dbReference type="OMA" id="QIGGNWC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2626-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="19320" checksum="506349647B13A0FC" modified="2008-01-15" version="1">MADSLFDPERDPFADMRNALETAQRERKNILVELGGDWCVWCHRLEAFINAHPQLRYLRDIHYVKVKVLVGDEQQKNKTFLEHLPGFDGVPHIFIYNSRGQLLCSQDTSPLEEGESYNFGRVRDFLSRWSEWRLSPYDALATDELKRLVELHYFGEYANQITPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0M8</accession>
    <name>A9B0M8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4615"/>
    <dbReference type="EnsemblBacteria" id="ABX07246">
        <property type="protein sequence ID" value="ABX07246"/>
        <property type="gene ID" value="Haur_4615"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4615"/>
    <dbReference type="eggNOG" id="COG2064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056917_4_0_0"/>
    <dbReference type="OMA" id="SIKRAWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4672-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="164"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="301" mass="33458" checksum="911A9748E36F127C" modified="2008-01-15" version="1">MPLLIGLVVLVIVFGVGFMVLNQRRQTDTVSSRLAQFTERSMNLEDLELQLPFMQRVVTPMLNNVFVKLGQSGKGNDKLRNNLMLAGNPGNLTPTMFTGMRIFMALALFGVIFLICMLAKVQTLSAIQWSGVGGALGFLLPAMWLGRQIKKRQKLILKALPDALDLLSISVTAGLGFDAALQRVAEKWDNELCREFRRALSDIRLGTQRHEAFRSMTVRTGVEDLTSFVSAVIQADQLGVSMGKMLKIQSDQLRLRRRQRAEEEAQKAPIKMLFPLVFLIFPSMFVVILGPAIPRLLGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S8</accession>
    <name>A9B0S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1150"/>
    <dbReference type="EnsemblBacteria" id="ABX03798">
        <property type="protein sequence ID" value="ABX03798"/>
        <property type="gene ID" value="Haur_1150"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1150"/>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_4_0"/>
    <dbReference type="OMA" id="TEWITYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1172-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734469" evidence="1">
        <location>
            <begin position="24"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="46849" checksum="FE039C8ED48DB5BD" modified="2008-01-15" version="1">MQRPWIRSFTLLIGLILAACGEATTPTTPPTNPTTATGASSAASGTVTLWFHSGQGAERDALNATLQAFAAKNSAIKVEAIELPEGAYNDQVNAAALAGELPCLLDFDGPFVYNYAWSGYLQPLDSLIAADVKADFLPSIIEQGTYNGKLYSLGQFDSGLGFYANKELLEKAGVRIPTLAQPWTRAELDEALSELKANGLEYPLDLKMDYGRGEWFSYGFSPFLQSFGGDLIDRSTYQKASGSLNSAASVEAMKWFQGLFTNGYVNPKPAGSTDFAEGKAALSWVGHWAYPDYAKALGDKLLVLPAADLGKGAKTGMGSWNWGITSKCANPAAAAEVLSFIVSPEEVLRMSDANGAVPARTSAIAKSKLFGDGAPLNLYVQQLTNGVAMPRPITPAYPVITVAFAEAVDNIVAGADVQAELDKAAQKIDADIEDNQGYPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U8</accession>
    <name>A9B0U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding CenC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1170"/>
    <dbReference type="CAZy" id="CBM8">
        <property type="family name" value="Carbohydrate-Binding Module Family 8"/>
    </dbReference>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03818">
        <property type="protein sequence ID" value="ABX03818"/>
        <property type="gene ID" value="Haur_1170"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1170"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025052_0_0_0"/>
    <dbReference type="OMA" id="WWNVHNG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1192-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734470" evidence="2">
        <location>
            <begin position="26"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="693" mass="74378" checksum="C4F7BE3423CE5C00" modified="2008-01-15" version="1">MRRLVQLSLLMVLGVAWLGSTRAHTAIPNGTSIVFDEALATGWQNWSWSTAAAFDSTAQAHTGTKSTAITFEAWGGFSLHSPGLIPAEALTGISFWVYGGTGGAQFNAGVTTSDSGNIVAAVPVNAPAGQWTQVQLTMAQLGNPSAVSRINLQESTGTAQATFYIDDLILNIVDFAPPGTVNVTIDTDQTVLDFSARNALGTNYGMWGVEAAANSTFLARSGALGNMTIRLPGGSMSQDHGAINCELGTGNTIANAWPCNYEWAMTPTDFIEFLSATDRDAIWTINTNVTSGEAAALVAFFNGDVNDQRALGTDHKGVNWQTVGHWAQLRASHGNAAPVGIKYWDFGNETYGSCVQGWEVGWTCDGAEYINGLPAPNRHEGYLEVRAAMKAVDPTIMVGVTGLANPTEFNNWTTKVLTEGGDVIDYLAIHPYSFVDVPNNDALGRYLMLSRPQKQWPEVFASTRQAIADFADGRNIPIMIGEYNLSAGWPYDPQAMMTKALNMLFIADTTGQIIQGDVLAANHWLLNGNVQSNGTDYGLIGDVPTYTRSPQYYAFHLWQFFGNRLLEYTSDADAETQISMYAGSDGHTISLMAINKTGQATTTNVQLRAGGVVIPAISGSIDVAQAVSLDATTITYNGQTNVNDDFSNAQTVELTEVGETTTVTLPAYSITLLRFATDDGIHTLYNPLVLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B155</accession>
    <name>A9B155_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2695"/>
    <dbReference type="EnsemblBacteria" id="ABX05333">
        <property type="protein sequence ID" value="ABX05333"/>
        <property type="gene ID" value="Haur_2695"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2695"/>
    <dbReference type="eggNOG" id="COG4767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1862427_0_0_0"/>
    <dbReference type="OMA" id="KLATRWS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2726-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="14850" checksum="B4C5F74AEE4F06ED" modified="2008-01-15" version="1">MALLYTLAVFGLAWHNWTGSTTQPSLQLQIGATISAAFQQGGRAALINIIGNVAAFAPSGWLLAFWRPKLRLWLIGLIGLGLSCTVELGQYWLGYRVVDIDDVVLNSLGFSLAGSVARASQRLIQRCTREVDRGDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B173</accession>
    <name>A9B173_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2713"/>
    <dbReference type="EnsemblBacteria" id="ABX05351">
        <property type="protein sequence ID" value="ABX05351"/>
        <property type="gene ID" value="Haur_2713"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2713"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_1_2_0"/>
    <dbReference type="OMA" id="YNPGHVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2744-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="26"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="119"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="162" mass="18190" checksum="76195CCA9F6F7E35" modified="2008-01-15" version="1">MEIKWTPWRGQFVKGETPKDSRCVLCVKHEESNDAENHVLYRGQFSYVLMNLYPYNPGHLMIVPYAHTNDFANLSAETAAEIMHLTQRSATILSTVMNPHGYNLGMNLGRPAGAGIDEHLHMHIVPRWNGDTNFMPLIGGVKLIPEAMDDTYAALVGHFQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G2</accession>
    <name>A9B1G2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4718"/>
    <dbReference type="EnsemblBacteria" id="ABX07349">
        <property type="protein sequence ID" value="ABX07349"/>
        <property type="gene ID" value="Haur_4718"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4718"/>
    <dbReference type="HOGENOM" id="CLU_105789_3_1_0"/>
    <dbReference type="OMA" id="HDRNHLL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4776-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="19044" checksum="90BF41FE46CA51AF" modified="2008-01-15" version="1">MSNHDQLALVRQRHIHLMQLTLDTLGHVLSDVTQAQATTFRDGPDGWTVVEVLCHLRDYDQIFLERAIMMRDGDFPLLPIYDHEAMVIERNYNSNDLRTVYAALQESRPRFIAFFQALTPEQWEKAGTHPERGYFSLTDAAMQVGIHDVTHLEQITRILLQAKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I6</accession>
    <name>A9B1I6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4-phytase</fullName>
            <ecNumber evidence="4">3.1.3.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.26" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1223"/>
    <dbReference type="EnsemblBacteria" id="ABX03871">
        <property type="protein sequence ID" value="ABX03871"/>
        <property type="gene ID" value="Haur_1223"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1223"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_0_3_0"/>
    <dbReference type="OMA" id="RVFVNAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1245-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008707">
        <property type="term" value="F:4-phytase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731788" evidence="2">
        <location>
            <begin position="22"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="119"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="589" mass="63923" checksum="8F3D8D8877F7C5E7" modified="2008-01-15" version="1">MLKRRLTRLLALLVLTVPTLAACGAGDATPTTAPAAATATTAPATGAEATATTAPVAEATATTTEATAEPAATEGNVLRVHQVAYPDVFDPQKSSYSAEIVLLSQNYEGLTRLNDKLETVPGAAEKWESNAEGTVFTFTLRPDLKYSDGSALTSKNFAYAIERTCDPVTAGEYQSILFDITGCADFASAVVTDTAQYDAAKAALGVSTPDDKTIVISTVQAAPYLPTIAGLWVMYPAKAELIEKGGENWWKDASLQVGNGPFQFSRIAEDQQIDFVRNENYWNKAKLDGISMIYIDDSSVALEAYRQGQLDIFQPDPSQIPAVQSDADLGPLYISYPGANTTGLQFNTTTEPFNDPKVREAFAYAIDRETFCEVIRNGDCLPTLTWIPQGIPGYDATEDRFAFDPEKAKAALAESTYGSADKLPEITFAYSSNDTANQARHEFLANTFREVLGVEVKLQPLPSKDLSAAKKDNATYPQISLGGWIQDYPDAQNWLSVFWSSKATFAQRQGYGNPVVDEFLTKADTSTDEATRLEAYGAAQKLIVGDLPTAMMYNRVNKYVINPRVSGFSQTAADDQFPGQWTSYSIEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1M4</accession>
    <name>A9B1M4_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03909">
        <property type="protein sequence ID" value="ABX03909"/>
        <property type="gene ID" value="Haur_1261"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1261"/>
    <dbReference type="HOGENOM" id="CLU_789348_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1283-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="40814" checksum="674E348E1B7414F4" modified="2008-01-15" version="1">MNSIAAYSIFALRRFRYFIDNDNIRYLICLTITLVPFGDYILQTNTVYSIWNSLFILILLISVPVSSSKLVTIFQTIISLLMIASHGMSFIIIPFCAYFLFTRPKLLDKIYNGILLLGVLSYIITSVHPIKSQMNLSPKSFIFSLQLLFERVFFEGFFGNILRIDLVKHYPYIPISIGIIIGLTLTGLIYRWRGYLPKPIVEQFIVIGFLIIGLTIIPTITRNLISQKELIMLEPWSSNRYFYIQHMLFIILILELFYFRLMKSSFTTQNHSNHTVIVKITISICVFWIIFLNINHQKIFFGTPIYNGREVIYFLSSLDKHMHNPEKAPQPIKLERGVWSIVYTGYSALPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1P8</accession>
    <name>A9B1P8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1285"/>
    <dbReference type="EnsemblBacteria" id="ABX03933">
        <property type="protein sequence ID" value="ABX03933"/>
        <property type="gene ID" value="Haur_1285"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1285"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_0_0"/>
    <dbReference type="OMA" id="GNMIRIQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1307-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15374" checksum="C8D88E2622F90154" modified="2008-01-15" version="1">MITKLSHATIYVLDHDVAYDFYVNKLGFDVRMDMKLDNGFRWLTVGPKTQPELDLVLFEVAEGGTMMSAEVVGQMRSILQSGVVGPGVFQTADCHAAYTELQARGVEFVAPPQEQFYGIEATFKDPFGNIFSLTQPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C0</accession>
    <name>A9B2C0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1317"/>
    <dbReference type="EnsemblBacteria" id="ABX03965">
        <property type="protein sequence ID" value="ABX03965"/>
        <property type="gene ID" value="Haur_1317"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1317"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_026775_4_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1340-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
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    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
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        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="274"/>
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    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31522" checksum="AE0C11F64064330B" modified="2008-01-15" version="1">MLPETLIQQMSHGWVHAPIASLIYHRNGRAELLNRAGMELLQYQPEEAALAQQHYNLHRDPSLQAPLTKSAIASAFEGKKTRIGELDYELLNVQARPSGKHIVARLNLAPLRVEAKTGEYIVAFFTDITPQVTLRRELDSRKHEIQQAEQQQEALRAEIEARSAPVVPVLPGILVLPLVGAIDSRRAEYVLNCLLEAASEHSADTLLLDVTGIPVVDTAVANYLLQAIKALKLLGTDTIVVGISPEIAQTLVQLGLRLEDITTRADLQSGLQTALRRQGQIIRARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D1</accession>
    <name>A9B2D1_HERA2</name>
    <protein>
        <submittedName>
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    <organism evidence="6 7">
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            <taxon>Herpetosiphonaceae</taxon>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABX03976"/>
        <property type="gene ID" value="Haur_1331"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1331"/>
    <dbReference type="eggNOG" id="COG4824">
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    <dbReference type="GO" id="GO:0016021">
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    </dbReference>
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        <property type="entry name" value="holin_tox_secr"/>
        <property type="match status" value="1"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="15661" checksum="1737BE0C6A8F90A9" modified="2008-01-15" version="1">MWQVVMQWFQDWFANNATIGTLLLMMFFDILTGLLLAGQNAKINSSMSGKGMRRKAMELIFVMIGAALERFIGNAPVAESIALGFCLAELLSIIENAAKLGVPIPAPLKRVMSVLAEQAKDNSQRPDLLEQGLERIEKDGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D9</accession>
    <name>A9B2D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
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    <organism evidence="1 2">
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        <lineage>
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Schmutz J."/>
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                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX03984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03984">
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        <property type="gene ID" value="Haur_1339"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1339"/>
    <dbReference type="HOGENOM" id="CLU_2569161_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1360-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="8870" checksum="C7291A07127BE308" modified="2008-01-15" version="1">MWNVIGEIGQDTLITMGVGLPLAEALDYHHLLQTMAINAAATMQIRPSFGLITYWIEPAGEAIILDRQPMPVLTNETALAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J0</accession>
    <name>A9B2J0_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">Haur_1390</name>
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    <organism evidence="1 2">
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1390"/>
    <dbReference type="EnsemblBacteria" id="ABX04035">
        <property type="protein sequence ID" value="ABX04035"/>
        <property type="gene ID" value="Haur_1390"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1390"/>
    <dbReference type="HOGENOM" id="CLU_2093461_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1411-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="13412" checksum="D794033B71940E4C" modified="2008-01-15" version="1">MWLQLRTAESNDLLLEEDKQRLEALKKSYPQHFIRVIEKDYKNIQQVDFESVESFGAFVDRLNNGGDGVSWFTVHQNDHDIVSKIRSLKNKVHIQGNYFIGADDQNEGLLCFAIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J7</accession>
    <name>A9B2J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1397"/>
    <dbReference type="EnsemblBacteria" id="ABX04042">
        <property type="protein sequence ID" value="ABX04042"/>
        <property type="gene ID" value="Haur_1397"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1397"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1418-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="13654" checksum="496620EA30C990D4" modified="2008-01-15" version="1">MPNTLAVFLRVQLTARGWRDSQLADSAGIDRSTLSNIFKNPQSVPKLETLDRLSQALNIPLARLITVCGFDIDLRGELPEEQISILLNSLPELRSVVSDLAQLQAEDLRVIQAYIQGYLHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M5</accession>
    <name>A9B2M5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cas_Cas4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2838"/>
    <dbReference type="EnsemblBacteria" id="ABX05476">
        <property type="protein sequence ID" value="ABX05476"/>
        <property type="gene ID" value="Haur_2838"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2838"/>
    <dbReference type="eggNOG" id="COG1468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125008_0_0_0"/>
    <dbReference type="OMA" id="CPCKETV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2869-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="1">
        <location>
            <begin position="52"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19624" checksum="79882269F6A31DD6" modified="2008-01-15" version="1">MIWLALGLGLLALWLWRRSNQLRASTGLPWRTVVYHDTARRELTKALFSARYQLTGKPDYVLADGKALIPVEVKPQRQATSPRQGDILQLAAYCLLLEEATGVAPRYGLLRYAQHTFQVDWTDQLYQALLEALDAMRDDLELNDVERSHEQPWRCRACGFGDRCTDALEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N7</accession>
    <name>A9B2N7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="11" type="ordered locus">Haur_2850</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2850"/>
    <dbReference type="EnsemblBacteria" id="ABX05488">
        <property type="protein sequence ID" value="ABX05488"/>
        <property type="gene ID" value="Haur_2850"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2850"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_0"/>
    <dbReference type="OMA" id="FYYDFAY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="197"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="604" mass="68795" checksum="8CF768E237DFC6FD" modified="2008-01-15" version="1">MPPVNPDNDPLYRLRHSTAHVLAQAVLEIFPEGKIAIGPPVENGFYYDFDLPRPLTPDDLKDIEAKMRKIIKAKHRFAYREVSADEARELFKNQPYKLELIAGLAKGEDEYGEKAAASDTIISTYKHDSFEDLCKGPHVESLGDIPPNGFKLLRVSGAYWRGDEKRPMLQRIYGTVWPSKEELDHYLWQQEEAKKRDHRKLGRELGLFTFSQKVGAGLALWLPKGAILRDVLERFLRQAQIERGYLPVVTPHMGKIDLYKTSGHWYTYRDGIFPPMREIENDDTENPEGEIYLLKPMNCPHHIEIYASEPRSYRDLPLRLAEFGTVYRYEHSGELTGLLRVRSFTVDDSHLFVTPDQLEAEFLKVVDLILFVFGTMGLKDFQARVGLREVGNPKYIGSDEVWEKAQNAIINAAEKKGLNYIVVEGEAAFYGPKLDFIFRDVLGRQWQLGTVQVDYNLPERFEIEYTGEDGQKHRPIMIHRAPFGSIERFVGTLIEQYAGAFPVWLAPVQVTLVPITDRHVAYAESVAAKLNAQGLRVEVDASNNRMNAKIRDAQKLKIPYMLVVGDKEEEAGAVAVRQRSGGDLGSISVDEFIARIKDEVANYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B301</accession>
    <name>A9B301_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07464">
        <property type="protein sequence ID" value="ABX07464"/>
        <property type="gene ID" value="Haur_4834"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4834"/>
    <dbReference type="eggNOG" id="ENOG50333PI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092763_0_0_0"/>
    <dbReference type="OMA" id="ADPREWA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4893-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="28853" checksum="7F5FDCEEFD220F5D" modified="2008-01-15" version="1">MSLVLASAWQPRGELARFERLLPQLSQLYRAIVITTPPTIDAQLLQSLNELPNVKAVPTTEWFQGRHLALAEALKTQPNYIHAIDFDRALRWIETRPSELTSIAQRSQTHCLIIGRTWQAYATHARALIETERTSNTMASFFLGMPMDISAGARGFTPVAAHFILANSPPLDALGTDAEWPVLLHRGGFKLNYCEVDGLDWEIPDQFQAQAADAEAQQSQAAHYDSQIEHWRYRVEVAQRIVQAGIAAARRPLQFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N1</accession>
    <name>A9B3N1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="7" type="ordered locus">Haur_2965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2965"/>
    <dbReference type="EnsemblBacteria" id="ABX05603">
        <property type="protein sequence ID" value="ABX05603"/>
        <property type="gene ID" value="Haur_2965"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2965"/>
    <dbReference type="eggNOG" id="COG1921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038142_1_0_0"/>
    <dbReference type="OMA" id="GATNRTH"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="446" mass="47408" checksum="A883466D292E43B2" modified="2008-01-15" version="1">MSLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAVDLILQRQQPPLRHVINATGVILHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGSRNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQEVIVSRGHAVEIGGGFRIPDILRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAHEHQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKRQLIDQLRKHPLLRALRVDKLTIAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALPLLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEALSKQLRANDPPIVGRIQAQRLILDLRTVLPEQDAVLMAALAALDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P6</accession>
    <name>A9B3P6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2980"/>
    <dbReference type="EnsemblBacteria" id="ABX05618">
        <property type="protein sequence ID" value="ABX05618"/>
        <property type="gene ID" value="Haur_2980"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2980"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_361226_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3012-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="774" mass="82553" checksum="4E275D55E88E9C48" modified="2008-01-15" version="1">MMSRRAGMLIIAILSLALLVGLIGYALLVQPVVAQLSPTPPTLFTQLQYPFNQSLIPVGKVLTVHSRSWGSQPIENVELWADGQPWALQAANNATLYEGLFAWQSLGLGDHSLVARTNDTSKIPSTSAIVRLNAVMPYEPVATFQVQQSAGESLESLSKAFDVAPQTLLKLNPQLGNLPLNQPLGSDQSITIQLAGQFTPISTTTSLSATQTPLPADVANLPLATPYDPNAIWFDLQRRFGTANVPLAPEALVGSSNCQTQLVFTPTSDDADGFFIYRAGPTQNHFELVATVAANGSGPQLWQEPADFGQTLYYVVAFNPAGAAASPVVALENADSACATLQVPQFASLLLTPKIAVSDVYCYSSLANGPWQRVPNQGFLLPIAGGYDLASALPLTAISASQTWNLECWGWNGTQPQLLGNTSTTLSLGQEQIIALDADLFSLQGQLNTSTQIQQVPTLSTIAPPTNLRLTTDLEECVQAAPQADDFWRTACSTNLAAGATVLTWQWSEQACFPSADGQDCSANANLEGFQINDRLAGTPLELTRVNPEQRLVFLAPRTMPSPTDECLSVQAFRGLAVSLDSEVLCLPALKLAAGSYTLAPSLFNLNAGVAQQTVGDGCPALPINQSQSTSLNYPYVSSLLLLQRNAVAETACRRYTASWFDGSVSFILPRLDQSVGGLELSFSVASQPEPANEACPASASLQIGSASQTIDLATWPTNGLVTVAVDQALLEQIGQSNDPKLNFTLQAERQLANRNQRCSSELGDFSLKLTVQP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B440</accession>
    <name>RL13_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplM</name>
        <name type="ordered locus">Haur_4943</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B440"/>
    <dbReference type="SMR" id="A9B440"/>
    <dbReference type="STRING" id="316274.Haur_4943"/>
    <dbReference type="EnsemblBacteria" id="ABX07573">
        <property type="protein sequence ID" value="ABX07573"/>
        <property type="gene ID" value="Haur_4943"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4943"/>
    <dbReference type="eggNOG" id="COG0102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_2_2_0"/>
    <dbReference type="OMA" id="DFVVIIN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000144140" description="50S ribosomal protein L13">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <sequence length="144" mass="16380" checksum="FEC03D0C78FDC074" modified="2008-01-15" version="1">MKTYSQKASEIQREWLVVDAQNQVLGRLATQIATLIRGKHKPTYTPSMDGGDFVIVVNAEKIRVTGDKANQKIYYRHSNFPGGLKRTAYKVMMQTHPERIIYFAVKGMLPRNRLSRHIIKKLKVYAGESHPHASQSPKVYAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B474</accession>
    <name>A9B474_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Topology modulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4977"/>
    <dbReference type="EnsemblBacteria" id="ABX07607">
        <property type="protein sequence ID" value="ABX07607"/>
        <property type="gene ID" value="Haur_4977"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4977"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092618_0_1_0"/>
    <dbReference type="OMA" id="WIWEYPN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5040-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="20486" checksum="09E1BBBC400857CD" modified="2008-01-15" version="1">MKAIRRVLIFGSMGSGKSTLTKRLGAVLKLPVIHLDSHFWRPNWVEPDRETWRAQQRELVQASEWIMDGNYSATLDERWPYADTIIFVDQPRLLCLWRVVKRRIMYHGRSRPDLAPDCPEKLDRVAFEFVWTYPKARRPKVLKRLAEAKTTKLVFHLRGDAAIEQFLVDLSQIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I3</accession>
    <name>A9B4I3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1504"/>
    <dbReference type="EnsemblBacteria" id="ABX04148">
        <property type="protein sequence ID" value="ABX04148"/>
        <property type="gene ID" value="Haur_1504"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1504"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_0"/>
    <dbReference type="OMA" id="FWGEFAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1526-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="35453" checksum="5A00BD5D1BCB73CC" modified="2008-01-15" version="1">MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGLFKPKKGIPGTDVAGVIEAVGRNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPEQLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGGIGTFAVQLAKHFGAIVTAVSSAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVGGEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEEAPAAMRYLQAGHAKGKIMIELQPTTAQSLEQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J4</accession>
    <name>A9B4J4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04159">
        <property type="protein sequence ID" value="ABX04159"/>
        <property type="gene ID" value="Haur_1515"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1515"/>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_448219_0_0_0"/>
    <dbReference type="OMA" id="RAENAYI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1539-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012564971" description="Beta_helix domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="211"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="586" mass="63806" checksum="369B11A6EEB31C45" modified="2008-01-15" version="1">MALFLGLLLAQVGVAAPQSAVVAGELRADATFSHIGVSWAISGDTNRNSTLTLEYRLVGSSTWRAAAPAMRANPSTIVEGVALNRNYHAASAMWLSDGEEYELRATLTDPDGGNTTRTITKRTRSLADFGPTVRTRFVVPGNGGGDGTLNNPYQGIQTAVDNAEPGDTFTLAAGTYQPFQILASGTQAQPIRISGPLNRKAIIDGANTTRGVVTLGESNQTLGFVILENLTIQNGAWGIDAQHTHDILISRNVIRDVGFGIYNRRQTHQEYNQTVIDNVITGRTTWPGTGIPSERGLDLRGTGNVVAYNSVMNFGDCISVQPWNAQSSYGQDIYHNEAAFCVDDGIEIDYNQANTRVWNNRVTNARTGVSIQPIYGGPAYMFRNNFFNIAGAPFKLHNQPTGLFIAHNSSARIGNALSDDGQQWRNTIIRNNFMLGTRYAFEFMTIADEGFRDVDYNGWGTNHASDSPSAPDFKWNNERYLRLSNLQQIGVETHGVTVSFNDVYNATLPASVDVASPIGEADLRLQNSSVAINKGAVIANLNDPFVTDGQPDLGAFELGKPLPHYGPRIDYQIPSNIRVYLPLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R7</accession>
    <name>A9B4R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3002</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3002"/>
    <dbReference type="EnsemblBacteria" id="ABX05640">
        <property type="protein sequence ID" value="ABX05640"/>
        <property type="gene ID" value="Haur_3002"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3002"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="IMMQKIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3034-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="25514" checksum="906543D353064250" modified="2008-01-15" version="1">MLQLQNVHTYYGNIHALKGISLEINQGEIVTLIGSNGAGKSTTLRTISGITPPRTGQVLFEGKPLNGVPAHKIVSQGISQSPEGRRIFANLTVRENLEMGAFTRNDKAEIASDMDRVFELFPRLKERVVQRGGTLSGGEQQMLAIGRALMSRPRLLLLDEPSMGLAPVLVDLIFEIIQNINSQGTTILVVEQNALMALGIAHRAYVLQTGAIVKAGDAATLREDEDVQKAYLGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V2</accession>
    <name>A9B4V2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3037"/>
    <dbReference type="EnsemblBacteria" id="ABX05675">
        <property type="protein sequence ID" value="ABX05675"/>
        <property type="gene ID" value="Haur_3037"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3037"/>
    <dbReference type="HOGENOM" id="CLU_979243_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3069-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735453" evidence="1">
        <location>
            <begin position="24"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="31498" checksum="1D5B9EF7777A4A09" modified="2008-01-15" version="1">MKFARILILLLLIHGILPQASFANPDAPTAATLAWSSAYASTAEGIDVWLRINVVGAAPTDDVNLKFIYQTFQQTAEYNHDYEPTNWPSGTKGAIVGNNRVAYIKIHIKKNDYPEPTETFQVELRSDAANTVISGPARVTVTIRRSRLMNPIAGIMESCVNGGEPNNDFPASAGQIAVNGGWCNTSFETEAVRDVDYYHVEQSTAGNITIRLENTTPDQHDLNIYLYYRDVQEGYKLYLQSTNPGQQAEVISNAPIAANTNYLIAVYWASDTGDKIPTYRLSVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V7</accession>
    <name>A9B4V7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3042"/>
    <dbReference type="EnsemblBacteria" id="ABX05680">
        <property type="protein sequence ID" value="ABX05680"/>
        <property type="gene ID" value="Haur_3042"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3042"/>
    <dbReference type="eggNOG" id="COG1600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030790_0_0_0"/>
    <dbReference type="OMA" id="ICDTDLS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3074-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="183"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="383" mass="42504" checksum="F20C70F0A8F410E0" modified="2008-01-15" version="1">MTNNLAEAVRAQAAQLGFNLVGITPAKPSPTLAAYQAWVEAGMYGEMGYLARPDRQARRQDLNVIVPNVRSLIIVALDYRTQPIPASLLNDPSRGRIAAYAWGIDYHDLMTPRLQELANWLQAQIAEPVQQRVYVDTGAILERSHAQQAGLGFIGKNTMLISPRRGSFFFLGEILTTYEFADYDQPAPPTMCGSCSRCLQACPTKAFPKPHVLDARRCISYLTIEYKGSIARELRPQMANWIVGCDVCQDVCPWQRFGVQSQESAFFPIDHDRAAPPLASLLTLDPAGFGERYGEAAISRLKRDRLVRNACVAAGNWRDPAILPLLAPLLHDASSLVREHAAWAIGRNFDDSSVMLLQQALQTETEPSVRNELQQSLHERSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B508</accession>
    <name>A9B508_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3093"/>
    <dbReference type="EnsemblBacteria" id="ABX05731">
        <property type="protein sequence ID" value="ABX05731"/>
        <property type="gene ID" value="Haur_3093"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3093"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2023530_0_0_0"/>
    <dbReference type="OMA" id="HRIMVAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3125-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="12773" checksum="E5D7072D75C87F02" modified="2008-01-15" version="1">MSTIVAYVPDLMFGVRVRDVLQQLGYQALVADSLAAAQQALAPDLALLIVDLRGETTATSALVKAAKALDPNLPVLAFGSHVDVERQKAAREAGCDKVVANSKFSSDLPGLIATLVRQPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B523</accession>
    <name>A9B523_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3524"/>
    <dbReference type="EnsemblBacteria" id="ABX06160">
        <property type="protein sequence ID" value="ABX06160"/>
        <property type="gene ID" value="Haur_3524"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3524"/>
    <dbReference type="eggNOG" id="COG5646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119457_0_0_0"/>
    <dbReference type="OMA" id="YGMIGYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3561-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="22"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="17094" checksum="A97BED87B2B5FCC9" modified="2008-01-15" version="1">MQSKATTVEQYLAELAPERYSVIEPVRQLILQHLPEGYVETCNWGMLSYEIPLERFPNTYNRQPLSYIALAAQKNYNSLYLMPVAYDEPYAAWLQQQFSQAGKKFDMGKSCLRFRKLEDLLPDVIAQVIQRYSVDDYIGYYRAMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B535</accession>
    <name>A9B535_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3536"/>
    <dbReference type="EnsemblBacteria" id="ABX06172">
        <property type="protein sequence ID" value="ABX06172"/>
        <property type="gene ID" value="Haur_3536"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3536"/>
    <dbReference type="HOGENOM" id="CLU_2154883_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3573-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="13064" checksum="7AEE795FF4F3B91C" modified="2008-01-15" version="1">MRLSLFIILLASLLIGPALLMKFYYFERICQTYAQAHNFESSRYSPSSKNSPEQCFFEGQRPVLVKQIVGWKHRIILVVWLLYQPFGAFGLTFGIFLAPWEKLKWFKNSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D0</accession>
    <name>A9B5D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0103"/>
    <dbReference type="EnsemblBacteria" id="ABX02755">
        <property type="protein sequence ID" value="ABX02755"/>
        <property type="gene ID" value="Haur_0103"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0103"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005071_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-104-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="168"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="634"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="676"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="718"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="760"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="801"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="843"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="885"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="968"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1010"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1052"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1134"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1209" mass="135847" checksum="87100E6C359C3D79" modified="2008-01-15" version="1">MTNVVLSLPVFHATEGLGAFLGDLRSWVFRSKNRAARHFGLAHTTIMRYENDQILCPLGYIAALAQLVIEQLDLPPYQRGLAEQQLLATIQYALTEYAIDHTPLATWPELTNLAAAYLAEVQQQKQEQAKTGPLMGVLHDWGDAPDVQNFVGREDETATLVKWLQLDRCRLVAIIGLGGMGKTSLATRVAQQAQDDFKVIVWRSLQQGQQANDFLLECLHRIMPSPNSAYPSQFEHRLSVLIDYLRTTRCLLILDNIEAILQPQYPAGRYREGYEQYAQLFQAISERSHESCLILTSREKPYEFNRLEGVHTRSMVLTGLMRDDAQMLLDNQELYGTPQLWQELIKHYTGNPLALKLVAQVIKTMFFGQIAEFLQHEELIFGDVRTILAQQFERLSDQEQELLYWLAIERHTVKLAELKHDLVRSKYQHMLLETLESLLRRSLVERHQDGFMLHNVVLEYTTDRLIDQIAQELLDGTQGLLYRHALIKANSLDSIREHQSRAILRPLLHRIFVELGQERLLASLRQLLQTMQPLSALEMGYAPGNIFNLLVELKADLSQFDFRHKPLWHANLRGINPKQLDLSHSDLSRSVFSEQFGALIALARDPADRFLAVATADDQLIVWQNLDLKKLWQVPSNHDGIRAICFSGDGRYLISAGNDGLIRLWETSQGQNPRILAGHTRPVIGVAIAPQSQQLISASLDGEVRLWDRLSGKCLHRFNAHADGLSSIGLSANGQYLATAGLDRQIKLWHGPQLNYQTTITTHHEPIEILAFSPNPTILAGTGLDGDVYLWDLQANQLITSLPNEDRVFDLQFSPDGANLATAGLDQCIRIWQVETAHLTHMLYGHAHWVRALHYNRDGSRLYSVSSDQSLRIWEQASGRLLHTLQGYRGGVRSLALSNNADLLFNAGEAQAVTLWQLAEPFYRLNLPQATNNGRELAYHQASQLLAISQEQVIQLWDCQRLQLATILTGHQALIRAIAFRPDGSMLASCSEDHTVHVWSMPHGQIVQVFGCHDDLVTTLAWSQNGSLLATGSADRTIRIWGVAEHSCLSLLAGHSAGIISLAFSPDQRHLVSAGADQQVRIWDLSNQCYEIVLLHKPGLLKAVQWSADGRWIVIAAGSLALIWDWQNQQLVQRFEHQAAVDSICLSSDGHMLITGDQQGAIAIWQLATGKLLKKLHSDRPYQGLIINQAIGLNAAEQASLLNLGALIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J7</accession>
    <name>A9B5J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0170"/>
    <dbReference type="EnsemblBacteria" id="ABX02822">
        <property type="protein sequence ID" value="ABX02822"/>
        <property type="gene ID" value="Haur_0170"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0170"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049749_2_1_0"/>
    <dbReference type="OMA" id="KERPMIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-173-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="58"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="29354" checksum="DBC577864C39A47A" modified="2008-01-15" version="1">MSANSEWPELNAQSNAVWETNAEHWDNSMGQDGNRFHLQLVRPAMLSLLELQAAQRVLDIGCGNGLFARHLAELGAMVLAVDASTSLIERAKQYPNPATLEYQVVDATNLAQLLALGASSFDALVSTMVLMDLPTIEPLFQAAAKLLKSQGRFVLATVHPCFQTPHNRKIVEQFENAQGEVETHSRLQIGNYLTPTVHQGVGVAGQPSAQFNFHRSLTSLLGIAFAAGFVVDGLLEPRYPTGTTSTHPFSWANFSEIPPVLVLRLRLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K4</accession>
    <name>A9B5K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1594"/>
    <dbReference type="ESTHER" id="hera2-a9b5k4">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04237">
        <property type="protein sequence ID" value="ABX04237"/>
        <property type="gene ID" value="Haur_1594"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1594"/>
    <dbReference type="eggNOG" id="COG2382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024314_1_0_0"/>
    <dbReference type="OMA" id="DFQDWRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1618-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735467" evidence="1">
        <location>
            <begin position="21"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="409" mass="45719" checksum="4D2B849137F292BB" modified="2008-01-15" version="1">MQRFMSLFLICALLASCGGAAVSYDPTQPITSFNLLREQLAKTNDQAEQLKLINDFNAVFPTSPLTQGDQALFMVEKDAPRMELSSDLTNWFQTTSMQRLGSTNWWGLVQTISSTARIDYRFGVGGGGGLMNDPRNPTLVPSSMGMNSELRMPEYLTPTEIISRSDVPKGTLEDLGDYYTDISKTTHRLHVYLPANYDPAKQYPSVYFQDGDDYQNYAFTPTILDNAIADQILPPLIAIFVKPSREQGRQRDYDLNDAYSEFFATELVSLIDSKYSTINDPKQRVVVGDSYGGLISLYLALQYPEVFGGVVNQSGFVSRQNGRLLTLMSIQPPVNARIVTVVGTYETCIGGPVTGDECNFLEGNRTLRDILVGAGVQLNYAEYPQGHAWAFWRDHIDREVAWALDWQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q8</accession>
    <name>A9B5Q8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_C25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1648"/>
    <dbReference type="EnsemblBacteria" id="ABX04291">
        <property type="protein sequence ID" value="ABX04291"/>
        <property type="gene ID" value="Haur_1648"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1648"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_326456_0_0_0"/>
    <dbReference type="OMA" id="LSAPENW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1672-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029031">
        <property type="entry name" value="Gingipain_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732491" description="Peptidase_C25 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="3">
        <location>
            <begin position="467"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="865" mass="95934" checksum="BD2B784DF04EEA83" modified="2008-01-15" version="1">MWRYLALFGILCSFAFNPPQHASAQPAIQTRATINETPNGLQIEWQAAKAVRPFAVLVADAWQFQPTLQALSLDHQNINQLADLPAPIIVLREGRFRGQRLVVLQPQTTFNQQAITQATVSVSNAQLLNDPHRLIDQPFQLTQSVPSPQSGQGWRVVVNQAGMQQLTGASLEQAGINLATLERYSLQLWYKNQQLAIEEQGTLDGSFDRNDAIWFYQPSVGDRWNTTSSVWLKIGVAHSSPKIQQISIDPTGLPTSNQAYQTSTWYAPKIYDSLQAGNDGDHWFSADLKAGPDLNPITQQIWLTSTLPLATGPSTVTLSGIVYTSAVTSVAITSSQRINLNLNSGIFTKSAQLAPSQNLQLAIASTQQISGISLDRLVWQRPVLLNANYQSFQWQALRKANYQISNQPNQAVSYNVSNPWQPQRMQFQNNTLAANPGDYLLVNPTNLPQPSIQASATVNWATPAKTIYLAPKQWHSLVQPLINRRQQQGWQPLLVDVQAIYDRWSSGNVDPLAIRDFMRYLASTWPQAPQSLVLVGDGTIDPLNYLGRNNPNMIPPLPAYTDPWLGEIACDTCFVQLDGANPLDDPMPDLQIGRLPAKTSTEVSNLINKINAYENAPADLRWRSRQVYIADNYKTANGQADYAGDFAALSDIMLSYQPSQLDIQRIYYDPWRKTNNGLPQTDPWRITSADQARQKTFEQLNQGAAVVTYVGHSHQYQWAITDLSNNQPYLLSLYDSDRLQNSPALPMILEMTCLTSAFQTPAWSGTSLDERLVLQPQGGAIATWGSAGLGVAHGHDLLNAGWWQRMWSNPSQTPIGTGVLAGLLHLFSDGGCCQDSLQSSILLGDPNILLQHQERQAIYLPAIIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V4</accession>
    <name>PRMA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="1">L11 Mtase</shortName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prmA</name>
        <name type="ordered locus">Haur_3109</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5V4"/>
    <dbReference type="SMR" id="A9B5V4"/>
    <dbReference type="STRING" id="316274.Haur_3109"/>
    <dbReference type="EnsemblBacteria" id="ABX05747">
        <property type="protein sequence ID" value="ABX05747"/>
        <property type="gene ID" value="Haur_3109"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3109"/>
    <dbReference type="eggNOG" id="COG2264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049382_0_1_0"/>
    <dbReference type="OMA" id="EFFFIFP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000132802" description="Ribosomal protein L11 methyltransferase">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <sequence length="321" mass="35192" checksum="187D54F7E33717C0" modified="2008-01-15" version="1">MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYLLANEQAADAQTQIERGLWVLGMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVPSWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELIEFNNTTVLDLGCGSGILAVGAAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGTPQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVGLEQVERRTQGDWVAFTHRKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W1</accession>
    <name>A9B5W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3116</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3116"/>
    <dbReference type="EnsemblBacteria" id="ABX05754">
        <property type="protein sequence ID" value="ABX05754"/>
        <property type="gene ID" value="Haur_3116"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3116"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="SFYKKDC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3148-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="36188" checksum="54781A563DB00A2B" modified="2008-01-15" version="1">MIIAEELRKQFGDFHAVKGVSLEVKPGEVLALLGPNGAGKTTSIRMLAAILKPTSGRAVVGGFNVETHAREVRHAVGLLTEFPGLYHRMKSLDYLLFFGRLQGMNDRDCGNRAVQLLQQFGLWEAREKRIDGYSKGMKQKLALIRAMIHDPNILYLDEPTTAMDPHSARTVRDAIAGLRSAQRSIILCTHNLNEAEELADRIAVVHDGGIAVQGTIAELSQQLMGDPIWELRLAQPQPELAQRLADLLTIEEVGDSWLRYRTTEPQTLNPVLIQRISGWGWPLLAINEVQRSLEDVYLTIVGQTHRERMSSPLEQPNAAAVAEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B677</accession>
    <name>A9B677_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAM hydrolase / SAM-dependent halogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3652"/>
    <dbReference type="EnsemblBacteria" id="ABX06288">
        <property type="protein sequence ID" value="ABX06288"/>
        <property type="gene ID" value="Haur_3652"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3652"/>
    <dbReference type="eggNOG" id="COG1912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059734_1_1_0"/>
    <dbReference type="OMA" id="EIPYQKA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3691-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002747">
        <property type="entry name" value="SAM_Chlor/Fluor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023227">
        <property type="entry name" value="SAM_OH_AdoTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023228">
        <property type="entry name" value="SAM_OH_AdoTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35092">
        <property type="entry name" value="PTHR35092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01887">
        <property type="entry name" value="SAM_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006779">
        <property type="entry name" value="UCP006779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101852">
        <property type="entry name" value="SSF101852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102522">
        <property type="entry name" value="SSF102522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="29970" checksum="FCBC12B1CC4EF974" modified="2008-01-15" version="1">MQPNGILTLTTDFGSVDAYSAVLKGVILSVNPQATLIDVTHEIDAQRIAQAAYLLHTGYRYFPDGTVHLVIVDPGVGGDRKAVALCSPRWAFVAPDNGVLSYIWKDLVAEFGREQLQLIELTDDRWWLPKVSATFHGRDIFAPVAAHLSKGVQPEELGQPLAELIDLPLAEPRQRPDDAWEGRIIHVDNFGNCITNITRDFIAQHGGIEQVEIGILDQQIGRICRTYADSEWGMVMALFGSSERLELAVRNGNAARMLGVGIGDSLRIRFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D2</accession>
    <name>A9B6D2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ordered locus">Haur_0183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0183"/>
    <dbReference type="EnsemblBacteria" id="ABX02835">
        <property type="protein sequence ID" value="ABX02835"/>
        <property type="gene ID" value="Haur_0183"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0183"/>
    <dbReference type="eggNOG" id="COG0320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033144_2_1_0"/>
    <dbReference type="OMA" id="GRCPNRG"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="50"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX02835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="34288" checksum="94AA78781155E66D" modified="2008-01-15" version="1">MPSTPHRQRKPEWLRKPVLSPELRNVRQLLRDLNLNTVCEEASCPNIAECFGHGTATFMIGGDRCTRRCHYCDVTTGKPFPLDPREPSNVAEAAARLGLKYVVVTAVARDDVKDGGARHFARTISAIRQRLPEAEVEVLIPDFKGEAEALKTVLDAEPHVLNHNIETVRSVFKSVRPQGDYDRSLELLARSREFAPQITTKSGFMVGLGETTDEIYQTMDDLKHVGVELVTIGQYLQPSLNHVAVSEYIPPERYGLYRDHGQQLGFRATFAGPFIRSSFHAGELQHHQPSSDVASPVQEWIALEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I5</accession>
    <name>A9B6I5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0236"/>
    <dbReference type="EnsemblBacteria" id="ABX02888">
        <property type="protein sequence ID" value="ABX02888"/>
        <property type="gene ID" value="Haur_0236"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0236"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_0"/>
    <dbReference type="OMA" id="THTSMRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-239-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="39239" checksum="9038A3F98BE3AE52" modified="2008-01-15" version="1">MSLGVGSVLLGRYQILRLIGQGGMGTVYAAFDQQLNHQVAIKYFRGQDATFQSNLQREAQILARLRHPSLPRVYDLQRVGDAAFLIMDLIEGENLDTLLFQRGAAFEPDVVLAWAKALAPALSYLHYQTPPVIHRDIKPQNIIRTPDGQLILVDFGLAKQWASSNQSVVAYTLAYAALEQIQATSPVNQRSDVYSFAATLYHLLTNCEPADALTRASSLINGQPDPLVNPVNLNPAVSPAMAAVLAQAMALPAHERPASIDQFIQQLQQSFYNQPSLMSSAGQPTIVQRPAVATIVLPTATKPALSAQQILQPQVPPQQITYQEKSESSLNLEQLWTFLMVLLFLVGLMVWITNAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I9</accession>
    <name>A9B6I9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0240"/>
    <dbReference type="EnsemblBacteria" id="ABX02892">
        <property type="protein sequence ID" value="ABX02892"/>
        <property type="gene ID" value="Haur_0240"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0240"/>
    <dbReference type="HOGENOM" id="CLU_1018512_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-243-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30600" checksum="BDECBA3472B0B4B3" modified="2008-01-15" version="1">MMKIQWLNFGRTLIVGILFGLWCAVLGGAIGFWLGESASYLLGVIAGIASIFLFVRLSHRWINHTLLGVICLLNIGTLIGTAIGTSSERLYYGQVQIDNIRAEQISQHPEAMIFTLEQAVVQHEYGVTFAYTTSDARRSSTTWHAISVAPLTSPDWQPDQPVPAWAVCGGYFEYECEEWQQPIKAALISKPTNQNPQQTAITKNLDTHGYSAIENAPRLYVGSSVESLMADHRFIWRSTWLFVNGIWAVPFFIFVGAELLWNTLKQLFTKKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R2</accession>
    <name>A9B6R2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1728"/>
    <dbReference type="EnsemblBacteria" id="ABX04371">
        <property type="protein sequence ID" value="ABX04371"/>
        <property type="gene ID" value="Haur_1728"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1728"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_2_0_0"/>
    <dbReference type="OMA" id="NAELCNA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1755-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="803"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="870" mass="96681" checksum="A1EC53DB34D01383" modified="2008-01-15" version="1">MVMPILTTKCYIPVPRLNGVVRSQLLERLKERHDRRLTVVSAPAGFGKTMLVSQWIANCKQPVAWLTLDQNDNDLARFLVYLVAALQTIEPTFGLEIIQRLQAPELPSTETILFLLLNQLATIEQQSILVLDDYHWLTAKPIAEAMRLLLERLPPQLQIVVITREEPDLPLARLRARHQLTELRVADLRFTVAEAHQFLSQTMELDLLASASQALTDQTEGWITGLQLAAISMQGQQASSPLIDGFTGNHRFVLDYLLEEVLQQQPAEIQTFLLVTSLLDRMCGSLCEAVLAAAPASGAATLAYLERANLFIVPLDHERHWYRYHHLFADLLRQRLAISSLGHDLPELHRRASHWYEAHGFGIEAFRHAAAANDVAHIERLIDQQQISLHFRGTVTTLLDWLATVPKSVFEQQPSLWWRHASLMLMLGQTSGVAEKLAAAEAALQSFPDDHQTRNLIGQIAASRAILLLAQYQFASTLAQSQRALEYLAADNVFSLTSAYWTLGFGYLAHGDRAAARQALTKSVSLAQASGSSFIRILATIGLGQLQESENQLYQAAATYQQILALAGEQPLQIIYEAYLGLARIYYQWNQLDAAERYAQQSLDLAQQYDRLIDRSIICEIWLVRLQLARRANEQAATKLGQLAQTVRQQNFTQRLPEIITTQIGVLLAQAELQAAAELAQTIDSPLIQAKVLLAQANAAAALELLQPLIEQFQAKGWLDQQLHGLILQAVAQQQQGQKAPALRTLQAALAMAEPGGLIRIFIDEGPELKQLLRELIGRGLGNAYARQILAAFGQMPLMPSAQVALIEPLSERELEVLGLIAAGLSNQAIADQLYLSLYTVKAHVRNIYGKLSVNNRTLAVAKAQELAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6U1</accession>
    <name>A9B6U1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol kinase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1757"/>
    <dbReference type="EnsemblBacteria" id="ABX04400">
        <property type="protein sequence ID" value="ABX04400"/>
        <property type="gene ID" value="Haur_1757"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1757"/>
    <dbReference type="eggNOG" id="COG1597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045532_0_0_0"/>
    <dbReference type="OMA" id="GFDSRVN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1785-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="32227" checksum="F6637B481239A2E6" modified="2008-01-15" version="1">MTKLRLAVILNPHSNRQRAARQAPHILAMLEHFGLEATLLQTTQVGHATHLAQQCVAEGNWDGIIVAGGDGTINEIVNGMAGSSMPLSFIPLGTGNDFVKMLKLPTNNTVEAIRAIAANRLRQIDLGIINQHWFINGVGIGLDANVAIEAQKLKRIKGGLVYMIAVLKSILHYQARDLLIETDDLTLQKRINMATVGNGGYHGGGFWITPESQIDDGMLDVCLTGEQSRWSMVRDSSRVRQGSHTNLPSVTMLKTRTFKLYSERGVPVHVDGEVFSASLHEITITIQPAALTIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Y4</accession>
    <name>A9B6Y4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit J</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3215"/>
    <dbReference type="EnsemblBacteria" id="ABX05852">
        <property type="protein sequence ID" value="ABX05852"/>
        <property type="gene ID" value="Haur_3215"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3215"/>
    <dbReference type="eggNOG" id="COG0839">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085957_4_0_0"/>
    <dbReference type="OMA" id="YTYYFVW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3250-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001457">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00499">
        <property type="entry name" value="Oxidored_q3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0874">Quinone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="174" mass="18477" checksum="7EF79ECD1431AA21" modified="2008-01-15" version="1">METFLFITTAIVAVGAALAMVLSSNAVHSALFLILNFCSVAILYFLLRAPFLGAVQVTVYAGAIMVLFLFVIMLLGAENAELGEEKIGWQKPAGLVLGVALLAEIGYVAYRGTTLIDAPVADATNIGAPTTISAKLFSTYLLPFEVISILLLIAVVGTVVLTRRRVVAREESQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B709</accession>
    <name>A9B709_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="2 4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpF</name>
        <name evidence="6" type="ordered locus">Haur_3240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="2 4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3240"/>
    <dbReference type="EnsemblBacteria" id="ABX05877">
        <property type="protein sequence ID" value="ABX05877"/>
        <property type="gene ID" value="Haur_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3240"/>
    <dbReference type="eggNOG" id="COG0135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076364_2_0_0"/>
    <dbReference type="OMA" id="FYAKSPR"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="9"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="23524" checksum="649033546FE8AC39" modified="2008-01-15" version="1">MSWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPCQLVGVFANASAAEINQLAQQVGLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWYDIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTTPLLLAGGLEPNNVAQAIQAVAPWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B722</accession>
    <name>A9B722_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3253"/>
    <dbReference type="EnsemblBacteria" id="ABX05890">
        <property type="protein sequence ID" value="ABX05890"/>
        <property type="gene ID" value="Haur_3253"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3253"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_599606_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3288-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="46052" checksum="8A2CD2F312357899" modified="2008-01-15" version="1">MSADIIANHYEAVEQAGVRFKKLYDYQVQMETMIRQMYEQLRNDGWQGTAAQAFFVEMTDVVFPTLQRLQNTLLVSSELTKQINQIFRQAEEAAAKCITFDSGSIGGMLADAGLAAGHGLAGVSIGAALFDDTSKPDLRKTIFNDDYMNRLVGLKMQGMDVPELNKAMETIINDKASEADVQAALVKIAKLRDVPLEKIQADHKRFVELRKRATEKGDVDQLDQDRHPDFLGSTTSLRFGKVLGDVFGIDPVFGSLLSPTGGLVGYGNIAIDAKERPVGYHGIMHDAGGYLLKHHEMGPGYDYLGLEGRNPTHPLTGQESGIRYWNQKLAYGFIDGDGINLNNPVQKLAEYAVIDAVDHRLGQIVDVHEGLKTVKNAANDGWNAAKDAANDGWHATKDAASDRWNAASKSAKDIFSFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B789</accession>
    <name>A9B789_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3736</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3736"/>
    <dbReference type="EnsemblBacteria" id="ABX06372">
        <property type="protein sequence ID" value="ABX06372"/>
        <property type="gene ID" value="Haur_3736"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3736"/>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1872604_0_0_0"/>
    <dbReference type="OMA" id="HESIVDP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3778-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731949" description="Cytochrome c domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="14554" checksum="6C40A20F575D84FF" modified="2008-01-15" version="1">MRRFGYFVVGLLLLGCGAANDSTSVGNAERGKRIFQGAEVLTLDQLEACVDCHSDVAGEAGQGIGQNLSNIGNRAAQRPDGTSAIDYLRLSLTEPDKELVGGFQEGIMPRDYAQKLSTQDINDLIGYMLTLKSGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B799</accession>
    <name>A9B799_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3746</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3746"/>
    <dbReference type="EnsemblBacteria" id="ABX06382">
        <property type="protein sequence ID" value="ABX06382"/>
        <property type="gene ID" value="Haur_3746"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3746"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OMA" id="RDRQFLG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3788-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38810" checksum="AE881525597C1354" modified="2008-01-15" version="1">MLHMQGIRKQFEQTIVLREIELTINRGEILALLGPSGCGKSTLLRIIAGLESADQGQLLLHGQPLNPIPIHRRNFGLMFQDWALFPHRNVGENIEFGLRMEGMAKLQRQQRVAEMLELVGLVGYQQRSVLELSGGERQRVALARSLAPRPQLLMLDEPLGSLDRTLRERLTEELRRIIKAAEVTAIYVTHDQNEAFVVADRLAVMNAGQIVQLDTPQAIYQQPKTAFVARFLSLTNLLPIVKQTSLSPELQLVETNLGQFEIQSSQTQAAYLLIRPEAAQLAPSATASYRGQVVGQSFRGSHQRIEWRYAHGGLQLDLPSNYQLDQGQNLDLTFDAQQLSLVQSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F1</accession>
    <name>A9B7F1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0272</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0272"/>
    <dbReference type="EnsemblBacteria" id="ABX02924">
        <property type="protein sequence ID" value="ABX02924"/>
        <property type="gene ID" value="Haur_0272"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0272"/>
    <dbReference type="eggNOG" id="COG5478">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072266_2_2_0"/>
    <dbReference type="OMA" id="DHTLREK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-275-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007251">
        <property type="entry name" value="Iron_permease_Fet4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04120">
        <property type="entry name" value="Iron_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="16222" checksum="C784DEB97AC2C564" modified="2008-01-15" version="1">MYSVKTKSRFTQVSKWTAHITGRPRTFGLAVGVIFLWMISGPLFGWSDTWQLVINTSTTIITFLMVFLIQNTQTRDSEAIQIKLDELIRATQGAHNALLDLEELEEDELDQIRATYQRLSERAREAIRHGLVDTDNPEPEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7G6</accession>
    <name>A9B7G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02939">
        <property type="protein sequence ID" value="ABX02939"/>
        <property type="gene ID" value="Haur_0287"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0287"/>
    <dbReference type="HOGENOM" id="CLU_851982_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-290-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="37162" checksum="5E2FC7EFFA4A9E7F" modified="2008-01-15" version="1">MSTNIDHHIGVEITFDQNPSRTHFAHYYYRAELYYGVDDKQAWCFTMLLDEDRHVMPGETVQACLWFLSPQYQLGQLTVGTPFWLRSAQRLDGTGHVTQITNLEQAVRAKSKYDLPVEVTFLAMPANNPSQVYSLFYGKHLNEYDLHNGYIKLAAGHTSIATKPKHIPVPFEITAITLNQSEINNQPWFTEQHQWMITENYASNATFPTINNPILAKGQGIQLLEHKGRSFIANLTIAAKQLEQFQKATHMHYGFIYGRLFEGENYELNGTERLLILEEGQTVTIGQPVRGHLDLHGIKEHIKALPRGSKFVLRIADQTIAKGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7H0</accession>
    <name>A9B7H0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="9" type="ordered locus">Haur_0291</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MurJ/MviN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0291"/>
    <dbReference type="EnsemblBacteria" id="ABX02943">
        <property type="protein sequence ID" value="ABX02943"/>
        <property type="gene ID" value="Haur_0291"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0291"/>
    <dbReference type="eggNOG" id="COG0728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006797_5_2_0"/>
    <dbReference type="OMA" id="IFFVAFK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-294-MON"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="613" mass="66777" checksum="AB6A164E38455677" modified="2008-01-15" version="1">MSNESLSTTPAPAPSPLRKRSMSALLNSAIVMLGYLLSRVIGIVRQTVLSSYFGTNIVSDIYTTAFQIPDLLYLVIIGGALGTAFIPIFIEAYTKETHERAWQVANLVINAALTVLSVVSLAILLLADPLLRWLNPTYTPEQLGLAIYLVRLFMLSPLLLGLGGLAMATLNALDHFTLPALVPVIYNVAIIAGIVLIGPLLVRFGWVQHSISVVEHNGQPVSIEGAAWGVVLGALLYLVCQLPVLYRSGFRYRVLFNWRDAALRRIGLLMGPRVFGQAAMQINTIAIFSFAKLFGDGRATALSNALTLMLLPHGIFALSLATVMFPQLSRLDAAGDHEGFNQTTRNTLGTVLWAIIPAAAGLIMLATPIVQVLFQRGNFDSQSTLWVVQALMMYATALPAFGAAEILIRGFYARQETTIPVVIGVVTVALNIGLCWLLTQFSTSHIGLAGAFSITNNLELLLLLVMWRRRNGNLDATGQLRRSLLITLVSSLAMVLVLQAPVLALLLVGLLMLNYAWRRWGRQRWPQAGQAPIWLGLALATLAGLGLGWQLQLFDLATWLQIAPQAQSLWRLLGSLVFNGLLAIAVYFGCSSVLGASEAAVWQRRILGRLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J7</accession>
    <name>A9B7J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific DNA-methyltransferase (Adenine-specific)</fullName>
            <ecNumber evidence="4">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0318"/>
    <dbReference type="REBASE" id="16513">
        <property type="entry name" value="M.HauORF318P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02970">
        <property type="protein sequence ID" value="ABX02970"/>
        <property type="gene ID" value="Haur_0318"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0318"/>
    <dbReference type="eggNOG" id="COG2189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024927_10_4_0"/>
    <dbReference type="OMA" id="GTQHVIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-321-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002295">
        <property type="entry name" value="N4/N6-MTase_EcoPI_Mod-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00506">
        <property type="entry name" value="D21N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="31522" checksum="6E0A24463C77BE1E" modified="2008-01-15" version="1">MNSQQSNQLIQGEMLDVIGSIAPQSINLLYLDPPFAAGRVFADSAGAFDDRWQGGLTEYLAWLEQRLVAARRIVAEHGSLFLHLDRRAVHYAKVLLDQTWGFECFRNEIIWHYTGGGRARRSFSHKHDTILWYSKHPQHWTFNLQAMRQPYKASSGFAKAGIRSAAGKRYLPHPDGTPVDDVWDIPMLNPMAAERLGYPTQKPERLLERIILAASNSGDLVADLCCGSGTTAAVAQRLGRCWIAADQSADALALVRGRLRQQAAEWQETLIQPQPASFAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K8</accession>
    <name>A9B7K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0329"/>
    <dbReference type="EnsemblBacteria" id="ABX02981">
        <property type="protein sequence ID" value="ABX02981"/>
        <property type="gene ID" value="Haur_0329"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0329"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1719836_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-332-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17290" checksum="9364F456C72C96BE" modified="2008-01-15" version="1">MPNPLCISANELVCTDQSTTFEYVCHFENNREWWLPVTHTQHLSGEGVGAIYEEHAKVAGIPMKMQLKVYHYNPPQQIKFTITSALMLSDMDYRFLVESAGTRIIISTAINFKWFLRPFAPLMRSALIKEASQHLGVLKSVLAQKFSQASNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M6</accession>
    <name>A9B7M6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0348"/>
    <dbReference type="EnsemblBacteria" id="ABX02999">
        <property type="protein sequence ID" value="ABX02999"/>
        <property type="gene ID" value="Haur_0348"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0348"/>
    <dbReference type="HOGENOM" id="CLU_1956588_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-351-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012640">
        <property type="entry name" value="Membr_lipoprot_lipid_attach_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08139">
        <property type="entry name" value="LPAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005661085" evidence="2">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="13968" checksum="7DB19666BC0A383A" modified="2008-01-15" version="1">MRRWFLALCLLVVLAGCSGSSIATQVSDTVQQLSETSVQDLVDRLSGIEEAVRNNDWEQTRALFSTVENGWNALRVPVEAAFPEIASNIQAQIDQLSQALSVELPSSEDVRAGLSNLRDQLVALLQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P4</accession>
    <name>A9B7P4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1779"/>
    <dbReference type="EnsemblBacteria" id="ABX04422">
        <property type="protein sequence ID" value="ABX04422"/>
        <property type="gene ID" value="Haur_1779"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1779"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_270720_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1807-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="397"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1216" mass="132472" checksum="B9998ECD298D88E5" modified="2008-01-15" version="1">MQSLLNELPGKGQLTSLLDGKFTPSAVGADGMREINAGAIKDDLAAATPDGTSPAVSLPVMPQGLTKEGFTGRINAPLDQLGGVNRNALIGDVTSKPLPINLPAPTFDVNGTMGKITNAVIPVQVDTPTTTPDLPWLDVDSFTAPLRKLADAGASTPMRILGMLLKIVESFKNTLTDPAKMTELTTEALAEIYVVQLRTLRHNLPLHSLTATNSLLSSGYLKSYQQALDALEKSQDIDAFQKLGRSTLLSGLSQIQQSDKTLQRMLAKDVAQLQQALTQVLDFGAADDVFLQAYFDQLTARTGQVLGAITSPIKELTDMANDIVKYLEAAAKKAEEAARNVSTAIETNIQSVSGVLNGLQTQITNVTAEIEAFLSQVDVGPVVRQIKDGCNRISSVIEQFFVRIEELKLKLDAAVKNVQDNVDAKLTQTFNTLEQQIRQLLGKISEVLNRPDVQDALNKARQGIEDFKTKIGDASLKPVFDLVIEQTTKLEGNVRAIDVASMGTPQKTALKVGAKVIEAVKVDEIVKPELLDAFRQIREPLQELVNLLKNQVLVIERMIDEFNPGTIATDAILNSAPYQLVIKTLEEFKPSELLAPLKDANAELAKLVAKLDPEIILNELQRLYDQLYSLVETLSPESLNQLINKAINAASKELTNIRDYEIDSLLSTIKSAVSLEKLLAKTGLQDLADAEFWTMLKKVLGGDYLDEVSAAMDSIEVSLRANAATLTFPSVADEIAKTREAFQLELGVTSTNLDAAATTLSQTIAAAAAEIEGLQVRRRTLMQTYDLSTGTGLMLRDLDLAPLTALSTTLGQVTGSTKTALNSCIGVYKPVIKAEESRIIALNESVLQNVVAAMFKRQFGDPVRKFVTDVKVQLQPFKDAITAIQKILTTVTKLPAQIDAAVANVLDTLGLSIKQVITDILALIETIRTSLISVIKTTYETVKRSVEAFSPMWLLNSVSASDFAGQGLMTLALRIRNPSGDRLAALVQTKLTAAALELLQNQAAGSLSEVNATNVLQAINDTLRDATISTQATVDLVTQQLSSAIGLIEAKPAETRSASEMQQLYRYLALKGQLGRAWYELSRTPTNQNRLIRLNRVLFEASYPSDLGMSLQSLHPFIVEEIAHLYPEETVKRLDVIYKIIIDKIKGLPDQLIRRPLDDEFNKIKQLLHKTFDIEGLFNVIDIKLAGLDGDLEKGLDRLSDAYGQLLNTLDERLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7V8</accession>
    <name>A9B7V8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1843"/>
    <dbReference type="EnsemblBacteria" id="ABX04486">
        <property type="protein sequence ID" value="ABX04486"/>
        <property type="gene ID" value="Haur_1843"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1843"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055111_0_0_0"/>
    <dbReference type="OMA" id="GLHIERW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1872-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="377" mass="41981" checksum="B1C408E30AE2A103" modified="2008-01-15" version="1">MIVIGNPHDRRVALWQAALARQGQPPACVISYYDLLAGQHDLAELIKSSELVRIESPGKDEQLYRELVRFAAELTPEPEFEHWPIDANLPQERGRLWGSRQWYRGYTRLLSQLGQQLASLNVRLLQHPADISVMFDKVACHARLAQADVLVPRSLPAIGSFEQLQTALQTHGWQRVFIKLAHGSSAAGVVAYRTNGRQMQAITTVELVETSAGLQLYNSRNLRTYTHLREIQPLIDALAQQRVHVEEWVPKARLAGKVYDLRMLVIAGKAQHTVVRTSTSPITNLHLLNPRGDLAAVQAQLGAEFWQIVRQQAEAASACFERSLYAGVDLLIANSLQHCLVGEVNAFGDLLPNVLVDGLDSYEAEIVGAGSWWSGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B810</accession>
    <name>A9B810_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative [LysW]-L-2-aminoadipate 6-phosphate reductase</fullName>
            <ecNumber evidence="1">1.2.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysY</name>
        <name evidence="3" type="ordered locus">Haur_3307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + NADP(+) + phosphate = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:41948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9712"/>
            <dbReference type="Rhea" id="RHEA-COMP:9714"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78499"/>
            <dbReference type="ChEBI" id="CHEBI:78501"/>
            <dbReference type="EC" id="1.2.1.103"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.103" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3307"/>
    <dbReference type="EnsemblBacteria" id="ABX05943">
        <property type="protein sequence ID" value="ABX05943"/>
        <property type="gene ID" value="Haur_3307"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3307"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_1_0"/>
    <dbReference type="OMA" id="FSWRNNN"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043870">
        <property type="term" value="F:N-acetyl-gamma-aminoadipyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02083">
        <property type="entry name" value="LysY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037535">
        <property type="entry name" value="LysY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="37435" checksum="501A143D119075F9" modified="2008-01-15" version="1">MLSVSIVGGSGYVGGELLRLLLGHPHVEVRQVTSERLAGQYVYSTHPNLRGRTDLRYSPQSTLEPCDVLILALPHGSAAKKIEHYAGLGQALIDCSADFRLRDPEAYSRWYGEPHPAPQWLERFVYGLPELYREQIRATRYISGVGCNATAINLALLPLVKAGLIDQTKPVVAEVKVGSSEAGAVANDGSHHAERSGVVRSFAPVGHRHTAEIMQAHGLENVHISITSVEMVRGALATCHVFTQGSVNERDLWRAYRAAATEQPFLRIVHDRSGLHRHPEPKILAGSNYADIGWALDEATGRVVALCALDNLTKGAAGTAIQCLNLMHGFDERLGLEFTGLHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B822</accession>
    <name>A9B822_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 type 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3319"/>
    <dbReference type="EnsemblBacteria" id="ABX05955">
        <property type="protein sequence ID" value="ABX05955"/>
        <property type="gene ID" value="Haur_3319"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3319"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068006_0_0_0"/>
    <dbReference type="OMA" id="PNSNVRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3356-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="249"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="34270" checksum="89F8D95940F3329C" modified="2008-01-15" version="1">MTDQLPPTQPRQPQPSQARPEAAPPQVADAQLRQLVVALDNVNDPNHERAEDDLIRLGAQAVPLLIDALDPRYPWLRAYRAAEALGQIGDGRASRPLSQALNHPNSNVRWAAVRALGKVGDGRALLALRRTARDDRSRTSWGEPVAASAAATLREMQRTSTILRLSDPIRIALLVAVAFFALFWANDRITTVRGAINESNHVVWGTAVTPILPTATPVSEDLSSEDDPEEDLVEETPTVDPAATPTLAPATATVVAPTANVRPAPNTNNDPIAQLKAGDSVQVLGQSGDWYEIQLPDGTGRGWVASSVLGPPSGPVPTVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B830</accession>
    <name>A9B830_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type Na+ efflux pump permease component-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3327"/>
    <dbReference type="EnsemblBacteria" id="ABX05963">
        <property type="protein sequence ID" value="ABX05963"/>
        <property type="gene ID" value="Haur_3327"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3327"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046841_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3364-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="411" mass="44894" checksum="CC0890B4B03B95C9" modified="2008-01-15" version="1">MAKMWFVARRDLMYHLRKKDFYWSTLGVPLLIGAIYLFAQVFGGDPSGQATANLFLPSTDRAHSIGVVDQSAVLKQHFEVISPTTLLQFDDRNVAEQALRQATIETLFIIPADYHQSGIVTRTTRTASVFDQADTNALRSLLAANQLRSPHIDFVPLLFEPISLSKAEAIGQNVRVAGNLSQNFAGSMVPIGFAMAIYISIFMGASLLMQGILEEKENRTLEVLLTSISPRQLLTGKMLGLGIVAFIQLGFWAALALGVLRGQAIREALNQVQIDSVTWMLLGIFFLLGYLFYASLTAGIGAISPSMRELSQLIILVSVPAMIPLMFITSLLSKPNGALALILSIIPFTAPSTMMLRSVMTVVPPWQIGLSIGLLALAVVATLSVTARLFRATILLRGSKFSLRGLWQALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B865</accession>
    <name>A9B865_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="17">BCAT</shortName>
            <ecNumber evidence="17">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ilvE</name>
        <name evidence="18" type="ordered locus">Haur_3362</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 17">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 17">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 17">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 17">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 17">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 15">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="17"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3362"/>
    <dbReference type="EnsemblBacteria" id="ABX05998">
        <property type="protein sequence ID" value="ABX05998"/>
        <property type="gene ID" value="Haur_3362"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3362"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_3_1_0"/>
    <dbReference type="OMA" id="WRGSEMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3399-MON"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17 18" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 17 18" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABX05998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="35009" checksum="C0787603C92D2D1B" modified="2008-01-15" version="1">MSTNRFAFFKGEIVPIADAKVSVMNHALNYGTGCFEGIRAYWNEADEQLYVFHLQAHYERLLRSCKVLQIRLPYSAEQLVETTLELLRREEFRSDVYIRPLAYKSFEGIGVRLHDISDDFTIWAIPFGKYIEKEAGLKVGISSWRRIDDNAIPARLKATGSYVNSALVKSEAMQNGFDEGIVLTQDGHVCEGSAENIYVVRNGVLYTPGITDNILEGITRHVIKQLATEELGLQVVERSIDRTELYAADEIFFCGTGVEVTPVVEVDHRAVGNGQIGPIFSQICSLYYAVTHGQDPKRREWCSPVYNSVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B1</accession>
    <name>A9B8B1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="4" type="ordered locus">Haur_3828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3828"/>
    <dbReference type="MEROPS" id="S14.001"/>
    <dbReference type="EnsemblBacteria" id="ABX06464">
        <property type="protein sequence ID" value="ABX06464"/>
        <property type="gene ID" value="Haur_3828"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3828"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_0"/>
    <dbReference type="OMA" id="RDYWMKA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="24039" checksum="F68B4FA36AB7E100" modified="2008-01-15" version="1">MSWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIANVLVAQLLFLQHDDPDRDISIYINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMATPVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIKELLRLQNIVRGLLAKDTGQPIERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W2</accession>
    <name>A9B8W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07776">
        <property type="protein sequence ID" value="ABX07776"/>
        <property type="gene ID" value="Haur_5148"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5148"/>
    <dbReference type="HOGENOM" id="CLU_703523_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5210-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="42465" checksum="D838E73642E504F0" modified="2008-01-15" version="1">MEQISESDPQFVHFQHGCPTLSREEQVVLFHALRNQGMTFASNGTVAITNSVIHGPVAGINFGTMQSIIQMLPEPIDPLPAALAALAAIPLDHVPQPRSDLPHASRLPFEASPHFVGREDELKQLAAAIGTAQPAVVMPAVATGLGGIGKTSLVTEFAYRYGVYFHGGVFWLNCADPDQVASQIAGCALALGIDLTGMALDEQVQRVLNAWKSPMPRLLIFDNCEDRAILDQWKPTVGGCRVLITARSDQWPTLTQIRLGLLSPTESRSLLQRLCARLTDAEADAIAEDLGHLPLALHLAGSYLNTYSHHTVEQYRKDLTIAHRSLKGRGALPSPTRHELDVEATFMFSFKQLDANDALDALALGMLDGAAWCAPGIPIPRELVLAFVPDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B983</accession>
    <name>A9B983_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07897">
        <property type="protein sequence ID" value="ABX07897"/>
        <property type="gene ID" value="Haur_5270"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5270"/>
    <dbReference type="HOGENOM" id="CLU_1487127_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5332-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025850">
        <property type="entry name" value="SUKH-3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14433">
        <property type="entry name" value="SUKH-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20034" checksum="403FC3EA934401DA" modified="2008-01-15" version="1">MTLNINLLTDQTIFLLTAAGWSPERTYDPTTTIIQPLTTIGWPIFPEAQRIFTALGMLNLNLQHLPPIPPDPRTTTPDPIALRDHLWYADIRIDFDPAEAFAIDDEDFIVYWSSHPLVQLHGGGICPIGSYHPWDTLLVCGDGLIVHGSPEFMNPAPGLVVLGSNIETALNQLAHQAVFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUA3</accession>
    <name>A9AUA3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0371"/>
    <dbReference type="EnsemblBacteria" id="ABX03022">
        <property type="protein sequence ID" value="ABX03022"/>
        <property type="gene ID" value="Haur_0371"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0371"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-374-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="252" mass="27163" checksum="7E2D0A515B5B3E5A" modified="2008-01-15" version="1">MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSDHEAVAALAAQITQRYVQLDLLIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLLPKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAETTIKIVRVYPPATKTAMTTAMAQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQQLIKLWGGSTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUA5</accession>
    <name>A9AUA5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.173</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.173" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0373"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03024">
        <property type="protein sequence ID" value="ABX03024"/>
        <property type="gene ID" value="Haur_0373"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0373"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_8_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-376-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102203">
        <property type="term" value="F:brassicasterol glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102205">
        <property type="term" value="F:cholesterol alpha-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102202">
        <property type="term" value="F:soladodine glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="417" mass="45257" checksum="B45F6714473167CB" modified="2008-01-15" version="1">MNYCILALGSRGDVQPFIALALGLQTEGHQVVIAAAHDYRSLVESYGCRFAPLVGSISALLNPEQMAAGLAAGRSAIIKQFLQQTPPIIRQLIADALAACQTADCLIVSSLGMWPALHLAEHLHIPVVLVHLHPYAASSQTAHHFAPQLAWASYRRMSYRVAEQLQWQVLRMAFNQARQQILQRPSLSIGQLWQRSRNFQPPTLYAYSALVAPPPATWFDDGAITGYWSLPPAADWQAPTALQQFLAAGPAPITISFGSMLHGQKRGNQLSQLLITASQKAKVRMIINQGWGDLAQGKLPANCLAINGLAYAWLFERVAAVVHHGGAGVTATALGAGKPALVTPFLGDQYFWGQRVYDLKAGPAPVPANQLQVAQLATLLCSLIERDDYQAAAQQLATQLAQEQGVTKAIAWLKQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB7</accession>
    <name>A9AUB7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0385"/>
    <dbReference type="EnsemblBacteria" id="ABX03036">
        <property type="protein sequence ID" value="ABX03036"/>
        <property type="gene ID" value="Haur_0385"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0385"/>
    <dbReference type="HOGENOM" id="CLU_2699672_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-388-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8659" checksum="8ECED7581471F6A4" modified="2008-01-15" version="1">MPQYKNRMYRKEWLSERRKLARALEGLEQNWDLEAEGIVLPTDDDGATLTVEQLRERIADLDGKLERYPNPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE4</accession>
    <name>A9AUE4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0412"/>
    <dbReference type="EnsemblBacteria" id="ABX03063">
        <property type="protein sequence ID" value="ABX03063"/>
        <property type="gene ID" value="Haur_0412"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0412"/>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026231_3_1_0"/>
    <dbReference type="OMA" id="PNCESHQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-415-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="73"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="396" mass="42789" checksum="8B89FD36508BAC3B" modified="2008-01-15" version="1">MPANLQSTFDLAQFEALLASRNEPSWLTSRRREAWEAFETAEQPDWRRTNLKGFNIADYTLAEAEVSVDFAGAEGVTILPLAEAIQSHAELVQRVLGSAVQTSRDPFSALNNALVNGGIFIHVAKDVAVEELVRIRYHLSNAGTVVAPRTLIVTERHSSINVIEEISSADFAGSAVVLTGAEIEVGDGGQVGFSSVQTLNSNVYLLGSQQIRINRDAQAEWLNVVVGSAVQHVTLEANLSGNGSSVNWNGLLYGNGKQNLLVAPKLNHIGLNTEGQINFKTVVDDEAYAVFDGMVKIPATGQGTNSDLRENALHLSKNSRSDSIPGLEIDANEVKAGHGSTSGQIDEEQLFYLQSRGLPFAEAKRTIVLGFVGEIIDMIPDEAVRERVETIVAEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF1</accession>
    <name>A9AUF1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0419"/>
    <dbReference type="EnsemblBacteria" id="ABX03070">
        <property type="protein sequence ID" value="ABX03070"/>
        <property type="gene ID" value="Haur_0419"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0419"/>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006338_0_0_0"/>
    <dbReference type="OMA" id="FNIERFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-425-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734333" evidence="1">
        <location>
            <begin position="25"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="2">
        <location>
            <begin position="26"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1052" mass="108601" checksum="33831E95CB2B4D8F" modified="2008-01-15" version="1">MQFKGLRLLTALTMLFTLIGTSLSATYTTPTSAVSTSLVISQFQTAGGTADDEFIEIHNISANPVDLNGHRVVYRAAAGVTDVSIASWTSSVVIPAGGFYLLGRANSYDGTVTADTTFGSGISGTGGGFAIRNGDLNTGTIIDSVGFGSATNAFVEGTVVAAPSANNSAQRNNSSCTDTDNNAADFSLLTPSAPRNSSSPVATCGGLPTDNPPTVASTVPANNANNVALNANVTLTFSEPVTTTGTWYTISCTSGARTASVTGGPTSYVLDPSSDFAASDACTVTVVASQVTDRDGSVDAMAQDYSFNFNVSSGVACSGGTVTPIGQVQGTGETSPANGTVVTVQGTVVADFEGAQPALRGFYLQDAGDSNAATSDGIFVFNGGADQVALGQVVRVTGTAGENQGQTQLSGSLTVELCGTTNTVTPTQVTLPFASTTDAERFEGMLVQFNQKLVVSEHYLLARFGQVTLSLNERLAQPTNVVSPGAPALALQAQNNLHKIILDDPFNNQNADPILFGRGGTGLSAANTLRASDSITGLQGVMTYTWGGNSASPNSYRVRVTQSPNFVAENQRPTSLELDGSLRVAGINVLNYFNTFGNGNCTGGVGGAATDCRGAENTTEFQRQKDKTIAAIIMTQADVIGLMEIENDGFGSNSAIQDLVNGLNAATAPGTYALVDVDTRTGQTNPLGTDAIKVALLYKPGKVSLAGTTAVLNTGAFGDFTTSSGTTGRNRPALTQSFTETSSGETFTVVVNHLKSKGSACTDNVSPVPSDPDLGDGQGNCNLTRKTAAQELVAWLNTDPTNVDDSDYLIIGDLNSYAMEDPITAIRNAGYVNIPKTLLGDEAYSYIFDGQTGSLDHALASTSLFSQVADVQELHINADEPIALDYNTNFKSAGQIVSLYNNDAYRASDHDPIVVGLALGAAPTANFSTSTKTVSSTSVEQGEVFTYTLTIRNTGAAEGSFSLSDLINSNLEIVGVTGGLTVNDQTASVNSSLAPSSNKTYTIAVRSVGNFVGSVGNTAVLNSNINLTADSVTVNATTTPSFTVYMPLVTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUG0</accession>
    <name>A9AUG0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0428"/>
    <dbReference type="EnsemblBacteria" id="ABX03079">
        <property type="protein sequence ID" value="ABX03079"/>
        <property type="gene ID" value="Haur_0428"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0428"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066398_0_0_0"/>
    <dbReference type="OMA" id="GIWASAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-434-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="38983" checksum="8A32BCBE9E0FF753" modified="2008-01-15" version="1">MSNRAVSRRWSLQPNPIVVKELRSRMRGGRAFILLTGFLLGLGLVGYALFLRATSGQAAGMPIFSAQIGQTLFAGLAFMLLFLVILIAPAVTVGAISSERERLTYEMLIATNLPSHRLLWGKLISALSYIALLLLAAIPLGSIVFLFGGITLRHVLQAAAIIVLSAITSAMLGIWASAMTGKTGRAAVVSYVIIGLVLGGFLAGAEIWTNRSTEPVPTGLLAPNPISALASSIGTLSGPSNGGMITTMRAFEAVPMAAGGGWWPGMNSFSGGLNFPGWQTFSIGIYPATDQFGPDGMPIIAEPRSVWRTTLIILIMTCLVFFWMALHAVKPRRRWWPTWGDLAMLSVTSLSLLGLGYWIGWWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS4</accession>
    <name>A9AUS4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N6_Mtase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1958"/>
    <dbReference type="REBASE" id="16529">
        <property type="entry name" value="HauORF1958P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04601">
        <property type="protein sequence ID" value="ABX04601"/>
        <property type="gene ID" value="Haur_1958"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1958"/>
    <dbReference type="eggNOG" id="COG1002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002881_0_0_0"/>
    <dbReference type="OMA" id="VDSRMKF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1987-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="457"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1333" mass="151391" checksum="3F4B838EB2509EA4" modified="2008-01-15" version="1">MKYTAIITEGGLLPADMLQAIAEGEQGSLAGQRPADFGLPANRRMSDDIAAAWGQVRAQWQIFQAAIERRPQDSHTTLTRRYWVEPFLQLIGYEPTSTKSARRVDNRTYAISHSADEHDDSPPIHIEGIKTDIDRRPESGRPRISPHALMQEYLNSTEHTWGIVTNGRRLRLLRDSSQTTRPSFVEFDLESLVTGQLFNEFALLYRILHRTRLPITSADTAQSLLEQYHQQAREAGGRVREGLREGVERALKLLGQGLLRHPRNSDLRQRFATNQLTPLEYYRQLLKLVYRLLFLMVAEDRGLIEAETASDKLSELAQRGTPSERLKLYYEHYSVGRLRRLAEVRGAGRGPYDDIWMALQQTFRIFEGTDLKANRLGIAALDGDLFGEGAIGALETAHLRNADVLAALRALSIYADPQSRALRRVNYAALDVEELGSVYESLLDYRPVVAGTSFDLVAGTERKTTGSYYTRPELVQELIKSALEPIIAERLRDKNPEQALLSITVCDPACGSGHFLLAAARRIGRELARVRSGEDQPTPDQFRHAVRDVITHCIYGVDFNPLAVDLCKLALWIEGHCAGMPLSFIDYHIRWGNSLVGATEELVNQGIPDDAFKPVTGDDKTIASNLRKRNKREREDIASGQITMNLAPSQLDHATLGRATRQLEALPDDSVAAVRAKAARYARMREQERPNWTRYNLWTAAFFQPITKDTLPLIPTSATLHAFDTARQSVSAGLLAWVDGLADQPEMRFFHWELEFPHICGEGSPRGFDVILGNPPWERIKLQEQEHWVDVAEIREAANKAAREKLLKAWASSSEPSKQQRYAKFEHAKYIAEAASRFIRVSQRYPLTAVGDVNTYALFSELDRDLINRKGRAGIIVPTGIATDDTTKAFFGDLIKKQSLERLIGFENEAFIFPEVHNAFKFCALTMVGNDISSETPDFIFLCRYFSDIEQDARHFNMTSDEFALINPNTLNCPIFRTKTDAQLTKKIYRIAPILDNQKTKRNPWNISFGTMFHMANDSGLFKNESSRDRMPLYEAKMIWQFDHRFASLIGKENAGNRLSRKYEGWYGADYGNPEDLPIPTYWIDRESIEDRIPSKHQNKWLLVFRDITSSVVERTAIFSLIPRVAVGHTAPLIFLTDINSSLFSCFLSIVNSLCFDYIVRQKIGGTHLTFGYVKQLPVLPPERFDAAQLAFIVPRVLELVYTAWDLQPFAADVWAELDETGRQALLAQNAECNRDAPPEWFSPRDGFALPPFRWSDERRAVLRAELDARIARLYGLSRDELRYILDPAEVYGPDFPGETFRVLKEKELKQYGEYRTRRLVLEAWDGEDALTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS9</accession>
    <name>A9AUS9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1963</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1963"/>
    <dbReference type="EnsemblBacteria" id="ABX04606">
        <property type="protein sequence ID" value="ABX04606"/>
        <property type="gene ID" value="Haur_1963"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1963"/>
    <dbReference type="eggNOG" id="COG0490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_9_1_0"/>
    <dbReference type="OMA" id="IRPFHDV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1992-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="6">
        <location>
            <begin position="416"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="579"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="661"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="684" mass="72464" checksum="0E7E1CDB09A21B20" modified="2008-01-15" version="1">MPHDISLITNISVALVVAFAGGLLARRLGLPTIVGYLLAGMLIGPFTPGFVGDIGDISQLAEIGVIFLMFGVGLHFSLKDLWSVRKVAIPGAALQMLLATGLGFGLTRLWGWTTAAGLVVGLAISIASTVVLLRGLMDAGQLNTPAGQTAVGWLVLEDLATVLILVLLPALFGSEGGNPWVTGGLALLKTTAFVLIILFVGGRFLPWLLTSIAHSRSRELFILAAVAVALGTAFAATAAFGVSLALGAFLAGVVLGESEISHQVGDEVLPFREIFAVIFFVSVGMLVNPQYLWDHIGQVVALTALIVIGKAIFTLFLGLILPSTGRTMIVVAAGLSQIGEFSFIVGQAGVGLGVLTQDQYSLVLAGAMFSIMLNPVMFWSIPHVETWLKRYPKLWARFERHATTEPQPTTLPQAEHVVVVGYGRVGEHIGTVLNRLQIPFLVVEADNHRADDFMTKHIPTLIGDAANSDVLTHAKLEQAKALVVTLPNEAASELVVAAARDLAPNLPIIARAATNSGVQRLADLGAQDVIHPELEGGLEIIRHTLLRLGYPATQVQGYTDAVRRDQYHTDITPTEHLILEQLIQSVRGFEIAWRGIAASSTMIGQSLAALNFRAQTGASVIAVIRDQQLISNPESQLTLAPGDLLGLIGDESQINAADSLISRSQASEQSTNQPSAATFAPSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW2</accession>
    <name>A9AUW2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3916"/>
    <dbReference type="EnsemblBacteria" id="ABX06550">
        <property type="protein sequence ID" value="ABX06550"/>
        <property type="gene ID" value="Haur_3916"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3916"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1271174_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3958-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23468" checksum="17831C1327A89E5F" modified="2008-01-15" version="1">MTVIALAGATGYTGQRIISQAANNSEWQVRALVRQSATSKTHFPLGQAFAICDFADQASVEAALEGCEAVFQTIGTTQAQFNADVSYETVDYGTTIALIKAAQAQGVKRFVLLSSAGAGLPLGSYLRWKAKTEKAVRESGLDWTILRPAAIVGPSRRAIQLASMPFALLSKLPLIGRLGAIMRPVDVNDLALSFFKCLADETTIGKTLEGRSFWRLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV35</accession>
    <name>A9AV35_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03113">
        <property type="protein sequence ID" value="ABX03113"/>
        <property type="gene ID" value="Haur_0462"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0462"/>
    <dbReference type="eggNOG" id="ENOG502ZCFH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775383_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-468-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="37688" checksum="365992CD7FFE8F8E" modified="2008-01-15" version="1">MNFREYRIAAPNVRSLCWHDQSLVDWVAGGTRYQLDGPIKRSSTVYPFGFDAAVQSASGEVVVIYQRLGTKGLVLNNGQIVREINRSYYYADSYEYPIAILQHADLNEVLVHCPEKYNQLELEDVVTNRRLNEAERKPVEIFHSRLSVSPKGKWLVSAGWQWQPTHTVAIYNVDEIWAQPQILDTEGFCPSIQVDISSVSFLDEQTLLIITDEFANLSADLVDTLVQRRGAHSIGYYDLLNRQFRATVEAEEIVGTAMALSERYVVGFYDHPKLFDCTTGKVVQRWPDLATGRQTHSMIGRLDQSIPPIAFDQANQRFAVADAKGITVIELSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE7</accession>
    <name>A9AVE7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1995"/>
    <dbReference type="EnsemblBacteria" id="ABX04638">
        <property type="protein sequence ID" value="ABX04638"/>
        <property type="gene ID" value="Haur_1995"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1995"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2024-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="949"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1019" mass="114373" checksum="34D686F79812BE9C" modified="2008-01-15" version="1">MVFRAISHRTTPICDTEWLEYTINGRIQRVAVESRAWYEWLHAPAHTAFAFMCSSGTFTARREARRARAYWYAYRKKAGKIAKVYLGSAEQLTLERLIRAAATLAKQPSVPVPTPLLHTKLSIPAVRSRFVSRRSIFTVFNQMLPLTLVSASAGFGKTTLIAEWARTQPYPLAWLTLDSNDNEPSRFWGYSLTALHMVAPLLTTEALALLHAPQAIDLSFVLTNLINNLMLLNQPLTLVLDDYHTINNQAIHNQLTWLLDHAPQAFRLVLISRTEPPMPLARWQAAGRLNTILVDELRFNNSDIHRFFHTTMQLDLAADVLASLAARTEGWIAGLQLAALSLQGQPELTMSEGLDSSVSNQRALFDYFSHEVLQQQPSAIQQFLLQTAILDQLCEPLCAAVTDHGATAGMLDYLERSHLFVVALDRKHHWYRYHQLFRESLLHHAKQQWGAAGIAQLHKRASCWFEQAGYPAEAINHALAAADFERAGRLIAKIGFRMLWRGEHTILKGWLHALPATIIEHNAYLCLWSAWLLVEQNQLEASGYYLSLIDELLSHTMSDEAAETRAIDGHRKALQASIARRRGDMPTTLALTHQALNALPRDSALLRSMITRNLCAGYIISGDTVAAEAALHQALCEQELLEASIASDHHHPSERQHAHTIRLLLWIETTSLRWLQGQFHAAADLYRQTLHLAREQHQHAVSAIACVNLGQILRQWNNLAEAREYLQQGIGYSLNVGADVTRRNGLIELARIQQAHGEPAQALATMAQAVALAQTLPSPRGLLWATTWQARLQLAQGDLAAATRWAQEYQRLANPFPQFNIYDAEDLTLARILIAQGQHQQASALLEQLLPAYQAAGRLPSVIEVYLLQALNLAAQQDWSVAGRVLIQALRLAEPENYLRLFVDEGPALSNLLVQIEPQVQATLRQYVQRLLVVCELPRSTTPEQLSPIYRLIEPLSERELTVIRLLAAGFSNQEIAQQLVVTLNTIKTHLKNIYSKLAVTSRTQAIARARRLNLIANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL9</accession>
    <name>A9AVL9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalamin B12-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3987"/>
    <dbReference type="EnsemblBacteria" id="ABX06619">
        <property type="protein sequence ID" value="ABX06619"/>
        <property type="gene ID" value="Haur_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3987"/>
    <dbReference type="eggNOG" id="COG2185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128233_0_0_0"/>
    <dbReference type="OMA" id="VYTGLHQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4029-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="14592" checksum="89572D47AAB3A4A5" modified="2008-01-15" version="1">MERPIRVLVAKPGLDGHDRGAKVIARALRDAGMEVIYTGLQQTPQMIVEAALQEDVDCIGLSILSGAHMTLLPKITTMLRENDGADILVVAGGIISDEDAAILRNDHGIAGIFGPGSSTHAIIDFIREHVERSSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ0</accession>
    <name>A9AVQ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4018"/>
    <dbReference type="EnsemblBacteria" id="ABX06650">
        <property type="protein sequence ID" value="ABX06650"/>
        <property type="gene ID" value="Haur_4018"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4018"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_8_6_0"/>
    <dbReference type="OMA" id="RIHPHGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4060-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735252" evidence="1">
        <location>
            <begin position="27"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="83"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="553" mass="60762" checksum="6A321A9075E47114" modified="2008-01-15" version="1">MMRILTLGLLAVLLTACSLGSTPAPTNEPTTPPIQVPQGGTLTIRTAQDIAALHPWKPTCHEEAQLLGLLYRGLTKLDQSLAPQPDVATSWQSDSIGQTLTMTLRSDIRWHDDTTLTAADAAWTISAMQSISPTTPLLTDLQGLVRKVTAPDDTTLVISLREPYAPLLSALSMPILPKHVFEQLSPVELDQLNLLTQPIGSGPFMFEQRTAGSAISLIRNSNYIDGVPYLDRVAFVVAPDPQVARQAVRDGDLLAAELPWAQSQGLGPTVGIGSYPENGFYYLAFNMRDGRIFSDQRVRQALALSLDLNTIVETAGPAAQAILSDHLPGTWVAPTGELPKRNLDQARELLDQAGWVLPEGATIRASNGITLSMALFVRGDDQRRIEVAERIAAATRPVGFNIVVTPADFESVIRSKLVTPFDFDLALMSWGNSRVGGSPSYTAYDPDNFSLFHSSQIYQGVADGRPGLRNYGAFQNTSFDNLSTAARALYATERRRELYQQTNTIIQTEYPYVFLWADRIPVALAKQVRSTQGEIRLDTANWLYDVQHWYLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ8</accession>
    <name>A9AVQ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4026"/>
    <dbReference type="EnsemblBacteria" id="ABX06658">
        <property type="protein sequence ID" value="ABX06658"/>
        <property type="gene ID" value="Haur_4026"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4026"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_584873_0_0_0"/>
    <dbReference type="OMA" id="PETIMIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4068-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="255"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="5">
        <location>
            <begin position="326"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="539" mass="57908" checksum="90E2A8C0B95FD851" modified="2008-01-15" version="1">MTEKRTPRRRVQRAQTQNNAEVILLPAPNHTTTAFRQKSDTGRIESLNRGGRSAQRRRKQEQRAASIARSSLAQIAGTPTRAPQAISEPKQPRRSFKAAAQSVRQRLQLQRRLVAHSVILLAACVVAWGRGFPLNPVSDNATNQAIPEVLAAAQLVDEVEAGNFQRVVIPISATQPQSVGGGEHEVVVDVGPALIKPAPERGPAFVATHLVANEETIADIAAKYTITPESLIAANNLTGPVAIGETLRIPRVSGVPHTVSEGETITDIAERYSVGADVIMTFPPNGLDQGQALIAGREIFVPGASLAGVQNVSVRGAIDSINQKSQAAAIVLADRTNLREGPGTAYEKIVKVNAGERLQLIAKHEVWVKIRQSDGEVAWVAREVVSIPEEVWSALEETDNFPPPPPPPPVWVWPTYGDLTSGFGYRNFSVGRFHNGIDIANRKGTPISAARRGTVIEAGWCSGYGYCVKISHGSGMVTEYGHMMSNPVVSEGQEVEAGQLIGYMGSTYDRAGGGYSTGVHLHFTIKVDGTAVNPLKYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW2</accession>
    <name>A9AVW2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0552"/>
    <dbReference type="EnsemblBacteria" id="ABX03200">
        <property type="protein sequence ID" value="ABX03200"/>
        <property type="gene ID" value="Haur_0552"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0552"/>
    <dbReference type="HOGENOM" id="CLU_1376512_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-561-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="21141" checksum="D7C79D08C3223DC2" modified="2008-01-15" version="1">MPTDVAAVTMSNAKLLYAPVGTTLPADSLAVGAAWPVGWVQYGLTSAPLVVAYSYETKAPEIQEALGAVKRKKVSEELTAETTMAQLDFAGLPSTWGGTNTVVASGVGQVGKETFKIGGAAQLPIRMWGFEAEQEDEEGNVFPVRGFIWKATSEEGGELEFSKEDWTGIPLKLSALEDLSKTKGERLFQLVRVVEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY6</accession>
    <name>A9AVY6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated RAMP protein, Cmr4 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0576"/>
    <dbReference type="EnsemblBacteria" id="ABX03224">
        <property type="protein sequence ID" value="ABX03224"/>
        <property type="gene ID" value="Haur_0576"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0576"/>
    <dbReference type="eggNOG" id="COG1336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047795_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-585-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013410">
        <property type="entry name" value="CRISPR-assoc_RAMP_Cmr4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36700">
        <property type="entry name" value="PTHR36700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02580">
        <property type="entry name" value="cas_RAMP_Cmr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="278" mass="30524" checksum="62DBFAB9DA0D9CE7" modified="2008-01-15" version="1">MQTHVIFVHALSPIHAGTGQSVDVIDLPIAREKATNLPYIPGSSIKGVIRDVSPASESLKKQLFGDVEQAGDAIFADQRLLLLPIRSLYGTFAWVTSPYVLSRFAREAQTSNLWLPEIKRSELALISQNSVLSYQQKVYLEDLDLEATPGADAWAGWLAKQLFPDKPDWQTILQERLCIVPDEIFNFLVTTATEITARIRLDDNTKVVTKGGLWYEEALPAETILAGIVAINDQKRSANRDQVITAIIEVANQGIIQLGGNATVGCGLCQLTIAQGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW45</accession>
    <name>A9AW45_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0635"/>
    <dbReference type="EnsemblBacteria" id="ABX03283">
        <property type="protein sequence ID" value="ABX03283"/>
        <property type="gene ID" value="Haur_0635"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0635"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2141453_0_0_0"/>
    <dbReference type="OMA" id="EQHPPHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-644-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12506" checksum="BCF738B53AC5B1D0" modified="2008-01-15" version="1">MEMDHVAVVVNNIAESTAWYVAQCGAQVLYADDTWAFLRIGQGKLALVMAYQHPPHVAVRVDETQLNALAIQHNQPIDRHRDGTKGFYLRDPNGNVLEVICYPPAETVYNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW78</accession>
    <name>A9AW78_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Diaminobutyrate--2-oxoglutarate transaminase</fullName>
            <ecNumber evidence="5">2.6.1.76</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DABA aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-oxoglutarate + L-2,4-diaminobutanoate = L-aspartate 4-semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11160"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58761"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="2.6.1.76"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.76" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2088"/>
    <dbReference type="EnsemblBacteria" id="ABX04728">
        <property type="protein sequence ID" value="ABX04728"/>
        <property type="gene ID" value="Haur_2088"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2088"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_0"/>
    <dbReference type="OMA" id="ELDQWKP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2116-MON"/>
    <dbReference type="UniPathway" id="UPA00067">
        <property type="reaction ID" value="UER00121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045303">
        <property type="term" value="F:diaminobutyrate-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047307">
        <property type="term" value="F:diaminobutyrate-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019491">
        <property type="term" value="P:ectoine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004637">
        <property type="entry name" value="Dat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012773">
        <property type="entry name" value="Ectoine_EctB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43552">
        <property type="entry name" value="PTHR43552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43552:SF2">
        <property type="entry name" value="PTHR43552:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00709">
        <property type="entry name" value="dat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02407">
        <property type="entry name" value="ectoine_ectB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="46741" checksum="AFC798424B9970AB" modified="2008-01-15" version="1">MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYGHNNPQIKQALLDYLESDQIIHGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGANAVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAEHRAAAGVPLAHTNFLPYPRGPLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIVLICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHTGTFRGNQLAFVGATAALDYWQTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVWGIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMPPLTIDSALLAQGCAILQQAIQTYLASTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC4</accession>
    <name>A9AWC4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ordered locus">Haur_2134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell envelope</location>
        </subcellularLocation>
        <text evidence="5">Is attached to the cell membrane when interacting with the MsrQ subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2134"/>
    <dbReference type="EnsemblBacteria" id="ABX04774">
        <property type="protein sequence ID" value="ABX04774"/>
        <property type="gene ID" value="Haur_2134"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2134"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045520_0_0_0"/>
    <dbReference type="OMA" id="WPYTEGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2162-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031975">
        <property type="term" value="C:envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="86"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="68"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="302" mass="33841" checksum="121679CA72A4DFDB" modified="2008-01-15" version="1">MKKIPSSEITPEALFYSRRQFIKGAAALVGSATVLAACGSETSETSDLPAGVDVQTPYESIINYNNFYEFTTNKEAVADASKNFTTNPWTVEVSGLVNKPQTFAIEDLLKQFTQEERVYRLRCVEGWSMVIPWTGFSLAGLLKQVEPTSAAKYVRFETVMRPEEMPGQSSSYYTWPYVEGLRLDEAMHDLTLMATGVYGKPILPQNGAPLRLAVPWKYGFKSIKSIVKIELVAEQPTSLWMNAAPDEYGFYANVNPDVPHPRWSQATERRIGEAGRRRTLAFNGYADEVAALYKDLDLKANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ7</accession>
    <name>A9AWZ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2165"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04805">
        <property type="protein sequence ID" value="ABX04805"/>
        <property type="gene ID" value="Haur_2165"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2165"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_470731_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2193-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="579" mass="65497" checksum="23656359027F181B" modified="2008-01-15" version="1">MQVSEHPRLRIAWLLTAPIVGSGGYTNIFRIMNLLASFGHEQVIFMNPHDYPTDALDRPEHFVQRYFGMVHAPIYFWPQDIRGFDVVLATQWTTTMGFEMCDPTIPRAYFVQDFEPFFYAMGDEWLRAEATYKQGWPCITLGHWLAKHLHEQYKATTYPFDFAVEHERYYPRPHLLTKKPRVIFYARPSTPRRCFDLGMRALAIVKEQRPDVEIVLFGDKHLSHHSAPFKFTAMGILNPDELAELYASATLGLVISSTNPSLMPPEMMASGCPVVDIDLAPNHFLVTHGKTGLLATAEPKPLAEALLNVLNDESLRQRLIKAGLEHAQTLRWESSAREVEKALLKLATTASGSLIQRLLTDHEHPNGDGVTAPLTGDFQVGQRLVCQHDGVCAFEVALAQPATGPWRLQLYDALINPNRTLVDVTSSTVNQQWLHFEFPPLPASRNQALHFVLSATNGSSLRFDFKASANGSLSFNAMPQLGQLCCRVLYQPAYDSTEPSVTPDVAYLTTQKALISSEYIQLSEFAERLHNLIVPKKSWQERGAKTWRMLRSGNFNGLAAEAKQYGRWVYDRAKQQLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX04</accession>
    <name>A9AX04_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2172"/>
    <dbReference type="EnsemblBacteria" id="ABX04812">
        <property type="protein sequence ID" value="ABX04812"/>
        <property type="gene ID" value="Haur_2172"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2172"/>
    <dbReference type="eggNOG" id="ENOG5032SJ9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137265_0_0_0"/>
    <dbReference type="OMA" id="NQIDTHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2200-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14592" checksum="D514903DEF8B5121" modified="2008-01-15" version="1">MSEAANAYYFSEGQVWRYHTRPNEPESAILINKIEYHSGLGAIFHISIAGVQVKNPHGEEPLTQLGHFPVVAASLEQSLTELVDTNVDNPSYLEGYESWREAFVQGKAGVFNIPVEQIISFVEEAINRSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX31</accession>
    <name>A9AX31_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2199"/>
    <dbReference type="EnsemblBacteria" id="ABX04839">
        <property type="protein sequence ID" value="ABX04839"/>
        <property type="gene ID" value="Haur_2199"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2199"/>
    <dbReference type="eggNOG" id="ENOG502Z9Y1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_273404_0_0_0"/>
    <dbReference type="OMA" id="KETHNIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2227-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1176" mass="127239" checksum="60A39CB7F213C41A" modified="2008-01-15" version="1">MSNSPVDLITLPTTNFSTDQISFQVSAELMQNSQQSSPISPTSNLAVVQDSAGKPMLFSIGTDQILHLIKYDEATPNGWQVIDLSTQWSKYSHAVAFDLSQDVNGLISITLALATADQTKTAVFTASMLSNDYTKTDWTKLSQQSKEIAGLDPTLQAESIRLGTSDDGHSPIIIIVGSINNAKFYYQVIDGQTSQTLQFPENVLSNPGSLLEVTAGHAIGQRAFFFLYQIGATQTLEATTLADQFQGSLQYDFSPGNAGIPAEYAHLTYTCMTTALGTQTSPLNISSDVYVGTTDGVYVFANSRLDGMQKITDAIKDVHQIIVTTAGDNIGLWVMASPSKLYYIAGKHGSPYTFNEPILFSDTVVHIAPTRSLLSKANELFVVDQQQQVVHYWQDPNTTLWSQRTISIADQSYLLNFNSYTTHIQLQDQNGMALANIPLAINCSTWSYATINGRIYSLDQDVLAQVPTDALGNLTIILPASDLTAPIIHVQADFIDQTLNIYPHGKISKGFQTIKSGDDLKNAKTADGSPVISGNFDSTALNSVAQNIGQLHQLSSQIVGPMGNNTYVVLTAKNTKQTGKLNSSQPVAKQLTMQVSRNRSVATLSLNSVDDIFDDIGDAFGDVWHEIEHFFVAGIDKIEQGITYLSNGVSFLIKEAEQGLNFILKVADKVYNIVLDSIASIYKVLSWIFQLIKVGIETLIKWLGFLFGWDDIWHTHKVLAQIISQGVNYGVNRLENEVNGWVESINTTFDQLNQQIHNTLVPSSLQSTTPHAITNNQGSDQQQQAFQSPGCNWSAYHLQHSGMLNGLGANLDHNPFIQFLNDVVIPTSQQLYAALENDIDDLKQIITGGVTISATLKLFADLATTIIEPIKTMLIGLLNFVVDLAKDIQHALVDDLDIPLLSDLYKWVTGLFGEGEDFSVVNGVCLLLAIPITIIYKASVGSAPFTDQSRVLDDPNLFTTIMGQPKQQLMLDTAKALNDSTIKSVGVVYSQVGGLLAAIVGPMITIANGFKLTATEQQVTVKSRAAKVSIVLAATKALLTFPVRKTGQSAAGYGLKITTWLLSILNTVQNAIIRNLSISGGIMAGIDLVIIIMALIADGLDHADGWTWTTDILSNVSGIVAGIGQIVKDSEEGLTIAIIGWGGSLFSSLIGGLAAVVKLNDGSDNEALQLINLGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB1</accession>
    <name>A9AXB1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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    <dbReference type="EnsemblBacteria" id="ABX06831">
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            <begin position="10"/>
            <end position="28"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="13475" checksum="5838835920596AB5" modified="2008-01-15" version="1">MSNTSLVKRLLHAEGLGLLLIAVLGYAWQGFSWWQFGLALFVPDMVMLGYLWGPKVGSLCYNFGHITLWPLSFLALGVLNDWPVGLQIGLIWLAHIGLDRMLGYGLKYPTQFKDTHLGRV</sequence>
</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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        <property type="gene ID" value="Haur_2281"/>
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            <end position="353"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="42050" checksum="15AE5E6D33995E86" modified="2008-01-15" version="1">MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRTNILLSQYSIERYKHFTEEIGGHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVLTPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLNKARELGVKVLRDAPALGFEFADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKDIPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAGLSERQSWAGSYEITPDHLPILGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRAHSIEIDELRIERFAAGELHAERNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD1</accession>
    <name>A9AYD1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="ABX03513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="16484" checksum="6DE91DB6EBC1E283" modified="2008-01-15" version="1">MHEAYEYRHIVGFEETNLVGNVYYANYVLWQGRCREMFLRDHTPELVQALAHDLALVTTSVSCEYHSELFAFDDVVIEMRLKELLQNRALMSFRYFRQNADSRTLVAQGEQGIACMRRAGNELQPEPFPAALRAALQRYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYG7</accession>
    <name>A9AYG7_HERA2</name>
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        <submittedName>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Woyke T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0901"/>
    <dbReference type="EnsemblBacteria" id="ABX03549">
        <property type="protein sequence ID" value="ABX03549"/>
        <property type="gene ID" value="Haur_0901"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0901"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_2_0"/>
    <dbReference type="OMA" id="TCWIERR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-915-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019120">
        <property type="term" value="F:hydrolase activity, acting on acid halide bonds, in C-halide compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02588">
        <property type="entry name" value="HAD_L2-DEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="25438" checksum="1454B3776BE29A83" modified="2008-01-15" version="1">MLNPAQFQVLTFDCYGTLIDWETGLWAALEPIFARYNINIEQEAALQLYGELESALEAGPYLAYKTVVATVLGQLGQRLGFTPTAEECAEFGLSVKQWPAFTDSPAALQRLQQRYKLAIISNVDDDLFAASEQRLGLKFDWIITAQQVQSYKPSLNNFQRAFERLALPQSAILHVAQSLFHDIVPANQLGLNTVWVNRRHSNPGFGATPAAEAQPDLVVPSLAALADALGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH9</accession>
    <name>A9AYH9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0913"/>
    <dbReference type="EnsemblBacteria" id="ABX03561">
        <property type="protein sequence ID" value="ABX03561"/>
        <property type="gene ID" value="Haur_0913"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0913"/>
    <dbReference type="HOGENOM" id="CLU_2898059_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-927-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="62" mass="6325" checksum="2FAA7567E313484A" modified="2008-01-15" version="1">MSDVKNLIDAEVTAGETELFADELEEHVTNAAAACVSSLGSLSTSGTICTVSTFCTAAIEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN4</accession>
    <name>A9AYN4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2372"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05012">
        <property type="protein sequence ID" value="ABX05012"/>
        <property type="gene ID" value="Haur_2372"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2372"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_337953_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2400-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018366">
        <property type="entry name" value="CBM2_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00561">
        <property type="entry name" value="CBM2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734427" evidence="4">
        <location>
            <begin position="25"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="30"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="842" mass="91768" checksum="D5CFA3B7E303280A" modified="2008-01-15" version="1">MLRRMYARGTLLVLLIALISLSVAHRTATPSAAAASCVVSYKVINQWADGFIGDVTVTNNLAATTTWQLSWTFAGNQRIVNLWNGVLTQTNAAVSVQNAAWNGSITSGGSVNVGFQATFSGTNSIPTSFTLNGVVCGETNVTITPPTSNPTNTATARPPTNTPMPPTGTPRPSNTPTIAPTTPTATPNNNGCIGAIICDDFENQTGIDPSGFWQALYPDCTGHGSVMVDNTYANSGSKSIMVHGHSNFCDHAFFGNTTAIESIGNLLYGRFYVRQDLALPDHHITLMALKDRNDADNDLRLGGQQGVLDWNRESDDATAPSMSSAGIAKSVTIPPRQWTCVEFKIDSANGYLQAWVNGSEVEGMRVDGVDTPDIDQAWRTRANWQPRLVDIRLGWESYGGDDITHNIWFDDVALATQRIGCSASNPTTPTATPRPTNTTTPVVGTLTPSPIPSATPTIAPNGITAATTIAELCPTYRQLYIDRDFLDYLPSDGSGGHNNMPVDGGMTDAQKASLYGVNISAIQSKIGNGTLTLGELGTQALGHVQRLVNQNFPKNAICQLLPRLMLLGPETETATFHKNSSNPWAETAGPVNAIAPAGFMQTRWPTDARTYVPAEKAERDRCHDQPVHENNLGWTFSSIVDPSILYDPNNPVLNAIRTSTHPISGLPMGPGFSSNAPMQATTKLHEENSGFWYQVIQFKNTSTIPYYLDCAMIWWVGPSGLSFDLRNGHYNNEQRPGRGYGHPQRDIIEVVYNQTQKLSVYSIRLSFHDEPYNMRTAYPNQYWSLEVGTPAFLNGQARYTTSAERQALMDLMLNTLHVELETNLDRNIELFDALKMRNRVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ01</accession>
    <name>A9AZ01_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4409"/>
    <dbReference type="EnsemblBacteria" id="ABX07041">
        <property type="protein sequence ID" value="ABX07041"/>
        <property type="gene ID" value="Haur_4409"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4409"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_4_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4464-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="44"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="22258" checksum="255D5982E4693340" modified="2008-01-15" version="1">MSRFGAEPLEFFQNVYNDVPPWDVAAPQPALIELINAFPPQNPILDVGCGSGDLAIGLAQLGYTAVGVDFVPTAIEQAQAKAAALPSEVAQRLRFLVGDGLKPSLLETKFGAIVDTGFYHLFNQADTEGFIDELAQALQPQGRYYLLAFGIEFASVNVPRAITEEEIRGRFTAERGWRVLDLQPAQFLNRVGPPVAALAACIERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ34</accession>
    <name>A9AZ34_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4442"/>
    <dbReference type="EnsemblBacteria" id="ABX07074">
        <property type="protein sequence ID" value="ABX07074"/>
        <property type="gene ID" value="Haur_4442"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4442"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_4_0_0"/>
    <dbReference type="OMA" id="YPKIGFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4497-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14939" checksum="7807EF132530B66D" modified="2008-01-15" version="1">MSIRYSTDVVISAEQFVAVLNASTLGERRPVDDLARIQTMLANADLIVTAWDGEKLVGVARTITDWCYAAYLSDLAVDQTYQKQGIGRQLIEATREKLGDQCSLVLLAAPAAADYYAKVGFEWIERGWQIKRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE1</accession>
    <name>A9AZE1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2447"/>
    <dbReference type="EnsemblBacteria" id="ABX05085">
        <property type="protein sequence ID" value="ABX05085"/>
        <property type="gene ID" value="Haur_2447"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2447"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_1_0"/>
    <dbReference type="OMA" id="DHCIFLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2474-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="47851" checksum="8C121458CA835A82" modified="2008-01-15" version="1">MQKVIIIGAGFAGLRAAKTLAGKKVDVLLIDQQNYHCFQPLLYQVATAGLEPEQIAYPVRGIMHNWPGVRFLMARVEQIDRASKHVVTTMGSFDYDYLIVAAGGQTNYFGNREIEQHSFGLKNLNDAEQLRNHLLSMFERAAYERDPQVRQALHTFVVVGGGPTGVELAGAIRELVKHVLVRDFPQLENSQVQVILLEATDKVLGMLPTRLQQKTLQRLEKMGVQVRLNTAVEGASADQVYLKGGEVIASHTLIWAAGVRGVELAQSLELALARGNRVQVQPDLRLADDPNVFVVGDLAYLEQAGKPLPQVAPVAIQQAVTAAKNILQQRQNQPTQTFIYRDRGSMATIGRNAAVAHIFGLQFWGFPAWVVWLFIHLMSLVGFRNRLVVLINWAYNYFFYDQAIRLITANRKQADFDVAPALDIMQTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH5</accession>
    <name>A9AZH5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2481"/>
    <dbReference type="EnsemblBacteria" id="ABX05119">
        <property type="protein sequence ID" value="ABX05119"/>
        <property type="gene ID" value="Haur_2481"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2481"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_563484_0_0_0"/>
    <dbReference type="OMA" id="HTINQWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2509-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="453" mass="51539" checksum="A49F4880ECD8175F" modified="2008-01-15" version="1">MSRLLICNIGNRDILLPMELLPVELHKASHRDKIKYIRTNKPKIGSSLQITMIKKVIDYLESDSIDWILLFGTQQANPNYQPTDTFEAAELMRELLIERWNFRPERVLAHAVPVNPTRQNELIRFYEAQLTQYDSQIQPSQVFLEVTGGTPAMSNALQLAGTEMFQARAIALYVTPDSMLPERLSIGRRILGGPLRKLIQANLTTFQYHAALDSWHLYRPYFTDLQSESSAKIIEGMLAHAAARVNLDVPRAILAIRDLVGLADGLYDVMIHELYNALTPLSHENALAEVLALAEIRLQSNNYADFLTQLVRYVENSLRLVCLYLNVPFINWQGKADPHGARVDDNWLKQQRIGTIKIGQSGLQRLLSMYAPNDPQVQLVLKFAKTCQPLIELRNEITHSLGGVSQTQIEQAFGDSASGILSYIHHNYQQLTQRSLNHNPYHTINQWINQLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ4</accession>
    <name>A9AZJ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2500"/>
    <dbReference type="EnsemblBacteria" id="ABX05138">
        <property type="protein sequence ID" value="ABX05138"/>
        <property type="gene ID" value="Haur_2500"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2500"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_3_0"/>
    <dbReference type="OMA" id="GCGTLWL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2528-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="370" mass="40458" checksum="8B51036F2F024D07" modified="2008-01-15" version="1">MSSVIIVGGGIVGCAVALELTQAGWQVTLIERDCLGSGATAAGMGHIVVMDEGEAQLKLTLFGQQLWQALTADHPQPHEYHACGTLWVATDTEEWDLVAEKAAVYQQYQIACEILDAAALYAHEPALREGLVGGLLVPNDSVVYPPKSAVYLWQQAEKHGATLVYGEVTTIQTNYVQLNDGRQLSADAIVVANGQRCIDLLPELPIRAKRGQLVITERYPALIKHQLVELSYIKNAHASSGDSVAFNLQPRPNGQLLIGSSRQFDRTDRQIDQLLLSQMLRKAIDYVPALADVRCLRTWTGVRAASPDGLPLIGQHPERAGLWLNVGHEGLGITTALSSARLLADQMLQRQSQLEIQPYLPRSLQQEQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZM3</accession>
    <name>A9AZM3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2529"/>
    <dbReference type="EnsemblBacteria" id="ABX05167">
        <property type="protein sequence ID" value="ABX05167"/>
        <property type="gene ID" value="Haur_2529"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2529"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_20_2_0"/>
    <dbReference type="OMA" id="PHAALWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2557-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="16112" checksum="FBC700226A261468" modified="2008-01-15" version="1">MSREYPNQPLIGVAVMVWHKQQVLLVQRAKEPLAGQWSVPGGAIELGETVEAAARREIREECSVEISQPRFITAVDVIHRDQTDQVQYHYVLLEMQAEWLSGEPQAGDDALAIAWFGVDDLIGLDIHPETRWLVETVAAQRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN3</accession>
    <name>A9AZN3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4455"/>
    <dbReference type="EnsemblBacteria" id="ABX07087">
        <property type="protein sequence ID" value="ABX07087"/>
        <property type="gene ID" value="Haur_4455"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4455"/>
    <dbReference type="eggNOG" id="ENOG5031FWX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1649802_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4510-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="18449" checksum="1A80CD900B3CE276" modified="2008-01-15" version="1">MHEISTIQQKLAALLGQVLWDGFEVAGILCLRIGEKRLITNRKQQEVEIGRYSLHISGVWRFWQHQQLIIADGDWAQPDPAGVEPSALHRFLHTFWPQSLFIRSIQLNSIGDVQLHLSQGYCLELLISSTNNEYWRLIDNDTDEHFIVEAHDDDDSTENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS5</accession>
    <name>A9AZS5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
    <sequence length="208" mass="22877" checksum="77F005892FC7BDEF" modified="2008-01-15" version="1">MPFGILNVGYDSTNYYLVGSTYGFLLVDAGWPGTWGKLLATLKRHDVDLAQIHSMLITHYHPDHAGLVQELKSKGIQLIVAEEQQPAIPLLKSLIKPEVNYQPITPEHTTIISLAQSREWLASIAIAGEIIHTPGHSADSISLVLDQGIAFTGDLQPYAADAESQALVENSFQALRERGVEWLYPGHGPMRPLIYTSQQVKLCPDDPS</sequence>
</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
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                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX07135">
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        <property type="gene ID" value="Haur_4503"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-4558-MON"/>
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    </dbReference>
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    </evidence>
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</entry>
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    <accession>A9AZZ7</accession>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="gene ID" value="Haur_1056"/>
    </dbReference>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03704.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="36021" checksum="B465D672F2691B57" modified="2008-01-15" version="1">MTKVRFSRFLSVFLLLGSLVACDAAENGVTQLPATTVPPTATTDSAAVAPTAELTPTETSSISYPLTIKDSLGREVTLQAAPSRIVSLAPSNTEILFAVGAGDALVGVTKYCNYPEAAKSIDQIGGFSAKTISLETIVALKPDVVFSGDESQQIVIDALTQANIPVIAIKAETFEAVYQNINLIGQATNHPTEAAQVVAEMQARIDAVTAKTSTLAAADKLSVFYEVYDEPLMTAGPQTFIGQMLELAGATNIFADVSEEYPEISAEEVVNRQPAVIIGPESHGDKLTIDLIAQRPGWGAIKAVKEGKIVVLNGDMLSRPGPRLADALEALSQALYPELFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B007</accession>
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        <submittedName>
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    <organism evidence="4 5">
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    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1066"/>
    <dbReference type="EnsemblBacteria" id="ABX03714">
        <property type="protein sequence ID" value="ABX03714"/>
        <property type="gene ID" value="Haur_1066"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1066"/>
    <dbReference type="eggNOG" id="COG2870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021150_0_1_0"/>
    <dbReference type="OMA" id="KTRISGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1083-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="16"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="35852" checksum="0277BBD802459F24" modified="2008-01-15" version="1">MCMITVEHVAQLANRRVLVVGDVVLDEYLYGKPERLSREAAIPVLEFEQRRIIPGGAANPAANITALGSNAGIVALIGADQAGQELANALHKRKVSTAGLLRDEQRPTTTKTRILASVQLTVAQQVARLDKIDRRPVDPAFEDQAIELLGQLIPQVDAVLCSDYRVGWLSERLIQHIQQLCQQYQTLLTVDSQGRFEPYAGADFLKCNLGEAEAWLGQRLTNDQQVEQGLERLRDQLKLAAVVITRGGAGFSLLDPAGIHHIPAVPIGEVFDATGAGDTFIATATLSLCAGHSPLIAAQLANTAAALVVRRIGVATVSPNELQNALIQFGQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B058</accession>
    <name>A9B058_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1117"/>
    <dbReference type="EnsemblBacteria" id="ABX03765">
        <property type="protein sequence ID" value="ABX03765"/>
        <property type="gene ID" value="Haur_1117"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1117"/>
    <dbReference type="eggNOG" id="ENOG502ZFYM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150256_0_0_0"/>
    <dbReference type="OMA" id="PTFRAQI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1138-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="133"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24921" checksum="E870BB067562AA22" modified="2008-01-15" version="1">MALTIYPWLIVVAIIAYALMVWMLANDPNILVQKQEAPKLAKITSRTFQSHLEAIDRTRREIVRSTNVTAGPLQRLLQPIADQANELFQQAHGLADKGQLIEQYLQTSQPHGLQPQIDNLDQRIAMTKDSYTVDQLKETRAALIDRQQNAQALATYYDRITAQLQNIAANLDNVLAETVRLRASEAASATQTSQEVAERLSNLNADMDAFQHVLEGAMSQSGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Q6</accession>
    <name>A9B0Q6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA methylase N-4/N-6 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1128"/>
    <dbReference type="REBASE" id="16520">
        <property type="entry name" value="M.HauORF1126P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03776">
        <property type="protein sequence ID" value="ABX03776"/>
        <property type="gene ID" value="Haur_1128"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1128"/>
    <dbReference type="eggNOG" id="COG0863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105964_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1149-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="28720" checksum="6CCBD44EC7A88F6B" modified="2008-01-15" version="1">MAIPPIIKIYPIGTNHISKLGQSEHCYGQHYGFGIVKLGWAAVHPVLERYGWRYVGTNIWDKGKAHIAGNVNTKQLRQFPVVTELCVQYIFEPKINGLSLKQWLLYEWRRTGLALREANRACDVADAATRKYLNQGHLWYFPPPERFELLVDYANSHGVVTGRPYFSIDGSRPATAAEWATMRAKFYCPYGFTNVWQRDALRNAERIKTPQGKVIHLNQKPLDLMERIIAASSDPDDVIWEPFGGLFNHCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0R3</accession>
    <name>A9B0R3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="9" type="ordered locus">Haur_1135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1135"/>
    <dbReference type="EnsemblBacteria" id="ABX03783">
        <property type="protein sequence ID" value="ABX03783"/>
        <property type="gene ID" value="Haur_1135"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1135"/>
    <dbReference type="eggNOG" id="COG0597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083252_3_1_0"/>
    <dbReference type="OMA" id="ASKLWLY"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18341" checksum="7C88ED67C8B6D701" modified="2008-01-15" version="1">MKLTKRYLSLGIMVLAILALDRWVKWWALDTLTPLGNPGHEPIPGILRLVYVENRGVAFGFLQNNSLLLGIMALGVIAFMLIRSRTWFGEAGLLGQISVAAIIAGGLGNVIDRFIYGFVVDMIHLIPLPIFQVFNIADMAISFGAVGLFITLWREDAAKRRSEQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0W3</accession>
    <name>A9B0W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1185"/>
    <dbReference type="EnsemblBacteria" id="ABX03833">
        <property type="protein sequence ID" value="ABX03833"/>
        <property type="gene ID" value="Haur_1185"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1185"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_19_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1207-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="21308" checksum="FDA177BF1601D7AC" modified="2008-01-15" version="1">MQLSTERGDLTLRAAQTDEWQAYRRLRLMALQQHPSFFGSDYAQNAAEPDRYWQERMANLDPTKQQTFVAVHESQFVAMVGIRRFTDPKSSHQADIWGVYTDPNWRGNGLSRQLLGMAEAWAWQQSVQIIRLAVNVANTSAIQLYTRCGYAVYGVEPMAIYYEGIYHDELLMTKKNIQHRTDLD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B168</accession>
    <name>RECO_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recO</name>
        <name type="ordered locus">Haur_2708</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B168"/>
    <dbReference type="SMR" id="A9B168"/>
    <dbReference type="STRING" id="316274.Haur_2708"/>
    <dbReference type="EnsemblBacteria" id="ABX05346">
        <property type="protein sequence ID" value="ABX05346"/>
        <property type="gene ID" value="Haur_2708"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2708"/>
    <dbReference type="eggNOG" id="COG1381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066632_1_0_0"/>
    <dbReference type="OMA" id="LCTQSET"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000099384" description="DNA repair protein RecO">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <sequence length="253" mass="28770" checksum="17CECD9B25F2FA96" modified="2008-01-15" version="1">MRDRLYTTEALIIRRSDVGEADRILTIYTPHHGKLSVTARGVRKMTSKLAGHLELFIHTRLQLAKGRSFDVVTESRVVQPFRSLREDLSRISQGYYVAELLDQMTPDESDNPALFRLTCETLAALDVLDDVVRRDVILRYYELHTLILSGYRPHLFDCANCERELSPDADRYSPITGGVLCQQCSSNEPRTLPINLNTFKLLRYLARMPLETVVSLVPAPATVQEARLVLKASLSQILERELKSTQFLNLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B174</accession>
    <name>A9B174_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2714"/>
    <dbReference type="EnsemblBacteria" id="ABX05352">
        <property type="protein sequence ID" value="ABX05352"/>
        <property type="gene ID" value="Haur_2714"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2714"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037113_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2745-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734480" evidence="1">
        <location>
            <begin position="23"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="387" mass="42156" checksum="F8C5BB2AA7B4E5B6" modified="2008-01-15" version="1">MDNRRLALLVSLCAVLFAFAVAKNPGLTNAKVRLTETPTPSEISIATSSSIVPSPNSTSIMTPTVICPTYYLFESDAQAHIPNSSPTRTPVPTPNIDPCYVHPTLFLNGPSQVNVGELFTLSITYENIGMQHTRIWFNDANLARFDPPLVMPCQYDRHPTRCERITLRATSVGTLVINADARGESFHYGWYWSSAAARTPLTINVIDPNGTPVPTPTCVPATLTPTSTAQPTYTPTVVGQRVPDLTETPTPSSTSTITPVPCQPAVSHQLILNAPSQVQVGDMFTMTVDYQNMSAPRMEIMLSSSELAQFDPPLTMPCRYSEHPTQCSTITLRATAPGMLTINGRAIADMFVGDGWTFGYTSARNPINVQVHDGLPYKLFIPLAKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E9</accession>
    <name>A9B1E9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4705"/>
    <dbReference type="EnsemblBacteria" id="ABX07336">
        <property type="protein sequence ID" value="ABX07336"/>
        <property type="gene ID" value="Haur_4705"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4705"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2167478_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4762-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="110" mass="11981" checksum="E8006AAE5BF326C3" modified="2008-01-15" version="1">MTDELDAIPWHTIDHAYGYATDTPQHLRNLTHPDPEVIQQSHSALSASIVHQGGVWPAALAAFPYLLRIFLTHSGHTCSCASALVMIIVKGIAPPIPSLIAYGYLLNKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J2</accession>
    <name>A9B1J2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1229"/>
    <dbReference type="EnsemblBacteria" id="ABX03877">
        <property type="protein sequence ID" value="ABX03877"/>
        <property type="gene ID" value="Haur_1229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1229"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_451122_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1251-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013211">
        <property type="entry name" value="LVIVD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08309">
        <property type="entry name" value="LVIVD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00801">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="601"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="675" mass="73268" checksum="2ED74AF5B6950B60" modified="2008-01-15" version="1">MHTHNGRWSRSLAVGFAVLAAFVLAPIASISAHSNHDHKIYVAPFGKDEGDCSKIWQPCATIDYAISRGTGKGDEIRVAAGDYSYDAQAVGLLLSRQIPVHGGFSARDNFMQQDTKANPTYIAGIPSRYRERLAAIGFARVEDRDGRNTPELERMQIPTELETPSAAQPCTNGMAGIFECNGIDFLGSVPLSSFRVNGSGATDGSNLWGHVDLNTDREYAIIGVNNGTGVVDVTDPTNPVVIGTVPGNNSQWREVKVYQYFNQAQNRWNAYAYLSTENRTQGLQIVDLNHLSDPTPSVSLAATYTADFGSSHTVYIKNVDFSTNVALPGKTAALYMNGVGKNGSRLSSGVFRAFDISNPLTPQIIDSGVPDTNISYTHDDTSMIITDSRTSACAPGHQASCEIMFDFSESSVEIWDITDSAAPFHISSRPYSGSGYTHSGWYSDDKMYVFIQDELDEQNFGHNTRVRTMDIHDLDNPTISATWDGPTRAIDHNGYTIGNKYYMSNYLRGLTILDITNPNNIQEAAFFDTYPGSNSASFDGAWGVYPYLPSGTLMISDISRGLILVREPTSTPDQAIAGLEATNDGPTVAGEATNFDAAIRAGTNVTYAWDFGDGTAVVTSTNTTMSHTYPNVGNYTVELTASNGTNSQTATTTVVVQAPPQTEWKIWLPFAIRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L0</accession>
    <name>A9B1L0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11 12">Xylose isomerase</fullName>
            <ecNumber evidence="4 11 12">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xylA</name>
        <name evidence="15" type="ordered locus">Haur_1247</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11 13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4 11 12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A9B1L0"/>
    <dbReference type="STRING" id="316274.Haur_1247"/>
    <dbReference type="EnsemblBacteria" id="ABX03895">
        <property type="protein sequence ID" value="ABX03895"/>
        <property type="gene ID" value="Haur_1247"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1247"/>
    <dbReference type="eggNOG" id="COG2115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060750_0_0_0"/>
    <dbReference type="OMA" id="IVEAWNT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00455">
        <property type="entry name" value="Xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013453">
        <property type="entry name" value="XylA_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02631">
        <property type="entry name" value="xylA_Arthro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="14">
        <location>
            <begin position="36"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX03895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="42307" checksum="9F71D67583FA2A44" modified="2008-01-15" version="1">MTQHKFSFGLWTVGNVGRDPFGEPVRKTLSPVEIVHLLAEVGAWGVNFHDNDLVPIDASASQKAQIIADFKQALKDTGLVVPMATTNLFGHPAFKDGAFTSNDPAVRAYALQKTMAAMDLGAEFGAKTYVFWGGREGSETDASKNLLEGLKWFREALNFLCDYSNAQGYGYRFALEAKPNEPRGDIFLPTTGAMLGFIQTLDQPEMVGVNPEVAHETMAGLNFTHAVAQALDAGKLFHIDLNDQNSGRYDQDYRFGAQNYKQSFFLVKLLQDAGYDGPLHFDAHAYRSEDLEGVKDFARGCMRTYQILAEKVQRFNADAEIQALLAQINAPNADVEQFRGGYTPERAAALKAYQFDRQALGERGLGYEKLDQLTFELLMGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N0</accession>
    <name>A9B1N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator receiver sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1267"/>
    <dbReference type="EnsemblBacteria" id="ABX03915">
        <property type="protein sequence ID" value="ABX03915"/>
        <property type="gene ID" value="Haur_1267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1267"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_72_0"/>
    <dbReference type="OMA" id="EIAIIIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1289-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="17"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="307"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="542" mass="60412" checksum="37EB4ED2ED253324" modified="2008-01-15" version="1">MTERQPNEASEYSRAPAILVVDDDTSICRYCSKALRNVGYQVVDTTSGLVALDHLRHQAFDLLLTDIKMPEMSGLELARQARALNPGLAVIIMTGQTTLETLREAVQQGVTSYLSKPFEIEEMRLTVAQVLHQRAMVLQKVKLEAIVHQLELSSAFNRTLSLSELCGEIVRVTNSEIGCQFGYFLLQQPDESPRLLMGQASHPQLNEAGWQLLQETYQQQQPIQTTLKLAEADHNVITFPLRVGGAMIGSALFDYTEALPSAQIEGMMLLLNQAAAALNNAQLFTRVQEANSRLQELDRLKSEFISITSHELRTPLAVVLGYGIVIQERSEPPIRTYLDRLVESAQRMKEIIDDMTHLRRLDTRQTELQLEPIVLDELLYEVIDQMHGLAQKKSQTLSLATPPDALCTLYADRAKIALVLMSLLSNAMKFTPAEGMITVRAWCETVQSVPYEHAYFKGTLQPGPWVFVSVSDSGIGIPESHLQRIFERFYQVAQSLTREYGGTGVGLALVQGLVALHNGHVWVQSEEGRGSTFTVALPQRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B233</accession>
    <name>A9B233_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4752"/>
    <dbReference type="EnsemblBacteria" id="ABX07383">
        <property type="protein sequence ID" value="ABX07383"/>
        <property type="gene ID" value="Haur_4752"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4752"/>
    <dbReference type="eggNOG" id="ENOG5034BYC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1189194_0_0_0"/>
    <dbReference type="OMA" id="ERWSVFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4810-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="28479" checksum="EFBA63B1EE0952B7" modified="2008-01-15" version="1">MVRRPDLEEVRVNTFLIADTAMIPILRGEGTVNGHSFTLTSVRGQGLIARLRTRNYRVVTLKDKIDRLTELPTVEAPGNLLQIETGARDQWFHFDSDTLTWQAVEAQTNGSRLFVAFEEHRVARRRRSRTSGDYFRIERLPNGTPQLTPIKEDTALLLGYAHATYEADIEIDNTANADGSYSLPVEFSLPPAYRTMLELLAESHDKQTMHFSAAGWPLAVRLLHRLNLRPANGDIEDDFGDDHDDFDDDDE</sequence>
</entry>
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    <accession>A9B280</accession>
    <name>A9B280_HERA2</name>
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        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="7 8">
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            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
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    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX07430">
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        <property type="gene ID" value="Haur_4799"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG2814">
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    <dbReference type="OMA" id="IGIGDHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4858-MON"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
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    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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            <end position="34"/>
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        <location>
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    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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    </evidence>
    <sequence length="405" mass="43000" checksum="44B9D18A94A4FAFB" modified="2008-01-15" version="1">MQQVPSTHVRHPMWPIYLCVAVTALGIGIINPLIPHLLEQNGANEFIVGLSTSVMFASLVLTGMPIGRTIDKFGIRLFLIVGLISYTVAMLAMPWTHSIPLFFMWRIFEGIGWSCVWTAAETYVSRVSSPAQRGHNTAVYGMSLASGTAAGPIIGTAVYEWTKNPVHPFLVAVAAAIIATVIVVLVVPEPHVHHTEQESGGVSFKITRPLILPLAIAFLYGYGTLSLVSLLPTLNYSNWELGTLISVTVIANIVAQVPIGRMLDRYGYRPLLIGSLSLLSAAALFSTLHPPFLLTLFLGMLLGAFAGTLYPIGLAVLAARVPPAKLGGASGMFTVCYGLGSFVGPALTGGVMSMVGAKHSDQALFGTIGCLVLALLGLMMTGIDRVNVKEEHPVSVASSGIKPPM</sequence>
</entry>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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    <dbReference type="EnsemblBacteria" id="ABX07434">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="623" mass="69702" checksum="E9C0B7F2747E4B04" modified="2008-01-15" version="1">MQFKRFVWVSLGLAGLSLMLLVGNTLSLRLFGQIQQIDVGNWGDQNNVAGGFEQEQNALGETYRWTQAEATIRLQGYGSASSRLLSLKIGGVPSSLPVTATMQVSTNSASVALPLTQTARHYHLLIPPTYQPDWQVRLNIPTQQVLPDPRFLGVRLDHVQIQTPSIAWSSVHWHLLIVQLAIMSSLIGVLWFLAADWPTIVGISGITILVLVTITGKFVLVAWAWQLRLLIVAAATTLLVGWLRSLIQNQIKHLLKPYEYRYLIIFSVISFFIPVMSILFPNFGSHDRVIHADRLGQVAQGSALLLDKLYEFQGRETITPTTFYLLALPLTVFFNNNGLIIEGLYTFLHASSGILLAITLLRWKVRPILALAAMILISAMPIQMTILWWGFAPQIVGQWLILVFLAVFSFQSTLRPTIISIGILSLAIWMHNGVALLAGTWIASYCALGYWRDPAQRRHYWAWFLNLIGISIFGLLAIYIDLFMTTGTTQQQVLGLTEYLPAVINGLSASFAPIGIMFVAIFGLLPFLQLEKNKKILLIASGLTFLLFLAIDIVFGVQVRYSYFILPFLLMIGIIFIDQRLSIIPYVESVIITLTLLCYGYSLYSWYDAIIYGVKPSLLGLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B285</accession>
    <name>A9B285_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4804"/>
    <dbReference type="EnsemblBacteria" id="ABX07435">
        <property type="protein sequence ID" value="ABX07435"/>
        <property type="gene ID" value="Haur_4804"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4804"/>
    <dbReference type="eggNOG" id="COG1768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1183887_0_0_0"/>
    <dbReference type="OMA" id="NHDYWWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4863-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014578">
        <property type="entry name" value="Pesterase_CT488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033094">
        <property type="entry name" value="Pesterase_CT488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26149" checksum="FBFC033615D32D14" modified="2008-01-15" version="1">MRIWAIADLHLAGGQDKPMDVFGAHWRNHAATIAKAWHESVAADDLVLIAGDISWAMHLNDVRADLAWIEALPGKKVLCKGNHDYWWSSKNKVRAILPPSLQIVDCDAVVVDQIVVCGTRGWAVPGDRDFDKTTDQRIYERELGRLERALAGAQVLAEEARPIYVLLHFPPFRDGQPTEFAKRIAAANAHTCVYGHLHQAEQWANATTGHVETVFYQLTACDALGFKPLLLTDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B287</accession>
    <name>A9B287_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4806"/>
    <dbReference type="EnsemblBacteria" id="ABX07437">
        <property type="protein sequence ID" value="ABX07437"/>
        <property type="gene ID" value="Haur_4806"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4806"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080384_1_0_0"/>
    <dbReference type="OMA" id="DGNMARQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4865-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="216" mass="23932" checksum="0A7325277A9BC61A" modified="2008-01-15" version="1">MYSTGIKRWARRLMEHFVAPVLSRLGITPNMVTLIGVLLTAGVAAVLANGSLQVGGVLLILSSIFDLFDGALARATNQSSRFGAFFDSIMDRYSEAVVFFGLLIFIHTKMVGATTLALTLVYCSIIGSIMVSYARARAEGLSIPCETGWLGRPERITILCTCLILNWLMAGLWILAIFTNITAIQRIYHVWRTEQIANPQPKPVKTNRWNISRKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L3</accession>
    <name>A9B2L3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05464">
        <property type="protein sequence ID" value="ABX05464"/>
        <property type="gene ID" value="Haur_2826"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2826"/>
    <dbReference type="HOGENOM" id="CLU_2081590_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2857-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="117" mass="13986" checksum="7ECD9BC1F37BC96F" modified="2008-01-15" version="1">MKIYWSNNSVPELQGLDKHKQLDLRFRAVKANRHNPRLWLGLVAVFSVYLGILAFLLYAIPFSGIQILIQITLMLLFHFWFNQYLIWLIRPHLRLYRLALDKTYSNDDDDYFVPPAY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Q6</accession>
    <name>GCSH_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gcvH</name>
        <name type="ordered locus">Haur_2869</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="1">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B2Q6"/>
    <dbReference type="SMR" id="A9B2Q6"/>
    <dbReference type="STRING" id="316274.Haur_2869"/>
    <dbReference type="EnsemblBacteria" id="ABX05507">
        <property type="protein sequence ID" value="ABX05507"/>
        <property type="gene ID" value="Haur_2869"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2869"/>
    <dbReference type="eggNOG" id="COG0509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097408_2_0_0"/>
    <dbReference type="OMA" id="YRDSHEW"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0450">Lipoyl</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114522" description="Glycine cleavage system H protein">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01066"/>
        </source>
    </evidence>
    <sequence length="129" mass="14217" checksum="E6E84DE6ED0C551A" modified="2008-01-15" version="1">MSNVPHELLYTKEHEWVRIDGNSAVVGITEHAQRELGDVVFVELPDVGKSFEVGEPFGTVESVKAVSEIYAPLSGEITEINNEVVDSPELVNEDPYGEGWLAKFSFTTAPSGLLSAAEYERYINDEANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T7</accession>
    <name>A9B2T7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2900"/>
    <dbReference type="EnsemblBacteria" id="ABX05538">
        <property type="protein sequence ID" value="ABX05538"/>
        <property type="gene ID" value="Haur_2900"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2900"/>
    <dbReference type="eggNOG" id="COG4149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_1_0"/>
    <dbReference type="OMA" id="HWLAGAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2931-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006469">
        <property type="entry name" value="NifC_ABC_porter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01581">
        <property type="entry name" value="Mo_ABC_porter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="52"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="28471" checksum="265ED75BB3DD14E9" modified="2008-01-15" version="1">MGNNRFRRSFWLILSSMPLLGFLLIPLIAVALRVPIEALASTFAKPAVREALSLSLLTTSSSMLITLVFGTPIAILLARPRFRGQALLDTLIDLPMILPPSVAGIALLMAFGRRGLLGQYLRLIEIELPFTTAAVVLAQVFVASPFYIKAAAAAFATIDHDLEDAAALDGANSRQIFWFISIPLAWTGVVSGAVMTWVRALGEFGATIIFAGNFVGRTQTMPLAIYQGFEQDLNVALILAMLLLVISFMILGLVKGLLAQRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T9</accession>
    <name>A9B2T9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2902"/>
    <dbReference type="EnsemblBacteria" id="ABX05540">
        <property type="protein sequence ID" value="ABX05540"/>
        <property type="gene ID" value="Haur_2902"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2902"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052659_0_0_0"/>
    <dbReference type="OMA" id="EPMFFLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2933-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017196">
        <property type="entry name" value="ECF_substrate-spec_UCP037395"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024529">
        <property type="entry name" value="ECF_trnsprt_substrate-spec"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12822">
        <property type="entry name" value="ECF_trnsprt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037395">
        <property type="entry name" value="UCP037395_ABCper"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="29311" checksum="F5B701ECACBA5914" modified="2008-01-15" version="1">MSRATPFASRILVGVTSLIGLVAFFYPFFLSEVQAGDNHAADAPLIMLLLGPLLLGIILADLNSHAMNSRVVAALGMLVAINAVLRLPAGPGDSPTFFFLVILAGFVYGGRFGFLLGSLSLAVSALLVAGIGPWMPFQMLAMGWLGLSTALLQPIKRWLKLADAGWGEVVLLAIFGWVWGLLFGGLMNLTFWPFSAGESAISWQPGLGFGPTVERYWAFYLLTSLGWDATRAFFNVLLIMAFGKPILAVLRRFQLRLNWQTQESIEQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Z7</accession>
    <name>A9B2Z7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4830"/>
    <dbReference type="EnsemblBacteria" id="ABX07460">
        <property type="protein sequence ID" value="ABX07460"/>
        <property type="gene ID" value="Haur_4830"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4830"/>
    <dbReference type="eggNOG" id="COG2308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045981_1_0_0"/>
    <dbReference type="OMA" id="FCELNAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4889-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="453" mass="51058" checksum="CAB7F24CFE6420CA" modified="2008-01-15" version="1">MLEQAIRDYHALLTPDLARASQERLTNLQQQQNLFFGTRPLCNVLRPHFLSVEQSSLIERVSQLVAEASRTVVEYALRTPEVLDLLALTEGEHQLISYEPGYRELSVSSRLDSFLTSDSSSFQFVEYNAESPAAIAYEDILSQVFEQLPIMQEFQRHYRVESLPARQRLLEAFLAVYREWGGTGEPKIAIVDWHGLPTLSEFQLFQQYFAEHGLKTVICAPEDLRYQAGTLYANNTPVNFVYKRLLTTEFLQRLGNEAFDHPLTQAYRDGAICLANNFRAKLLHKKMIFGLLSDPAITSAAGISSATQQQLAQHIPWTRRVTAGRTDYAGTEVDLLDFIRQNRDRLLLKPNDDYGGHGITIGWETEAEAWDLALQQALTEPFVVQERVVIAYEDYPAMVDGQLQIGQRLVDTDPFLFGSEVQGCLTRLSTVTLLNVTAGGGSTTPTFQLSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B331</accession>
    <name>A9B331_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phage shock protein C, PspC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4864"/>
    <dbReference type="EnsemblBacteria" id="ABX07494">
        <property type="protein sequence ID" value="ABX07494"/>
        <property type="gene ID" value="Haur_4864"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4864"/>
    <dbReference type="eggNOG" id="COG1983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099432_0_0_0"/>
    <dbReference type="OMA" id="GAYFEID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4924-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="20482" checksum="B22C8997CFF32AF5" modified="2008-01-15" version="1">MQPRLLRSYYDRKLAGVCGGLGAYFEIDSTLVRLVMILLVFTGLTFLIYPVLWLIMPSEKPGAMPPPFMPQQQAGVVPPPQQPFNNVSSPYRYDPFTGQPIAEQPEAYTGTTVQVRPDQYIPPYSQAQQPAHAPRSTRNNKKVLGLLLLAFGLITFIDKFGGAAEFITPLLLIGLGIMLFRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3D2</accession>
    <name>A9B3D2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1451"/>
    <dbReference type="EnsemblBacteria" id="ABX04095">
        <property type="protein sequence ID" value="ABX04095"/>
        <property type="gene ID" value="Haur_1451"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1451"/>
    <dbReference type="eggNOG" id="COG0538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1473-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="11948" checksum="BD31C7F2B806E37B" modified="2008-01-15" version="1">MYGDILSDLCAGMVGGLGVAPGGNIGEHGAVFEATHGSAPKYKNLNKVNPTALILSGELMLRHLGEIEAADRLNAAVATVIAEGKDVTYDLKDDRNDPSAVGTAEMADAIIAKLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3D6</accession>
    <name>A9B3D6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine desulfurase family protein</fullName>
            <ecNumber evidence="2">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.1.7" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1455"/>
    <dbReference type="EnsemblBacteria" id="ABX04099">
        <property type="protein sequence ID" value="ABX04099"/>
        <property type="gene ID" value="Haur_1455"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1455"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_2_0"/>
    <dbReference type="OMA" id="PYRLIDI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1477-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011340">
        <property type="entry name" value="Cys_dSase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01976">
        <property type="entry name" value="am_tr_V_VC1184"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="25"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="308"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="45793" checksum="0CCE9527EE24CA8D" modified="2008-01-15" version="1">MTVDLAPFRSHFPALTQTHAGKPLVFFDNPGGTQVPQQVIGQMTDYLRRSVANTHGAFITSQRTDAVIDECHAGLAALLGGEPDEIVLGANMTSLTFALSRSLAREWQAGDEIILTTLDHDANVTPWLLAAEERGVIVHFVDINPVDCTLVMSDFERYLSPRTKLVAVGWASNAFGTINDVQTIVKQAHAVGALCFVDAVQSVPHIPCDVKALDADFVACSAYKFFGPHVGVLWAKREHLERLFAYKVRPAPETLPSRWETGTQNFEGQAGINGALEYLGGLGVGYMERYDQLLGETVGQRAVLLSAMHAIAEAEQSLGQYLIQALQTLKGVQLYGILEPERGHLRVPTVAFRKAGVTPQAIAKTFGNEGICVWDGHYYALRAVERLGLLDQGGMVRVGLAHYNTRTEIDRMLNVLESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R4</accession>
    <name>A9B3R4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2998"/>
    <dbReference type="EnsemblBacteria" id="ABX05636">
        <property type="protein sequence ID" value="ABX05636"/>
        <property type="gene ID" value="Haur_2998"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2998"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014042_0_0_0"/>
    <dbReference type="OMA" id="DCFCHTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3030-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_3" evidence="5">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="166"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="397" mass="44207" checksum="DD20633DC5FA4022" modified="2008-01-15" version="1">MAARSMPTINLPTQLKAHLQAGHPWVYRDHVPPSTRLASGTWVRLHCGNWQGFGLWDARSPIALRIFSSRMQPDANWIKTVVQQAWQAREPLRQTATTAYRLLFGEGDGLPGITIDLYNQYAVIATYADCVEVLIADVVKALQASVPQLRGVVRRRRDDSENDDETGKIELLWGELPPAQLIVEEHGLKLIANLFEGQKTGLFLDHRENRHTIEQWSHGKTVLNCFSYTGAFSLYAARGGATATTSVDIAPAAAHDAEQNFMLNGLMNEHQRFLARDCFDFLSRTIQRGETYDLVILDPPSFARSKKNIHAATRAYVKLNALAIQCVAKGGLLASASCTSQLSPANFRLMLGEAAAQTDQQLRIIHEAGQALDHPVPAHFTEGRYLKFVLARVDERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z7</accession>
    <name>A9B3Z7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3497"/>
    <dbReference type="EnsemblBacteria" id="ABX06133">
        <property type="protein sequence ID" value="ABX06133"/>
        <property type="gene ID" value="Haur_3497"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3497"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="VACHWAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3534-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="12"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="36488" checksum="38EA1FC4494E0E97" modified="2008-01-15" version="1">MTVSNSTSENLLEVRNLKKYFPIKGGLMRRTVAQVKALDGVSFSIKKGETLGLVGESGCGKTTTGRTVLRLIPPSGGEVLFEGQDVLKASSSRMRTLRRDMQIVFQDPYASLNPRIPVGQSIAEGLTIHNIGTPKERLDQVAQVLDRVGLNSGHMRRFPHEFSGGQRQRIGIARALVMQPKLIVCDEPVSALDVSIQAQVLNLLNDLQKDLGLTYLFIAHNLSVVEHISNRVGVMYLGRMVELASRDQLFRKPMHPYTKALMSAIPLPDPTIKRDRIILEGDVPSPVNPPSGCRFHPRCWLAQDICKHDDPIFEEKEPGHFVACHFAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B418</accession>
    <name>A9B418_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="13" type="ordered locus">Haur_4921</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4921"/>
    <dbReference type="EnsemblBacteria" id="ABX07551">
        <property type="protein sequence ID" value="ABX07551"/>
        <property type="gene ID" value="Haur_4921"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4921"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_0_2_0"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX07551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="25681" checksum="6214BA9110C95B38" modified="2008-01-15" version="1">MHPNGFRLGIIKDWKSKWFAERNYTEQLHQDLALRKYIEGADELKNAGVALVDIERSANRVEVTIHTAKPGIVIGKRGANVDTLKNQIEKLTGKKVRLNIQEIHQPELNAYLVAESVAEQISKRVSHKRAMKQATQRAMRLGAQGIKVKCSGRLGGAEMSRSLWEREGRVPLHTIRADIDYALVHAHTTYGRIGVKVWIYKGDVLGQRERQSATAAADAPKTNTRSGKGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B423</accession>
    <name>RL5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplE</name>
        <name type="ordered locus">Haur_4926</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B423"/>
    <dbReference type="SMR" id="A9B423"/>
    <dbReference type="STRING" id="316274.Haur_4926"/>
    <dbReference type="EnsemblBacteria" id="ABX07556">
        <property type="protein sequence ID" value="ABX07556"/>
        <property type="gene ID" value="Haur_4926"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4926"/>
    <dbReference type="eggNOG" id="COG0094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_2_1_0"/>
    <dbReference type="OMA" id="ERMYAFL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142412" description="50S ribosomal protein L5">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <sequence length="179" mass="20004" checksum="83DFEFC3165A6958" modified="2008-01-15" version="1">MARLKDVYLKTVAPALFKDFGFKSPMQVPRITKIVINIGLGEALQNPKAVEAAIGDLTMIAGQKPVVTRAKKSLAAFKLRQGMPIGAMVTLRNDRMYDFYDRLVNLALPRIRDFQGLSRKSFDGRGNYSIGIREQIIFPEIEYDKVDKIRGLEVAIVTTAPNDEQGFALLKALGMPFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A9</accession>
    <name>A9B4A9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="17" type="ordered locus">Haur_0014</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0014"/>
    <dbReference type="EnsemblBacteria" id="ABX02666">
        <property type="protein sequence ID" value="ABX02666"/>
        <property type="gene ID" value="Haur_0014"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0014"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013501_3_1_0"/>
    <dbReference type="OMA" id="LMWPIRD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="255"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="14">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABX02666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="645" mass="72930" checksum="1C5F6A2D7448B7E0" modified="2008-01-15" version="1">MNSVIDDIKERIDIVSFISDYVPLRKAGRNWVGFCPFHSNTRTPAFTVFADSNSYHCFGCKASGTIFDFLMQREGIDFPEALNQLAARAGVQLRQRTAQDDQEDVLRSRMLELNAAAARFWSHQLLQSPKAAHVRSYIEQRGLTPQTVEQFQLGYASEDWSSLLGYLHDRHGANPSEVAEVGLALEREQGGYYDRFRGRLMFPIHNAKGQIVGFGGRILGDGHPKYINSPQTLLFDKSSLLYGLFQARETIRSTDSVVVVEGYVDVIMAHQAGFRNVLAPMGTALTDVHAGQLNKMTKRITLAMDGDAAGQSAALRGLETLRETLDTHVRPVPTASGMLRWERELDATIKIALLPDGRDPDDIVRNNPEEWRSLIANAQPLMDFYLATLTRGLDLNSAKGKSTAVERLTPLLNQIADPVEKAHYIQRLANQIKIDQRLIEGSIGGDQPERQRKPNHRQSRPAAPPPVFSILEQEARREDFLLSLLIRFPQVQAVVSEQLRDDLAAAPTLRELWSGDVSELFERVENRVLWDLWRSAQAMATPNPIEWLETVPAELQAHGERLLNWDHAPPTRSFRVTREAEECLRPLRHRLGKRWSDRLGQIIAAAEPDQQERLLEQAMAIQHYLRATSEPRRSSYFLDTRDSLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H8</accession>
    <name>FTHS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="1">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="1">FHS</shortName>
            <shortName evidence="1">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fhs</name>
        <name type="ordered locus">Haur_1499</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B4H8"/>
    <dbReference type="SMR" id="A9B4H8"/>
    <dbReference type="STRING" id="316274.Haur_1499"/>
    <dbReference type="EnsemblBacteria" id="ABX04143">
        <property type="protein sequence ID" value="ABX04143"/>
        <property type="gene ID" value="Haur_1499"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1499"/>
    <dbReference type="eggNOG" id="COG2759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_0"/>
    <dbReference type="OMA" id="CGEIMTM"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000146685" description="Formate--tetrahydrofolate ligase">
        <location>
            <begin position="1"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <sequence length="570" mass="60778" checksum="98957634815C5115" modified="2008-01-15" version="1">MKTSLQIAAEATPRPITQIAEELAIAEQFVEPYGRYRAKINLDLLDASHDRPRGKQILVTAMTPTPLGEGKTATTIGLGMALSRLGKRAICTLRQSSLGPVFGIKGGGSGGGYSQVIPLEDSLMHLTGDIHAVTQAHNQIAAMTDNSWYQKNRLGIDPEQIQIRRVLDVNDRFLRSITIGQGGSQHGIPRQTGFDITAASELMAILALVSGENHADVMRDLRQRIGRMVVAFTRQGQPITADDIQAAGAATVIMRNAIHPTLMQTIENTPVLMHGGPFANIAHGNASVVADQVGLRIADYVVTEAGFAMDMGGEKFFDIKCRAFDAKPAVVVLVATIRALKAHSGRWNIKPGRDLPTDLLQENPDAVYAGGANLQKHIRNAQLFGLPVVVALNSFPDDHPSEIEAVREIAMSAGAFDVAVSKVFSQGGVGGEELAEKVLAAIDQAGQAQFLYELEQPLTAKIATIATKIYGAAEVSYSEAASEQLAKLEANGFGNLPICMAKTHLSISHDPALKGAPTGYSFPIREVRASIGAGFIYPIAGDMMTMPGLSANPAAQQIDIDEHGNTVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T6</accession>
    <name>A9B4T6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="10" type="ordered locus">Haur_3021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3021"/>
    <dbReference type="EnsemblBacteria" id="ABX05659">
        <property type="protein sequence ID" value="ABX05659"/>
        <property type="gene ID" value="Haur_3021"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3021"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_0"/>
    <dbReference type="OMA" id="VEICVYE"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="8">
        <location>
            <begin position="23"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="9">
        <location>
            <begin position="208"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="508" mass="57957" checksum="3B7267DA8933F03C" modified="2008-01-15" version="1">MEQPNPLRAGLRIARTPEACTVVIFGATGDLTARKLLPALYNLAREGMVPAGFSLLGVGRRPWSDDDFRAEMRKSAEQFSRVQPINEEVWQTFAEGLFWVGGEFGDINTYEQIASRLEQIDQQRGTAGNRLFYLAIPPSWFDDAISNLQKVNLTNQSHGWSRIIVEKPFGHDYKSAQELNDLVSRAFDESQVYRIDHYLGKETVQNLLVARFANAIFEPIWNRNYIDHVQITVAESLGIGSRAGFYEEAGALRDMITNHMMQLLTLTAMEPPVEFNEHEVRSEKVKVLHAIRPMNATDVDQFALRAQYDHGTINGDEVPSYLAEKGVNPASRTPTFVALKFEIDNWRWAGVPFYLRTGKRLAKRVTEIAIQFKKPPLLLFPEIRDDIESNVLALRIQPNEGITLKFSAKQPGQRMIIHPVNMDFRYGSSFGVAAPEAYERLLLDAMLGDATLFTRRDEVEAQWALMTPILERWENDGVEHLPHYEAGTWGPEESDQFMQRDGREWRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V4</accession>
    <name>A9B4V4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_3039</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3039"/>
    <dbReference type="EnsemblBacteria" id="ABX05677">
        <property type="protein sequence ID" value="ABX05677"/>
        <property type="gene ID" value="Haur_3039"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3039"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_377134_0_0_0"/>
    <dbReference type="OMA" id="ANMHANI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3071-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="12"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="442"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="557"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="601"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="709"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="735" mass="77053" checksum="A23DF5CF8BD5C925" modified="2008-01-15" version="1">MESFEHTQLGEYSLQDEIGRGGMALVYRAHHPDYGSVAFKVLPPYFAHDTDTLRRFMLEARAIRELHHPHIVQLYEASDIPDPNNSRQRIHYIAMEFIGGGTLSERLHTQPRQQLNPTIEMGLHIGSALDYAHRKQFIHRDIKPSNILYRHDGHAVLADFGIARVSNEARMTKTGGFAGTVAYTAPEIAEGQIADARSDIYALGLILYEALAGKNPYANMHANIAVALSKIISTPLPPLRELAPHVPPLTAQIIERATAKDPERRFENMSDFVEALKQAKFGRSATKPDVQLNAHGKPMIPIARPSGSRTERSSEGDSTRTQVFNPVVGAASAANVAISKPNQGLAGPASGANMALPVEGSQIYTPPAGSGPNSRINQPLSGVNQPLPMGANSQANVALPNDGTQIYTPEPVGALSGTNMALTGESTQMYAPVSGVNQPLSGVNQPLTGQNPVRGPSSRPNRTVNARPIEVARPGTAVNQNLGPSSQPNLGFDGGSGTFAVNRPNNNKKKALIAGIGGGILGLILIGVYMLSSSNTVNPNDTNGTTNAVQFTTDGSATATSASTSNGNGTPVGTQPAVVVDPGVATSTLAPTPENSPTPEPTDTPVATATSNAVVVATTRPQATNRPRPTNTPSQQQASPVPPTNTPPPADSDGDGVPDEVDGCPGVAGPNNGCPIPTEVPQPTPIPDSDGDTIPDNVDNCPNEPGDPARGGCPKPPATNTPRPTEKPTPPPINP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B546</accession>
    <name>HEMH_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferrochelatase</fullName>
            <ecNumber evidence="1">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemH</name>
        <name type="ordered locus">Haur_3547</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B546"/>
    <dbReference type="SMR" id="A9B546"/>
    <dbReference type="STRING" id="316274.Haur_3547"/>
    <dbReference type="EnsemblBacteria" id="ABX06183">
        <property type="protein sequence ID" value="ABX06183"/>
        <property type="gene ID" value="Haur_3547"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3547"/>
    <dbReference type="eggNOG" id="COG0276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018884_2_1_0"/>
    <dbReference type="OMA" id="LGDPYHC"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0350">Heme biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000116052" description="Ferrochelatase">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <sequence length="305" mass="34315" checksum="A9504E5B5D67E6D6" modified="2008-01-15" version="1">MSAKTAVLLMAYGTPNRIDEVEQYYINVRGGRMPTPEQVENLSARYRAVGGHTPLTTLTKSVTDQLQAQLDAEFPDQYQVYFGMKYWHPLIPDVVKQIHADGISKVIGLALAPHYSKISIGGYQKQVDRANEEFNTNIELTMINSWQEQPKFRNLIANRISEALAQFPADVRDQVTVLFSAHSLPQRVLAWGDPYPDELLGSAKGIAEMLELPDWRFTYQSQGETGEPWLGPDVLDTLAELAAEGKKYVLQVPFGFVCDHLEILYDIDIEGKHKANELGLQLERIRLLNDDPAFVDLLKTVVTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B582</accession>
    <name>A9B582_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3583"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06219">
        <property type="protein sequence ID" value="ABX06219"/>
        <property type="gene ID" value="Haur_3583"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3583"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046109_0_0_0"/>
    <dbReference type="OMA" id="RISAGNM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3622-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="44544" checksum="162A6B3BC05FEAC4" modified="2008-01-15" version="1">MIAALFWLFTGSVIYTYAGYPALLTLLARFRRERGPYPHAEPAVTLLIAAYNEEAEIARKIENSLALDYPREQLQLLIIADGSSDRTPEIVQQYADRGVELLYEAPRRGKMAAINRAIPFVRGEIIVFSDANNRYDANVIRELVAPFADADVGAVSGAKVIEKGDGALGESEGLYWRYESFVKKQESKLAGCTAVAGEVLAIRSDLFESPPDEIINDDTHMGMRIIARGFRIHYAPQARSHERVSQSAQDEIARRARIFAGRYQAITYARSLWPFRRPLALWQLLSHQTLRTLVAVNMVGALVMNILAVLSPSKAKSHKLLRLAAPFNWLLLIFQIVFYTMAWLGGRVDSNSKLGKVVYIPTFLVNSNWAGLIGLYRFVRRRQTTLWQRVGRRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F0</accession>
    <name>A9B5F0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ordered locus">Haur_0123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0123"/>
    <dbReference type="EnsemblBacteria" id="ABX02775">
        <property type="protein sequence ID" value="ABX02775"/>
        <property type="gene ID" value="Haur_0123"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0123"/>
    <dbReference type="eggNOG" id="COG0081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_0_0_0"/>
    <dbReference type="OMA" id="GWTDVDV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="25240" checksum="EAC4706B5E515530" modified="2008-01-15" version="1">MAKQHGKKYLAAAAKVEADRLYTPEEAAALVKETSFTNFDATVELHVRLGIDPRHADQTVRSTASLPHGTGKSVRVLVFAQGDTENIARNAGAEIVGGDELIQRIEKENFIDFDVAVATPDMMGKVGRLGRILGRRGLMPNPKSGTVVPPGDLPQAIKALQGGRVEFRNDKTGLLHVAIGKISFTPDQIRENLVVLLDAIKAAKPSGSKGVYIKSLTLTSTMGPGIPLDVNVAQATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G5</accession>
    <name>A9B5G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02790">
        <property type="protein sequence ID" value="ABX02790"/>
        <property type="gene ID" value="Haur_0138"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0138"/>
    <dbReference type="eggNOG" id="ENOG5032KGQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2436773_0_0_0"/>
    <dbReference type="OMA" id="QWCNDEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-141-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="90" mass="10748" checksum="84BBA20B64BA8D0A" modified="2008-01-15" version="1">MSQLSLDTSAKAEEIQINILRSMSIIEKLRLVEQLNQTRDRLAFYGLRKRFPHASNRELQRRFFDIKLDYELANKVYGSIEQWCNDEIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M3</accession>
    <name>A9B5M3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1613"/>
    <dbReference type="EnsemblBacteria" id="ABX04256">
        <property type="protein sequence ID" value="ABX04256"/>
        <property type="gene ID" value="Haur_1613"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1613"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_791886_0_0_0"/>
    <dbReference type="OMA" id="NGTAFDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1637-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732487" evidence="2">
        <location>
            <begin position="24"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39439" checksum="1B9B8C23A5376DA8" modified="2008-01-15" version="1">MLRRLRAYLVIVGLLVATVSAGSAETAAGQPRYFAETGHSLAYNFRLFWERNGGLPIFGYPITEVFVENGRPVQYFERARLEWHATIGWTLAGHLGHWAAEGSAKHPAFTPRSEAAYPGQIFFPESGHTLGGLFRQYWERNGGLQAFGYPLSEEFLERNQQDGQIYTVQYFERTRFEYHPELPAAFQVSLGHLGRQYLNATKAAPEWATRKVNNADAAWQALRPTRISIPRIGLDSTIVEAGFSLGTWDVPTDAAAHYWPVASFPTTAGNIVLAGHVGYHGIIFSQLPNAVVGDRLILTVDGVEHRYQVTDISTVTPDQTWVMEPTAEETVTLITCVPIGVYSHRLIVRAKPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B652</accession>
    <name>A9B652_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3627</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3627"/>
    <dbReference type="EnsemblBacteria" id="ABX06263">
        <property type="protein sequence ID" value="ABX06263"/>
        <property type="gene ID" value="Haur_3627"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3627"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="FNTLQMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3666-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="57"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="372"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="405"/>
            <end position="412"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="617" mass="68014" checksum="BD23EFA51AA873EA" modified="2008-01-15" version="1">MTTKALAPSRKRDDEIEKKVADLLPKDDENSLGKAYDPRLMRRLLAFIGPYKRTMTAAIVLMIIGTVLSVVSPWVIGQAIDVGIKAQSLDSLYTWTIIFAVVSLGEWLSNRSRIHLLAIVGTGVVADVRSALFRHLQRLSLNFYNRYSVGRLMSRLISDVDVLQDFVTWSITGLTRATFSLVGITIAMLLLNWKLALVTFAVLPIMVIVTNYWRVRVRQAYRSTRERIALINGYLNESISGIRVTKSFVREAANGEHFDDLNRSYFNANTSAARLAATFFPAVDFMGSLATALVVGVGGWLVLGDNLTPGVLVAFVLYVSRFFDPILELAQRYNTFQSTMASSERMFALLDTEPDMLDAPNAQALPAVRGHVMFDHVSFGYADGEPVLRDVTLEAQPGETIALVGETGAGKSTIIRLLGRFFDVTDGAVLVDGHDIREVTQASLRQQLGIVLQDTFLFGGSITENIRYGRLDASDDDVVAAAKAVGAHKFIERMPEGYATDVGENGVNLSVGQRQILSFARALLADPRLLILDEATSSVDTTTERQIQAALDTLMRGRTSFVIAHRLSTITNASKIVVLDRGQISEMGTHAELLARRGRYYNLYTMQWSKGNGTIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6E3</accession>
    <name>A9B6E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Capsular exopolysaccharide family</fullName>
            <ecNumber evidence="19">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">Haur_0194</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the etk/wzc family.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="19"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0194"/>
    <dbReference type="EnsemblBacteria" id="ABX02846">
        <property type="protein sequence ID" value="ABX02846"/>
        <property type="gene ID" value="Haur_0194"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0194"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009912_4_2_0"/>
    <dbReference type="OMA" id="TQVKYTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-197-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Wzz" evidence="17">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="18">
        <location>
            <begin position="345"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="532"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ABX02846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="575" mass="63527" checksum="4C941DC92ED57EDE" modified="2008-01-15" version="1">MNIIRRYITGLRRWLWLLVLGPVVAAGAAYGISSQQTPRYASSTRVIVGQTLKNSNPDYGSLVASERLVATYAQIAQSRTTMQAVEQRLNLSDMASSAIITTRPVQETEFLDIAVEANDPQQAADIANAIADQLILTSPAGPQSAEAKLLDEVNRQIATLNEEITRTDEEIKTLKAEIEQIGADKPAAESLIANLQLKQQSQNQNRQTLSTLYSTALGNRANSISVVEAATVNPTPIAPRPIRSAILAGILGFALVFGLALLIEYFDDSVQTPDEGVDLVNAPLLAAIVKQETKVTKASQRLVSRLDPRSPTAETFRTLRTNLQFSNVDTKARTLIVTSSQPEEGKSTVAANLAWVLAQAGQKVVLIDADLRKPMMHRVFEVSSEYGLTNLLTNNEDPTIRERTVLSVAENLWLIPSGPLPPNPSELLSSKRMEMLIWLLQQEYDWILFDTPPILTVTDPIALIPRVDGVVLVAEAKRTRRDMLAKCRAAVQTVGGRVIGLVFNKLDPRSEGYGVYYTYYYDQHHTSNRGRRFWNRKDDHQPVPSMSEPAPLDLHDPALDRSEAAYEMASHERSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F8</accession>
    <name>A9B6F8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0209"/>
    <dbReference type="EnsemblBacteria" id="ABX02861">
        <property type="protein sequence ID" value="ABX02861"/>
        <property type="gene ID" value="Haur_0209"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0209"/>
    <dbReference type="HOGENOM" id="CLU_1238797_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-212-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="25413" checksum="4C1CC6B7249AAD0E" modified="2008-01-15" version="1">MSESLPNLHVPAVQTLGERYSKLRLWWYMFAVLFVGDFFGLMAIVAINDLNDSVRSPVIWQLGMQRLSIVSIGVASLIFASFGWLIGWILRKVAICQVRWVVLAVFVGYWSAYILFNWPPSLLWLTNSPHTTYYRHMLSAMLTAIGCVAGPIALVMRPSSWAVVWLLSQLGLGFVIASISHWLVLNNFDGFAITFFIISILAIYPLVLSIWFSYYLRRQIVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P8</accession>
    <name>A9B6P8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04357">
        <property type="protein sequence ID" value="ABX04357"/>
        <property type="gene ID" value="Haur_1714"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1714"/>
    <dbReference type="HOGENOM" id="CLU_2409251_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1741-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10460" checksum="90DCB3C804E40D43" modified="2008-01-15" version="1">MTPEQEQRFNQLLAEIRDPYASLEGAIHELEHMIWTLQSQHTISNLRVRQAKVLIQIMQLTLRQQIPANLRLIQALCASEKSSSPAPLAKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R9</accession>
    <name>A9B6R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1735"/>
    <dbReference type="EnsemblBacteria" id="ABX04378">
        <property type="protein sequence ID" value="ABX04378"/>
        <property type="gene ID" value="Haur_1735"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1735"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_0_0"/>
    <dbReference type="OMA" id="MMSSWKL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1762-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="36161" checksum="220074853E7BC512" modified="2008-01-15" version="1">MAVTIAQPASQPKPKRRAAAALAIGLLVAFGLLLVIMTLSINFGAADVAPSTVWASLFDYDPSSTQHLIIRTLRMPRVLVAAIVGAILALAGAIMQGLTRNPLADAGLLGIESGAALGVVLAITFFDIKTLNLYSIFAFAGAAVTAVLVYSLGSLGRGGPTPLKLTLAGAMITAFCSSFTSAILILDQQTLDEVRLWLAGTVAGRDLGLIGQSLPYVVVGMILALSLGRSLTAMSLGEDVARGLGQRTGWVKTIAAIAVILLAGSAVALAGPIGFLGLLVPHIMRFIVGLDYRWLLPYCAIGGALLLVVADIIGRVIVRPMEVPVGVVTALLGGPMFIYLVRWRVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S6</accession>
    <name>A9B6S6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1742"/>
    <dbReference type="EnsemblBacteria" id="ABX04385">
        <property type="protein sequence ID" value="ABX04385"/>
        <property type="gene ID" value="Haur_1742"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1742"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_3_0_0"/>
    <dbReference type="OMA" id="MMVLWER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1769-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="16830" checksum="E0C3EE70589BCECC" modified="2008-01-15" version="1">MDLAEQGLLLEQQLCFDVYAASRAINKAYRPLLEALSLTYPQYLVMLVLWEHEAQTVKQLGEQLQLDSGTLSPLLKRLESAGFLQRQRRASDEREVEIQLTEAGRALRQQASNVPASIFQAIGLSAAEYLQLKHLLRQVMTSVEANYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6V5</accession>
    <name>A9B6V5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ParB-like partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3186"/>
    <dbReference type="EnsemblBacteria" id="ABX05823">
        <property type="protein sequence ID" value="ABX05823"/>
        <property type="gene ID" value="Haur_3186"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3186"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773481_0_0_0"/>
    <dbReference type="OMA" id="LWIDPRA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="350" mass="39020" checksum="85F75CAE01A7AA98" modified="2008-01-15" version="1">MQLLYLSLDQLEADPSGIRQDQGDIAALAATIAEQGLLQPLGVIGIGADRYRVVYGGRRLAAISSLGYERVPCIKLDLQEADRLTQQLAENVARLDLNDLEKAVAFKRLRDQLNEVGVNGDLDEEVGKRVGLVGRSVRRYLSLLDLPEEVQALLRNGDLNVTQAQHIRRLPNERRQVELARYAADEGMSAAQISGLAAYLTANPELSVEAALDALEGGLELRTERIGEVEQTGGRLSHGSTEGAGLDPDDADIWDDEDERIQHEHDQFFAVVEETEAKKNKSRVFRIRSLDQMVDETDRISRAVHEGDFSKWLESDENAPFKVRLVLKQIETLSKALRSTLQDQGWENEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B703</accession>
    <name>A9B703_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3234"/>
    <dbReference type="EnsemblBacteria" id="ABX05871">
        <property type="protein sequence ID" value="ABX05871"/>
        <property type="gene ID" value="Haur_3234"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3234"/>
    <dbReference type="eggNOG" id="ENOG5031RMA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091313_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3269-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025324">
        <property type="entry name" value="DUF4230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14014">
        <property type="entry name" value="DUF4230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="28881" checksum="0A3E08E141E7AF2B" modified="2008-01-15" version="1">MYRQRNSGCMSSLFFLLIGALGIMVVLSITGMFDPIGMWFRQPEAVNNAQGPAIVQQLRARDEWITFSYQADQLIEARKEGNFFQELLYGDRILLQARGEVAAGIDMSQLSDDQIEIDGKSIKITLPPARIIYSRLDNQSTRVYDREQGWLSRGDINLESDARTFAEQSIITSACESGVLDRAAVEAQKNVSDLLYAVDYTNVTVIVSKVGDCAGSANQMATQQPNAIEPTAPANVPTNSTAQPSVAPTPTNSGGSLSGTAVPIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B765</accession>
    <name>A9B765_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3712"/>
    <dbReference type="EnsemblBacteria" id="ABX06348">
        <property type="protein sequence ID" value="ABX06348"/>
        <property type="gene ID" value="Haur_3712"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3712"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056919_0_0_0"/>
    <dbReference type="OMA" id="HCRSYIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3754-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="26"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="404" mass="45569" checksum="11E206FE9FF7879C" modified="2008-01-15" version="1">MLKTLYITYDGLLDPLGQTQILPYLEGLAAQHGHQFVILSFEKAARWADLARRQALIERLQSHGLVWLPLRYHQRPILPATLYDLALGLWTASVAVWRYRIQALHIRSTVPMTIALLLKRWFKLPLLFDLRGFWADERADLGMPRIGLVYRLLKKLERASLQQAEQIVTLTQQSLPYLAEHSQTPHIANKTTIIPCSANLQVWQRDLAARTQIRQALGWQTNPILVYSGSLGGGYRSRDMAECFASWLHAEPDLRWLVLSNQDPQPLITALQDLNVPAESYTIRGVASNEVAQWLSVADAALSLITPSYAKIASSPTKFGEYLACGLPIFSNAGIGDSDQLFAQGVAIKLDDFNVAAYQAAWQTYQALREQPDLAQRCRALAEREFDLQLAVERYAACYRELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7G1</accession>
    <name>A9B7G1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisI protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0282"/>
    <dbReference type="EnsemblBacteria" id="ABX02934">
        <property type="protein sequence ID" value="ABX02934"/>
        <property type="gene ID" value="Haur_0282"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0282"/>
    <dbReference type="eggNOG" id="ENOG5030CJG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149829_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-285-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014968">
        <property type="entry name" value="XisI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035943">
        <property type="entry name" value="XisI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08869">
        <property type="entry name" value="XisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143847">
        <property type="entry name" value="SSF143847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="103" mass="11561" checksum="D6E45801C1E2A564" modified="2008-01-15" version="1">MVACSTTTIIETVLIATLCPDTTGTCAVQTVFDREQQHYMVVVAGWHGQHRIHRCLVHIAYHDERVWIHCDHTIHGIPERLIAAGIPATRILQVFPLAGLRMP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I9</accession>
    <name>PTH_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name type="ordered locus">Haur_0310</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B7I9"/>
    <dbReference type="SMR" id="A9B7I9"/>
    <dbReference type="STRING" id="316274.Haur_0310"/>
    <dbReference type="EnsemblBacteria" id="ABX02962">
        <property type="protein sequence ID" value="ABX02962"/>
        <property type="gene ID" value="Haur_0310"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0310"/>
    <dbReference type="eggNOG" id="COG0193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_4_1_0"/>
    <dbReference type="OMA" id="HVLSKFH"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000092949" description="Peptidyl-tRNA hydrolase">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="206" mass="22784" checksum="D617E3544F7C4E65" modified="2008-01-15" version="1">MFLIVGLGNPGEKYLNNRHNVGFQCVAEFARRHHLSFDGKRSDARIAEGLVNGQRVALARPQTFMNDSGKSVVGLVNWYKIDPASELLVVYDDLDLPFGTIKLRNQGSSGGQRGMNSIIQLLGTQKFARLRFGIGRPPEGWEVINFVLGNWNAAERETLPKLYDRAVEACELCLSDGVTKAMNAVNGEAPKKSKDQAKEPANEQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K0</accession>
    <name>A9B7K0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0321"/>
    <dbReference type="EnsemblBacteria" id="ABX02973">
        <property type="protein sequence ID" value="ABX02973"/>
        <property type="gene ID" value="Haur_0321"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0321"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046685_6_0_0"/>
    <dbReference type="OMA" id="CHIGAFS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-324-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="43369" checksum="26F7353AC517D34A" modified="2008-01-15" version="1">MQPQARFSYLVLSFGTRLLLSCIFTASMLYRIQVLQLDPLQLVLVGTMLEAAAFALEIPTGVVADVYSRRLSVVLGVAFLGLGALSEVWLGSFVGSLLAQVVWALGYTLMSGATEAWITDELGVEVVEALFLKAAQLNSIASLLGIGLGVALATIGLVWPIVGGGLALVGLAISIRWFMPETQFSPAPAAERQSWGRFGATLGHGWQAVRGQPVLLSIMVMSAIAGAASEGYDRLWEAHLLNNIGLPTWLDLQPVSWFGAIAALGTLASLVAVIVIKRLASNTTERSIWLLRWQYGLLAAGLLGLALTQQFAIALFWIMLIRMLRQSIQPLYSAWLNRLIESRSRATIISINSQADAFGQILGGPIIGLIASRMGLPAAFVAASCCLWPMLVLLRQRQLNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R1</accession>
    <name>A9B7R1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Undecaprenyl-phosphate galactose phosphotransferase</fullName>
            <ecNumber evidence="9">2.7.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.6" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1796"/>
    <dbReference type="EnsemblBacteria" id="ABX04439">
        <property type="protein sequence ID" value="ABX04439"/>
        <property type="gene ID" value="Haur_1796"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1796"/>
    <dbReference type="eggNOG" id="COG1086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024920_0_1_0"/>
    <dbReference type="OMA" id="NWSVLFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1824-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047360">
        <property type="term" value="F:undecaprenyl-phosphate galactose phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017473">
        <property type="entry name" value="Undecaprenyl-P_gluc_Ptfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03023">
        <property type="entry name" value="WcaJ_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="292"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="478" mass="53647" checksum="C9F20F16E5284A12" modified="2008-01-15" version="1">MATTTMLNQTTVVTRRYRYVVLLLLMGCDIIGVNGGFFLAYYLNLEAIVREFQPPSVGQVLLTLAVLNALFGTLFTANGLYRMQRGGSRIDEGYHIFRAISIGTIMFIALNTLFPIINITTLTLVYGWILATIGTTILRLIYHRAIGQLRLRGYDTRRVLIIGAGEIGQLVYRQMSKAPSLGYQIIGFLSDDVPTGQQVVDDVPVLGKRAKLGLAVRTCAIDEVIIALSGASYNDVFALISQVEDESVSIKIYPDAFQLITNNEVSVGELSGLPLITVRAVPLDRQLNRTVKRLLDIAVSAAALVMLAPLLLLIGILIKIDSPGPAFFIQERVGRDGRPFKMIKYRSMRLDAEKLGTWTTPNDDRRTRLGTFLRRFSIDELPQFINVLLGDMSVVGPRPEQPRYVAQFSEQIPRYMHRHREKAGITGWAQVNGLRGDTSIEERTRYDLYYIENWSPMFDIKIIIRTAYNAIRGDENAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U6</accession>
    <name>A9B7U6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein typical subtype</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1831"/>
    <dbReference type="EnsemblBacteria" id="ABX04474">
        <property type="protein sequence ID" value="ABX04474"/>
        <property type="gene ID" value="Haur_1831"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1831"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_535033_0_0_0"/>
    <dbReference type="OMA" id="CLWPGVR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1859-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="509" mass="58326" checksum="E97A56DD0B745442" modified="2008-01-15" version="1">MTEDFLRYNDWPLVLATARDEQWTNLLLSCCPLETNPELLNLLGQCHSLNSLGLFQCKLTEVPTVLRQLPLKVLSLSCNNLRQLPDWLIELPLVELSLFGCPHVELPANFDQSSIEILDLSSNEMTELPAIVRRMPKLKQLLLRENHFQSIPRLIADTAIERLDLAENPIRDFRLLPATRLRILNLSNTGLTMLPIELRQHPLQELDLSRLDDLHIPPWFAELSSLRILNLFYSNFSEPELHLPTNLAAVWMQHCNLTSIPQAIQSNPQLRSLNLSENNFADAELVVNGPCEFINLSESSLGELILADHALSSLKSLDLQMANVKQVRNLAKCRNLGGLRCVDAYLLAMPTTPEWLKSLRYLWLNGDFSNEHIPSWFWQLEQLQSLHLQSPDWTLLDPRIGQLSELQDLSIYSTRFEHVPISLLQLTKLHRLQLHLADPSHFNWLASLPALHELGSYPYGQKPPLAIQARAADADFRYHNQFAESNDDDGLYPHADLAWLDRYFPQNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D4</accession>
    <name>A9B8D4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ntox44 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3851"/>
    <dbReference type="EnsemblBacteria" id="ABX06487">
        <property type="protein sequence ID" value="ABX06487"/>
        <property type="gene ID" value="Haur_3851"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3851"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808403_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3894-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028946">
        <property type="entry name" value="Ntox44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15607">
        <property type="entry name" value="Ntox44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ntox44" evidence="2">
        <location>
            <begin position="197"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="36829" checksum="28896D1CFBC13A7B" modified="2008-01-15" version="1">MTAEIVQAQFEQLEQIASRFNRQAEQSESITQSIRQVHDALVGGQWQGDAAKAFANEMQSNVFPAFRRLTAALRESQAVTLQIKNLMRQAEEEAARLFQGPLTEGDAAAKPAGGQPNSNTTQFTAEETPTPTPPADPNNYDRFDQTLQYMHQEMITNAQSETVGMIKSLLDSFRNPQWYDYLGGGNPGDKLIAALAMWAAKVHSGGDWDHKPKLNDLLDLDGDPSTNADNDFYFPIRGDQTNEYYYDIWSNIHYGYVGAAAGFDTSTLQDGANLGDAFTGTNDPGDVLTVQIGIDLWNKYGSSMTPEQLHAEILAHRDELVNLDKTTSGKNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G6</accession>
    <name>A9B8G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_5000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07630">
        <property type="protein sequence ID" value="ABX07630"/>
        <property type="gene ID" value="Haur_5000"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5000"/>
    <dbReference type="HOGENOM" id="CLU_073529_0_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5063-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="79"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="204" mass="22410" checksum="DD9DB538C525A175" modified="2008-01-15" version="1">MAIDAIPTLLALFNPSRPTARDQACAAALWQAADQSWNTLARMSEEELTPLVGRAHAIRLRTAFAIGHAKLAEAVTGEPITTPMQVVALLQAEMSHLEQEELRVISLSTQAHIIGMHTVVVGTLNTAYCRMADLFREPLRRNAASVILAHNHPSGMVWASPEDILLTKQAIQAGQLLEIELLDHLIIGKGGYTSMRERRLAWSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P7</accession>
    <name>A9B8P7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRISPR-associated exonuclease Cas4</fullName>
            <ecNumber evidence="6">3.1.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_5083</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="8 9">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="9">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8 9">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+) or Mn(2+) required for ssDNA cleavage activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CRISPR-associated exonuclease Cas4 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.12.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07711">
        <property type="protein sequence ID" value="ABX07711"/>
        <property type="gene ID" value="Haur_5083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5083"/>
    <dbReference type="HOGENOM" id="CLU_102055_2_0_0"/>
    <dbReference type="OMA" id="CCYRNIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5145-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013343">
        <property type="entry name" value="CRISPR-assoc_prot_Cas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00372">
        <property type="entry name" value="cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0614">Plasmid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="7">
        <location>
            <begin position="12"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="197" mass="23383" checksum="88EDE4937099C90C" modified="2008-01-15" version="1">MTTNEPNYFLEVTDIKQARICPRVVFYRYCLPRIRPITGKMELGIERHREEVGREERRSLRSYGLTTGERHFDMLLRSERYRLVGMLDLIIMTETECIPIEYKLSERMPGSHVKAQLAAYALLVMEQWQKPVRRAFSYLLPLRKAIEIPLGQRQLNDVQRSIEHIHQMIVHETMPEPPKHQAICVNCEFRRFCNDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P8</accession>
    <name>A9B8P8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_C25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07712">
        <property type="protein sequence ID" value="ABX07712"/>
        <property type="gene ID" value="Haur_5084"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5084"/>
    <dbReference type="HOGENOM" id="CLU_2395693_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5146-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C25" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="93" mass="9678" checksum="D6A78426A1631F5C" modified="2008-01-15" version="1">MLHPDGGALATWGSSGLEVAHGHDHLQHGLVTAALTTARPTLGQLTEAGVLELALTGQCCTDALRTTLLLGNPAPVLRVVPVPQRVWVSVVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W7</accession>
    <name>A9B8W7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07781">
        <property type="protein sequence ID" value="ABX07781"/>
        <property type="gene ID" value="Haur_5153"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5153"/>
    <dbReference type="HOGENOM" id="CLU_1088918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5215-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="28894" checksum="C1A3A0F733E47690" modified="2008-01-15" version="1">MDKPYLIEQIGRAAFQRACTQARNAAPAMGTRTQSQSYHSPLPQWIDRMIWEQADGLTTAQRLRLSVSMYRDLPCYGVLLGLMCRYQGLDRVHQKLYWFEVCRMLSHGDPAWSGPIEYHLALDWFERNDDGATIWQTLRRAANPALLRSLLRSSGPAAWSLKMALYRELLADPAWHAAIYASVLASYGGVYGQIDRVEALTVLHHLILPHRDDAEWRSMLTVLGHGDRYTNGFGVKAFHAPQQDDEGSGDQAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X8</accession>
    <name>A9B8X8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07792">
        <property type="protein sequence ID" value="ABX07792"/>
        <property type="gene ID" value="Haur_5164"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5164"/>
    <dbReference type="HOGENOM" id="CLU_038153_1_0_0"/>
    <dbReference type="OMA" id="GHVLRCE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5226-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="374" mass="41976" checksum="869053E1E730296B" modified="2008-01-15" version="1">MISLNAIIQRFGASYRTHCHGRLSVQQRRVISAIAACRTETLGGQVFTCPTCQTTRYSYHSCRNRHCPTCQQDAGAAWLADQQALLLPVPYFLVTFTVPAELRPIALTNQALLYAAMFRASAAALQQLAADPRHLGGQLGMLGIFQTWTRDLRYHPHIHYLIPGVGRTTDERIVFPPAPDFLLPVRPLAMIFRAKLRAALRQTAIAATIPSTAWEHDWVIDCRPVGTGETALKYLAPYIFRVAMSNNRIVSADETQVTFRYRHSASGENRTSTLPVETFLDRFVAHILPKGFVKVRYYGFFRTGVRASLRRIRAQLMLFRSHDLLDRAIPQPKLSAQTHQLSTCPACGSLMHGRQIVSSRTRAPPHGMHHPRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B903</accession>
    <name>A9B903_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Resolvase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_5190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="8 9">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="9">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8 9">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07817">
        <property type="protein sequence ID" value="ABX07817"/>
        <property type="gene ID" value="Haur_5190"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5190"/>
    <dbReference type="HOGENOM" id="CLU_010686_8_0_0"/>
    <dbReference type="OMA" id="QRQMEGI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5252-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0229">DNA integration</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0614">Plasmid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="7">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="5 6">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20824" checksum="CD6272AB0F267EE5" modified="2008-01-15" version="1">MQLGYARVSTDDQHLHLQHDALQQAGCEQIFADHGSGATADRSGFRSLLAYARAGDIVVVWRLDRLSRSLKDLIEIVTLLDTKGIGLKSLHESIDTTSSAGKLIFHIFGALAEFERTLIRERTHAGLQAARARGRKGGRPKALSADQQALAVKLYNEKQHTIAQICRMLGISKPTLYNYLADASAAGTTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B924</accession>
    <name>A9B924_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07838">
        <property type="protein sequence ID" value="ABX07838"/>
        <property type="gene ID" value="Haur_5211"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5211"/>
    <dbReference type="HOGENOM" id="CLU_160607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5273-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14034" checksum="538757B3FFED8CF5" modified="2008-01-15" version="1">MLGLSIILNTELQKRGWRRSTLAAQSGVSEPTLSRIMNDAASIPELKTMAALSKALELPLRRLLEACGFDLDTTTPLDDLQRVHLLMTAVPELHTFLAPLAQLSPADRQSVITFAEMLAHKRSTTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B941</accession>
    <name>A9B941_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07855">
        <property type="protein sequence ID" value="ABX07855"/>
        <property type="gene ID" value="Haur_5228"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5228"/>
    <dbReference type="HOGENOM" id="CLU_119902_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5290-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017101">
        <property type="entry name" value="P-loop_ATP/GTP-bd_All4644_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037081">
        <property type="entry name" value="P-loop_All4644_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="15671" checksum="A46497FC613513A6" modified="2008-01-15" version="1">MMFCETPSLTLLAGLPGSGKSTLAKRLAALGATIVSLDAIRAELGDVTDQSRNADVVAIAHMRVEAALLSGQWVVLDATNLRRAWRQRWERLAAELHVPIRIHWVRTPLLLCLWRNWRRTRRVPVRVIVRMWRETED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A4</accession>
    <name>A9B9A4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5291"/>
    <dbReference type="EnsemblBacteria" id="ABX07918">
        <property type="protein sequence ID" value="ABX07918"/>
        <property type="gene ID" value="Haur_5291"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5291"/>
    <dbReference type="HOGENOM" id="CLU_1254505_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5353-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="24895" checksum="D79A71D21F2DD002" modified="2008-01-15" version="1">MNLLQRILMSIRGMFDMNKPSTKTPFNINQDFAHIGTNYIGERITVNISSQQFVMDAEDSLTLAAGLLISLTSDTEQLTSNFISYVSRVNNGEDKSGIRKLIVKDIDTFSRSIRNINDEFGKLMHNFSHLFIHQAIIKGDLNKDTKYLIKHQIQETSIKFDRAINAINGVVKSLNNATNQYSKAGLETIIIDNCIDNVKKLLVIMVEVKGRFDILALKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9B0</accession>
    <name>A9B9B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5297"/>
    <dbReference type="EnsemblBacteria" id="ABX07924">
        <property type="protein sequence ID" value="ABX07924"/>
        <property type="gene ID" value="Haur_5297"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5297"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_578436_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5359-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsK" evidence="2">
        <location>
            <begin position="109"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="128"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="500" mass="53251" checksum="EE5BBAF29C659D55" modified="2008-01-15" version="1">METMIFLLFVAGMLVAGVKYRRMMLLVADLRADLATAKAMLAKATVEQPKPKPTHSSYPDVTPTYIDYTPLAGAGKALAKPPSDLRTTLQHLAKIVKGEKYCFPLGWASDGLYSGCFVGDVNHILISGMSNAGKDNAVTGMLLSLALNHSPKDLQIGLIDGKGLDWLGWSNKAHTWMLADEPEKIAAAMARLTEERRRRRGILAAAQCASWDEYQGGDLPLLVVFISELSLLEDATKARELGAWLNSELSAGRAFGIRYIIGTQNASNFDTRWRGQISLFMAGFQPSRSADEPNTGMGTSDLDAIGAIAPSKLIAPPEGAGVFTVVHAPKAATIRVPFLTSQHRKWLLDQLPDAPKKALHHPQSSAVSSRAGSTTQPALDPMLAALLNGEPLLAESSTASSTVLARDNGIKPVFSSTLPSSSTQPILSVSGIPPVALPAIEGIDPDEVQKIVEAAPNYSSRRALCQALFGLSGGAPYNKVKLVCDALGLLNGNQPLQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE3</accession>
    <name>A9AUE3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0411"/>
    <dbReference type="EnsemblBacteria" id="ABX03062">
        <property type="protein sequence ID" value="ABX03062"/>
        <property type="gene ID" value="Haur_0411"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0411"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2584927_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-414-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="8851" checksum="EDA88AE122FB7587" modified="2008-01-15" version="1">MATILLADEVFAVVGAAIEVHRELGSGFLEAVYQEALALELAQRQIQFAAQTPLAIRYKQQLLQKPILLILFVTTKLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM6</accession>
    <name>A9AUM6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04553">
        <property type="protein sequence ID" value="ABX04553"/>
        <property type="gene ID" value="Haur_1910"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1910"/>
    <dbReference type="HOGENOM" id="CLU_1616760_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1939-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732150" evidence="1">
        <location>
            <begin position="23"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="17818" checksum="32125806C54D91D1" modified="2008-01-15" version="1">MRTFVVYLLFCLLVGCGQPDQVATTQPTLGLILSNPTATPVAISPSAAPASGAINPTQAVASTPSISADDWQSQYRAWIEEARQTHPYSESSEVMWNVMICESSGNPTIQGPGGLTGLFQYQPSTWAGTWNPYRDQPITDARAQIFATAKAWHDGNQQWWGVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN5</accession>
    <name>A9AUN5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1919"/>
    <dbReference type="EnsemblBacteria" id="ABX04562">
        <property type="protein sequence ID" value="ABX04562"/>
        <property type="gene ID" value="Haur_1919"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1919"/>
    <dbReference type="eggNOG" id="ENOG503281V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1276197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1948-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023815">
        <property type="entry name" value="CRISPR-assoc_A791736"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03984">
        <property type="entry name" value="TIGR03984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="216" mass="24791" checksum="8E289B4F4AAEE92F" modified="2008-01-15" version="1">MKSLSEIIQHFIPDQASTIQGLTFKWLLAFAIDGVIWGKFDADRLIMYEKSDLQGYNEAIQASYTPFRSETLQQMLIFGEQAQLSIWRDDDQWGSHIIRDSANIIDETQILWGTHAEAVGDWTFLTDGNQGMHHLIPLDLATCNAQKSNGVAYQIEQKPNGQRQFKAKLQFERTEADWRPAQLVLHHSIEFDEHGIATIRASRYVDLRWQTQGAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP4</accession>
    <name>A9AUP4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1928"/>
    <dbReference type="EnsemblBacteria" id="ABX04571">
        <property type="protein sequence ID" value="ABX04571"/>
        <property type="gene ID" value="Haur_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1928"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329222_0_0_0"/>
    <dbReference type="OMA" id="WYENNGS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1957-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731644" evidence="4">
        <location>
            <begin position="29"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="872" mass="89956" checksum="BB9B1FBB0E09C80F" modified="2008-01-15" version="1">MPISLKILSSLLMAALLITIMQHPKAQAVPAATIVFDPVVTYPTTGSGAFVATGDFNRDGVADLAATSRATNEINVLLGNSDGTFAATVAYATGNFPISVAVSDVNHDGNDDLAVVNFGSASVSLLLGTGTGSFNAAVNLATVGAPESIQIADLNRDGHPDLVVGGLTATNNVGVALGNGSGGFASPLLSTVGGGGYGLTVADFNHDNRMDVAKTIYTDKAFTVGFGNGAGGFTGAVNYPLSDLPYGIVPGDWNHDGNRDLAIVIRPPTNQVAVVFGSANGSFGAPTYYPVGPTPEWLTASDLDNDGNQDLAVATISGNVWVLQGSSNGIFHDAGSFSGAFVPRAVAAADFNRDGRNDLTTSNEGAIVGVLLNRSDSQCGGIGFSATTTAIGAETLVGSTTSDMNNDGDLDLVIANPSTNSIIIRYDNGTGSFSSAISISLGLQPSDVAVGDVNRDGRNDLIVAAFLANQALVLLNNGAGNFTPTSYPTPFNPVEITIADFNNDGSPDFASANYNANSISVRMGNGSGAFGAATDYASDAHPFKLTSIDLDRDGAIDLAWVNYVANTLSVRLNNGNGTFGSTINTAVGVGPTSVNFGDWNRDGIADAAVTNRSAHTLSILRGTGTGAFSVTATMPSNLLPMDVLSHDFNLDGRLDLAVSYTSESSVTIARGNGDGTFAALSAFGPRVANRGLSAGDFNHDGKIDLAGANYLSNTLAVLLNSCPAAPPPTPTPTITPTPSASSQRSAYLPLVSLRQISVLATLNDQAIPIRPITVQGETYYTTTIQLVTSLPPGGKFYFSASPQSVQPIQVDDELVVRINGQVQFSQIATTPMIVEIPRATLETWVGQSLEIAFRDVYGSLVGSSPVWLIWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUZ7</accession>
    <name>A9AUZ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tn7-like transposition protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3953"/>
    <dbReference type="EnsemblBacteria" id="ABX06585">
        <property type="protein sequence ID" value="ABX06585"/>
        <property type="gene ID" value="Haur_3953"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3953"/>
    <dbReference type="eggNOG" id="COG3677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033785_1_0_0"/>
    <dbReference type="OMA" id="YGELYWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3995-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009492">
        <property type="entry name" value="TniQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032750">
        <property type="entry name" value="TnsD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06527">
        <property type="entry name" value="TniQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15978">
        <property type="entry name" value="TnsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TnsD" evidence="1">
        <location>
            <begin position="177"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="597" mass="68419" checksum="27EE51C70A9CDFB1" modified="2008-01-15" version="1">MRFASANIAVEELFGTRNIVAVVDLPSRLDILSNRLPKALGLNSELLISNHTSLPLFAPFLSGDALHRVRRSMLGNKGGTVHSRIGIMASGVKSLRKLRFCPVCVNEDRSKYGECYWHRVHNIAGINVCAHHGCILQDSILSFQRQSTYYAYNAAEDYIPEIEFADPTPANLHLYALAKQAYWLLNNISNADLKDMYNVYRRCLDLRGLTTASNSIRQQQLQSTFIDFYTPELLDTISCSLEDVHQTWLSRLVGGDYVAHHPLRHLLVLHFFGHTPESALKSLDEPTPDPFGHGPWPCLNRVCPHSHKDVIETCNVRRSRYTRDRPIGTFACPFCGFSYIRTGPDQSQNSRYHISKIQEFGFIWEKRLVELFAQQILSLRAISKILGVDPNTVKRHAQRLMDTGDKTLNKDLSNTNASLDATDLLISHRHTWLKAIKVFPQFGVSQLRKRFSTAYAWLYRNDKAWLFLHTPARSSRIFRTNRVSWPARDKLLLQAVQEAATRILNQEQWPKQMTLGAIGREAACLPILQRHLDKLPKTADRLKDLVETREAWAVRRLQWTINQAQNQGLILKGWEIVQRSGLGRFPKKWFEHHGIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV24</accession>
    <name>A9AV24_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3980"/>
    <dbReference type="EnsemblBacteria" id="ABX06612">
        <property type="protein sequence ID" value="ABX06612"/>
        <property type="gene ID" value="Haur_3980"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3980"/>
    <dbReference type="HOGENOM" id="CLU_2069882_0_0_0"/>
    <dbReference type="OMA" id="RTINGMK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4022-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="13386" checksum="41280A9CCAFA6124" modified="2008-01-15" version="1">MWQVVVPQRHGRPCGRPLQLSGDRSYDARRIVHWLQQYGIRSVIPPRRRCGMRKAGPVGYDAAAYRALNVVEGTIVCLKECRSVATWFEKLALNDRGFVHLAMIQRVVRILAPSTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV38</accession>
    <name>A9AV38_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="4" type="ordered locus">Haur_0465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0465"/>
    <dbReference type="EnsemblBacteria" id="ABX03116">
        <property type="protein sequence ID" value="ABX03116"/>
        <property type="gene ID" value="Haur_0465"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0465"/>
    <dbReference type="eggNOG" id="COG0682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013386_1_2_0"/>
    <dbReference type="OMA" id="FRLNPLW"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="33062" checksum="3C6FF9D92D5B0584" modified="2008-01-15" version="1">MHPPFGPNLLELGPIVIRMYAIAILSGAMLGGWLGAHRARARGYNPNIVWDWLIVGLILGVAGGRIWYVASSWPQYRDGPFIDMINTTKGGLAIHGAIVGAVLTVIIAAWRTKTNALTWMDVLAPCLSVGQAIGRWGNFFNNEAYGGPVSNGLPWNLDIPAQYRIRGTEQYDASTRFHPTFLYESLWNLGVLFSIVFIERRFRGRLRNGDSLLIYGVLYSIGRFWIEDLRVDKLCTGGVGGAICNDSLSTARLTSIVLIVGCSALFVLRRVLQRNPPASSYQQWDEPWQPEPETAKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV96</accession>
    <name>A9AV96_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0526"/>
    <dbReference type="EnsemblBacteria" id="ABX03174">
        <property type="protein sequence ID" value="ABX03174"/>
        <property type="gene ID" value="Haur_0526"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0526"/>
    <dbReference type="HOGENOM" id="CLU_2130035_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-535-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12321" checksum="4BC721D58D72B07F" modified="2008-01-15" version="1">MLYTILTAIIAGLACAVLMVAIHGLLWHRHWRLSRPQAYTVGTACIGIVLTIWALLLNQPATIIGFWAIAGLAGSADLVAWWIRSRLQRIETEAEAAGFIRGQIVGLDNDGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC3</accession>
    <name>A9AVC3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1971"/>
    <dbReference type="EnsemblBacteria" id="ABX04614">
        <property type="protein sequence ID" value="ABX04614"/>
        <property type="gene ID" value="Haur_1971"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1971"/>
    <dbReference type="eggNOG" id="ENOG503319U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1452586_0_0_0"/>
    <dbReference type="OMA" id="HLHPARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2000-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="21282" checksum="D88DF62CC5608E57" modified="2008-01-15" version="1">MLLQTSLNCWKHHARWVLQALTTLQPDDQPRLLHALQTIGNSQMDLYLGDLDPVAIDSQIIAQLQQRGIAAPTHYAEWLASNGHYQLLQLDDHSEWVLRWGEIDQQRVHLHPARYSPLSVRVRAPVLRSAYAIMVWQGWYGGDLFDLQLINRVRTAWLHLSPIAKLPPNDGLAALLSLLRELNQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF9</accession>
    <name>A9AVF9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2007</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2007"/>
    <dbReference type="EnsemblBacteria" id="ABX04650">
        <property type="protein sequence ID" value="ABX04650"/>
        <property type="gene ID" value="Haur_2007"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2007"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_0_0_0"/>
    <dbReference type="OMA" id="TVGWCAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2036-MON"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="427" mass="48331" checksum="CAD467F17921EB3D" modified="2008-01-15" version="1">MTNSLTITDNRTGKTYELPIVDGTIRALDLRQIKADAEDFGLMTHDPGFNNTSSCRSSITYIDGDAGILRYRGYPIEQLADSSSYLETAYLILNGELPTKPQLDAWVHEITHRTMVHENIKKLMDGFHFDAHPMGMLISTLSAMSTFYPQAKNVKDPAMRRLQIARLIAKVPTISAYAYRKRMGLPYVYPDNSLSYTGNFLKMMFQRADPYIPDPIMEKALDVLFVLHADHEQNCGTNAMRSVGSSNVDPYSAMAGAAAALYGPLHGGANEQVLRMLQEIGSASNVADYIRRVKNREVLLMGFGHRVYKNYDPRAAIVKQLAYDVFEVVGRNPMIDIALELEKIALEDDYFVSRKLYPNVDFYTGIIYQAMKFPVDMFPVLFAIPRTVGWLAQWDEMHNDKETSIARPRQIYTGYDARDFVPVEKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR5</accession>
    <name>A9AVR5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4033"/>
    <dbReference type="EnsemblBacteria" id="ABX06665">
        <property type="protein sequence ID" value="ABX06665"/>
        <property type="gene ID" value="Haur_4033"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4033"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_12_3_0"/>
    <dbReference type="OMA" id="FQEWAKA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4076-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735254" evidence="4">
        <location>
            <begin position="21"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="47449" checksum="F0FA8EAD2F9FFB50" modified="2008-01-15" version="1">MVRKWRWKFALVSLLTTVLAACGGGSATQAPTTNPNRVTLTIESWRSDDQKVWTEQIIPLFEKSHPDIHVEFRPTAPTEYNAALNSKLEAGTAGDLITCRPFDVSLGLYTAGHLTALDDLPGIAHFSDVAKSAWQTDDGKTLFCLPMASVIHGFIYNKAIFNELGLTEPKTVDEFFAVLDKIKQDGRYTPLVMGTAEQWEAATMGFQNIGPNYWFGENGRKALIDGSAKLSDAAYVSTLKDLARWGDYLPDGFEAVKYADAQMLFASGKGAIYPAGSWDISYFNQNAKFELGAFKAPVAKANDQCFISDHTDIGIGINAKTAHMAQARTFLEWMTGPEFAGEFSNALPGFFSLSDYPVSLKNPLAQTFVDWRKQCQSTIRNSYQILSRGEPNLENELWRISVGVIDGTFAPEDAAQDLQKGLDNWYKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV8</accession>
    <name>A9AVV8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0548"/>
    <dbReference type="EnsemblBacteria" id="ABX03196">
        <property type="protein sequence ID" value="ABX03196"/>
        <property type="gene ID" value="Haur_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0548"/>
    <dbReference type="HOGENOM" id="CLU_596866_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-557-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="458" mass="48865" checksum="FE89FA24F4D2FA02" modified="2008-01-15" version="1">MTTMQLLRNGSVVIDFMPAGVNPTEGTTCYWLVDGSWQPQVPQRDRRLISNGEQFQPSVQSFAVNIFGGTNEDQAWAAYHALMVLLDDAERFYEEGYSSAVVWRTKPSDNTVHSDMLVMGRAGDTPMVGTSPTLIQDNDVWWILNVPVMFLCRPLRCATASTNSSTSASANIANIHQPNFSGSAAPLESPTNLTLNVAAATNGTTINGLIAVAPRGKMVKSAAWLFAPSPTQFGWSRQIQASGVYATDNLLCFYNFPSVTPSYSPNGVLTDIGPLNSRSIIQWAMLKTTAPFLITPVVRSNGALIEGRATLVDSATPIIVPLGQTSAPYLITGHQLKLTNLTNAGAIYINAILTIAADAGGWSVIPFASLPLPSTATTITVDARYLSNPDASLTWTNAGVTQAVPTDSNPLALTKDLQLDVNLFAVNGNAWSATTENAASARTMTVQASRLNGAIIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW31</accession>
    <name>A9AW31_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0621"/>
    <dbReference type="EnsemblBacteria" id="ABX03269">
        <property type="protein sequence ID" value="ABX03269"/>
        <property type="gene ID" value="Haur_0621"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0621"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952762_0_0_0"/>
    <dbReference type="OMA" id="EWFGFRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-630-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="158"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="32891" checksum="49B3B258F1E4D626" modified="2008-01-15" version="1">MHLFRRVPSIHDLAMRPLVESDLPPLMGLLEQTPWASLSIPHDEFRLTLNDQLSIVLEYNGKLWGCVLMGYAVGPIAWIRALIVHHSLRPAEAVTEFLHAAEGYAKAHGVERLLIMSDERDASWLLPWVLREGYQPQLDVVGYEKRAMNIPAWGNTGAWIRPATTDDVPMIAKIDAAAFADEWVKNSTILAGVFPVAPFYIVAELNQTIVGYAFATVHHGGMMAHLVRIAVDPALQGQAIGVRLLAELVDWCSLNGVQLLSLNTQNTNQHAQRLYEWFGFMRNGERQTVLVKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF0</accession>
    <name>A9AWF0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4077"/>
    <dbReference type="EnsemblBacteria" id="ABX06709">
        <property type="protein sequence ID" value="ABX06709"/>
        <property type="gene ID" value="Haur_4077"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4077"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006232_0_0_0"/>
    <dbReference type="OMA" id="QDQRRFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4120-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="113"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="452"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1298" mass="145311" checksum="A7B37441BA3DA44F" modified="2008-01-15" version="1">MSQPNILTLECTAAAADSPDLAQWTLRLNQLTASGLLPALPTKEQRADFQWYFERYLDWPFLEFRERAMRVEAELATVGKALFAAIFESSANAAKIYAEWMQVDAGVPTLQILSLIPAVLSVPWELLHDDFGFLNQRRINPVAIYRTVSSVRSKIVAQQFAMPLRVLVVVARPDDQNFLDPRSSAQTIFGQLQQLENDQKLKPGMIELEFLRPPTYDQLARRLQDATKPVHILHFDGHGGFPKIQPTSTLYKSANVPQGVLSFEKADYQVDTVEARRFAELLNGAGVRLVLLDACQTSVMDTSASDDAEYQRQQALSSVATQLLTAGVPAVVAMSASVIVPTTALFFGELYGLIAEGQSVPVALERARQALQSQPVRLYLARNAEQEPDPISLADWWLPHFYQQAAINLTPTGKPARSKPTKLSGFIENPHQRPFVGRAKELLQLERALLKGKIALLHGFGGIGKTRLASEAAAWLTQTKLYQGALLLSFEHGGNQIALLSAIARHYELPETDSHDLQAALKRFKPHLHNKPLLIIADNLESILPNAGNVELNVLEAQERQALWDCVLGLRQAGAGIILTCRDYDLRDSRLQQGQYTSVIAMRGLDTPSAYSFATALLDDLAIDRRRAPKLQLSSLLARLDHHPLAMGLTLRALRDPALSIEQLLSDYSSALLQYTDETSPNQRHSSLEASLNYSLQRLSPEQREWLAKLAPFEGGASEDDLLVITEIPAEQWAQLRASLEHAALIVPVAIPGFEAPFLRFHPTLTPYLRQQHPASTELEQRFAVRYYGLSGYCYQQDRQNPQAVRALVRYELPNLQRAIQGLLRFKEIPAAVNMSDNLNKFYNNFGMQRERNLLNRQIAPYISSSEQLSEAEYLYESELGEVEYSQGHYELALKRFQQLLARIEQQLPDQLLNFQHCITLTHIGRCLQRMGQSTQSQRTYEQALAVIEQLLNHRLDDRDYLKQQALLITALADCHTDQGQFAQAKSSYEQALEIKKTIDDRRGQAVSLGQLGLLALRQRQYAEATQKYNAALAIYQQLNEPSIVASIYHQLGRVAEKQKNWTIAENYYRQSLTIKEGLHNNIGVAETCNQLALLAKSAGRSIEAEGWFKRALQNPDLPVLNRAKWLNNLADLLADQIQAGTWSQSRLAEAQNYAEQALNILKGVDPAQASLWLPLNILANLADPAGQAAEYCQQARIAYAAHAANRWHIDQQFGDLIAAIVTATQGNQEVRTAVEQTLPQLEANGWKISKAIQRIWAGERDWHGLCAELDNQDSLLILRVLEELEANSEGKSQKDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH1</accession>
    <name>A9AWH1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4098"/>
    <dbReference type="EnsemblBacteria" id="ABX06730">
        <property type="protein sequence ID" value="ABX06730"/>
        <property type="gene ID" value="Haur_4098"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4098"/>
    <dbReference type="eggNOG" id="ENOG5033ZD7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150257_0_0_0"/>
    <dbReference type="OMA" id="WIIEYID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4144-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025098">
        <property type="entry name" value="DUF4013"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13197">
        <property type="entry name" value="DUF4013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="28278" checksum="1A34B34E12CBD322" modified="2008-01-15" version="1">MAVERFQPLRALQTALRIVWSDRMWLPKVALGGLLGSSMFGVIWPQGLVIEHLDNSSRGYRLPLPAWRQFGDKAVMGLLATVMDFVYFIFPQLVAATFLFCAILPFIVGDNNSIATSITLIIFGTLFGVSFLGSFSPVSKLFFARDGAVEKALGRASFRRALGSNGRWVYFSARLVTLPVYLPAMGAAWWLWQLTHIPAVAVWWLLAALWLLMSCLFWAWLIVAQVYFEADQIVADREIEQRLADRKRAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWI8</accession>
    <name>A9AWI8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4115"/>
    <dbReference type="EnsemblBacteria" id="ABX06747">
        <property type="protein sequence ID" value="ABX06747"/>
        <property type="gene ID" value="Haur_4115"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4115"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_7_0"/>
    <dbReference type="OMA" id="GPFYDIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4161-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="34580" checksum="14F2D37A2C3D974E" modified="2008-01-15" version="1">MSKERILVVEDQADISGLLKIYFTSQGYEVMTAMRGQVALDLVKRTPPHLALLDVNLPDMTGYDIGKALRANARTKHIPIIFLTARGEKSDKGIGLGEVQANDYIVKPFDIEEVHMRVRNNLALAREKSRTHPVTGLPTAELINEELRRLLSAEVWTLATVHINGFDTFTQVYGSVVGEDVLKFGALLINEVVSELGGQEEFIGQLVTGPDFLITSMPERAKAIVDRIAERFDQEIGLHYSYPDRKRGYILAKNADGTERQEPLMTVSIGVLDSNDGPFYDIRELSETAESVRPLPNLQDGSVRSAVKFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWJ4</accession>
    <name>A9AWJ4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPDK_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4121"/>
    <dbReference type="EnsemblBacteria" id="ABX06753">
        <property type="protein sequence ID" value="ABX06753"/>
        <property type="gene ID" value="Haur_4121"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4121"/>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1832421_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4167-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPDK_N" evidence="1">
        <location>
            <begin position="43"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="14739" checksum="49121E920F8E6B9D" modified="2008-01-15" version="1">MNFLIALDQAATVEPALVGLVARDLAGTTPGFVLNTKVYHTAPHGEITPDVEAEIAQAYAQLAVEKVDLIASPAFAGTAPAEAATAFARFSAIQGIDKIVLAAERCWQSATSEAARKLYRDHAINPDDVQIAVVIIPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR3</accession>
    <name>A9AWR3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0666"/>
    <dbReference type="EnsemblBacteria" id="ABX03314">
        <property type="protein sequence ID" value="ABX03314"/>
        <property type="gene ID" value="Haur_0666"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0666"/>
    <dbReference type="HOGENOM" id="CLU_487262_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-677-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="588" mass="63330" checksum="64BDE0E7A223C576" modified="2008-01-15" version="1">MLDPQFQILIQDLTSSQMLDVSDRVTAATWRYTEQGCGDLSVTMPCTMPEAYWFKTLPFVYVKVFNRCSKRIWWGRAAGDDVTIIRTADGAVSIQILALGLVKALEDIPHTGWWSSTRYGDWQDVPSDLIPSRTPERFSFETERRLRIAPSGGNGFTTSSIGMLSIAQPAAASVQWQTIEASYTLKAPAGWRASLSRYDGTTFLSSLWTLDGVGIGATGITTQSGTLSFLSGVGCSRLGFNLFCTRAATNLHTAAITAGTRTVTPGTMAGIAVNAKLAIGGADPEEVVVTATTATTFTAVFRNAHLGSDLVEPLWDGNDGDIELVITNVRVKAVTTATVTLDQLAKYALSEVLAVNPWAVFNSDGKVQSPLVDIANLVAEDLPWATILSEQVQLGDTSNRPWVWGVDEDGVLFVRPRQSGRVWYVSTEQCSYTQGGNSDGRWTSGYGVYEDEQGQRQRTPIQTDAQALANSGLIRRTALMVDSGTLAVATQRTSVFLSDAAKGEAAASLTCAVLETVDGMVYPATEARPGDMLLFRDVLPTSSAVANRLNGFVLSEVQVDGFNLAAVHLVPEEPLPQLEMVTAKVGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ3</accession>
    <name>A9AWZ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate/guanylate cyclase with GAF sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2161"/>
    <dbReference type="EnsemblBacteria" id="ABX04801">
        <property type="protein sequence ID" value="ABX04801"/>
        <property type="gene ID" value="Haur_2161"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2161"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_305413_0_0_0"/>
    <dbReference type="OMA" id="RYFTAMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2189-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="838"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1020" mass="114170" checksum="FF30694DA261AD17" modified="2008-01-15" version="1">MPDASNGHVLIVEDDLSISRMFQLLLRDAGYRVSLANSSEEALQFVRVITPDIILLDISLPGMNGVDLTRHLRSNPAIPFIPIIQITALGDLRTKVAALDAGADDILVKPIELSELLARLRVMLRLQKNRRGLEESTRQMHILYAISQTLNSSLDINSILRDLVLQLANALGAVRTSIILVNDHNTPFYASSVKETLNTESIQRVIRDGVAGWVMRAMKPLIIADTTRDPRWISLDRRTETTRSILSVPLIHQGIVVGVVTAAHTRTNYFTQEHLELAQNIGNQSVTAFNHAQLFQTTVQQKSLLERRSQMLEELLNVGERLSLNLPLQDVLNELAQAIHRSLGFRQVIIHVFGIDDVEPAQGVAGVQREQIQQLWTNAQIQQSIVPLLRERFRISRSYFVPSGYKLDDEETNQLPFGAIGIRQADYLFVPLGSPQQLLGLMIVDLPNNLITPDLATIQALEVFANHGTTAVNNNRLFAREHTRANQLQLLVELGRNFAELMTPDQLLRLVASLVRHSFGFNSVAILLKHNNEFMLRAGTHNFAHHPYNQPLSIDARILQALEHYQSWLSSNSEQFCLNYEWGEPTIVAELIVPLHTHEGIQGLLVIGHSDASALDGLTQSILGAIAVQLTVGLDNAKLFLREQEYIQQLNRVNDIALQLTSTTTEPAFHEIMQQVAAMFQAPQSMLVLVDPEQRQINRSIAYPQSWLHELPALPELLASLDESRVQMLNHQHASALGQTLRQSEINTIVVAQLYSAERLHGLLLIKPADIHYVWRSNDRNLLQTLATLFAQALENQQLQAQRLERLRADLQRYMAPPLVEQLLSEGGFGEASERDIVVLFADLRGFTALSENLAPQVVVKQILNRFFDEMTAVLYRYDAIIDKFLGDGLMAVFGSVRPLPNDAERAMNAAIDMQQTFAKLQTEWQASFGYAIGLGIGMSCGRAVVGNIGSAQRMDYTVIGDVVNTASRLVGIAEAGQIIITQPLAQRLKRHKRQLEELEPVQLKGKRELQAIYAIRKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX77</accession>
    <name>A9AX77_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2245"/>
    <dbReference type="EnsemblBacteria" id="ABX04885">
        <property type="protein sequence ID" value="ABX04885"/>
        <property type="gene ID" value="Haur_2245"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2245"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099447_0_0_0"/>
    <dbReference type="OMA" id="VDRTTMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2273-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="46"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="24247" checksum="14E4C7ED26B93F8D" modified="2008-01-15" version="1">MKRFRGFRPSRLSLQPGRSLRWLAQLLLKIFGWQVEGTVPTEPKWIAIGAYHTSNWDFAVMLLATFSKQLRIYWIGKHSLFRFPFKTMMRWLGGIPIRRDKTYNAVQQVVDEIERHEKLVLVVAPEGTRKATDHWKTGFYYIALNAKIPIGMSYINYERKVLGFGPMLYPTGDIDADFAVLREFYERMSVGRFPEKQGTVQIKAPKAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXA6</accession>
    <name>RECA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recA</name>
        <name type="ordered locus">Haur_4194</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXA6"/>
    <dbReference type="SMR" id="A9AXA6"/>
    <dbReference type="STRING" id="316274.Haur_4194"/>
    <dbReference type="PRIDE" id="A9AXA6"/>
    <dbReference type="EnsemblBacteria" id="ABX06826">
        <property type="protein sequence ID" value="ABX06826"/>
        <property type="gene ID" value="Haur_4194"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4194"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040469_3_2_0"/>
    <dbReference type="OMA" id="DYGEQAL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_1000114341" description="Protein RecA">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <sequence length="358" mass="38036" checksum="F16863A932E78491" modified="2008-01-15" version="1">MAISPEKEKALAAALSQIDRQFGKGAIMRMSDQRLSIEAIPTGSIALDLALGVGGIPRGRVIEIYGPESSGKTTLTQHIVAETQKMGGVAAFIDAEHAFDPVYAANCGVNVEDLLVSQPDTGEQALEICETLVRSGAIDVIVVDSVAALVPRAEIEGDMGDSHVGLQARLMSQALRKLSGAVSKSRTALIFINQLRMKIGVMFGNPETTTGGNALKFYASVRLDIRKVESIKQGQDVTGARARVKVVKNKVAPPFRQAEFDIMYNEGISREGNIVDVGVTMEILRKSGAWFYLGDDRLGQGRENAKQFLKDNPALADEIEKMIRAASPGAPTAKVIVGAAAANGAAPADDGDGIFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXD2</accession>
    <name>A9AXD2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4220"/>
    <dbReference type="EnsemblBacteria" id="ABX06852">
        <property type="protein sequence ID" value="ABX06852"/>
        <property type="gene ID" value="Haur_4220"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4220"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099824_3_0_0"/>
    <dbReference type="OMA" id="WRIIGTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4267-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="70"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="20498" checksum="0221774B6912F5FE" modified="2008-01-15" version="1">MNSPVLVLNHNYEPLNICSARRALMLVLGGKAEVLEHNHAVLHTTNDTIACPSVIRLGHMIRRPLPNVKLSRREIFRRDHYTCQYCNRSSADLTLDHVLPRHRGGAHSWENLVSACRTCNHRKGGRTPEEARMRLIRPPFRPFASPYYLIERRMHGLGLEEWRKFLPASFQTVEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE9</accession>
    <name>A9AXE9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppc</name>
        <name evidence="13" type="ordered locus">Haur_4237</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4237"/>
    <dbReference type="EnsemblBacteria" id="ABX06869">
        <property type="protein sequence ID" value="ABX06869"/>
        <property type="gene ID" value="Haur_4237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4237"/>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006557_2_0_0"/>
    <dbReference type="OMA" id="PWVFGWT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX06869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="929" mass="104938" checksum="4A01B709F98C221F" modified="2008-01-15" version="1">MYTPETDRTPLSMLIHSLGNVLGDVIVAQDGVSAFELEEDVRQRTKQRRSDGTLQETQTLTELISQLPVAQLMGLIKAFTHYFGLVNLAESVERLRVLAERDRQNGDAPRSESVELALQELRDRGITAQQVQDLLDHAEIRPVFTAHPTEAKRRTTLKKHHRIAGAARQLTADTTFQRQRERLLESIREEVISLWQSDEVRIIKPTVIDEVKNNLYYFEESLFDMIPQLYRDTEASLRQIYPEHEWRVPAFLRFGSWVGGDRDGNPFVIPSVTVETLKLLMGRSLREHIHSVERLSHRLSQSSRQVPISEELAQSLIHDAPLFPELAQVLERRNPHEPYRQKCSYIHAKLHATLAYVERYEPDWARGGHRPAEGTWYANANQYLADLATMEYSLRTNGAASVADGFLRDIQCSAKVFGLHTATLDIRQHSSRHTNALSEIFEYAGICDDYASLSQAERTAVLERELANNRPLIPTHLYYSPETVEIIETFRTIRAVLSDLNAEAIETYIISMTEGPSDILAVLLLAREAGIYQPGEHSWLNIVPLFETGADLIAAPEIMHTLLSSEAYRQHLVLRNDVQEIMLGYSDSNKDGGFADAHWALYLAQVALAETCFRHRVAMRLFHGRGGAVGRGGGPANRAILGQPPGTVGGRIKITEQGEVISDRYAEPETAYRHQEQIINAVLRSSLGVSIAHISQEWHDAMSSLAKVSRKVYRGLVYDHPHFLEYFRNATPITEISRLNIGSRPASRKASDRIEDLRAIPWVFSWMQSRHTLPGWYGLGSALEHLIQADANGLTTLQGMYNDWPFFRTMLDNAQMILSKADMDIAAQYALLVPDQALANEIFGLIKAEYTRTVKWICEVAQINELLDTSPILQHSIKQRNPYVDPLSFVQIELLRRLRTDPDGLEHSDLEDAILLSINGIAAGLKNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL9</accession>
    <name>A9AXL9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0785"/>
    <dbReference type="EnsemblBacteria" id="ABX03433">
        <property type="protein sequence ID" value="ABX03433"/>
        <property type="gene ID" value="Haur_0785"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0785"/>
    <dbReference type="eggNOG" id="COG1287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033063_0_0_0"/>
    <dbReference type="OMA" id="WTAHEWL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-797-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="497" mass="55149" checksum="E84475B9F8F6C451" modified="2008-01-15" version="1">MAVGSLWLVAPEDFWWQLKIGDLIRTSGRIPTVGVFSATQANTAFFYQNWLSQFLFSWIYQLGGLVAILQIRSLLLIGSYALLLWHTWRRVKANGRAAMLGLLLSVLVSFNHWQVQPAMFVWPLFIASFVIVSEVAAERWTTKYLWLLPIIQLLWVNLHESFIFGPILVATAAVGAIIDRRRDHDEAPIYATARALQIATATTTIASFINPHGWNGWIAAWQQLTSIVPEALQTQSGSPLLNFATPMAQVSLAVGLIAAMMLSVVWQRMRSADLIITAIMAAFSLLSMRYQFWFGSVAGPIIAEAIVRRGRLRLIKRNPSAPIWIAGLTITIGLIGLLMQPIIRIWLPLPAALQGATGNLPQATLASAATPIQAVEFLQANPPSQAYFHDLGYGSYLIWQAGEQLPVFIDPRVSLYPTEHWQAYSCIMAGRDWERLLTQDSIDTILVDRGNGQQLISAVQANSAWREVYADQQSLIFKRDPQAAQPTGSATSCPATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXM8</accession>
    <name>A9AXM8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0794"/>
    <dbReference type="EnsemblBacteria" id="ABX03442">
        <property type="protein sequence ID" value="ABX03442"/>
        <property type="gene ID" value="Haur_0794"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0794"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-806-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="12914" checksum="FA6BD4E0B9C1A658" modified="2008-01-15" version="1">MVLVVDDSPFIRAFVAAALARIDVATCEAESVRAARAICHERALEAVVVDFELPDEPGVALCREMQRLSNVPVVLMSGHSEADVRAQFPLHQQPYFLAKPFTLNQIQGLIQQIIGVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXW6</accession>
    <name>A9AXW6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ordered locus">Haur_2292</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2292"/>
    <dbReference type="EnsemblBacteria" id="ABX04932">
        <property type="protein sequence ID" value="ABX04932"/>
        <property type="gene ID" value="Haur_2292"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2292"/>
    <dbReference type="eggNOG" id="COG0036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_2_1_0"/>
    <dbReference type="OMA" id="WLQVDGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2320-MON"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="183"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="205"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX04932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="24012" checksum="E5E5EF2CC76310C9" modified="2008-01-15" version="1">MPIGYHAGRAIELTPSILSANFANLGADVQAADEVGCSWIQVDVMDGHFVPNLTFGPPVIQAIRPFFKGTLDVHLMVSNPDALLEAYAKAGANHITVHQEASVHLHRTIQRIHELGCTAGVALNPATPVSSLDDIIEDLDLVLIMSVNPGFGGQSFIERSLAKIAAVRSLLDQRHHEAVIQVDGGVKPSNIASVVQAGATNLIAGSAFYSSTITPHQAWDAFVAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXX6</accession>
    <name>A9AXX6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2302"/>
    <dbReference type="EnsemblBacteria" id="ABX04942">
        <property type="protein sequence ID" value="ABX04942"/>
        <property type="gene ID" value="Haur_2302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2302"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1308718_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2330-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23187" checksum="2452CB8C71486A15" modified="2008-01-15" version="1">MLDLHPSFERATTDAVAHFTPLIEVIAAIAHGDATRRAEVEFLLPQIDNNGWQIQAAVEAIWAGERNFSQLSAGLDTNSAAIVQAILVAVSQTPDPEEARLSKLIGEWRPIILTVAAAHFGVQHAYTDLDGFLPQLEAQAQWQTLAQRLRLLVAGDTNRQRLLADLDTTDTVIMQAIFHALDDQATTLQLIREERDRAAAQEEAHEQQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXX8</accession>
    <name>A9AXX8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA dehydrogenase type 2 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2304"/>
    <dbReference type="EnsemblBacteria" id="ABX04944">
        <property type="protein sequence ID" value="ABX04944"/>
        <property type="gene ID" value="Haur_2304"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2304"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_2_0"/>
    <dbReference type="OMA" id="NPPMDDM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2332-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013107">
        <property type="entry name" value="Acyl-CoA_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08028">
        <property type="entry name" value="Acyl-CoA_dh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="3">
        <location>
            <begin position="27"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="2">
        <location>
            <begin position="129"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_2" evidence="4">
        <location>
            <begin position="252"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="42049" checksum="D6408EDAEB0AF076" modified="2008-01-15" version="1">MTIDLLHRGLTERQRGFVQLGQDLAALIKPSAGLHDQAASFPFEHLSAFFAARYQALSVPAEFGGHGASLFEAILAQEQLAYGDGSLALVMAMPIHVLGGIIEGGAWQPSQIERISRLVVDQSIVLNSAASEREMGSPARGGLFATVARQVEGGWLLHGRKIYTTGAPALTHALISATIADTSDTAIFLVDLKQVGITIEPTWNGTAMRAARNDDIVLDAVFVAEANLVQRRQPGLVDPSRNNAGAWFQLNMAAVYLGIAQAARDAARDYARERRPTALAGKAISELESIQRQLGKVEQLLLSARSLLYQTAQLWEQAPSERNNLRPLIATTKATAIEHAIAAVEQAMIVVGGASLSPDLALERYARDVRAGLFHPPTMDAALVGLGAWLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY0</accession>
    <name>A9AXY0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2306"/>
    <dbReference type="EnsemblBacteria" id="ABX04946">
        <property type="protein sequence ID" value="ABX04946"/>
        <property type="gene ID" value="Haur_2306"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2306"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="EFNILHF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2334-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="25404" checksum="CD43D873987AB875" modified="2008-01-15" version="1">MAATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLDGLAVFKTIRQTSNTPIIMVTARSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRSQPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALLATFMRHPNQILSREQLLEAVFAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ0</accession>
    <name>A9AYJ0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lant_dehydr_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0924"/>
    <dbReference type="EnsemblBacteria" id="ABX03572">
        <property type="protein sequence ID" value="ABX03572"/>
        <property type="gene ID" value="Haur_0924"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0924"/>
    <dbReference type="eggNOG" id="ENOG5033BPX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073591_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-938-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023809">
        <property type="entry name" value="Thiopep_bacteriocin_synth_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14028">
        <property type="entry name" value="Lant_dehydr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03891">
        <property type="entry name" value="thiopep_ocin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_C" evidence="1">
        <location>
            <begin position="49"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="39378" checksum="5B95578B123460F0" modified="2008-01-15" version="1">MPNPSQWHYRQVFLQPPNTPTPTKPDLRQVCDRMLLDWEKTFGEHGSLQPHIDRWFFIRYGEGGYHVRLRYQSPPEQRTTTIDPLLDAELLRFFQEHAATVGLAQTPQAIDELYAAGYLRDLTYEPEYAKYAGTLGMTLAEQHFAYSSAICLRVLQASAASGVARSFWVLELVHDLLEQFSPDPYVQALIVRSYLDYWIAQVVGDRAAFIQGLEQHYERQAPVIRQRLGSLRHNQQYPLFADWREHLRNHFADLQLAETKQQLQSSVTAHFQRYQAELPAILAEYPLTGLLFVPNYLHLVQNRLGLSVMQELQLLYMLYRVQIAELDVAPTSVPLILEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS6</accession>
    <name>A9AYS6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2414"/>
    <dbReference type="EnsemblBacteria" id="ABX05054">
        <property type="protein sequence ID" value="ABX05054"/>
        <property type="gene ID" value="Haur_2414"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2414"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000895_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2442-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1714"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1818" mass="199578" checksum="B344C9152D643B05" modified="2008-01-15" version="1">MEMDFQSIQRRFATAVEQRSSQAALRYHDQVVSYHELAEHAQRIASGLANQQVGVNTNVAIQLTNPIDVCSTILATLLLGARYALLSPNLAKLRLQQVLARQQFVLVGSAASNNLAANYIEFEQLANSELAEITPHSATAESLIGLSLASNPSGLIEAGQLSQTNLLSFIDFNLSKAKVSFQQSLWLGEEFNDFSAFASLATLASGGTLRFSTLETLDHDLDEQAQTLMLTLATLGQLFAQQSALPKVRHILSSGEGLLDGEALKQQLKQQQTAWHNYYGFPAFQLLTVVGANTQTQTASQIHSGKPVPHTQALILDQHKQLAPIGLTGELYVAGAGVFAGFEQAQLNAERFIASPFAADTQLYQTRYLARWQDDGRLSISGSLDSTIELAATPILLQEVERLLEQHPAIVECCIVRRITLSNTEQLTGFVVAKQRVEPSEILNYLEDQLDCQLANLGLIQVDQLPRTADGQLDRQQLAQTNLLDNRQIADLQAQLQQAANGAELAVVAQPILPVSSPLHIDDLVPMVETSNFGTSQRTISEQPVEMLSTQAKPALAVGPPLIKAEQAPLTLAEALVLAAKHYPEHGISYIEADGKALFQSYAALLADAEAVLAGLRAAGLKHGQHVVLQFAHNEPFVVAFWACMLGGFTAVPLALPNSSDPNNPAVSKLYNTWQTLEQPLIVSEQASFSLLQRIFNGLGVVKPAIQITEQLRQHQPDQQHQHLAPQDSALLLFTSGSTGLPKGVELSHHNIISRSKASAQHNRFDHNDVSLNWMPLDHVGGIVMFHVHDVCLGCRQIQAKTDYILEDPVRWLDLLEQYRATITWSPNFAYALINDQHERVNSRRRNLSSLRFILNGGEGINKQTALNFLGLLQAHGLPATAMHPAYGMSETSSGISSSDQLVLGATTGFHELDQASLTGVIQPASADSIGVAFVEVGAPLPGVSLRIVNTNNQLLSEDLIGRLQIQGPTITAGYYRNPELNREVFTDDGWFTTGDLAFLHQGRLTIAGREKDVIIINGINYHNHEIEALVETIEGVEVSYTAACSVPSKHTGGTESLVIFYVSKSAEFDQQLAQINQIREVVVQKIGINPSYVLPVAKSDIPKTAIGKIQRSQLSQRFINGEFSSITKPIDLALANQQTLPRWFFSKQWQPVSKRHNSALLKPSYAIFSDDTTLARELIDVLEQHHRDWVLISAGETFSQQGQHYTINLHDPEHYHQIAATLAATNIHDYVHLYSCDLPSEIEHVGDLAAAQYRGTYSLLFLTQALAKQKLSQASLTVVSQRSHAINQSDQVIYAAAPIHGLLKTMPLEIDWLSCQHVDLDAASATTNSQQIYYELAQPKPSAEVAYRAGQRLVPQLVEAEMAQSSPVESPLVKGGLYLVTGGLGGIGSQFARWLLQNYNARLLITGSTELPLGSDWAKHLGTDSSLSKRLRAYKDLIDISNDVHYQAVDITDSAQLARLINDAEQRWNQPLAGVFHFAGAGNLAYHWTVMDHHWITNESLATFEMMFAPKVYGTWALQRALSQRPELPIVAMSSINSFFGGATFSAYSAANSFLDSFMLHQRQTSHPKALCLNWTQWDNIGMSLNNPQQIRSLSAERGYNVIGLQQGLQSLLAGISQNQYPLLMIGLNADSPALRQHLAVSQPLQQRINLYTTHQHGPLSHDRYRQLANSYFGSATLEWYRVAELPRTSSGAIDLAALGQLDATNQQTALDQPTNIIEEQLVSIWQEILGKPKIGIHDNFFALGGHSLLATQLVSRLRDGFNLEVRLYQLFAAPTIAELANCIAELQLEQIDSAEMDALLAELEGLSEAELEAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ41</accession>
    <name>A9AZ41_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0939"/>
    <dbReference type="EnsemblBacteria" id="ABX03587">
        <property type="protein sequence ID" value="ABX03587"/>
        <property type="gene ID" value="Haur_0939"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0939"/>
    <dbReference type="HOGENOM" id="CLU_1000290_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-953-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="278" mass="30677" checksum="111C8362C8E415BA" modified="2008-01-15" version="1">MQGFNRLAMTIIALALAVLAITIALLPLQSFDLALRSLQYLRAQALIYSTTTRIVAGIGGLLLLGLALAQMFIRQSQYVPVRNTGSGYAQLDLQTIQRAVDQALGQALDVRSGKAQVQGYGEGVAIYTELELHPTAHLNDTLAYLHQSIREEVEERLGVAILTLKSKVKTQPYPNAPHSQPNEAGSAPELDPRQPAWDLRELRRRLERGILNQPNVVDLEVVLGYHPDGASVFVQLFLEKTAPVPSTIANVERLIHTIVADDFRLSVYELRVTSQIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZM2</accession>
    <name>A9AZM2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2528"/>
    <dbReference type="EnsemblBacteria" id="ABX05166">
        <property type="protein sequence ID" value="ABX05166"/>
        <property type="gene ID" value="Haur_2528"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2528"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070045_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2556-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="336" mass="37122" checksum="CD6FB1CCDCFCC856" modified="2008-01-15" version="1">MELIERYLAAVSNYLPAKQRSDILDELRSSIYDSLERNDQALDDEAAVVATLQALGEPAKVAAAYGNNQQYLISPALFPQFRSVVLLVFSIIIVSQLGLALLATIGNYHLNIVQVAWNAISNLPATFGLIVAIFWGVQKLEIEAETEPKKPFDPRKLPAITLANEKISRSSQLIGIAVQVILLGWLMQFQAEGGFRWVDGSGLFENPVISQYFALVVVASIFNVVVDLIVMWRGVWQTSTRIASLAASGFSLIVLFLLIRGHAAWLTNAGYPNSLRQLIRLGELIRENNPAIGMSSFYYGLSITAFFVIIDAGYTAYKLYQERSQAKYNNNIAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ9</accession>
    <name>A9AZQ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ABX07113">
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        <property type="gene ID" value="Haur_4481"/>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Larimer F."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
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                <person name="Richardson P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
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                <person name="Martin K."/>
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                <person name="Berry K.W."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Berry K.W."/>
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                <person name="Tice H."/>
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                <person name="Brettin T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1257"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1291"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1322"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1580"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1606"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1639"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1673"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1759"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1789"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1900"/>
            <end position="1918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1930"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1951"/>
            <end position="1967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1974"/>
            <end position="1998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2018"/>
            <end position="2038"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2059"/>
            <end position="2076"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2096"/>
            <end position="2120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2132"/>
            <end position="2154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2181"/>
            <end position="2202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2214"/>
            <end position="2232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2596" mass="286959" checksum="DCE347453AE34E15" modified="2008-01-15" version="1">MPRFAALRALGRRFPDLISLLCLLGILWMAWGVRSIHRADWDGYAPLIHPDEYYLKDAITPNLRVPDSFWSYLTTECEIVLNDQGVAQLKNARNPEEPDVSKQRPTATSGCNSLNPRTVDRGYVYGSLPVATVRYLTEKFYPEIEPDQLTSRTIAVVGRSVSSIADLISIVILFLLGRTLNSRRIGLLAGFCFAWSPALIQHAHFFVVDGQAAMYGLLTLYASTRLAQSRRWWSSLLNTIFAGAALALAVSCKITLAPLGGVIAIAAMVAYWHNPAYLRGDHSPAAIFQRLLWSGIYALPFAVLAFLVMWFTLRFSMPDAFNGFWFEERFVNAIANASATSSGEVDAPSSHQWAGRSNYTYELTNMIRWGMGVPLGVAAWLGWLAFGIALWRSESRQRLLGLLPIWLWTGIYFFWQGGLMIKPMRYLLPIYGPLILFAAWGLISLVDWARREGTPLLFRKVPLHGLAVGLTSMVAIVTLLWGWGFSRIYDRPHTRTQASAWAHANIPPGSTHTSDSWDIGIPGMENWIWTDIQLPIVNENDAGSIEQILQVANQANYLAFTSNRAYDSLDQLPMRFPATLNFFKGIFDGTLGYEKVADFTSYPSFLGIRIADDHATEDWSVYDHPRVTIWKRTERWNIDAARQQILADVNVDEIYKLRPKVATPMPTMLQQTVAEWREQLTSGSWAWVFEGVANSAPLIFWVLALELLGLAAFGLLWRLKLPLPDRGLGMARLVGLFALALIAWLPAAWHWWSFNRFWIAGVYLVLVALGSLSLLRSRHELRLWWQTRRAAILTSQAIYLAGFAILLTIRYLNPDLWHPGMGGEKPMNLAYLTATLKSVQFPPYDPWFAGGYMNYYYWGYVLMGTPMKLLAIRPEVGFNLALISLFAMTAQLSGSFGYNLLSTLGRAAKKIERRACFTAVGAAVALMLLGNLVQPVFYFNSARVLGNSELSWSNPEQSSQGIWLEGGSPVADAAAGFAKRLDGESFNLRPEWPYWNATRVIPPSTISEFPFFSFLYGDLHAHIIGLSLLVLLLLGLVGLYKAPTISGRALAGWSIALGILVGALKATNVWDYPLSLALSAVALLVVGWQQSRTVAWPKRWLWIVLPPIALFVAMTVVWSPFNRYLATGDYGKPQLLTNDQRMSIREFTVLYGLWFWILIPWMLLLARRIWGIRSTLIGVGSTLIWMAVISLLQDRVTLLDMSVEPSKIALLINNLFKQAIAQRAASIVILLPLTAWSIALLWSALAGRTRRREVVPLALTSAGILLLLLTETIVLPGAGRMNVVFKFGYEAWALLALAAASVVPLTLSAFRSVVRSALAAPLRISWATVTSLLVLGALVYPITATQAKVADRYVADAPRGLDGMAWMEGATWVENREIAIKDDAAAIRWMRANIEGTPTVLEASTSAYRWNSRIATWTGLPTLIGWDGHQNQQRAPAEAAGIIANRKNIIQQIYTAFDPNTAQNYLDRYGVSVIYLGGLERAVYGDLLPVFEQLKASGRWRVAYDSGTTQIYLRTDAKVPAPTALPPVELPGIPPDNPVAAISMAEKPLPQATVDNKVETPRVDGFADWAWINQNQAAAVLLWLLFFEVVGLLAFPIVAQALRSSLAAAWSASKIAGILLLGWLIWLPTSLGFWQWTRLSVIVGLAMLAALALAAWYFGAAQRIRQAWRQQRRAIIISEVLFISLFAVWTLVRAANPDLWHPYWGGEKPFEFGFLNAVLRSPNMPPLDPFYSQGTINYYYYGLYLMALPMKLFGLNSAIGFNLAVATVGALIGIGAWAVGLVVTRRLKVAAMALVAVALLGNLAGVLPIGTSTGIGGVVRAWQACELGGEGRETACAPLDGDSNLAAMISDAMANGTSENFTRRLAGGVPWFWGPSRVTVSDGLNTINEFPLWSVIFADLHPHLIALPITLLVVALAWEVSRRRRLRRQLPAFGLAALAVGSLAAANAWDVPTYGLVLIVGLMARGWQAPQRRWWATLGYSLLGVATVALGLLLYAPFLGSYKAPVGGVWPIRVGTALVPWLAIYGLFLLMITTWLLLPLKRAEPTPFWDWVKATRGRWLIGYGLAAAAVIVYFLTRSDAAKSAITEPSVLPDLATIYKPIFSAGIPVRLLIGLLLAGLIRRFINRVASPSARWAIVLGLVGGLVALGIELIFIRDHLAPGSWDGGPGDSERMNTVFKFGYQVWVLWALSAALLLPHIASALRNSRVAKYSWQTAVSVGVVLALFFPIFGTLSRVGMRFDKPLQGLTLDGLAYMQTAEYSVNNGVVNLADDLTAIRWITENITGTEILLQSEQEFYRAFGVRITANTGLPTVISALHAGEQRPGPLVDQRIRDVMEMYSSLDVLRTQWLLNKYGVDYVYVGQIERLRDPMGVDKFVTMAGVQQVYQNNSVTIYKTTPQLRELAMQWRDGVVPAPVVPNTPVDQAGNQVEAAVALYESDPNNAGYAFEAGKQLWQAGQADRAAAILGRAADVHPNDIGLHHLLGDVLLSLKRYDQVVLAYEQAYNAGPTPQNQTKLGQGYFAWAELDRTKLDAAAAQFSAAIIADSQFADPHYHLAEVYRLQGNNAEARREYETYLSIAPPEGLWVGSAQERLKNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E6</accession>
    <name>A9B0E6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05255">
        <property type="protein sequence ID" value="ABX05255"/>
        <property type="gene ID" value="Haur_2617"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2617"/>
    <dbReference type="HOGENOM" id="CLU_1693094_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2645-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17046" checksum="13DE1F9CE41FF2D4" modified="2008-01-15" version="1">MLLLVACGRISLQPVNPTAGPVEYALQQGGNIFGPNAVVQTAKNCWESQESKPIVMQIEAGSVDFDFAQTRFYIEGPLGDAKQRYYWEPIDPPARLAANGAVFQQVWTAPITQEGDYTLYVEASWYQQPTGFGFGVGYITDASTLTTIRCADLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J2</accession>
    <name>A9B0J2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4579"/>
    <dbReference type="EnsemblBacteria" id="ABX07210">
        <property type="protein sequence ID" value="ABX07210"/>
        <property type="gene ID" value="Haur_4579"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4579"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="TQRFSYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4634-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="33317" checksum="071606BBA4DCAB93" modified="2008-01-15" version="1">MTTVVQTTNLTKTYGKNRGIDSLNLHVQQGEVFGYLGPNGAGKTTTIRTILDFIRPTSGTAQIFGLDSQRDSVVIHQKISYLPGELVMYEKMTGMEMLHYFGQLRGNVSQQEIKQLAERLELDLKRPIRTLSKGNKQKVGLVQAFMGKPELLILDEPTSGLDPLVQQTFYQLVLEAKATGRTVFLSSHVMSEVDHICDRVGIIRAGKLLAIDTVKALKERARRTIDLYFTQPVELSAFAHIPNIDGLQVLGNHVHCAVTGSIDQLIKTAAQFELHDVVSQATDLEDIFLAYYKGEMSDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K8</accession>
    <name>A9B0K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX07226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4595"/>
    <dbReference type="EnsemblBacteria" id="ABX07226">
        <property type="protein sequence ID" value="ABX07226"/>
        <property type="gene ID" value="Haur_4595"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG4987">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="VSHNATF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4650-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02868">
        <property type="entry name" value="CydC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
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        <location>
            <begin position="16"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
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            <end position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="365"/>
            <end position="372"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="547" mass="59644" checksum="0763C8F9CD4C7149" modified="2008-01-15" version="1">MKRLLQLFYAERWQVLLVIGLGFATVGSSVGLIATSAYLIAKAALMPSIAELQVAVLGVRFFGIARGVLRYAERYLSHRLTFQILAQLRSWLYAALEPLAPARLLHYSRGDLLTRTISHIDSLQHLYVRAIAPPWVALLVALATSLLIGSFVWQLGLVLLLCHLLIGVVVPALSLRQSRQPGAKVNQQKQALNQAVVEAVTGSADIMAANAELLVQQQLTQLSQQLATSQRRLTNARITSTSLLNALVMLSTLLMVGLGSWFVEQGQLNPLYLAVIGLSTLASFEALGNLIQAAHIWQSSQQAAKAMFELVDARPAVSDPAEPSKLSTSSQIRFEHVDFGYVENQLVLRDLSFELAPGEIVALQAPSGAGKTTVAQLLLRFWDVQAGAIYLGDCDIRQLRLADLHQQIGYVSQHTELFNGSLRDNLRLANPAASEDDLVQALEVAQLSNLLAKLPAGLETWIGEQGAKLSGGERQRLALARVLLKPAPILILDEPTAQLDYANEAAWLAALKPLLADKTVLLISHRRAVQALADRSIYLEVSDTRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N6</accession>
    <name>A9B0N6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="6 7">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4623"/>
    <dbReference type="EnsemblBacteria" id="ABX07254">
        <property type="protein sequence ID" value="ABX07254"/>
        <property type="gene ID" value="Haur_4623"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4623"/>
    <dbReference type="eggNOG" id="COG2259">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_3_2_0"/>
    <dbReference type="OMA" id="TCYDRRD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4680-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="14926" checksum="EAD4FA9A9CEBA32D" modified="2008-01-15" version="1">MKSAQLSAIGWTLLRVVVGMVFVIHGWSKVTMIGGVAATFGNEYQLPIPAVLAWLVATIEFLGGLALTVGVYSRWAALLLSCVMLGAIKVHWGSFFYYANGMEYDLVLLTVCTVICLNGGGPYSVDTMIINKPPAKKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B133</accession>
    <name>A9B133_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ABC-2 type transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2673"/>
    <dbReference type="EnsemblBacteria" id="ABX05311">
        <property type="protein sequence ID" value="ABX05311"/>
        <property type="gene ID" value="Haur_2673"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2673"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046841_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2703-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="44646" checksum="24FF464600679F37" modified="2008-01-15" version="1">MSKAKWWTIAAHEYSVHAKRKGFLLATFGTPLLLGAIFGAVIAFVAFGNQSNNLGVVDQAGITTQLPATVTITDTLRKDVDVIRFSDENLAKNALSNQEIDGYLVIPNDYLQTGALRGVAAEGNLNSDAQGRFKNYMQKALISHQAPLDSVRALEPISEVYNRKPNSNAEISEAQGVLLFFTPYIFGIFLFITVFSSSAYLMTALVEEKESRVMEILATSMRPFELMLGKIVGLGLVGLTQISIWVGTALLGFMIARANIDDLANLTLPTNVLLIGAIMFVPAYLMVAGALGAIGAGVSAVQEGQQFSGVVSLLMISPVWFMTLIIENPNGFLAVFLSIFPFTAPIVMMQRVALVSVPAWQLGLSVVVLVGMAIAMIWLSARIVRIGMLRYGKRLSWVDIRRALSLGGQHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A2</accession>
    <name>A9B1A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mucin 2, oligomeric mucus/gel-forming</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_4658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4658"/>
    <dbReference type="EnsemblBacteria" id="ABX07289">
        <property type="protein sequence ID" value="ABX07289"/>
        <property type="gene ID" value="Haur_4658"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4658"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_353659_0_0_0"/>
    <dbReference type="OMA" id="FTWTCTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4715-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="794" mass="80386" checksum="3D8BBCD25087216B" modified="2008-01-15" version="1">MGCSSLMVVRWTTPVNASGPEVLLPPFANYEAWNGTAPFPIGQEAIRSKISDQPANPNLVAAETPIPIGIVDLLPTATPTGRPTPANEAIVTSTTTTTPTPTKDEGIPIGSATAATTEPTIELTAEPSSTPRVNPSSTAGTRTPTLNPTINPTRPTFEPTFTSTPTRTSVVVATTVVPASATSTNTAIPTSAPTATNTRVPTITPVPATLTNTPTDVATITPVPATPSNTPTDVPTNTPVIVTATNTPIPIFTTPSNTPTNTATNTPSNTPTNTATPTNTPSNTPTDTVTPSNTATPSNTPTPTDTATPTATPAPELYIAWRVDAIVNPVNPSMENNDTKQVFVVFGNAGDAPASGAQVNISVTGTCISSSISSSGVPITLGAHQGFTLSPTISANNVGNCSITAVLTAIGQTPVQATLNWTIVCDGCATVTPQPTNTPTRTPTNTPTRTPTPTNTATPSNTPTPSNTPTATNTHTPTTIPTLTYTPTPSNTPTVTNTPTPSNTPTNTPTPSNTPTVTNTRTPTNTPTITNTPTPSNTPTVTNTPTPTSTPTPTSTPTVTNTPVDTPTPSETPTPSETPTPTSTPTPTPDLFVFHIVNGVVNPAGSMTLAAGAQENVTVVFGNNASGSRATGLNFSFSGGACISAQPGSSDSSDLNGGVNRSLSVIVTGNAVGSCSFRTQFSASNANTVSVDSSFTVVNTALNQPAIAATATATSTATATATAEPTATLAPTAMPTDQPTAEPKATLEPTLPVIGQSSGFPPMSGGQMLWLLAGGLAILLSGLRGRRILPLNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1C7</accession>
    <name>A9B1C7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4683"/>
    <dbReference type="EnsemblBacteria" id="ABX07314">
        <property type="protein sequence ID" value="ABX07314"/>
        <property type="gene ID" value="Haur_4683"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4683"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_8_6_0"/>
    <dbReference type="OMA" id="CHATDPN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4740-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="85"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="564" mass="63001" checksum="F9E96BE9C41EADC3" modified="2008-01-15" version="1">MVRRIRWQIGATLVCASLVLLLLAHLALATTAGGEAGVGGVYREALVGEVNDLNPLRGSAQTRAEADLSALLFEGLTRVEATGVVVPDLAENWQVSSNNLVYTMTLRTDVRWHDATPFSANDVIWTIDWIKSPQFNGDPSLKLAWQNIAVTALNPQTVRFNLPVAFAPFLNQLTVPILPAHLLRNATPDQWQAWNQQPVGTGSFRFGKRDGNLIELLANTDYRPNIPNSRPNLERLEFRLYATMEAAHEALRRDLVDAFAYDVTEQGELPLPIGYRQVRAPLADYVVLTINLRRPPLDDLRVRQAIDYAVDPTTLITEVLQNRALPLNSPILPSSWAVAEGLTGYIDDAEQSRANGLLDQAGWQRDAEGWRRKAGQLLRFDLVSANSPERSAIAERIQAQLATVGISSSLQLVPSSNLQDTLSQHTFDLAIHGWSNLGSDPDVYELWHSSQVNAANFAGLEDPAIDDLLVRARQTTSQETRRELYAEFQAKWLALAPSVMLYQPLLEQQVGPSIEVLGLAPINQQAEVLYRHSDRFRRIANWYLVSTRQVLPNFRNEPQNERPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D9</accession>
    <name>A9B1D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4695"/>
    <dbReference type="EnsemblBacteria" id="ABX07326">
        <property type="protein sequence ID" value="ABX07326"/>
        <property type="gene ID" value="Haur_4695"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4695"/>
    <dbReference type="eggNOG" id="COG4312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066898_1_1_0"/>
    <dbReference type="OMA" id="LIVYNHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4752-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010296">
        <property type="entry name" value="DUF899_thioredox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05988">
        <property type="entry name" value="DUF899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29851" checksum="43855C032F92C8D3" modified="2008-01-15" version="1">MSNRTNDLIPLSDMHGPSLPAAVDRATFQAELNSLRVREKAHTREGDAIAAARRRLPMVEVAATTLVVGPNGLVPLIEVFEGRKQLFAAYMMWHHGANAAQQCEGCTMNVGHVLELGYLHSRDVTFAVLSQGPFAESNRYREFMGWELPWYSVPESSLDALIADRHFGIWVCYVQDNGRVFETYWTTGRGCEQMGSSYAMLDMTIYGRQEAWEDSPAGWPQRFFNTRSAQMRTDEHDQAVNRPAGRPISHWSRLAAGRSDDIIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E4</accession>
    <name>A9B1E4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4700"/>
    <dbReference type="EnsemblBacteria" id="ABX07331">
        <property type="protein sequence ID" value="ABX07331"/>
        <property type="gene ID" value="Haur_4700"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4700"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_0"/>
    <dbReference type="OMA" id="NCVAPMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4757-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="36958" checksum="75482D481CA01391" modified="2008-01-15" version="1">MARVAINGFGRIGRQSFKTILDHYRDELEIVAINDLTDNQTLAHLLKYDSTYGSFDGDVTATEDTISVTFADEEEPMVIKALAERDPSKLPWGELNVDIVIESTGIFTDATKAKMHLDAGAKKVIISAPAKNEDITVCMGVNEENYDAEKHTIVSNASCTTNCLAPVAKVLNDKFGIVRGLMTTIHSYTMDQNLQDGPHKDLRRARAAALNMVPTTTGAAKAVALVIPELKGKFDGFAVRVPTPTVSMVDFVVELAEGATVESINNAFIEASEGAMEGVLGVTNEELVSSDFIGTSYSSVVDLSLTMAMGDKMVKVVAWYDNEWGYATRIADLTAYIAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G9</accession>
    <name>A9B1G9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4725"/>
    <dbReference type="EnsemblBacteria" id="ABX07356">
        <property type="protein sequence ID" value="ABX07356"/>
        <property type="gene ID" value="Haur_4725"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4725"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_0_0"/>
    <dbReference type="OMA" id="IHEWPYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4783-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="139"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="38758" checksum="A31E02CDC9829051" modified="2008-01-15" version="1">MSQERLAALRMLFEAAQIDGLLVANSQNRRYLSGFTGSAGLLIIDAQRALLISDGRYTVQAAQEASQFETITRTLDESLYSCVGRHIAPIKRLGFEPATLSVADYNALRQALPADVTLVAIGALTEQLRAIKSDEEVAALRQAINITDQALAAVKPMLRPSMLEREVAWELHKAIVEHGGDGLAFEIIVGAGLNSALPHYHAGNAPLGQGQPIVVDFGALYAGYHGDMTRTLVLGQPDAKFDEIYGIVRHALADATNGITANTTGKEADALARDVIEASGYGEYFSHGTGHGVGLQIHEEPRLSRVHNDLLPVGSIFSIEPGIYLPDWGGVRLENLVLLNANGVETLTQSPLDPIIVIEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1H4</accession>
    <name>A9B1H4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="4">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="4">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="4">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mobA</name>
        <name evidence="6" type="ordered locus">Haur_1211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MobA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1211"/>
    <dbReference type="EnsemblBacteria" id="ABX03859">
        <property type="protein sequence ID" value="ABX03859"/>
        <property type="gene ID" value="Haur_1211"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1211"/>
    <dbReference type="eggNOG" id="COG0746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055597_2_2_0"/>
    <dbReference type="OMA" id="HENGYIE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="5">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="22117" checksum="FD45617CC59717F5" modified="2008-01-15" version="1">MMAELGCVIIAGGKARRFGSDKRRLRLWGEHGPTLLEHTLAVAQTVCDQVVISLNDPLEWPELSVPLLQDAVPDVGPLAGIVAGMGLLATEWTLVLAADLPLLSSELLHKLIALPRHGLAVVPQRQADSQRHGGWEPLCALYKRACLPHFEQALAAGRYRLTQLIEQFQPQVWPIASTSPWYQNLHNLNRLDDLHQLATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q9</accession>
    <name>A9B1Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1296"/>
    <dbReference type="EnsemblBacteria" id="ABX03944">
        <property type="protein sequence ID" value="ABX03944"/>
        <property type="gene ID" value="Haur_1296"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1296"/>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_5_5_0"/>
    <dbReference type="OMA" id="IECRAVI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1318-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9026" checksum="CA42F638210B98DD" modified="2008-01-15" version="1">MVLPVINLQRCIACGACEHVCPTAAVAIEQQHAVLVKPEACTFCDRCEIACPTEAISRSFAIRFAPSSQPLTKAQLGQLNLGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S3</accession>
    <name>A9B1S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2727"/>
    <dbReference type="EnsemblBacteria" id="ABX05365">
        <property type="protein sequence ID" value="ABX05365"/>
        <property type="gene ID" value="Haur_2727"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2727"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_0"/>
    <dbReference type="OMA" id="DKMFLDN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2758-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="329"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="372"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="649" mass="72906" checksum="861B839F65F7E2C5" modified="2008-01-15" version="1">MSVLIANNLGKWFGAEQIFEAVSFQVARGDKIALVGVNGAGKSTLMKIIAGIDSSSEGSLHRSRGLRVTYQAQEATFAADSTLEREAHAAFAALSNIEDEMRQLEVTIANPDDPQWEQAMERYGELQHRYEHAGGYEKEHRITRTFQGLGFTDAQWTQPIAQFSGGQRTRAALAVALLGDPDILLLDEPTNHLDMAALEWLEDFLRDWEGTLIVISHDRYFLDRVSNRTWEMEWGRLQDYAAPYSKYQTIKAERMERLAKEFEAQQQMIAKTEEFIRRFKAGVRAREAKGRERRLNRFKEGWNSIHGHVKAIEGPQRRKELKFALQTNLRSGDVVLALDQLGVGYTNNGQTTTLLQFDELYVMRGERVALLGPNGSGKSTLLKTVVDQLKPLAGSFEVGANVQLGYYAQGHEGLDFNNTILDEVLRHNPQMGETRARTMLGNFLFTSDDVFKQIRDLSGGERSRVALSQLMLNGGNFLMLDEPTNHLDIQAREALEGVLNDFNGTLLFVSHDRYFIDAVADTLWLVNDDGSITRFPGNYSALAAQRENERRAAEAAAIEAKRAAERQTKANKANPTPVPASAKRQLQNLEREIASLEQRKAALDAEIMQASIKQDSRKIGELGTQYAALENQLSDYYTRWEQLAEEVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S7</accession>
    <name>A9B1S7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2731</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2731"/>
    <dbReference type="EnsemblBacteria" id="ABX05369">
        <property type="protein sequence ID" value="ABX05369"/>
        <property type="gene ID" value="Haur_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2731"/>
    <dbReference type="eggNOG" id="COG2076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133067_1_2_0"/>
    <dbReference type="OMA" id="FEIAWAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2762-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="108" mass="11088" checksum="601E8D11C0CFC3A6" modified="2008-01-15" version="1">MAWFYLIVAGVLEVGWAVGLKYSEGLTKLGPSLATGVMLAASMALLGMALRDLPLGTAYAIWTGIGTAGTAILGIWLFGESAQPLRLACLVMIVAGIIGLKLLAGKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T4</accession>
    <name>A9B1T4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2738"/>
    <dbReference type="EnsemblBacteria" id="ABX05376">
        <property type="protein sequence ID" value="ABX05376"/>
        <property type="gene ID" value="Haur_2738"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2738"/>
    <dbReference type="HOGENOM" id="CLU_1233655_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2769-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="22840" checksum="6D8BADA112C828C8" modified="2008-01-15" version="1">MPDSPDPLINQPATSNSAQGYRIQATIMANHNQPSRWVDWVIMNGVAFVISCIVFPILLVGCLLIFAGFTESASATQAQISDGFGLLFVVGIPAFVTMYLASFLQWTTVSEGINRSTWVTNSATVGAITLTVWIYHLSPITAQSIKNYNQVIILTFGITSSSISWAQWLELRKTIDQAWQWALISIITWTGLGTLIFGFGLSYLVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z3</accession>
    <name>A9B1Z3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2797"/>
    <dbReference type="EnsemblBacteria" id="ABX05435">
        <property type="protein sequence ID" value="ABX05435"/>
        <property type="gene ID" value="Haur_2797"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2797"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_7_0_0"/>
    <dbReference type="OMA" id="NHFTIHA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2828-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01320">
        <property type="entry name" value="ADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38333" checksum="7204F02519C1BF81" modified="2008-01-15" version="1">MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLGFLDVYRTCARCLIHGEDFERVAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGVAAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAGMQYGVVAFSIGGDEANYPPEPFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARRGDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAERYDFTIDDICKVARQSAKAAFLPAEQRQQLLLEFDQQQAQLRRELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B216</accession>
    <name>A9B216_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4735"/>
    <dbReference type="EnsemblBacteria" id="ABX07366">
        <property type="protein sequence ID" value="ABX07366"/>
        <property type="gene ID" value="Haur_4735"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4735"/>
    <dbReference type="HOGENOM" id="CLU_1292919_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4793-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="23126" checksum="CDAE96BD0334F646" modified="2008-01-15" version="1">MNMHTKAIRCDRLTKDFALYLNGELIGYSSSYSEGESRLNELVYDLLRRASHADISDLTPEDAEVALEVVTALATEETVTEVVPTDATTQVEVKSMADDESGKETHGVPVFSSTIGGIECTLGTDGALTVSAARRDEPAYGRSPDDTDALYLFLTKLPQVGPLLEGTHMERQHFLYGDMEIKTNDEGFDAAPSIVAHLAKARREKETVAANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B258</accession>
    <name>A9B258_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ordered locus">Haur_4777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4777"/>
    <dbReference type="EnsemblBacteria" id="ABX07408">
        <property type="protein sequence ID" value="ABX07408"/>
        <property type="gene ID" value="Haur_4777"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4777"/>
    <dbReference type="eggNOG" id="COG1077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052037_0_0_0"/>
    <dbReference type="OMA" id="MVICIPS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4835-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="353" mass="37764" checksum="C6BBDF06017B7C56" modified="2008-01-15" version="1">MFRSFFRSFSRDIGMDLGTANTLVYLRGKGIVISEPSVVAIDKRTGIPQAFGAAAKAMVGKTPANIVAVRPLRDGVIADFDVVEKMMKYFFDQAHKHVGASIAGRPRVIVGVPSGVTDVEKRAARDAAMNAGAREAYVIEEPMAAAVGAGLPVTEPTGSMVVDIGGGTTEVAVISLGGIVINHSLRTAGDEIDEAVIAFARREYNLLIGERMAEKAKIAAGSAYPLEEEIKVTLRGRDLLTGLPKAIEISSIELREGIAGPVANIVSEVRTALEETPPELVADIMEHGITLAGGGSMLRGLDRRIAAETKMPVHIAEDPLSCVARGTGKMIEEFDKYRDTIRRSQESRRIKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A7</accession>
    <name>A9B2A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1304"/>
    <dbReference type="EnsemblBacteria" id="ABX03952">
        <property type="protein sequence ID" value="ABX03952"/>
        <property type="gene ID" value="Haur_1304"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1304"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_2_0_0"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1326-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="14"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="14"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="111"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="111"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="216" mass="23141" checksum="1E9899603624CFD1" modified="2008-01-15" version="1">MNLTPSPSLRKIAMFTGIVEEIGTILVANTGLERDNTLRIGCTLATSDAQLGDSIAVNGVCLTVTAFAADWFEVGLAPETLRRTNLGQLKVGSSVNLERALAAGRRMGGHYVQGHVDGTGEIIAIEPDGESKAITIRVAPALMRYIVEKGFIAVDGTSLTITRTTDDSFGLAIIAHTQAWAIIGQQQVGDTVNIEVDILAKYVENIVRFDRKMLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C2</accession>
    <name>A9B2C2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1319"/>
    <dbReference type="EnsemblBacteria" id="ABX03967">
        <property type="protein sequence ID" value="ABX03967"/>
        <property type="gene ID" value="Haur_1319"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1319"/>
    <dbReference type="eggNOG" id="COG1231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004498_10_3_0"/>
    <dbReference type="OMA" id="IPKPHKV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1342-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735200" evidence="2">
        <location>
            <begin position="26"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="59"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="470" mass="51570" checksum="49AB4A7258D73F3D" modified="2008-01-15" version="1">MSYTRRDILKLAALVSLSPWLPACAPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIAGLAAAAKLQANGYRVQIIEGRDRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADTARIERTPTDYENSLVYTMDGEELDDAAVEQLEEQLVTLLDAVAELVEDTDDMSLAAAMQQVLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILDQLTADLTIHTGQPVNAINYTAESITITTNTTTFEAEHVIITVPLGVLKQGRIQFTPPLDATKTDAITLLGSGLLNKTWLRFPTAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDSPILLGFNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAWQITRWGADPYAFGSYSFLGVGATDALRDDLAQPIAGRLFFAGEATERTYPSTVHGAYLSGLRAADEVMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C3</accession>
    <name>A9B2C3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03968">
        <property type="protein sequence ID" value="ABX03968"/>
        <property type="gene ID" value="Haur_1323"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1323"/>
    <dbReference type="HOGENOM" id="CLU_1774876_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1344-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732369" evidence="1">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="15663" checksum="880D0E81938DE4F4" modified="2008-01-15" version="1">MRAWICLAVMIVLTGCGGAATPTVFPTNTPMAMDEPPLFTPPSAKPYAGGDEQIDVFLAALKNVDTVGTVTDQAFYRVTESTVEVFQFYRDSYASDTIEGGPPQPSATTLIIFIKPRSVDYQIMVTYVRLGAIGHPGGLLGVTVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K6</accession>
    <name>A9B2K6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase containing von Willebrand factor type A (VWA) protein-like omain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2819"/>
    <dbReference type="EnsemblBacteria" id="ABX05457">
        <property type="protein sequence ID" value="ABX05457"/>
        <property type="gene ID" value="Haur_2819"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2819"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_254726_0_0_0"/>
    <dbReference type="OMA" id="YYDRDVW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2850-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732375" evidence="2">
        <location>
            <begin position="32"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="802"/>
        </location>
    </feature>
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        <location>
            <begin position="833"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="929"/>
        </location>
    </feature>
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        <location>
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            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1394" mass="139882" checksum="5F2647436742A927" modified="2008-01-15" version="1">MNFDRSRRNYGRLLLALIVVLHLGMVRSAAAAGETPYANAVDSSTSGLIVNAANSVGAPNGTVATVIGLLGQNLTLDMGANEEGTGDLVVHYGGIGVQLAANVQFLNASRQVIASSSLDIVGLSLGTIYTTTVDYPQSPTPYRYVRFVSLLTAYQIDAVEATTFRPDSDNDGVNDVDEITNGTNPLDPDSDDDGLTDGEEITNGTNPNDSDSDNDGLPDGWEVDNGLNPNNGTGATGATGDPDNDGSSNLDEYQNGTDPNDPDSDDDGLNDGAEDSAGTNPLDNDSDNDGLPDGWEVNHGLNPLDATGNNGAAGDPDNDGSNNAAEFAAGTHPNDADSDNDGLNDGAEAALGTNPNNADSDGDGLPDGWEVSNSLNPLNATGNQGATGDPDNDGSTNLQEYQNSTNPHDADSDNDGLNDGQEAAAGTDPNDSDSDNDGLPDGWEVANSLDPLSSVGDDGAAGDPDNDGSNNAAEFASNTDPNDADSDNDGLNDGQETAAGTDPNDSDTDNDGLPDGWEVANGLDPLSSVGDDGAAGDPDGDGSNNAAEFAAGTNPNDADSDNDGLNDGPEAAAGTDPNDADSDNDGLPDGWEVANSLDPLSSVGDDGAAGDPDNDGSNNAAEFASNTDPNDADSDNDGLNDGQEAAAGTDPNDSDTDNDGLPDAWEVANSLDPLSSVGDDGATGDPDNDGSNNAAEFANSTNPNDTDSDNDGLNDGQEAAAGTNPNDSDTDNDGLPDGWEVSNGLDPLNPNDAAGDPDNDGLDNSAEFANNTNPQDSDSDNDGLNDGAEISAGTNPNDSDSDNDGLPDGWEVVNSLDPLSSVGDDGAAGDPDNDGSTNLQEYQNGTDPNDADSDNDGLTDGQEAGLGTNPNNADTDGDGLPDGWEISNNLNPTSTTEGNGANGDPDNDGSTNLQEYQNGTNPQDADSDNDGLNDGQEAAAGTNPNDSDSDNDGLPDGWEVANSLDPLSSVGNNGAAGDPDSDGSTNATEFANNTDPQDADSDNDGLNDGQEAAAGTDPNDSDSDNDGLPDGWEVVNSLDPLSSVGDDGAAGDPDNDGLSNAGEFANNTNPNDSDSDNDSLPDGWEVNYGLDPLSSVGDDGASGNPDGDSYDNATEFANGTSPIVFDAPAATNTPEPTLTNTPEPTATNTPEPTATDVPTATATDVPTATATDVPTATATDVPTATATNTPEPTMTNTPEPTATDVPTATATDVPTATATNTPEPTMTNTPEPTATDVPTATATDVPTATATDVPTATATDVPTATATDVPTATATDVPTATATDVPTPTATNTPEPTATNVPTATATNVPTATATNVPTATATAIATATATAIATVTNTPIPTVTATAIATATATATATATATLTPTLTPTATATSTVQPTQNKIFLPMAMKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X4</accession>
    <name>A9B2X4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3401"/>
    <dbReference type="EnsemblBacteria" id="ABX06037">
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        <property type="gene ID" value="Haur_3401"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3401"/>
    <dbReference type="eggNOG" id="ENOG502ZW25">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098984_0_0_0"/>
    <dbReference type="OMA" id="HVCPRQN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3438-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="InterPro" id="IPR021441">
        <property type="entry name" value="DUF3090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11290">
        <property type="entry name" value="DUF3090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03847">
        <property type="entry name" value="TIGR03847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="22372" checksum="83A7BAA5BB062A4E" modified="2008-01-15" version="1">MSDFVYDLRRVSHITAAAVGQPGQRTFYLQAQKGSDLVSLITEKELVRALCLRIDDILEELDKRGVARPDASEEPTPAELLLRPPLNPFFRIAQMSLAYDPTSDLLVIEVEEFQLADDEDDEEIDPILQQNAEAEEGKNDPRRVRISATRAQMQALSRNAMDIITTGGRPICPQCLQPMEDEGHLCVKKNGHGNKKASEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y8</accession>
    <name>A9B2Y8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3415</name>
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    <organism evidence="1 2">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3415"/>
    <dbReference type="EnsemblBacteria" id="ABX06051">
        <property type="protein sequence ID" value="ABX06051"/>
        <property type="gene ID" value="Haur_3415"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3415"/>
    <dbReference type="eggNOG" id="COG2308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017048_2_0_0"/>
    <dbReference type="OMA" id="VLTPGMY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3452-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025841">
        <property type="entry name" value="CP_ATPgrasp_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016450">
        <property type="entry name" value="UCP005522"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14403">
        <property type="entry name" value="CP_ATPgrasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005522">
        <property type="entry name" value="UCP005522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="480" mass="54058" checksum="A7DB6BF7BD0269FF" modified="2008-01-15" version="1">MPDVAPFRQYQLETAYDELFLGPNTPRPHYRLLSERLRELPPDELARRQQAADLAFLNQGITFTVYGRDEGTERIFPYDLLPRLLTAKEWDTIERGLAQRVTALNLFLRDIYHEETILKAGVVPRELVYSCRHFSRQMRGVSVPRDRYVSIVGTDLIRLPSGQFAVLEDNLRVPSGVSYMLANRLVMKRVFPQLFSSYGVRSIDHYGQALLATLRSLAPQGRSDPTIVLLTPGVFNSAYYEHTFLARQMGVELVEGRDLIVHDNVVYMRTTAGLRRVDVIYRRVDDEFIDPLAFRPDSVLGVAGLLNAYRAGNVALANALGTGVADDKAIYAYVPAMIKFYLDEDPILPNVETFLLSDDRQRQHVLNNLDSLVVKAVGESGGYDMLIGPHSTIEQRSQFRDRIIANPRNYIAQPTLALSKAPCFIDGKLESRHVDLRPYILFGDQISIVPGGLTRVALRRGSLVVNSSQGGGSKDTWVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B350</accession>
    <name>A9B350_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4883"/>
    <dbReference type="EnsemblBacteria" id="ABX07513">
        <property type="protein sequence ID" value="ABX07513"/>
        <property type="gene ID" value="Haur_4883"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4883"/>
    <dbReference type="eggNOG" id="ENOG5030VKV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1287369_0_0_0"/>
    <dbReference type="OMA" id="ELQFARI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4943-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732401" evidence="2">
        <location>
            <begin position="20"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="214" mass="23756" checksum="F5ED65697E1BE02F" modified="2008-01-15" version="1">MRLLVAAFLAFMLSTTGFFTFLPSAAKLTTPLVCNGGTIIPPASITRKSKFYCEKNGTQSLINPFLLLASGALVYTPLFYLALLLVKPKQTTLGGQQPKQPKPSKAVVDIQNQAQFARSLAGTAQVLDTEKGRHISSNGFRRDVEVILTLDVQRPDGSSYQAQSAWMVEELQFARIAIGNTIPVQIDADDPMVIYPSREFRHIKYSLWYTSNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E9</accession>
    <name>A9B3E9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1468"/>
    <dbReference type="EnsemblBacteria" id="ABX04112">
        <property type="protein sequence ID" value="ABX04112"/>
        <property type="gene ID" value="Haur_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1468"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OMA" id="GRMPRWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1490-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="25978" checksum="51F7F95B6AF35680" modified="2008-01-15" version="1">MPEILINLDHVTKSFQEAGQARLVLRDINARIQQGEVIALLGRSGSGKSTLLNILSGIDAPSSGRITINDIELGQLNEHQRTLFRRQNIGFVFQFFNLIPTLSVEENVLLPLELAGRLTAAQRERAYELLRRVHLFDRRHVYPDKLSGGEQQRIAIARALAHDPLLILADEPTGNLDATTGQEVLNLLDEMSRQAGKTLLMVTHSLEVARRADRLLSMVDGQLVEHSLAEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3G4</accession>
    <name>A9B3G4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1483"/>
    <dbReference type="EnsemblBacteria" id="ABX04127">
        <property type="protein sequence ID" value="ABX04127"/>
        <property type="gene ID" value="Haur_1483"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1483"/>
    <dbReference type="HOGENOM" id="CLU_1945814_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1505-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="129" mass="14185" checksum="B6CC531277462E4A" modified="2008-01-15" version="1">MVKLRQITSVLGILWQQLLCWAMVLHLGVGCPVGCVVNCEAQAQLKTPVIEQPIVLECTTEHSVIPSYAVEPSSPANTVVQLVAWFPMVLILPSFSRNLASQRQQWLIPLQQACSYIVLPTAPPPRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P4</accession>
    <name>A9B3P4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3806 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2978"/>
    <dbReference type="EnsemblBacteria" id="ABX05616">
        <property type="protein sequence ID" value="ABX05616"/>
        <property type="gene ID" value="Haur_2978"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2978"/>
    <dbReference type="HOGENOM" id="CLU_1935180_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3010-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024266">
        <property type="entry name" value="DUF3806"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12713">
        <property type="entry name" value="DUF3806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3806" evidence="1">
        <location>
            <begin position="59"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="147" mass="16664" checksum="43D4DAD9988D2EB8" modified="2008-01-15" version="1">MSQQQNIVAGLEHLAQHFVRSVQSQLGIELEYNHVAVKWLNTYIEQIRPNYEPEQVPPNLVQSLGAFLGACIIANYGGRWGHEHESNDWGIALPVQGGDIWVYPFNKVYKHIAAGEEHSVRMFYEAIPNLIDPSRNWGGPQDIELTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P9</accession>
    <name>A9B3P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2983"/>
    <dbReference type="EnsemblBacteria" id="ABX05621">
        <property type="protein sequence ID" value="ABX05621"/>
        <property type="gene ID" value="Haur_2983"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2983"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016728_0_0_0"/>
    <dbReference type="OMA" id="VCEEKHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3015-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07423">
        <property type="entry name" value="MPP_Prp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041780">
        <property type="entry name" value="MPP_PrpE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024028">
        <property type="entry name" value="PNKP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032390">
        <property type="entry name" value="PNKP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032380">
        <property type="entry name" value="PNKP_ligase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16536">
        <property type="entry name" value="PNKP-ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16542">
        <property type="entry name" value="PNKP_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04075">
        <property type="entry name" value="bacter_Pnkp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="180"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="PNKP_ligase" evidence="3">
        <location>
            <begin position="469"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="PNKP-ligase_C" evidence="2">
        <location>
            <begin position="795"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="854" mass="95830" checksum="F1C5868ADBFB5B5E" modified="2008-01-15" version="1">MELGIPELSLVVLVGASGSGKSTFAQRYFKPTEIISSDACRAMLTDDETDQSVSADAFDLVYTIAAKRLALGRLTVIDATNVQAEARKPLLALARHYHVWPVAIVLHTPERVCLERNLGRPNRDFGDFVVKRQIDNLRRSLRTLHDEGFRVVHSVTPEQVDSVEIVRQRAWSNRKVEHGPFDIIGDVHGCYPELERLLLELGYSINLTPGHNYGFTVTPPAGRRAVFVGDLVDRGPDSVGVLRLVMSMVETGAALCVPGNHDDKLARALAGRKVKQTHGLAETMQALAETDEAFRQAVRHFIEGMVSHLIFDDGKLVVAHAGMKQELQGRMSKRVREFALYGETTGETDEFGLPVRYPWAKEYRGEGLVVYGHTPIPQPEWLNNTVDIDTGCAFGGALTALRYPEREFVRVPAFAQYAIPKRPLEMNATQLSAQQAHDQVLDLSDFQGKLQISTSLISQINLREEQTSAALEVISRFAIEPQWLIYLPPTMSPSETSQLGSFLEHPAEALEYYRRAGVNEVVCEAKHMGSRAIVIICRDSEVARERFGVTGEQIGVCYTRTGRRFFSDPELETAFLQRLQQAISKLNWWESFDSGWFALDCELLPWSAKAHDLIQNQYAPVGAAATASMSAAQAALRQTVTRLPESVELQALIAHTQLRQQAVQGYVEAYQHYCWPVRSLDDLRLAPFHLLACEQRPLYDRDHEWHMQTLAALAEAEPRLLVATPYRLVDLHDQASVEQTIAWWQKLTAAGGEGIVIKPKQWVVQNSRGIVQPAIKCRGAEYLRIIYGPEYDLPENLERLRQRGLSGKRSLALREFALGLEALDRFVNREPLRRVHECVFGVLALESEPIDPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3S5</accession>
    <name>A9B3S5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3425"/>
    <dbReference type="EnsemblBacteria" id="ABX06061">
        <property type="protein sequence ID" value="ABX06061"/>
        <property type="gene ID" value="Haur_3425"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3425"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_16_0"/>
    <dbReference type="OMA" id="IYVESKM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3462-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038733">
        <property type="entry name" value="Predicted_DNA_bind_prot_RHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12651">
        <property type="entry name" value="RHH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="41"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="25188" checksum="81DBC89A9231091F" modified="2008-01-15" version="1">MTFPQTFELATTDKLTGLFTPDYFRFLVREQVLPAMHERVEPLSMFVLDIDYFLALNTESGRECGDAVLVAVAQVLKRVLPEQAMLSRYSGDEFAGALPELRIDDAFSLLEEVRRQVLAIQLDCLGEIKLSCSIGLAGYPGHGRDEVELVRQADEALYHAKTTGRNKIALPVADSRMITKTSYYTATQLERLAQLAKALKRNEASLLREALDDVIKKYNDRLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B456</accession>
    <name>A9B456_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ordered locus">Haur_4959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4959"/>
    <dbReference type="EnsemblBacteria" id="ABX07589">
        <property type="protein sequence ID" value="ABX07589"/>
        <property type="gene ID" value="Haur_4959"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4959"/>
    <dbReference type="eggNOG" id="COG0528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_0"/>
    <dbReference type="OMA" id="PIIVFDM"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="26623" checksum="7FCD93A35111BF55" modified="2008-01-15" version="1">MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGGPAIKAGMEPPQAHYMGMLATIINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVRHMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMAKNRVDGVYSADPRTDPKATKFDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKANTEAPATAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B462</accession>
    <name>A9B462_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4965"/>
    <dbReference type="EnsemblBacteria" id="ABX07595">
        <property type="protein sequence ID" value="ABX07595"/>
        <property type="gene ID" value="Haur_4965"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4965"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_528633_0_0_0"/>
    <dbReference type="OMA" id="WHIVQLV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5028-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="463" mass="50658" checksum="4D3B688686A6C339" modified="2008-01-15" version="1">MAKHTDNVQHSKPLNKRQRARWDQERKQSTRVLLIAAAAVGLAVLLIGIGLVIQKVIVPNKTIANIAGVEVTNAEYQQYRQIMQAQQAINLAQQIQQYAQYQLQGTEQFATDVTNYIAGLKDQNAPLDYAVLNQLISDKILENNAAAEGITVSDEELQQSLATKFAPANEVMNPVAPVTSTTGLTDTASLTPTPTSTPTLSEASNRVDSAVTTYFGTLREFIEETSTYGLATLPFDREAFKAFVLHQERLQLMRQKLGEKLVTEDQAIKEVYADAQQIFVTANITDPADPMTVTKWLQAKTKIDDIAAQLTDTASFTDVQILNTNDNATDNPTTGMQPLSQYAAFGITEPISTQEVGVIGKPYQSTQGWHIILVNQREWRPSQSDLTTKRDEAVNKWIEDKRAVSNVQRFPEPTATTVPPTIEPIPTTIPQPTTDPAAVTATPTGEAAPTSETAPTEAVTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A7</accession>
    <name>A9B4A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40 domain protein beta Propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0012"/>
    <dbReference type="EnsemblBacteria" id="ABX02664">
        <property type="protein sequence ID" value="ABX02664"/>
        <property type="gene ID" value="Haur_0012"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0012"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441929_0_0_0"/>
    <dbReference type="OMA" id="HANAAPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-12-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734547" evidence="1">
        <location>
            <begin position="29"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="620" mass="68948" checksum="1F55E3689004B8F7" modified="2008-01-15" version="1">MSRLKVRLTGLLSALVMVGTLFNGHANAAPWANRSAFVSPKFEEVWRRSDDPRVRDGRSLYWGFGPWFDYNEYYRESPNGLRRVQYFDKARMEINGINGNTDVTNGLLVVELVSGQLKTGDNAYDNAIRPAADRVPVAGDGYQTNSNSPTYASFAAVSTYNNNGYRDPDRRDQSIADAIDKSGNKSTRNDLRDAYKDQTKIVVYNATTGHNIPQVFWDFLNRTGPIIVNGQRTNGSIVDWTSAMGLPISDPYWVKATVGGVQKDLLVQLFERRILTYTPTNDAAYQVEMGNVGQHYFQWRYGHLGTPWNSSEPSLPIAFGSKRDGGAEWDTYAMNGDGSSQLLYASNDSKETVPYSWVRSWDPSKVKLFVDSRRGNGSNRQIWTVGADGTMTRVTYTDGTPTPPGVPYQGYVGTPSNDFNASVSPDGSKMAFVSDRSGKPQIFVSYTNGASQTQVTLDDCDHQTPSWSADGRYLYWASNCGTNAKYNIYRAELNWLADQPSNDYPYLSLELRNKVNLTNSTTSDNGFPRVSPDGTKIVFTSNRDGNSEVYLMNADGTNQTRLTNSSAEDGAPSWKLDGTKIAFDSNRDGNWNVYVMNTDGTGQAQLTNNSADDRWNVWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P7</accession>
    <name>A9B4P7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1569"/>
    <dbReference type="EnsemblBacteria" id="ABX04212">
        <property type="protein sequence ID" value="ABX04212"/>
        <property type="gene ID" value="Haur_1569"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1569"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037353_0_0_0"/>
    <dbReference type="OMA" id="SCHGNQN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1593-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="50"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29900" checksum="616175F4BFE66EEE" modified="2008-01-15" version="1">MVAKDMDWTENYTTIKALDARHDVWKHNAAVDGPFGPDLVPALKPDTLVLDAGCGTGVHLRTLIDRYPQARFVAMDTSEAMVAATRERCPEAEVVGGTITQLAWEDHHFAGTTCLHVLYHVPDIHQAVSELARVTQKGGWAVISTVADDAGQESLRLHNAACAEAHASEWQIEKLPSARFNTANGEQFIRPYFSQVTLYPRYAALYFTEVAAVLKYYTSMDYYQQIYRANQALAEQVVTKARQLVEAQLHAKGEFQISKNVGTWLAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P8</accession>
    <name>A9B4P8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1570"/>
    <dbReference type="EnsemblBacteria" id="ABX04213">
        <property type="protein sequence ID" value="ABX04213"/>
        <property type="gene ID" value="Haur_1570"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1570"/>
    <dbReference type="eggNOG" id="COG2045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070028_0_0_0"/>
    <dbReference type="OMA" id="GRIMVIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1594-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="240" mass="25726" checksum="E20A1F85995FB1DB" modified="2008-01-15" version="1">MVVIDFDPSSAQRYVNQGFNIVTVDVLRASSTITVGLARGAAEIIPCVTVDEAFALKQRHDAILVGERNAVIVAGFDYTNSPYDLEQTDLTGRIMVITTSTGTRLIAESMGAAHILIGTTINARAVANKMAQLGNQWAIIGAGTRGEFRPEDKVGCAVIAQYFLQVTGETTDSATQAFIDEFGSNSYEHISQSPSTIKLLSLGRACDVDFVLNHPDAFEIVPQVILKQAADAAYLSIVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q0</accession>
    <name>A9B4Q0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1572"/>
    <dbReference type="EnsemblBacteria" id="ABX04215">
        <property type="protein sequence ID" value="ABX04215"/>
        <property type="gene ID" value="Haur_1572"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1572"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_9_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1596-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="2">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="217"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="518" mass="56688" checksum="DC8E9590AF2D83D0" modified="2008-01-15" version="1">MILATTIKLLLYRYSNQTDMLIGTPVAGRLTTALESIVGFLANTLVLRTSLAGQPSFRVLLQRVREVALAAYAHQALPFERLLQQLGPNRSQSHLPVFQVLVTIQNSPEATLQLVDTKIVPIEFERGTAKFDLSFVFTETMNGLAGGIEYNTDLFDAATIERMIGHLNSLLLAGLSAPDLSIARLPLLTTAEYARYIAQSRGIASNFPSESCVLTLFEQQVARTPHALAVVQGHASLTYQALDHQANQLAYYLAALGVKPGTGVGLCIERTLMMVVGMMGILRLGAIYVPIDPSYPPERQAYMVANAGLVALVTQDQLASALQAQQPKLAIVALDTDWTAIACAPRVKLPLITADMVLYSIYTSGSTGVPKGTEVTHRNFVNLLNWYITEFNLGSDDRFLLVTSLSFDLTQKNVFAPLISGGTLYLYDAPQYDPHTITSLIDQHAITVINCTPSAFYPLVETTPDQAIVQLKSLRWLFLGGEPINLSRFHGWMQSSHYQATIINTYGPTECTDIAASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R6</accession>
    <name>A9B4R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3001"/>
    <dbReference type="EnsemblBacteria" id="ABX05639">
        <property type="protein sequence ID" value="ABX05639"/>
        <property type="gene ID" value="Haur_3001"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3001"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129810_1_1_0"/>
    <dbReference type="OMA" id="PLKILCC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3033-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="14045" checksum="BCE8F3BAD361AE47" modified="2008-01-15" version="1">MSDRVFLAHLRDQAEFVAGDGCHLRELLHPTQQPIRIGYSLAHAYVDVGCRTADHWLEQSEVYYIIAGHGTMVLDGQAHAIEAGSYYYIPPRCSQWLRNDGEQRLEFLCIVEPPWTAAGETITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B522</accession>
    <name>A9B522_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3523</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3523"/>
    <dbReference type="EnsemblBacteria" id="ABX06159">
        <property type="protein sequence ID" value="ABX06159"/>
        <property type="gene ID" value="Haur_3523"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3523"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_2_2_0"/>
    <dbReference type="OMA" id="IDDEICV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3560-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="4">
        <location>
            <begin position="83"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="30662" checksum="C679353FD0919D0E" modified="2008-01-15" version="1">MDNDDIPVGRILSRREALKLFSAVGAGMMLAACGSQNSTATTAPAATATTGTSAATAIPTATTAATSIASLPSCVVKPEMTVGPYFVDEQLNRSDIRSEPSDNSLRAGVPLTLNINVSQISSSACTALAGAMVDIWQCDAEGIYSGVTDAGFQTEGLKFLRGYQITDSNGDASFTTIFPGWYQGRTVHIHVKIRTTSNTNEAYEFTSQFYFDTALTNEILANAPYKAGSQRDTTNENDMHYANGGEQMLLSLTKTNDGYTAGFPIALDLSDAETGQADRFEQMQAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B558</accession>
    <name>A9B558_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3559"/>
    <dbReference type="EnsemblBacteria" id="ABX06195">
        <property type="protein sequence ID" value="ABX06195"/>
        <property type="gene ID" value="Haur_3559"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3559"/>
    <dbReference type="HOGENOM" id="CLU_1452587_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3596-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21492" checksum="ED172385A63ABBD4" modified="2008-01-15" version="1">MAWFRYWWLLLLLIGCIQTDQPLPTANQFAIYIFDQDAVPGLGSSAETAWPILQAVPLAQSAFTVTEDLLLSYHWQTQTITFTNPWGQTDRDAPGYMWNGGGSFVVIYNGQRLFGGKVVAAISPRRFDYPAMALSNDYILMENPELQGKLVYSFHPKSAVMYPPQSQFLAADPTITEAVKQHLREIGKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H6</accession>
    <name>A9B5H6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0149"/>
    <dbReference type="EnsemblBacteria" id="ABX02801">
        <property type="protein sequence ID" value="ABX02801"/>
        <property type="gene ID" value="Haur_0149"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0149"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1560834_0_0_0"/>
    <dbReference type="OMA" id="EFINTHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-152-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19866" checksum="397C2EA5FF3ABDAB" modified="2008-01-15" version="1">MELPSFIFPLLKRFRLPPRLHWLAANLINPHFLLGVAGIITDEQGRLLLFHHTYRRSHPWGMPGGWMSKGESPLETLEREVHEESGLHVRAERLALIGVTRDRPKFEFVVCGKLVGGTFQASREVDQMGWFAPDQYPALAPFHQHILQQWRDQPNHEVGWYEAPWIIAHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q9</accession>
    <name>A9B5Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cna B domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1649"/>
    <dbReference type="EnsemblBacteria" id="ABX04292">
        <property type="protein sequence ID" value="ABX04292"/>
        <property type="gene ID" value="Haur_1649"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1649"/>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_226136_0_0_0"/>
    <dbReference type="OMA" id="RIWNDAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1673-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="584"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="725"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="882"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1028"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1189"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1360"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1516"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1640"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1801"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1972"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2129"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2253"/>
            <end position="2370"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2374"/>
            <end position="2485"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2489"/>
            <end position="2600"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2605"/>
            <end position="2675"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="2761"/>
            <end position="2872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="953"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1443"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1898"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2058"/>
            <end position="2081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2990" mass="307078" checksum="F69D30B1BD439C86" modified="2008-01-15" version="1">MPSAGSVAYAAATIGGRAYRDYNANGVIDSLEPGISGVTVTLYNASNTIVGTTTTNATGNYSLTDSDPIYTGPYRVEFSDAPATVKSGPMGSNSGSTVLFVAGSTASANMGFNNPANYCQDNPTLVTNCFSMGRQDQAPSSTFHSIVSFPYTAGNTGNSPAPGVDSPAPTDLAFGAETGPTFGLAWQRSSSSLFASAVMKRHVGFGPSGTGAIYRITPSPRTVSLFLDLNTVFGAGTAGVDPHPNGTDLVHDSAAWDPVGKIALGDMDISEDQTTLWTINLADRQLYEIPIGLTPTAPSAAAIGRFAVPDPTDCAANDHRPYAVAVNEGLVYIGMVCSAQSTASAANLRAYVYQFNPSTDSFTQVLNFPLNHTRGCAVVPGCASANWNPWRTNFTVTNTNFGGEYVQPQPMLTDIEFDNGNMILGLRDRFSDQMGYRQNDTTAGSTTLYIGDSAGDILRACSNGSGWTLESNATCGGTTTAGAGTNEGPGGGEYYFRDNYPEHAEVSLGGLLQIPGKPDIVQTIYDPIFDSAQYFDGGILWLNNSTGNRTRAYRIYDSNTQPNTLAKAGGLGDLEALCDAAPIEIGNRIWNDTDSDGIQDADEAALANVDVRLYAPDGTTVLGSATTDANGNYRFSSLAGTSTPSTIFNIAGLQPNQTGYSIRVASVQAALTNKVLTAANTNSGTNSDVRDSDATITGADAIITFNTGVAGDNNHSYDIGFTTYSLGNRVWYDTNNNGTFDAGEQGISGVSVSLFADSDANGIPDSGTALSTQTTTSAGCYRFDGLAPESYVVRINPSNFTLGNPLAGYRSSTVTSGSANNDIDNDDNGIEGPILATDGVLSHVITLGGNEPTNETDLCSTDPAEPATGTNLSVDFGFFKLSVGNRIWDDANNNGLLDIGESGIDGVNVALYNSSNALIASTSTTGGGNYSFAGLLPGDYYIEVTPPANYISSTGTSGSATGTYEPAPDPDNNINNDDNGSTSGAIVSTAQLTLTPGNAGAQSATIVNNANGSTDDTTLDVGLFQPLAVGNYVWNDANNNGVFNGGEAGISGVAVTLYRAGSSTVLGTTTTNATGYYHFGLLGAGDYEVELDASNFSGAGVLVGYTSSTGTAGSPTGAYETAPDPDNNIDNDDNGTIVGTLGTTGVIKSAAITLAATSEPTGETNGSGDATVDANSNLTVDFGVYQPLSLGNRIWNDANNDGLRNNGETGIANVTVDLYMDRNSSGAIDAADAPTVANVQTNASGYYLFSNLLAGDYCVAIPSSNFTGAGVLVGFSSSTGAAAATGAFEPGLDPDSDNADDNDNGSVVGALGTTGSVQSACFSLAAGAEPTGEADSNGTGGASDANSNLTVDFGFYQLPSLGNLIWRDADNDGLFNNGETGIAGVNVDLYADDGDGSFDAGDSFIRQTTTSATGAYSFTNLLPGEYVVVLPAGNFTTGNVLENHVSSTGGGSDPASDPDNNINNDDNGTTIGTLGTTGVIASNAISLNAGSEPTNDGDTDPNTNLSLDLGVFPLGSIGNLVWYDTNNNGIFDNAEQGLSNITVTLATPGADNLPCTADDVVIGNQTTPASGAYNFAGLMPGNYVISFSGLPAGYVFTQPNVGGDDTIDSEANATGCAGIIALGVGENDDSVDAGAYQPLAVGNYVWNDANNNGVFNAGETGISGVTVNLYREGSSTVLATTTTNATGYYHFAVLSAGNYVIELDASNFSGAGTLVGYTSSTGTAGSPTGAYEVAPDPDNNIDNDDNGSIVGTLGTTGVIQAASVTLADNSEPTGETNGSGDTTPDSFSNLTVDFGVFQPLSLGNRIWNDANNDGLRNNGETGIANVTVDLYMDRDSSGAIDAADAPTVASVQTNASGYYLFNNLLAGDYCVAIPSSNFTGAGVLVGFSSSTGATSATGAFEPGLDPDSDNADDNDNGSVVGALGTTGSVQSACFSLAAGAEPTTEADSNGTGGSIDANSNLTVDFGFYQLLSLGDLVWDDANNDGLVSGGEMGIAGVTVALYADDGDGSFDAGDSFIRQTTTIAGGLYNFDQLLPGNYIVVLPAGNFTTGNILQGWASSTGGSSEPASDPDNNINNDDNGTTIGTLGTTGVIASNAISLNAGSEPTNDGDTDPNTNHSLDFGVFTLGGLGNYVWFDTNGNGIQDGTENGVGGVTVTLYTPGPDNQPCTADDVVIGSQITSGTGNYSFGDLQPGSYLVKFSDLPAGHVFTQPNLGGNPANDSDANQITGCSGLVTINVGTYNDTIDAGIYQLAGLGNYVWHDLDVDGIQDGGEQGIANVTVRLYIDNNTDGTPDGAAISSTFTGAIGDYFFGQLPPNSYLVEFVAPSGYFFTQQGAGSDPTIDSDADTTTGQAATVTLSSGDSNPNIDAGLYQLASLGDTIWYDTNINGIQDSGETGVNGLTVNLLNSSNVVIDTTTTVNGNYQFTGLMPGVGYYVEFTKPANYNFSQANVGANDAIDSDANPANGLSTLITLASAENNPTIDAGIYELASVGNLVWEDQDGDGIQDGTEPGVGGVIIRIYDNSNALVDTQTTAPTGVYSFTSLIPATYTIEFQQPVGMEFTTPNVGGNDTVDSDVDVGTGLTPAIDLAAGENDMTWDAGVYTPVSLGDLVWNDINNNGIIDGSEAGIENVAVDIYRDTNANNQPDTGEMVANTLTDANGNYLFTGALPGDYIVVLPSSNFATGAVLETYVSSTGNFGAQPTPFEPASDPDNDINDDDNGITFAGGVKSLVVTVLANSEPTNDGDSSANSNLSIDFGVFIPASLGSIVWYDTDANGQYTPSDSGVPGVIVTLYDINGTAIISTTTDANGGYQFTNLPPGSYLVGFDNLPPGFVFTHDDMGNDASDSDVDPNTGLSDIIVLVPGDNNGTIYAGVTTPNAIELADFSAIREAGNVVVQWTTVSESKTLGFHLYRSSDGNRANAMRVTSSMIAAQGRSGGASYRWIDSNVDDSSTYTYWLVETELDGTTNEYGPASTNGTQANSYRIFAPMTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V9</accession>
    <name>A9B5V9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M29 aminopeptidase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3114</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3114"/>
    <dbReference type="EnsemblBacteria" id="ABX05752">
        <property type="protein sequence ID" value="ABX05752"/>
        <property type="gene ID" value="Haur_3114"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3114"/>
    <dbReference type="eggNOG" id="COG2309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057697_0_0_0"/>
    <dbReference type="OMA" id="HQGREIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3146-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="40916" checksum="0051A230A57052CF" modified="2008-01-15" version="1">MADPRVLKMAHTLVNYSMKIKEGELVVLQSEPAAAPLVQAMYREILLAGGHPVAHTVMPGLSRILLNHGNDKQLQWISPYDRLGIETADVRIRIDAQSNTRELSQVDPERQSVFQKSRRELMGTLMSRTHAGDFRWCVTLFPTEGLAQDANMSLPDFEDFVYGVCFLNEADPIAKWQELHDMQAHLINYLQNKREVHILGEGTDIRVGIAGRSFVNCAGDANFPDGEFFTGPEETNVNGVVRFSFPAIYNGREVEDVQLTFEAGKVVKATAKSGQDFLEQMLNVDAGARILGEFAFGTNPNIKNYTRNILFDEKMGGTIHMAVGASYPETGGLNQSAIHWDMVCDLRQNSEVYVDGQLFQKNGTFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G2</accession>
    <name>A9B6G2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0213"/>
    <dbReference type="EnsemblBacteria" id="ABX02865">
        <property type="protein sequence ID" value="ABX02865"/>
        <property type="gene ID" value="Haur_0213"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0213"/>
    <dbReference type="HOGENOM" id="CLU_1658408_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-216-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="17101" checksum="458FA1EDA5B34040" modified="2008-01-15" version="1">MPNLIVNGREYRSVDEMPAEDRQLYQQTLSLLGDHDGDGVPDIFNQTGKVQSVNLNQQQINLTNGANDQLKQVFVDRDGNGIPDILEGQTNLGNAQSNFGNPQATTSSTTWKTAAPTADPLGSSPLPWNQPQQSNGFMLGLVVGGVVIGAALLIWLLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J6</accession>
    <name>A9B6J6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0247"/>
    <dbReference type="EnsemblBacteria" id="ABX02899">
        <property type="protein sequence ID" value="ABX02899"/>
        <property type="gene ID" value="Haur_0247"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0247"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_0"/>
    <dbReference type="OMA" id="HYDKEEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-250-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="32513" checksum="E5659B0CDA3F5F88" modified="2008-01-15" version="1">MFKIGEFSRLAQVSVRMLRHYDKLGLLIPNQIDQWTGYRYYSVEQLPRLHRIVALNGLGLSLQQIGELLNHDDLSADQLRGMLRLQEARLTAELAKKQAQLAEVSARLAQIEHEQEPWPYAMMLKSTAAEPIVSMRAIVPSLDQMGYYCHRLYASLYQQVQQQRIPILAQEITIYHNEEFIETDIGVEVAVSLAEHNMAQLPDSNIKFQTLPSLELAATLAFEGSFSEIHAAALALLGWVGLHNYEMIGPLREFHRSGPAHNAQGGIQEPAVIELQLPIKLRDNERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L4</accession>
    <name>A9B6L4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1680"/>
    <dbReference type="EnsemblBacteria" id="ABX04323">
        <property type="protein sequence ID" value="ABX04323"/>
        <property type="gene ID" value="Haur_1680"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1680"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024502_0_0_0"/>
    <dbReference type="OMA" id="RWKVIDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1704-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="5">
        <location>
            <begin position="19"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="568" mass="64619" checksum="9D847E1F432268A0" modified="2008-01-15" version="1">MAKMYPPSLGSNNEIPSSERLLYEIFQSQLDADFIVFHSVAWLGRGARGQLSDGEADFIIVHKAYGILVIEAKGGRIRYNANLPTDQQWQTIDRFEQKHQLKCSPFEQAKRSKHALWNKLKELPRFKQPKLLFGHAVAFPDITADFEILPPDTNQSTIIDSRHLTAIQPKIIKIYQQWQGNQRFESLTPATVDLIIQLLAPVISIDISLGSRINQYQAQLLTLTQQQFQTLNMLRRQRQALITGCAGSGKTMLALEKAKRLATNEAMNVLLLCFNRRLANHLKTLSSGIQNLQVYTFHEFCSTICSQYHINSSKPANIDEKTYYRYFLPEQAFLASDDLSEETKFDALIIDEGQDFAENWWDILTIFIKPNPIFYIFYDNNQRVYQESNTFPINQDPFYLDINCRNTQKIHRAVRYFYQGSDAETISAQGPEGETIEVLLYETPQQERELLGEILGRLHNQEQISAKQIVILTPYSPQNLNLANTTIAGYIISDKPRNPQQILCSSIQGYKGLEAPVVILAGLDERIDAGEVEQLQTILYIACSRASGHLIVLLPKSAPAKIRKAFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N0</accession>
    <name>A9B6N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1696"/>
    <dbReference type="EnsemblBacteria" id="ABX04339">
        <property type="protein sequence ID" value="ABX04339"/>
        <property type="gene ID" value="Haur_1696"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1696"/>
    <dbReference type="HOGENOM" id="CLU_2479071_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1720-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="87" mass="9734" checksum="77644C6E2A196C37" modified="2008-01-15" version="1">MKPWLRRTIILSGISLLLGAIFKEFSQPRGLRVGEGKVLGVPYSLRLPNGHDLRQRYWNAEGSPVAPPLLGVGFYPNIPALLRKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P2</accession>
    <name>A9B6P2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04351">
        <property type="protein sequence ID" value="ABX04351"/>
        <property type="gene ID" value="Haur_1708"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1708"/>
    <dbReference type="HOGENOM" id="CLU_1243904_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1735-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24442" checksum="097B05E6120140E9" modified="2008-01-15" version="1">MQHLVKTLVVPVDQQACETCCDQLAIYAERNQRITQQYLSPAIQNHLDACVGCSEYFAALDRSFTAVTGDLPVPQPDLSFLNQAPSWYEKVAAALAMVGKHIQISLNQSLLDGFAALQPAQPALRGENTQPLQLTFTPSIQPLREINLAIYPAEANFCRVRVQVQLHDREWPDLANINVHLIAPSGRRSTETDVWGEAVFGEVQAADVAGLTVEIELPTPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B751</accession>
    <name>A9B751_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Germane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3698"/>
    <dbReference type="EnsemblBacteria" id="ABX06334">
        <property type="protein sequence ID" value="ABX06334"/>
        <property type="gene ID" value="Haur_3698"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3698"/>
    <dbReference type="eggNOG" id="COG5401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_526551_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3740-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018911">
        <property type="entry name" value="Gmad2_Ig-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10648">
        <property type="entry name" value="Gmad2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00909">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732561" description="Germane domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="2">
        <location>
            <begin position="412"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="517" mass="54564" checksum="F539390EECEB6A81" modified="2008-01-15" version="1">MRSLKYISLALLLVACGGQSPATTTPAATTNLPAQATATIQTGSAATTIPTTVPQATGMPQATVATANQINLSAPPVDAVLTDSVRVAGTIVLTPFEKTLRLVIQTNDGNILYEGPINTTGEYGSSATFDVTVPIVAAASGPGVIKVIEDDMSGELPYRTIAEQPVQFTSTSAEPTPAEPGILIELTEPAMHAVVGNPLNFKGTLSAMPFEKNVVIEVYDSELHLLGQTSVIADGEYGSAGTFSGSINFQAPLSSRIGRIVAYTTSPKDGSVVGRDEATLTLPAWNGTGAYLAQPAPETSAFLPLHVEAVGLSSDTYTVRLRYADGTLLENTTQAYNGYLALSLMWDNAAPILPNQSAILELVKADGTVELTQNLYMQDLTSQPTTSVEVSWLAGEGSINGIRILPKTSSVASAALRELVWGPVGKDSAYSTAIPSPKIIADYTGDKTGWTGRVHLRSVRIEGDIAYVDWSREMRAWGGGSMQLESLQAQVDLTLKQFSQVKQVVMTVEGSEEVLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B795</accession>
    <name>A9B795_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3742"/>
    <dbReference type="EnsemblBacteria" id="ABX06378">
        <property type="protein sequence ID" value="ABX06378"/>
        <property type="gene ID" value="Haur_3742"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3742"/>
    <dbReference type="eggNOG" id="COG1089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OMA" id="KLAMEHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3784-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="4"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="35715" checksum="C235FEF7969E718C" modified="2008-01-15" version="1">MRVLITGITGPVGSFLADYLLTLPDLEIHALKRWRSDPRPIEHLQGKVTFHEGDIEDAFAMATLLRRVQPERIFHLAAQSYPSASWDAPVTTLRANTEGTLNILEAVRVTVPQARLHIACTSAQYGIVNPADVPIKESHPLRPGSPYGVSKAAAEMLGLQYHQSYGLHVVVTRSFNHVGPRQGDRCSIQTFCQQMAAIEAGQSEPVIHVGNLEPQRDFSHFSDVARALWLLLEKAPPGEVYNLCSGVATRIGDIVELVRRFGRVPIEVRLDPSRLRPVDEPILQGDNSKLRQATGWEPQIGMEQIVQEVLDFWRERYGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7A1</accession>
    <name>A9B7A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3748"/>
    <dbReference type="EnsemblBacteria" id="ABX06384">
        <property type="protein sequence ID" value="ABX06384"/>
        <property type="gene ID" value="Haur_3748"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3748"/>
    <dbReference type="eggNOG" id="COG3415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1967520_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3790-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14653" checksum="BBF58E8EA19952EB" modified="2008-01-15" version="1">MDRSSTLGGHHGITQCRREDGWTIARLATHFRVNRSTVFRWIQRDQPDDHSTAPKRHGRIVITKVYWAAVLAYRDANPHHGTQHIAHELHPQFPTANKATIWRILHAAGRIGPRPKNIAWLMPIGWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7A5</accession>
    <name>A9B7A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06388">
        <property type="protein sequence ID" value="ABX06388"/>
        <property type="gene ID" value="Haur_3752"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3752"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_354467_0_0_0"/>
    <dbReference type="OMA" id="PRIQSWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3794-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731950" evidence="2">
        <location>
            <begin position="24"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="773" mass="84174" checksum="93C2C3429C45F9B9" modified="2008-01-15" version="1">MKRARLLMFVVLAGLLTPLGVWARPVTPPQAQPQAPNTVNFFVDPNSFADTMVPGQSRQFAFQIQSLSSSNESANFTFAPEGLPPQITVNAIAPVTGVNPSDQVTVLATINIAATAPLQTYTFRIRVTATGNTTGVASSRIVDFLINVVAPTATPTRTNTPTATAPTATNTGTPGRICDGNGGTVNDKFEPNNTRSQARRIEVDVPQVHAICPVGDEDWLLFGGLEGKVYTIDVSQMVDGLDLSLTLYDSNGNQLAFNDDFPRNNDPSDIKPRIQSWRAPANGQYYIKVRDSAGRGFIDALYTVVLNSESYGPTPTLIPEICKDLYEPDGLPEIAPLIVVGEVHPDHRLCPRGDADWVKFFGKAGKVYSIFTSELSVGADTVMVLADRDGTTIIDFNDDYESGLDSRIDFAPFVDGFYFVQVKNVGDVGNQFIDYTLTFQIKTNANQGEPTMQPTATFEDDITPTFEDDVTPTSDPNRTATATGTATRTPTSAYPTPTTSSSNKLPNFDTRSNGKFADPAFNKVWAYADAPVASGQAVRSWLWGPSSGQARAEVYDQAPGGLRQVQYFDKSRMEISDFEADRQSQWFVTNGLLAKELIQGQIQIGDSNYVQRSPAQINIAGDLGAASAPTYASFSNLLGATSDRTGQFADQQLARSGKVSAYAGAATDAAKLVHYVPQTGHNIPSAFWDFVNRQGLVSQNGRTQNGQVMDWVFALGYPISEAYWAKVYVGGVEQTVLVQAFERRVLTYTPSNPADWQVEMGNVGQHYEQWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F9</accession>
    <name>A9B7F9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0280"/>
    <dbReference type="EnsemblBacteria" id="ABX02932">
        <property type="protein sequence ID" value="ABX02932"/>
        <property type="gene ID" value="Haur_0280"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0280"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684710_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-283-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="159"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="44086" checksum="E480F49E7F213601" modified="2008-01-15" version="1">MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRLSLTDNTGMIIQTLSDHASTYPLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTLDYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIAIHELQTPISILLGYIDLFERRVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTVVGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADGQITIQDYGVGISADALVQIARPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIASTVDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I7</accession>
    <name>A9B7I7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0308"/>
    <dbReference type="EnsemblBacteria" id="ABX02960">
        <property type="protein sequence ID" value="ABX02960"/>
        <property type="gene ID" value="Haur_0308"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0308"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053649_0_0_0"/>
    <dbReference type="OMA" id="AWEKNWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-311-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="206"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="380" mass="44037" checksum="AC8E594600BF2372" modified="2008-01-15" version="1">MLPLQIVPVRNARQRQQFIHFPWKVYRGANPDPLWVPPLLIERERFFNPKHGGFFAHGDVQLFLAQRGTEIVGTISAHINFLHNRTHNEHIGFFGFFEVLDDPEAAATLLQTACAWVRDRGYKAIRGPMNFSINDECGLLIEGFELAPVMMMTYNPARYVEYIEHQGFGKAIDLYAWIVDQRSYAEKGRGAKIERVAALAQAQTGLTFRKLNMRRFAEEVEAGWHVYNQAWANNWGAIHMTLAEFRHLAYSFKPFLDPEVMIVAEDQGRMVGLLIAVPDINIPLRYSDGRLLPFGWLTMLRRKREIDQMRVLIMGVLPEYRRRGIDAVFYREVRNAGLKRGYHTAEMSWILENNDVMNNTIAGLGGRRYKTYRIYEKKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K3</accession>
    <name>A9B7K3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0324</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0324"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM59">
        <property type="family name" value="Carbohydrate-Binding Module Family 59"/>
    </dbReference>
    <dbReference type="CAZy" id="GH26">
        <property type="family name" value="Glycoside Hydrolase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02976">
        <property type="protein sequence ID" value="ABX02976"/>
        <property type="gene ID" value="Haur_0324"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0324"/>
    <dbReference type="eggNOG" id="COG4124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024977_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-327-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006080">
        <property type="term" value="P:substituted mannan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022790">
        <property type="entry name" value="GH26_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000805">
        <property type="entry name" value="Glyco_hydro_26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40079">
        <property type="entry name" value="PTHR40079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02156">
        <property type="entry name" value="Glyco_hydro_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00739">
        <property type="entry name" value="GLHYDRLASE26"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51764">
        <property type="entry name" value="GH26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH26" evidence="7">
        <location>
            <begin position="48"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="6">
        <location>
            <begin position="585"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX02976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="694" mass="75337" checksum="2AE89024A876850E" modified="2008-01-15" version="1">MWSNLSRSRSLLTIALLGVLLGSLSLLPTHTTKAAITAYQAADPNLAPYAQNVLDRFVQYKGQYWLGGQQEVHWDNSRKDEMSNAVFARTNPQRYPALRGWDFPIGGALPNDGQWMIDAIISDWTNANVIPTISQHWTPLASQGTNHQDMFTVVDIDRMFVDGTTERTNYLIWLDNIADDLQQLEDANVPVLWRPYHEAGGGWFWWDKDNGATNYRRLWDDMFTYLVTTRGLHNLIWVWTPGVKGVSTAWYPAGQADILGSDVYNETSGNYVSWYEDLGRFSQTKIKALSETDYMMDPALLSSAPFAYFMIWHTDMFYRNTDSRIQSTYAHWATLNRTNVGQIWNGTLGIAPTATPGTPTPTPIPGIVVSDFEDGTLQGWTGTNLVSGPTVNNEWAANGQRSIKAQVNLAATPADIRLAQALDLTGQSRIQIRLSAQNVGSGLSAKLYIKTGSAWNWKDSGTVLIDSGISLLTIELAGVPDINQVRELGVEFNALTGNSGTATIYADYLTVGVVNSNQPTPTTGPTATATRTPTQAPTATPTNIPTATRTPTQGPTATATTIPTVTPTNIPTATRTPTQVPTATPTSTGGACKVDFKVTSQWGVGFIADVTVTNLQPSALNDWNVKFNFPSGQTISNLWNGTLSQTGSAVTVTNAGWNGYLAGNGGTANFGFQGVGSVPILPSNSFQLNGVTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T5</accession>
    <name>A9B7T5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1820"/>
    <dbReference type="EnsemblBacteria" id="ABX04463">
        <property type="protein sequence ID" value="ABX04463"/>
        <property type="gene ID" value="Haur_1820"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1820"/>
    <dbReference type="eggNOG" id="ENOG502Z7KY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124273_0_0_0"/>
    <dbReference type="OMA" id="FCDRRYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1848-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025352">
        <property type="entry name" value="DUF4256"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14066">
        <property type="entry name" value="DUF4256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="21207" checksum="43AC32332B90F5AF" modified="2008-01-15" version="1">MDHEKILLPEQREMLITDLQVRFSQHMSRHVGLEWAKIQAKLEQQPAKLWSLAEMERTGGEPDVLAYDPQSDSYLFFDCAAESPAGRRSACYDRAAQTSRKAHPPAHNALDLALAMGIELLTEADYRRLQTFGAFDTKTSSWLHTPSEIRSLGGAIFGDRRYNQVFVYHNGADSYYAARGFRGLLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B807</accession>
    <name>A9B807_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.85" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3304"/>
    <dbReference type="EnsemblBacteria" id="ABX05940">
        <property type="protein sequence ID" value="ABX05940"/>
        <property type="gene ID" value="Haur_3304"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3304"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_0"/>
    <dbReference type="OMA" id="TCAHKAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3341-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="1">
        <location>
            <begin position="3"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="35320" checksum="220826DB5F305628" modified="2008-01-15" version="1">MTRLCLIAGDGIGREVVQAARQVLEALAVPAEFVEAEAGWETFQRTGNALPEQTLAAVQAANSTLFGAVSSPSQRVAGYRSPIVGMRKAIDLYACVRPVQTPPLANARAGVNLVVVRENTEGLYSGQETREGDERATAQRIITRQASERIVQWAVQYAQRTGRRKITVVHKANVLRETCGLFRETALRVLSDAPDLQVEEMLVDNAAYQLARAPERFEVLVTTNLFGDILSDVASVWGGGLGLAASANYGTRTAVFEPVHGSAPDIAGQGIANPLATLSASVLMLEFVGLNSYAERLQTAIQAVLANGPYTPDLAGAATTAEVVQAVIDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8F1</accession>
    <name>A9B8F1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl-CoA acetyltransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3870"/>
    <dbReference type="EnsemblBacteria" id="ABX06504">
        <property type="protein sequence ID" value="ABX06504"/>
        <property type="gene ID" value="Haur_3870"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3870"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035425_4_0_0"/>
    <dbReference type="OMA" id="FQKYGDQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3912-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="384" mass="39195" checksum="44A79706E62AB862" modified="2008-01-15" version="1">MNQVFIAGTACTAVREHYDRSLLDLALEALHGAVGSLDPSLIQALYVGNALGDTLSEQSQLGAYIAGAAGLNCEAVRVEAAGASGALALRQGYLAIASGQADVVVVLGVEKATDKLDAALQAALALGLDGELERALGLTLTGAWALLMQRYLHEYQLPATAFAPFAVNAHANGAGNRHALYRFAINAQKWANAGQIAEPLNMLDCSTVADGAAAVVLVSQRYAREIAQPIAIVGSATSSTNVALAQRPDLLWLEAAAASGNNALQQAKLKRDAINIIELSDPHGIAAALSLEALGYAERGHATQLAAEGVIAKDGALPLATAGGYKARGDVGGATGVYQVVELVAQLRGQAGANQIANAKTALAQCLGGVGATAVTHILQVAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G7</accession>
    <name>A9B8G7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger SWIM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07631">
        <property type="protein sequence ID" value="ABX07631"/>
        <property type="gene ID" value="Haur_5001"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5001"/>
    <dbReference type="HOGENOM" id="CLU_1523134_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5064-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734628" evidence="2">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="176" mass="18629" checksum="0EB60DBEC0F62B3B" modified="2008-01-15" version="1">MQTVIQTAMLTHFGQLTAAITMAAPTPALHHSAALLLARCDEIVPNHCAPTSITATALKPIPPSSPLATLLQSDTTADDRWCFRVQQALLIAGDCSRRQLYEAVVLVLGQQVSRSDATTFTVQGSKAYTVTLANGIDHTEGFTCQCKGFWSHGGGQLCKHVLAAALIALDPEEGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8M0</accession>
    <name>A9B8M0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07684">
        <property type="protein sequence ID" value="ABX07684"/>
        <property type="gene ID" value="Haur_5056"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5056"/>
    <dbReference type="HOGENOM" id="CLU_1803543_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5118-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735534" evidence="2">
        <location>
            <begin position="35"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="14684" checksum="CA558050B40D978A" modified="2008-01-15" version="1">MTDSPDHPTKHRPWIQRTLVVMLSLALGSSALVAAQSPATTTTPHTTLPLYEAYLKASNTDAGDGFGLSIAVDGDTIVVGAPFEDSAATGINGNQADNSATNAGAAYVFVRSGTTWTQQAYLKASNTDAGDEFGAAVTITGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N8</accession>
    <name>A9B8N8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WYL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07702">
        <property type="protein sequence ID" value="ABX07702"/>
        <property type="gene ID" value="Haur_5074"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5074"/>
    <dbReference type="HOGENOM" id="CLU_1308722_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5136-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="145"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23155" checksum="60F901C8F7D9F178" modified="2008-01-15" version="1">MRLRQVMLVEGRAEALTVLEQQRGMQGGVQAGWTATHRVIPAGAAAQVARAVGLPSPRQPAPPREVETLVLALRIAAQQVPRYATVFQEQAQQLLADLSFAQRCVIDEQWEGLHSSLTPPLATDAEPLAVGHEPQAAITVEQARQAVREAIRSGQTLTVRYYTPSAHRITTRTIRPLELTSTGVRGWCELRQEERAFRFDRILAIAAHMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8V5</accession>
    <name>A9B8V5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Resolvase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_5141</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07769">
        <property type="protein sequence ID" value="ABX07769"/>
        <property type="gene ID" value="Haur_5141"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5141"/>
    <dbReference type="HOGENOM" id="CLU_010686_13_0_0"/>
    <dbReference type="OMA" id="RIIYHRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5203-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4 5">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15130" checksum="03CA6965D9D73EB6" modified="2008-01-15" version="1">MARIGYARVSSVGQSLGTQIAKLAACDKIYQETQSGTTAKRPQLAACLEYLREGDTLVVTRLDRLARSTYHLCQIAAELTRKQVDLHVLDQQINTHDATGRLVFHMLGAIAQFETELRAERQMDGIRLGSRLWET</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y1</accession>
    <name>A9B8Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07795">
        <property type="protein sequence ID" value="ABX07795"/>
        <property type="gene ID" value="Haur_5167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5167"/>
    <dbReference type="HOGENOM" id="CLU_1822679_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5229-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15250" checksum="EB1F54C5A051ABF7" modified="2008-01-15" version="1">MPTTITLIIDMPMLHEDLGRTLMRSAPTSLSIRPIPTGRRGGAFYTIVALDETIPLVMILGATLLPYLRNHLHTWNTTHPANPIAATIDVVAEPETVLQSHGLTALPTSMDGLLASLAATAPDQQIAYRIRLHPTNDQPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B982</accession>
    <name>A9B982_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5269"/>
    <dbReference type="EnsemblBacteria" id="ABX07896">
        <property type="protein sequence ID" value="ABX07896"/>
        <property type="gene ID" value="Haur_5269"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5269"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061144_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5331-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="305" mass="33066" checksum="CDE785238D01E891" modified="2008-01-15" version="1">MDHRNESGRLMGRMRVGGWMGVGMVGLVAWLLALPAVYPAGAATDPPLHGGTNTGADRPRRSVPTPILDRGWDYAYHQAMGVDPQVELVPGQTYPFVHAAHGVIDQTTGVTISVIRPAESMTDLSILYGTGIPNNVAPYQSCDLEFAFVFVGSFRGQPEQSHFIEQCMIPPYPSGTRVWYRVYGAPSVGEDPFYRFLLPGLGLEPCTQINILGQCIHPSLLFPELHLPYNFYDVGNASPTPTNTPTETPTTTPTNTPTETSTPTNTPTNTPTETPTPTSTPTSTPTATMTPIPPRSTVFLPWAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A8</accession>
    <name>A9B9A8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07922">
        <property type="protein sequence ID" value="ABX07922"/>
        <property type="gene ID" value="Haur_5295"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5295"/>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_335804_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5357-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="849" mass="92652" checksum="4B9587673752C48F" modified="2008-01-15" version="1">MLIPESATIPISLRSWLMRDESIYLYAHRIPTDPPTAWLWTLIAQLIVQHLPDHLPTLPPADAPYPTVWKTWVALLNRLASTTKPITIVLEGMDHWERPWEQLPVVLPAGVVIIMPIPLAPNAMPEWPVNMVIMPIPSDPIPTAIRDGIDHLEAHARTDPSQWKTILCPLLACLHGAYAPLTVTAIATIFAVPVETVEAAVAWIPSILAVTLDGVLCLMPGLAEIPAWNRLFPASVLGDGHRRLAAWCGQAEAVIGQDTVDDAAFEQRRYASHAFLMHLTGAQQERQIGLLLDAGVYGLAKIQGDGTRDGVIADLMYGVVLQTPSPSIPLDVVLVRAWQYRLLALRLQTAVEETNHDRWRGMVELGFGTEAMHQIAQLPHQSERIAAWSAVLAVGNTVQRQAIYAQIVAAIPHGPIDPTVLRSILTSAMEHGDWAILEPLVSAYPNAWQRGMMMLTIAQAAARADQHRIARQWLLRVQTAIPLDLLPVQQLAMVGLVAETAVVIGDRETARQIADRMDDQRFRSHIQRRIIDAAIAAGAIAEAQTIVQTIPNPASRAAGLQALAVDAARRGAWDTAHQSVAAIVDHPIADATRDALVQAAIDQGRLDDAALLAQSIDEAPSKVHALTALGTAYAQRGDWMQADTILRILDTTDGDQESALLAMVVAAATTDNGAKVHALLPLISHVPGLYQAIVAAHEQGHHALRDQVIQYMLQYAQTFIDDQEQASFLHNTLFLLVHVRVYRFMPPFLAAIRDPHARAWMGTDLTMRAMGVPAPPLRQGRGSIDGMDDTMALVNPILAAWIDAPTPSALWARLSMVHPLLAAYPDLGAALLATIPWVDAMVARLTRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD2</accession>
    <name>A9AUD2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase probably involved in cell wall biogenesis-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0400"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03051">
        <property type="protein sequence ID" value="ABX03051"/>
        <property type="gene ID" value="Haur_0400"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0400"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_697985_0_0_0"/>
    <dbReference type="OMA" id="HSINGMF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-403-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="PTHR12726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="388" mass="44870" checksum="EBCC14B460B38BA5" modified="2008-01-15" version="1">MRWLAWWYLLDRCWRWLVIRRFFAKHQPPAPKHWPSIDLIQPLTHGVFDLAKTLQQRLDLRYAGQLQHYWVIDQADNQTLAVCSALQKKHPEQHITIIQVAPDWGQRASKLVKLQAVLAQANSEIVWFVDDDVSLPLDGLSQGLPYLFQPQVGAIFGLACYVNWHNFPSALMSNFVNANALPSYIGLAALTEPYTITGHQFALQRSVFEQIGGLSGMYGRIDDDHELARRVQAHGLRNLQMPLIYQVDNYFVNLPAYFQQMQRWFTIPRVLMLPHLSQYDQFVTILSSLAQPIPTILALASMRQPKLRPWLVACLLAQLSLQGWQIRRYCQTKVPWWAWPLSIIGTLIDPLLMLWGLLGDDTIVWRGERIRLRHSASAQWLGKEQDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUH4</accession>
    <name>A9AUH4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-trcl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0442"/>
    <dbReference type="EnsemblBacteria" id="ABX03093">
        <property type="protein sequence ID" value="ABX03093"/>
        <property type="gene ID" value="Haur_0442"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0442"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115791_1_0_0"/>
    <dbReference type="OMA" id="ECENEFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-448-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026363">
        <property type="entry name" value="CxxC-x17-CxxC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025306">
        <property type="entry name" value="Zn-bnd_dom_prob"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13451">
        <property type="entry name" value="zf-trcl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04272">
        <property type="entry name" value="cxxc_cxxc_Mbark"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-trcl" evidence="2">
        <location>
            <begin position="2"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14224" checksum="20A44FBF3811F93B" modified="2008-01-15" version="1">MNCRDCGNEFVFTAGEQEFYSQKGFDNEPTRCSNCRQARKQNRGGGGYESSSRGGGGGGYSRNSYGSDRGGYSSDRGGYSSDRGQREMHTTTCSSCGGPAQVPFVPRGDKPVYCRDCFQSQQSSSRSNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL8</accession>
    <name>A9AUL8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1902"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04545">
        <property type="protein sequence ID" value="ABX04545"/>
        <property type="gene ID" value="Haur_1902"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1902"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018668_1_0_0"/>
    <dbReference type="OMA" id="THQGAEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1931-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cellulase" evidence="3">
        <location>
            <begin position="37"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="40810" checksum="F6D51FDF07C5DDB6" modified="2008-01-15" version="1">MTTLSNPKTAISDTRFAKLARGINLSHWFAQDYTNQYSLEHLRTYNTEADIALLAKLGCSHLRFTLNPVVLLNESNPTELNPSYLAEVDRVIDLMLAHDLAVIVDLHPEDDFKQRLFSSPSLVKIFASFWQRLAAHLAQRDPEMLFLEVLNEPVVTDAQQWAFVQAELLAAMRAGAPNHTLIATGHKWSSITELLELEPLADPNIIYNFHCYDPHTFTHQAATWGAPYWPYLEYLPYPSSPEALAPIVATIDDDVARDAAINYGNERWNIDTLREWIGQAAAWAEQHQVRLTCNEFGVYRFKSKPEDRAAWLHDLRSVLEEFNIGWTMWDYAGGFSVVNQLSGQREIDALTVEALGLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN6</accession>
    <name>A9AUN6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1920"/>
    <dbReference type="EnsemblBacteria" id="ABX04563">
        <property type="protein sequence ID" value="ABX04563"/>
        <property type="gene ID" value="Haur_1920"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1920"/>
    <dbReference type="eggNOG" id="COG1337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023344_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1949-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023825">
        <property type="entry name" value="CRISPR-assoc_RAMP_BGP1436"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03986">
        <property type="entry name" value="TIGR03986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="664"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="689"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="719" mass="81902" checksum="1D5EC8D11D91EDC4" modified="2008-01-15" version="1">MKKHIRKIENDNRIAIAPYNFVPLPDRVITLDPDKDKIDHARYANNRNTGQIDCKLTTETDLYIRSGLTASEFAASQQNAQPVDPPQRASLEELIAVLQTNPKNKPQFFSTTNSNQPVIPASSLRGMIRSLVEIASFSKVGWVSDNPQFFFRAVADNKRSIGIYYKNKIKNVQAGYVCKIGDKWVIFKAKVINGKNFCWYKPWNSLNDDIIREIGISMFNDNDFSIGYKPIYFDNPNFDEHRKFITDRISVRNNLNNKGFITNSGNMLETGEEGNSNRKNYCIIFEKSQEHKYTINDQAIYDYCNNLTEFQKLLGEKGCLINGRPIFFIEPTQEKGEVIYFGHSPNFRLAYRRDDLDKAVSALDCLPSEISSNLNIPDLAESIFGYVRQTKTNDQNRAAVNNSLSQEGEKKQALAGRVFFSNAHLSPEQGDVLKETHIPQILASPKPTTFQHYLVQIDPAQDQLAHYSTKGAVIRGRKLYWHQQPSNAYTTDIKQVEKAQTQYTCITPVNPGTTFEFTIRFENLSDVELGALLWVLDLASCAGKYRFKLGMGKPLGLGSVAINYELQLTDRKQRYQRLFARDGNWETGFEPSSQATQTKAIDAFCKFIDDNLGMDIEETEQIQQLRSLLAYRNGEGILFAGFSSGEDSALRYMEIERNTKMSFLPSQEDKKNKEAMINEYDDRRVLPKPSQVAPPPPRELPRPPIADDPIKVTVRRVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU8</accession>
    <name>A9AUU8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3902</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06536">
        <property type="protein sequence ID" value="ABX06536"/>
        <property type="gene ID" value="Haur_3902"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3902"/>
    <dbReference type="eggNOG" id="COG2261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160040_0_0_0"/>
    <dbReference type="OMA" id="RMGMFAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3944-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9115" checksum="B99AA664338E8595" modified="2008-01-15" version="1">MLSLIAWLIFGALIGWVASKIMNTDAQQGAVLNIVVGIIGAFIGGFLINRDVTGNVFNLWSVFTALIGAVVLLGIVNLFQRGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV22</accession>
    <name>A9AV22_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3978"/>
    <dbReference type="EnsemblBacteria" id="ABX06610">
        <property type="protein sequence ID" value="ABX06610"/>
        <property type="gene ID" value="Haur_3978"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3978"/>
    <dbReference type="eggNOG" id="COG3464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2206408_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4020-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="12217" checksum="03367AB7C7915E93" modified="2008-01-15" version="1">MTMPVQLELHLQRFRCPNRRYLRQTFVEPLPTLALPHAHRTTRLARTQQRFALALGGEAGVWTLNHLGITTSSDTLLRLIRAFEPAVAEAVTHGGIDDWAYHKRYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV98</accession>
    <name>A9AV98_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0528</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0528"/>
    <dbReference type="REBASE" id="16514">
        <property type="entry name" value="M.HauORF528P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03176">
        <property type="protein sequence ID" value="ABX03176"/>
        <property type="gene ID" value="Haur_0528"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0528"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006958_2_2_0"/>
    <dbReference type="OMA" id="HPFTPRC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-537-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39808" checksum="4C17258398FEA910" modified="2008-01-15" version="1">MVGAVIDLFCGVGGLTHGLILEGFGVLAGIDNDPSCKYAYEQNNRTRFIEKSITEVDGRELNALYPNNQHKILVGCAPCQDFSQYTKKSRTGTKWQLLTEFSRLIREIEPDIISMENVPEVRTFNRGEVFNNFIQALEQLGYHVSHSVVHCPDYGIPQQRDRLVLFAAKQGVIKIIPPTHTPENYRTVREVIGSLPPITAGGHWEGDSMHAASRLEDINLRRIQHSVPGGTWADWPEELIAECHKKESGESYGSVYGRMEWDKVAPTITTQCNGYGNGRFGHPEQDRAISLREAALLQTFPRSYQFAPEGQLKFKTVSRQIGNAVPVALGRVIAKSIKRFLEGLHERQRVRIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE9</accession>
    <name>A9AVE9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1997"/>
    <dbReference type="EnsemblBacteria" id="ABX04640">
        <property type="protein sequence ID" value="ABX04640"/>
        <property type="gene ID" value="Haur_1997"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1997"/>
    <dbReference type="eggNOG" id="ENOG502ZHMN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1882893_0_0_0"/>
    <dbReference type="OMA" id="AWYHYLA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2026-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15593" checksum="32F94029DC876FF2" modified="2008-01-15" version="1">MGNDFMYGDASIGEITLDRWKLMRQLLRILIEYLNQAMLRSNISGIRNLTVSPHAPSIPPLPIPAIDQPPRGALLFAAIFEDRSDWLNEIEVLDPAEWRRLFAWYHYLAARDGALDLFEPTMQGLYRRTSALEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH0</accession>
    <name>A9AVH0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2018"/>
    <dbReference type="EnsemblBacteria" id="ABX04661">
        <property type="protein sequence ID" value="ABX04661"/>
        <property type="gene ID" value="Haur_2018"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2018"/>
    <dbReference type="HOGENOM" id="CLU_690330_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2047-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735250" evidence="1">
        <location>
            <begin position="29"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="43067" checksum="EFDDF0DF31407CAC" modified="2008-01-15" version="1">MSTRRFSLRMLSLLTLLSITILPAAATADFDLLDSQNVTAVDNVSTANGGTFNGGRVYVAATKQTSNNNALRINGIYTDANGIISTNFVLTEGPIHDVDVTEYRDNIVVVAAITSGHIKLIAFKTNATGANRLERLGDTAGVATIPVSTNGVHVIRVGPTPNPSIVSAAYLSDGRARFDVWTLSTDGQNFTHQSTKISAGQTGRLAMSADYIKSSRNFAMAAQDANGHMIVTLWQVDVHGNLLKLAQSARGVVDFMDITLSGNRIYTAATNTDSPLATAEVARWTVAASESGAPLPNILDYKDEATLPIRFSGRIQLVDQGNEVVVIGQTGSETDDDDWQTMRFFTYTFNGSTLSLASPIKELPNQADGFDVVKNDSRFFLMIDGFVNSQDSHQVWQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS7</accession>
    <name>A9AVS7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4045"/>
    <dbReference type="EnsemblBacteria" id="ABX06677">
        <property type="protein sequence ID" value="ABX06677"/>
        <property type="gene ID" value="Haur_4045"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4045"/>
    <dbReference type="eggNOG" id="ENOG5033F64">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2571717_0_0_0"/>
    <dbReference type="OMA" id="MFIKVTN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4088-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="83" mass="9494" checksum="ACC999C71ED40ED1" modified="2008-01-15" version="1">MGARIVILHLSGEDPIVAEMEEDPQPTDAFIRVSNMRRRDGKDVPYIGGGVQSVIYPWHRVTFIEMMVSEEERGNVIDFFRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX6</accession>
    <name>A9AVX6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0566"/>
    <dbReference type="EnsemblBacteria" id="ABX03214">
        <property type="protein sequence ID" value="ABX03214"/>
        <property type="gene ID" value="Haur_0566"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0566"/>
    <dbReference type="HOGENOM" id="CLU_2154880_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-575-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="11937" checksum="ED098D18DD782B70" modified="2008-01-15" version="1">MTLTQTLLALMIVAVLSFVIGFLKSIAPKAAEALHTWADANLGAEQRDALYGAVKAGLRAAEAHGLKAEDLLAKAVQVASGYLTQYGLPFSETLLRDLVMAEKYKKTQESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY1</accession>
    <name>A9AVY1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0571"/>
    <dbReference type="EnsemblBacteria" id="ABX03219">
        <property type="protein sequence ID" value="ABX03219"/>
        <property type="gene ID" value="Haur_0571"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0571"/>
    <dbReference type="eggNOG" id="ENOG5032SFE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129219_0_0_0"/>
    <dbReference type="OMA" id="EMQANES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-580-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="19176" checksum="BEF44006616226C6" modified="2008-01-15" version="1">MIINQAMLWRQFDTTITNLEQALNTCPEHLWERQLWPDEPNQWVAAGFSRFWYLAYHTLFWLDLYLTGAEEGFMPPAPFDLVEMQANESLPRTYTRAELLEYLAHCRQACQTTITNLSAEQALRNCSFPWGQVPFGELLLYNLRHVQEHAAHLHMFLGMQASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW63</accession>
    <name>A9AW63_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulator, Fur family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2073"/>
    <dbReference type="EnsemblBacteria" id="ABX04713">
        <property type="protein sequence ID" value="ABX04713"/>
        <property type="gene ID" value="Haur_2073"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2073"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_6_0_0"/>
    <dbReference type="OMA" id="HAYIRIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2101-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="17169" checksum="09A60B0A41E37589" modified="2008-01-15" version="1">MQHHLTTGVAEHWLVGVEQSFRQAHLRWTPPRRAIVAWIAARSVPFTAEDLVADLARSSRATSYRMIEWLRGAGWITRLHSDPRQHAYIRIGPGHHHHLLCIGCGMTRIVQACTIDQSLERMIAGTDFAIQGHVLEFFGLCKQCQHECVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC1</accession>
    <name>A9AWC1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2131"/>
    <dbReference type="EnsemblBacteria" id="ABX04771">
        <property type="protein sequence ID" value="ABX04771"/>
        <property type="gene ID" value="Haur_2131"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2131"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_351190_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2159-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="801" mass="90552" checksum="DB965B4A68456D19" modified="2008-01-15" version="1">MDTIEQQLELLPRLWRYSLLRTSLTAHADRWPDELYVMLAIIGRLPEALAQINVCAYPERQVLAWARVIKYAEPQVQLQLLQRIEHSIRSIRDPEDQTFALSCLGLAYAEAGIPNATYPIYQVIDRPNLTVQGLLLQANRLASQGLSDQAYLLFDELFMTIFAMPQYEQLYQLMLLVQSAKRAGYNSLCERIIQSLYVPHEAPTFNSAIQELAKAYAAYGDFAVAHQAIQLIKQPRSFIHAARQVAVIACEKQIHTHTASLLQAAHERVKQLEDIDEHIYLLGQLAIPARQAGLIELAQTLMDEAFHKLIGVQHQYPPVATRLLIQSYQSQHALADALAIIPFLDNPQAHDYVLGNIIECYLNDNDLTNAHLLLKLFKPHEQTYVAAASNLLIKAGAQGLIELVWRLYWDVMAISKAINDHVNHRNYFVYVACNLATEASTHGLTVLTPRLYSEAIQACTTVDHGYTRLRYLKDLVLAQMKHGLVASFPNLLASLRLGATQLEINTALNEFLCPIAVVYAEQGNYSAFDDWFNYAHTQLKNSTQTDHKALVSGYRTLIKTYRTSASDWMNSAFLAAVLPRLQVIANTTHLASAKNLLINIYADYASEGHPAFLAQAYEMAITIEPIADRLNALKSLAKVYAKVNDGPHLRAIIAEMIELELDDLEFESIALVCAKQGDFAYAQELLARQEPAPWKDEVLWYLIAKLIQTNQVATACQLIPSLSEGYKQEREFQKIITYYLERQQLAEIGQIVQDVWRNCMSDTELWQLSTIIVPLIPHYPWLGIAVLDSVPWVEQQLARLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC2</accession>
    <name>A9AWC2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2132"/>
    <dbReference type="EnsemblBacteria" id="ABX04772">
        <property type="protein sequence ID" value="ABX04772"/>
        <property type="gene ID" value="Haur_2132"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2132"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2160-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="26"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1430" mass="161037" checksum="1D008B7E126657A2" modified="2008-01-15" version="1">MHNQILQESANQRESARLLQLRLTGFVGREAEQAAIRGLIDQTRPSGGYVLVTGEAGAGKSSLIAQLIVSAGLAQTPQHFIALTPGRAYQLDLLRSIVAQLMLKHDLVINYFPADSYPALRLEFGQLLQTLSARGISETIYLDGLDQLQPEVDGTRDLSFLPLQLPSGIVMVLGSRPNETIASLALEHGVVYQVPPLREQDAVGRWQQVQPTLEPVRLHGLAQAVKGNALLVELAANVLRHTTSAELLPLLDHASADATNLFRLSLGRIEQAAPHHWQSLIRPLLAVLLVTQESLELAVLAAILEQPTATVGEALALMSDWVSVAADQRVALRHLLFHDFLIDHEFAAAERRGWHGRMAAWCGAALDQIWHDSTESVEQARRWYARQHYITHLDCAEQWEALWQVIDAGEYGEQKVRFEPSTRLYGLDLDRARESVIAAGQSLEQQLELLPRLWRYSLLRTSLTAHADRWRDYHFVMLAMLGRVSEALAQLDICSNQVSQVRIWSQLLPYLESDVRWRIFQRMEQTARSIPDPRRRDYVLHLVAVAYADYDLLKMAYPIAISLGDSRDETLAHLIDVAIKQHDLAYAQAIIGYVQAPAAQIKHALNVTNALIEGAEFEAARHVLADIMPLAQAEHIVEINSLIALIEWRLGNQQQSQTLLDEAQTMSAHLNPDLRSDAWLAVIKSYVHQGDLLKAASLHRKIQSVQVWCDLIMFYRDRAEVTIATELAIAMTNAHFRDSACFALVEWYCTHAEFAAAQRLIELIGFDWDKVKAYCLLASSYAENLQFEQMLAVMQLAHHTVPREQQHSIPSLLVIADTYARHNLHEQARSVFEQILALFLSGQRYNRDEHNLHFVQSTQRYGYLDLSEPLIQRLFTLGDYGFNNDLVERIAKVYAEQGELAQATQIIQSIGQDYQFIQAAQGLVLSTTNQQSAASESLLLAARQRVAQINSDGPSALKTLCELADTALQLGLTAIAQTLLSDVHQSLLRKPHLLHHPLLQYEAWLLKSYQAQHKLADLIELARLIDDPQAHDRWIGAILEAYLQADDVGQAYQLLRLFNDFADVYAKSACKLAIKASQLGLNELATQVHPEALSACETVRESRYRIEYLRDLAVAQINYGDAGCLARLLQIFREQEAVFGQIDWYIEALCAIAVAFAEQGDAVAFADWLNYAHKRATAFPTGYQALAETYFGYTPDSAIKAFLDSIEQLVQISLDQGYADTALEALAKIYTSYAAHGHAEFLVKAHQTAISIPNRDYQYAALVTVAQAYLKIKVMPELQVIISELSQLGFDFWIFQDLTASCIEEGELHLAYQLILFDERHPVKDEVICNLIARLIQADQPIIAYQLTSEIYEADNRAGSLQQIIHYYLERQQITDVIKIIQTTWRDCQRSYELWQLSTIIVPLIPHYPWLGTAVLDSVPWLEQQLTRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD9</accession>
    <name>A9AWD9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-Nucleotidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2149"/>
    <dbReference type="EnsemblBacteria" id="ABX04789">
        <property type="protein sequence ID" value="ABX04789"/>
        <property type="gene ID" value="Haur_2149"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2149"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_5_2_0"/>
    <dbReference type="OMA" id="GDIHRIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2177-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005122099" evidence="1">
        <location>
            <begin position="30"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="227"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="532"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="722" mass="78450" checksum="9292A8BB0CBF953F" modified="2008-01-15" version="1">MDFAMWHNVKSKVGILLGFTLLVGSLGQAAPTKAAEKLCFNQPGVVECIAPEFRDYWEKNGGLPVFGYPQTAAYEEATPEGKFLVQYFERQRLEYHPEKPAPFTILLGRINDEVLLRENRVWRDFPTAPQATGCQLFSETGHSVCGEFLKYWNSQGLDLGENGITYGESLALWGLPLSDPQEEINIDGDKVLTQHFERARMEWHTKDGKNQILLTRLGVTLVPMQLKMLAINDFHGQISTGRKVSNKDVGGAAYLSSYIKQARAKARYSLTVQAGDMVGASPPSSALLQDQPTMEFLNMLGVNVGTIGNHEFDEGFDEMMRLIDGGCHPTAGCWEGANYPYVVANVIDKRTNKTILPAYHVMNIDGARIGFIGVVLENTPEIVIPSGVTNLEFIDEVTAINQAVTELNGQGVHAIIVLAHEGGTQNATTGAITGPIAEIANGINDDVDVIVSAHTHTSISGEVDGKLITQALSYSTAFADIDLTIDRAKRDIVAKKATIVTTFHEDMTPDADVAAMVKKYEDQVAPQVNRKVGTAASAITNTANAAGESALGNLIADAQRNTMSTQFAFMNPGGIRAPLDAGEITWGELYSIQPFSNDLVKMTVTGADIYTLLNQQWQNQSDGTVRARILQISGLSYTWTDANPVGQKVVEVLDGNGKALDKAASYTITVNSFLADGGDGFVVLKQGTNREVGPTDLDGFVRYIEKLAQPISANIENRIVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWK3</accession>
    <name>A9AWK3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4130"/>
    <dbReference type="EnsemblBacteria" id="ABX06762">
        <property type="protein sequence ID" value="ABX06762"/>
        <property type="gene ID" value="Haur_4130"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4130"/>
    <dbReference type="HOGENOM" id="CLU_1893324_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4176-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14851" checksum="48798462F90B4C77" modified="2008-01-15" version="1">MFWHIIKNARNPNRYQSNVYSNRRHNRRHHASFHQRHMHPSLHQHPSLQHHQQHHFDSDDLAAGIGIAAGMHVAQSWDSNNSGWDSSSSFDSGSWSNNDSGSSWSSGDSGGSWSSDSSSSSSSDSFSGDSSGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWQ6</accession>
    <name>A9AWQ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0659"/>
    <dbReference type="EnsemblBacteria" id="ABX03307">
        <property type="protein sequence ID" value="ABX03307"/>
        <property type="gene ID" value="Haur_0659"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0659"/>
    <dbReference type="HOGENOM" id="CLU_1861501_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-670-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17232" checksum="8C5130B214DA6D2E" modified="2008-01-15" version="1">MASLRTVAMALQRGVPPPWRAEVLQRVVLTVKSAIEQATPIKEGHLKANTRHEILSTGAKGRIYNRTPYAVFVHAGTKPHVILPKFTSREAARTIGGGAALLAFQIGGRWVRTRMVRHPGTRANPFMRRGLTDARPSLSLLLKLAAADLMSELRGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWT6</accession>
    <name>A9AWT6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0689"/>
    <dbReference type="EnsemblBacteria" id="ABX03337">
        <property type="protein sequence ID" value="ABX03337"/>
        <property type="gene ID" value="Haur_0689"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0689"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_1_3_0"/>
    <dbReference type="OMA" id="DKNHTNY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-701-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="5"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="2">
        <location>
            <begin position="332"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="449" mass="47504" checksum="14F1CEAAB9E718FF" modified="2008-01-15" version="1">MASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQALIARTPAQFARDGVTVKTEHEVIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNCPPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGAGYIGLEMAEALLDRGIGVTLVNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAELVIIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYLPLGTTANKQGRTLGAYLAGHERPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSKIIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDDVAKRVDVVAVALAGRMTVDEFAWQDLSYAPPFSSVWDPLLVAAQALAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW2</accession>
    <name>A9AWW2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0715"/>
    <dbReference type="EnsemblBacteria" id="ABX03363">
        <property type="protein sequence ID" value="ABX03363"/>
        <property type="gene ID" value="Haur_0715"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0715"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_0"/>
    <dbReference type="OMA" id="GFCETVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-727-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="28784" checksum="3D2C6BA37A2E2964" modified="2008-01-15" version="1">MTSQQKVVLITGASSGIGQATAELLAAHGFRVFGTSRNPISNKHSFTWLPLDVRSDDSVHAAVQSLLGQTGRLDILINNAGYVQFGAVEESSIADAQAQFDTNLFGVIRMIKAVMPIMRQQGSGRIINVSSIVGHIAPPYGGLYSASKFALEGLSESLSAEVRQFGVSVSLVEPSYVNTPIVTQPPTTLINDYTLGRQRAQQSLATNAKQGLEPGTVARVILQAATSKPRLRYPVGVDGTIALMLQRVLPEAVFEAFKRRLFSGDKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX03</accession>
    <name>A9AX03_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2171"/>
    <dbReference type="EnsemblBacteria" id="ABX04811">
        <property type="protein sequence ID" value="ABX04811"/>
        <property type="gene ID" value="Haur_2171"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2171"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="HVHRILQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2199-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23681" checksum="966C5DA9392C4BDD" modified="2008-01-15" version="1">MIKLLICDDQAVVRDGLSIMLNLAPDLEVIAVASNGREAVQLSATWQPDLILMDLKMPIMNGIEATRQISAAQPLVKILVLTTYDDDEWLFEAIRAGAAGYLLKDMAHSDLVSAIRGTVSGKAYVDPNVTARLLSQVATSRNQPPASQLTGRLTERELAVLNLIATGHTNASIAEQLRLSEGTVRNHVSTILSKLDVADRTQAALLAVEHGLHQRDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX33</accession>
    <name>A9AX33_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2201"/>
    <dbReference type="EnsemblBacteria" id="ABX04841">
        <property type="protein sequence ID" value="ABX04841"/>
        <property type="gene ID" value="Haur_2201"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2201"/>
    <dbReference type="eggNOG" id="COG3361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174010_0_0_0"/>
    <dbReference type="OMA" id="NIPYYWK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2229-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018644">
        <property type="entry name" value="DUF2071"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09844">
        <property type="entry name" value="DUF2071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="244" mass="28236" checksum="BD530AA0CD361E72" modified="2008-01-15" version="1">MPILHNPITMQGQIDRCWLLTYRMPIDQFQTLLPAELTATEYQGFGFWNIVICHVSHMRPWFAPHSLGFNYWHVAYRIYVNLKTPYGIDQGLYFVRSDCDQPLLAWAGNLVTNFNFHHTPVIVKSSVEQTSISINSSVAAASVQINNQQPAQLASDSIFDNLEQAAAYLKYPPRGIALSKPGEANIVRIERDEAAWQHQLRHVEQADVQWLKTYPVQPEICYEIQPIAYRWLRGYRRKVLLNQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX56</accession>
    <name>A9AX56_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2224"/>
    <dbReference type="EnsemblBacteria" id="ABX04864">
        <property type="protein sequence ID" value="ABX04864"/>
        <property type="gene ID" value="Haur_2224"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2224"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_228576_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2252-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735075" evidence="1">
        <location>
            <begin position="33"/>
            <end position="2494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2494" mass="275242" checksum="95C98EC324338D16" modified="2008-01-15" version="1">MSVNRPYRRLIHVGMLLSMLWSLFPASQPATAQTDQSNKTVEQAFAPDTGLTRDPQTPRLATALPKKASSRADFMPVAAQNLSIQPQLNQVVTAQLDSAKTTAVQFEQAPLSLLVEADTFATATRLEFQAQALPNLTQQLQRSSKSEGYLRDQAEQVTFYRFNIEAQTNDQAANFKKPVRMVLDLRQLMRDVPSNYQQFYLAYQDQADPNHWIEVPITLHDAKGLISADVDHFSTWAAGTRPERWNPSWVPAAVASFSGAATYAYPIEGPMGRGGLQPKVELSYNSRSLDGRIRDDTGAGPLGDAWSISDISIARVGVKTEFVAGFPSNKHPDNFRLTINGAGHELFPEFPSQTATASSMRYFAKDAPGYYIKRVYNTATPNTDGIYWIVVTPTGVTYRLGYYPHAEEHQIWDIGYWNVQGHQGRPNNERSALAWHVDTVTDRAGNQMTYQYVNWTVTEPIEWYLQGSSHKSTLQLTTWKSRIGSISYNYPNRVTALPVSDTVAQLSTTPASRLVFTTKTQFAYLIDTIYVYHGSLSTPIKEYRINLSGHFVDSPACMNQDTQPNIPRSTHTRVVNAITVASGVDADPTTEDGWTLPATSFTYEAKPHYNNNCFSFYYLKSMRSNYGGEISFNYASDNRWIGDYTYLGYDRYVWPSLGQSYYVVETLANDGRNPAVKTTYSYSQPCYGQWSSNVPAGAITCGASDAPEFGTITGFATVNQRSYDFNGTTLLKRNETIFSQNSATTSGKPMIQRNFAGDGTLLDATHSTYNTDSLHGLPNMFTYLSEVKSYQYSNGLEISTKRTFGYDVAKQAGVQYGNLTDTWLYASAAATTPYEKQVTYYTPNNGRATGGQAWMVNAPTASGRYDQQGTFLNGTWIYYDGATTNATAPTQGLVTRSRQTRPITCAEIPNPSGLPQPADPNCVHAFQTIDSDMTYDSFGNPKTTTIYSGFGYRSLKANFSDSLDWKPTETGQPNLSQVASLWYDSDYNLYPVKTTNALNQATTYEIYGFRNDAGNIAAVDGFQIQTGLLKSVTNPDATIVRYEYDPFGRLVNTFDSYSFTGFGDSTKWNGNPVIRYRYWDNYWNDSAVFANPAANQPFLISDEKRPGSYANPSSTGNFAYNDQTMYDGFGRAIQSRHIWADVDGEAKRQEIYSTTAYNALGQTICQTAPFNLPFYIDRGLVWPASPFVTTPCSDSSMAKTLTSYDNFGRVKQTTAADGSLNKANWSLVNNITVAGQNLFWQHQQINPKNQLEMRLINNQEQLVLRREYRGTADSPIVYSDTQFQYDTLGNINKISRRQPSNAGNGALIAPEATMVYNGFGHKLQINDPDMGTIKYRYNANARIIEQRTLNDSLLTNDDDVVCFYFDALQRNTSKNTTNAGANCSNTPILNGALWLANSSYYSSGAGKIGKLQSVKWNRDGNGAVDGESFNYNSLGLLTSHTRTLNGVSFSMQFGDFDALNRATTITYPDGEVATITHDLEGENSLSLGSHGALVSNIEYNARGHISLIDRTNGGHNTVFNYYGATGTANTGNSNFRLASINHQHSLLPSYTYEYDQIGNISLLYESGSLSGNTYFNYDELDRLTSTSGIYSHIYAYDKLGNLTNNNGIAQTYNGIGTQPHALRSTSQGNFFEYDQAGNMIVRNDASGLYQQAFDVEQRLYEVIDQHDQTTRFRYDPSGQRTTTFAADGTVTYDPFPNYQRTTVSSSNSAVDSLNAGVLCSDYNPETKSYGGAGYIMYSEIPVKQRFGNLPAANISDHFICVRNNTGVWEYDNDAGFYAFTPIASDLLVASFNYNATTVSPYLNQSGAIYGLRYGYTTSNLAFSKDVFGGTNNPGEFEIAGTHFKTNAFAQSVANHGYGVACQEDATGTGYLMYSAESVHSRFAEQAPDINNAAHFICVRHNGQTWQYDNNSAYFAFTPRQSDRLIGAIDFSNDSYTSYVGQTGTILGMQKGLSSSNLTITVNQWNGESNPGEFGIAGLNFTPQAYEVTITSAGMGINCLDTATGTGYIMHSRQALNQRFSQSIPAQLASKHFVCVRYNSTLSTWQYDDGSNYYGFTPRASDTLVASVNFSTDQVTSLAGASDSEFGITKGFVSGISIVANQWGGNSNAGEFQVIGNNLTTHTIDIGSKTVAIAGTPIATRRKHSVATSLVDQSLVFVYVDKLGSANTLMDQTGTAILNNVRYLPFGEERLGLNSAYSDRGFTGHQENRELGLTYMNARFYLPSTGRFISADSMIPEPSNPQSFNRYSYVYNNPINATDPSGHLPGDDEPEIPNPFPESNPIPNMEYSAYRKWLNFWQAYTDNDNPYIMIKQGDQLVESSVAIKAGSVSLSPDSVSVAGNWGLVGAEVSMPGAYKKGEGDNFLETLWEGTSAKILIGPQIDLIVVEVMPLALGIDPFTGNITLETSAGIGLVEGSTTINPFAKTDAIYVLQISDELHDKLMGRDPCALSVSFQDQQAAWTELINVVNSYGFNGTDPRWTLHSIPNYVYNGEENTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXG6</accession>
    <name>A9AXG6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4254"/>
    <dbReference type="EnsemblBacteria" id="ABX06886">
        <property type="protein sequence ID" value="ABX06886"/>
        <property type="gene ID" value="Haur_4254"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4254"/>
    <dbReference type="eggNOG" id="ENOG503465C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1693099_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4301-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="18246" checksum="E589BD07EA43E275" modified="2008-01-15" version="1">MNQKPEGCLWCEYRGPVLAGEIITVVNPQVTLQHELRRCPTCREAMVDIRWPDRIVRRKVRESPRRFRRSLWVVVYPVECAWCGSHNTDAYEVNATVSNPVSTRFKYDIYRCLDCQRPNAISYLGEVYVHRADQDKEFFSLWHLDPELEQSEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI7</accession>
    <name>A9AXI7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatB homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0753</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TatB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0753"/>
    <dbReference type="EnsemblBacteria" id="ABX03401">
        <property type="protein sequence ID" value="ABX03401"/>
        <property type="gene ID" value="Haur_0753"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0753"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1684158_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-765-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00237">
        <property type="entry name" value="TatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018448">
        <property type="entry name" value="TatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01410">
        <property type="entry name" value="tatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="156" mass="17460" checksum="A61EC9ECD66F525E" modified="2008-01-15" version="1">MTIFGIGPFEFVIILVIALVVVGPERLPEMLFQIGQWISKGRKMISDLRNQARNELGDDYESVEKMARQIRELDPRRQIQELGRSILSDDDRAMIVDLGLDPKTTAAANVIDPTPKPPAARPEIARQARMMLDDDLLDQPLDQALRAPAAEEQTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP3</accession>
    <name>A9AXP3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA hydrolase/transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0809"/>
    <dbReference type="EnsemblBacteria" id="ABX03457">
        <property type="protein sequence ID" value="ABX03457"/>
        <property type="gene ID" value="Haur_0809"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0809"/>
    <dbReference type="eggNOG" id="COG0427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030703_1_1_0"/>
    <dbReference type="OMA" id="FFMGANV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-822-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="264"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="428" mass="46552" checksum="B5681160FF51B65F" modified="2008-01-15" version="1">MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTDPKYRESFHTRALFIGSNIRSAVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQHGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHIHINRINFAVEVDEPIYEHAPAVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLVERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTAINSAIEVDLTGQVCADSIGTFQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIVPVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKALIDIAHPDHREALERAALERFHGEASLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXP7</accession>
    <name>A9AXP7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0813"/>
    <dbReference type="EnsemblBacteria" id="ABX03461">
        <property type="protein sequence ID" value="ABX03461"/>
        <property type="gene ID" value="Haur_0813"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0813"/>
    <dbReference type="eggNOG" id="COG2514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059557_0_0_0"/>
    <dbReference type="OMA" id="GGYHHHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-826-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="17"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="177"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="32200" checksum="F3C2E1E72F0E8028" modified="2008-01-15" version="1">MATFRTITPQSIDAATTLGVTTLRVADAGRSLVFYRDLLGFQVLEQTESTILLGSPNQVVLRLDVEAGLKRHPSHTTGLYHAAILLPTRLDLAYVLQRLLAVRYRFGASDHAVSEALYLDDPDGNGLEIYRDRPRNEWRWGANGEVHMVTESLDLYGVLAEITPTAPAWAGIPAGTKIGHMHLQVGNLRQAEEFYHGVLGFDIVAHYPGALFVSAGGYHHHLGLNVWQSQNGPQQPNDAAGLGYFEIIMPNQAALEIVRQRLQVAEVAVQEQVDGLVVHDPWQTELRFIVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR2</accession>
    <name>A9AXR2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0828"/>
    <dbReference type="EnsemblBacteria" id="ABX03476">
        <property type="protein sequence ID" value="ABX03476"/>
        <property type="gene ID" value="Haur_0828"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0828"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_6_2_0"/>
    <dbReference type="OMA" id="DGRCYWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-842-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="40069" checksum="9B1D86D3296823D0" modified="2008-01-15" version="1">MPPKPITIDCLIVGGGIAGCACAVHLARHGWQVLVLERPPVRPQRFGESLAPAARPLVHELGLDLDREHSICPGNLAAWGSDAIYHHDFLATPYGHGWHLNRPHFEQQLRQRCLELGVTFSSVSIGYLERQPERWIIGVGEQLFQTRWLIESTGRARWLARRLGAQTQIDGPKQLGLVAMLEPQAQPWPDQRSLVEAVADGWWYVARVPQSQMATIFIGQPTAAQRQKLALAEGWWQALKRSTWAKQWLDQHQLCAQPYWVDASSSRLDRCYGNGWLAIGDAAMSYDPLAAHGITVGLTSARDAAQSLIAANQGSVAALHGYGHQLEQAWQAYRQLRQQIYAQEQRWPNRPFWQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR5</accession>
    <name>A9AXR5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD_binding_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0831"/>
    <dbReference type="EnsemblBacteria" id="ABX03479">
        <property type="protein sequence ID" value="ABX03479"/>
        <property type="gene ID" value="Haur_0831"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0831"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-845-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="452" mass="50300" checksum="9F9745EDE2D551D1" modified="2008-01-15" version="1">MRRDHAIVIGSSIGGLLSARVLSEVYTKVTILERDTLPDGVQFRAGVPQGRQLHLLLMRGLLELEKLFPKLREDMKALGGNELDLMNDCRYLFAAGWAEPRPSDYRSIIATRPLFDAAILGRIRQIPNIEIQTRQEVTDLLFHGRQVVGVKLRNRDTGEQHELNANLVVDAAGRPSKLPEWLEQHQFGRVKETIYKSDVGYATRMYTAPADWQGWPAIFVMPMPPHIRHGATFLKVENDQWLLTIGGVGSQRPPTDSAEFEAWLARMRTPLIAEITQKFTPASQVYGYAKTENRWVHYERLPVMPAGLIAIADSVCALNPIYGQGITNTAMSVQVLAKHLQREGIGSAPWALIFQKALARRNKSGWLTTISEDSRLADTPTYRPILPIRVLQWYSDKVNLAAAGNRAATNAMVGAIHMIGSAASLFTPNVLIAASRFFRSQPPSSVPAAPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXW2</accession>
    <name>A9AXW2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2288"/>
    <dbReference type="EnsemblBacteria" id="ABX04928">
        <property type="protein sequence ID" value="ABX04928"/>
        <property type="gene ID" value="Haur_2288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2288"/>
    <dbReference type="eggNOG" id="COG3039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100560_0_0_0"/>
    <dbReference type="OMA" id="IAVIHPR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2316-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="90"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="22608" checksum="BFEE6703D830363C" modified="2008-01-15" version="1">MPTDDSIIRVFCIVDDRLAAVKKHPLANLHPSEVVTIGLLLALKGRSYRAFYRWLSANYRHLFPALPEQSRLYRVLVKAHGYTDQFLADPTILGIIDSIGIAVIHPRREGRSSAPLGKKGISNHRWIVGIKLAWLINQRGEVVEWSWLPANVSDQEFRDVVAWRAGQTIALGDRGFRVRADEDDGVPIKICGQGDWNCRF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY55</accession>
    <name>RLMN_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="1">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmN</name>
        <name type="ordered locus">Haur_4305</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AY55"/>
    <dbReference type="SMR" id="A9AY55"/>
    <dbReference type="STRING" id="316274.Haur_4305"/>
    <dbReference type="EnsemblBacteria" id="ABX06937">
        <property type="protein sequence ID" value="ABX06937"/>
        <property type="gene ID" value="Haur_4305"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4305"/>
    <dbReference type="eggNOG" id="COG0820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_0_2_0"/>
    <dbReference type="OMA" id="QVGCSLD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000350214" description="Probable dual-specificity RNA methyltransferase RlmN">
        <location>
            <begin position="1"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="97"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="1">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="228"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="(transient)" evidence="1">
        <location>
            <begin position="104"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="363" mass="40215" checksum="70628843D7514602" modified="2008-01-15" version="1">MNIYDLDLKGLTAQLTELGQPAFRARQIYAHLYKKLANDFAAMTDLPAALREQLTANLQIGSLELVREQTTDDGLTRKVLWRCPGDAVIETVLMIYPPDRATICVSTQAGCAMGCVFCATGKLGLLRNISSGEIMEQVLYFERYLRNEGAAIAKRHGGPVPDHITNLVFMGMGEPFANYERWWAAVERLNDKQGFNLGARNMTVSTVGLVKGIRQLADEALQVNLAVSLHAPNDQLRSELMPVNDRFDISDLMDAIRYYTDKTHRRVSFEYVLLDDKNDTPELAAQLASLVKGMLCHVNLIPWNPIPGTPLTRSHRERVTAFQRVVQAAGISCTVRVERGVEIAAACGQLAAIPSPTSPINLY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY92</accession>
    <name>SYS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA synthetase</fullName>
            <shortName evidence="1">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serS</name>
        <name type="ordered locus">Haur_4342</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AY92"/>
    <dbReference type="SMR" id="A9AY92"/>
    <dbReference type="STRING" id="316274.Haur_4342"/>
    <dbReference type="EnsemblBacteria" id="ABX06974">
        <property type="protein sequence ID" value="ABX06974"/>
        <property type="gene ID" value="Haur_4342"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4342"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_1_1_0"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000098078" description="Serine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="347"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <sequence length="422" mass="47436" checksum="ABA491AC33BFF3B8" modified="2008-01-15" version="1">MLDIRLFREQPELVREGFAKVGRDPGLVDQVIGLDLKRREAITEVERLKAERNAGSKDVARTKDKAERDVKIAAMKLVGDQITELDAQANAIDLELHNLLLDLPNLPLPEVPVGKDEHDNVVVRVEGTIQEPDFAVKPHWELGEALGILDFERGVRMSGTRFFVMKGLGVRLQRALISWMIDMHVDQHGYTELAVPYLVKADAMVGTGNLPKFADTIFHIEDTDLWLIPTAEVPVTNLHREEILDKAQLPLRYVAHTPCFRNEQMSAGRDVRGIKRLYQFDKVEMVKMVEPATSYDELFSLISNAEDVCKGLKIPYRLLQLCTADLGIATVKYDLEMWAPGMNEWLEVSSCGLFGDYQARRANIRYRPEAGAKPEFVHTLNGSGLALPRVIIAILENYQNADGSVTVPEVLRPYMGGIERIG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC1</accession>
    <name>PLSX_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plsX</name>
        <name type="ordered locus">Haur_0855</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PlsX family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYC1"/>
    <dbReference type="SMR" id="A9AYC1"/>
    <dbReference type="STRING" id="316274.Haur_0855"/>
    <dbReference type="EnsemblBacteria" id="ABX03503">
        <property type="protein sequence ID" value="ABX03503"/>
        <property type="gene ID" value="Haur_0855"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0855"/>
    <dbReference type="eggNOG" id="COG0416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039379_1_1_0"/>
    <dbReference type="OMA" id="HGKSNAR"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000089915" description="Phosphate acyltransferase">
        <location>
            <begin position="1"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <sequence length="368" mass="38849" checksum="C4F6B9CB2FAE46A1" modified="2008-01-15" version="1">MRIVLDASGGDHAPQATVAGAIAAARTWGDQIILVGDEASIRAELAKHDTSNLDLPVVNAPEMIEMTEHPAQAIRRKRNSSVAIGLRLVRDGEADAFVSAGHSGATMAGALFILGRIRGIERPCLVTHFPTVHGHALLLDSGATTDCKPEYLVQFAQMGNVYAQKIVNIAMPRIGLLANGEEANKGDKLVQDTHVLLQQRSDLTFIGNVEPKDMLINGSADVVVADGFVGNLVLKFGEGVFKMITTAASNNIKAEWRKNLVLGLLPALVALTLPGKGRWRALIAGLTGLTLPASMAVAPLLALRKRMDYRSHGGAPLLGVNGIAIVAHGKSDALAIQNAIGQARNAVEQRVVATISHALETVELVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH6</accession>
    <name>A9AYH6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional activator domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0910"/>
    <dbReference type="EnsemblBacteria" id="ABX03558">
        <property type="protein sequence ID" value="ABX03558"/>
        <property type="gene ID" value="Haur_0910"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0910"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_0_0_0"/>
    <dbReference type="OMA" id="HRYYIRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-924-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="853"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="3">
        <location>
            <begin position="938"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1064" mass="120533" checksum="DD69ADF73E13A22A" modified="2008-01-15" version="1">MCCATNKFYAKLRVVQYAIDYPQLNDDLIQRPRLQAQLEACWSCRLTMVVAAAGYGKTTALAQWMQQTLGGDWLWYGLHSPTEADQLQRLLSSLTKARFPQINPINSLADLFDCWATLAPRRIALVFDDCQHLQASAWRLLNELARFAPTNLHLILSSRQLPQLDWAGLAARGQYRQLTAAELRFSQAELQELLPTQSPSQRQAAWQATNGWPAGLRLWRALPSGYQGTVSDFLAQDVLGQLPEAVRRTAQFAALLPFFNQAVLTAMAAPDPASLWHYNLFVLPDHAEWWRFEPFWLEVLRQQPLAEITQLLAQAATWFEQQGHLAAALDVWCRLGQWAQVAEQLKHHGLQLLAQHQPVLQWLQQLPATERQTAELLHLDGLALREHDPGLAAQTLAQAAQRYRAEQRYAEAFQVVGEQCLIYFWQGDEQALIAVARESFSLKSFVWYRQRRDLLKFPLLLFQIKRGRYIKALATAQSLAQSELPFFWRWVAACVVGGLYTILTLPNEGIQWLEVWLQHPQVQAEPAMRMSLLDLLATCLMSRAAPDDRIAAQDLADQASRLSERYGVRLTRLQTRGTKLGLALLEADRPTTERLIQQLLLPSDEPLPSIMRNRLLALRAFAWASLGEIKLAQHDATLSERGLIRDDALYGADPRMWLMLAQAWFCCGEYQRALAALERAKPLIEAAQSPILRLRAGLVQLASRWQLQPSPQLIAEATTIWRDYLSDGDRHMNATPLHLTTLLVELGLRTGIAPQRIAQFLAERDRAALEEICWKLYAEQPQQQAALLQLLGLYGSAASLERLQEVIKQASTQQRKIAQHSLTSIRQRPAYALKIQLFGSLQLWRGTELVDPNEWSREKARQLLALLVLQRPRIISREALIEHFWPDLTPQAADGALRVTLNALLHVLEPERSGGANSAFVLSEAAGLRLNPQAQIDTDYAEFQTLLQTAAKQRQQGAMPAALQAYQAALALYQDDLLSDIAYAEWVLDWREQALSQFVAATSDYLELLLAYGPTAEAIPYAERLLSYDPYHEPTYLRLIDIYHMLGNASAAERIRKRLERISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ73</accession>
    <name>A9AZ73_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0971"/>
    <dbReference type="EnsemblBacteria" id="ABX03619">
        <property type="protein sequence ID" value="ABX03619"/>
        <property type="gene ID" value="Haur_0971"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0971"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_0"/>
    <dbReference type="OMA" id="FPTKGAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-985-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="30504" checksum="E033A11BD2ABB22A" modified="2008-01-15" version="1">MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGEVFTVPCDVRDPEAVDQMIEAVWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLHGTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPSAAAKAGVLALTRSLAVEWARYGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAGYINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD8</accession>
    <name>A9AZD8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2442"/>
    <dbReference type="EnsemblBacteria" id="ABX05082">
        <property type="protein sequence ID" value="ABX05082"/>
        <property type="gene ID" value="Haur_2442"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2442"/>
    <dbReference type="eggNOG" id="COG4732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100509_0_1_0"/>
    <dbReference type="OMA" id="PSFIMAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2470-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012652">
        <property type="entry name" value="ThiW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09512">
        <property type="entry name" value="ThiW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024534">
        <property type="entry name" value="ThiW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02359">
        <property type="entry name" value="thiW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="17771" checksum="4F8B3ED2C609DCA8" modified="2008-01-15" version="1">MTSLMQKQRQSTRRLAYSIVLAALGLALSPISISTGIAKISPTQHLINVLAAVLVGPWWGLAIAFVMALVRNLLGTGTPLAFPGSMIGVLLAGLLYQRWRNDWLAVLGEVIGTGLIGATVAALLVAPLAMGKSPALIAMLTPFAISALVGALLALASLGLLRKARLLPADE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE7</accession>
    <name>URE2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urease subunit beta</fullName>
            <ecNumber evidence="1">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Urea amidohydrolase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ureB</name>
        <name type="ordered locus">Haur_2453</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the urease beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZE7"/>
    <dbReference type="SMR" id="A9AZE7"/>
    <dbReference type="STRING" id="316274.Haur_2453"/>
    <dbReference type="EnsemblBacteria" id="ABX05091">
        <property type="protein sequence ID" value="ABX05091"/>
        <property type="gene ID" value="Haur_2453"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2453"/>
    <dbReference type="eggNOG" id="COG0832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129707_2_1_0"/>
    <dbReference type="OMA" id="FYEVNDA"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035550">
        <property type="term" value="C:urease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00407">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01954">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002019">
        <property type="entry name" value="Urease_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036461">
        <property type="entry name" value="Urease_betasu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00699">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51278">
        <property type="entry name" value="SSF51278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00192">
        <property type="entry name" value="urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000188924" description="Urease subunit beta">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01954"/>
        </source>
    </evidence>
    <sequence length="130" mass="14169" checksum="B598C45AF6ADA193" modified="2008-01-15" version="1">MQPGEYLIDQPTEAIAANLGRATCELLVAHTGDRPIQVGSHYHFFEVNRALVFDRGLAYGMHLNIPAGTAVRFEPGDSKIINLVAFAGTRQIYGHNGLVNGALDAVDQRQTSLNAVQQQQFGHRAQGDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ8</accession>
    <name>A9AZJ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2504</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2504"/>
    <dbReference type="EnsemblBacteria" id="ABX05142">
        <property type="protein sequence ID" value="ABX05142"/>
        <property type="gene ID" value="Haur_2504"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2504"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027555_0_0_0"/>
    <dbReference type="OMA" id="FDLCAQR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2532-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07129">
        <property type="entry name" value="ALDH_KGSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044151">
        <property type="entry name" value="ALDH_KGSADH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="18"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="55121" checksum="F434F0D8C34F7005" modified="2008-01-15" version="1">MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSSPEQRAKFLEGYADLIEAKRQELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNHTWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIAGSDFASAIAAGNAVIAKGHPSHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGLTLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLILEHSAASADFIEATKAHFNQHPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGYRYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAEVLRVLDCLEGNLTGSIYSSSNGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATIRRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ7</accession>
    <name>A9AZQ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4479"/>
    <dbReference type="EnsemblBacteria" id="ABX07111">
        <property type="protein sequence ID" value="ABX07111"/>
        <property type="gene ID" value="Haur_4479"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4479"/>
    <dbReference type="HOGENOM" id="CLU_2825225_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4534-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="66" mass="7695" checksum="A9473949BDCCBC4E" modified="2008-01-15" version="1">MLDLSLEQISYIKLRKRFIWFGKQGFEINYRQHPNAALLGFFFVSKQFQAWLDAFSAAGIKIIPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS1</accession>
    <name>A9AZS1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4493"/>
    <dbReference type="EnsemblBacteria" id="ABX07125">
        <property type="protein sequence ID" value="ABX07125"/>
        <property type="gene ID" value="Haur_4493"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4493"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_0"/>
    <dbReference type="OMA" id="CEGQALD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4548-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="37152" checksum="AB7B6677CEC15B4A" modified="2008-01-15" version="1">MKHISDESIRQAMQSAFPPADARVTMFYEMQEYHLGWRNAQLEPTQADSGKLLRPRFCLLACAAVGGDPQQAEPLAAAIQLLHDFSLIHDDIEDHSPTRRGRETVWKLWEVPQAINVGDGMFTLAQLSLFRLAEVGVESSVVVEIARRFNQTIIRLCEGQYLDMSFEQRLDISEGDYLAMISRKTAALIAAAAGLGAILGNANREQAAALYNWGEALGLAFQIEDDMLGIWGAEAVTGKPDAHDIWGRKKSLPIIHALAHADAEDGGKLAAIYQKEPLEASDIQIVLTILERTGSQGYTAGVAKFYHEQALAALADLQGEAEPIAELHALTKQLLGRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS2</accession>
    <name>A9AZS2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4494"/>
    <dbReference type="EnsemblBacteria" id="ABX07126">
        <property type="protein sequence ID" value="ABX07126"/>
        <property type="gene ID" value="Haur_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4494"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_2_0"/>
    <dbReference type="OMA" id="NHMIDAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4549-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="16333" checksum="05B984D553398013" modified="2008-01-15" version="1">MSLKMRFRFSPTQDGLVKVLGPLETEIMELLWKENQGTVKQIHRSLQHRRDIAYTTVMTTMSRLAEKGILHRTRDGLAYVYSPELSQDEFVQMVVQQVLDGLLDDYPDLTLNYVVDYLARNDPTQLKQLSRDAQNRYARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZW9</accession>
    <name>A9AZW9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1028"/>
    <dbReference type="EnsemblBacteria" id="ABX03676">
        <property type="protein sequence ID" value="ABX03676"/>
        <property type="gene ID" value="Haur_1028"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1028"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1076764_0_0_0"/>
    <dbReference type="OMA" id="IAWRVAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1045-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="29829" checksum="2F49A27627B664AE" modified="2008-01-15" version="1">MSWKSRVRPFIPKPVLQRYIAWRVANNQKTVRQRLFEQYGRYAEYTLTQRSLPELFPEGRQASIEVPVAAIVRDDTMEMPLAELLSLAGVTQISQPKTIFEFGTYMGATTRMMAQHSSPETKIYTLDLDVKTRNEYLRRNGYQFELSFTPGQHFHNTPEASKITQLWLGLEPFDFSPYYGQMDLVLVDADHSYPFVKADTEVALKLVRPGGVVVWDDYTWVDAHPECVGVTRCVNELAERLPIYRIKQTRLAIYRVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B002</accession>
    <name>A9B002_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ordered locus">Haur_1061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1061"/>
    <dbReference type="EnsemblBacteria" id="ABX03709">
        <property type="protein sequence ID" value="ABX03709"/>
        <property type="gene ID" value="Haur_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1061"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OMA" id="HLGWEIQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015594">
        <property type="term" value="F:ABC-type putrescine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03300">
        <property type="entry name" value="ABC_PotA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017879">
        <property type="entry name" value="PotA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="8"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="40190" checksum="486A1BB1C1DF8067" modified="2008-01-15" version="1">MNTPTWAVELDHVTKEFRGSVAVRDISLKIADGEFFSLLGPSGCGKTTLLRMIAGFENPSSGDIYIEGVLMGETPANRRDVNTVFQSYALFPHMSVAENVAFGLHMKNINKADIATRVKQALDMVQLGAFGDRRPKQLSGGQQQRVALARALINEPEVLLLDEPLAALDLKLRKEMQLELKSIQQRLGITFIFVTHDQEEALTMSDRIAVMELGKVLQVGQPTEIYERPKTRFVADFIGECNFIDGTVLAVENGAVTLETDGGVRVVGTGMFPVAAGDHAVLAVRPEKVRLVEGQQPQGTNVFAAIVERVAYIGSDTRIIVRLPDGSPFDVWEANTVSTLDPNQYYTAGDPVYVTWATQNSLILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B010</accession>
    <name>A9B010_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sugar fermentation stimulation protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sfsA</name>
        <name evidence="4" type="ordered locus">Haur_1069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SfsA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1069"/>
    <dbReference type="EnsemblBacteria" id="ABX03717">
        <property type="protein sequence ID" value="ABX03717"/>
        <property type="gene ID" value="Haur_1069"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1069"/>
    <dbReference type="eggNOG" id="COG1489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052299_1_0_0"/>
    <dbReference type="OMA" id="VTAHCPN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00095">
        <property type="entry name" value="SfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005224">
        <property type="entry name" value="SfsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040452">
        <property type="entry name" value="SfsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041465">
        <property type="entry name" value="SfsA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30545">
        <property type="entry name" value="PTHR30545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03749">
        <property type="entry name" value="SfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17746">
        <property type="entry name" value="SfsA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00230">
        <property type="entry name" value="sfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SfsA_N" evidence="3">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="SfsA" evidence="2">
        <location>
            <begin position="91"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="26825" checksum="3BFD04CF82F01030" modified="2008-01-15" version="1">METTIQIGLVGGAPLVQATFLERPNRFLVLAQLADGAIVQAHLADRGRLLTKLVPAAQLVLGHKPAEGRKTAYQVAGVYQANELVSLDTGLPNRLVEAALRAQALAPFAEYRHVEREVKLGASRFDFGLAPAPPTKAKRHGGECPWLVEVKSVGDAEHGLALFPDAPTVRGRRHLLELAELHEQGRRTAVIFIVQRGDAQRVAVNRHVDPAFAESLAAVAARGVEIYAYRCPLSLAGIRLAEQLPVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B077</accession>
    <name>A9B077_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sigA</name>
        <name evidence="9" type="ordered locus">Haur_2548</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2548"/>
    <dbReference type="EnsemblBacteria" id="ABX05186">
        <property type="protein sequence ID" value="ABX05186"/>
        <property type="gene ID" value="Haur_2548"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2548"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_3_0"/>
    <dbReference type="OMA" id="HHVQAMK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="232"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="321"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="177"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="43769" checksum="B33E52333B8BC3DE" modified="2008-01-15" version="1">MIDKLLELAAKNQNRIKREDILSVLPEPETNIEALESLYEQIEEAGIEVVDADEAPNVADLDLDLDLDSDHDLDGALPDLSDIALDDPVRMYLQEIGQVPLLTAAEEVDLAKKMEVAHAANDTLLQDDGMLEHSDRISLKRHIDTGRAARQHLIQANLRLVVSIAKKYTSYGLTMMDLVQEGNIGLMRAVEKFDYTKGHKFSTYATWWIRQAITRAIADQSRTIRLPVHMGEAISQVKRTSHKLQQTMQREPTPEEIAEAMGITASKVRRTLEASMHPLSLEMPVGQEGEGRMGDFIEDDRVSTPVDAAAMTMLREQIEEVLQKLPERERKIIQLRYGLKDGRYRTLEEVGLEFGITRERIRQIEAVALRKLRHPHLGKKLRGYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B078</accession>
    <name>A9B078_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF87 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2549"/>
    <dbReference type="EnsemblBacteria" id="ABX05187">
        <property type="protein sequence ID" value="ABX05187"/>
        <property type="gene ID" value="Haur_2549"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2549"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_513616_0_0_0"/>
    <dbReference type="OMA" id="MITRRIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2577-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="2">
        <location>
            <begin position="139"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="542" mass="60611" checksum="B39839D560E1D2EA" modified="2008-01-15" version="1">MAHATRIGLVTSGSLLEGLTARLDERYEIERLRVGQFMVVQGRQNRFFSMLTDVQLAATSLSILADPPDDEHPLLREILAGRNTYGTFKLTPQLMLPEDSLETPRPVKTIPAHFAPIYEASEDDFGLVFGAEGDGKFQMGTPLDMDVPVCIDLERFVERSNGVFGKSGTGKSFLTRLLLCGVIKHNAASNLIFDMHSEYGWSGTTEDKIQEVKGLAQLFPGQVYIYTLDPESSRRRGVKYDGDITIGLNEIRVDDILLLQDALNLNPTAAESAFICAQRFGDDWIQKLRELDTEQLKEFVESTGANMSSMSALSRKLAQLEQLKFVTRKSSQSSIRQIIDALLAGKNVVVEFGQYRSELAYMLVSNILTRLIYDEWVRRTETFLATKKSSDKPPQLMITIEEAHNFLTPSLAKQTIFGKIARELRKYSVTLLVVDQRPSSIDNEVMSQLGSRITALLNDDRDIDAVFMGVGGSKGLKTVLASLDSRQQAMMLGHAVPMPVVMRTRAYDKAFYEAMMQGNRRRPKPIPITDDDANDDLFGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A9</accession>
    <name>A9B0A9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2580"/>
    <dbReference type="EnsemblBacteria" id="ABX05218">
        <property type="protein sequence ID" value="ABX05218"/>
        <property type="gene ID" value="Haur_2580"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2580"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753927_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2608-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="41664" checksum="E6D2070052AB8FD8" modified="2008-01-15" version="1">MKQVCLLCERTSFDNNLYCQEVYCQAEKSPTILGYGKWLGDIEIVRPVVVLRSSVLYEASHQKERVFLKVAHVGSENTERLKREAEFLKTVRVSNERNTFLPNWRPPYANATVSAQTEAYGRAMLGEHLFYYYLSDFFAGESLRDALTKNPQMWVNHIGWLVMRLASSVALLQSKGVLHFGITPDSLLVHFEDNPSVPTVYLLDLGIASTPQNINNDWYSFMVPPAYTSPEIMQPHLQKPSYATDVYGLGLILYEMLVGVPAYPFKLKSDEEVYQAVLKNHRINMNRTADVRAIAELAVRMVDTQVANRPQNAAQVVQELLKLFGEVPTAKKSRWPSLNTILIIVISLLTVAFLITFFVTLNQLNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B5</accession>
    <name>A9B0B5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2586"/>
    <dbReference type="EnsemblBacteria" id="ABX05224">
        <property type="protein sequence ID" value="ABX05224"/>
        <property type="gene ID" value="Haur_2586"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2586"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_646854_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2614-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="424" mass="45442" checksum="FB18CC9E8ADBBB46" modified="2008-01-15" version="1">MSKDVVQIQYEQTAQVAQHFGRLKQTVEQLQTTIRNVSQSLVDGDWQGDASVAFAKELDGEIYPTFNRLITAFQTAQEVTLEVQKIFGQAEEEAAALFKGELFGNADGGSKGGGSWLDSVGGFFSSVGNGIKDFFVGAGKELKDMVVGVWNMVTSPIETAKGIWHAVTHPGEFWEAFKAPYVEAWENGRPWEAIGRGTMFIGSLLIGTKGADKVGKAAKISKAATVADAASDIARVSNPLQAASDIGMLAKGGGAETAMARYIANQSSHVGAGTALTDRVVLGAFKADPASGFLGYIGEANAHGGRYFSTTSDVWNKLKPIAEGGNNRIWPVNREFLQAQLESGISRIDIKGSSIDDILTKRPQSYSAMEVRFMQSQAYQYGYRQVGNSWIKTGDWRASTTGRVIGGSIGPGGEILQTSQSLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G2</accession>
    <name>A9B0G2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CHRD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4549"/>
    <dbReference type="EnsemblBacteria" id="ABX07180">
        <property type="protein sequence ID" value="ABX07180"/>
        <property type="gene ID" value="Haur_4549"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4549"/>
    <dbReference type="eggNOG" id="COG2335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331977_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4604-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07452">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00754">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50933">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734463" evidence="2">
        <location>
            <begin position="32"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="3">
        <location>
            <begin position="389"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="3">
        <location>
            <begin position="535"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="862" mass="88158" checksum="48420DCB072B88D0" modified="2008-01-15" version="1">MLNRFRTPRMFSFVTLLSLFSLVVGLNLAQAAPRTTQGGGGFTPGNLVVVRVGNGSGTLSNAATPVFLDEYTPNGDFVQAVAMPTALNGNNRRLTMSGSATSEGALSLSGDGQWLLLAGYDADVGTTSVASSNSATVNRVVAKVSLSSLIDTTNVITDAYSANNIRGATGNGDNLWATGTGNPGGVRFLNGMGTTTTLITPTNTRVVHTYGGNLYFSSSSATSRGIFQIGNGLPTSAGQTITPIASATSPYGFVFLDREPSVAGVDTLYVVDDTSTNLRKFSFDGTTWTLQGVWAEPSTGFHIAAQDNGANGVDLYLTRGTNSLSKLTDTAAYNQPINAAALNPIVPVGANTAFRGIIVVPSPVQATPTPTETATVTPSETPSPTAVPSCLRFMVSLEGSQEVPPSGSNATGGGTVDVDTVNNILSYNLSYQGLSGTETAAHIHGFAPRGANAGVLVGLSTGSPKVGIFNYSEAQEANILAGQAYVNIHTDSFPGGEIRGQIDGATINCPPPTATPTETTTPTATETPSATPIPSCLRFMVSLEGSQEVPPSGSTATGGGTVDVDTVNNILSYNLSYQGLSGTETAAHIHGFAPRGANAGVLIGLSTGSPKVGTFNYAENQEANILAGQTYVNIHTDSFPGGEIRGQIDGATINCPPPTATPTETVTPSATATATATATGTATPSLTPIVTPPPSCITMTVSGSGSQEVPPNNSNGMVMGMIEINTVANTINYNLSYHDLSSAETAAHIHGFAPRGSNAGVLFNLPLGASKVGSVSYAENQEANILAGQTYINIHSSNFPGGELRAQLDGATALCATPTPTATGTATNTPTNTATATVTNTPTNTATAVPPTFRIYLPLTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K0</accession>
    <name>A9B0K0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_4587</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4587"/>
    <dbReference type="EnsemblBacteria" id="ABX07218">
        <property type="protein sequence ID" value="ABX07218"/>
        <property type="gene ID" value="Haur_4587"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4587"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097262_0_1_0"/>
    <dbReference type="OMA" id="LTHFTCV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4642-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX07218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14442" checksum="7EA1AB1D4AFB4D1C" modified="2008-01-15" version="1">MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSALAAAWSAGETEFIALAVVADTPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRELLPGGFSPESLAHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L7</accession>
    <name>A9B0L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4604"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07235">
        <property type="protein sequence ID" value="ABX07235"/>
        <property type="gene ID" value="Haur_4604"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4604"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_6_0"/>
    <dbReference type="OMA" id="PIFYNAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4659-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="190"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="371" mass="41279" checksum="0BD80D482388553D" modified="2008-01-15" version="1">MQIAIDASRLAVGQRTGTESYTTELVRALAQTDRTNHYCLYVNQLPAALPPLGRNWRIKPIPAPRLWTHLRLGPTWQIDRPDVAFVPAHVLPSLPPRRSVVTIHDLGYEHHPESHPARQRLYLRYSTLWSARMASQIIAISEATKRDLLHYTGIAAEKISVIYHGVHERFYPHSSEQTKATAAKYGLHGEYLLFISTIQPRKNLVRLIEAYAQARQRCPDLPILALGGKTGWLTEQITQQAQQLGISEHVAFLGYVADDDLPALLSGATIYLLPSLYEGFGMTVLEAMSSGVPVITSNVSSLPEVAGDAALLVEPSQTATIAAAIVELWQNPQQRHDFAQRGLAWAKQWTWQRCAEQTLAVLTTVGHHGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N1</accession>
    <name>A9B0N1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4618"/>
    <dbReference type="EnsemblBacteria" id="ABX07249">
        <property type="protein sequence ID" value="ABX07249"/>
        <property type="gene ID" value="Haur_4618"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4618"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735080_0_0_0"/>
    <dbReference type="OMA" id="QWLYAYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4675-MON"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="250"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="370" mass="40576" checksum="840D8C877C872EA3" modified="2008-01-15" version="1">MRRIIWLTLVFGLCFWAFRTSQAVTPALTDTYGFASFWQTNGGELIFGQPITDPLEQDELVVQYFENARFEYDPQTDSVGLGLVGRERTEWRDFGPQPRLAAASLRPEGANYDLTGSFRTFWETNGGVAIFGLPISPAQFEARPTGRFKVQYFERALMIEHPLLAGTPEEIELAPLGQEVAAASGLVEGMSYEQPYLFEFDPVAPAPVQTAAPQPVAEPTQVPPTAAPAQPTSQPVPTATPKPANPNVGKRIEVDISKQWLYAYENGTVVFDAPVATGKDGFNTPTGSYEIYAKVPLQTMRGSLGGETWVVPNVPHAMYFNGSVALHGTYWHNLFGSGTRISHGCVNLPLDAAAWLYNWAGVGTTVQVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0P3</accession>
    <name>A9B0P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase M19 renal dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4630"/>
    <dbReference type="EnsemblBacteria" id="ABX07261">
        <property type="protein sequence ID" value="ABX07261"/>
        <property type="gene ID" value="Haur_4630"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4630"/>
    <dbReference type="eggNOG" id="COG2355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_1_0_0"/>
    <dbReference type="OMA" id="DATHLCD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4687-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="350" mass="38618" checksum="AA3477B589DCFA79" modified="2008-01-15" version="1">MILVDAHLDLAYNAINLGRDLTKTVELGRQRATEQTVEWIAEAGTLTTTLAEIGLHTPSIVCGTIFILPAEAQTTLDGVAYATPDEAHDQAWEQLNWYKQQCAAGFLHLIDNQPALQAIQARNQSVPGLVLLMEGADGLRTPDELIEWYAAGLRWLGPAWQATRYAGGTGAPGSLTKLGLELLELMQRLGVALDASHLAEESFWQALEHFQGPIAASHSNCRSLLVGASHQDRYLSDEMIKAIIERDGVIGIALYNRMLRADWDGSKNHVSLEHVVMQIEHICQLAGNTQHVALGSDLDGGFGVEMIPAEIDRWSDLLKIGQALAKRGWHENDIAKVLGQNWLRWFQRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T5</accession>
    <name>A9B0T5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03805">
        <property type="protein sequence ID" value="ABX03805"/>
        <property type="gene ID" value="Haur_1157"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1157"/>
    <dbReference type="HOGENOM" id="CLU_2584929_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1179-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="9436" checksum="7CD2D30A5E5D15E9" modified="2008-01-15" version="1">MKREILMQGVELAPIVERLKEEGTKRGLSQSANNEYGPVFINHHYDLRIERDPGDWGQYRLMLMHKLQPKSSFFGMFRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B3</accession>
    <name>A9B1B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4669"/>
    <dbReference type="EnsemblBacteria" id="ABX07300">
        <property type="protein sequence ID" value="ABX07300"/>
        <property type="gene ID" value="Haur_4669"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4669"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_4_1_0"/>
    <dbReference type="OMA" id="VIREYHT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4726-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="197" mass="21449" checksum="00A201AFC38746ED" modified="2008-01-15" version="1">MSRKDSAKELILNKAVQMASVAGLNGLTIGSLAEAVAMSKGGISAHFKSKTELQVAAVDRASELFQAAVIGQVLAEPAGIARLSKLCDSWFSYLQQGIFLGGCFFTNAVLELDDLDNSEVRAAVLRYYHNYLNFIEQCIAETVQLGQFRHDTPIAEVALQFHGIEIAALVWRAVRSHEAQFATARAAIDNLIATYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F5</accession>
    <name>A9B1F5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4711"/>
    <dbReference type="EnsemblBacteria" id="ABX07342">
        <property type="protein sequence ID" value="ABX07342"/>
        <property type="gene ID" value="Haur_4711"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4711"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_0"/>
    <dbReference type="OMA" id="CVAVDFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4768-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="37042" checksum="3AE58D958DFA276E" modified="2008-01-15" version="1">MSSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSNTLGLIVSDIRNPFFTAVSRAVEDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVIFSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNVSAGYTLAQHLINQGYRRIGAIFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIFTSNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATELVLQRVADPQRPTRKIILQGELIVRESSVEQRVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R0</accession>
    <name>A9B1R0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1297</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1297"/>
    <dbReference type="EnsemblBacteria" id="ABX03945">
        <property type="protein sequence ID" value="ABX03945"/>
        <property type="gene ID" value="Haur_1297"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1297"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_4_0"/>
    <dbReference type="OMA" id="SICRIHK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1319-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24471" checksum="2EF9C10F2DE0D1A8" modified="2008-01-15" version="1">MDRNVLFAHVSFTRDLSPTIIAALSSHANEQTVERGQIITLEGDPAVAMYLVYSGRIKVVRHSIEGREHILHVVEAYDHFNTVPMFREARCPATSEALVTSQLLAIPREHIRQVAQQHPELALAMLGEFANRLHNLVGLIENLALHTVNGRLARLLLQQAALAEQNPNLAPLTQAEMAAHIGSVREMVGRALKAFDAQGLIRLERGIIEIIDPQGLAAQAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y7</accession>
    <name>A9B1Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2791"/>
    <dbReference type="EnsemblBacteria" id="ABX05429">
        <property type="protein sequence ID" value="ABX05429"/>
        <property type="gene ID" value="Haur_2791"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2791"/>
    <dbReference type="eggNOG" id="COG0392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075280_0_0_0"/>
    <dbReference type="OMA" id="WFGECAA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2822-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="33183" checksum="1BA8037248987EDB" modified="2008-01-15" version="1">MLGLALFSDIGKVGDSLSTFNWLMLPAVLGFTIFNYVLRWLKWDYYLRKLGQGTNVSYGQSALLFTAGMVMAVTPGKVGEVLKSGLLKRLNGTPISRSAPIVLAERLTDGLAMLLLMATGLALYPPARPAFVVLVILSVLGLALFQNRRIALGFIAWLERGRLARFAKPLHSFYENSAELLSGRLLIVSTIISVVSWAGECVAMYYVLRGFGAEASGSLLLQSTFIFAASTLFGLVSFLPGGLGASEVSSTLLITTLVKLGEGAATAATIVIRFCTLWFGVLLGIVAMSIFAHRYGLIESEATNLAKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B248</accession>
    <name>A9B248_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4767</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4767"/>
    <dbReference type="EnsemblBacteria" id="ABX07398">
        <property type="protein sequence ID" value="ABX07398"/>
        <property type="gene ID" value="Haur_4767"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4767"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_348077_0_0_0"/>
    <dbReference type="OMA" id="HMSINRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4825-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="595"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="810" mass="89006" checksum="6495CDA22AF76AB6" modified="2008-01-15" version="1">MAQANKPKPTIAWSLIGGLALGPILLIILRLFPALDLRIQSPAGHFWIVTSALLVGLLMIGLVIRAALVRRDGRALMLGFGFLAMSLMFLIHAIATPGVMFENTSVATQWSTPLALLVAAIIFALSMSQRLAEGLIRWWGRWLALGSGLWLAYAGLMLVYIPTTVMPAIQAPTTQAGQVSQNGYDEYGDEYGYGDEADPTSVATTQPTQSSQSKYGDTYDYGYGDDESIAAPLGTPQPTSATNPHSLHSQMRSLAPTIFPFVVWLTVALFGWTAWFYGKQWRETPTLPLATFVIAAILLAETALAALYGELWQLSFWSYHVLLLAAIGTITYGVIRGVERTGSLTSAVEGLLLNSTLQRQQAGFQNAMSQLLNAFEAGDRTASQHLRRELSQRFALAEDQLDLLQHAVGLVEQDREQGRRLQALVDISHTVTLELEADALISRVIASLANMLQPALAAVGLLEAEQLQIQAQHYLIKGEPSHQSLSLPLSAFPMEWLTVTDLPYISALTGPLKPLAVNLQPAYLVPLQHHTQLIGILFLQLNADQAIDARSEGVLQSVAAHLATGITNSRLYSALQTEHQQLQRSEQLREQMNQMVVHDLKNPLTVIINYLDLLRRQALPESQRELVEGARRSSRTLVGLVSDLLDTARLQEGHMSINREHVPIAPLLHNVANELRSWAEQEAKIISIQADPELYATIDGDLMRRVLSNLLSNAIKHTPIQTEIKLIAYQADSQITFQVADNGPGIPEALQASLFDRFTILNEQNHTRQRSTGLGLYFCKLAVEAHEGEIGVVSNSTTGTIFTITMPHHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A1</accession>
    <name>A9B2A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase (GDP)</fullName>
            <ecNumber evidence="3">2.7.7.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.22" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4821"/>
    <dbReference type="EnsemblBacteria" id="ABX07451">
        <property type="protein sequence ID" value="ABX07451"/>
        <property type="gene ID" value="Haur_4821"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4821"/>
    <dbReference type="eggNOG" id="COG0836">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035527_0_1_0"/>
    <dbReference type="OMA" id="LIVCNEK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4880-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008928">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GDP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="2">
        <location>
            <begin position="315"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="39719" checksum="0AA4CA261512CFB2" modified="2008-01-15" version="1">MDILVLAGGTGSRLWPRSRRTKPKQFLPLLSNRTMLQETVDRVRPLIEEGRVFVVTGSDYEELIREQLNDVPRNNVILEPSGRGTASAIGLAAIHMRRSAPDAVMAVLSADHLILRNEAFRQALQAAEVAAREGYLVTLGVKPSFANTGYGYIQCGELITEAHNHKIHRVQRFAEKPDHDTAERYLAQGNYFWNAGIFVWQTKTFLDAIGRHMPELRNQLNQVQASFGKSRYHDTLAHVWENVENITVDYGIMERAPNVAVVPVDIGWSDVGDWHTLTTLMSDDDSANVVIGPHVEVDTKSTLIYSDSGRMIATIGLDGFLVVDTGDALLIAPRDRAQDVKKIVDQLRTEGRNDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E2</accession>
    <name>A9B2E2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1342"/>
    <dbReference type="EnsemblBacteria" id="ABX03987">
        <property type="protein sequence ID" value="ABX03987"/>
        <property type="gene ID" value="Haur_1342"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1342"/>
    <dbReference type="HOGENOM" id="CLU_487262_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1363-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="559" mass="60383" checksum="63994F2E1441F10F" modified="2008-01-15" version="1">MQYAISLYDPFTNVQLARFDRQVTDATLSTNGLTASVRLAPFIAKTLYAQARLLTAVVQRSDGKILRYRTVTLRLIDQGLALECHTLIVALDDLEYDGWWSVTTLDGWLPVETTSSTPERWEMRHDDGTISLSPRKNEQFSNAKGIGRQSLFIPANLNTTGFQVIQFDWRSKGPTNWLATFLAAERDYSSQTGATTIALGNGTAQTGSLCFTFAARPLVSVAMYYNAALATYIGETGDDYLKISNLRVATVTTNMVNTTTSGAIAIGTAFVPVASTLNIAVGQRLTIESGGVNSESVVVLAVTATQFQATFTKTHVIGSTVRGIVVTDKEIVEDVLSKALATNPTSGIKQSSARISKSSRDCLEAVWSAASGLSVVQELAAQAQYVTYVDDAQYLYYGPKEVGRTFALVDGSIELEKALGEATNQVRVGYKNASNQPLYTAFAEHASERYALGIVRQRTLASETTDATEAATLRSVALTDAAPTVRASLGVRAVRNDYNVREPLDTLTRGDVITIGDLSGAINKRSYTLAETSVNLVTGEVSVTPEAPIKQLDRWLAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J1</accession>
    <name>A9B2J1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04036">
        <property type="protein sequence ID" value="ABX04036"/>
        <property type="gene ID" value="Haur_1391"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1391"/>
    <dbReference type="eggNOG" id="ENOG5033SMW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_568339_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1412-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="343"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="480" mass="53236" checksum="FF71C985C7871C9A" modified="2008-01-15" version="1">MLDRIIPNILRRFKRPVATVPVSDGALLPTHPRRPCPLSMPDLPPIIAADPTAAAAHQWLAPIPWHALPPLSDRPRPGPRPAPRAPFLAAFLLKLDLQLPSMGHLRRYLLRHPALVWTLGFPLRPDPAAPLGFDVAASVPSRRQFARVLRTLPTPMLDFLRMALVRRIRDALPPDHHATFADTIAGDTKHILAWVKENNPNRFAPDRAKKQVQPPGDPDCRLGVKRRSNQQPTPTTDGQSPTQSKAEAYWGYASGIVVTRTPFGSIVLAEHTQPINAGDMTYFDPLMAQVEQTLGRRPRNGVWDAAFDSQRVYTYFHTAGGMAAVPVRKPNQPRQFSPDGVPLCAAGLAMPQQFTYAMNTNGPPQERARHRCPLLYPTATGEPCPTNDKHFATGGCVTTIGTQVGATLRWTIDRGSAAYKALYRERALVEQINSQAYALGIEWPKLRRQSAVTAWTSLIYVVINLRVVHRQQGTHDPIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M3</accession>
    <name>A9B2M3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative membrane-associated zinc metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_2836</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2836"/>
    <dbReference type="EnsemblBacteria" id="ABX05474">
        <property type="protein sequence ID" value="ABX05474"/>
        <property type="gene ID" value="Haur_2836"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2836"/>
    <dbReference type="eggNOG" id="COG0750">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025778_1_3_0"/>
    <dbReference type="OMA" id="QYMVGFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2867-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="12"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ_6" evidence="11">
        <location>
            <begin position="132"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="39358" checksum="3EE744A1A59E1414" modified="2008-01-15" version="1">MDFSSLAWLAVIPALGFLVVVHELGHYWVGRKMGIKIEEFGIGLPPRAKVLFVRKGIPFTLNWLPLGGFVRFAGEEGGFDDPDSLASASPRRRIPVMAAGVIANVITAIIMFAIIFAIWGYPNLDKVMVASTDEFAANAGFQVEDVFVSINGTAISTDEQVRLLVETSGGEPLDVIVQRAGAEQSLKVTPQYSEEAQRYRFGVGLGNPRESVNIFQAIINGFTYSFRLLGEMFMGFAMLIGGLLGTNAAPEGGLAGPVGIARLTGQVARSGLRDYLNFTALLSLNLALINILPIPALDGSRIIFALIEAIRRKKIPPEREAVVHAVGMMMLLGLMLLITVSDVRNIISGEPAITMPPTPTPIVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T2</accession>
    <name>A9B2T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05533">
        <property type="protein sequence ID" value="ABX05533"/>
        <property type="gene ID" value="Haur_2895"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2895"/>
    <dbReference type="HOGENOM" id="CLU_2034872_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2926-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732386" evidence="1">
        <location>
            <begin position="28"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="12499" checksum="574C602A19AD5C68" modified="2008-01-15" version="1">MFKISRRMLGLVAATCALALAPLTPTAAAPQAGPLTAGVSCYSLGIQYNRGAFACDAYVSGGTGSYSYNWSPVLNADIGQNGGDYVLGSCTLGRTARVNLVVTDSSGASVASVGRFYCSSDPS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B327</accession>
    <name>MOAC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="1">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">moaC</name>
        <name type="ordered locus">Haur_4860</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MoaC family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B327"/>
    <dbReference type="SMR" id="A9B327"/>
    <dbReference type="STRING" id="316274.Haur_4860"/>
    <dbReference type="EnsemblBacteria" id="ABX07490">
        <property type="protein sequence ID" value="ABX07490"/>
        <property type="gene ID" value="Haur_4860"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4860"/>
    <dbReference type="eggNOG" id="COG0315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074693_1_1_0"/>
    <dbReference type="OMA" id="IWDMVKS"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000139276" description="Cyclic pyranopterin monophosphate synthase">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <sequence length="164" mass="17518" checksum="5B324FBDC7820CDA" modified="2008-01-15" version="1">MLTHLDDQGRAHMVDVGDKAVTQRQAQAQADVRMQPATLDLLVAGELPKGDVLATARIAGIMAAKRTADLIPLCHPLPLSSVAIEIEAHPAQSLLRIISTVRCTGRTGVEMEALMAASVAALTIYDMAKAVDRAMVIEQVFVRNKTGGARGDFQHPLTPLDTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B353</accession>
    <name>A9B353_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4886"/>
    <dbReference type="EnsemblBacteria" id="ABX07516">
        <property type="protein sequence ID" value="ABX07516"/>
        <property type="gene ID" value="Haur_4886"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4886"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069129_5_0_0"/>
    <dbReference type="OMA" id="VGECFNY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4946-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="39"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="29111" checksum="CE89911C07507938" modified="2008-01-15" version="1">MYNDYATIYRQAGQSWLSLHMLNWLLPWLEQQAWHGSSVLDLGCGTGDAAVALALQGYQVTAIDRSEAMLAQAQLHGELQHAIVNWQQADLITWQAGAGYDLIISLFDTLNYVLEPTQLGALFQQIARSLNPQGWLVFDLNTPLLYATWPERNHVIVDRDDLYIYNVLDFDDEAQIGIGRIVWFQRQAEAWQRGSETHLQAAYSDQQIVELLADAGLSVVARLDRNGEQADLVQATRVVYLVQVSDVHNHSAAIPPILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B359</accession>
    <name>A9B359_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4892"/>
    <dbReference type="EnsemblBacteria" id="ABX07522">
        <property type="protein sequence ID" value="ABX07522"/>
        <property type="gene ID" value="Haur_4892"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4892"/>
    <dbReference type="HOGENOM" id="CLU_2000770_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4952-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13960" checksum="0F2C812D1A63F3DB" modified="2008-01-15" version="1">MYVVPHDQDSYQSINQPLLWLSGLNAGWSVWATQQQLAQIDLLWVGGLLAGYTGLLAWLRTLSFQRRRLVIDGLLIVLSIALGLVGTVVFVQITSISAAVWPWLRQMGLVVGLLLWQQWRMIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A8</accession>
    <name>A9B3A8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1427"/>
    <dbReference type="EnsemblBacteria" id="ABX04071">
        <property type="protein sequence ID" value="ABX04071"/>
        <property type="gene ID" value="Haur_1427"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1427"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_2_1_0"/>
    <dbReference type="OMA" id="DENHWIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1449-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="450"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="682" mass="76359" checksum="440E3ED88155D257" modified="2008-01-15" version="1">MAELRNWQATSLLELRFISDAQISPNGEQIAFVETWIEETTNKSGTRKPDYRSAIMLIQADGGIPQRMTFSVSGRDSSPRWSPDGSKLAFISTRDAGVAQLFVLDLARGGEAQQLTSLGYGVAEINWRPDSQALAFISRGAKAKAQTHVESLRDEKIIERLPFKFDGVGYLQPEYAQIWLVELGQEPNQITDQAFDHADPAWSPDGSELAFITVSRAELEHTRQADMYLLNVAAGTSRCLTNALGPVYHPTWSPDGSQIAYIGHDQHTGNASNEALWCVSRAGGDARLLSVGFEYGLENSVISDARIGRFPYRPYWRDNGIYCLATRAARTRAYRYSDGAMHELTPEDNPSISGYSQSLNKRTAFTAGTATQLEALYMGDADGSIHLLYDPNAALLTSIQTIEPERFTYNSFDGLEIEGWVIKPVGFSQGQQYPSLLYIHGGPHSAYGHNFMHEFQVLAAAGYGVIYTNPRGGTGYGQRFRALVRQDFGGDDYRDLMAAADLAETWDWIDSKRMGVLGGSYGGYMTNWIISHTERFAAANTQRCISNLMSFFGTSDIGPYFGEDEFGGKPWADIDKFMERSPIRYVNSINTPLLILHSDEDHRCPVEQAEQLYTALKVLDKPVRFVRFPREGHELSRSGEPLHRIARIEYILDWFGHYLQGHELKPADHFRRSVAGEWQSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q3</accession>
    <name>A9B3Q3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Terpene synthase</fullName>
            <ecNumber evidence="2">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2987"/>
    <dbReference type="EnsemblBacteria" id="ABX05625">
        <property type="protein sequence ID" value="ABX05625"/>
        <property type="gene ID" value="Haur_2987"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2987"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042538_4_2_0"/>
    <dbReference type="OMA" id="DLIEYAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3019-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="338" mass="38717" checksum="1BBE325AFC286952" modified="2008-01-15" version="1">MPTRTTLHHLATLMPRDLPVLYCPFPAAIHPDAVAIQASTQAWADSFGLLDDLETRLSFNQRGYGTLMARAYPNALTERMPTIADWSTSLFLLDDQLDRFGREHDAGAMATLLQRLMKVLKGSPAKRHDLPIVQAMGDVTSRLVQGSPEAWQHYFFDSLRKSFAAVQWEANNRAQGYIPTQKTYAMQRLYTSGTYLCLALIEFGNNDFLHPQVRLHPMVRRLCEYVNRVVFYSNDIISLRKELLAGDWQNLVYLVHTQHQLPIGEALNYVARLHNDTINQFTRERIMLDKLAPEICSPSLYRFVDGLATWMRANHDWSTMTSRYQTSTEESHGSQYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3W1</accession>
    <name>A9B3W1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3461</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3461"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="PL1">
        <property type="family name" value="Polysaccharide Lyase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06097">
        <property type="protein sequence ID" value="ABX06097"/>
        <property type="gene ID" value="Haur_3461"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3461"/>
    <dbReference type="eggNOG" id="COG3866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021894_0_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3498-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018366">
        <property type="entry name" value="CBM2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PTHR31683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00561">
        <property type="entry name" value="CBM2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735434" evidence="5">
        <location>
            <begin position="31"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="6">
        <location>
            <begin position="29"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="486" mass="50466" checksum="CA5DA912A9D858FA" modified="2008-01-15" version="1">MKLSIARRWVIATGLATALIGAIQSPITNAQTGLSCQVNYTLTNQWGSGFQADVVVRNTGTSVINGWTVAWSAASGQQIGQMWNATFTQSGSQVSAKNVDWNASIAAGGSQSFGFTATTTGSLAVPSSFTVNGVVCGGSVSPTATRTPAATATRTPIATATRTPAVTATRTPVATTTRTPIATATVVPTNPPVSNGLIGWATVAGSGLSTTTGGTGGSTVTAANFTELQNYAKSSSPMIIKFSGTMQGTLTVASNKTIIGSNGALIQGNVKISGAQNIILQNFAINGNSCSSYDNCRAGSDALGISNSHHIWADHLTITNGQDGNFDINNGSDFITVSWSKFGYTTNKEHRFSNLIGSSDDAASTDSGKLNVTFHHNWWFGGAMQRMPRTRFGKIHVFNNLYTTTGNDYCVSSGYQSKVLLENNAFIGVNTPHRLHDGDLKAVGNLYQNTSGDQISTGVAFTPPYSYSAEAASSLSSSVQAGAGAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-02-10" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B477</accession>
    <name>NUOA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit A</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoA</name>
        <name type="ordered locus">Haur_4980</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 3 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B477"/>
    <dbReference type="SMR" id="A9B477"/>
    <dbReference type="STRING" id="316274.Haur_4980"/>
    <dbReference type="EnsemblBacteria" id="ABX07610">
        <property type="protein sequence ID" value="ABX07610"/>
        <property type="gene ID" value="Haur_4980"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4980"/>
    <dbReference type="eggNOG" id="COG0838">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119549_1_1_0"/>
    <dbReference type="OMA" id="CGVDPVG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01394">
        <property type="entry name" value="NDH1_NuoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023043">
        <property type="entry name" value="NAD(P)H_OxRDtase_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000440">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038430">
        <property type="entry name" value="NDAH_ubi_oxred_su3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11058">
        <property type="entry name" value="PTHR11058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00507">
        <property type="entry name" value="Oxidored_q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_5000286513" description="NADH-quinone oxidoreductase subunit A">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01394"/>
        </source>
    </evidence>
    <sequence length="118" mass="13397" checksum="5B589362E5E9C3DB" modified="2008-01-15" version="1">MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQYYLYALAFVIFDIETVFLYPWAVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J1</accession>
    <name>A9B4J1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1512"/>
    <dbReference type="EnsemblBacteria" id="ABX04156">
        <property type="protein sequence ID" value="ABX04156"/>
        <property type="gene ID" value="Haur_1512"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1512"/>
    <dbReference type="eggNOG" id="COG0259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058669_0_0_0"/>
    <dbReference type="OMA" id="QRSPFTM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1534-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridox_oxase_2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="23837" checksum="1AFBBF1DD895999C" modified="2008-01-15" version="1">MNESVYKLLDFSQPVTFELLLQHAWQLIADAVHDRNDPMHTPVFGTNDEHGSDQRVVVLRGFDPTTRRLWFHSDLRSPKIAVLQRDPRVSWLLYHPTARLQLRLRGLAEVHINDTLVDTAWQNSAVLGRRCYCGIAPGQISAEPNHGLNQELLDRQPTLAESEVGRANFCVISSTISNLDWLQLQFTGNYRAQFAWADDGSYTSQWVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P0</accession>
    <name>A9B4P0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol kinase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1562"/>
    <dbReference type="EnsemblBacteria" id="ABX04205">
        <property type="protein sequence ID" value="ABX04205"/>
        <property type="gene ID" value="Haur_1562"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1562"/>
    <dbReference type="eggNOG" id="COG1597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045532_2_1_0"/>
    <dbReference type="OMA" id="VNDAYFM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1586-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="32357" checksum="2EAC04A36D5856E2" modified="2008-01-15" version="1">MKRVTVILNPNAGNAHQRRAIAQGITEWRSNQGWQVRLRETRKAGDATSFAREEAKRNDLIVAAGGDGTINEVMNGLVGTDTALGALPVGTGNVWVRELQQSLNPLHAARQLADGHVELVDVGQANERYFLLMAGVGLDAAITREVHSADKKRLGRLAYVIKSLPVLWRLRGTRTRISLDGQPLKGNALFVLISNSRLYGGVLNIAYRAAMRDGMLDVCTMMGDSALDAPKLLAGILFRGYGVIQGLEYVQAREIEIACSKPLPIQVDGDAIGTTPMTFRVVPQTLRVLLPRTTEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q8</accession>
    <name>A9B4Q8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1580"/>
    <dbReference type="EnsemblBacteria" id="ABX04223">
        <property type="protein sequence ID" value="ABX04223"/>
        <property type="gene ID" value="Haur_1580"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1580"/>
    <dbReference type="eggNOG" id="COG4430">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076645_1_1_0"/>
    <dbReference type="OMA" id="WIDGQAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1604-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="204" mass="22845" checksum="E013C264244F73FF" modified="2008-01-15" version="1">MNTSVFLTECVMSEQPKAELPTLSFVDQAAWREWLDAEHATSKGIWLKMAKKATGIASINYAEALDVALCYGWIDGQKKSFDEQAWLQKFTPRGKKSIWSNVNRGHIERLTAAGLMQSAGEAEVARAKADGRWDAAYDSQKNATIPEDFQAALDASPTAASFFATLKQAQRYSFLFRIQTAKKPETRSKRIQEFVSLLERGETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B554</accession>
    <name>A9B554_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3555"/>
    <dbReference type="EnsemblBacteria" id="ABX06191">
        <property type="protein sequence ID" value="ABX06191"/>
        <property type="gene ID" value="Haur_3555"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3555"/>
    <dbReference type="HOGENOM" id="CLU_1675508_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3592-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="18552" checksum="A842F8E2DE4EDED9" modified="2008-01-15" version="1">MVILINIASILLINNEFALAIVIGLTAALAFYLFYIQKQGYLNINAEYIEFQVYLKRMRIDWKCMRLVTVESYYYPQKLIPKAADYMKFKFIYNNGKISEDGISASIFTQADCVAIEQELYQYCRQYKIKMRKQLLKYSGRNQFSLQHDEFLVGRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E8</accession>
    <name>A9B5E8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ordered locus">Haur_0121</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0121"/>
    <dbReference type="EnsemblBacteria" id="ABX02773">
        <property type="protein sequence ID" value="ABX02773"/>
        <property type="gene ID" value="Haur_0121"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0121"/>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067287_1_1_0"/>
    <dbReference type="OMA" id="DGPFNGF"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="21779" checksum="45A0D69D96D56C12" modified="2008-01-15" version="1">MSDNEEEKSTTPEGVHWYVIHTYSGYENKVMQNLRHRIESMDMRNQIFRVVVPTEEEIEIKNGQRRTVQKKVFPGYVLVQMAMTDDSWYVVRNTPGVTSFVGMGTKPSPLADEEVRFILKQMEEEAPKVKVNYEIGQTVKITDGPFTDFEGVVDEIDEERGRVRVLVSFFGREAPVELDFLQVIRVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F7</accession>
    <name>A9B5F7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0130</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0130"/>
    <dbReference type="EnsemblBacteria" id="ABX02782">
        <property type="protein sequence ID" value="ABX02782"/>
        <property type="gene ID" value="Haur_0130"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0130"/>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083538_0_0_0"/>
    <dbReference type="OMA" id="CVITRRA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-133-MON"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022470">
        <property type="entry name" value="PTPS_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00987">
        <property type="entry name" value="PTPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX02782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="31945" checksum="6657395D566C6D4E" modified="2008-01-15" version="1">MDVFATRRFNFSASHRYWREEWSLEQNEAVFGKCTNRYGHGHNYELFVTVAGAVDPITGMVMNMVELKRLVTMVLDQFDHKHLNEDTPYFREVIPTTENLVRVLWGLIEPQLPKGVRLAKLRLYENSDLYAEYFGRQQQATFNRRYEFSAAHRLHAQSLTDEANREIYGKCNNPNGHGHNYQLEVTVDGLIDAQTGMVIDLVDMDRRVQSVLDNWDHRHLDYQVAEFAEQPSTAENIVVVLWQRLEALFGSQLKHLRLWETANNVFDYPLSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G1</accession>
    <name>A9B5G1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02786">
        <property type="protein sequence ID" value="ABX02786"/>
        <property type="gene ID" value="Haur_0134"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0134"/>
    <dbReference type="HOGENOM" id="CLU_2000764_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13541" checksum="C03C602FFA9CA6BA" modified="2008-01-15" version="1">MIFDLCLLPFRGIAMANSISDFFGSNNAGFGDVNIDAVIAGNNNQINKYLQLPTQTDPLPAALARLATLPLCDVRSRKKLLYGANTGWSLLFHQQYPTRYCGTVTSRGKPEDNVSTTDWSGQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I1</accession>
    <name>A9B5I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0154"/>
    <dbReference type="EnsemblBacteria" id="ABX02806">
        <property type="protein sequence ID" value="ABX02806"/>
        <property type="gene ID" value="Haur_0154"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0154"/>
    <dbReference type="eggNOG" id="COG0123">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_8_2_0"/>
    <dbReference type="OMA" id="CFWHSTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-157-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="19"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="37683" checksum="E95611C713874D5D" modified="2008-01-15" version="1">MSLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQRMAQFGDWADAETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWDVHHGNGTQDIFYQNPDVLYISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPELLIISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQSLTATLQTWVSGQPAPIFNQEVSHTPEPDVTWLIEHLRREHPLLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I6</accession>
    <name>A9B5I6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0159"/>
    <dbReference type="EnsemblBacteria" id="ABX02811">
        <property type="protein sequence ID" value="ABX02811"/>
        <property type="gene ID" value="Haur_0159"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0159"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_4_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-162-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="79" mass="8369" checksum="A578EB6D66F5F207" modified="2008-01-15" version="1">MIISIRLFAGLREALNQSSLNLDVAETATVGTALAQLAELHPKLPLTGLAYAINRQYVTLEATLQPNDELALIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5L5</accession>
    <name>A9B5L5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1605"/>
    <dbReference type="EnsemblBacteria" id="ABX04248">
        <property type="protein sequence ID" value="ABX04248"/>
        <property type="gene ID" value="Haur_1605"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1605"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_0_0"/>
    <dbReference type="OMA" id="MKSARMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1629-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735469" evidence="4">
        <location>
            <begin position="26"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="124"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="595" mass="63902" checksum="E6DE085A0A3CAEFA" modified="2008-01-15" version="1">MSFRKPGKRSIGWLLLLVLMIPLIAACGETAAPTATVGSTPATGGEPTAAPTTAPTDDTAAATPTDAAAATEEPTMGDADKYLVFGGSGEPDSLDSMDTTTGTALIVTRQIQESLLGFKAGTLEVVPELATKWEPNADATEWTFTLREGVKFSDGTDFNADAVVFNFQRLFVPDFEFGFRAEGKQYNIVPDIFGGYAGDPNSAFKEIMAVDPTTVKFVLTRPVPLLPSYLAASYFGISSPEAVKAAKEKYGSPEVGGVGTGPFKFERWDAGQSITLVRNEDYWGDKAKMPGVVVRFIAEAPQRLAELEAGTIDFTINLSADSRDKIASSADLQVVDLTPFNIAYLSLNMNNKPFDDVRVRQAVAYAINKQEILDASYGGVGSIADDFLPDGLAEYRATDLEPYAYDPEKAKALLAEAGYADGFSTMVLTDGTELPLELWYMPVSRPYYPDAKSVAELYAAQLSDVGIKVELKTEDWGVYLDNWDAGLKNGMVMLGWTGDYGDPNNFLFTHFGPGNADEAGYTNEKVWQLLADAGGASSPAESIRLFQEAGKLINTDLPRIPIVHAPPVLAAKKALQGWVPNPTGGESFAPISITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S0</accession>
    <name>A9B5S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1660"/>
    <dbReference type="EnsemblBacteria" id="ABX04303">
        <property type="protein sequence ID" value="ABX04303"/>
        <property type="gene ID" value="Haur_1660"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1660"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029469_2_1_0"/>
    <dbReference type="OMA" id="HITIPGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1684-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="196"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="457" mass="49323" checksum="48B44121AA0132CC" modified="2008-01-15" version="1">MTVDAALAWVNDRHDDLLARFSELLRIPSVSTDPAYAADVQRCADWLVGDLQRIGFANCQAIATSGHPVVYGEWLKAGSAAPTILVYAHYDVQPVEPLELWKNPPFEPVLRDGKLYARGSIDDKCGAFANLIAFEALLATTGTLPVNIKVIFEGEEETGSPSMEPFVREYQALLAADLMLICDGGSLPDQPLMFYTARGIIGAEVKVTGPSHDLHSGLVGGAVQNPIHVVGNIIAALHDETGRIQIPGFYADVQTPSATEQALMDAQEQDFFAMLKNESGRESFWANELGSLVARTTALPTCDVNGIWGGYQGAGTKTIIPAEAGFKVTMRLVANQDPQAVLESFCQFVQGFTSSTAEVHVTKGQTSYPVNLLYDGPVIDALQAAFEATWGKPAMLYRQGGSVPIMGMFQRELGIDLATLGFGTGDNGHAPNEYLLVDAFFRGVATAIHFYTRMGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y7</accession>
    <name>A9B5Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3143"/>
    <dbReference type="EnsemblBacteria" id="ABX05780">
        <property type="protein sequence ID" value="ABX05780"/>
        <property type="gene ID" value="Haur_3143"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3143"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_5_0"/>
    <dbReference type="OMA" id="MAWFFTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3175-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="37"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="24584" checksum="A0A5C611B98465C4" modified="2008-01-15" version="1">MSRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHVYFMTKAEMFDGGFMDWVITRAGAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTTRTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWFGRPTVTITIGEPQTLEQLAQSNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z4</accession>
    <name>A9B5Z4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05787">
        <property type="protein sequence ID" value="ABX05787"/>
        <property type="gene ID" value="Haur_3150"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3150"/>
    <dbReference type="HOGENOM" id="CLU_2508183_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3182-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9565" checksum="31464AF5C05690B0" modified="2008-01-15" version="1">MEQPSGLTYDPPASQLLSLQQAAAYTREYYPAQSLTEGTLRVYLNKGKIRGIKLDRYWYTTAAELERYLSQPTSATITQPSVTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B636</accession>
    <name>A9B636_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ordered locus">Haur_3611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3611"/>
    <dbReference type="EnsemblBacteria" id="ABX06247">
        <property type="protein sequence ID" value="ABX06247"/>
        <property type="gene ID" value="Haur_3611"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3611"/>
    <dbReference type="eggNOG" id="COG1521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066627_1_0_0"/>
    <dbReference type="OMA" id="HEPWLTL"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="112"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="28565" checksum="1592165C5BBB8A51" modified="2008-01-15" version="1">MWKSRMLITIDIGNTNSKIAAWDGDQMVAHWRLSTQRQKLTDEYAVLVRSLFELRGIAINQIEGCAISCVVPPLTSVFSELSRTYLNVEPVVIGPGIKTGMRLLIDTPRELGADRVANSVAAFRRYGGPVIAIAFGTATAFDVISTEGDYIGGAIAPGIGISADALFRAAAKLYHVELARPPRVIGKNTSHYMQSGIVLGYAGLVEGLVTRMWQELGTRGTVVATGGQAEVIADIIAGETHVIDHVDPWLTHEGLKMIHAMNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D9</accession>
    <name>A9B6D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0190"/>
    <dbReference type="EnsemblBacteria" id="ABX02842">
        <property type="protein sequence ID" value="ABX02842"/>
        <property type="gene ID" value="Haur_0190"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0190"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_251578_0_0_0"/>
    <dbReference type="OMA" id="WLRTEEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-193-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1414"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1446" mass="148940" checksum="369F8DCA908237C7" modified="2008-01-15" version="1">MNCPRCGTPNTPDRQFCGQCQAPLAVTPSASNDLPPWLQDLDQQQTVVPAKRGTSSLPPWLQEASPPPPVAANAESLPPWLQESAAPIPAPNVAPAPANSEELPPWLRDLQATAPALPADEPLPNAPRSEQPLPNWLSDLQSGSTPPPPTPVVNADVPSWLQGSVETTPPAPKPSANADVPSWLQEPALPAAPAPTPVAPSADVPSWLQGSVETAPPAPKPSANADVPSWLQEPALPAAPAPTPVAPSADVPSWLQEPALPADPAPTPAAPSADVPSWLQGSVETTPPAPKPSANADEEPMPAWLQQLRPSEPAPPPGIASFVEDNEEPVIARRGGTGNLPDWLKDFDTEPPVVQLSDVDLDAAGPSDDVPPWLKPATAPLTSPAAPAASSGVPAWMQADSAPPAPPAAPAASAGDDVPSWLRGDLDVVPPAAPAASGDVPSWLQAESAPPAVPAASAGDDVPAWLRGDLDVAPPAAPAASGDVPSWLQAESAPPAAPATSAGDDVPAWLRGDLDVAPLVAPAVSAGDDVPAWMQADSAPLAPPAASTGDDVPAWLREDLDVAAPAAPAASGDVPAWMQADAAPPAPPAASAGDDVPAWLRGDLDVAAPPAAPAASAGDDVPAWLRGDLDVAPAAPAASGDVPAWMQADAAPPVPPAASAGDDVPAWLRGDLDVAAPPAAPAASAGDDVPAWLRGDLDVAAPPAAPAVSAGDDVPAWLRGDLDVAAPPAAPAASAGDDVPAWLRGELDVAAPAASGDVPAWLQADVAPPAAPTASGGDMPAWLQADAGETVRLDSADASADVPAWLKADLEAAPPAAPAASGDIPSWLQADAGETVRLDSADASADVPAWLKADLEAAPPAASAASGGDIPSWLQADAGELPQVSPTVRLDPEDSSDNVPAWLKADLETASPAAPAPIDTPNWLHEDAPTVKLDNQAAGIPAWLQEDLPTVKLDSPAGNIPAWLQDDVTPIAPAPVKPEPVAPATPSYDPEGANVPAWLRDDLDIEIPASKPTVAPIIPSSTSPSWLLDDEPTQATQDDTLLGSVDLPAWLRQTVKLEEPSLVVEQEAASAVAESADWLRVLGEPEPAIAATSPTTRRLIDSEPPALLSRTPERVSAMHLLQDLVTKPLPEPVEAPPVALAPWWQRIGTQRIVASLMIISLLVGLLVPNLLAINTQALTIGGNTSDLYNYVETLNPESRVLIAYEGDLRHNAELGPLEHAISQHLIERKVPMLLLSTDTEGSLLASQRAAQFPVIDANTGYTGEGAEYLNLGWVKGNELGIAQLGSNLRGAIANLLLNREGADVNLLRIMSKLNSNNQLDRPRITTTKDLDLLIVVADEPGDVQRWMEQFWAREPALPVAILTTNEVLPQIQPYVDVNVNGTPAAIYTAAGLVGEQQYMALRSNNTNTNTNGPITALSLGMITTVVVVLVGGLLQLQRRIRGKRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K5</accession>
    <name>A9B6K5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0256"/>
    <dbReference type="EnsemblBacteria" id="ABX02908">
        <property type="protein sequence ID" value="ABX02908"/>
        <property type="gene ID" value="Haur_0256"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0256"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_7_2_0"/>
    <dbReference type="OMA" id="STIRCHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="78"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="17083" checksum="E53EA51CAD45A17F" modified="2008-01-15" version="1">MKRILLSMLVAVTLIGCGEIARPENPTAVPTSATTGVDISDVSAVIPALPNGLEVKQTASGLRYVDIVVGSGPEVTAGSTAEVFYTGYLKSDGSQFDSNVGGQPYAVEGVGGAMVITGWNEGLVGIKQGGKRRLIIPSALAYGEQGQGTIPANADLVFDVEVMTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6M4</accession>
    <name>A9B6M4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1690"/>
    <dbReference type="EnsemblBacteria" id="ABX04333">
        <property type="protein sequence ID" value="ABX04333"/>
        <property type="gene ID" value="Haur_1690"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1690"/>
    <dbReference type="HOGENOM" id="CLU_729142_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1714-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="371" mass="40414" checksum="D6EAB0A39BA568E8" modified="2008-01-15" version="1">MGIHDSFDDIGNQASSRRSFLRNSGLAALATAGALSAFDQAAANTKPAQSESIAATTGEIPASAQFARRAFRSLTLLAMSAVTSDTRFAQKVYGLALADLEINLAGLQNASDNVTSLSYTPNPDDDYEPRPWWWPRPWWRLKEQLFTPIERIPAGGLVVLDLHRSLDAFNMAFQYGDQTLQAENLRLARGELRSHLATLKGSSSFAAWEPGDDICPPWWPWPFPPIRKPSIPTSQPLLELGTLTKGLINYGLGQSMHNAALGRARSKAIIVQIQGSARKMAGYGGSLVGWEDGDDICPRWPFPWPGPWSLGQVLDQYSAEPEPLPWRPIASEVLRAGTIFAIASNLGDRGIAQGLRDAAIVQIQDQVAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P9</accession>
    <name>A9B6P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1715"/>
    <dbReference type="EnsemblBacteria" id="ABX04358">
        <property type="protein sequence ID" value="ABX04358"/>
        <property type="gene ID" value="Haur_1715"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1715"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080407_0_0_0"/>
    <dbReference type="OMA" id="TGYRVYD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1742-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="124"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="244" mass="27927" checksum="6FDCF128BB81C41C" modified="2008-01-15" version="1">MNVGRYFRTVDLAKAINVSVQQVRNYQAEGFLPNVERGSNGYRQYTQQHIDAIKTAHQLIKGYGWRNAQQIMAALHQANHQTAFNLINQHHAKLDSIRQQLDQTLTLLKAVADQLPPSPRHSQRILVGEAAKAVGVPISALRFWEQQGLLQPIRQASNNYRYYDERQLRRLRIIVLLRQANADFSSIRTTLETLDQQQPQRAVAAIEQRRVALAQQSWECLQATTALVSYIQTYVPLQPIPIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6W3</accession>
    <name>A9B6W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CinA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3194"/>
    <dbReference type="EnsemblBacteria" id="ABX05831">
        <property type="protein sequence ID" value="ABX05831"/>
        <property type="gene ID" value="Haur_3194"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3194"/>
    <dbReference type="eggNOG" id="COG1546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_1_2_0"/>
    <dbReference type="OMA" id="VEHALNM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3229-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="16207" checksum="540DA7B61E3BB82C" modified="2008-01-15" version="1">MSQALAQAVITALAQRQWTLATAESCTGGLLGDWLTNIAGSSVVYLGGIIAYANSAKQTLLHVPTSTLATVGAVSAETALAMAQGTAQALGATVGLSTTGIAGPGGGSPEKPVGLVYLGLHLPNQGLVEQHVWPYDRLGNKQASAKRALEWLLEQLSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B706</accession>
    <name>A9B706_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3237"/>
    <dbReference type="EnsemblBacteria" id="ABX05874">
        <property type="protein sequence ID" value="ABX05874"/>
        <property type="gene ID" value="Haur_3237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3237"/>
    <dbReference type="HOGENOM" id="CLU_1347377_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3272-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="22245" checksum="91606C7A81D6A6EF" modified="2008-01-15" version="1">MQLSMLEQMSTQNLYDLREQHRKNLSMLAQQAGQWGAGSVPAETQAQISQTQAMIEQINLVLGQRGHNHQTDPARGASLQAVLEHYRQQAPIQNTGTVNLNNSSVYGVVAGVNTGTITVNQQNGQAASSLQQAADMIQHLLPMARSQRSPFRHALSDAEVAVGDALKAQRNGNDPQRLIQQARADLEEFAQYPEVSQLLALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B744</accession>
    <name>A9B744_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="8" type="ordered locus">Haur_3275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3275"/>
    <dbReference type="EnsemblBacteria" id="ABX05912">
        <property type="protein sequence ID" value="ABX05912"/>
        <property type="gene ID" value="Haur_3275"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3275"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_1_0"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="146" mass="16247" checksum="64F5D0B0D6ED71AF" modified="2008-01-15" version="1">MPTINQLIRKPRKPVVKKTKAPALRFIYNSLKGKLTRGNGAPQKRGVCTQVKTMTPKKPNSALRKVARVRLSNQMEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTLDSQGVNNRKQGRSKYGTKKNAQVATGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L0</accession>
    <name>A9B7L0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_S9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0331"/>
    <dbReference type="ESTHER" id="hera2-a9b7l0">
        <property type="family name" value="Est9X"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02983">
        <property type="protein sequence ID" value="ABX02983"/>
        <property type="gene ID" value="Haur_0331"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0331"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_10_1_0"/>
    <dbReference type="OMA" id="LIHGGCW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-334-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="88"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="28772" checksum="5998275809C651C5" modified="2008-01-15" version="1">MSDSILAQAAPPADQRIWYGAEPLQFADLRVPPGIGPFPVVVVVHGGFWRARYDLEHIGHVCAALTALGYATWNIEYRRVGNAGGWPNTFLDVAQAADFVPNLAQHYPIDPQQVISLGHSAGGHLALWLAARPKLAATSPLWQAQPLGLKGVVSLAGVADLAMADQRRLSQQAVQELLGGSPETYPERYHDASPAALLPLQVPQIVLHGTDDGPVPFAISQSYVEQALAAGDEARLVPLPNAHHFELIDPASREWPAVVAAVQSLLATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q2</accession>
    <name>A9B7Q2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">H_lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1787"/>
    <dbReference type="EnsemblBacteria" id="ABX04430">
        <property type="protein sequence ID" value="ABX04430"/>
        <property type="gene ID" value="Haur_1787"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1787"/>
    <dbReference type="HOGENOM" id="CLU_699752_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1815-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037221">
        <property type="entry name" value="H-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019019">
        <property type="entry name" value="H-type_lectin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09458">
        <property type="entry name" value="H_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141086">
        <property type="entry name" value="SSF141086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H_lectin" evidence="1">
        <location>
            <begin position="334"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="394" mass="42405" checksum="94814F5E7EF0BD33" modified="2008-01-15" version="1">MAYNHQDKQSGQLIRAADWNEMSREVARLDEAKVNRAGGDTIKGPLNVTAGADAAQASLKVSATTNGPKAPLAEFRHSNQTQGVSIGYASILATGSNPNQPLAIAARGTDPLTLNAESGGNVGIGTTNPQNKLQVEGNLHLNGNSLYLRKGPADQFHLVRWQETSDRVEIGGFSGVTLGHTRDGANVIKPVLQVRSDQQVEVSGSLTVQLDAATRNVPILQVRRSAAAREDGKFVFLELFQEYAAALGEVYPSIRFHHGNRYWRRIEGRSDGFHFKDGDINSDGLTGLVASSLRFGDGTTQSTAVRVQGGYVDIGAFRGNNQVSQVRRAISYAGFTEAPSVIVSIVAIDSERGNNLRFHGFAESVTRTGCTIVAQTWADTIIYGSWVSWIAIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T2</accession>
    <name>A9B7T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M3A and M3B thimet/oligopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1817</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1817"/>
    <dbReference type="EnsemblBacteria" id="ABX04460">
        <property type="protein sequence ID" value="ABX04460"/>
        <property type="gene ID" value="Haur_1817"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1817"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021290_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1845-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="120"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="204"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="597" mass="69038" checksum="69D151E38FBD5732" modified="2008-01-15" version="1">MNTTQSFLVARWIRDDILPTDTETNTYQSYQQTIADLDRCVAQFELLRSSLDKSLSSEAVLQAIRDFETITTFIKRLSGYAELWIAEDTQNPHAQACATLIDIVITKATNKTLFFPLWWKNLPEDVAASILGDIPQYAYWLRQMRSAVIHTLPEPVEQAINLKNSTGVTALRALYDAITSRYSFTLEADGQIHHLTDSGIWGYASHPDPAVRDRAFVELYRVYSQDASLLGRIYFTLVQDWYQEYIELRRYSSPLAVRNQMNDIPDALIETLFRVCRTNTPLFHRYFRLKARWLGMERMRRCDLAAPIITKKQSYTWKQAVEMTLATFESFDPLFYQLAHRIFQANHVDSEVRSGKRRGCWCLDFGPTITPWVQIDFNGRVDDIAALIHEFGHAIHGMLAEHQSVLQYAPSIPLAEVGALFCELLFADHLLQQTHDPEVRIGLRFKQLNDSFAFLHRQIYFTFFECTAHDLIQQGASIDDVAQAYLDTVREEFGDTIDIPDAMRWEWTLIFHLFHYPFYMYSYAFGQLLALALYQQYRQEGNSFKDRFFEILRAGSSDHPVAILSKAGVNIADPLFWQGGYDVIQIMLEDIEQIPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B882</accession>
    <name>A9B882_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3799"/>
    <dbReference type="EnsemblBacteria" id="ABX06435">
        <property type="protein sequence ID" value="ABX06435"/>
        <property type="gene ID" value="Haur_3799"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3799"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_2_1_0"/>
    <dbReference type="OMA" id="DLNQKCA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3841-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="2">
        <location>
            <begin position="113"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="252"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="36972" checksum="73862790A734339F" modified="2008-01-15" version="1">MTYEFPPIGIAAIATYLPAAVETASQIALAANIPEAVVIEKLGIRQKHLAEAHDTPSAMAAEAARKALAIAELDPLDVDLIIYHGSEYKDYVVWSAAAKIQHLIGAKRAYAYEIYALCAGSPVAIKTARDQMRADPMLRNVLLVSAARENELVRYDNQQARFMFNFGAGASAMLLRRDYATNQVLESAVLVDGSFSENVVMRGGGARFPTSQATVDAGYHQLDVLQLEDMRDRLGLVSQPNFVQVIDQAVTRSGYRRSDIDFLAITHMKPSFHNGLLHDLGLRPDQAIYLDDYGHIQSVDQQLALDLAQQRGLLKAGDLVVLAGAGTGYTWAASAVRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B6</accession>
    <name>A9B8B6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3833"/>
    <dbReference type="EnsemblBacteria" id="ABX06469">
        <property type="protein sequence ID" value="ABX06469"/>
        <property type="gene ID" value="Haur_3833"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3833"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_0"/>
    <dbReference type="OMA" id="SMESDGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3876-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="29997" checksum="982A1362965203AB" modified="2008-01-15" version="1">MNEQRISIGNFAQATRLSLKALRMYDQLGILAAHYVDPQTGYRYYQAEQLATARLIGMLRQINMPLATIRQLINASAKDAEILLSRYIRSVELQAIQARRAQSLILGLIRQEGVCMSLEVTVRQQADQPILSITKRTFVNELDNVIAHAFHTMERFAADHHLVVRGSAFGIFHGTINADDDGPIEVCLPVDQLVESQGEIVGRILPAGKVAVVTMHGDQCEFPHILAGYDAGSDWVKANGYVVSDSPREIWINPPGPDALMEIAWPFHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T0</accession>
    <name>A9B8T0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07744">
        <property type="protein sequence ID" value="ABX07744"/>
        <property type="gene ID" value="Haur_5116"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5116"/>
    <dbReference type="HOGENOM" id="CLU_890735_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5178-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025855">
        <property type="entry name" value="Replic_Relax"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13814">
        <property type="entry name" value="Replic_Relax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="35140" checksum="8604B8A6826BD2AB" modified="2008-01-15" version="1">MKTPTGFAPNAMQTQCLVLLARLGRLLSRHLAVAWSPPCVPRHVNRAMQQLTEAGLVTYVDHFEAPPARGKRTTFWKRHGRIYSLTPLGWSYLKEGYPELEEGKERLAPTYFNPRHQAEHQIEYADLVTSILRDLDTIPGIIGMSSYIEMDLSEQARPRADGIVVLRRWKQAMLHTDERSSCYPWLVVPRQEGQIDELFAIEIDRGTEEPSIITGKAQSYGALYDSGSWKERFQWPIIAFAVPNERRQQVIFDAWYRGWPGGAIRCTTFDAIHAHGALAPIWTHQHHRDMTYQVPLLRAVWAEAVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B962</accession>
    <name>A9B962_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5249"/>
    <dbReference type="EnsemblBacteria" id="ABX07876">
        <property type="protein sequence ID" value="ABX07876"/>
        <property type="gene ID" value="Haur_5249"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5249"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_655172_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5311-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734634" evidence="2">
        <location>
            <begin position="27"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="304"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="419" mass="44681" checksum="35FAEC19DAD62908" modified="2008-01-15" version="1">MNERAIGSSILVASLIVLLACAPTYGDDDQPPTIVVNWQCPTPSPLPTIQSGVLPTPEPPINATYVPGQEPTAEAIYTTPLPTATPYVRTGSDYYVNQRIQINRYTLRVTSYRTQPASNGNAYHLVTLALENPTQTQWPLYLDFSQLRAIKGTDGRMIQATWYPSEEAAQQLGISPAKDPPLEEVGDTLVGGYPIGTSSRTLVFEAPAGDAQAWGITLTNEDTSRDDGAGSGQVWVLLRSDPNCTTGVGGGASEGGTIPTAGTPSTGSGRWPVPLDTPITRAFGCHGFFTGTRGPCGGATPWWHDGIDFAKPEGTPLYATRDMTVLFAGRDTSTIDCSGISGSRFPHFGFGNYVKTQDSLGFSYWYGHVSAWSVSAGQTVRAGQQIASMGSTGCSTGSHLHFRVRLNGLDRNPLDVISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B996</accession>
    <name>A9B996_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ArdcN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5283"/>
    <dbReference type="EnsemblBacteria" id="ABX07910">
        <property type="protein sequence ID" value="ABX07910"/>
        <property type="gene ID" value="Haur_5283"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5283"/>
    <dbReference type="eggNOG" id="COG4227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012069_0_0_0"/>
    <dbReference type="OMA" id="VPHEGMI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5345-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013610">
        <property type="entry name" value="ArdC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08401">
        <property type="entry name" value="ArdcN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArdcN" evidence="2">
        <location>
            <begin position="45"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="33502" checksum="B72CAF66E4597252" modified="2008-01-15" version="1">MNTNRKLLTADERQARDTERRSQLDVALMEGVQAILDSDSFKAVLAANAKFHSYSVNNAMLIWLQNPAAERVAGFHTWRKLGRSVKKGAKGIMIYAPRVATNVDAATGSEETHVYFGIEHVFDISQTEGDDIPTLDCPVLTEERGHDVYDRLVTYATRDGLTVSSDVAHELSEAMGYYSAVSKRIWVRPTAKAQMLKTLIHEIAHHLTEGKHTREAHETIAEGVAFQVCACLGIDSGERSFPYIAGWSASEGGTALIKQVLGHIQAITKQVMAIVEPADEANEGAPEPPPPAVAAAKRRRSTTVIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF8</accession>
    <name>A9AUF8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0426"/>
    <dbReference type="EnsemblBacteria" id="ABX03077">
        <property type="protein sequence ID" value="ABX03077"/>
        <property type="gene ID" value="Haur_0426"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0426"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_358915_0_0_0"/>
    <dbReference type="OMA" id="VIWENTS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-432-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734336" evidence="2">
        <location>
            <begin position="20"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="769" mass="84608" checksum="70E29BFB74DBCE4D" modified="2008-01-15" version="1">MRWIRWCWLLLLIALPISAASSQEQSNNGLVWQVEPVFGTVYRAGEWMALRVKVSNTGVDRMVEIHIGNYNVELDVPGGSQKETLVYGQFDQAFRVPMAMYLNGEKRETATLQLRSTDRPMVATLLEQPLPQLTKVVLVATDSQQLPNVQIGLDMLSGIVLNQRSWGELTPEQQQAIKQWVNNGGVLVAEPNLLEDLPAELQPAQATGQQTIATTTLSQVFGQPFNVPNLDVALLQPNQQAATSLKQEQTPLLVKRSVGRGFVIASAFNFDQAEITAWRGYENLLASLFPQQQDLGWMGAGSSESMLRDSAAPALLNNLPALDLPPLQTLLILLGIYIVLAGPVTYLVLRRLDRMALAWLTIPTLTLIFAVLAYGIGSKQRGTDILVHDVALIYPDEQANATVLGYAGIFSPVREDYQVTINHGAYPRPLLVNPNLGTNGGINATRALYSHQPGDVRNLTINQWSMEMFAYERDISDAPHVQIEISLQGKKIIGKVKNTSTYTLSDAAFIMLGNAQKFGTIEPGAEKSIELQINNNPSMSGASYLLFQKELDEGYQTEFGPPRELLAKTQALDIALPTTYGSIDRNAVFVAFVDFNQAVIDLPEKRFAATQRSLLIQYPQLRYSQNAVELTNNWFSYILEDDPNMGMGSTCTTSARGAGTNISQKTGIIQLSLPTTFSSIEAQSLRLLPTIDGGMVAPNKLTYELYNWATSQWDVVEFKNGAIDLTTSPSTYLQQGNLRTRYTLDPTVDTTAGLWGCFSVGPVLSGVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL2</accession>
    <name>A9AUL2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1896"/>
    <dbReference type="EnsemblBacteria" id="ABX04539">
        <property type="protein sequence ID" value="ABX04539"/>
        <property type="gene ID" value="Haur_1896"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1896"/>
    <dbReference type="eggNOG" id="ENOG502ZB9P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075044_0_0_0"/>
    <dbReference type="OMA" id="LPIAVWE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1925-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="35171" checksum="A739E5EFDB648ED7" modified="2008-01-15" version="1">MANQSNSYQIQIKGQLDQRWAEWFEGLAISQTAQGDTLLIGEIVDQAALYRILRKIRDLGLPLIAVVPLNQSILPTEGAHAMQNQRRNAILIGIYFILAAVTSIVGLIMYGPLLNQSDYLVAGAANGNQIVFAALMELGLVVTAVGTAVTMFPILRQYSERMALAHLCFRFLEAVVITIGIVSMLALLTLSREFSSATAPDEQSYRVVGTALIAIHDWTFIIGPNFMLGLNTIMYSYIFYRTRLIPRPIAIIGLIGSNTVFLAALLELFGVIEQLSTWGAILAIPVALTEMSLAIWLIIKGFNANPTIKQSSSSQFVLSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM9</accession>
    <name>A9AUM9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1913"/>
    <dbReference type="EnsemblBacteria" id="ABX04556">
        <property type="protein sequence ID" value="ABX04556"/>
        <property type="gene ID" value="Haur_1913"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1913"/>
    <dbReference type="HOGENOM" id="CLU_823289_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1942-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="3">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="35521" checksum="746407CEAF708F77" modified="2008-01-15" version="1">MNCGDIRLQLAQHTALTPADAVAIEAHLTTCDACRLLVADLETQTEQWFELLGKTTAYPPVALRVATRSRLIGLTNNAPRFGQSRRLLALGFAALILIGCVWFASIRWFLPATERGLEQAYNGTSLATVTQFIAEKPATPTLTPASQHPERLSTTNPTKVAHPLETAITISPIIANPLPTQVRPIVPPTQALPAQTMIPIVTQEPLPTTMPQPTEEPSTAVLPTTIPIVPSQELSTAIPPTTAPVLPTTVPQAPQLPTAIGTPNPPTAIGTPNLPTAIGTPNPPTAIGTPVMPTAIGTPNPPASPTATSKVVPSPLSTTQLLSPTPTSDDQRTNRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUT2</accession>
    <name>A9AUT2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06520">
        <property type="protein sequence ID" value="ABX06520"/>
        <property type="gene ID" value="Haur_3886"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3886"/>
    <dbReference type="HOGENOM" id="CLU_695936_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3928-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735232" evidence="1">
        <location>
            <begin position="23"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="396" mass="42390" checksum="4F65BE6809B91A81" modified="2008-01-15" version="1">MHIRLFSGLLSLLLVAGCGSQAAQPTITPPPTLTTAAQVEVIATASLAPNEPTAELATPTLDDPNALVDTSMLTGRIYFIDPLGFAINSITPTGGDLQTAYKEQGSLPLSRLGIDPSLHYLSVFKGDFLHIYTTDFQELLRLPSSFEPIWSPRGDGKFALLKLTDMGEAFVDVYDLNSATPASTVVSTIGYRAAWLSDGLGLLVHNGNQIGTANLDDGAFSPILELVEDEHGTWAVDELLSYADQIYFHGGQVNLLGASGNGMQWWAVVDGAPQAVTDIGGNGILRLQFNQEREQIAFIDNFHISACLGAQVLSVQAPDFSAPARNPNLSPILADNGQAIHGAAWNPTGDWLTFAKGDYSCDEAGPIYATPQVLVWNPATQAIQAFEYGSYPVWIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVD6</accession>
    <name>A9AVD6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1984"/>
    <dbReference type="EnsemblBacteria" id="ABX04627">
        <property type="protein sequence ID" value="ABX04627"/>
        <property type="gene ID" value="Haur_1984"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1984"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_317312_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2013-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="671"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="959" mass="105597" checksum="4506C401D3ECB75F" modified="2008-01-15" version="1">MLATPLPMFARIIRLVDQRPLSALVIAHRRLLAMESSACVDHGWAWFCYGWAALHGEKVSEGLAALQQAQALFAQHHDQAGMWDCRQALLVGRWLQGEGVSLQQAWQPVIEAHLRLGGARAAAEAQIYQLIHLNYLKRYQAVLDLAATIAPHLTTAPQFVAGRFMRIVAIANAGLGAFTKAKQGLDQALYASQQAKAWVDVAKCLRERGFIADRQEHYADAVADLQQAMTWFNRLGMPLYAALCQRALGLALSRIGHYDQGLRFNLAARSSFRMLDRPDLAAGCDQNIGVIAHYVRLPLIAQSAYQRALAVYQARSSTYDSCVLQRNFALLQINQGNGQLALDLLGAIQPLVLALDDQLELGEFYEALAQAWHCLGAVDQAQRFFDQAIVCFEAIGNQINIAKCQLGQAWLMLETGNWQLAQALLAQAQVWLLEHPTHRWRCHYGLGYCAAQAGASGRAMAEYIAACGIVAQLRQALSSEHASSAIFAQAQQLYHDTIRLALAQANSNLAWQLIEQQRALVLNRQMRCLPLAFDPDLAEEDQRYHARLSSLTQPTAGHEHVEALFADYINFLIQARHTLEGSLADLAIDRPLEVVCGELDEAFDGDWTWLGYSQLGDDLLIITLYAGQITVIRQPIDRRFCELLGLANSFTDHSILYEDWSFLSQAAPFAELRALSDRLIPSVVKQRLHQNHRLLITPCTKLHQVAWAALLVNQQRLCQTCIPQIIPSLGTWSWLQARQSLGTEALLLGCDNFGERADALPHIQAELRVVAQQVTIPVSTLFGAEATGVAVLKLGQAGLLQRFRHIHIATHAQLIAARGLLAHIKLVDGDMFYNDILNLRLAGATVVLSTCDGSLSETLLGEEVLSLSRAFLAGGAREVLANGWKTSDSGVVELMRLFYHYLAYPNDGATALAMAQRTLLESDDPSQAAVLVWGGFQVVGAGTLAQWPSAQIPSISVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK2</accession>
    <name>A9AVK2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2052"/>
    <dbReference type="EnsemblBacteria" id="ABX04693">
        <property type="protein sequence ID" value="ABX04693"/>
        <property type="gene ID" value="Haur_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2052"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_44_1_0"/>
    <dbReference type="OMA" id="AKYDMTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2080-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9663" checksum="4C042AD955D7DE13" modified="2008-01-15" version="1">MAKLMIHNRIRHLRVEAHGMTQQALADHVGITRQTVIALEQGRYYPSLELAFRIALLFGTPLEQVFQVDRTIEIHDAFIQPQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN5</accession>
    <name>A9AVN5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4003"/>
    <dbReference type="ESTHER" id="hera2-a9avn5">
        <property type="family name" value="A85-IroE-IroD-Fes-Yiel"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06635">
        <property type="protein sequence ID" value="ABX06635"/>
        <property type="gene ID" value="Haur_4003"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4003"/>
    <dbReference type="eggNOG" id="COG4947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090325_0_0_0"/>
    <dbReference type="OMA" id="NREYHRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4045-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="239" mass="27899" checksum="5AF50CCF49C7A33F" modified="2008-01-15" version="1">MHRSYHRWHSSALGRDMELLLFGHHGAPVLVFPTSMGRFFEFEDRNMTGILAEHLERGWLQLICVDSVDAESWYCKWAHPSGRIGRHLQYEQYLIGEVVPWLRNFNQNQFLMSVGCSFGAFHAVNIALRHPQLFRRCLGLSGRYNMRSFMDGYSDEQVYFNTPTEYTANLHDSGQLAHLRQLDIILAIGRDDPSYQSNEVLSSNLWNHGVGNALRVWDGWAHDWPYWEQMLPKYIQGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ4</accession>
    <name>A9AVQ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4022"/>
    <dbReference type="EnsemblBacteria" id="ABX06654">
        <property type="protein sequence ID" value="ABX06654"/>
        <property type="gene ID" value="Haur_4022"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4022"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396328_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4064-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="421"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="455"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="489"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="628" mass="71550" checksum="04CB00BBBD648C7C" modified="2008-01-15" version="1">MTSNTKQLIIWVGNAGEQRTQAAQAWLADQTAARTWLLSMNRANLGHWAGLNSFVSSLLPAIKAQAPELLVKYDYELALVLPQLQRELAVRNPSLTDISNPQERTRNYAADRAFRIVQGLIDLVHEFRQTAPDQPWVIVCDQFDQAGSLVTMFFKELLRRADPRMSLTIGFLVEPNQPELLNEYHSWHAHVEVVQGAWQADPPIVIDPAEAKRQLEVLEREHTFDPIEIELHLPQLIQLATAANEPRKRLGFMHEGLSICSTRGLYADALYYGEPLRVAMEHEFPKSVDFRLSAYLKLYNCYIGLKQAEPALDIAETAVSITDNPARLYSWYYLIAMIHARFAEPRDFDKAEYYLDLGIEAINKADIPAHEKLFQSSFNRNGLALIRHFQKRPLEAIEICQECYKNLETGLDTEDHKLHRSVLLYNIAQVYDSLKDYPKAIEYYSLTIEMDPNYAEYYNERANIYLHIGDYAAAERDYQRSIELSPPYTEVWTNLGQCYQVQEHFEKAIGAFSRALDIDPKNVVALNHRAECYEGLGQTQAAIADYSASLKLKTSEASTFANRAILYYELGEIEASLADLNTAISLQPDLAELYENRAVALEALERHAEAEHDRQQAILLAKAHEVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU5</accession>
    <name>A9AVU5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4063"/>
    <dbReference type="EnsemblBacteria" id="ABX06695">
        <property type="protein sequence ID" value="ABX06695"/>
        <property type="gene ID" value="Haur_4063"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4063"/>
    <dbReference type="HOGENOM" id="CLU_2788199_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4106-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="68" mass="7806" checksum="1AFC236BBAB02F0D" modified="2008-01-15" version="1">MRRRKPQPLNEQRREVLLWLAQRGWTLAQLAAASGCDSAILRAWLEGKRSLSEAERLAIEEALTSHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW5</accession>
    <name>A9AVW5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0555"/>
    <dbReference type="EnsemblBacteria" id="ABX03203">
        <property type="protein sequence ID" value="ABX03203"/>
        <property type="gene ID" value="Haur_0555"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0555"/>
    <dbReference type="HOGENOM" id="CLU_1893321_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-564-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14325" checksum="5319C3816EA66A35" modified="2008-01-15" version="1">MLPMRPTEFTVMQATHTDAMRDQCVLMEPQTSAGRNNKPVITYTDAGSSACGFNPSTANGVASEEVLDSTAVVITKPTLRLPAGTVIRASWRVRITHRNGQVLTPALTFEVVGDPATLGTAIVVELATVTREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW46</accession>
    <name>A9AW46_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0636"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03284">
        <property type="protein sequence ID" value="ABX03284"/>
        <property type="gene ID" value="Haur_0636"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0636"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028014_0_1_0"/>
    <dbReference type="OMA" id="WWPEPAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-645-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="67"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="389" mass="43856" checksum="37FC353199BFE38F" modified="2008-01-15" version="1">MQPASLSVLTPTPVYPAHAGSKNYSLNAVQQLSHYYTVDSYCLATQPEAVDWGPLPQWCRDLRAFTPTKPARKGIDPPAVHLEFSQPMCDYLQQRWMRNLPDLLQLEGTTMAQYAPFARRLGLKAIICTIHQVGFVAQWRRLQREHHWKLRARRLAGLLSLWLYEQRALRQCDLLVTLSTTDQQTLNRWQPKLNVVTVPAGVDLSQWPLCRQSQAPQQVLFVGNYFHPPNVEGALWLAREVWPLVQAQLPEARLMLAGRSPTPEIQQLASATIQVPGTIDDLQAVYRQSQVVAAPIFWGSGVRIKILEGLATGLPLVTTTLAAEGLPLKHEEHALFAETPQTFAAALVRILNSPRLAEQLGEAGRQLIAQQYDWQAIGRQLAQHYQKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWB3</accession>
    <name>A9AWB3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two component transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2123"/>
    <dbReference type="EnsemblBacteria" id="ABX04763">
        <property type="protein sequence ID" value="ABX04763"/>
        <property type="gene ID" value="Haur_2123"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2123"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_5_0_0"/>
    <dbReference type="OMA" id="ERFCLEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2151-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="314"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="46355" checksum="9A0BB85702250920" modified="2008-01-15" version="1">MTYKVFLVEDEIIAREGIRDAIDWAAAGYQFCGEASDGEIALPLIRERRPDILITDIKMPFMDGLQLCRIVKETLPTTKIIILSGHDEFRYAQEAMQIGVTQYLLKPIVAQDLLAALRKIASQIDGERQAKAQLETLQAQMFDHQPMLRERCLLDLVSGSSSAADFMEQARNLEIDLLAPWYQVLVMHAMPPSAATAPLYTLYQQVDVTVAASLNQSPLVVAFKHGLEDTILIVRGETRADMTQQAERLATAMRQRVAEQLGCRAIIGIGDPTERLSLIPQSFAEALAQISSFERPAESDPSDQGQFHGGAIMLKALAYIDTNYADPAMSLGQAAAHVLLSPTYFSALFRREVGETFIDYLTQVRIRKAIELLRSTSLTASEIAYRIGYQNPRYFYSVFRKVVGQPPNEFRQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF8</accession>
    <name>A9AWF8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4085"/>
    <dbReference type="EnsemblBacteria" id="ABX06717">
        <property type="protein sequence ID" value="ABX06717"/>
        <property type="gene ID" value="Haur_4085"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4085"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_18_3_0"/>
    <dbReference type="OMA" id="WDAFWGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4129-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="14107" checksum="07128D6C0B49D43D" modified="2008-01-15" version="1">MFDMIGIVVADMAKALDFYRLFDLDLPSDPGGEDHVETTLPNGMRLAWDSQTLMKQLQSDWQEPRGHRMGLAFKCASPAAVDQLYAKILAAGYRGSKEPWDAFWGQRYAVVLDPDGNLIDLFAPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG4</accession>
    <name>A9AWG4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4091"/>
    <dbReference type="EnsemblBacteria" id="ABX06723">
        <property type="protein sequence ID" value="ABX06723"/>
        <property type="gene ID" value="Haur_4091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4091"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4135-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="122"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20906" checksum="E65619624552FB52" modified="2008-01-15" version="1">MLIGGTTLTRAGMRSVLAEYEAEIVAAASSIEPLIEQLGVVDVVILLDDQALPLLLQQTNDQPAILLISQELPHPMPQQRAWGVVSTDAYPQEIWASLQALQLGLCVLSPSILAQIHSPPQPEPLDNQLSEREHEVLQLLAEGLTNRQIAQRLIISEHTVKFHVSALLGKLDVSSRTEAIRVGAQRGLIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR5</accession>
    <name>A9AWR5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0668"/>
    <dbReference type="EnsemblBacteria" id="ABX03316">
        <property type="protein sequence ID" value="ABX03316"/>
        <property type="gene ID" value="Haur_0668"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0668"/>
    <dbReference type="eggNOG" id="ENOG502ZE33">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1203503_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-679-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="26509" checksum="0995998AFBC3472E" modified="2008-01-15" version="1">MATTNKKPKVFSWQPMDLLPNPSIKINPPEAASWLRTLEPFVFQANHDNNAVARIPKLVNEEVIYIYYDPSQKRTIETEPYNYEHRQLHETPSISKQVLRWLNKDKDHFDHIHQAIEKSRFMLELEDNWDEEGSVGYKEDTWIKAVNLLLDMVKQYFAMNNQKIPTPIIGLGPDGSIDISWKHSNKHLLINVDATDDLVTYSGDNAADNSLSGSFDLSEGGLWLLVWLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV6</accession>
    <name>A9AWV6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine--scyllo-inositol transaminase</fullName>
            <ecNumber evidence="4">2.6.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.50" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0709"/>
    <dbReference type="EnsemblBacteria" id="ABX03357">
        <property type="protein sequence ID" value="ABX03357"/>
        <property type="gene ID" value="Haur_0709"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0709"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_6_0_0"/>
    <dbReference type="OMA" id="IVNHGMY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-721-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047310">
        <property type="term" value="F:glutamine-scyllo-inositol transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080100">
        <property type="term" value="F:L-glutamine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="39681" checksum="B5622E26ED0D6931" modified="2008-01-15" version="1">MSIAFNDLGRHVATMAEEIEAASTRVLRSGWFVLGPEVRAFEAEWAEYCGARHCISLATGTDALILGLRALGLQAGDEVLTVANAGSYTTFATHTVGATPRYVDVDPVSYTLDPSQLAAAITPRTKVIVPVHLYGQVADLSAILAIAADHQLPVLEDCAQAHGARYQGQHVGTFGALATFSFYPTKNLGALGDGGAIITNDDALAAQIKQLRTYGWSSKYQVTIEKGTNSRLDELQAAILRVKLAHLDAQNARRQALAARYNAGLAATPLQCPQLNTAQHVQHLYVVRVAADQRNALRQHLQAAGIGSDVHYPIADHQQPAWAERYQDVSLPITEALSNEILSLPCYPELSDAEVDQVIDCIQAFFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX05</accession>
    <name>A9AX05_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2173"/>
    <dbReference type="EnsemblBacteria" id="ABX04813">
        <property type="protein sequence ID" value="ABX04813"/>
        <property type="gene ID" value="Haur_2173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2173"/>
    <dbReference type="HOGENOM" id="CLU_1439272_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2201-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="22159" checksum="25F431F38D1C3536" modified="2008-01-15" version="1">MGVRQSFVRITAEQLAELEQIAIEHSSLSYAEISPQLYQVLDRRSHLQQYTMVPLDKLSPEQAYYKFTIEKSYWSLLEDLMVQLIRDQVVDWWPIHEDYPVHIGDLWPCYSYIYLIFHHELAPLLDLLQHVPYEQLKQAFDADFAEFTDMTVEEKQGVYNVVLSCLDSIRIMAQQAHAANESIIWYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX13</accession>
    <name>A9AX13_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="2">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2181"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04821">
        <property type="protein sequence ID" value="ABX04821"/>
        <property type="gene ID" value="Haur_2181"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2181"/>
    <dbReference type="eggNOG" id="COG3934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537241_0_0_0"/>
    <dbReference type="OMA" id="WDIKNEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2209-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="entry name" value="PTHR31451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="6">
        <location>
            <begin position="244"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="568" mass="66060" checksum="9E1F808309D58CA9" modified="2008-01-15" version="1">MWFMSQRRFKIIIWLLFLLILGQCGWWGVGRVAWLVASFQQGADPASALKLPPMLPPEAAIATQWLPDDPDTGRVMEDFTRQQLTSDYGRAWLQWNLSLKIGRPYNLHTSFSGPALHYLTTSISTTENIKIDQIDTAHQLQLHFYAADGSIVALTDTQAEIYQMIYDADGEIVSAQWLYARYEIVMLLQDGTWRIRHWVRHELPTPIEPSYQPRPQLLQVNQQQLQLADQPFIARGVNYYPSKTPWLQFWPAYQPQQTTKDLALVQQLNLNSVRIFIPFEQFTEPYSTSLYLRSVTDFLDQADQANIKVIVTLFDFLGDYQLARWQATDSYLTTVVTALREHPAIMAWDVKNEPDRDYATASQVVVEAWLQHSIRQLRRLDPHHLITIGWSTPEAAERLYQDVDLVSFHYYGSTELLATHYQRLRQVVGEKPLLLTEIGMPTWNSPFFPHGHNQREQANYLTGLMQQAEAYNGFLIWTLFDIPEVPKAVAGFWPWQRGPQTQLGLYNETYEPKLISKVLLGLEPSPFIRWWEAWLKPFRITLIVLSMLGLIGGWQGYRRWKRKKHPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX40</accession>
    <name>A9AX40_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2208"/>
    <dbReference type="EnsemblBacteria" id="ABX04848">
        <property type="protein sequence ID" value="ABX04848"/>
        <property type="gene ID" value="Haur_2208"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2208"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067347_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="31632" checksum="28F777218C448337" modified="2008-01-15" version="1">MTLVKRSTTNLVLAADAAIDLQLHTTASDGQWSALNLIHHLKREGFGLAAITDHDRPDMAQSMQDLAVAEGMPLLVATEMSCLWREQLVDLLCFGFELGPNPLMAIAAELYQRQQAIIAKAFAYCCDQGYLTQQHQAQIVEILAQPSAQQPHLLAALVKQQNPTLAPAQFSQLIQASGCDFATNPIAAVVAAAQQSGAICILAHPGRSDGFVCFDQALLDALRAEVPLDGIEADYPLHTAEQAALYRSYAQQHKLLISAGSDSHSPNKPPIRYRAADYQALLERLGIIVQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE1</accession>
    <name>A9AXE1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase D/Transphosphatidylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4229"/>
    <dbReference type="EnsemblBacteria" id="ABX06861">
        <property type="protein sequence ID" value="ABX06861"/>
        <property type="gene ID" value="Haur_4229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4229"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038053_0_2_0"/>
    <dbReference type="OMA" id="YVHVEFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4276-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="417" mass="47814" checksum="B81D6320B5B76065" modified="2008-01-15" version="1">MRWLKAGLWFLTEWVLSLPRLLLASILAQLGLMGALMAYAKLRNRSVENSFPQLDLPPIDLGEHSVQLFDDGGSVFRQMLFDISLAKESILLESYIFERDEVGLAFKRALIRKAREGVKIYVTFDGIGTLHVPERFKLFGKRRNIRVFEFGRLKSIRSFFDTNMWIRTHRKILVIDGKIGYLGGMNIGRNYARTWRDTHLKIEGPIAANIAEEFIALWNKYNKKHKINLSYATTSDQQVGICANDPIEYQLPIRQTYLDAINDAKHYIYISNAYFLPDPLIRATLIDAAKRGVDIQIMVPEISDNIVVDWICRGLLGELMEHGARVLLYRGTMIHAKTMTVDGLWSTVGSANLDTRSLAANYEINATIKHPAFARQMEAMFLNDRAQSREINYQTWRSRSIFIHLGEQVLQPARGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR7</accession>
    <name>A9AXR7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0833"/>
    <dbReference type="EnsemblBacteria" id="ABX03481">
        <property type="protein sequence ID" value="ABX03481"/>
        <property type="gene ID" value="Haur_0833"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0833"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_7_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-847-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17188" checksum="929BAB5E1A1EC18D" modified="2008-01-15" version="1">MAQYLYGDRIAAQGRLMLGCSATLFDATRSKLLLTRRTDNGRWCLPGGAVDAGESVSEACVREVFEETGLTVQVVRLLGVYSNPHRMVRYADGNQYHVISMNFEVSLISGELGLSNETTEVGYFSQAEIDTMDLIDPHRERMPAIWSNDPIPTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXZ4</accession>
    <name>A9AXZ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2320"/>
    <dbReference type="EnsemblBacteria" id="ABX04960">
        <property type="protein sequence ID" value="ABX04960"/>
        <property type="gene ID" value="Haur_2320"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2320"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_0"/>
    <dbReference type="OMA" id="QVMRYFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2348-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="173" mass="19759" checksum="4FC061239B599527" modified="2008-01-15" version="1">MVDDRQILETERLILCKLTPDDLEALFRLYRDPIIREHFPEGVLSREETQAELDWIIKVYYGDYGYGLWATIYKPTGAFIGRCGLLPWVIDERQEVEVAYLLDQAYWGQGLASEAAQAIVAYGFDQLHFDRLICLPIPENAASIRVAEKMGMQLERELVLDGSPALLYSIAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY77</accession>
    <name>A9AY77_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transport/detoxification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4327"/>
    <dbReference type="EnsemblBacteria" id="ABX06959">
        <property type="protein sequence ID" value="ABX06959"/>
        <property type="gene ID" value="Haur_4327"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4327"/>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_13_1_0"/>
    <dbReference type="OMA" id="HCVNAIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4380-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="8075" checksum="E6FB4C704B4A87FC" modified="2008-01-15" version="1">MKTESFNVPGISCQHCVNAINNEVSAVAGVQNVVVDLASKIVKVESNEQVSRDQLLTAISEAGYDVSPFANTIPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB3</accession>
    <name>A9AYB3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0847"/>
    <dbReference type="EnsemblBacteria" id="ABX03495">
        <property type="protein sequence ID" value="ABX03495"/>
        <property type="gene ID" value="Haur_0847"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0847"/>
    <dbReference type="eggNOG" id="COG4034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_800915_0_0_0"/>
    <dbReference type="OMA" id="DAHHGVN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-861-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010581">
        <property type="entry name" value="DUF1152"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06626">
        <property type="entry name" value="DUF1152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="37600" checksum="87643AADBC850398" modified="2008-01-15" version="1">MQLNLPILDQLQGRRSILIAGMGGGFDIFCGLPIFLQLRQLGFNVHLANFSFSDLEAASNLQYLGDTVYGVPSLPRDPEFVPSHSPIDATQVALFQRYSPFIYFPELYLAEWFRQTYGEPLTVWAFLRSGVKPLLASYRRLVQHLSIDAIILIDGGVDALVQGDEAEIGTLVEDTISLAAVNQLNEVPTKIVTCIGLGAERDMHYPHIFQNIASLAESEILLGTCSLIKQMPVYQAYAAAVHWTQSRIYQDPSVINSSIISAVEGYFGNYHLTSKTEGSKLDINPLMSIYWFFDLVGLAEQHLLLEPLLETEHLREVVQWVHTLRANLPIRPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE6</accession>
    <name>A9AYE6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0880"/>
    <dbReference type="EnsemblBacteria" id="ABX03528">
        <property type="protein sequence ID" value="ABX03528"/>
        <property type="gene ID" value="Haur_0880"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0880"/>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873440_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-894-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="33896" checksum="EACFEE91579D57E7" modified="2008-01-15" version="1">MTETPYSTHVAGSASGSTDTTQRQAWIIVLIAALVGLGLAIVWSFEVADHVLGANIANTIVGADAKELVLDSSSLLSGVIFSIAAGLAATFTACNCVVFSCIAPLTAGKSTMSLWRTLGWMTLGILLITGSYGIIGTLLGEKLPILNNATLPIGKGYPIRLAQSSFIFVGLGVIFVWWGLHTLQILPNPLAKLFARNPWFKPFGLGLLIGCFTIGRPFGLFRKAFSNAIVAGDPFFGGLAIALQGLSNILIMVLVLLGLIYATGGRFERWLSANPSRITRFTAISVIVGGIFFIAYWGLRVPSYYEIGWFPHMSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYG0</accession>
    <name>A9AYG0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ordered locus">Haur_0894</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0894"/>
    <dbReference type="EnsemblBacteria" id="ABX03542">
        <property type="protein sequence ID" value="ABX03542"/>
        <property type="gene ID" value="Haur_0894"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0894"/>
    <dbReference type="eggNOG" id="COG0041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094982_2_2_0"/>
    <dbReference type="OMA" id="SNSIDGW"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="16975" checksum="4EBB9AB5F68F5725" modified="2008-01-15" version="1">MSAVVGIVMGSDSDLTTMQAAATICQEFGIGYEMRVVSAHRTPALMAEYGQTAHERGLKVIIAGAGGAAHLPGMLAAYTPLPVIGVPVPIGHLQGVDALMSIVQMPGGVPVATVAIGQAKNAGLLAIQILATADAALQAKLIEYKQTMAAESQAKNERLQTTINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN7</accession>
    <name>A9AYN7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2375"/>
    <dbReference type="EnsemblBacteria" id="ABX05015">
        <property type="protein sequence ID" value="ABX05015"/>
        <property type="gene ID" value="Haur_2375"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2375"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174488_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2403-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="97"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="30952" checksum="1738B6986B3A69FE" modified="2008-01-15" version="1">MNRFDDCGDVVRKSILHLNDCEQWMLNASQIDEYIAVITRLYPELPDNLELLSKWISNYHFEHRLIQALADQSHPDHGRAWNDLIRQIANQLAPKEVYAYGDRQTIMSDLIQETCLLIFKSINQFKYKSRLRTWVYTIVNNQYLQYVRKLKTRNQLKPDQSIDDEIGLELADRNESLESVVDFNLLHQHCIAILRQAPDPRLADIFQYYAVEELTLKQIAAKEGLSIGRVHELFKKIQTILYTDPIIIYWRNDAATSDDSAEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYZ4</accession>
    <name>A9AYZ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4402"/>
    <dbReference type="EnsemblBacteria" id="ABX07034">
        <property type="protein sequence ID" value="ABX07034"/>
        <property type="gene ID" value="Haur_4402"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4402"/>
    <dbReference type="HOGENOM" id="CLU_1123338_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4456-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="27396" checksum="B5A217AADCFB0E02" modified="2008-01-15" version="1">MQTMWMLAAGDLLTFSLTTAALWWLTSMIGLMDAESGYLAGLGALMISFGGALSSLNRFSRLAMGQSLFGWSIDLFQFLTPGFVCLAYGLWYGQQALRLRRTTQIWLAPMLTIFAIQSFAALMIGRQNGPSQFIVLLSFTSIASFTMIGLCIRQARWQGLRTVIIFSAAYLTMISSMNIIAHSFNEQNDLMISMVLTTNMLAALCFAGAGWILYQSTKRRQQIQRIMAMLDDSLAQPKLNGRAGPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ29</accession>
    <name>A9AZ29_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4437"/>
    <dbReference type="EnsemblBacteria" id="ABX07069">
        <property type="protein sequence ID" value="ABX07069"/>
        <property type="gene ID" value="Haur_4437"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4437"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105789_1_0_0"/>
    <dbReference type="OMA" id="LAWHEEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4492-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17695" checksum="9BDD73B3CC7688C3" modified="2008-01-15" version="1">MLTASERDALVATILHLPAQLHALVDRLDLEQLNTAYISNEWTIAQNIHHLADTQMTLFIRIKLLLLEDYPTLKPFDQDTWVTTVDSVGPIETSLTILQGLQERAATLVNSLDLASFERTGWHPENGETTLEQVVRYYARHGELHLEQIGQVLAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH4</accession>
    <name>A9AZH4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2480"/>
    <dbReference type="EnsemblBacteria" id="ABX05118">
        <property type="protein sequence ID" value="ABX05118"/>
        <property type="gene ID" value="Haur_2480"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2480"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558814_0_0_0"/>
    <dbReference type="OMA" id="SNVGNRD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2508-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013489">
        <property type="entry name" value="CRISPR-assoc_prot_Csm6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09659">
        <property type="entry name" value="Cas_Csm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="480" mass="55390" checksum="EE898CA2F35B5587" modified="2008-01-15" version="1">MQRIAFCNVGNSDVAVQGAIIRPSRPAGEHHWQTYSEHQFSAPIIDAFARYFQHRQLMIDRLIMFDTDQADTPASSVKDRNNVSLRDKDTCWFGMILERYIQEHWSHVIRMVERRTIYDVNPSLYDDAMQAFGQQLANIKHQPETEYYVLAAGGTQAFNNALQFKAIARFREACFVLYKSEHDQWPYSLNIRKQLLNSFNISTPIQLIQQHNFLGAITLLEGSVEPGIIGLLRYAKYREDFDFDSAQQILAQIQFDVDGSLRDLVRSIQHTAYQINQADLKFLLVELYYNAQIAYTNGRYADFLGRMFRFQETVLRYLVETTFKLSTDYSKAHKAENLAKFNQLLVDDPTLHAYLEQATLGDQKLDYQHFSVPVLIAMLNFASEKAGQRYLSKQQAGLCIGILKNLHKITNLAQMRNQSIIAHGFQGVSKEKINEAMQLKLEQTPLDILRDILSKMQLDLSESPFQQIQTTLTQKLYSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ0</accession>
    <name>A9AZJ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2496"/>
    <dbReference type="EnsemblBacteria" id="ABX05134">
        <property type="protein sequence ID" value="ABX05134"/>
        <property type="gene ID" value="Haur_2496"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2496"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_4_0"/>
    <dbReference type="OMA" id="HTYDLGR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2524-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="112"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="20697" checksum="22CC24BCC52BD7CE" modified="2008-01-15" version="1">MIIPYVHTTERETAVTQVISQWFDDHHDAMFRYLTRIVGQPEQAADLVQETFLRAMKVLDPTLLPAIPQAWLFRIASNLALDHLRRQRRWSWFMRSWQPETNNFDQHVETTQAIRGCLAKLKPQDAEVLLMVHYAGCSPAEVAKLNGEELGAVRKRLSRARDRFRNLYEEERGHEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL8</accession>
    <name>A9AZL8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2524</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2524"/>
    <dbReference type="EnsemblBacteria" id="ABX05162">
        <property type="protein sequence ID" value="ABX05162"/>
        <property type="gene ID" value="Haur_2524"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2524"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_3_6_0"/>
    <dbReference type="OMA" id="RHGKRWM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2552-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="9">
        <location>
            <begin position="76"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="537" mass="59202" checksum="84F928FB8BC5D593" modified="2008-01-15" version="1">MGILGILLVRLIVSFRPDTTIKFFLLYTLLSCKRPDWAVCGFKRFLFCHQSSLIIACGNVVLEESMNLMQIHGQFAALQAQRGRIAASRAPERIGYLQQFKRAIEQARPDIHAALQADFAKPAAEIEATEIQQVIEQINFAIKRLETWMQPKRVKTPTMLTGSKSWIQYEPRGVVLILAPWNYPLSLALMPLIGAVAAGNCAIVRPSERMPHTAQVVANIIATAFKPEHVTSVVGDVDTAEALLDLPFDHIFFTGSPRIGQYVMQRAAEHFSSVTLELGGKSPAIVDRSADLKRAAQAIVWGKFVNAGQTCVAPDHVWVQREQAQALTQLIIKQIERNYGKGDYTRLQSPDLANVIDANATARLRGLVNNSVAQGALVALGGQSTDHPARFAPTVLTNVKPSMAIMQEEIFGPILPILVYDQIDEVIMATRASGKPLTMAIFAENQAIINWLLREIPAGSSMINGVLLNVVNPNLPFGGVGQSGIGNYHGFYSFKTFSHERAVFQLGGLNLVNLFQPPYRSVSKRLAAWSRRIMSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZT8</accession>
    <name>A9AZT8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4510"/>
    <dbReference type="EnsemblBacteria" id="ABX07142">
        <property type="protein sequence ID" value="ABX07142"/>
        <property type="gene ID" value="Haur_4510"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4510"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1282426_0_0_0"/>
    <dbReference type="OMA" id="AFCHYIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4565-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="204" mass="22931" checksum="820BFA0E0D33E843" modified="2008-01-15" version="1">MIRPAIMDDLAPMLQLQALAFADKFSSAFGKRGIQRGVAALHQSHQMQGPSSLQGMYVMLAGSELVGTITLRTIEMRPDDVGLVEQAFLRELGAWGAFRAVHALSQIDHRIGRDEGFISDVAVAESYRRRGIAQAMMRHSMTLARELGKKRLGLYVSASNHSARALYRNLGFSEGQVRRSWWNALFLGERRWIYMSYNLRETSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZW6</accession>
    <name>A9AZW6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4539</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4539"/>
    <dbReference type="REBASE" id="16539">
        <property type="entry name" value="M.HauORF4539P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07170">
        <property type="protein sequence ID" value="ABX07170"/>
        <property type="gene ID" value="Haur_4539"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4539"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_0_0_0"/>
    <dbReference type="OMA" id="MNRHGFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4594-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="30869" checksum="3CCCA17D5FE11A87" modified="2008-01-15" version="1">MLTQALPLLNPPLKWAGGKRWLIPRLSDFWQNYQDYTLVEPFVGGLAIALGLQPQQALLNDINPHVINFYHWLQHGLVIDFELHNDQTYYYRYRDQFNQLIRAGAEQTAEAAGLFYYLNRTGYNGLCRFNQRGLFNVPFGRYKRIRYCYDFSHYAETLRQWRFQRGHFIEMQIPAQALIYADPPYDVPFRAYSQQGFNWSEQVQLAEWLAQHPGPVLASNQATQRILDLYRNLGFSIEILPAPRRIACNGDRQPALEMLAFKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B088</accession>
    <name>A9B088_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2559"/>
    <dbReference type="EnsemblBacteria" id="ABX05197">
        <property type="protein sequence ID" value="ABX05197"/>
        <property type="gene ID" value="Haur_2559"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2559"/>
    <dbReference type="HOGENOM" id="CLU_2219500_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2587-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="106" mass="12169" checksum="1BD0D50954CA5B1B" modified="2008-01-15" version="1">MIILGTRGNAVDTLKTAWHVCPSCQMNVPFNVQLIYRYFHLYFIFGVITSHQYVETCPNCLRRQIVPKEALPLEIRQGRYANITHQFGMAALAVFIIVMILINAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G9</accession>
    <name>A9B0G9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4556"/>
    <dbReference type="EnsemblBacteria" id="ABX07187">
        <property type="protein sequence ID" value="ABX07187"/>
        <property type="gene ID" value="Haur_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4556"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143569_0_0_0"/>
    <dbReference type="OMA" id="ILELWVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4611-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="15309" checksum="C5C08DFFC5D76307" modified="2008-01-15" version="1">MILYRPVGLEELTLIAQAGYRSFPAQLAEPPIAYPILNLEYASHVAESVKTKDAEAGYAGFVAEFEISEQYARQFAVKSVGIRRRHRELLVPIEEFHNFNTRILGHIKVIASFYGKQFRGMVNPVTALPTFISPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I4</accession>
    <name>A9B0I4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="11" type="ordered locus">Haur_4571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5 9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4571"/>
    <dbReference type="MEROPS" id="C44.001"/>
    <dbReference type="EnsemblBacteria" id="ABX07202">
        <property type="protein sequence ID" value="ABX07202"/>
        <property type="gene ID" value="Haur_4571"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4571"/>
    <dbReference type="eggNOG" id="COG0034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_3_1_0"/>
    <dbReference type="OMA" id="ENAQPTF"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GATASE_TYPE_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="10"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
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        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="355"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
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        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
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        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
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    </evidence>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX07202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="468" mass="51151" checksum="93FB803E83D6872E" modified="2008-01-15" version="1">MFSDSPHEECGVFGIYAPSEDVARITFFSLYALQHRGQESAGIAVSDGKTINTHKEMGLVSQIFDERSLRHLKGHIAIGHTRYSTTGSSQVINAQPFTMHTLLGPLAVGHNGNLTNAASLRRQLMERGVGLMTSSDSEVATMLLAGLEGNTWSQRIDAFTNCVEGAYCLTVLTRDALYAVRDPWGLRPLCLGRFGDAGWVVASESCAFDTIGAEFIREIDPGEVLQIDRDGPRTIAKHPAQQQAFCLFEYIYFSRPDSYLQGQLIHEVRMRLGHELAREAPAEADIVIGVPDSALPAALGFSQASGIPYGDGLIKNRYIGRTFIQPDQRLRQQGVALKLNPLPNVLNGKRVILIDDTIVRGTTSGPIIKLLRKAGATEVHMRVSAPPIRHPCFMGVDMATQPELIAFNKTEAEICETIGADSLAYLSMDGLIRATRRDANGFCGACFSGKYPFPIHEAGKEIFELTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L1</accession>
    <name>A9B0L1_HERA2</name>
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        <recommendedName>
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    <reference evidence="3" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
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            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14546" checksum="7070F19040FD2A46" modified="2008-01-15" version="1">MQDDQMVLRELVTTWIQATEAGEVSKILALLDDDVIFLVAGQAPLRGKAAFVAASAGLSQFEIKINFEIQEIKLNGKWATCWNQLRVQIQPPHGKPPIVRAGDSFSLWQKHAHGWLLLRDANMLQTLKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0W2</accession>
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        <submittedName>
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    <organism evidence="1 2">
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    <reference evidence="2" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="gene ID" value="Haur_1184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1184"/>
    <dbReference type="HOGENOM" id="CLU_2069881_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1206-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="13127" checksum="30111F0A7E03119A" modified="2008-01-15" version="1">MLRWTPDSNYLLALTCDPRTPWIRTNAVVYENSPTCDAASPIQHQRRGLVFRMADQQQLTEIVLPAHTGSIKLISPNLLGIIAYVNQEAFLIVCDITTGQQTVPLALGKVVPVIVYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B109</accession>
    <name>A9B109_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
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    </protein>
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        <name evidence="2" type="ordered locus">Haur_2649</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
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                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2649"/>
    <dbReference type="EnsemblBacteria" id="ABX05287">
        <property type="protein sequence ID" value="ABX05287"/>
        <property type="gene ID" value="Haur_2649"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2649"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_2_0_0"/>
    <dbReference type="OMA" id="GVSTTWY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2679-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
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    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="303" mass="34803" checksum="A0AD61AE4469D88A" modified="2008-01-15" version="1">MLPSHGFASKTWKYPMTKTPSLVPTKPNQIQRRRLLTDFLRARRARISPESVGLPNGQRRRTPGLRREEVALLAGVSVSWYTWFEQGREIQVSSAVLDSLVRVLQLDGYEREHLYVLARDSVNPLPWLCHEIDSGTQLMLDMLDPAPAYVISPCCTVVAWNQAAQLVFGDWQAKSMRERNLLWMTFSQPGARLFFADWVGETQRVLAFFRANSTKYIGHPILQELINDLMAISPEFCQLWAQHDVGGITIERKELRHWDLGSLVFHPKVLQIHNSDQQQLVVYLPLDEAQTREKLEQALTTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B171</accession>
    <name>A9B171_HERA2</name>
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        <submittedName>
            <fullName evidence="4">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ordered locus">Haur_2711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2711"/>
    <dbReference type="EnsemblBacteria" id="ABX05349">
        <property type="protein sequence ID" value="ABX05349"/>
        <property type="gene ID" value="Haur_2711"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2711"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1254500_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2742-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="27"/>
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    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="97"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="23683" checksum="8EC459D537005408" modified="2008-01-15" version="1">MASSLRGVGLLLIGIVIGMIIGVWWLAPRLNGTIIRFESATNPIASPSVPTITPNQAPMPSATSPASPSNSASPTPSATIQATASLTSSGDLKLDLLAAVNRERQQTNCEALVFDSRLQSIAQAHADDMAQHEKIDHVGSDGRSYSQRLEAVGYQFIRRGENISAWFATPIKVVAQWMDEPVDGPHRANITNCAYRHVGIGLAYVGDHPYWVLDMAEPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B0</accession>
    <name>A9B1B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="3 4">
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        <lineage>
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            <taxon>Chloroflexia</taxon>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4666"/>
    <dbReference type="EnsemblBacteria" id="ABX07297">
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        <property type="gene ID" value="Haur_4666"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4666"/>
    <dbReference type="HOGENOM" id="CLU_1684160_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4723-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="156" mass="17452" checksum="179859A42A37BF79" modified="2008-01-15" version="1">MKVSLNRRWFPLLGAFAAYIAWDLVDHQVLTPRSPVWLCYLIDWGVAGMAGWSIFILLERQYQHKKPLIDASTINLPPAVFAQLTQAAQGLQGEIHELQQAIGNSINEEGIQQQRSLRQALVASYRAQAILEEVSGIVDKPQVAPPPVEQLITQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1M0</accession>
    <name>A9B1M0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1257"/>
    <dbReference type="EnsemblBacteria" id="ABX03905">
        <property type="protein sequence ID" value="ABX03905"/>
        <property type="gene ID" value="Haur_1257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1257"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1029631_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1279-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="30535" checksum="62F8BE6E348D93F6" modified="2008-01-15" version="1">MASSSEARLAQFGELEPLWNKLQDSVRWPMIPPLANRDAPKGMQLRAILGAEASEIGLVQELFATIFPHLAHYEPFLAMYAEPFSRSHPATLDHLWLIEQHGKPVGVRMFSYLYRRNFGHGAFIGIDQRARGTGIGRWLVQATHQQLALDALYSGNEAVLGYSAEVTRVEDAQHELERQEREARLRFHLNNGAVLLPVEYIEPPVIKNSDDQAARQLTIASQPMHLVFYPSQPSPLNVATMRTIVEAIYHDVYYLESDNPFVQHALASLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W3</accession>
    <name>A9B1W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2767"/>
    <dbReference type="EnsemblBacteria" id="ABX05405">
        <property type="protein sequence ID" value="ABX05405"/>
        <property type="gene ID" value="Haur_2767"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2767"/>
    <dbReference type="HOGENOM" id="CLU_1376513_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2798-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="22606" checksum="80F504DAE237740E" modified="2008-01-15" version="1">MDMVDFVQTLVDDPSRLASFKQNPQGFLQQLGLGQKLAKADPIQEVTTVMTLRSVGTVAQTETQAYQDVPVTVSSYMNVFIEAADKSKDYNVTCWLLNHSYMIEDDSGNPYFDLHVCYVDPNDPDDVPQVFYIRSKNQIEQPTYNCANIPIELHIPANNYILVGRTRPVHTKLTNFVYHRQKDDQPPLFEIAFDEQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W5</accession>
    <name>A9B1W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2769</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2769"/>
    <dbReference type="EnsemblBacteria" id="ABX05407">
        <property type="protein sequence ID" value="ABX05407"/>
        <property type="gene ID" value="Haur_2769"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2769"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2800-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="23396" checksum="6660BB3D106E354F" modified="2008-01-15" version="1">MNSEVRNQNHHSETVALQLVEQICRGEHAAIWELYSLYHTELSQQCLVWMHGNPHDADEALSRLVLKAWESLPRHAYKITNAKAWLMRMAYNICIDIHRQQQRELKRLQPLDSLLGNDDSMPHSATPSPETALLKREVYETINQALQALSPRLNSTFSLWLYNDMSCDAIAQHQGISLANVYKRLQQARDMLQPQLRPSTVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B203</accession>
    <name>A9B203_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cys/Met metabolism pyridoxal-phosphate-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2807"/>
    <dbReference type="EnsemblBacteria" id="ABX05445">
        <property type="protein sequence ID" value="ABX05445"/>
        <property type="gene ID" value="Haur_2807"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2807"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_2_0"/>
    <dbReference type="OMA" id="PTVMEFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2838-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="373" mass="39180" checksum="5042F8D0E887308A" modified="2008-01-15" version="1">MGQDSASIKPESWLVSAGRGSQPGDPLNVPLVPASNFIIGSGREYSRDDGTPTWEALEAVVGGLEGGKALAFASGMAAIAAVFDQLAVGSQVALPDDCYQGVAGLAAAGQQRGRWSVQRVAVDDTEAWVRACADADLIWLESPSNPLLTVADLELICAAPRKPSAIVVVDNTFATPLNQQPLAFGATVAIQSATKFIGGHSDLLAGVATTNDAALWHALKKSRELTGATPGTLEAYLAVRGARTLAVRLQRAQQTAMLLAERLEAHPQIMRVRYPGLRSHPTHAVAQRVLKGFGTIISFDVLGGAVAADHVCQQVKLIHHATSLGAVESTMERRAAIPGQEHLPPALLRLSVGIEDAADLWHDLESAIAAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B234</accession>
    <name>A9B234_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ordered locus">Haur_4753</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4753"/>
    <dbReference type="EnsemblBacteria" id="ABX07384">
        <property type="protein sequence ID" value="ABX07384"/>
        <property type="gene ID" value="Haur_4753"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4753"/>
    <dbReference type="eggNOG" id="COG0817">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091257_3_1_0"/>
    <dbReference type="OMA" id="AICHIWR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX07384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="17959" checksum="58AD88C80514AD9A" modified="2008-01-15" version="1">MRIIGIDPGTAIMGWGIIDADGSDLTMVAYGAFTTPAKQPLPDRLVSIYNDLAHVLEHYRPSVAAVEELFFAKNVTTAMAVSHARGVALLALRQAKLPIFEYKPLSVKQAVVGYGNADKQQMQHLVQMTLNLDHIPKPDDAADALAVAMCHAYAAPYLNRIQEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B283</accession>
    <name>A9B283_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4802"/>
    <dbReference type="EnsemblBacteria" id="ABX07433">
        <property type="protein sequence ID" value="ABX07433"/>
        <property type="gene ID" value="Haur_4802"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4802"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_232511_0_0_0"/>
    <dbReference type="OMA" id="TATHEHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4861-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731807" evidence="3">
        <location>
            <begin position="27"/>
            <end position="2017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1940"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1967"/>
            <end position="1992"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="4">
        <location>
            <begin position="70"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2017" mass="219778" checksum="5A70F1E7C69E04B9" modified="2008-01-15" version="1">MFTFTKRVPMTLSSRLKRTVSGALLAAVTASTIPASPIAAQSRDTNPNTPPATPDVPPVASVRERTTPSLALNLRADQAFVSVGQTLGLTINLANVGDIPGTNILIRLPVPANTTPLTTDQLVADGSAWEWSIDALAARTSQTMRVQVRVNATTDATLLTTASLSATKLEQPVRSRSGTLIVAAGKARTITASRGSTATSLRTADNAIEVSIAKPTADTTLTLTPNVTDVPSNSKRGLPPFRITSTAKSGDMLLNLRYTDEQLRALGISASDLTLMAYDETTKTWKSVETTLDLQNRRVGARVAVGGNYQLTDGSSPSEAFLPSLQGWQTSLYTGAATSSYPIDVPAGPGGIKPDIALSYNSSSSDGKGGQRILSQAGWVGRDWSLEMGSVSANKVADGRTYYSLTFNGMAFDVTRGAALVGSPVEANLSHWTWTPVNETFAKVTAFELGDSTASRGGSRYGTPLKRYGWRVWSKDGTKYEFVEDAWWGWDTCEIDGAASMETYQWSLSSITDVNNNVITYNYSRDSQQRSTCNGIVGMVDREVWPTSVTWGANSGTGAIDRYKVDFNSSARTNDLDFDWAGNQLGDSNGAPRKTRQLDTINVSSKPNSAWELIRQYSLGYDYSTYADTTVNIDSDSERLTLKSIQRVGKSGSTTLPIDPNTAIALPATTFTYGTSPGTTQYYPDGAWNRLTQVNNGQGGTITFAYENIGQSINKTLYANYRRVSSKTLNDGRGNNYTTNYSYTNPALNTLGSALDSNDSSGQVYANSAVLYYNKYRNNTDMSSWLVHKARTEFRGHAKVTERDPNGNETDHYFYQGDANCTPAVYGSQMETDACFINIRNNEILKGKEYRTVQRQGSTSTMLRESGNYYIIEFYGFSVSPFAGLWRSFDYTNESFSVNYDPAPAGGPTATVNRTKYYYDPASQGGVQYGNVTKIEELDISGAVYRSTSNTYAPNTSSAYIVDRLVTQIIRDGQNRLLALTENRYDGAVTTQAVGTRGLLTLTRKYSNVPLATSTTGLTLVSSDTSFGYDAYGNQTTVTTYAQAGTRLFNGTTTTFSAPGNGATSSTVTSTYDSIFHAFSTSVSQPTGNTNSLVLNESAGYDYRMGTLTSVTDANGNVTNAEYDSFGRMVALIKPGDTSALPTVKAHYVDSAIPFRYWTETREASGLGGVQINSQFYDGLGRKIQTKQESMDGSQNIVVDTKYDGMNKVTHESQPRYVNETSGSFWIYTAIPGTGVNWTTKTYDSLGRLLTLTTPDGAKTTKRYWQYNNLSVVDTIDPNRYRTQHRSDEFGRLLQVQELSGNCTTWAFFSDFSCAGNYTNAWASYSLTTYAYSPLDLLITSTDANNNITSMTYDSLGRKLTMSDPDMGAWSYGYDVDGNLLSQIDAKNQTLSFEYDLLNRLTAKKQGSTTIASYSYDQFDAAHSNGKGQLTSMTDASGSSNWGYTARSEINKIAQTVDGTTYNTLNSYRADGQQVTTTYPTGEILTYGYDAAGRQTSLASSLGEIFQVNVNYDALGQKTSETLNNGLQTQYSYDPLSKRLTSTVTADIATLQERFRRDFTYDLAGNVRTISSQDTLNANEIMRYSYDHRDRVTNACAVSSTSSSVCIGGATFNQSYGYDAIGNITNKAGLSYSYTNGKPHAVSSVGGQSYTYDNNGNMLSGGGRSYTWNIENQPTQISTSTVTETYKYDGNNARIKKTTTTGGTVKSVLYIGSVEYWSDGKVISNYGVAARTTTGNPTTSNRGSVIYLHTDHLGSVGAITNGSGTVIEAERYDPWGATRSGNLTSTEFGYTGQRKDDGTGLLFYNARYYDAAIARFVSADSIVPGKEDSKGGSTKTLGYDDELAHRPLTVDFHEKKFALDYSKELRFTATKGFHFQLDEEALKDEKHQWGPQNAQTLNRYSYVVNNPLRFVDPSGHWSVSCWDHMRQCRFIFTPEETKEIANLILMGASSAGAIGAFLAAAKMGGPYGVYIALAVAAILFTGATVLGAAAFLGGHLEIYAMYDLRGMPIVTIPYIWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F7</accession>
    <name>A9B2F7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1357"/>
    <dbReference type="EnsemblBacteria" id="ABX04002">
        <property type="protein sequence ID" value="ABX04002"/>
        <property type="gene ID" value="Haur_1357"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1357"/>
    <dbReference type="HOGENOM" id="CLU_2301984_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1378-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="11696" checksum="D9F0447B9E36D7D5" modified="2008-01-15" version="1">MAIEENQGGQRYWRTSDHYADGCIKNNRIKIKITTGCLTVRIRLLERYTNPPVTVGVFDYQTRCAMLNKPFQSFGDPILPGTRYWLEMSYKPHDLLIVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2I0</accession>
    <name>A9B2I0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1380"/>
    <dbReference type="EnsemblBacteria" id="ABX04025">
        <property type="protein sequence ID" value="ABX04025"/>
        <property type="gene ID" value="Haur_1380"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1380"/>
    <dbReference type="eggNOG" id="ENOG502ZTFI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1141342_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1401-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="26245" checksum="9A512E29CA061DA1" modified="2008-01-15" version="1">MVRFFRSIKLFAADNGGGGSGSGGGGNPAPANPPANPPANPPASGGGNQPDIAGQIANLIARQGSPDAALMLLMQENYQYRDQNRQLRERVPDGAVVLSGDDVQRWRDYQALGQLDELRTRLTEREQAQTELTNLRTQATIRTVAEAMQWKSSVLERLAGNVTFITKTEGDKTTITVKDGDVETPLDAYADKHWGEFMPALKTDTAPAGRGTGFVRQGAGNPKNDDPITTHNQRMGYSLPKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N3</accession>
    <name>A9B2N3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2846"/>
    <dbReference type="EnsemblBacteria" id="ABX05484">
        <property type="protein sequence ID" value="ABX05484"/>
        <property type="gene ID" value="Haur_2846"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2846"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_1_0"/>
    <dbReference type="OMA" id="WLDPFFL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2877-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734507" evidence="4">
        <location>
            <begin position="24"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36798" checksum="5A378DA109578947" modified="2008-01-15" version="1">MRRWWIISFLSLFILASCGAEQAAPTTQGQTAKLNVVSTVSPITNIIYNIAGDKISLTGIVPEGVNSHTFEPVPSDAKTLAEADLIFINGLNLEEPTHKLAEANKQPSAEIILLGEQTITPEQYVYDFSFPKEAGSPNPHLWTHPLHGLRYAEIVRDALVRRDPSNAEYYNANYASFKTRIEAFDLAVKKTIESIPAENRKLLTYHDSWAYFAPHYGMTVIGAIQPADFAEPSAKDVADLITQIREQKVPAIFGSEVFPSPVLEQIGRETGVKYIDSLRDDDLPGEVGAANHSYLGLLTEDLRIMAENLGGDPSLIANFDTSNIPGSDSSVVQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P6</accession>
    <name>A9B2P6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2859"/>
    <dbReference type="EnsemblBacteria" id="ABX05497">
        <property type="protein sequence ID" value="ABX05497"/>
        <property type="gene ID" value="Haur_2859"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2859"/>
    <dbReference type="HOGENOM" id="CLU_2000766_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2890-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13047" checksum="138E3C5E8E1A03D3" modified="2008-01-15" version="1">MSQPPRFGRIPPNTAQLVAGLAQTVAGQVVTALPNHAGHATRAAATEIILGIVLRDWRENENTSGLLPDDVADLRSFVQLAATLAGNDLENQGAPVFRAVLTGLMEDWLANWNAPGDPGAPGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V2</accession>
    <name>A9B2V2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3379"/>
    <dbReference type="EnsemblBacteria" id="ABX06015">
        <property type="protein sequence ID" value="ABX06015"/>
        <property type="gene ID" value="Haur_3379"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3379"/>
    <dbReference type="eggNOG" id="COG1672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_764553_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3416-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="33"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="39635" checksum="BD6C53486A273517" modified="2008-01-15" version="1">MTQPYFSTTPIHDPRDFVGREREIVQINEALAAGRSCAVIGPQGSGKTSLLHHIGQAVAMVLDEPPQVVFLSLARVNEARDLYSPMLRALRANGDDELSLTQAFHEATTPPMLLLLDDLESAGMGWIGVVRSALRGWVNEGFLQIVAASSQPLDQIAADWQSTLSQITLAPMPEREVRSLITTLTQSTNLNPDPTTISQVIKLAGGYPAAIKLALELWAHSQATTQFDWQQMFREQQQAAYAGSSAAGYSTAIESEALPTKVKQHPVQPSKPAAKPAEPQRPRSYKADDPSEFLIMLILLSLAVLIGYLVGSWLGWFVAGLIMLIWIGLAHAMVRWRGNGALSHIYVRATRWLPVVGRFAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X8</accession>
    <name>A9B2X8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3405"/>
    <dbReference type="EnsemblBacteria" id="ABX06041">
        <property type="protein sequence ID" value="ABX06041"/>
        <property type="gene ID" value="Haur_3405"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3405"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016513_1_0_0"/>
    <dbReference type="OMA" id="GNVQCLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3442-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="1 3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AidB_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="5">
        <location>
            <begin position="172"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="4">
        <location>
            <begin position="281"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="556" mass="61584" checksum="E59AAD820DD0303D" modified="2008-01-15" version="1">MPPFNQPAPQLGNQYSDDRLLQLYLRRRLPADVLSQIKPALQTIGDLAGNELYQLQLADRLNEPQLTQWDAWGERIDQIVLTPLWQRAEQIAASYGLIATAYEQTFHEYSRTCQFALAYLFHPSSDVYSCPLAMTDGAARTLLQAGNQALIERAIPHLISRDPDQFWTSGQWMTESTGGSDVGLSETIARQAEDGTWRLYGRKWFSSATTSQMALTLARPEGNPAGGRGLALFYVETRDQRGRLTQIEVNRLKDKLGTRKVPTAELNLLGTPAIPVQGLRDGVRAIVPMLQITRTWNSVSAVGFMRRGMALAQDYAQKRWAFGSLLNQKPLHVDTLAGLQAEYAGAFLLTFYLIELLGLDETGRSTPQQRQLLRLLTSIAKLTTARQAVNHTSEIIESFGGAGYVEDTGLPSLLRDAQVLSIWEGTTNVLALDSLRALSEDPGIWPVLREQVNLWLSNAHDPSLSQAIVVVQTALDRCEQWLAESSNDRSVAEMGARRWALTLGRALELALLIEHAQAALIAPNDRWLAAAARRFSCSAVNLIATIDANDNQILLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B325</accession>
    <name>A9B325_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4858"/>
    <dbReference type="EnsemblBacteria" id="ABX07488">
        <property type="protein sequence ID" value="ABX07488"/>
        <property type="gene ID" value="Haur_4858"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4858"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4918-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="167"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="32264" checksum="346F5FB75F82C263" modified="2008-01-15" version="1">MSVEHALADFLEANLGRFAKHTGELLRQIPNSPYPKLSDAELIPRMQKPFVATISALRGDLQALIDFSRQSIKPVVDNPNASSDIVAQIGEAIYSTLKVAARECFADDELNYALALAAAAEVTFISNKNSYQAFVDIREARIREREETLQQMTSELDQANAALRELAAPIAPIHDNILVLPLVGSIDTNRAQMLTEDLLEQIVARQSDIVIMDITGVPIVDTNIANYLVQTTKAVSLLGAQVILVGISAEVAQTIVGLEIDLRQLSVRANLQDGIEYALEQVGLGIRPLQEQRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A9</accession>
    <name>A9B3A9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1428"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH81">
        <property type="family name" value="Glycoside Hydrolase Family 81"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04072">
        <property type="protein sequence ID" value="ABX04072"/>
        <property type="gene ID" value="Haur_1428"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1428"/>
    <dbReference type="eggNOG" id="COG5498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005482_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1450-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="PTHR31983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732408" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="826"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1139" mass="122183" checksum="B42775939F8F4578" modified="2008-01-15" version="1">MNTQHLPNRSRRLPWLAGTLLTLLTSSLFFSPTQPVANADQAGLGSYTTTLPAGAKVPDDFNGNPVSPKRTANVTGAMPTNDWWSSLGWQRFPGNPYSENMTALPLIVKAKATGLGVTFPTIPAISTGSPNYIGEFHYNASEDLNLGLVGLNSPDAKVDGYSDWTVTAYWNGGGTLRATFGHGMPFVYLTKSGGDALISAAAPPSVWTGAGTNALGITVNGHHYGIFAPTGTTWSQSGNNFQSNLAGKDYYSVAVLPDNSVATFNFFKSRAYAFVTNTTASWSYDQASATLNTTFSATTVAKEGSNTNTVLGLYRHHAINSSTALTNYSYTTARGQIRLRDGNSFTTAMRFNGVLPTLPDAGDYNRTTLNNHLNDVAFEASHFGGADTYYTGKALLRLANLIPIAEQLGNTNARNALITAVRNRLQEWFTASANDTNGQFYYNSNWGTVIGYPASFGSDTELNDHHFHYGYYIYAAAILAQYDPNWALDSNWGSMVKLLINDAANISTATDPRFPRLRTFDIYEGHSWASGHAGFGAGNNHESSSEAMMFNSAVLLWGANTGNTQLRDLGIFMYTHETHAIEQYWFNVDNAVFPAGFTANNNHPAVGMVWGDGGSYATWFSANPEMIHGINFLPFHGGSLYLGRNPAYVNKNYSQMRNNIGGAERYWLDVIWQFQAFGDAATAATKFDTVAYTPEEGETKAHTYHWIRNLKQLGSIDTSITANTPTYAVFNKNGVRTYVAWNPTANPLTVTFSNGVVLNSIPARSMARSTGTTPPPTATPVNPTATPVLPTATPVNPTATPVNPTATPVLPTATPVAGCSAVSLDANSYYRVTARHSGKALDVADVSSADGANVHQWGYVGGLNQQWRFESVGSNYFKVTARHSGKALDVAGGTTATGNGVNIHQWPYGNTTNQQWCLRDVGSGYYAIIARHSGKALDVADASTADGGNVHQWDYVGATNQQWQLTKIDAGGNTLHVIDGAAQNVAGTLSLSAGAGANTDSIPSAGGANRDGTPTNALVYTISGLTRTYNSQATQFKLFVDSNTAVGNGVQARISYDWTGDGSYDRTETYNYFPTDPVAGFEQYSQTAGLKSSSGAWANLSNGRVRIEIWNAIGNGTASVRTSATSDQGQQSTITLPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L3</accession>
    <name>A9B3L3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2947"/>
    <dbReference type="EnsemblBacteria" id="ABX05585">
        <property type="protein sequence ID" value="ABX05585"/>
        <property type="gene ID" value="Haur_2947"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2947"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136818_0_0_0"/>
    <dbReference type="OMA" id="AWFEGRY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2979-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="18194" checksum="50CF26196519B1C7" modified="2008-01-15" version="1">MPAFQHCHWCGAAFGAVQGFPRVCSACGNSTYRNPIPVSVILLPVERGLLTVRRAIEPRKGQLALPGGFVNVDESWQAAGVREVFEETNIQLDPHSIRDWWTRSTPDGMILIFGLAQPIRRTDVPNDFDRSETEALVVIDAPQVLAFPLHNEAMQAYFERLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P5</accession>
    <name>A9B3P5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2979"/>
    <dbReference type="EnsemblBacteria" id="ABX05617">
        <property type="protein sequence ID" value="ABX05617"/>
        <property type="gene ID" value="Haur_2979"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2979"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_806025_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3011-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735238" evidence="2">
        <location>
            <begin position="22"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="36072" checksum="FF0049F37F3B1A8E" modified="2008-01-15" version="1">MKRWLGILLIGLLGACQQQPAAAPSQAQIMPQVWIDAPLAGSALELGEIQVLAHGYHPMGLSTIELSVNGQVVATQQPTMRGSQFGYANLKWQPSQAAAYRLAVRAQSSQGQWSDPASAEVAVGQINSLRIAALPSATSVPSATTTPTTTPTATPTSSPTFTATPTRPIPSNTTRPAPTTVRPSNTPVRSTNTPVLPTPTDTPAPPKPTDTPVPPTATDTPVPSTPTDTPAPILPPIIGEPVASARAFAEQTACGMPDQITISVSVDNFPAGDVSLYYHAGPSRWQSTVMQGGGGNWSRTLFAKREMSGQRFGAFEYYILAQGSDGQSSKSQVYGGIEYLPCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y5</accession>
    <name>A9B3Y5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3485"/>
    <dbReference type="EnsemblBacteria" id="ABX06121">
        <property type="protein sequence ID" value="ABX06121"/>
        <property type="gene ID" value="Haur_3485"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3485"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_369108_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3522-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="754" mass="82691" checksum="5C1F49DECDD4DFA9" modified="2008-01-15" version="1">MNNSAHPQFNHQPMGMYAQQQFGEYQVRHKIGAGGMAEVYQADHPSFQTVALKLLNPLAINDPDMLQRFFQEANTVSQLHHPHIVAIYETAQTWYAPIQQWIPFIAMQYIDGGTLTERLQRQPKQDLAATLDMGRQIGSALDYAHGKHFIHRDIKPSNILFRGNGEAVLADFGIALARNQARITRTGGFVGTIAYTAPEVFDGITPDARADIYALGLILYEALAGNHPYWHETDSHEGVTIRKIQHTPLPPLREFAQFVSPGIADVITRAVMRDPDERFASMADFLEALEKARFPRSNSRANVPVPSHATLMQAPSRPNMGFGNSATNERHIKTVIQPEFKQPARTMPNAQPIGAVNSNVNQPLPASPSASPTWYGPAKPPAWQKLFDDKRWQVAAGVVVLGLIFWLGSTFFGNNSANADGDTPSTSVAMASTVPEPLATATVSVQAIETSTPTVDPLETKRLEYALGQEAYDRQDWPLAAQAFNRVWELEPTYLELESIGSATYFNWALGALNSPEAVAISQQYLAEAFRFDPNHALAKRLNNLLNSYQAGQQALSDGKTEASIEQLRQTLEQINSAQEFNGLRSELGVIEKLYQAYLLEARTAVEARDLAAAREAYRQAIELKDQDVNLDVSEAQAGLRAISPTPTPVPTARPQPTVARTPERLYFQKYAENAVDPTCFAVHVRGANTGGWFVTVDGLGNRGNLDGAGNTNVCGLIASQQVTFTVYNGSGQAVLGGSGIPTRGGDLMIGYWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B402</accession>
    <name>A9B402_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="9" type="ordered locus">Haur_3502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3502"/>
    <dbReference type="EnsemblBacteria" id="ABX06138">
        <property type="protein sequence ID" value="ABX06138"/>
        <property type="gene ID" value="Haur_3502"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3502"/>
    <dbReference type="eggNOG" id="COG0206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024865_0_1_0"/>
    <dbReference type="OMA" id="GNPSIGQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="13"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="207"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="21"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="389" mass="41340" checksum="7297D1D52A35546D" modified="2008-01-15" version="1">MDFNSNLIENFAQIKVIGVGGGGSNAVDRMVESGLQGVEFITVNTDAQALIHSPATIRVRIGDKLTRGLGSGGNPVIGQKAAEETHDELHDVLRGSDMVFITAGMGGGTGTGASPVIASIAQEIGALTVGVVTRPFLFEGNHRRKVAESGIDQLKPSVDALIVVPNDRLLQIASKNTKMNEAFRMADDVLRQGIQGISDLITSRGLINLDFADVKTIMSQQGTALMAIGHGIGDNRMIDAANMAISSPLLEISIDGAKGVLFNVTGGEDLGLLEVNEAAEIISKAADPDANIIFGARIDPNLPADEVKITIIATGFDQARPQGNNRSRSYPSAQSQPTSQPTSYQQPTQQPVRPAPQPQQPQRPTPPTSFGSNDDLDIPPFLRNRERRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B435</accession>
    <name>RS11_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsK</name>
        <name type="ordered locus">Haur_4938</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B435"/>
    <dbReference type="SMR" id="A9B435"/>
    <dbReference type="STRING" id="316274.Haur_4938"/>
    <dbReference type="EnsemblBacteria" id="ABX07568">
        <property type="protein sequence ID" value="ABX07568"/>
        <property type="gene ID" value="Haur_4938"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4938"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_0"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141102" description="30S ribosomal protein S11">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="137" mass="14631" checksum="58A7FA38EFAC3931" modified="2008-01-15" version="1">MAKQAKAGAARRPQRGRRRERKNVPRGQAHVQATFNNTIVTITDPAGNVVCWSSAGASGFKGSRKSTPYAAQVTAEQAARKAMDNGMRVVEVYVKGPGAGRESAVRALQATGLSVIAITDVTPIPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D1</accession>
    <name>A9B4D1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0036"/>
    <dbReference type="EnsemblBacteria" id="ABX02688">
        <property type="protein sequence ID" value="ABX02688"/>
        <property type="gene ID" value="Haur_0036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0036"/>
    <dbReference type="eggNOG" id="COG4636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076312_6_0_0"/>
    <dbReference type="OMA" id="YEEAPCA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-36-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="192" mass="21844" checksum="A7ABE775E2F6616E" modified="2008-01-15" version="1">MDGECMSAESISPMTIEEYLAGERTSPAKHEFLNGQVYALAGASRNHNLIVANLIAELHSQLKQRSCTVFPSDLRIKISATGLYTYPDVSVVHGETWFDDSHQDTLLNPTLIIEVLSPSTEHYDRGGKFQHYRQIPSLREYLLVAQDPYHIEHYSRQAANQWLLSEIDDPQVVLELRSIQCRLTVQEVYAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D9</accession>
    <name>A9B4D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase with TPR repeats</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0044"/>
    <dbReference type="EnsemblBacteria" id="ABX02696">
        <property type="protein sequence ID" value="ABX02696"/>
        <property type="gene ID" value="Haur_0044"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0044"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_4_0_0"/>
    <dbReference type="OMA" id="DIYQFAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-44-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="71"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="305"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1360" mass="152062" checksum="CB2CECEA9E7A7826" modified="2008-01-15" version="1">MSIQPPSSEFASLLRQVQQAEVMPTQTQLDDVYRQLDQRIQQLQRYVPDPIVQRLKHGELPIPYGERWLGSLLFADLSGFTALSESLTRLGKEGAEQVTSIINRLFNQLVADIEAHGGALIKFGGDAVTAFFDQTKLGEQHALYAAHAAQAMQTSMATLGKIQIRAGQFNLTLRIGVHSGEAFAALLGDQQHAELMLTGIAVNLVARAQELARPGEVVCSKETMRLLGLPTDPMNPFTALTTALEHPPYQSTSQAPSIPQTITLADVQALASIYAGIQRLLPQRMSEEQLLSNAASRTGEIRLVTIVFAHIAPFSTIVELCNDASATQLLNHYYQRMQQIVNHYGGVVNKLDMAADGDKLLAIFGAPIANENDTELAVRTGLDMQSAMNEINALIQQHDPRLPLLDQQIGINQGHVFAGIVGSETRREYTVMGDPVNTAVRLMSVCRYGEVLASPTIKRLTSHAFAYETLPALPLKGKSQPIEPARVDRAYNVRRETMRADLVGRVQELEQLATISIQALQGQGQIINIFGEAGIGKSRLLEELLSRLSLASFDPNLNVPEFMPITIECQLYEQTTPFASASEVLRQVLRLSSSLNGERLVQVISQRVNRLVPELERFLPLLSDILHVSLDENELTQALAPEQRHDQTIELVVALMLATANTTPLVILWDDAHWIDASSRQLLERLAKHADQAAIALLIGSRTKGLSAMTWPEQTVHLELSELSMPESEALASAIIGHAPLPAALLERWRRSDERFFNPQGNPFFIEEMMRSLIQQGVIVETAAGWDLRGELDSLPTTIEGVITARLDRLDNRIRETVQVASVVGRRFELNILRGITNDDDLVNQMDRLTNADVVLPDHIAAELAYLFKHTLTRDVAYEGILYARRRELHRRVAARIQEVHRQNLVDVLPILARHYARAEDWHEAVRYYREAGIASQKRYYNAEACAHYRDALELLPNLSAFDRSLEQELTERLGYVMMQAGDYAEALPILAQAQIQLRQSSVYSSSREARILRHITTIYERRGEYEPAFEHLQQALNLLGESQSAERVRALLLGSGLHQRQGRYHETITWAEQALAIAEQLNAQPEQARAYLLIGGTHRVLGSREQAVGYLAKSIELYQAVNDISRLADAYNNAAINFSDLEQWEESIALYQAALNIKKTINDSYGQALVSLNLGELYRKTQQFDQALETFNQSLQLWNKLNSKLGAAVTQMNMGNTLFAQGQSATAESMLDRSRAIFDEIHVDSFLPELYRIYAELFYSRHNYAKALDYCDFALEQARQHSAKADEGLAQLTQSKILLALDHYDPALHAAEQALKLLQECDNQADVERCLEQLIALTQTNDPQRMADYQNQLDQLTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E4</accession>
    <name>A9B4E4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0049"/>
    <dbReference type="EnsemblBacteria" id="ABX02701">
        <property type="protein sequence ID" value="ABX02701"/>
        <property type="gene ID" value="Haur_0049"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0049"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_5_0"/>
    <dbReference type="OMA" id="WVKIRTY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-49-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="36"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="170"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="252" mass="27830" checksum="9D92DAD3D753EF94" modified="2008-01-15" version="1">MNPTITTITPSFGWRMLGDSPMLSDTELALLRDVELFDGLAPEQAAQISRRLVRRTFPAGTNLMSVEQPGEVVYIILNGTVKIHVEQADGTDVIIAMLGAGDTVGEMSLIDSAGRSATVVTQEESTLLWMNRTAFLEALQNAPVITLNLVRMLSSRLRLANEQIQALATLDVHGRVARQLLAFAQKYGHADETGTVQIPIRLTQSDLAGLVGASRERVNQVIGYFKQRRYLSVDQHYHISLHNLEALAKRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G5</accession>
    <name>A9B4G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0070"/>
    <dbReference type="EnsemblBacteria" id="ABX02722">
        <property type="protein sequence ID" value="ABX02722"/>
        <property type="gene ID" value="Haur_0070"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0070"/>
    <dbReference type="eggNOG" id="COG1956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_392685_0_0_0"/>
    <dbReference type="OMA" id="MTEMHEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-71-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="487"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="702" mass="77230" checksum="E0157DB557C89002" modified="2008-01-15" version="1">MTEMHEFSQQPLVLIVDDQSSNRSIVRRYVEAAGYLAAEAEHGVAALDFVRQTPPDAILLDIFMPGIDGIEVLKTIRAQRDHHYIPIIVVTAAAELAVRQQAYFEGADDFLLKPVDSATLRARLRAAIRLKHVLSRVEAERERFALIADITRDITQIESISGMLAHVVDVSTKALQADHGNLFLLHDVADVEILTTDDGVSHNLDRVKRVVKEGAAGYALRSRETVRITDVHEDVRWLQLDQSAASVRSALIVPIGDASGPLGVLAVYHSVVDHFSADDQALLELIAHQIIGPIRQAQMREQLARQTRQLQLVNNLAQSLSANLDLDSLYRSIEQELQQIMGPVAIAWYSYRNAIIDLAYTSQQHAFCMPNDQQSLHLLTELGTITRVYSCVLGTDTLVPITQQLLDAGYQGCAAVPLLHQARLLGVLIIAIKHRQITNEEVALLEMARPHFAVALANAQTVADQAARQTEQAELGYLRNMAQLAGQMAHHFNNLLAVILGNTQLAELDAIDEGQRELLAEVVKHVRGGKEMVQRIHLLKGASRISPAPFPIDLSDALPSLIDQALQIHRSVEHLQLEIQPNLHILLQERELLTLCTELLNNALESGSSHAGIVIKAYQTEHATVLAFRDAGRGIPVEALGDIWQPFWTTHGPQRLGLGLPICAAVMWRASGSISLIPNDPEPGITALLQFPLLPNEAANSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B586</accession>
    <name>A9B586_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3587</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3587"/>
    <dbReference type="EnsemblBacteria" id="ABX06223">
        <property type="protein sequence ID" value="ABX06223"/>
        <property type="gene ID" value="Haur_3587"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3587"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_5_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3626-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731896" evidence="4">
        <location>
            <begin position="27"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="138"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="599" mass="63002" checksum="BE66D635A9E77998" modified="2008-01-15" version="1">MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVERQFARFETSVAQLTKPQIAQLQAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQYPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQRIDNTTARYNQGSRFLIYKDMLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQASYSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGNTGPNPATIMAPANVPYIISVGAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSRVIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYYALSGTSMAAAEVSGIVALLLQDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMDLPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSYLTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M6</accession>
    <name>A9B5M6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1616"/>
    <dbReference type="EnsemblBacteria" id="ABX04259">
        <property type="protein sequence ID" value="ABX04259"/>
        <property type="gene ID" value="Haur_1616"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1616"/>
    <dbReference type="eggNOG" id="ENOG502ZP6F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1576339_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1640-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="19375" checksum="02B998C05E7EF8A8" modified="2008-01-15" version="1">MSMLDPYEIERIERSRKRATRLLMVVMSLATLFCGALFIYIISPPPREYSIGPVSQFPIGQTIQVSVKQLVASKTIVSRPEVSDDPLLVTRLSTDQWRVFLAWDSLSGCIVLYQQSDQTYRDQCSDRVYDERGLLISESRRLRLGELPVTIVGDQVQIRDELLPDPRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T6</accession>
    <name>A9B5T6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">greA</name>
        <name evidence="8" type="ordered locus">Haur_1676</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1676"/>
    <dbReference type="EnsemblBacteria" id="ABX04319">
        <property type="protein sequence ID" value="ABX04319"/>
        <property type="gene ID" value="Haur_1676"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1676"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_2_1_0"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="6">
        <location>
            <begin position="83"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17395" checksum="BFA0378677982357" modified="2008-01-15" version="1">MTDKPFYLTKEGRAKLEAEIEELETTGRMEVAERIRQAKELGDISESGEYEDAKNKQAFLEGRIREIRNILNNAQMIEEDGDNREVRLGSSVTIRYEDGEEEEWMIVGAAEASPRDGKISNESPIGSALMGKRARQKATASTPSGIMKMTVLKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U6</accession>
    <name>A9B5U6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3101"/>
    <dbReference type="EnsemblBacteria" id="ABX05739">
        <property type="protein sequence ID" value="ABX05739"/>
        <property type="gene ID" value="Haur_3101"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3101"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094953_0_0_0"/>
    <dbReference type="OMA" id="VVPHLYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3133-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="44"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="24169" checksum="2E2DAC7FFB0FF1F1" modified="2008-01-15" version="1">MFDAFKRKFDATPEGMEERVPPGQYVTQKFPVLHYGETPIYKELEQTWDLRVFGEIEAQKTFSYNEFRALPTVTIENIDIHCVTRWSKLATTWTGVRFRDFLTHIPALKPSAQFVLAHSEGGYTANMPLEIMFDDDVLLAYLYEGEELAPDHGFPLRLFVPKKYFWKSAKWLRGIEFMSADRLGFWERYGYHNNADPWQEERHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B620</accession>
    <name>A9B620_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3176"/>
    <dbReference type="EnsemblBacteria" id="ABX05813">
        <property type="protein sequence ID" value="ABX05813"/>
        <property type="gene ID" value="Haur_3176"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3176"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_771351_0_0_0"/>
    <dbReference type="OMA" id="PQMLECA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3211-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="123"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="39376" checksum="0BF194B9C74E5397" modified="2008-01-15" version="1">MLRFGRALIEFGRGLVGWLGLFNLLSALANLPNLGWLAQRRRDGLLGAALAVWGWRGGRWRWLSVWLAVPIQLALASLRSLWHNPLRQFMAGSTSCEPIQIMLDSGEHVPGLWYATSHTSTAILYLHGAGNDKTRYATRAIAQLQQAGFSVLAIDLAGQGENPRTLDVPDSNTDVAAAVAWLRQHAEHVVVVAVSLGGCIGARAIADGVAVDGLVIIGSPVALDLKSNHYIRSELRALLRPQFWQYPDRMTLYQLWQQWQAPPMRIAMGFNQLFPTLNLADSLSRIRAPILLVYGQRDRIAPYQAVLSNLATIPDVTLQLMPDHSHLTLPMETFPLTAVTTWIHERIESSEGAIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B638</accession>
    <name>A9B638_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent RecD-like DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recD2</name>
        <name evidence="3" type="ordered locus">Haur_3613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecD family. RecD-like subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3613"/>
    <dbReference type="EnsemblBacteria" id="ABX06249">
        <property type="protein sequence ID" value="ABX06249"/>
        <property type="gene ID" value="Haur_3613"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3613"/>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007524_0_3_0"/>
    <dbReference type="OMA" id="SHPQYGR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01488">
        <property type="entry name" value="RecD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006345">
        <property type="entry name" value="DNA_helicase_RecD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029493">
        <property type="entry name" value="RecD-like_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041451">
        <property type="entry name" value="RecD-like_SH13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14490">
        <property type="entry name" value="HHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18335">
        <property type="entry name" value="SH3_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01448">
        <property type="entry name" value="recD_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="334"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="345"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="719" mass="79221" checksum="60EF6EE61F4F01DF" modified="2008-01-15" version="1">MDQLTGNLERITYRSDETGYTVARLKAQGQRSVITIVGRLPDVQVGEQLQLEGQWIEHRTHGRQFEVASYQTARPTGNESIVRYLASGLLPGIGPVNAQRIADTFGEATLDVLDTMPERLREVKGLGTKKIAAIIVAWQEQRAIKALLELGQAVGLTTGLALRIFRHYGEQASQIVQHDPYRLALEIEGIGFPTADHIAQALGVARDAPSRVIAGLRYTLSMVANTEGHCALPQIELIAQTQTILELPHELIAEQLAVATESVLLVLDGDLVYLPAYYHAETELAHNLQRLQQLPSAIQLRFKQQSDAIIMRQLHNASFDLSQRQAEAVLAVLRSKVVLLTGGPGTGKTTTVRAILALLQQVGLRTILAAPTGRAARRLAETTNHPAATIHRTLEYSGGAGNDRWGRNEHAQLVADLVVIDETSMLDIVLAHHMVKALAPTTHLLLVGDPDQLPAVGPGAVLRDLLASNRITTVHLDTIFRQAADSQIITNAHAINQGQLPSVNQGDFYWFPRSNPAECGAMIVDLLTTRIPRQFPQFDPLRDIQVLAATHRGAAGVLELNSQLQAALNPPNTTRQEATIAGTLFREGDRVIQTRNNYDLDVSNGDLGLIQTIDLEERTVSVYFDDTRNVVYQWNEFDEVALAYAISVHKAQGSEYPVVIVPMLRYYNVLLNRPLLYTAITRARQLVILTGDWQAVEFAIAQRRSGQRITGLSQRFGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C1</accession>
    <name>A9B6C1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0172"/>
    <dbReference type="EnsemblBacteria" id="ABX02824">
        <property type="protein sequence ID" value="ABX02824"/>
        <property type="gene ID" value="Haur_0172"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0172"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_0_0"/>
    <dbReference type="OMA" id="PVEDTYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-175-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="26704" checksum="E57DAF29A4618C64" modified="2008-01-15" version="1">MLRFPVVCFDVGFTLLDERVDAHDLIGEVLQELGLQVEPNLIRDARKATNRWYHQRYHSLDNNDWSSDATIRTLWLEFYQHLFDQIDPSLDHARLGDRLIAHYEQPENWVPFNDVRETLDSLHAKGIRIGIVSDWASSLRPILTYNKLLPYFDFAVISADAGYAKPMTDLYQLAIKRSGVAADQIIHIGDSYYADVLGARAVGMQAALIDRHKRIPKADCPILHDLRDLLPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6F9</accession>
    <name>A9B6F9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0210"/>
    <dbReference type="EnsemblBacteria" id="ABX02862">
        <property type="protein sequence ID" value="ABX02862"/>
        <property type="gene ID" value="Haur_0210"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0210"/>
    <dbReference type="eggNOG" id="COG0391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044041_0_0_0"/>
    <dbReference type="OMA" id="RSKACKI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-213-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="48272" checksum="D0B6E661C5F67CED" modified="2008-01-15" version="1">MKQSVPASARKLLDSRWLKVGIGVKRWLALMLFGLMFSALGLAFGLRELYTTVELPAIFYYLTLQFWPRTIRMIILCLVGISATGFAFRHLNRVLLSAALPRNTAPIDLAETLIGRSRTRHGPKVVALGGGHGLSTLLSGLKQYTDNITAIVAVADDGGSSGRIRQEFGILPPGDIRRCLAALAEAEPLMTRLFEHRFQAGSLEGHTFGNLFITALAEVTGSFGEGVREANRVLAVRGQIVPATLDDVVLWAELENGEHISGESRIAKSGQRIKRVYLQPHGALAVRAAIKAIEEADLIIVGPGSLYTSLLSSLMISEINQAMREAVQAVRVYVCNVATEPGETDHFGVRDHLQALVEHVGPDVFDVALANSDDRQNHRFAPEWQGRTTIVPLDQTQDLPIRVRTANVINPANPLRHDPVRLARELMRVLEKERQMGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G3</accession>
    <name>A9B6G3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic component of the Tol biopolymer transport system-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0214"/>
    <dbReference type="EnsemblBacteria" id="ABX02866">
        <property type="protein sequence ID" value="ABX02866"/>
        <property type="gene ID" value="Haur_0214"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0214"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_838804_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-217-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735490" evidence="1">
        <location>
            <begin position="20"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="36905" checksum="5D9B2959BF30AB77" modified="2008-01-15" version="1">MKQLFMFTAFLLIASGCTMQTPMTQIPTTPITPTQLAVPAGIYSGLAWLDQGLVLQARTANNPVENLYWIDQQGNLGESLSIPLEQAFVMTSYYFPQRLPNGKLGLRRYNWNPNLETGISEREFGVWQFDPTTNDLTPLLQPALPQDLSQHLRFSLAPDMQRAMLSDGGYLQSRLFWWSAEAGHQPLDAGVAICQYFAWSPDGTTIAYAGSPHAADSMATLGGVRSTLYLMDSDGGNRREIGTNIRNVSGLQWSPDGQWLVVLGYFDGFDNQVWLVNPTKAEWHQLTTTVGNYQWPAWSPDGKQIAVIWRKPADLGPSDYVMTLDVSAFMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L1</accession>
    <name>A9B6L1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02914">
        <property type="protein sequence ID" value="ABX02914"/>
        <property type="gene ID" value="Haur_0262"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0262"/>
    <dbReference type="eggNOG" id="ENOG502ZCPN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1426211_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-265-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="18290" checksum="B9970778590E02F7" modified="2008-01-15" version="1">MADTSDEKKARLDAIRAANAAKKAAAGEEPAPAPAAPVVAATTEAPASAAVGANMSDDKKARLEAIRAAKKAAASDAPVAPVAVAATPTPAAAPVVAATPAAAPAAPVAPKPAAPASNGNDLITANSIISLTMLGRLKRIVAGVAFCVLIGLGLATVTGEYLLGGGFGALIGVVGGLMVGDWPAVKTTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q5</accession>
    <name>A9B6Q5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1721"/>
    <dbReference type="EnsemblBacteria" id="ABX04364">
        <property type="protein sequence ID" value="ABX04364"/>
        <property type="gene ID" value="Haur_1721"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1721"/>
    <dbReference type="eggNOG" id="COG1178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021838_0_0_0"/>
    <dbReference type="OMA" id="QAFWRVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1748-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="60"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="333"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="530" mass="57430" checksum="B6BA27010CD320A3" modified="2008-01-15" version="1">MVFKHLRFRSGRWSALFLTISAGLIALIMVLPVGYLLLRTSEAGSTAWAQLQRPSTLRVFTGSALLAITVTAGSLLIGLPLAWLTTRTNLPGARIWLTLIMLPMAIPSYIGAWAIIAVLGPRGLVQQWLEPLGVERLPEVYGFWGAAGALILFGYPYIVLNVRVALRKLDPALEEAARSLGQRSSHIFWRITLPQLRPALAAGSLLVILYALSDFGAVSLLRYNSFTRAIYLQYRASFDRTGAAVLSLLLVGLACGLLTAEALSRGRARYYRSSAGVSRQPKLVGLGIWRWPALIFCAIVVLFAVVLPIVAIVAWLIIGLRAGQTWNLQLTDLANSLLAASLAALVTIVLAFPVVFLAVRYPSRLTSLIERATYVGYALPGIVVALALVFWGANYLPWAYQTLGLLILAYAVRFLPQAIGSLRTSLLQINPRLEEAGRSLGQPAWRVVLSVTLPLLRPGIISGAALVFLSTLKELPATLLLGPTGFHTLATDIWNNTAELRFSQTALPALLLMVAAGASLALLLANERKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S0</accession>
    <name>A9B6S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1736"/>
    <dbReference type="EnsemblBacteria" id="ABX04379">
        <property type="protein sequence ID" value="ABX04379"/>
        <property type="gene ID" value="Haur_1736"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1736"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_1_0"/>
    <dbReference type="OMA" id="VFIWIVR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1763-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="37357" checksum="E596F50ABC36332D" modified="2008-01-15" version="1">MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLLGMETGDPQHVLIVRTLRLPRMLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGLVAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKGGDSPMRLVLIGVGLSAVGSAVTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLGEDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVPTAGMLGALLLVASDWIGRTIAAPNEIPCGLVTAVIGVPFFLAMLYQHARTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B704</accession>
    <name>A9B704_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="13" type="ordered locus">Haur_3235</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3235"/>
    <dbReference type="EnsemblBacteria" id="ABX05872">
        <property type="protein sequence ID" value="ABX05872"/>
        <property type="gene ID" value="Haur_3235"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3235"/>
    <dbReference type="eggNOG" id="COG1159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038009_4_1_0"/>
    <dbReference type="OMA" id="EWEMEIA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3270-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="12">
        <location>
            <begin position="196"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="384"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="230"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="251"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="313"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="340"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="251"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="313"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX05872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="489" mass="54949" checksum="9E4D91E322F265AF" modified="2008-01-15" version="1">MLELTFDADARALYAYFTDINEGDDASQLEIPGVFLLDAAGQIVGVRLQLASAPKKSFLQYAQGFEELSYDEAAQQLTLSFGQHVVAATEELPYDAIVDLDRKGRALGLEVQAMIEFGLNERLEVLNPWLVAFDEESDDEFEADEDADDEQAAAKLEVKPEPTAEDEDEARPAVHQPIKLNPNLPKPLLPTDQEVHSGFVALVGKPNVGKSTLLNAYLGQKVSIVSPKPQTTRVPVRGILNGPDAQIIFVDTPGIHKPRHKLGNFMVDVAKRAVPNADVICFMVDITVPPNRMDREIAQMVLLSRKPHILVLNKVDATDEADKHLQEYRDLAPWEMEVAVSARDKLGMETLLAEIVQRLPVGHRLYPEDQLSDVSERSLVAEMIREKVMLNTEEEIPHSIAVEVEEWEDRGKVVYIRANISVEKDSQKGIIIGAGGSMLRKIGATSRFEIERSLGRQIYLDLWIKVRENWRQKPNELRWLGYDVKFFRD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-22" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B745</accession>
    <name>RS7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsG</name>
        <name type="ordered locus">Haur_3276</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B745"/>
    <dbReference type="SMR" id="A9B745"/>
    <dbReference type="STRING" id="316274.Haur_3276"/>
    <dbReference type="EnsemblBacteria" id="ABX05913">
        <property type="protein sequence ID" value="ABX05913"/>
        <property type="gene ID" value="Haur_3276"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3276"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_0"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000344296" description="30S ribosomal protein S7">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <sequence length="157" mass="17983" checksum="DA1232586365A0DE" modified="2008-01-15" version="1">MPRRRKIAKRIVPGDPIHNSIHVQMLINKVMMHGKKSVAENIVYRALDVAAQRLNREPVDLFEQVLRNSSPTIEVRPKRVGGSTYQVPVEVKSDRRIALAIRWLLTAARGRSGKPMHERLALELVDAFNNTGATVKRREEVHRMAEANRAFSHYARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B1</accession>
    <name>A9B7B1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
            <ecNumber evidence="8">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3758"/>
    <dbReference type="EnsemblBacteria" id="ABX06394">
        <property type="protein sequence ID" value="ABX06394"/>
        <property type="gene ID" value="Haur_3758"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3758"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_1_0"/>
    <dbReference type="OMA" id="WVWMLIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3800-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37799" checksum="1B635E4B1C9A3A15" modified="2008-01-15" version="1">MDLNSIWFVLVAVLFIGFFILEGFDYGVGMLLPWLGRDDQERRVVINTIGPFWDGNEVWVLTAGGAIFAAFPEWYATLFSGFYLALFLMLCALIVRAVAFEYRSKVADPRWRTTWDWVIFFGSAVPALLWGVALGNLLRGVPIDADKQFVGNFFDLLNPYALLVGLTTLSMFLLHGALFLNLKTTDELRERSLKLAQRIGPVATVLILAFIVATYSATDTFSRLGVNPGIIPVSALLTLLGAGWFVHTKQTGWAFIMTCLTIGLSVITIFMALFPRVMISSLDPNWSLTIYNASSSPYTLKIMSFVALIFVPIVLGYQAWTYWVFRQRVSTKSKLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C4</accession>
    <name>A9B7C4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3771"/>
    <dbReference type="EnsemblBacteria" id="ABX06407">
        <property type="protein sequence ID" value="ABX06407"/>
        <property type="gene ID" value="Haur_3771"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3771"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1003885_0_0_0"/>
    <dbReference type="OMA" id="AYINEQH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3813-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010838">
        <property type="entry name" value="DUF1444"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07285">
        <property type="entry name" value="DUF1444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="31931" checksum="46C997168D680E91" modified="2008-01-15" version="1">MEDRPLLDDDEFGDVVEERLEQLGGIEELSRDGMEIRFRWHGRAVVSELEHFYNAYRRSPEQLESILQSLEAAVRSFAPDRGQELWDELEDRVYPMIKPASMLLEVAERNLPQLVYRPFLADLIVCYVIDEPESVAYINEEHLKTWGVLETTIYTKAVDNLRIKTLKPGMAQVMGEGNQMLFIYSTSDGYDAARILLTDVLSEWADLLPGNLVLGIPNRDFLIGFSDANPEILQRIAMQIAQDAYKLDYGLSDQLWTIKQGQILIYEYDWSSSERKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K7</accession>
    <name>A9B7K7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0328"/>
    <dbReference type="EnsemblBacteria" id="ABX02980">
        <property type="protein sequence ID" value="ABX02980"/>
        <property type="gene ID" value="Haur_0328"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0328"/>
    <dbReference type="eggNOG" id="ENOG5033ZTC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_642172_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-331-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="427" mass="49895" checksum="91E34E50DF50FB6F" modified="2008-01-15" version="1">MARNIMLNHSIRLYGHFIQQQLPPSNYKEFSRWGIDEQNIYRSEYLQMSSLTQMCTMFTYLYHSAIADRQKWNILCESFGTMLIYQIYEVISDNISMGLGLAINPDYQQKNQLIRYFNTAMVESLDNGIIMLDHQRIKALSKNISLIEQHISLTRNQDLFDKYCAHKNIRLDTIEEPEIWVALYANIASCLDFINQIKQPSARTLIKNSVISRYTAINRLNNAEYTSINQLIQLQIDTMLVIPTLEYCINLWSEVYLDDQALRDDIAENPYLRQYITTATLLVRLLNDVGSILLQLSHQQIAQYFSQLLLESPPLKHEAWYDWFNRVASHPMFFRLHKDVVFNEVNILLYAIEPTMDPSTVIDQMIHNTQHAAQLYQATMALFEQQFGLLSQTSHYRIPLDIASRIVTFHQALYANDYTQPEGEYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L6</accession>
    <name>A9B7L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0337</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0337"/>
    <dbReference type="EnsemblBacteria" id="ABX02989">
        <property type="protein sequence ID" value="ABX02989"/>
        <property type="gene ID" value="Haur_0337"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0337"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="TMTERFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-340-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="40"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="359"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="414"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="628" mass="69497" checksum="65CF4D201FB9A6DC" modified="2008-01-15" version="1">MNGGGWRGFVRANEDEQPTISRMLLQRVWGYARPYRSGIIVVLITIFIGTLLDRITPLLVRHLIDVAIPERNLGRLNLVAVGLVAIPLIGGLLDILQRRHSSLVGEGIIFDLRRALYSHMQRMSLRFFTSTKSGELVSRLNNDVVGSQRAVTGTLITLITNVITVSITLFIMLTIEWRLTLLALLVLPLFMLPARRVGRIVRNLTRSQMQANGEMNGLMGETLNVSGALLVKIFGRRNDEVAKFSQHAGEVRDLGIRTALVMRSFFVMVGLVSAVGVTSVYWFGGYLAITSDNFSTGDIIALALYLPGLYGAISTLVNTRVELASSLVSFERVFEILDLPLEIVDAEQPQILQTIRGEVQFEHVWFRYQADEINSLSSRDGQETTVISPITTREWALSDIDFTAKPGQLVALVGPSGAGKTSLTYLLPRLYDPSRGRVLIDGIDVRELELDSLGQAIGMVTQETFLFHESLRANLRYAKPDATDAELEAACRAANIHDLIASLPNGYDTVVGERGYRFSGGEKQRIAIARVILKNPRILVLDEATSALDSRSEALIQAALQPLLKDRTSIVIAHRLSTILAADLILVVDQGRVLERGTHSELLAQAGLYAQLYQTQFKEREQALEQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N0</accession>
    <name>A9B7N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0352"/>
    <dbReference type="EnsemblBacteria" id="ABX03003">
        <property type="protein sequence ID" value="ABX03003"/>
        <property type="gene ID" value="Haur_0352"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0352"/>
    <dbReference type="eggNOG" id="COG1174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_7_2_0"/>
    <dbReference type="OMA" id="TAYVLQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-355-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="48"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="104"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="22"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="22779" checksum="7C2BE030E7CDB7EA" modified="2008-01-15" version="1">MNDIVDGLRYLLTERAEVWQLLGQHVTISLIALLIASLIALPLGVLVVRVGWLAGGVMAVLSVLYTIPSLAMLIMLIAVFGLSKTTVIVTLVIYAQVILVRNIVVGLKSIDRSVLEAARGLGMNAWQIWWQVELPLALPIMLAGLRIAAMMCIAISSIAAMIGVGGLGQLLFQGITFDRADMIWAGTISIASLALVCYGLLALVEQRFSPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S5</accession>
    <name>A9B7S5_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </organism>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1810"/>
    <dbReference type="EnsemblBacteria" id="ABX04453">
        <property type="protein sequence ID" value="ABX04453"/>
        <property type="gene ID" value="Haur_1810"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1810"/>
    <dbReference type="eggNOG" id="COG3553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127482_1_0_0"/>
    <dbReference type="OMA" id="KLCKHYA"/>
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    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014543">
        <property type="entry name" value="UCP028291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09981">
        <property type="entry name" value="DUF2218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028291">
        <property type="entry name" value="UCP028291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="10930" checksum="FA736F1AC73A5E72" modified="2008-01-15" version="1">MQSQATIPTALGSSYIKKLCKHYAHKIKVEYDDQQGTAYFAMGTCAMQAEAERLIFVIDAETSEAIGAIQHIMDEHFEQFAFREKLKIEWQAVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U5</accession>
    <name>A9B7U5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1830</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1830"/>
    <dbReference type="EnsemblBacteria" id="ABX04473">
        <property type="protein sequence ID" value="ABX04473"/>
        <property type="gene ID" value="Haur_1830"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1830"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="IPITRAH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1858-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="55"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="359"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="393"/>
            <end position="400"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="596" mass="66115" checksum="D6A880D66C484D22" modified="2008-01-15" version="1">MPMTNQSLAARRSSAAAKSTAQNPMRLLLTLYREDWGKLALASLIYIVKHSPVWIMPLITADIINIIASQGQIGLGRLWFDGFLLLIVLLQNIPTQYVYIRLLSRAIRRMESKLRSMLAQQLQLISIGFYNQRSSGVLQAKVLRDVEIIEQLTRNVFQSFPAAILNLLAAIIVVAFRSPWFLVFFVATVPLAAIVLRTTRNPIQSSNSAFRHQVERLAARLSEMIQLIPITRAHAAEEEEMRKLDRRLVQFQHAGLRLDAVNSLFGAASWVSFNLFNGLCLVVAAWACYTQFLPLAVGDVVLMTSYFSILTGAVMELANLAPQISKGLESVQSVSEILDNDDIEDNEGKQRLNQVAGHFQFNNVHFSYPDTQRSSLYDLTLEVQPGETIAFVGPSGSGKSTLLNLVIGFLQPSAGNILLDGHDLQTLDLRSYRRHISVVSQETLLFDGSVRDNICYGLNDVSEATIEQALRDANALEFVLDMPDGLDTIIGERGTRLSGGQRQRLAIARALIRNPRVLILDEATSALDSISEGLIQEALERLMQGRTTFVVAHRLSTVRNADRIVVIEHGQIVEVGSHQTLIAQHGAYAQLQALQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B838</accession>
    <name>A9B838_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3335"/>
    <dbReference type="EnsemblBacteria" id="ABX05971">
        <property type="protein sequence ID" value="ABX05971"/>
        <property type="gene ID" value="Haur_3335"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3335"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_10_1_0"/>
    <dbReference type="OMA" id="KWEGILI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3372-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="9">
        <location>
            <begin position="398"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="10">
        <location>
            <begin position="529"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="620" mass="65429" checksum="9DC04EE284AAE32A" modified="2008-01-15" version="1">MDAHSLLLMAGMVICFGIATFVLAERIGIPSIVLLLLVGVLVGPEVFGLVDPSALGVGLRVLIPLFVAIIVFEGGLVLDINDLRRLSYPLQMLMSVGALVTWGSATLVAHFVAGLSWPLATLFGALMSVTGPTVITPLMRCSNAKERLKVLLQAEGVLVDAVGAILAVVVLDVLLTSGTTISGAFDWAERLLIGSLIGLIGGIGLAYALRFIGSKLNAETTRLSALGGAIAIFIIAEAISHEAGIAAAAVSGIVVGNIDFPHEEEVVLFKGDLTMLAITIIFILLAARLKFADLAALGWWGVLAVVLMIVVVRPLCVFASTLGSTLTWRERAFIAAVCPRGVVAASVATFAAISLEEAGFAGGNLLIGLVFMTVIGTVVLQSFTTPLFARLLGVEPMTTLVIGANDLGQLFARQLHSQHHDVVVIDTDQQLIDRVRQHGISTITGDATDLQVLRKAGVERDKAVVALTPSDKLNLLVSQVVRSHFKVTTIVAQAENESTSSVLRDLGITVLNPLQASVDALTQLVQGPSAMSMLLSHQADQSIYEVEVSNPRVVGKPLKQLNLPNNVLIVAIRRAGNLFVPDGQTQLQAADQLTLIGTASTIQQADQQLREGASEAMYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B846</accession>
    <name>A9B846_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3343"/>
    <dbReference type="EnsemblBacteria" id="ABX05979">
        <property type="protein sequence ID" value="ABX05979"/>
        <property type="gene ID" value="Haur_3343"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3343"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_1_1_0"/>
    <dbReference type="OMA" id="DEYLFPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3380-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="244" mass="27027" checksum="22E080EB7D1100EF" modified="2008-01-15" version="1">MRVLVLADIHANLAALEAVLGAAGEVDSVWCLGDTVGYGPQPNECVALMRERQQAMLVGNHDLGCLGTIPLTNFNRDARIANEWNGLQLTEEHREFLLSLSPMQQVNDMVTLAHGSPRDPVWEYLLDTVGATYSFDHFSTPICFVGHTHQPVIFTADMLGDHCTATIPTDQLVLKLQPDKRYIINAGGVGQPRDGDARSGWAIYDDEQQTVSFHRTTYNIRRTQTLMLEHGLPNILAARLSFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B857</accession>
    <name>A9B857_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3354"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05990">
        <property type="protein sequence ID" value="ABX05990"/>
        <property type="gene ID" value="Haur_3354"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3354"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684919_0_0_0"/>
    <dbReference type="OMA" id="KPQPING"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3391-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="409" mass="45578" checksum="6E034CBC8480A03B" modified="2008-01-15" version="1">MRRVVFLITMGIERPSGQRYFNLAKELVRQGDQVRILALHPDLEQCQQRRFVQDGVEIWYVGQMHSRKRHGEVLPFSPLQLLAVLIRATLGMLWAILCSPAEIYHLGKPQPVNGLAAILGVLLGRGQRFWVDCDDDEVGSNRLTNQAQRMVFGFWQWLLPRLAQGVTVNTQALAARMLAARVANIVYVPNGVDLSLFQAPEPAVLAGLRTSLGLDGMQVIAYVGTIALHNHPINLLLEAFDQQLKHDPLIRLVLVGGGEDLGYVQTWIRDHGYHDRIFCLGHQDRRSIPMWMALANVTVDPVYDDMVAQARSPLKLFESLALGIPPVTGDVGDRRLVLNFAADRLIAPAGDALALAQTLQAVLATWSTTNRQACFERATDYAWSALALRWRAGYEESYANQALDSTSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B862</accession>
    <name>A9B862_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3359"/>
    <dbReference type="EnsemblBacteria" id="ABX05995">
        <property type="protein sequence ID" value="ABX05995"/>
        <property type="gene ID" value="Haur_3359"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3359"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062821_2_0_0"/>
    <dbReference type="OMA" id="DTDWYAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3396-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05711">
        <property type="entry name" value="TylF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="27592" checksum="E1703E4FE4AFE064" modified="2008-01-15" version="1">MGIKASLKYITSTLINAWQLSKLNRLQPKLVAAISHVQQQHLTYLEQQALLDLGAAVAQIEQQGVMGQMLELGCAAGGSAIVITSVKAKQRPFAIYDVFGMIPPPSERDGQDVHQRYEVISTGKSLGLGNRRYYGYEEALDQKVITAFAEAGYPIEEHQVSLVKGLYEDSLQINQPVALAHIDCDWYDSVMVCLERIVPHLAQGGILVIDDYASWSGCRQAVDDFFRDRQAEFRFEHKSRLHITRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B899</accession>
    <name>A9B899_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3816"/>
    <dbReference type="EnsemblBacteria" id="ABX06452">
        <property type="protein sequence ID" value="ABX06452"/>
        <property type="gene ID" value="Haur_3816"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3816"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_3_0"/>
    <dbReference type="OMA" id="TMLYWET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3858-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="5"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="20514" checksum="A214FEF13C4F1B1D" modified="2008-01-15" version="1">MGNLTFSLNITLDGCIDHQAGIADDETHAFFTQLMDESGAMLWGRITYEMMESAWPAVARGTTEAAQSLREWAIKLEAKPKYVVSSTRTDFPWTNSHLITGNLRTAVQQLKDTTPNGVLLGSGRLATELDRLDLINEYKFLIHPRIAGHGPTLYASGLSNARRLTLISAIPLRNGTVAMHYQRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D1</accession>
    <name>A9B8D1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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    <dbReference type="EnsemblBacteria" id="ABX06484">
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    <dbReference type="KEGG" id="hau:Haur_3848"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_347733_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3891-MON"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E4</accession>
    <name>A9B8E4_HERA2</name>
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        <submittedName>
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            <taxon>Herpetosiphonales</taxon>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX06497">
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        <property type="gene ID" value="Haur_3863"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3863"/>
    <dbReference type="HOGENOM" id="CLU_1093140_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3905-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
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            <end position="215"/>
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            <end position="127"/>
        </location>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="28447" checksum="94328C160B20E4B1" modified="2008-01-15" version="1">MTTDLLQAARQALQEHNYPLAQQHLIPLVRANPSNGEAWWHLAQTFDDPQKRQDCLDRAQRHGYSPPVAIAEPEIILPWEQADAWNSPMPMTNPSPSFAPPPPSSAVAANPRQPAPSAAHQLPTAPPYPTLKPADLRQIVSILKSPVSRDQQIQSVMGMFHCSAEHADTLLQGVAYHYPEQFKSPVKRNLYRISVEVASVLLGVILTLIATFLIFDPDRTNSLRWPVRLLLVGIFITLTASYRVFKLMYNTPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E7</accession>
    <name>A9B8E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase family 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3866</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX06500">
        <property type="protein sequence ID" value="ABX06500"/>
        <property type="gene ID" value="Haur_3866"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_021313_0_0_0"/>
    <dbReference type="OMA" id="RWWFPEE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3908-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019962">
        <property type="entry name" value="CHP03663"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41710">
        <property type="entry name" value="PTHR41710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03663">
        <property type="entry name" value="TIGR03663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="507"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="73"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="848" mass="95623" checksum="15848ED3B914D44E" modified="2008-01-15" version="1">MIATSSRQVAVPRTQRRRFTVEHLAYIGLGLLSVLMHVWALGGRSLHHDETIHAYYSWLLYRGDGYLHDPLTHGPFLYYWTALQYFLFGDNEFTARLAAATFGIALTLTPWLLRKNIGRGTALLMVGYLLISPVTLYVGRFIRHDIFAVTQEIICLIAIIRYISTRHVRWIYIFFASFALMFVTIETSYLFTLTLGSFIVLVTLWQVNRKLLILFGVYGLLAVACLKGIPDHRGLLVTANGNPAPVLDANGQEQWLPLPLVTESQALVVRNQGDDLFFDDTANGGFRQGYFSKLRETLFGISAAEVQSNPSRLYHQVKNQTLYGNNGVFMHMPITALTLLTLVFLIAVIVIIWFYKGKDQTQTMWKRAVSQAPERSLLPALDSLWSMHGALAVILGLVIYAAFFTSFGVHPVGVVSGIAGSLLYWVAQHDVERGGQPSHYYFVQLLVYEPLLLFAGFAGTLAGIGHLVLQIKRGAALTAQRMAPGLLAWWAAGSFALYSWAGEKMPWITLHVAVPLIFIAAWGIGRIFTWGFQPIQKAWLSSKIPTRRDEWLGLFGYLAVVGLVASYALMQLVRMIRIQPNIAPTGSPATPMFLVSMILIMLAITGFYSLFHGWRRALTGLTLALTIMWSAYSFRSAWRLNYQNGDIPVEMLVYVQSSPDVGRVMDDLRKISVAETGRMELPIMYDNEQIWKWYVREYTKAVGFSGSMNSPATAETAAILMIDSNWSTNEANVQGFLEGRFPLRWWFPESQFYRFAEVPELDANGQTMRDSSGEQVMKAAPYEQDSTIGRLIRDPFDAKTQNELWRYLLFRQPPGQLSSVDFKVYVRPRYAHVLGVQAQNVNGQSQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J7</accession>
    <name>A9B8J7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_5031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="8 9">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="9">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8 9">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07661">
        <property type="protein sequence ID" value="ABX07661"/>
        <property type="gene ID" value="Haur_5031"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5031"/>
    <dbReference type="HOGENOM" id="CLU_2273492_0_0_0"/>
    <dbReference type="OMA" id="NNRRNGI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5094-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0614">Plasmid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="102" mass="11360" checksum="967AFAAD077EDB79" modified="2008-01-15" version="1">MEQMLDAELTAHLGYEPYAPEGRNSGNTRDGSRPRRLRTSAGDHTIQVPRDRNSTFQPALLDPYQTSTNELEEKIIALYFKGVSACDIQQTLHELTLLGKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P6</accession>
    <name>A9B8P6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas2</name>
        <name evidence="11" type="ordered locus">Haur_5082</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="11 12">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="12">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11 12">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07710">
        <property type="protein sequence ID" value="ABX07710"/>
        <property type="gene ID" value="Haur_5082"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5082"/>
    <dbReference type="HOGENOM" id="CLU_161124_2_1_0"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0614">Plasmid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="104" mass="11915" checksum="9F7B6F2E98808173" modified="2008-01-15" version="1">MRTLLIYDIVDDRIRGKVADLCLDYALKRLQYSAFIGDIPRTLSEELWLKISKLVLNQEHSIEMIPICAKDWADHRSSSGKPKPIPIVADDDDGWGERSDDDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B936</accession>
    <name>A9B936_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07850">
        <property type="protein sequence ID" value="ABX07850"/>
        <property type="gene ID" value="Haur_5223"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5223"/>
    <dbReference type="HOGENOM" id="CLU_1813153_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5285-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="15907" checksum="59A37A9A43FC1724" modified="2008-01-15" version="1">MACGHSQGAFIPVYPSPAQPRPTLTPYQPMRQDTALIVDLPIAALQPTVYLTMDISQTLQFASSMRDIPLEWNMKFDPLVWDATAQGIPIVSDGVMQADPPATIRLVPQARGSTTMRIFLRYDPCQGCETVWRETHYEITIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B984</accession>
    <name>A9B984_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_5271</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="10 11">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10 11">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5271"/>
    <dbReference type="EnsemblBacteria" id="ABX07898">
        <property type="protein sequence ID" value="ABX07898"/>
        <property type="gene ID" value="Haur_5271"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5271"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="OMA" id="ASTWWQQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5333-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-0614">Plasmid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="792"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="953" mass="103151" checksum="D192A623592D5A98" modified="2008-01-15" version="1">MELPALIAVLVDAILIKCPQYDRASVTIALESVFAGHPTLLGGNSISMLLGQNNDYTNATITIGDVNAGNQVHVTVTLPQPIDPLPAALAALASIPLTDVPTPRSDLPQASRLPFESSPHFVGREAELNALAQAIGTAQPAVVMPAVATGLGGIGKTSLVTEFSYRYGVYFQGGVFWLNCADPDQVANQIAACAVGLKLDTTGMALDEQVQRVLHAWQSPMPRLLIFDNCEDPAILDQWKPTVGGCRVLVTARSDAWPTLTQIRLGLLSPVESRALLQRLCARLTDAEADAIAEDLGHLPLALHLAGSYLATYPHHTIGQYRKDLTIAHRSLKGRGALPSPTRHELDVEATFMLSFNQLDPNNALDALALGMLDGAAWCAPGVPIPCDLVLALVLAEAGDDGHPSRTTDRDDAVDALRRLQQLGLLNGTELVVLHRLLAQVVQSRLGSLDMLAEVESCLAWVTATVTASGNPQRLTPLIAHMRYVTLRALDRGDLVAIQLADQLGAFEQLHGAYAAAQIVYERALVICGSHLGMGHVITAGILHNLGVTLAHQGRYKEAQAWYEHALVITEQVVGADHPYTGGILSNLGVVLDHQGAYAEALPLIERSIAIRDRVLGADHPDTAMSLNNRGVVLEHQGRYREAQHCYEQAVAITTALVGDSHPTTAKYRSNIALMLERQGQYAAAARIHETVVAIIETVLGAEHPDTAMSLHNWAFALINQGQAAQAQTLMERAIGINERVHGREHRATALCIHHLGLALIHQERYAEAQPILEQAIGIYERVVGPRHPEIAAVISNLGGVLAHQGRYGDAEQCYERALAIREAVLGSEHPDTATTRNNLNSLITAKGYGLRAVLLNNCAVLFASQGCFKDAQYLFEQALALYEPLLRLHHSDTTTVIENMGCLLMLQDRSIEAVGLIERACMLYEQSIGRDHEMTNRLRVYGAELKESIQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU89</accession>
    <name>A9AU89_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Regulatory protein GntR HTH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0357</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0357"/>
    <dbReference type="EnsemblBacteria" id="ABX03008">
        <property type="protein sequence ID" value="ABX03008"/>
        <property type="gene ID" value="Haur_0357"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0357"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_0"/>
    <dbReference type="OMA" id="WETAGPN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-360-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019217">
        <property type="term" value="P:regulation of fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014178">
        <property type="entry name" value="FA-response_TF_FadR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028374">
        <property type="entry name" value="FadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43537:SF10">
        <property type="entry name" value="PTHR43537:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07840">
        <property type="entry name" value="FadR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="9">
        <location>
            <begin position="5"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26098" checksum="8C185AC5636640AB" modified="2008-01-15" version="1">MSELQRPASYCEQQLIKRIIGGSYAAGSSLPSERELAVQLGVTRPTLREAIQRLARDGWLVVQQGKPTMVCNIWHDGGLGVLRSLVQYSTELPAQIVPQLLAVRLDLAPSYTAMAIEHHAEAIAALLQTALPLADNAAAYAQFDWQLQHQLTIASTNPIYTLILNGFRGFYQMMALDYFELAQAREHSAAFYRTLLQAAQTRDADLARQASQFAMQQSIEVWQLLAANINNTQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB4</accession>
    <name>A9AUB4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0382"/>
    <dbReference type="EnsemblBacteria" id="ABX03033">
        <property type="protein sequence ID" value="ABX03033"/>
        <property type="gene ID" value="Haur_0382"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0382"/>
    <dbReference type="eggNOG" id="COG2852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1298370_0_0_0"/>
    <dbReference type="OMA" id="HPRANEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-385-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="24660" checksum="49DDBECB27392033" modified="2008-01-15" version="1">MPEANTPVLVAVLNNHADWQRIQHEHWYRVPLAHAPRRMAAGMLAWYQTKAFGDEGGQIRWYAPIEHVSQATRSQLIPEQPEHPRAHERYWRLEVGALQALPQPIMAQRFRRITFISTNWQQLIHAKQINDLWLGDSLLEQLSQQLISEGMNVVRRRLHDGNTPPQGTFVLIPLLNQIEVSIGEQRLRLDHDDLIWDFAGCLTNIRALQQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK0</accession>
    <name>A9AUK0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1884"/>
    <dbReference type="EnsemblBacteria" id="ABX04527">
        <property type="protein sequence ID" value="ABX04527"/>
        <property type="gene ID" value="Haur_1884"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1884"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_0"/>
    <dbReference type="OMA" id="RVAAYKY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1913-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="411"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="495" mass="54800" checksum="AD403F252511A665" modified="2008-01-15" version="1">MNIAQHLERACLCFPDKPALIFEQTTYSYAELNQIANRVANGLAQLGITKGERVALLLPNIPQFIFAYLGIIKLGAIAVSLNTQLQSAEVSFILNDSQATAIVVTPELAGQVQTDQLSHLRQLLVASPEATPNSLAYLIEHANPEYQAQTMERDDPAAIVYSSGTTGFPKGVTLSHSNVISNMHAKNLYCDMRPEDRLLLCVPLFHCFGQNAILNSAINACATLVLHRSFNYEQIIQSIARDQVTMFFGVPTIYVLLLNKAEPAALSSIRYFFSGAAIMPVEIARRWHATFKSFIHEGYGLTETSPFAAYNHRFRYKFGSIGMPIDTVEMRIVDVDTGANLAAEQVGEIIVRGPNVMLGYWNNPTATEQAIRNGWFHTGDLGKYDAEGYFYIVDRLKDMINVAGIKVYPAEVEQVIYQLPAVAEVAVYGIADEVTGERVMAKVVIKSGHQLSEREIFALCRKQIASFKIPSSIEFVESIPKNATGKVLKRLLRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK9</accession>
    <name>A9AUK9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear protein SET</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1893"/>
    <dbReference type="EnsemblBacteria" id="ABX04536">
        <property type="protein sequence ID" value="ABX04536"/>
        <property type="gene ID" value="Haur_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1893"/>
    <dbReference type="eggNOG" id="COG2940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2035239_0_0_0"/>
    <dbReference type="OMA" id="DRYAYPS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1922-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SSF82199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14726" checksum="EA80DA2A3562C941" modified="2008-01-15" version="1">MLLVASYLAPSTIHGIGVFAANFIPANTIIWEFTAAVDWRMTADEVAAFPEPYRSAFTAYIYVDDEGYYVLCGDNARYFNHSPTPNCDDAGAYTRTLRDIQAGEELTCDYFVFDQITRQHGLDVTSFVRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ7</accession>
    <name>A9AUQ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1941"/>
    <dbReference type="EnsemblBacteria" id="ABX04584">
        <property type="protein sequence ID" value="ABX04584"/>
        <property type="gene ID" value="Haur_1941"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1941"/>
    <dbReference type="HOGENOM" id="CLU_2342908_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1970-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="97" mass="10393" checksum="8885B414BFB192AF" modified="2008-01-15" version="1">MVAALHRRLVVLSSICMVSLNCSMIKRGMIGPNAILGGFMNLSATCECGTEYDLNYVEQAGGASFSYDACPDCGIQLDRETVAEAIHADPEAQAELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUZ4</accession>
    <name>A9AUZ4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ordered locus">Haur_3948</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3948"/>
    <dbReference type="EnsemblBacteria" id="ABX06582">
        <property type="protein sequence ID" value="ABX06582"/>
        <property type="gene ID" value="Haur_3948"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3948"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_0"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="289"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="463"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="614" mass="67219" checksum="2BB850E3D3EEE1CC" modified="2008-01-15" version="1">MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHAEPTAGHQGIGHTRWATHGAVTEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRFHSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAVVAMDQTQPDLILAARIGNAGAVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTVAWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCIYAVACGTAWHACLINKYFIETLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDTLAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGPEISVASTKVFTGMLMAGYLFALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWVNAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVEQVIARGGKVIALVNPSDELVRSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGADVDQPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF2</accession>
    <name>A9AVF2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04643">
        <property type="protein sequence ID" value="ABX04643"/>
        <property type="gene ID" value="Haur_2000"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2000"/>
    <dbReference type="HOGENOM" id="CLU_1608594_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2029-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="19253" checksum="13E391625D37AF8D" modified="2008-01-15" version="1">MEIKPLVIGLGTERRLVLHFVELDLREQRVLVSLTVKDHWLRVEDFRCWFARTTLETFAEQLEPWLRVRTTDAALISDFDYEEINNFSLKLQVLGGRGDIRVVYALDATEYELLVANGEFDFNLDFLWQFVTDVQQHAATLAQIWNDPAIRAAYPHVYPLSEPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH5</accession>
    <name>A9AVH5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2023"/>
    <dbReference type="EnsemblBacteria" id="ABX04666">
        <property type="protein sequence ID" value="ABX04666"/>
        <property type="gene ID" value="Haur_2023"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2023"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029016_4_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2052-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003806">
        <property type="entry name" value="ATP-grasp_PylC-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02655">
        <property type="entry name" value="ATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="113"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="45578" checksum="41F9B3A674D3C631" modified="2008-01-15" version="1">MKILVLNRQKPHLAPFGDWLGDLVPQARLFTAANRVQGFQGFAAIQPFENYEDSGLIEFEALRLHRQSPIERIVATSEVDILRAGRLRSYLGLPGQQADSALAFRNKVVMKQHLVNRTQLVNIPIFQAINEPFDIIQFIEQHGYPVIVKPDDGSGSLGAKMLANEDDLAQFLQQPLPRGLEIECFIQGDQYHVDGLLVDNEVCFCWPSQYLGNGLSFTQGWFTASQMLRPEHHLTQRLIAAAKEVLALLPTPPVTSFHLELFHTPGDELFFCEIASRTGGGMINGTIEQAFGINLNQLFIQGQAGMPIDTSRLRAITQPKKIVGWGLVPPQAGVFRGYRQAKPPQPWVLHFDWSIQAGTHSQPAQMSVDQVGGFIVDLTDAPNPEERLIEVWRWAEHQALWEPAGVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVJ6</accession>
    <name>A9AVJ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04687">
        <property type="protein sequence ID" value="ABX04687"/>
        <property type="gene ID" value="Haur_2044"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2044"/>
    <dbReference type="HOGENOM" id="CLU_1088918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2073-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="28947" checksum="DB191B5792E57680" modified="2008-01-15" version="1">MDKPYLIEQIGRAAFQRACTQARNAAPAMGTRTQSQSYHSPLPQWIDRMIWEQADGLTTAQRLRLSVSMYRDLPCYGVLLGLMCRYQGLDRVHQKLYWFEVRRMLSHGDPAWSGPIEYHLALDWFERNDDGATIWQTLRRAANPALLRSLLRSSGPAAWSLKMALYRELLADPAWHAAIYASVLASYGGVYGQIDRVEALTVLHHLILPHRDDAEWRSMLTVLGHGDRYTNGFGVKAFHAPQQDDEGSGDQAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM4</accession>
    <name>A9AVM4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ordered locus">Haur_3992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3992"/>
    <dbReference type="EnsemblBacteria" id="ABX06624">
        <property type="protein sequence ID" value="ABX06624"/>
        <property type="gene ID" value="Haur_3992"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3992"/>
    <dbReference type="eggNOG" id="COG0540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_2_0_0"/>
    <dbReference type="OMA" id="FPTEREY"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="161"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="318" mass="34815" checksum="3D3F66ABC7074042" modified="2008-01-15" version="1">MSSPTTTPRRRHVLDLDDWSADELRTLLTIATQMKDVLERPVKQVPTLRGKIVVNMFWEDSTRTRSSFELAAKALSANVLSLGAKDTSVKKGESLVDTVRTVQALGADYIVMRHGQSGSPYLVAQHFRGSVINGGDGRHAHPSQALLDLFTMHERLGELADKKVVIVGDILHSRVARSNLWALTTMGAKVVVCGPPTLIGPAKYWQSTWPNVEISHSLDQAAEGADVLMALRLQHERMEGGLLPSLREYSRRFGLNATRVASANSNVIVMHPGPMNEGVEIMPDVATGPHSVIETQITNGVAMRMALFYYLATGSEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF2</accession>
    <name>A9AWF2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4079"/>
    <dbReference type="EnsemblBacteria" id="ABX06711">
        <property type="protein sequence ID" value="ABX06711"/>
        <property type="gene ID" value="Haur_4079"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4079"/>
    <dbReference type="eggNOG" id="COG0287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055968_0_0_0"/>
    <dbReference type="OMA" id="MWRDICL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4123-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35753" checksum="4218E43125E0964F" modified="2008-01-15" version="1">MAYTVAILGTGLIGASLGLALGTADPESAPLGRCKVIGYDGSSQQLRIARGRLAIDAEAKTAAEAVKEADIVVLATPVQTLPALMREIAPHLRYKALVTDVCSTKASVLQWARELLPTTVSFVGGHPMAGREKNGAEAAELDLFKGAVYCLCPALNATAEATDLATAFVETIGAKPYYIDPEEHDIYVAGISHLPFLLATAQTEVVTRSPSWREMQMVAASGFRDITRLASGDPVMHRDICSTNRTALKHWVNESIRVLVEMRTALEDDQIDELQRMFEHAKTMRDQWLTLPQNQRPGEGDQLNDTDLGTSLGQRLFGNPSALLRGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWI6</accession>
    <name>A9AWI6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4113"/>
    <dbReference type="EnsemblBacteria" id="ABX06745">
        <property type="protein sequence ID" value="ABX06745"/>
        <property type="gene ID" value="Haur_4113"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4113"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="IIFIDIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4159-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13976" checksum="E61D3D263D919616" modified="2008-01-15" version="1">MGMIKILVADDEPDVLFMTSFSLRSLGGFEVIEAHNGAEAVELALQVTPELLVLDIKMPRMTGYEACRELRKYPQFASTPIILLSAKGQKTEIEEGWESGATEYMLKPYAPATLIGRVRELLSTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW7</accession>
    <name>A9AWW7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0720"/>
    <dbReference type="EnsemblBacteria" id="ABX03368">
        <property type="protein sequence ID" value="ABX03368"/>
        <property type="gene ID" value="Haur_0720"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0720"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="GYRFRQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-732-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
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    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
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            <end position="230"/>
        </location>
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    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
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            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="26694" checksum="9E6F4455F6F61D43" modified="2008-01-15" version="1">MPARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPGMTGFELSDRLRRYVEIPVIMLTSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLTKSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPIELRVLYLLLQTPTVAVATTTLLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW9</accession>
    <name>A9AWW9_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0722"/>
    <dbReference type="EnsemblBacteria" id="ABX03370">
        <property type="protein sequence ID" value="ABX03370"/>
        <property type="gene ID" value="Haur_0722"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0722"/>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_3_4_0"/>
    <dbReference type="OMA" id="PRMIVHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-734-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
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    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
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    <dbReference type="PANTHER" id="PTHR22617">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="15786" checksum="34173BE74F46CBAB" modified="2008-01-15" version="1">MSQVEDQLAQFVVFILDQERFALPVEQARGIERWRNPTRIPGTATAIMGIINQRGVLLTVVDMRVVLGMKPITPTRRSRFLLVHEQIDCAIAVDQVIDMLTLDVGLAEPTPHRGTVASRGLLPTPFGFATWLDLNALLGSING</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX22</accession>
    <name>A9AX22_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2190"/>
    <dbReference type="EnsemblBacteria" id="ABX04830">
        <property type="protein sequence ID" value="ABX04830"/>
        <property type="gene ID" value="Haur_2190"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2190"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051623_0_0_0"/>
    <dbReference type="OMA" id="LLVKHYF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2218-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="422" mass="46547" checksum="E52C1C0A685F3133" modified="2008-01-15" version="1">MRIVSLPARQSIQRLLGEHLKKRPGLWLFISMMLVNAGNYGFNVLVGRWLGPSAYAEINLMITLFLIATFITSGLQMSAARAIVGSNNQAILTMLRRVAWVCGGLSLLGLGLFAAFWQTLFHTASASPFIILGVGLACYYALGVERGIAQGCAHFGRLAWNFQIEMAVRLMGACVFVGLGMGVAGATIALSSSIVIAWLDSRRSYATVEQHRTNNSIQLQMMLPIIIHLLGQVLINNSDVLLVKAWFPAMIAGQYAALALIGRVVFFATATLGTILFPRVLRSTQHSEQQRLFWQSIMITVAIAGLITLLCKIIPQLILGWLFGEAYLPIADFLWLYAVATSCYAIANISITYQLAQDRSFGAWIALLAGSIQIGVMSWFNQSIHQILYSQVGVMLGLLLVLMLYEFYRARARQKFSKSRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX45</accession>
    <name>A9AX45_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2213"/>
    <dbReference type="EnsemblBacteria" id="ABX04853">
        <property type="protein sequence ID" value="ABX04853"/>
        <property type="gene ID" value="Haur_2213"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2213"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1989555_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2241-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="40"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="13610" checksum="562DF86ECA409902" modified="2008-01-15" version="1">MSEPFMPISVVLPEAGTTLIGDIRCKVSSAATNDQCTVLEVTLPPGQGAAMHQHEVEMEILVVQAGRCTVGDERNQWVLEVGGIAHFPQRTRHFFRNDHPETCVILITAIPGGLDRFFEALAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX49</accession>
    <name>A9AX49_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2217"/>
    <dbReference type="EnsemblBacteria" id="ABX04857">
        <property type="protein sequence ID" value="ABX04857"/>
        <property type="gene ID" value="Haur_2217"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2217"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591566_0_0_0"/>
    <dbReference type="OMA" id="FPHERMW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2245-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04843">
        <property type="entry name" value="Peptidases_S8_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034073">
        <property type="entry name" value="Subtilisin_DY-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="4">
        <location>
            <begin position="192"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="462" mass="49729" checksum="47D4219BDD9E2843" modified="2008-01-15" version="1">MLFPPTNQHGPLARCIVVKFHDQQAPLIYTDQNFQGYVVQPLFNSVDPDQLVGLVQQAQQTNPEYQAPNFLAFFAIDVEPDQDPFAIIEEINQWAELEYAYVESPPAPVPTDANPRRARQTYLNPPSSTGPTIGGIDAEAAWKVLEHAGKAITIVDIEKSWQLEHPDLLQHGSSPITILPSLLHCDMHDPACADHGTNVLGVLVAQNNTEGGVGIAHDAAAAVISPWQKPSNGTNQPSWNIANAIVAASNYLTTLELSGNLILLELQIYQDLAGGPYTNTPNQPGRLLPVELEPANFEAIRLASELGIIVIEAAGNGASDLATCWDTVGTYQIEPETARYRDSGAILVGAVYSRDPNKATRTASSNYGQRVNCFAWGNGVFTTNASGYSLSFGGTSAAAAIIAGAAILAQAIGEQLRQARFSPEELRRLLTHPDACTYSAQPQHDRVGVMPDLGRIIGLLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX62</accession>
    <name>A9AX62_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2230"/>
    <dbReference type="EnsemblBacteria" id="ABX04870">
        <property type="protein sequence ID" value="ABX04870"/>
        <property type="gene ID" value="Haur_2230"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2230"/>
    <dbReference type="eggNOG" id="ENOG502Z9AK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095955_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2258-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017576">
        <property type="entry name" value="CRISPR-assoc_prot_Csc1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03159">
        <property type="entry name" value="cas_Csc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="27927" checksum="BF04120AF66B2F0B" modified="2008-01-15" version="1">MAQIYRCRLVLLEPTFFSTREISNLYQTEAFIGHIALAYALGLAPSRYANDGKTIYYQQDLAALNQAGVYLTPATITSQARFSLGQFNAQAESYWFAMGNNAIITAPEGTWAERNGSSWYINDGVSTPKKVRVENRPQFGRIRALAIGTTAEFYAISQHELSLPSYLRLGKWMSKASLASQAVAISGESDGGVIPFLLAGADLSPDCRLLAFDVLHVPPTPLIRHSHVQGPCYQLDEKILLPKDMAFNLEAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX83</accession>
    <name>A9AX83_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
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    </organism>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4171"/>
    <dbReference type="EnsemblBacteria" id="ABX06803">
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        <property type="gene ID" value="Haur_4171"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG4283">
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    <dbReference type="HOGENOM" id="CLU_1651368_0_0_0"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19368" checksum="43D1BA0B58A1A9B9" modified="2008-01-15" version="1">MSQFDDQDAITVVNLQARIAAGWQELQTFLQGLSHTQLTNPTDAAGWTIKDHAIHLALWENSLLALLKAESRAASFGLDEAVWQQGYEAVNRILQQRYHDLPLDQVFATLETNHQTLLAYISQLSDSDLMRPHREFQAGSTNDEPIIGWIVGNTFEHYAEHLPWMQAILDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX96</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4184"/>
    <dbReference type="EnsemblBacteria" id="ABX06816">
        <property type="protein sequence ID" value="ABX06816"/>
        <property type="gene ID" value="Haur_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4184"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_818287_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4231-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
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    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF140453"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="37814" checksum="03BED69EBFD1D018" modified="2008-01-15" version="1">MQPLIAGEWQGQAAQRCFQEFESVIVPTYQRLINVFDTSAQVTLEIAKLMQAAEAEAAALFSINASSSKNRLMVDPLELPDLPHTEPLDGSKTLKPELITMPSPPPPPTQPNTGDGSGTHGAMGQPTEQDKANHSKMSRAATLARFSGVFSETGYHMQHFLNNSGEPLTVSVDDMLDDMPVFKSKVEFRYENEIIPQINQKLRSDYHGEPLEFHVTIPWKSNFYPDRSENKNWYYAVGGFSYAQTAYVRVTPALDGTPNVEVISQVHMFDRYNWDQGKAVTIPSSGIEWIDNSTIANDHITDEEMGRLHGTGIAQEYDLTGTSSGQKHFYTYDSFIGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXD5</accession>
    <name>A9AXD5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_4223</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4223"/>
    <dbReference type="EnsemblBacteria" id="ABX06855">
        <property type="protein sequence ID" value="ABX06855"/>
        <property type="gene ID" value="Haur_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4223"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_118613_4_0_0"/>
    <dbReference type="OMA" id="MIRIEMK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4270-MON"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005085">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="115" mass="12289" checksum="29D57B349ED686D1" modified="2008-01-15" version="1">MRHIVEDLIRVEGVIGSLLVGRDGLVIASTLIEDEDAEVLGAMSAAVFGEIDKATKRIGIGTLVDAIIDAKDGSILLLEARDVILTVVTQRMVNLGLVKIEMRRAAKNISKAVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN3</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03447">
        <property type="protein sequence ID" value="ABX03447"/>
        <property type="gene ID" value="Haur_0799"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0799"/>
    <dbReference type="HOGENOM" id="CLU_1341722_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-812-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="204" mass="23751" checksum="026517B92EC2E5B0" modified="2008-01-15" version="1">MALATFRLNFLPRLRDGRQIRRYRHHLLEGESLVGSQPLLPHLQRLPLQFQQVEGGPSMTLRDALRETPRLALIEPGSRSLAMRQLCLQWARGAQLPTAYLPLLYQVQQPLSRLTQPLHLLHQEIEKLGFAMTELAVKRGLAAGLWLLLIEGWDQLNQSDQQRWSHWVSSWLERYPALSMMLSTSKPQTIPHQFALWHSVQWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY21</accession>
    <name>A9AY21_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4271"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06903">
        <property type="protein sequence ID" value="ABX06903"/>
        <property type="gene ID" value="Haur_4271"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4271"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_0"/>
    <dbReference type="OMA" id="TRYGFEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4323-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="191"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="369" mass="41107" checksum="FCA1BF708A7BE1BC" modified="2008-01-15" version="1">MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFIDRARLAWGPLRRAYAWRKLAERLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTAYHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRTASVVYNGVDVEHFRPLALDPALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQLGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGYDDVVQAGSTGERFIAQNSADLARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVEVVYEGLVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY39</accession>
    <name>A9AY39_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4289</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4289"/>
    <dbReference type="EnsemblBacteria" id="ABX06921">
        <property type="protein sequence ID" value="ABX06921"/>
        <property type="gene ID" value="Haur_4289"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4289"/>
    <dbReference type="eggNOG" id="COG0171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_395744_0_0_0"/>
    <dbReference type="OMA" id="CEDAWHS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4341-MON"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="622" mass="68715" checksum="D12D3C42C5C43B21" modified="2008-01-15" version="1">MYTLALAQFRPRKGHYAANLARLGEIFAQLGTTERQPDVLMLPETALTGYFLEGGVREQAVTAGQLFHDLQQTYVAARGADAPALDIVIGFYERWRERFYNSALYATIGSDQSLAGIRHVHRKMFLPTYGVFDEARFVEAGRQIAAFDTRFGRVAILICEDAWHSLSGTVAALDGAQMLYVVSASPARGANEDRPSNLARWDDRIREIAGEHGVYLAVCQIVGFEGGKGFAGGSVVVGPRSDERARAPLWSEAVILVDIDLSDLTLARADLPLLADLEERLPFMLRDVHAASEGQHRPSTWDTALSSDSQGLNDASSYQRTVDSEGEKRAKATVGNQSFPIIAAPRFDPESDEPLRINPELTINWLVEFLRDEVGFRRGFKQVVIGLSGGVDSALTTYLCAKAFGAENVLAVRMPYRTSSSDSLDHAQLVIDDLGIQHRTIEITNAVEGYLSFEPDADGRRRGNVMARTRMIVLFDQSQKLGCIPIGTGNKTERLFGYYTWHADDAPPVNPLGDLFKTQVWELASAIGVPDVIVHKPASADLVVGQTDEDDFGISYRKADRVLAYLLSGYRPEQLVARGFNPDEVAIVQRRVNSTHWKRHLPSTAMLSSTAIGKYYLRPVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY47</accession>
    <name>A9AY47_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">R2K_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4297"/>
    <dbReference type="EnsemblBacteria" id="ABX06929">
        <property type="protein sequence ID" value="ABX06929"/>
        <property type="gene ID" value="Haur_4297"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4297"/>
    <dbReference type="eggNOG" id="ENOG502ZCEF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982509_0_0_0"/>
    <dbReference type="OMA" id="RWIVIEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4349-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025643">
        <property type="entry name" value="R2K_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14243">
        <property type="entry name" value="R2K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R2K_3" evidence="1">
        <location>
            <begin position="157"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33419" checksum="7177B8706EBD6B60" modified="2008-01-15" version="1">MVVVLSEATVQHQHTTNARELNRITETARMLGLRVYSLPSEPTQWQVIDDVLAYVPSFDQPQIGIWVGYIPTPAQYTALYQAASAHNIWLINTPEQYQTAMEFDRFYPLLEQLTPESCIITELDQLPTAVASLGLPVFVKGAIKSNKEQGWQACVATTMVELYRLSQQLLSQPAQSRGRVILRRLVQLRTIDSAYQAFPLGREYRVFIYRQQVLAYGFYWDETSAAQTLNPAEVYSIKTLALEAARRVATPFVAVYIGQLHNGDWIVIEVGDGQFSGLSQVSVFELWSQLKAQLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC6</accession>
    <name>A9AYC6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0860"/>
    <dbReference type="EnsemblBacteria" id="ABX03508">
        <property type="protein sequence ID" value="ABX03508"/>
        <property type="gene ID" value="Haur_0860"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0860"/>
    <dbReference type="HOGENOM" id="CLU_1530503_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-874-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="19924" checksum="83FF25DBFB4F0D85" modified="2008-01-15" version="1">MHWYVPASLALIWLLSPRWVIGSPLQSIINQSIQPFNRNGVGFADIPLLRYVLILTFAIGILSWCGGLFERSRLLGGIFIILLGISWFIAEIIIINGSAPLIWSVSFGELERYRLFSEHIILTGIVALALMIPIVLSQWFVRRPIFLWVFDYGALWITLMALCMIKYGAISSMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL3</accession>
    <name>A9AYL3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2351"/>
    <dbReference type="EnsemblBacteria" id="ABX04991">
        <property type="protein sequence ID" value="ABX04991"/>
        <property type="gene ID" value="Haur_2351"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2351"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_5_2_0"/>
    <dbReference type="OMA" id="SQQIARM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2379-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="34"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="318" mass="34554" checksum="AB605CEB3A12ACF9" modified="2008-01-15" version="1">MRIVVAGSIAYDYIMVFPGQFKDHILADKVHVLSVSFLVESMKRMRGGTGPNIAYNLALLGERPTVMGTVGEDFSEYRTWLENAGVDTGLIKVIEGDFTASCFINTDLSDNQITAFYPGAMAQAHRQRLPLDGHRPDFVIIAPNDPAAMAQLVIECQTNNIPYLYDPSMQAPRMNGPELLAGCRSAAALIGNDYEFAMMAEKIGCTEEELHQVVGLTVVTKGGEGATIYQNGQVYEIPAAKPTIVADPTGAGDAFRAGFVRGYLAGLPMPVTGRIASLTACYAIEHHGTQEHRHTKAEFMARYEENFGAEPLLAELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYM0</accession>
    <name>A9AYM0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2358"/>
    <dbReference type="EnsemblBacteria" id="ABX04998">
        <property type="protein sequence ID" value="ABX04998"/>
        <property type="gene ID" value="Haur_2358"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2358"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="MSHPGQL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2386-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="26351" checksum="22C84734777DDC54" modified="2008-01-15" version="1">MAQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELGGLDFMRAWNKEAETPIILLTAKIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRSYKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEILATLMASPGHVFSRLDLLDRTSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV1</accession>
    <name>A9AYV1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ordered locus">Haur_4359</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4359"/>
    <dbReference type="EnsemblBacteria" id="ABX06991">
        <property type="protein sequence ID" value="ABX06991"/>
        <property type="gene ID" value="Haur_4359"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4359"/>
    <dbReference type="eggNOG" id="COG0167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013640_2_0_0"/>
    <dbReference type="OMA" id="ERIKMGA"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="50"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="116"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="67"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="318"/>
            <end position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX06991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="38450" checksum="05B8D2C1E678739F" modified="2008-01-15" version="1">MRSYQLAKALLFRLPPEKAHRLTTLGLDLATRLPFTSALFRSFHHNDPLLKTNLCGLTFNNPVGLAAGFDKDGTHIRGMSQLGFGFLELGTVTPKPQAGNEQPRLFRLIEDHALINRMGFNNAGIAALAQRLAKQPRIIPLGINLGKNKITPNEQAADDYRQGINLLGEYADYIVINISSPNTPGLRELSRREPLTELLQVVKTARQQLRHQAPLFVKLSPDEDREGLEAALGAALDAGVDGIIATNTTVSRENLRSAQQTETGGLSGAPLKTKALATLKYIYQTTNGKLPLIGVGGIANGQDAYERILAGASAVQLYTSLIYAGPQLVGTINRELAALLRRDGFDSIQTAVGSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY8</accession>
    <name>A9AYY8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4396"/>
    <dbReference type="EnsemblBacteria" id="ABX07028">
        <property type="protein sequence ID" value="ABX07028"/>
        <property type="gene ID" value="Haur_4396"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4396"/>
    <dbReference type="eggNOG" id="ENOG502Z9CE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045653_1_0_0"/>
    <dbReference type="OMA" id="HPLKTFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4450-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043773">
        <property type="entry name" value="DUF5716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18982">
        <property type="entry name" value="DUF5716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="476" mass="53868" checksum="407B7FF66DF6B2EB" modified="2008-01-15" version="1">MASAGEMRATMSLFETVPTTLFRPLASPGAAIYTQVLLALFAATKQQSQPLSRERALSLVEQQLELPNAEALTSDAHEEESELEQNNHASAILRSLRAWGWLRFEQQSDYSSAIILPDYAFRLLQLFEDLATKQRQHLRGMICGIHDVLEKACTGDAPHDRLSNAYEQTLFLTQALKELQHNIGLHIQKVLQTLKTKDVLEHVFGTYRKDIVDQAYHQLRTSDHLSRYRPAILQFLQKIERTNLLELSAQHLVSRGEAASFEVAYNRLTDQIDTIRSHFDQLDQLIGVIDLRHSQFVDSAVRNIELFLSASTSTSGQLHRILSQILPNQQAFEQASPEISEMLSIYEFQLTDQQSLSAPTRAAVPFEIQAESYAPLSEAEIAQAQADTLRQLRRSISRDRVRRYALQLLGDAEQRRGSEIELEGVDDLSLIIYLRSYGDGSLGYTVESIDDGVWVERDGVGFRDFLVRRVSTEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYZ7</accession>
    <name>A9AYZ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4405"/>
    <dbReference type="EnsemblBacteria" id="ABX07037">
        <property type="protein sequence ID" value="ABX07037"/>
        <property type="gene ID" value="Haur_4405"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4405"/>
    <dbReference type="eggNOG" id="ENOG5033BDY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162511_0_0_0"/>
    <dbReference type="OMA" id="ISIPYEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4459-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="102" mass="11233" checksum="B7B96E2F19392FF6" modified="2008-01-15" version="1">MGLIARVLEAAGISTVSFFLLAEIAQQLGIPRGLSVKFPFGHVLGEPDNLAQQQLLINHGLNLLINAAQAGTFIQLPYRWKREDWPRLLEAQQADLAQSDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ35</accession>
    <name>A9AZ35_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="17">BCAT</shortName>
            <ecNumber evidence="17">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ilvE</name>
        <name evidence="18" type="ordered locus">Haur_4443</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 17">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 17">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 17">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 17">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 17">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 15">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="17"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4443"/>
    <dbReference type="EnsemblBacteria" id="ABX07075">
        <property type="protein sequence ID" value="ABX07075"/>
        <property type="gene ID" value="Haur_4443"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4443"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_3_1_0"/>
    <dbReference type="OMA" id="GMQCYEG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4498-MON"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17 18" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 17 18" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABX07075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="33779" checksum="32F03DDE3E4DB44E" modified="2008-01-15" version="1">MSIKPTKFIWMNGELVEWEKATVHVMSHALHYGSSVFEGIRAYNTPNGPAFFRLQPHLRRLYDSAKIYRMPIPFDQAQLADACHAAVRENGLNSAYLRPLAWRGYGVLGVNPLAAPVDVMIAALEWGAYLGPEALELGVDVCVSSWNRTAPNTIPTMAKAGGNYLSSQLIVMEATLNGYAEGIALDVNGVLSEGSGENLFIIRDGVIYTTPVTAAILPGITRDSVLTLAKEYGYEVREQALPREILYLADEMFFTGTAAEVSPIRSVDGVQVGEGKRGPITTVLQEAFFGLFNGKTEDKWNWLEYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ68</accession>
    <name>A9AZ68_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0966"/>
    <dbReference type="EnsemblBacteria" id="ABX03614">
        <property type="protein sequence ID" value="ABX03614"/>
        <property type="gene ID" value="Haur_0966"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0966"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006954_2_0_0"/>
    <dbReference type="OMA" id="SIMAYAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-980-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734442" evidence="2">
        <location>
            <begin position="24"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="709" mass="74408" checksum="EFBF49474660F8D2" modified="2008-01-15" version="1">MQTKRSLIAIGLALAIALLSVFAASSLTPSSAASSSDGLWQDVAEQRIQQKGQRDIVPLVYRTVSLDLAGLSQRLDQAPLESAVQVQQSAFLLSLPLPSGQFRQFRVVESPIMEPALAAKFPELRTYLAQGYDDPEMVARLDLTPSGFHGLILAPEGRYFIDPYSRNDTGNYIVYDSRNFVADPSKLASKGKTDYVGETPITNPFPERYSIGETLRTYRLAMAATGEYTSFHGGTVNGAMAAIVTSVNRVNTVYERDISVRMVLVANNNLIVYTNGGTDPYTNDDGFEMLGENQTNLTSVIGNANYDIGHVFSTGGGGVAALGSVCVSGSKAEGVTGSPAPVGDPFDIDYVAHEVGHQFAGNHTFNGTTNACGGGNREGPAAYEPGSGSTIMAYAGICGSENLQPNSDPYFHVKSLEEMSAFITTGAGASCGTTAATGNTPPTANAGADFTIPANTPFELTGSGNDVNGDSLTYNWEQYDLGSASPPNTDNGNRPIFRSFDSTTSTSRSFPRLTNILNNSTTIGESMATTNRTMNFRLTVRDNRAGGGGYGLDTARVTTVNTAGPFQVTAPNTAVTWAGFSSQSVTWNVANTTAAPVNCSNVNILFSSNGGTSFSPVLSNTPNDGSESITVPNVATTTGRIKVQCAGNVFFDIGNANFTVTASNATVTPTSDATATPTITPTATATVTPSVTATPSTSMVYLPVAMKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD4</accession>
    <name>A9AZD4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2438"/>
    <dbReference type="EnsemblBacteria" id="ABX05078">
        <property type="protein sequence ID" value="ABX05078"/>
        <property type="gene ID" value="Haur_2438"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2438"/>
    <dbReference type="eggNOG" id="COG0351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020520_0_0_0"/>
    <dbReference type="OMA" id="DNRHTHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2466-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="1">
        <location>
            <begin position="12"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="27648" checksum="2D7D5FB2CF00A39F" modified="2008-01-15" version="1">MRAKALTIAGSDSGGGAGIQADLKTFHTYQVYGSSVITAITAQNTIGVQAFELVSPSLIERQIVAVLADIGADAIKTGMLGNAAIIETVANSLRQYPVALVVDPVMVAKSGDRLLAEEAVQALCEHLVPIASLITPNLPEASVMLGREIADERTMYAALDDLLKLGAKAVLLKGGHLKGQPLDLFADGQQVLELRSERIDTPNTHGTGCTYAAAITALLARGEDLVSAVCQAHAFLYAAIASAESIGAGHSPVNHWAWLNERTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZS7</accession>
    <name>A9AZS7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="10">ATP-PFK</shortName>
            <shortName evidence="10">Phosphofructokinase</shortName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pfkA</name>
        <name evidence="12" type="ordered locus">Haur_4499</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4499"/>
    <dbReference type="EnsemblBacteria" id="ABX07131">
        <property type="protein sequence ID" value="ABX07131"/>
        <property type="gene ID" value="Haur_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4499"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_0_0_0"/>
    <dbReference type="OMA" id="TNRDNPF"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="5"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="280"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="117"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="10">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="38161" checksum="43A259FD6B42F09E" modified="2008-01-15" version="1">MAIRKVAILTSGGDAPGLNGVIRAFVKSAVLEHGWEVVGIEDGFEGLVGTPRLRPLGLKEVRGLLGRGGTILGSTNKGNFGWHKNADGELVRNDASYQEFVANAKAEGIDAVVVLGGEGSQSIAHDLGSFGLPVVGVPKTIDNDLVGTDQTFGFDTAIGVATDALDRLHTTAESHDRVMVLEVMGRHAGWIALHAGLAGGVDAILIPEIPFDLRALAHKIGERDAFGSSFSIIIVAEGAMPAGGEAIYQREGLLGGIGYYVANQLAELTGKDTRAVVLGHIQRGGSPTPIDRILASRYGVGAVWAISQGRFGQLVAIQNDQLITVPLLECANKIKPVPVDGQMVRTGRSLGIVFGDEEQRINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY7</accession>
    <name>A9AZY7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1046"/>
    <dbReference type="EnsemblBacteria" id="ABX03694">
        <property type="protein sequence ID" value="ABX03694"/>
        <property type="gene ID" value="Haur_1046"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1046"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902465_0_0_0"/>
    <dbReference type="OMA" id="MWGWKEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1063-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="33149" checksum="9FF044CF4CFF7D1E" modified="2008-01-15" version="1">MSYGNDDSQRERNDAVLKALGGVPQPPVAPSVQPQQPMAQPGWHPVDQGYQVPPVLIAEEGKSNTPMAYWVLPDLIFGFLLAVLFQVIIMVGYMLVKGLSSLSDIEGLLTDPTFMLLNAPTLGLGFTLASILRVNILRKLPLAWFGLNGKKLGVALGFGFIAGISFLVTNLISGVIAQALGSNPDQQEQLIGPFKNASNLQIGLFGLFVVIIGPFLEEVFFRGYAFRAIRQKLGVTWGVVLSGILFALPHAFGVTTGYLGLLIPIFLGGAILALVYHYTNNLWSAVLAHSMNNFVGFLGLLAALKLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>A9B073</accession>
    <name>A9B073_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ordered locus">Haur_2544</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="32" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="31 32" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2544"/>
    <dbReference type="EnsemblBacteria" id="ABX05182">
        <property type="protein sequence ID" value="ABX05182"/>
        <property type="gene ID" value="Haur_2544"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2544"/>
    <dbReference type="eggNOG" id="COG0646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004914_4_0_0"/>
    <dbReference type="OMA" id="ADCIAMS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2572-MON"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="26">
        <location>
            <begin position="4"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="27">
        <location>
            <begin position="348"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="30">
        <location>
            <begin position="635"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="29">
        <location>
            <begin position="737"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="28">
        <location>
            <begin position="887"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="747"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1161"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="25">
        <location>
            <begin position="903"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="750"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="795"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="855"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="941"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1107"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="ABX05182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1180" mass="129663" checksum="9150226864B9FC8E" modified="2008-01-15" version="1">MTSIKPYIAELAKRVLIYDGAMGTSLDLYDLKPEDFGGEQYFGARDYLALTRPDIIEQIHSSFMEAGVDVLETNTFQSTRIRLHEWGLADKTYEQNFKAAQLARKVADRYQAQDGRKRFVAGSMGPTGFLPSSDDPTLSNITWDALSDTFKEQTIALVEGGVDVLLVETSVDILEVKAAIDGIRRGLAELKRPDIAIQAQVFLDLSGRMLLGTDIQATMVTLEALADVDVIGLNCSTGPEHMRPAITYLAANSKLPISCIPNAGLPMEVNGETVFPLEPAGFAKSLTEFVQDLGVRVVGGCCGTTPAHLRALVDSIGNNCPPKPNQAPIVPQVSSAMRSLALHQDPGPFIIGERVNSVGSRKVKKLLLKDDYDGVLQIAREQADSGSHALDVCVAMTERPDEKEQMQKLLKKLTMGVELPLVIDSTEYEVIDAALQIYPGRAIINSTSLEGGREQKFDKTMPLVARYGAAIIALTIDEEGMAHTAEAKVAIAKRMAEMGRQEYGVQNDAWLFDALTFPLTTGQAELRESAKETMEGIRRIKAEIPGAMTVLGVSNLSFGIQPHARSALNSVFLYHAVKAGLDAAIINPTHVMPFAEISAETRKVCEDVIFNSDEEALPRFIQYFEANTAVAGEAKVDPTATMNAEERIHWKILHRKKDGIEADIDESRAWREAGGQTQGEAAIDILNGVMLPAMKEVGDKFGAGELILPYVLQSAEVMKRAVAHLEQFLDRVEGTTKGKVVLATVYGDVHDIGKNLVYTILSNNGYTVYDLGKQVPVNTIIEKALEVGADAIGLSALLVSTSKQMPLCVQELHKRNLAFPVLVGGAAINRQYGQRILFPEPEVAYTGGVFYCKDAFEGLETMDKLSDPTVREEYLSVMEDAARESLKAPERGRTLLEKLGKNNPSGVRSTTRNDNPVPTPPFWGVQVAKKIRLDDVTPYLDLNTLWRLGWGIKNLKGAEYDRVVNDEFKPRLRRMIDDAKRNGWLQPQAVYGYFPAQAAGEELVVYDPKDRKTVLTRFAFPRQPSRERLCLADYFRPVESGEFDVVGLQIVTMGHVAAERVESLQKANDYSESFFSHGLSTTYAEALAEFTNKIISQGLGLSYQAKRYSWGYPACPDLEEHTKLFSVLPAKEIDVSLTSAFQLDPEQSTAAIVVHHPDAKYFSIGSVAERAESDVAELTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H3</accession>
    <name>A9B0H3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4560"/>
    <dbReference type="EnsemblBacteria" id="ABX07191">
        <property type="protein sequence ID" value="ABX07191"/>
        <property type="gene ID" value="Haur_4560"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4560"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959225_0_0_0"/>
    <dbReference type="OMA" id="IWIGAGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4615-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="32341" checksum="EFE184B0727BB37D" modified="2008-01-15" version="1">MATIMTAQRQERRQLTTGIRVGRAVMLMPELVVFPALCGLYFLTNQAVGVALLGELLIGLFVARIALVWYAGRAWARGSYAQAERLVLWSLRIYPDSADAWLAMGSIQLAQGETEAAIKAIERADQLYPFHAPIYLEMSRALAAHGDWNEARHYASMALVLDEQLALSYSHNALLSLHFDEASQTTKQWIEAGLALAPHVAAKASLYVARAELAFLANDERQVQLALDQAELLLNGCPIPQQAELLYRIGQLQRSLGQVDAARSSFERIEYSDREGGYVHAAWRAKVETSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I1</accession>
    <name>A9B0I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4568"/>
    <dbReference type="EnsemblBacteria" id="ABX07199">
        <property type="protein sequence ID" value="ABX07199"/>
        <property type="gene ID" value="Haur_4568"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4568"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1607915_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4623-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="16277" checksum="A64ED00A488CB96F" modified="2008-01-15" version="1">MPESFGQRLGRLRALHGWTQQALADRLALSRVAISHFEMGLATPSERTVILLAGLFRLEPHELVADTFYPEGKSLRLPSVAPRYSEVELQLALCARDLAWCERLPAARAEMLLHWQTNLEQLHRNCVDLHERQLIQAMLAQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Q9</accession>
    <name>A9B0Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine phosphorylase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1131"/>
    <dbReference type="EnsemblBacteria" id="ABX03779">
        <property type="protein sequence ID" value="ABX03779"/>
        <property type="gene ID" value="Haur_1131"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1131"/>
    <dbReference type="eggNOG" id="COG0005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054456_0_2_0"/>
    <dbReference type="OMA" id="MTQCPEA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1152-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="27306" checksum="B5E71A40FA26B859" modified="2008-01-15" version="1">MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDVSPPFVNSRANIWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYACSEGPRLETAAEIRAWANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLATAEQLLATNEVSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T9</accession>
    <name>A9B0T9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1161"/>
    <dbReference type="EnsemblBacteria" id="ABX03809">
        <property type="protein sequence ID" value="ABX03809"/>
        <property type="gene ID" value="Haur_1161"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1161"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_643678_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1183-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="220"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="426" mass="47953" checksum="6C1E60C1768AE467" modified="2008-01-15" version="1">MLKTIINRAKNHADPAIVVHYQHLLEHNKRRLIEWIMLLAGGLALPFTLVLIVAVANHQQPSSVLVLHLTRSLLNPLLVWWLLQRKQINWAWHSTMVFAMAHNTVLAYVMHLPNVIIVELFALAGFAVVMPFWQVLAYIGGLIGLNYCFAGQFIVLNEWALVMIVVLSIVLMCSTIGFVSRQTLWHASQQHSQTAELVQQQSSMQQQLHDLQTHVQQLSLLKHDLRQPLKSVQGLLQGLAFEQPSTHSTIQPALAATQRVERQLNNLLDQARQQLGRQRASLEIIDVQHCLGQLQPAISGLAAYYSEPIVKVQLEIDAGSVIVADREQFERALFNLLDNSLSRCHHEVRISSYRSEQNVIIEVRDDGAGMHQALRTALNQADFSAIKQGLGLKQVQQMLTQAQAWLHVPDVAIGCTLQLHFPQATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X5</accession>
    <name>A9B0X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lysophospholipase L2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1197</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1197"/>
    <dbReference type="ESTHER" id="hera2-a9b0x5">
        <property type="family name" value="CarbLipBact_2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03845">
        <property type="protein sequence ID" value="ABX03845"/>
        <property type="gene ID" value="Haur_1197"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1197"/>
    <dbReference type="eggNOG" id="COG1647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076594_0_2_0"/>
    <dbReference type="OMA" id="DWYAEVD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="6"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="28172" checksum="BAEC6CAF4FE93A39" modified="2008-01-15" version="1">MSSVGCLILHGFTSCADSVNRVPSRLAPHHIPYRMPYLRGHGTLPEDLQGVTWHDWYADANAALRDLRREVDKVILIGLSMGGLVANHLAAAHRDDVIGVVSVAAAMRFHYKHADRARYVAPMLGMWGDENRDMGAGWYDKETGRQHGNYRRFPAPAFVSLWRYAKVVEQQLPRITAPILIIHSHQDRTIPTSAAEAIYRQVGSSDKQLLWFDKSGHEMLRDGESPAVLDAVEQFVLHHRAQYQSSTNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G7</accession>
    <name>A9B1G7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4723</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4723"/>
    <dbReference type="EnsemblBacteria" id="ABX07354">
        <property type="protein sequence ID" value="ABX07354"/>
        <property type="gene ID" value="Haur_4723"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4723"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_0"/>
    <dbReference type="OMA" id="ISTHCFQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4781-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="9"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17126" checksum="9937DCC986FC0ECD" modified="2008-01-15" version="1">MTTTTTGKLQVGDQAPRFRLPNQTGALIDLDDLLGKKHIVLFFYPKDDSLICVAEVCAFRDQYEVFKQAGAEVIGVSSDSVESHQQFAAKHRLPFTLLSDGDSAVRKAYGATTLGIFSGRVTYIIDPQGTIQHIFSSRLNAQKHIDESLRILQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1I9</accession>
    <name>A9B1I9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1226</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1226"/>
    <dbReference type="EnsemblBacteria" id="ABX03874">
        <property type="protein sequence ID" value="ABX03874"/>
        <property type="gene ID" value="Haur_1226"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1226"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_0"/>
    <dbReference type="OMA" id="YEPAHPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1248-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="39163" checksum="2B7FE74BA1C404E8" modified="2008-01-15" version="1">MAEAPLLEVKNLQVQFKTADGVVNAVNNVSFSVNRGETLGIVGESGSGKSVTSLSIMRLIPSPPGKIAGGQILFDGDNLVDFSESEMRKIRGNRISMIFQDPMTSLNPVLRIGRQMTESLQLHMGMTPKQARNRAIDLLSMVGIPAPDKRLDDFPHQFSGGMRQRVMIAMGLACNPELLIADEPTTALDVTIQAQILELLNRLKNETGTAIIFITHDLGVVAGMTDRVIVMYAGRVVEQASTNELFHNPRMPYTIGLLDSIPRLDGIQTRLTPIPGLPPDLLEKTERCPFAPRCDFVQEQCWSETPSLRQVAPEHTAACLFEIDREQRQAMAAKKIAEEQAALDAALEDVLAHEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q1</accession>
    <name>A9B1Q1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1288"/>
    <dbReference type="EnsemblBacteria" id="ABX03936">
        <property type="protein sequence ID" value="ABX03936"/>
        <property type="gene ID" value="Haur_1288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1288"/>
    <dbReference type="HOGENOM" id="CLU_134369_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1310-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14868" checksum="6A557F5771F2106B" modified="2008-01-15" version="1">MRWLQHPQLLRYAIRFDGMSAGVLMAGLLGLNQPLAEFFGLPSGFLWYVGLGLIPWVSWLVWLSFRPTIKRGAAWFVVAVNALWLAQSVWLIVGPSFDPTVWGYGFLIAQAILVLLITETEIIALRRKLVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q4</accession>
    <name>A9B1Q4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1291"/>
    <dbReference type="EnsemblBacteria" id="ABX03939">
        <property type="protein sequence ID" value="ABX03939"/>
        <property type="gene ID" value="Haur_1291"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1291"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911452_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1313-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="1">
        <location>
            <begin position="230"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="305" mass="33871" checksum="4B06A09E4D972504" modified="2008-01-15" version="1">MSASFILLINHTSTASIQTNLLMEHGYIPMLLPLNQLAQLPALPHQTIVVACFNNQTELEQLTTTLPTWNMPWIGWNLSGQIELSIAAYKASADIVLTDSCTEQLLLNVLSQRSNYIAGQSDPIVKQRQRHYQRGTLIRLPAEHILLINEGVVGLATLHSDGSQVLVSLCGPQQLVYSTEQQSSVQLYAHSDVVGQVYAWAQVAEHPSLLQRLRSRLSQMERWASMQANGYSDQRILGLLGLLAEQFGKPTEQGTLIDIRLTHEQLASAIGVNRTTTTRLLRDLRNRGLVYTAGHGAQERFCLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T8</accession>
    <name>A9B1T8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACT_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2742"/>
    <dbReference type="EnsemblBacteria" id="ABX05380">
        <property type="protein sequence ID" value="ABX05380"/>
        <property type="gene ID" value="Haur_2742"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2742"/>
    <dbReference type="eggNOG" id="COG3603">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130568_0_0_0"/>
    <dbReference type="OMA" id="STFDGDH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2773-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016540">
        <property type="entry name" value="UCP008459"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008459">
        <property type="entry name" value="UCP008459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT_7" evidence="1">
        <location>
            <begin position="58"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13939" checksum="B2C51FEE03DD4F02" modified="2008-01-15" version="1">MHQLKLTIYPEMLAVARLNVDQPWPEWALQSPFVSISRTTDELSIVCETKCVPANVQAERNWRGLRVVGTLDFSQVGILASLAAPLAQAQISIFVLSTYDTDYLLLREPEFNEAVAVLTAAGHQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X5</accession>
    <name>A9B1X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2779"/>
    <dbReference type="EnsemblBacteria" id="ABX05417">
        <property type="protein sequence ID" value="ABX05417"/>
        <property type="gene ID" value="Haur_2779"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2779"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_0"/>
    <dbReference type="OMA" id="DPGEMDT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2810-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="23618" checksum="2669F5596B031A05" modified="2008-01-15" version="1">MQRIGLITGASRGLGLALAQQLALNGWHLIITGRGATALEQARAALATHTTVQAIAGDIADPAHRQALAVATQAWGGLDLLVNNASILGPSPQPNLLDYPLDNLAQVYAINVFAPLAAIQTLAPSFKPSIRIINISSDAAVQAYEGWGGYGSSKAALDQLTAILAAEQPTWRVYALDPGDMNTQMHQEAFPGEDISDRPPPEASVPTILRLINDDLPSGRYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y6</accession>
    <name>A9B1Y6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX05428">
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    <dbReference type="OMA" id="DVEVCHW"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Flavoprotein-like_sf"/>
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        <property type="entry name" value="FMN_Rdtase-like"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="19975" checksum="E314AA0992B3D66D" modified="2008-01-15" version="1">MVDVVTLAGSPAPRSTAAALLEHSKTILERHALVVKSMSVRDIPPEELIGQAQFSPAVRHYSQLIRQAGALIVATPVYKDTYAELLRAWLNLLPTGILRNTLVLPIITGSSARTEAQIYADLATRFRQLGAKHIIPSLFAAEQQIQLLGSKLPPRIHRSLEERLGLALDDIAQQLGVLPLAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z0</accession>
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    <reference evidence="3" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2794"/>
    <dbReference type="EnsemblBacteria" id="ABX05432">
        <property type="protein sequence ID" value="ABX05432"/>
        <property type="gene ID" value="Haur_2794"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2794"/>
    <dbReference type="eggNOG" id="COG1232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051347_0_0_0"/>
    <dbReference type="OMA" id="HREPYAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2825-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
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    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="48513" checksum="7E5EAAA6FBF22D6A" modified="2008-01-15" version="1">MKTIAVIGAGFAGLSAAYDLACAGHQVTVYEAAPQVGGLAAGFQAEGWDWSLEKFYHHIFGSDKALLDFIKEIRADDLLFFNSPVSGQWDAQRGSIEIGGIIPLLTYPHLSVFNRLRNAAGGAWLKFLAIIDRWQHLEKTTAERYIQKLMGKPAYEAMWKPVLEGKFGPYTPEVNAAWFWARIASRTFKLGYFRGGFQALGERMAEAVRQKGGTIRLNSPVQELRKIEQGWLVISNDQASYDQVLSTTSPGLLKRMTPDLPASYTAKLDQLKSIGAVVLTVALKQSLTNGMYWMNMDKKHFPFLALVEHTQMIDRRHYGGQHLVYLGDYLEPSHEYFQLSKEELLERFMPSLSKVNPQFKPDWIEGVWLHREAYAQPIVPVNHSQAIPALKTPLEDLWWASMSQVYPWDRGTNFAVEIGRRAAKEMLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K1</accession>
    <name>A9B2K1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
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    </protein>
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        <name evidence="3" type="ordered locus">Haur_2814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2814"/>
    <dbReference type="EnsemblBacteria" id="ABX05452">
        <property type="protein sequence ID" value="ABX05452"/>
        <property type="gene ID" value="Haur_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2814"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2845-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
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        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="152"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="108"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="26601" checksum="2644EC0991D6CF91" modified="2008-01-15" version="1">MQQAPTKPRWQPDLSETTFNGLRALLISSAATLGLIAIFWWLTSLINPEISQFDRAGLAGGFWLRTQLPYLNPIFHLATWIGTLYGLALQTLIVGYWLYRRKPAAWRSRLSLIILALLGAAIWMTLLKQGFARPRPSIFEPAYQISTYSFPSGHAMAAAAWYGSMAIALSYGHTQSRRWGIIIGLAAMAVLIGTSRVVFAVHYPTDISAGWIGGIAWLACLRAVWHGISWQRQRRQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P9</accession>
    <name>A9B2P9_HERA2</name>
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        <recommendedName>
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        <component>
            <recommendedName>
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        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">S-adenosylmethionine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
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        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine</text>
            <dbReference type="Rhea" id="RHEA:15981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="4.1.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2862"/>
    <dbReference type="EnsemblBacteria" id="ABX05500">
        <property type="protein sequence ID" value="ABX05500"/>
        <property type="gene ID" value="Haur_2862"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2862"/>
    <dbReference type="eggNOG" id="COG1586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125470_2_3_0"/>
    <dbReference type="OMA" id="FALHANE"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006557">
        <property type="term" value="P:S-adenosylmethioninamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00464">
        <property type="entry name" value="AdoMetDC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 9" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3 9" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023572203" description="S-adenosylmethionine decarboxylase beta chain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023572202" description="S-adenosylmethionine decarboxylase alpha chain" evidence="9">
        <location>
            <begin position="72"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for processing activity" evidence="9">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for catalytic activity" evidence="9">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autolysis" evidence="9">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14255" checksum="E27EE3C32723505C" modified="2008-01-15" version="1">MSNFIQSPIYPAAGRHLLANLGGCSAAILNDRDLLQTIVMQAANATNATVLEIVAHQFTPHGVTIVAVLGESHASLHTYPEHGAAFWDCFTCGEQCQPEASLGVLVPALHATNVHSQLIDRTISEVTQTAPSTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S2</accession>
    <name>A9B2S2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2885"/>
    <dbReference type="EnsemblBacteria" id="ABX05523">
        <property type="protein sequence ID" value="ABX05523"/>
        <property type="gene ID" value="Haur_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2885"/>
    <dbReference type="eggNOG" id="COG4636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076312_6_2_0"/>
    <dbReference type="OMA" id="TPNHNKI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2916-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="21917" checksum="74B4F0F0B3A1279A" modified="2008-01-15" version="1">MSAEAIPSKTFDEYLAIEKETGIKHEYYQGKVYAMTGASARHNLIVSNIIASLHQQLRQSPCRVFPSDLRLQISQTGLYTYPDISVACGTLEFGSERPDTLLNSTCLIEVLSPSIENYDRGMKFEHYRTISSLQIYLVIAQDRCHCELYLRQTDHRWLLIEFWSLEQTIQLEAINAQLKLNDVYEYIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T8</accession>
    <name>A9B2T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdenum ABC transporter, periplasmic molybdate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2901"/>
    <dbReference type="EnsemblBacteria" id="ABX05539">
        <property type="protein sequence ID" value="ABX05539"/>
        <property type="gene ID" value="Haur_2901"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2901"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065520_0_0_0"/>
    <dbReference type="OMA" id="CDVFIPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2932-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734510" evidence="3">
        <location>
            <begin position="25"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="41972" checksum="3CBFE3054B0C33F1" modified="2008-01-15" version="1">MKQIRRIGLFVLSLSLLACGAATTSVPTTPAAPTTSTNPTPTLSGEINVFAAASLTGAFTEIGNTFQTSHPNTKINFNFAGSDQLATQITQGAPADVFASANSTQMQVAVDAGMIDGSMLQPFARNRLIVVYPQSNPAQIQSLQDLAKPKLKLVLASASVPVGNYALDFLAKASALPEFGTSYSPTVLLNVVSYENNVKAVLSKVSLGEADAGIVYSTDAASISDSSIGTLAIPDQLNTIATYPIAITQNSANSQLAQAFVDFVLTPAGQQILARYGFITVTDPSALSPYQLLIAGNLTTPLTLTAELIENYEQQQVEFNGQSYRGLGFGQLLMQIQPKSNARTFSLLSSDGSQTVLAIADLTADPRAIIAAEADGSFTSIIPSNPNASQLKNIVKITVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U6</accession>
    <name>A9B2U6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YhhN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3373"/>
    <dbReference type="EnsemblBacteria" id="ABX06009">
        <property type="protein sequence ID" value="ABX06009"/>
        <property type="gene ID" value="Haur_3373"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3373"/>
    <dbReference type="eggNOG" id="COG3714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1193504_0_0_0"/>
    <dbReference type="OMA" id="LFFPHIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3410-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31885">
        <property type="entry name" value="PTHR31885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="232" mass="25459" checksum="6D829789B28910F3" modified="2008-01-15" version="1">MDALSAMMQLWLGGLLVAWALVLLGGFVLGKPNAEGTRRMTLWGRLGSSAILVVAAWSWWWQLRAQHNLTALLLALGMSLGFVGDLCMAQVFPLKNYVLGGMSAFGLGHVAYIWAGLRIESFNVLSWLIWLIVGALGWYVVVWHDSSRSRLHQVALPYALLLASTTGIATGVALEQLSMLTFAFGAALFLLSDLILATQLFNDARWRGIGDVVWFTYGPAQALIVYSMAWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B334</accession>
    <name>A9B334_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4867"/>
    <dbReference type="EnsemblBacteria" id="ABX07497">
        <property type="protein sequence ID" value="ABX07497"/>
        <property type="gene ID" value="Haur_4867"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4867"/>
    <dbReference type="HOGENOM" id="CLU_939331_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4927-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33557" checksum="D60BCE6E0FC97CCA" modified="2008-01-15" version="1">MMTVHSLPTAIHAVYHSLIDHPRWHNFGKRTFGSWRDLLLIEAVVRYPRQTLHGYVNYLHYYTPLIVASVLEKALRKGWLVLERGKYEPGPHYLAYLIERADLIQELFDVWPEAAAHAVAEYGERLCEAIPTQACLDHLLYAYGPRPSAHKAITFEERALMVCTALSNYRADAKALAWQACGISPAQGMILRSIVKHHNPISRPDLLIAVDPYLGICAESTIDGLLAQQWITRDDRGLRLNATGWGYWHAARSALRQRIAQLYSVLDYHETQAFIMGAQTLVNTTKYVFAQHLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B344</accession>
    <name>A9B344_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UBA/THIF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4877"/>
    <dbReference type="EnsemblBacteria" id="ABX07507">
        <property type="protein sequence ID" value="ABX07507"/>
        <property type="gene ID" value="Haur_4877"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4877"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_10_1_0"/>
    <dbReference type="OMA" id="SAKWKLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4937-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="11"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="343" mass="37179" checksum="CA4ACFB2EBEB9D40" modified="2008-01-15" version="1">MPSSGIPSARYSRQTRFAGLGQAGQQRLAQARVAIVGLGATGSTIAHALLRAGVGYLRLIDRDWVEEHNLPRQSLYTEADAAQLVPKVVAAKAHAQRINSACDIEALVLDLHAGTIDQALAGVDLIMDGSDSLETRLLINQWCVREGKPWIYSGVLGGHGMTANFRPKQACWRCVFTTSPEPGSMPTCETAGVIGPVVGVIGNLAATEALKLLSGQGQANPDLYMLDLWAWQFEQLPLPTPRPDCPVCGLRQFDLLEQDSAPTLSLCGRNAIQIRPQQPITMALAQLAAHLQQADLRVIQTDYLLRFAAETLQATVFPDGRVIISGTDDPALARGFYNRWINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9B380</accession>
    <name>A9B380_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ordered locus">Haur_0118</name>
        <name evidence="11" type="ordered locus">Haur_4913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0118"/>
    <dbReference type="EnsemblBacteria" id="ABX02770">
        <property type="protein sequence ID" value="ABX02770"/>
        <property type="gene ID" value="Haur_0118"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07543">
        <property type="protein sequence ID" value="ABX07543"/>
        <property type="gene ID" value="Haur_4913"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0118"/>
    <dbReference type="KEGG" id="hau:Haur_4913"/>
    <dbReference type="eggNOG" id="COG0050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_1_0"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="43728" checksum="02A4061709416686" modified="2008-01-15" version="1">MAKQKFERNKPHINIGTIGHVDHGKTTLTAAITKTMALRGRAEFRAFDQIDNAPEERARGITISISHVEYETENRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAPDGPMPQTREHILLAGQVEVPAMVVFLNKVDMMDDPELLELVEMELRELLSKYGFPGDEIPIVRGSAKGALDSASTDASQPEYQSIQELMQAVDDYIPTPERAIDKPFLMPIEDVFSIKGRGTVVTGRIERGIVKVGDTIEIIGMGPDVRTTAVTGVEMFKKLLDEGRAGDNVGALLRGIERTDVERGQVLAKPGSIKPHTKFKAEVYVLKKEEGGRHSPFFSGYRPQFYVRTTDVTGAIGLPEGVEMVMPGDNIQMTVELIVPVAIEQGLKFAIREGGRTVGAGIVTEIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U7</accession>
    <name>A9B3U7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3447"/>
    <dbReference type="EnsemblBacteria" id="ABX06083">
        <property type="protein sequence ID" value="ABX06083"/>
        <property type="gene ID" value="Haur_3447"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3447"/>
    <dbReference type="eggNOG" id="COG2949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051474_0_0_0"/>
    <dbReference type="OMA" id="IDAWGVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3484-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="52"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="233" mass="25893" checksum="ADFDA3ED938C04F2" modified="2008-01-15" version="1">MSNRLQPRKLLKLGLRLALLAILGLLLVNGWVRWATADYRFADVASIPSQPVAIVFGAGIRYNQPSAALRERLDGAIQLYQAGRVQHLLMSGDNSQTNYDEVSVMRDYAIAHGIPASAITRDYAGFSTYETCYRAKAIFGVNQAILVTQDYHLPRAIYTCRELGVAAIGLSIPDWNFKPEQSTTYYPPATQIRYTTREWLARCKALFEVHISQPQPTFLGPAVGLGEIASTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B409</accession>
    <name>A9B409_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ordered locus">Haur_3509</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3509"/>
    <dbReference type="EnsemblBacteria" id="ABX06145">
        <property type="protein sequence ID" value="ABX06145"/>
        <property type="gene ID" value="Haur_3509"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3509"/>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028104_2_0_0"/>
    <dbReference type="OMA" id="DITYQLR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3546-MON"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="105"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="302"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="107"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX06145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="47184" checksum="2B06C79C9C900CCF" modified="2008-01-15" version="1">MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGIDRLLVTSALPLDHIEIVAAHQAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAVIFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYARTFLALSPAIGIITNLDWDHVDIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGAARRFEPKGQVGAVRVFDDYAHHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLADFQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNALAVGDLDQAFEQLLRDVQAGDVVLTLGAGDGVVVGERLVAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B411</accession>
    <name>A9B411_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ordered locus">Haur_4914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4914"/>
    <dbReference type="EnsemblBacteria" id="ABX07544">
        <property type="protein sequence ID" value="ABX07544"/>
        <property type="gene ID" value="Haur_4914"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4914"/>
    <dbReference type="eggNOG" id="COG0051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_4_0_0"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8628" checksum="D0883CD971258CAD" modified="2008-01-15" version="1">MDAAERTGAQVAGPVPLPTKIEKYSVLRSPFIDRDSQEQFEIRTHKRLIDVIDPSQQTINALMKLNLPAGVDIEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B475</accession>
    <name>A9B475_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4978"/>
    <dbReference type="EnsemblBacteria" id="ABX07608">
        <property type="protein sequence ID" value="ABX07608"/>
        <property type="gene ID" value="Haur_4978"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4978"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047963_1_0_0"/>
    <dbReference type="OMA" id="FKSEVQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5041-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022128">
        <property type="entry name" value="FhaA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042287">
        <property type="entry name" value="FhaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12401">
        <property type="entry name" value="DUF3662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="27174" checksum="A0CAAC5157CD8840" modified="2008-01-15" version="1">MSALSRFEQFMEGMVEGNVARLFRSPIQPAEIGKRLERAMESQQTISMDRILVPNAYKAHLHPDDYKAFEPVKTNLQHEMARYLAELARERGFTMINHPNVELVADPAVKQRSIMIDGQISEAPAHLGGNTQMIGPNGAAMTGQPATPKANLILYTDQGEHRIPVKKSVTNLGRGLNNDLILEDSRVSREHAQLRYRARRFWVSDVRSTNGTFVNGDPVQERELRNGDIVSLGGLELRFEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B490</accession>
    <name>A9B490_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4993"/>
    <dbReference type="EnsemblBacteria" id="ABX07623">
        <property type="protein sequence ID" value="ABX07623"/>
        <property type="gene ID" value="Haur_4993"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4993"/>
    <dbReference type="HOGENOM" id="CLU_1684161_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5056-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732441" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="156" mass="16048" checksum="85C364CCD7CCDD4A" modified="2008-01-15" version="1">MKRLWLGLLLLVLASCGGATPTSVPATATTAPTATSAANPEVLLTFAQTGGIAGINETLTIWSDGKLELASVSAASTLRVGAATPEQLTALQTILNDPAFASLAPSYGDLGSCCDMFSYTLTTGNKSIATIDGAAYPEILAKLFEQLQTLKQSIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B499</accession>
    <name>A9B499_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
            <ecNumber evidence="2">3.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0004"/>
    <dbReference type="EnsemblBacteria" id="ABX02656">
        <property type="protein sequence ID" value="ABX02656"/>
        <property type="gene ID" value="Haur_0004"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0004"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_0_1_0"/>
    <dbReference type="OMA" id="GLHNAPE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047980">
        <property type="term" value="F:hippurate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="191"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="399" mass="42451" checksum="09B8559A9CE581C5" modified="2008-01-15" version="1">MASRPDFRYVAHTLVEQLITDRRDLHQHPELGFEEFRTAKIVADRLRELGYEVTEGVATTGVLGHIPAQPGGKVAMLRFDMDALPIHEQNDVDYRSTIDGKMHACGHDGHVAIGLGVAAALMQNREALGTGGIKLLFQPAEEGGGGAQKMVEAGAMQNPRPDISLGLHIWAPMPLGKANVRSGPIMASADTFIVEITGKGGHGAQPETTVDSVLVASHMVVALHSIVSRNVHPEQPAVLSVGSVQAGTAHNIIAHNATLTGTIRSYDPEARERLKQRVHEVVQGVAATFGATATLKYDEMCPATICDPAATALVRGAAEAILGAENVDDSVRTMGSEDMSVLLNEVPGCYFFLGGQTLERELGAHPHHHPAFSFDEGVLPLGVAILCEAATRYLNGSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G1</accession>
    <name>A9B4G1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0066"/>
    <dbReference type="EnsemblBacteria" id="ABX02718">
        <property type="protein sequence ID" value="ABX02718"/>
        <property type="gene ID" value="Haur_0066"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0066"/>
    <dbReference type="HOGENOM" id="CLU_1956587_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-67-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14320" checksum="0CCCAA9AA73FFF7E" modified="2008-01-15" version="1">MTTSTDIYSVVRETLRANSLHNAGTLPPPRLHTIAMQIGQFLLDEQPTSATLMGRMLFQQGIGLKSLLAVVGAVQADYLRHGEQLRAIESYELLKVVIESFVEHQIAHVRSEHDRFRQTVGLLQRSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G2</accession>
    <name>A9B4G2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0067"/>
    <dbReference type="EnsemblBacteria" id="ABX02719">
        <property type="protein sequence ID" value="ABX02719"/>
        <property type="gene ID" value="Haur_0067"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0067"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_0"/>
    <dbReference type="OMA" id="RAMEFMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-68-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="29435" checksum="94007FFDAEF32599" modified="2008-01-15" version="1">MEFDPSQPNAGRIYDYLLGGSHNFAVDRMAAERLVQMIPTIENGARLNRWFLDIAVNRLADLGFNRYLDLASGLPTQGYIHEIRPDALVLYNDYDQATVAYAREIIGNNPRVIYHQANIAELESILAQAEQHFAGERKLAICMIGVSYFLNDQVLSQTLQRLYEWCAPGSQIAISWIALPENPNPKLQELLARYSAMGSPIYARTVEQIKQFIAPWTLLEPGFQRLSEWNEIDGTWVIDGDRQEGDEQSDMYGTFMIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G9</accession>
    <name>A9B4G9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0074"/>
    <dbReference type="EnsemblBacteria" id="ABX02726">
        <property type="protein sequence ID" value="ABX02726"/>
        <property type="gene ID" value="Haur_0074"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0074"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_0"/>
    <dbReference type="OMA" id="YPIPEPF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-75-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="315" mass="35273" checksum="BB7E6A57D41DF6FB" modified="2008-01-15" version="1">MLVKQLADYMRQEAAKVIVGQEDTWTQLVVALLSGGHVLLEGVPGTAKTLMAKTLAHLVQAEFKRVQFTPDLMPSDVMGTSVYEMQTSQFRLRKGPIFTQILLGDEINRAPAKTQAALLEAMEEQQVTIDGDTMPLPQPFFVIATQNPMEYEGTYPLPEAQLDRFLFKVLVGYSPPEIEFEVLRRYNQGFSARNLSTANLQPTVTPETIMRCREEIGRLRVEDGVINYINAIAQESRRSPDLVLGGSPRASIALLLTAKTFAAMQGREYVVPDDVKFLARPVYRHRIILKPEAEIEGLTPDTAMTRILGRIEVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N1</accession>
    <name>A9B4N1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-dehydroquinate synthase</fullName>
            <ecNumber evidence="4">4.2.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1553"/>
    <dbReference type="EnsemblBacteria" id="ABX04196">
        <property type="protein sequence ID" value="ABX04196"/>
        <property type="gene ID" value="Haur_1553"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1553"/>
    <dbReference type="eggNOG" id="COG0337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001201_0_4_0"/>
    <dbReference type="OMA" id="INRAGIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1577-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="3">
        <location>
            <begin position="81"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="42374" checksum="0AA9557600129002" modified="2008-01-15" version="1">MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNLLTEIAAYAQASQAFSLVEPSLILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGGALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSINAFGKKNFLGTFAPPYAVLNDSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAELHLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADLAEADWQRVLTCLTAVGFELYHPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGIGQPYDVHTIDLPMMQQAIRYLAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S7</accession>
    <name>A9B4S7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3012"/>
    <dbReference type="EnsemblBacteria" id="ABX05650">
        <property type="protein sequence ID" value="ABX05650"/>
        <property type="gene ID" value="Haur_3012"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3012"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_7_1_0"/>
    <dbReference type="OMA" id="CGLFTPR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3044-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="4"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="245" mass="27593" checksum="205AE8FF94B718A1" modified="2008-01-15" version="1">MSRILVVAKRVLTQLRHDKRLLGLSVMAPLLIIYLLKIFFDTMPKGFNNARYIMPITAFMVHFLAFLLCAIVLVQERTAGTLERMFINGFRRIEIIGGYVLGYILLATFQAAIALAQALWLFDLSYAWGDLAMLFGVIWLLAITSVMLGMFISTFARHEGQVFPFIPMIILPSVFLSGLLINPEQLPTWANWLGHAFPLFYANDAIQEIIGKTPTSSVIWTNMAILVGYGLFLLTLASRTLKDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5E2</accession>
    <name>A9B5E2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0115"/>
    <dbReference type="EnsemblBacteria" id="ABX02767">
        <property type="protein sequence ID" value="ABX02767"/>
        <property type="gene ID" value="Haur_0115"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0115"/>
    <dbReference type="eggNOG" id="COG2317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032916_1_1_0"/>
    <dbReference type="OMA" id="THHPFMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-116-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="501" mass="56514" checksum="4471FE59ECB9ED0C" modified="2008-01-15" version="1">MQEQLADLKEKIGVAQDLSYASAVLNWDQSTYMPAGGAEARGRQMATLSRLAHEHSTAPEVGRLLEQLVPWAEQQDPESDDAALVLVTKRDYDQAVRVPSEFIAELYSHVAKTYTAWTQARPNNDFASVAPLLEKTLDLSRRYAEFFGPSEHIADPLIDMADQGMTVAKIREIFGPLREQLVPLVKTITEQPAADDSCLLQHYPEAEQLAFGESLIREIGYDFERGRQDKTHHPFMTKFSIGDVRITTRFRENDLSDGLFSTIHETGHAVYELGVNPAYENTPLASGASAGTHESQSRLWENVVGRSRAFWQYAYPKAQAAFPNQLGKVDLDTFYRAINKVQRSLIRTDSDEVTYNLHVMIRFDLELALLEGKLAIRDLPEAWHERYRSDLGITAPDNRDGVLQDVHWYGGIIGGSFQGYTLGNILSAQVFDAAVRANPNIPTEISQGQFANLHNWLKSNMYVHGRKYSVPTLIRKVTGQDLSIEPYIRYLRTKYGELYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H7</accession>
    <name>A9B5H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0150"/>
    <dbReference type="EnsemblBacteria" id="ABX02802">
        <property type="protein sequence ID" value="ABX02802"/>
        <property type="gene ID" value="Haur_0150"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0150"/>
    <dbReference type="eggNOG" id="COG3440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1238796_0_0_0"/>
    <dbReference type="OMA" id="HNIADAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-153-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="127"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="25692" checksum="0CFF923A7FEB07B7" modified="2008-01-15" version="1">MAMIKKEIKPVTGNFLNNFWGIGAKHALYHKDGNWYHQLKKFPGVLFDAHGYILFETDDEFFNSPSLRIRKDVRVPQGIASIKEYIKLSKNLPIETISRIKVNNKPAGNRLTRRTINTIDRIQRDTKVSSWVKYIYNYACQICGIRLQIGQDKFYAECHHIRPLGGVHQGEDIVENVLCVCPNHHALLDYGAIRIDFSTLHSHPNHLIDPESVDYHNNNLSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M2</accession>
    <name>A9B5M2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1612</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1612"/>
    <dbReference type="EnsemblBacteria" id="ABX04255">
        <property type="protein sequence ID" value="ABX04255"/>
        <property type="gene ID" value="Haur_1612"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1612"/>
    <dbReference type="eggNOG" id="COG3407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040369_0_0_0"/>
    <dbReference type="OMA" id="LTLHAMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1636-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="8">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="MDD_C" evidence="9">
        <location>
            <begin position="187"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="36162" checksum="E64CF375089C79AF" modified="2008-01-15" version="1">MKQLSHAATAVACANIAFIKYWGQHDSQLTLPTNGSISMNLDGCLTETTVQCLPEAVDDSVWLALSGGEEVQAKGRQFERVIQQIERLRQLAGVTERVEVRSRNNFPSDAGIASSAAAFAALTRAAASAFRLELDEAELSRLTRLSGSGSACRSIPAGFVEWYNDGTHAGSYAAQIAPPEHWNLVDIVAVISTEAKHVASTSGHSVATTSPYFSVRLEGIEQRLADVRQGILERDIERLGRASEADAMSMHVIAMTAQPSTMYWLPGTLAVMQAVQRWRAQDNLQSYWTIDAGPNVHVICEAKDAPEVEARLCELDAVQWTIVNGAGPEARLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P1</accession>
    <name>A9B5P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1631"/>
    <dbReference type="EnsemblBacteria" id="ABX04274">
        <property type="protein sequence ID" value="ABX04274"/>
        <property type="gene ID" value="Haur_1631"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1631"/>
    <dbReference type="HOGENOM" id="CLU_2316444_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1655-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="10616" checksum="A40BA929EAE71AD9" modified="2008-01-15" version="1">MLAWLGFLGLLGFGWVAVASLRGAMQGRASMLWLLGAWTGLSALGGLLVWRAALLETWSFSLWIGLALAAIAPIAWTLGNVGKRLQAHGIKLGNLLKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X8</accession>
    <name>A9B5X8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PT repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3134"/>
    <dbReference type="EnsemblBacteria" id="ABX05771">
        <property type="protein sequence ID" value="ABX05771"/>
        <property type="gene ID" value="Haur_3134"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3134"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045984_0_0_0"/>
    <dbReference type="OMA" id="PGKTWIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3166-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735479" evidence="2">
        <location>
            <begin position="21"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048" evidence="3">
        <location>
            <begin position="67"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="4">
        <location>
            <begin position="252"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="371" mass="40200" checksum="5532C43C6299B884" modified="2008-01-15" version="1">MRRWFSISLLLLLVACSTTGAPTATVPAQPSPTATTQPSPTTAPTATTQPSPTIEPTATPISSDPRTGRPAMARGTLTQRPYITMIDNFPAAYPQTGLDQAAIVFEALAEYGVTRYMAVFTPDLAEVAGDLGPIRSARLYFVQWAMGFRAVYTHAGGSPEGLERLAADANDLVIDIDLVSLESRQIFDYSRRSLAREAPHNLYTSAAEIAQYVDDRASSSAQADVSEVGYLFAPEAAIAEPISTIDYFFIYPEDPAGWRYDADTNEYARLRRGTAHIDAVSGEQLTFKSIVTMEVVEAPIIGDDKGRIDQQVIGEGRALVFANGSLQEATWRKDSESAPLRFYAANAAEIVFPAGPIWIAAMPSLDNVSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z8</accession>
    <name>A9B5Z8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05791">
        <property type="protein sequence ID" value="ABX05791"/>
        <property type="gene ID" value="Haur_3154"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3154"/>
    <dbReference type="HOGENOM" id="CLU_1093139_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3186-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="27989" checksum="89AF6A3AA757836F" modified="2008-01-15" version="1">MNDLQIAEQLQASYILFAPIRAHFRGPGVERGGCPRHGMHAVYAKKYGEHLATIYPGINAIGVESSFDAAQLPAIMAALASLREVLLPNLAHRIVEYAQASKPYVLPAYLRSIEVALEHFAKRHPEQLAALDAVFCVAGGEGFRDLIVFHGGHLLEQAKAGALWTNIDIYSLVDLHDRQTAEGLEKFEVWCLGGDLAKAVLTEFQKAALMLVIQGWQPQPLTKELALLPADLNRHFGQMLRNLLHKALAQYVLG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J1</accession>
    <name>RPOC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="1">RNAP subunit beta'</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoC</name>
        <name type="ordered locus">Haur_0242</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B6J1"/>
    <dbReference type="SMR" id="A9B6J1"/>
    <dbReference type="STRING" id="316274.Haur_0242"/>
    <dbReference type="PRIDE" id="A9B6J1"/>
    <dbReference type="EnsemblBacteria" id="ABX02894">
        <property type="protein sequence ID" value="ABX02894"/>
        <property type="gene ID" value="Haur_0242"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0242"/>
    <dbReference type="eggNOG" id="COG0086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_3_1_0"/>
    <dbReference type="OMA" id="YRNIRVE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000141772" description="DNA-directed RNA polymerase subunit beta'">
        <location>
            <begin position="1"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1466"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1522"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
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        <location>
            <position position="78"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="629"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        <location>
            <position position="631"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="1017"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
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        <location>
            <position position="1097"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
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        <location>
            <position position="1104"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
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        <location>
            <position position="1107"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="1543" mass="172905" checksum="380414A46E84E470" modified="2008-01-15" version="1">MLEINEFNAIRISLASPEDILSWSHGEVTKPETINYRTLRPERDGLFCEKIFGPTRDWECYCGKYKRVRYKGIVCDKCGVEVTRSKVRRDRMGHIKLASPVSHIWFVKGTPSRLGLLLDISPRNLERVLYFASYIITDVDDLALGNVREQMKTDFGVRRKDLEEKIIEQRGEKATRLSKDLAAMDNAMEGTLERTHEQFARQRQEIEDEANALREHLEELIGIDALADEDIVYRGTVLLEENEPVRERSLEQLEQLIDQEREKLEQRREYEIENVRLLADGERDQRQSVADAEQERLTTALIKQLEDLNKEEKDKLDRLDDIQLHRIISENEYRILRDLAPYTFKADMGAGAVRDIVSMVDLDELSNQMQAEVQSSSGQRRKKATKRLRVVEAFRKSGNRPEWMIMTVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLMELNAPEIIVRNEKRMLQEAVDALIDNGRRGRPVSGKGKHRLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPTLQLHQCGLPKKMALELFKPFVMRRLVDKGFAHNIKSAKRFVERVRPEVWDVLEEVIKDYLVLLNRAPSLHRLSIQAFEAKLIEGSAIQLHPLVCAAFNADFDGDQMAVHVPLSRKAQEEARRRMISTYNLLSPATGDPIITPSQDIVLGCFYLTQVRPGAKGGGKRFGSIDEALLAYTNGVVHIQAPVWIVIEDYILPGSDLREKELPSLDGVTPRVLIETSVGRIIFNNALRYQGEPKAGENGYRSPLHYRNFLVGKSGLKALIADCYRFHSQRENIIADVYQELIERFGPETSEESLLRFYASERTARLADRIKALGFKHATLGGMTFSASDVEVPDTKDAIVQETYKKVQDIEKMQRRGLITDDERYREVVTAWLDATNQIKVEVQRSLNPFGPVSMMSTSGARGNVEQIRQMAGMRGLTTDPTGRIIELPITANFREGLSVIEYFISTHGGRKGLADTALRTADAGYLTRRLVDVAQDVIVTIEDCGTTEGMWIRVSRDILASVEDRIVGRVTVAPVTNPVTGEVIFDTDSEILEDDGKHIANVLKSLDKEAQAEFGIYVRSVLTCNADYGICRKCYGRNLATGKMVEIGEAVGIIAAQSIGEPGTQLTLRTFHTGGVATDTDITQGLPRVQEIFEARIPKGKAVLAQIAGRVQIVREEEGIRRLRIVSEEVYTDEQMLPKDYRVVVKNGDAVEIGNLLAESNVDGDGRAPLVAGLAGNVYVDDDRLVIQAKDIEEHEEVIAHAARLRVKDGDLVQVGQQMTEGSSDPQEMLQLRGREAVQEYLTNEAQKVYRSQGVGINDKHIEVIVRQMLRRVRIEEPGDTELLPGELVELHELNRINASIVSQGGDPALAVPVLLGITKASLSTDSFLSAASFQETTRVLTEAAVNGKIDYLRGLKENVVIGKLIPAGTGMEQRRKLAEEAALRVAQITSTPADREVPAATPAPAVMSEPKPAPPRSFDEALNAVTNIDSGNGPKDDLFAQAMARLQAEEGRKPTLSELLGTDEDEENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J4</accession>
    <name>A9B6J4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_0245</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0245"/>
    <dbReference type="EnsemblBacteria" id="ABX02897">
        <property type="protein sequence ID" value="ABX02897"/>
        <property type="gene ID" value="Haur_0245"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0245"/>
    <dbReference type="eggNOG" id="COG0196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048437_0_2_0"/>
    <dbReference type="OMA" id="HRGHQAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-248-MON"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="186"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX02897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="35105" checksum="ECB89BF152D9EDE7" modified="2008-01-15" version="1">MNWNQAMHFAELASVHYQTPTLLTIGKFDGVHQAHQQLLRRLVERARQHNCHSAVLTFDPHPDEILRPEREIRYLTTINERAALMQELGIDLLAVLPFTHATSQLSPKAFLQLLLNHVPVRELWVGPDFKLGHRGTGTIPVLQEFGQELGFTVEPIPYWTLDGEIVSSTAIRTSLAAGDVQTANHYLGRAFSLQGTVIPGDQRGRKIGFPTANVQIASNHTLPADGVYVCKVQLLDDRRSFGAVTNIGVRPTFGVLGRAVEAHLFDFNEDIYGRPLRVSFLQHIRGEQKFAGIEQLVAQIGRDAQFAREWLANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L7</accession>
    <name>A9B6L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1683"/>
    <dbReference type="EnsemblBacteria" id="ABX04326">
        <property type="protein sequence ID" value="ABX04326"/>
        <property type="gene ID" value="Haur_1683"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1683"/>
    <dbReference type="eggNOG" id="COG4989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_8_1_0"/>
    <dbReference type="OMA" id="VVYAWVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1707-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="18"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="36284" checksum="024A5A9BF80939C8" modified="2008-01-15" version="1">MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDHADIYTRGKSERLFGELLAEQPSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVEGSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGKVRYFGVSNHSPAQIDLIQAALDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQLVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAATKQALQIELSREEWYHLLAAARTANVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R7</accession>
    <name>A9B6R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate dehydrogenase or fumarate reductase, flavoprotein subunit</fullName>
            <ecNumber evidence="6">1.3.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.3.99.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1733"/>
    <dbReference type="EnsemblBacteria" id="ABX04376">
        <property type="protein sequence ID" value="ABX04376"/>
        <property type="gene ID" value="Haur_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1733"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_7_0_0"/>
    <dbReference type="OMA" id="DPIPIQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1760-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="36"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="502"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="637" mass="70796" checksum="7A2FD57A651A97E7" modified="2008-01-15" version="1">MQLNAKIPAGPLEDKWDQHRFNVKLVNPANKRKYTVLVVGSGLAGASAAASLAELGYNVKCFCFQDSPRRAHSIAAQGGINAAKNYQNDGDSVRRLFYDTIKGGDYRAREGNVYRLAQVSVNIIDQCVAQGVPFAREYGGVMANRSFGGAQVSRTFYARGQTGQQLLIGAYSALERQIGLKKVAMYSRCEMLDIVLVDGKARGIITRDLINGKIERHAGDAVVLATGGYGNVFYLSTNAKGCNVTASYRAYKRGAAFANPCFTQIHPTCIPVAGDHQSKLTLMSESLRNDGRIWVPKKAGDNRAAKDIPESERDYYLERKYPSFGNLSPRDISSRAAKEVCDEGRGVGPGGLGVYLDFSDSIKRLGKNMIAERYGNLFEMYERITGENPYEVPMRIYPAVHYTMGGLWVDYNLMSNVEGLHVLGEANFSDHGANRLGASALMQGLADGYFILPYTIGDYIASAKLAPVSTDHPAFAETEREVTTRLKQLLEINGKRSVDDFHRELGKVMWDYCGMARNDAGLRTALERIPQIREEFWRDLRVPGSGEYFNQELEKAGRVADFLEFAELMCHDALMRTESCGGHFRTESQTEDGEAKRDDENFTFVAAWEYKGVGTKPTMHKEVLEFENVHLSTRSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6V0</accession>
    <name>A9B6V0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1766"/>
    <dbReference type="EnsemblBacteria" id="ABX04409">
        <property type="protein sequence ID" value="ABX04409"/>
        <property type="gene ID" value="Haur_1766"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1766"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_21_0_0"/>
    <dbReference type="OMA" id="LELWSQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1794-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013663">
        <property type="entry name" value="Helicase_SWF/SNF/SWI_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08455">
        <property type="entry name" value="SNF2_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="608"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="890"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1055" mass="119930" checksum="0148EC3D745E0897" modified="2008-01-15" version="1">MLAADLLNISALRAEAGQRVVQAGEAYYRAGQVEMLDLDHDQALFAVHGSQENPYTVTIISDQHWLISDCTCPYAAKGVICKHVVAAALYLYDQLVAHPPSIWRSIFANIQPPTRRRQNSMLLIFSLIERGASWTLVPYTFAERVIPQPVMHDPVALHKHLNTSAMLKHAKIPHTQLQPQQFPHSPEAALTLANMIVAFSQNYFYGITLQLPIILNALVQLLPDAAIFCGDDLHPFQRTLQVAVNRGQIQLHGTATTDGMTLTPMLRFGETSTNLDTDEVRILLFNAEWAIYRDWLVRYDDPGNILSLFRRHNHLNIPAADHTEFIEQYLVPLAEHTALSGDLPHQELVVADPQPRLYLSDHESTLRAELRFGYADHELVYDLQLPAETIRYSHEHATILRIQRQPSIEEQCWGELMRHGLKRGQQPSVATLRSGTTSATFLLNHVPKLAAMNFTIYGEESLLGARVNRHTPSITLRVSSGIDWFDLEAVVRFGETELELAELRRAIRKRKRYVKLADGTLGAIPELWLERYRHLFTLGEMHAETLRFAPTQITLLDGLLHNTDQVDPTFKQRLQGLKTINGIAPQPLPSGFAGVLRSYQKAGYDWLHFLYKYGFGGCLADDMGTGKTIQTLAFLQSLKARGQASASSLIVMPRSLIFNWQREIARWTPDLQVLVHTDQGRPDTVAAFSDYDLVLTTYGTLLRDIDLFATYQFHCLVLDEAQAIKNPSSQTARAARALHADHRLTLTGTPVENSILELWSQFAFLNPSMLGSLEHFRSEFATPIERDGDQQTAQLLRRMVNPFILRRTKDQVAPELPPRNERLMYCDMEPAQQKLYQRYRDQYRAMLLSLIDDQGINDSRIKVLEGLLRLRQICNHPQLVEATFRGHSAKFDQLLETLEVLHAEGHKALIFSQFVQMLTLLWKELDRRNLSYAYLDGKTNNRAAVVDRFQTDPQIHFFLISLKAGGVGLNLTAADYVIHIDPWWNPAVEQQATDRTHRIGQDKPVFIYKLIVRNSVEEKILQLQERKRALANNIITSEQGIVKSLTREDVVDLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z1</accession>
    <name>A9B6Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3222"/>
    <dbReference type="EnsemblBacteria" id="ABX05859">
        <property type="protein sequence ID" value="ABX05859"/>
        <property type="gene ID" value="Haur_3222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3222"/>
    <dbReference type="eggNOG" id="ENOG5032ZRZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132548_3_0_0"/>
    <dbReference type="OMA" id="RAQWVRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3257-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="13542" checksum="38CD323670E2F30D" modified="2008-01-15" version="1">MATEERMRILRLIENGQLTAEEGARLLGVMEPNNRVSRPPRAQWVRIRVTDLKSNHHKINVNIPVGLISIGLKLGARFASNKHTTLNFDEMLEAIRGGMTGKIVDMEDLEDGERIEIVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B719</accession>
    <name>A9B719_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3250"/>
    <dbReference type="EnsemblBacteria" id="ABX05887">
        <property type="protein sequence ID" value="ABX05887"/>
        <property type="gene ID" value="Haur_3250"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3250"/>
    <dbReference type="HOGENOM" id="CLU_1029633_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3285-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="29647" checksum="A3BB506C52C535C9" modified="2008-01-15" version="1">MAQTRELTYPLQFSTPQLAYLLGMVHAQNLIGGDDAALFPADPDQRQAQWDQGLAELQADQWIVWDETAGHYSMTEPLMMVIATLAEPDIVVVSEWHAHHSGHQGVSHYFSPSGIIEMSLVGSHYTLVALTNTEVMTERLAHSLGYKELDQPDLGFNFPRELVEQAKQYPDPRWLAQQGLAPEAAQYFAETLQATASRGTVTVLRTLEGKAIGMRLVGALIGAGGQQWLALPHPNQTIDYFTATTANFMGVTSSMISELLNTPIEELVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B778</accession>
    <name>A9B778_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3725</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06361">
        <property type="protein sequence ID" value="ABX06361"/>
        <property type="gene ID" value="Haur_3725"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3725"/>
    <dbReference type="eggNOG" id="COG1496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065784_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3767-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="31042" checksum="63F22A64EDBDDECE" modified="2008-01-15" version="1">MLNVPSVASSSLDPEVASPIVRVSGLVGLPFLQHGFSTRTCGNLATRYGPPAEVGAARRTFARVAGIDAGRVAHFALTHSSRVGLVSDPDSMPIDSTPHRISVRGLLADASPRDLSFINAQGIPNQQGVDSLITTTRNLALFMVVGDAAPVIITTRQGKAVALVNVGLVGTVNNVLENTIEALCHLVACQPSDLVVGIGPTVGPCCYALAQSLTWAQVVSPAFFQRHGPNAPGIIIRDEQYFFDLPRMIGHILEQTGVQTSNIHSIDLCTACPDTAFFGHYAGVAGRFGALVALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D0</accession>
    <name>A9B7D0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3777"/>
    <dbReference type="EnsemblBacteria" id="ABX06413">
        <property type="protein sequence ID" value="ABX06413"/>
        <property type="gene ID" value="Haur_3777"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3777"/>
    <dbReference type="eggNOG" id="COG4895">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182218_0_0_0"/>
    <dbReference type="OMA" id="PHGIKVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3819-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="PTHR40069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03833">
        <property type="entry name" value="TIGR03833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="68" mass="7181" checksum="153BC59D3EE85FF3" modified="2008-01-15" version="1">MNGQQRSAIKPGIQVAIVLKQDQATGKTTTGIVKDILTKSPNHPHGIKVRLVTGEVGRVKQILGSPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M8</accession>
    <name>A9B7M8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0350"/>
    <dbReference type="EnsemblBacteria" id="ABX03001">
        <property type="protein sequence ID" value="ABX03001"/>
        <property type="gene ID" value="Haur_0350"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0350"/>
    <dbReference type="eggNOG" id="COG1732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038355_1_0_0"/>
    <dbReference type="OMA" id="KDPAWKN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-353-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734619" evidence="2">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="46"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="34162" checksum="46C5AC7A3D301ECB" modified="2008-01-15" version="1">MRRFIQLTVLLTLLMTILAACGDDAASSTTAPSSDPNPAPSSNQVIRIASKNFTEQFIVGEMYALLLEQAGYKVERKIGLGATDVAQAAMEKGEIDIYPEYTGTGLLTVLKLPTQTDPKAVYETVKKGYAEKYQIAWLDPAPMNNTQALAMTKEGAQKFGIITISDMAAKAGELRMIGPPEFQEREDGLPGIQAKYGNFELKEYVPVDPGLKYKGLVEGNADVVVAFGTDGEIANYGLVVLKDDRNMFPPYQIAPLVRQSVLDANPKLAELLNALAPKLDDATMQQLNFEVSGNNRKYEDVAKEFLTTQGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X8</accession>
    <name>A9B7X8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-(2-amino-2-carboxyethyl)-L-glutamate synthase</fullName>
            <ecNumber evidence="5">2.5.1.140</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1863</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.140" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1863"/>
    <dbReference type="EnsemblBacteria" id="ABX04506">
        <property type="protein sequence ID" value="ABX04506"/>
        <property type="gene ID" value="Haur_1863"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1863"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_0"/>
    <dbReference type="OMA" id="GSWCPDQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1892-MON"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023927">
        <property type="entry name" value="SbnA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03945">
        <property type="entry name" value="PLP_SbnA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="18"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="36786" checksum="5599EB6788887C67" modified="2008-01-15" version="1">MLTHGFTKLARSHDGIVQLIGNTPLIPLRRIFAEHPIQLFAKLEMFNPGGSVKDRVARSIITKALAEGRIDQATTIIESSSGNLGIGLAQVCRYFGLRFICIVDSRTTNQNIQILRAYGAEVEIITQPDPDLLTARIKRVHALQASIPNSFWCNQYANLHNPMAHYATMSEILASLPNVPDYLFCATSSCGTLRGCAEYIREQGLATKVIAVDALGSVIFGGQPGQRLIPGHGASRIPELFQPDLAAGVVYVSDADCVAGCHSLLDQEAIFAGGSSGGVIRAIAQMLPSMPANATCVAILCDRGERYLDTVFNHAWIDQHLPSVLINQSQPLIERENVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z2</accession>
    <name>A9B7Z2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3288"/>
    <dbReference type="EnsemblBacteria" id="ABX05925">
        <property type="protein sequence ID" value="ABX05925"/>
        <property type="gene ID" value="Haur_3288"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3288"/>
    <dbReference type="HOGENOM" id="CLU_2206407_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3325-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="11752" checksum="0F46170F0360EA9B" modified="2008-01-15" version="1">MTWLSTIVLLLIPLVLAPCQPRILISYHYPCAAQVDQGFNDEHHAEQPISTPAESPSDACVSHAAPFLSVSAQFELILVADQLHWMPDPLNYRSPSLALLVPPPKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B802</accession>
    <name>A9B802_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3299"/>
    <dbReference type="EnsemblBacteria" id="ABX05935">
        <property type="protein sequence ID" value="ABX05935"/>
        <property type="gene ID" value="Haur_3299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3299"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069789_0_0_0"/>
    <dbReference type="OMA" id="NDIRRLH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3336-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="103"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="36834" checksum="1921D1734440AEEB" modified="2008-01-15" version="1">MQVASTWRRSRWISLVVTSLLVFGLVAPLAAQEPQAIAGGSMNYLPAVMSNPELDINNRQSVVNFYTNFYLPSEGVADGWTGSQASCNAGTTSQAYRDAILLRVNYFRKMAGMAAVTLNESYNSQAQQAALMMSRNNSLSHSPPTSWACYTAAGKTAAGKSNLYLGQIGPGAITGYMLDPGAGNSAAGHRRWILYPQNKSIGTGDVPSRSGYAGSNALYVITSDFGTARPATRTEYVPWPPAGFVPYQVVFGRWSFALHNGNFSNATITMSQNGTNIPVTKETVATGFGENTIVWIPQGYNHSSSWAQPSADTTYTVTISNVVVNSQNRSFTYNVTVINPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B820</accession>
    <name>A9B820_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3317"/>
    <dbReference type="EnsemblBacteria" id="ABX05953">
        <property type="protein sequence ID" value="ABX05953"/>
        <property type="gene ID" value="Haur_3317"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3317"/>
    <dbReference type="HOGENOM" id="CLU_1553168_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3354-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="172" mass="19938" checksum="62063A57D3A0BFE1" modified="2008-01-15" version="1">MTKRTLGLLLIGAGIIALFSNIGNGLFGRDRYEYDREWNSEVAYAVSQGGEDFHENMADFEAEMSDLQAEMRDVQSEINETVGSNLRDSGAEFREEMANLREEMRDVQTEMRDAMPAAPWTEPQPHFQYEYHHRDGSPFGFLLFPLLLGGGIFLLVRRRRMVVRRHQEIHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B883</accession>
    <name>A9B883_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3800"/>
    <dbReference type="EnsemblBacteria" id="ABX06436">
        <property type="protein sequence ID" value="ABX06436"/>
        <property type="gene ID" value="Haur_3800"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3800"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_0_1_0"/>
    <dbReference type="OMA" id="VFFNFFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3842-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735369" evidence="7">
        <location>
            <begin position="25"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="343" mass="36872" checksum="1844BC7C37AA172F" modified="2008-01-15" version="1">MQRLRPLLPLVAIGGLASLPFAFAADTTRFWQGVFIQIFILAIYALSYDLLMGYTGMISFGHALFFGAGGYTAAILLRQAEPPSMLIVIAAVIVVGATIGAAVGALSLRVSGVYFSMITLALAEIAFILFKADDPKLKPITGGEIGLQGIVVPAAIDATTYRLRFYFLTLACMVGLYYAARRLINSPTGRVFVAIRENEPRATALGYNTLHFKLLATAISSTIAALAGMLMVLYEKSASFEMLSVNLTIQALLMTIIGGIGTLIGPMLGAATIRLLDHGLKGEFMQALLPAWLRPDLVFGIVYVVLVLFFPAGLMGAIRKLRGKTSRSSVERLRQAMKPKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B889</accession>
    <name>A9B889_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3806"/>
    <dbReference type="EnsemblBacteria" id="ABX06442">
        <property type="protein sequence ID" value="ABX06442"/>
        <property type="gene ID" value="Haur_3806"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3806"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_648555_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3848-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="275"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="48135" checksum="5E236A53B0005E51" modified="2008-01-15" version="1">MQQVVRVFHQLLPDFVDHVSEQIVANHVPVYASLPQQHVKMALYNAIHSIEIDLAQGTTSTYADYWREVAVQRAQQGISPVHSMLVTHLSTNVMTQFLKQALDREPEALAWWLERTHTIISLGMLVMTEARINALQQLGQLGSEPASSGIIIHEQPNLILPPSRWQTPQVLHLQAFGQMRAWRGSSEVLNWGRKSAIALLGILITQRGQWIQREQICDLFWPDLAPNQAEAHFKVALNALTAVLEPERPTRQASSYIQRRNTAYRLAFDTAPIQLDVLRFEQLLQRANHASNPLEAINYYRQALNLYAGDFLGDCLYSDWANAVREQLRHHFVQAACELAQLLLAEQQPTEALEWAEAALQADPYQENAYQASFMAYAQLGNRVQLQRSYQRCQQVLEHDLGLAPMPTTKAAYQRAEQTLHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G5</accession>
    <name>A9B8G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07629">
        <property type="protein sequence ID" value="ABX07629"/>
        <property type="gene ID" value="Haur_4999"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4999"/>
    <dbReference type="HOGENOM" id="CLU_350830_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5062-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="802" mass="89140" checksum="6E7C356D97A7259D" modified="2008-01-15" version="1">MNSPREPHACGHPVGDGRRRAFSLLTGVPAMTTPTTKPAFTTIVAGPIHLVGTSEQVAAYYTHGTGDLPPWWAEWDQLLGDTWAMDILESPSDVSRFMRAAEVHPTLPRVGFISNSKLKLESGYVLGAEDRDYKNTAQRLHRYWQSLPEAMQQRYARFGSPATIAGLLMRREEWVDSRWGSSVHEADTRSALAKQAKATTEGRIAADASAPDRPNQRAIPLMRYGGLACPRCGWLQRKTDGAVLDAKQLKQRGLASVTCPQCHDHLGQQCRERDNVQDRSLPIFQSDDWQTYAVDANGRRAIPWGQRPRSNPRMALASFIQRRYPQRVDLYVHDEIHEAKGARTALGNAFGAMVAASRTTVGMTGTAYGGMASTLYDLLLRLGNTVIRDRWGWNNRSAFVRDVGVVDVMDKEITRAATAGHYDGKTRTSTEVQERAGITADLITIVQNCTYTVLLKDMGFQLPDYREDVVLLKLPMDMQAQYRQIEDEGKAIIGNGGYDALSAYLQATLSWPYQPWRPKTISSQLVNETVRTPELPAERILPHHTWLAQYCAAQIQQGRRVLLFAEHTGNDDIAVDLAEKVTALAHEQHQTTLKVAILRATTVAPGERNAWFTEQVNNGANVVVCNPRLVKTGLNLIAWPSIVVVEPLYSLYDLFQAKRRAFRPTQTMGCEVTFLGYEHTMSHRALGVVGRKAAAATMLSGDDSEGGMLEFDPGMSLLQELAKQLRNANPMDDARALRDQFRSVGQTLKAEAERPSLILPTDPTPPPSDTAAQPIRWDELFTVVDVPTRHTAQVAHQFAMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J4</accession>
    <name>A9B8J4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07658">
        <property type="protein sequence ID" value="ABX07658"/>
        <property type="gene ID" value="Haur_5028"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5028"/>
    <dbReference type="HOGENOM" id="CLU_108780_1_0_0"/>
    <dbReference type="OMA" id="LMANKYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5091-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="42"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23191" checksum="F4D80EFD78A36F48" modified="2008-01-15" version="1">MPKTANYKAGDVVVNPITGERGVVRLGASESHDGSGVYDLYVQPGGAVAGEHIHPNMLESFTVLRGRVGFRIDGKESIVELGAKMTVPIGVAHDWWNVGDEEAHVLVEVYPAARFEEAITDLFGLARNGKTNTNGMPKLLQGALFAREYKDVLYFTKPPLWVQNILFAVLAPIAKLLGYQGSYPEYRTQPRGWVEVEPWPLTDKENGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q6</accession>
    <name>A9B8Q6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thymidylate kinase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07720">
        <property type="protein sequence ID" value="ABX07720"/>
        <property type="gene ID" value="Haur_5092"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5092"/>
    <dbReference type="HOGENOM" id="CLU_105014_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5154-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="26536" checksum="31E8B44DD8B1AA75" modified="2008-01-15" version="1">MASPSRSVTSAHRHRSPMIYITGSDGTGKTTQVHRLMEVLTAQGLPVIHRWLRFPFRLSGLLLVYARIRGLSWYEAHPYGRQGYWDFHASWLMQHVFPIVLWFDALSVAIQAVYWPISRGNIIVCERFVVDMLADLMVATQDFGLLKRWYARWFMRLLPARTLVILLDGDPVHIRQRRPDLAYDRVLSDRIRAVRIIAAQCGWPLIAADQSIDAIHQTICTFVEDCYVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S8</accession>
    <name>A9B8S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07742">
        <property type="protein sequence ID" value="ABX07742"/>
        <property type="gene ID" value="Haur_5114"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5114"/>
    <dbReference type="HOGENOM" id="CLU_2206409_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5176-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="11472" checksum="4BE820AAAAA282E9" modified="2008-01-15" version="1">MDVFAPNAAGIGIACAVLSLHEVLECQEYGVLPRTEGMHCLRVADLDVIVHLAHGCATATPASTTPLGMWLGFPTLLAHTLYQAKQRRASGGIWYSIPLTLTAEALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T2</accession>
    <name>A9B8T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07746">
        <property type="protein sequence ID" value="ABX07746"/>
        <property type="gene ID" value="Haur_5118"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5118"/>
    <dbReference type="HOGENOM" id="CLU_660177_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5180-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="416" mass="45546" checksum="563F5BB28172751A" modified="2008-01-15" version="1">MTAHMLPSRRRRSPFARIGGRMVENDGFNENGVPEENSNLAEATPDVASAPMTAAPMAELPPITAVIPRAVTAIVEPVAQPMLEIPAVPVQPVVVNPAAPVQPDRQRVESITLRPTEPSTPPAVGLAAPLVQPERPRYAGPRVPRARLTSQAFAPHADRWGTNHMTVVGRATNDPVTVVRPTAGGAFNRYTVAIYDQVHGHDDVLPQISTVVMLVPRDAASLNLAFQPGRMLTVSGRLVVRTHFDGRYARTSEFGGLFQTQPYVLVGSAALTRGDASRQQYLIGQLSGTVTGVLKEPTSRFRFDRQHEQVVLMRVTEAFDRPPPARGQRIEHQIVPLLVPLAVAETLPQLTTGMRIQSEVELHVRHRILGNHHFALTGVPDEAKSQLRHRERWTLVATWMEEQTVCPPASDSSDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X1</accession>
    <name>A9B8X1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07785">
        <property type="protein sequence ID" value="ABX07785"/>
        <property type="gene ID" value="Haur_5157"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5157"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_15_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19816" checksum="1BCA9FF7D91AA7D2" modified="2008-01-15" version="1">MVLGRQGQYVDAERIYAELGVLLETRVGRDHPDVALNLNNHAIAQVAQGKYGEAQAMMERAVAICDQVWDVPHSATALSLTNLSMTLLYQERYSEAQPLLERAITIYERVHGPMHPDIAVPISNLAGVLEIQGRYGEAQSWIDQAVAVRETTLGADHPATRQTRAQRTRLMMKLWAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B960</accession>
    <name>A9B960_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5247"/>
    <dbReference type="EnsemblBacteria" id="ABX07874">
        <property type="protein sequence ID" value="ABX07874"/>
        <property type="gene ID" value="Haur_5247"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5247"/>
    <dbReference type="HOGENOM" id="CLU_1233657_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5309-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24205" checksum="FD6D28F30237582C" modified="2008-01-15" version="1">MKLILFIVFATLTPVVAGRGDLTLLIRDPSGQPIPQLTVLVFHDTDDAGRVLVTTGTTDATGRIMLPELAWGLYIVQFQGAGIQVPEQQNMGLLDDGGGVSNGFGVRFAEAARTERFVLTPMNGETTLVPLFDMAERDDAPPQPYDPLLAMIGVPTPTPFLLRDVVEGRVDASGQPIRARFDAGCLIGIGLLLWGMALIAFLGWWRLRRPRPPTKEANDAGLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B977</accession>
    <name>A9B977_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5264</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5264"/>
    <dbReference type="EnsemblBacteria" id="ABX07891">
        <property type="protein sequence ID" value="ABX07891"/>
        <property type="gene ID" value="Haur_5264"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5264"/>
    <dbReference type="eggNOG" id="COG1236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_341543_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5326-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="58"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="3">
        <location>
            <begin position="290"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="830" mass="89734" checksum="310C6A9838D0EFA0" modified="2008-01-15" version="1">MVVAGIFGTKMLSPQPPQTHATIARSNHLCNHRHADQTREELPRMISFHPFGGAQEVGASCGILKLGMRHILVDAGMRPAARPGQSRTPDLEALKGFPLDAILITHAHIDHTGCLPLVASLFPTVPIYATESTIALMRILLLDSARIMEQEHLAHELETPLYDQAMVTETLARIIPVAFHQELRPVAANQEISVTYLPAGHILGAGMLHITSPWGSILHTGDISVGHHRTITGVDLNTLPQVDMMICEGTYGNRSHKSRKDQEQNVVATIQQVIGHGGRVLIPAFAVGRAQELILILKAFRTSGVVSPVTIYVDGMCKAVCESYQQQSHDLHPALQKFLANSQRPLFVDPSFGVLAVHQGMRPRVIQSDEPAIIISTSGMLTGGPAPLYATKLAQDPRNAIIFTGYQDEESPGAAMLKATQGGTITLNGQRVTLGCPVYRYGLSGHADLGQLEQVIRLVQPQQLVLVHGDHDALSHLAARFKKLAVAIPAAGDVVTLTRRAPTVSLQAGQRLDMPTALPVAVEVVADPTPLKPAPTLADLYAIATANGIPARPWTAIELGAAWYGTAYQPTLRPIVEGVLSVARSHFRTKRLGSQTVFTPRPVLESGEPNVAAPPKPQPDDRWDVVPIGQIVLVLGSAAPPDRVQLGLITGEPTGSTVPLVVEAWKSPSQVRDTIHGVTPMSKPEWVGLEHAEIQANLKALRATVDAIPIDVLKLWQAQQGQPARLETLMASAPTLEEQVATGITLMRRGLLVWKREGVRWIPKPFESLNDQALITRHLDLITQVGATVTHIKDGRTGTLTGRGGWLQVEVRWDSGVVELVKDGLVRLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A6</accession>
    <name>A9B9A6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5293"/>
    <dbReference type="EnsemblBacteria" id="ABX07920">
        <property type="protein sequence ID" value="ABX07920"/>
        <property type="gene ID" value="Haur_5293"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5293"/>
    <dbReference type="eggNOG" id="ENOG502ZHGV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_936188_0_0_0"/>
    <dbReference type="OMA" id="WACAVSH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5355-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="34552" checksum="501BA25267C5AF67" modified="2008-01-15" version="1">MQLHTFRIGGTSMVHGGQVLRTLRLRLSDAQGKHISLERLADAAGISYEGLSNIERGRTKHPPRSKIMKILDALGSLCYPKESLRLQEKNNVLDAFGYEGLFSLPVPHEYTQTIEKWTLENKDSLIPSYLVDITQHILCWNTYSQKTSGIEIPAVEHHIYSLISKYTIFDIMFSKHFAPVRKNVLNQNIFFSLLLSTIKSELITHKHDQWYIDLIHDTSIKYPEFSTIWQDIKPMESSKTRFRFGPISINHKNTILNFEFQSFLFNDDIRFRTVQYLPCDTNTILIWNQWVSLQKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK8</accession>
    <name>A9AUK8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04535">
        <property type="protein sequence ID" value="ABX04535"/>
        <property type="gene ID" value="Haur_1892"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1892"/>
    <dbReference type="eggNOG" id="ENOG5032SZI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1914168_0_0_0"/>
    <dbReference type="OMA" id="IARNFRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1921-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14345" checksum="A68D43F7ECE33A0C" modified="2008-01-15" version="1">MRWIMHNMKWIMLVSGLLTCSMIMALINPQSALQSNFGETMNGPLVEVVVRNWGALITLIGILLLYGAWNVAQRPLILLIAGSSKLVFISLVLAQGSRYLGQQAGIAIAIDSVMVILFGIYLVGMRRGLAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUQ3</accession>
    <name>A9AUQ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA or RNA helicase of superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1937"/>
    <dbReference type="REBASE" id="16528">
        <property type="entry name" value="HauORF1937P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04580">
        <property type="protein sequence ID" value="ABX04580"/>
        <property type="gene ID" value="Haur_1937"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1937"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002151_1_1_0"/>
    <dbReference type="OMA" id="INIXSEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1966-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041635">
        <property type="entry name" value="Type_ISP_LLaBIII_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18135">
        <property type="entry name" value="Type_ISP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="284"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Type_ISP_C" evidence="2">
        <location>
            <begin position="659"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1024" mass="118324" checksum="499DCE35B1A183DF" modified="2008-01-15" version="1">MLSIKPNHKAVREYYASLRSLAEARAQHEGAVAPAFAALLRACASQMGWTLVEQYSIRLKKSSIRADGALLDSFTLIRGVWEAKDSNDDLATEVRKKFAAGYPAENILFQAPQRIILWQNQRQVLDVDISQPDALIDALLLFFNYQPPQYLQWDHAVVEFRERVPELAQGVLRLIEREISEKNQRFITALERFMALVREAINPNISVSAVEEMLIQHLLTERIFRKVFNNPDFVNRNVIAREIETVIQALTSRSFNRNDFLRELDRFYGAIESTAATIENFSHKQDFLNTVYENFFQGFSIKVADTHGIVYTPQPIVDFMVRSVEELLRREFNTSLGNAGVHVLDPFVGTGNFLLRVMHEIPRSKLRQKYAEELHCNEVMLLPYYIASMNIEHLYYELTNSYQEFNGICLVDTFELAQVGAGQQLGLFVPENTERVLKQQQQDIFVIIGNPPYNARQVNENDNNKNRKYEIIDQRVAMTYSRDSQQTNKNALNDPYVKSFRWAADRIIRNGDEGIVALVTNNSFIDDLSFDGMRKHLAQDFDAIYVLDLGGNVRKNPKLSGTTHNVFGIQVGVSIIFLIKKRGSTKASDAKIWYARAGEMWKKQEKFNLLNQAETIDKIEWQEILPDKKHTWLTDGLENDFDNFIPLGTKEAKKGFGQAIFTQFTNGVKSNRDAWVWNFDSDTLSNNIKTTIDYYNDHVSRWQRLVTKQEIDSFISTDDKKISWSGDLKSNIQRGRYIQYDANKVIDGIYRPYTKQKIYFERLLNERVYLIPSLFPTASENRVICVVNEAQIPFSAQITNVIPCLHYGGRQTQCFPYYVYDDDGSNQRENISDWALEHFRSQLGEPSIEKWDIFYYVYGLLHSPHYRERYAANLRRELPRIPIVALADFQALAQAGRELAELHINYESQPEYNLQWLENRDEPLNWRVESMKLSKDRTTLRYNNFLSLAGIPAAAFEYKLGNRSALDWVIDQYRVSTDARSGITNDPNRHDDPEYIVRLIGKIITISLKTVEIVTRIGDVALTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR6</accession>
    <name>A9AUR6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04593">
        <property type="protein sequence ID" value="ABX04593"/>
        <property type="gene ID" value="Haur_1950"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1950"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118025_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1979-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="17654" checksum="AEC30DFA6D1AAA16" modified="2008-01-15" version="1">MNLVIRQYADHDRAAVVDLSIRAWTLVFASMEAAMDAAVFKHFYPDWPTNQQQAVETVCAAATNQTWVALLDQQIVGFVATTLHQASSMGEIVMLAVDPAAQQQGIGTALTQFAIEHFRNLGMRVAMVETGGDPGHEPARQTYAKQGFRLMPIARYFQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUZ2</accession>
    <name>A9AUZ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3946</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3946"/>
    <dbReference type="EnsemblBacteria" id="ABX06580">
        <property type="protein sequence ID" value="ABX06580"/>
        <property type="gene ID" value="Haur_3946"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3946"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464432_0_0_0"/>
    <dbReference type="OMA" id="PSEQMQT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3988-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="63014" checksum="60350A6DCB3AC980" modified="2008-01-15" version="1">MFPNGMILNETYEIRERIGHGGGGAVYAAYDIKLRKMVALKHLHLEGDHAIKAFGHEASLLANLEHPSLPKVYFNFNNDAGQFLVMDLIDGDDLSTMLDRQGGPLPVEQVLAWADQLLSVLTYLHTFYRQPIIHRDIKPANIKITSRGELKLLDFGLAKAEIFTNMRSAMHSVHGYTLTYAPPEQINQEGTDPRSDLYSLGATLYHLLTGRTPADGDGKTADALARTLAMAKRKPDPIIAPKNFNPSIPEHVDQAIMRSLEIDADERFASAEEFRLALAQPYAPVNNAQTKILPSTISSRAITGPPKQLTTREHSQPSPIISKPRSSYPGQPLPEAGPQAQPTPNYKRYWPLLLIVLLGGAGGGWWLNRDQQTPVVTLEQNTKTVVVAQPSQSAPTNTLMGVAGQPTITLGVATNEPTSVAVEQATATSEPAQPTTATQPTAQPAATPRPATARPATARPAATNPPVVQPTNPPAVQPTNPPAPPIDRDGDGVTDDVDGCPDVAGPNNGCPAPVEPTNPPAVADSDGDTIPDDRDACPREPGDPSRNGCPKPANTPTDRPTDRPTDRPVQPTERPTDKPTAKPPVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV20</accession>
    <name>A9AV20_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3976"/>
    <dbReference type="EnsemblBacteria" id="ABX06608">
        <property type="protein sequence ID" value="ABX06608"/>
        <property type="gene ID" value="Haur_3976"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3976"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962321_0_0_0"/>
    <dbReference type="OMA" id="VMITMYT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4018-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="59"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="32776" checksum="8CB30E1FDD160673" modified="2008-01-15" version="1">MISETQVTRDTHYVKSSKSKPISSWKVFVATTVKDLLIQFRYLPNLVGRLFELTIRIGFFYLLASITTYTVAGSVLTGRSLIVFMFGGLLLFVYSNTSFTAPMNAVSNDLHNGTLEYLYSNPSSRYAYFLGNVLSSAIVNQIVFLPLYIVLFFIAEATAFNMLMVLLVCLAVMGVLISIGIMIAMLALIWRQVGAFVQILAILFEFVSGTYFPLSAYPLPLQYVAYALPYTWGYDLIRYYSLQNKWQTILPPWIEWCILGAYAVVFMVISRILLVKAERRSKKLGLHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV23</accession>
    <name>A9AV23_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS204/IS1001/IS1096/IS1165 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3979"/>
    <dbReference type="EnsemblBacteria" id="ABX06611">
        <property type="protein sequence ID" value="ABX06611"/>
        <property type="gene ID" value="Haur_3979"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3979"/>
    <dbReference type="eggNOG" id="COG3464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2843869_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4021-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="65" mass="7009" checksum="47A6CD1A20E22D97" modified="2008-01-15" version="1">MDAWLADTEASVIGFASGLRTDYAAVANALTQPYGNSPIEAHIHRLKLINGRANFDLLGKRVLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT5</accession>
    <name>A9AVT5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4053"/>
    <dbReference type="EnsemblBacteria" id="ABX06685">
        <property type="protein sequence ID" value="ABX06685"/>
        <property type="gene ID" value="Haur_4053"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4053"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_1_2_0"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4096-MON"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="17418" checksum="4BE2D9204A8002DA" modified="2008-01-15" version="1">MTIVYLAIGSNQGDRLANLQAGLAALAPAVQLTNYSSVYETAAAYVEDQPPFLNAVVAGTTELAPHALLALLKQIEHDCGRRPGLRYGPRPLDLDILLYGELELQTNDLIIPHLRMFERDFVLRPLAEIAPNQVNAEQLAQATQGSVLAVVYSAKQLQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU9</accession>
    <name>A9AVU9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ordered locus">Haur_4067</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4067"/>
    <dbReference type="EnsemblBacteria" id="ABX06699">
        <property type="protein sequence ID" value="ABX06699"/>
        <property type="gene ID" value="Haur_4067"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4067"/>
    <dbReference type="eggNOG" id="COG0636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148047_5_0_0"/>
    <dbReference type="OMA" id="NIATVGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4110-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="PTHR10031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="9"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX06699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="7574" checksum="43CF2BC2386694C4" modified="2008-01-15" version="1">MTDTGARLLAAALAIGLAAIGPGIGVGLLVAGALQAIARNPETEGSIRTNMFVGIALTEGLAIFGLVISLLIGFGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA4</accession>
    <name>A9AWA4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2114"/>
    <dbReference type="EnsemblBacteria" id="ABX04754">
        <property type="protein sequence ID" value="ABX04754"/>
        <property type="gene ID" value="Haur_2114"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2114"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="WAMAVAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2142-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="550"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="630"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="872" mass="96662" checksum="56A2666BBE15D6C6" modified="2008-01-15" version="1">MTQIAVNSPAAFGKQLRLLRRRARLTQAELGIAVGYSDAQICRLETGRRPPDLTTLIALFLPALDIEAQSHEAQQLLELAASAREELIAEPSQNNHGALNQALPTLASHLPSPTSYFLGRGAEQQRILQWLNNPTIRLISIVGLAGIGKTQLGLQCLHQFASQSEQQCVFVDLVTANDPESMVQAINKALEISESPDEHPLSLAISQLEQQPSCLLLDNCEQIQDASRVISLLLSEVPTLKLIITSQVALRLSAEHVLQLTPLAVPNLLALPPLAELAQIEAMALLLARLQVHNPKLELTAKNALALAALCVRVDGVPLALELVAASGRLFDPEALLSELASHFLSMRRRGRDLPSRHYSVTTALTWSYQQLDSASQRLFERLSVFVSGWTVEAALAVCGPEYQRHELIEQLNVLLDHSLIQQQTNDDSTRMSMLTMVRTFAQEQANKHAEHDLLKSRMLDYLIELAQQAEQPLRSGNNQAMWIQRLEAEHDNIRAGLNWAWQHNAHQRGIQLVGYVWRFWYMRGYLREGRRWFENLLISHEPTADVDFARALDGVGILAWRQSDYQQAEQWYQQALAIYQTTQHTAGQAQVLGHLGLVAMDTGAYAQAAAYYEQSLPLYQAVEDQSGVVATLHNLGNLYCQQSENQRASQLYQECLQIYQEMGDQSGVALIALGLGVIARDEQRLDAAQASFEQSLSLARELGDDWNEATALINLGNIAIDTSQPKLGLEHYQTAKQIFERLGDQQSLCLIENRISNAHWLLGDYAQAQAGYRQCLMLAHAIGFDGGIIEGLEGLAHCLSQTLPTTAAQLMAYAAQMRSTKGYPIIPADEAGYNQIGQEIQAHLSTTAWQQAYQQGQQLSLQRAVSLALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH5</accession>
    <name>A9AWH5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="15">ATP-PFK</shortName>
            <shortName evidence="15">Phosphofructokinase</shortName>
            <ecNumber evidence="15">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pfkA</name>
        <name evidence="17" type="ordered locus">Haur_4102</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 15">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="15"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4102"/>
    <dbReference type="EnsemblBacteria" id="ABX06734">
        <property type="protein sequence ID" value="ABX06734"/>
        <property type="gene ID" value="Haur_4102"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4102"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_0_1_0"/>
    <dbReference type="OMA" id="KFAVICV"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00339">
        <property type="entry name" value="Phosphofructokinase_I_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012828">
        <property type="entry name" value="PFKA_ATP_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02482">
        <property type="entry name" value="PFKA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="16">
        <location>
            <begin position="3"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator; shared with dimeric partner" evidence="15">
        <location>
            <begin position="21"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="186"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="260"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ABX06734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="35401" checksum="0BAE4A26217F175E" modified="2008-01-15" version="1">MHRIAVLTSGGDSPGMNPAIRAVTRTALHAGCEVFGVYRGYAGLIQNDMRRLEYKDVGGIIQRGGTMLLTARSPEFMTPAGREKAMENLRWHGIEGLVVIGGDGSLRGAAALTAEHGLPTICLPGTIDNDMYGTDMSIGADTALNTVLEAIDKIKDTASSHQRAFIIETMGRHSGYLALMGGLAGGAEAILIPEIPDTTIEDVVEVIKRSFRKGKTNCVIVAAEGAHLNAQTIQDQINQIDAEESGFSFSFRTRATILGHIQRGGSPSAFDRTLATRLGSGAVEFLLSGKNGGLVGMQSRKLTVTPYDEVLANPKVLDAKLYELSKILDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWM1</accession>
    <name>A9AWM1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4148"/>
    <dbReference type="EnsemblBacteria" id="ABX06780">
        <property type="protein sequence ID" value="ABX06780"/>
        <property type="gene ID" value="Haur_4148"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4148"/>
    <dbReference type="eggNOG" id="COG3393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064724_1_0_0"/>
    <dbReference type="OMA" id="INFVYTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4194-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="136"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="31233" checksum="2800FDDAAB4BEA21" modified="2008-01-15" version="1">MRVEQYFSVDPFIHEHREFLLQHEAENNLPLGLSMRIQNGWLPANPPFFAAIRDEQGVVGVAVMTAPNALTISALRDASLADQATQALANYLVSQNIAPNGVFSAPATTTAFCMAWQAKTGRRPLLSMHERVYTLTEVIPPTPVAGSLKQATNADIEWLTEWLAAFHAEAVPNEPAWDSRAVAERQIATASAWYWEVDGKPVSSLASSRPTVNGICIGAVSTPRQFRGNGYASNAVAALSQQLLDQGFRFCMLFTDLSNPTSNKIYQAVGFRPVCDVDQYRFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWM7</accession>
    <name>A9AWM7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein/LacI transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4154"/>
    <dbReference type="EnsemblBacteria" id="ABX06786">
        <property type="protein sequence ID" value="ABX06786"/>
        <property type="gene ID" value="Haur_4154"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4154"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_2_0"/>
    <dbReference type="OMA" id="ACEEMAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4200-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735048" evidence="1">
        <location>
            <begin position="24"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="53"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="35958" checksum="508E49A2256FA157" modified="2008-01-15" version="1">MSQHALIKRLLILVTLLSLVACGSSQTNQTVTADKPTKTYADLVIGYSQIGAESRWRTANTLSIQESAQDLGVDLRFADAQQEQINQINAIRSFITQKVDLIGVSPIVADGWDEVFAEAKAAGIPIIVVDRTANVPDELITAFIGSDFVLEGERACEEMAQLLNQKGTIIELEGTVGSAPARDRKTGFHNCLKKYPEMQVLVSKSGDFTRAQGKTVLQGLIKQYGTDFDAIYAHNDDMALGAIELLKELGIKPGVEVKIVSIDAVEDAFKAMIAGDLNVTVECNPLLGPQFFETALKIVNGEPFERWVKSNEGIFRQATAAQDLPKRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU8</accession>
    <name>A9AWU8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase with FHA domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0701"/>
    <dbReference type="EnsemblBacteria" id="ABX03349">
        <property type="protein sequence ID" value="ABX03349"/>
        <property type="gene ID" value="Haur_0701"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0701"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_544885_0_0_0"/>
    <dbReference type="OMA" id="EQYGKGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-713-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="417"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="500" mass="55199" checksum="DA213B3933E100AF" modified="2008-01-15" version="1">MFADLLPDGTILQGQHDQYRILGIIGRGGMGAVYRGERLSDGSTWAIKEMRPPIEAAPEEIAENRKLFDQEAQLLQTLDHPNLPKVVDSFEQAGRPTLVMEFVQGKTLEDKQREMNAPFFQRDVLNWGVQIARVLNYLHSQNPPIIFRDMKPPNVMLTPEGIIKLIDFGVARTYKTNKSKDTVAMGSAGYAPPEQYGKGQTDARADIYALGATLLHMLTNLPPVPLQTPKDGSLIKHNQSVTPEMEQVIIRSMAMDREKRFQTMASFEQALLAVDRGVIVPDKRDDPTMMSMPAPVLNNPNPNPNPAPAWGNPNPNPNPAPAWGNPNPAPAWGNNPPNYQQPVPQPAPPSWAPPVQTPAWSPPPQANGPICDQCGRMNKPNARFCAGCGAAIKRAVPKLVITSPRAVWELALTHFPCRIGRRDPAQNHHPEIDLAEHDRGVASRRHAVIEQQGDHHLLIDLGSINGTSINGVPMTAYQPHHLRPGDRIRIGDVEMVFSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV2</accession>
    <name>A9AWV2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0705"/>
    <dbReference type="EnsemblBacteria" id="ABX03353">
        <property type="protein sequence ID" value="ABX03353"/>
        <property type="gene ID" value="Haur_0705"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0705"/>
    <dbReference type="eggNOG" id="COG2947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041799_2_1_0"/>
    <dbReference type="OMA" id="LWDGIRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-717-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14773" checksum="FA1D7F114743A1CA" modified="2008-01-15" version="1">MAFWLLKTEPNEFSWEDLLRDGSTVWNGVTNAQALINLRAMQLDDQCLIYHSGDVRAAVGIARVSRTAYPDPNSENPKHVVVEIEPVGPLAQPVSLAQIKAEPSLADWALVRQSRLSVVPCNPEQWAWIIAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW0</accession>
    <name>A9AWW0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0713</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03361">
        <property type="protein sequence ID" value="ABX03361"/>
        <property type="gene ID" value="Haur_0713"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0713"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_1_1_0"/>
    <dbReference type="OMA" id="PDVLMTL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-725-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="319" mass="36147" checksum="8EE70025DF61BF77" modified="2008-01-15" version="1">MYSPTTRLLTILELLQSHQRMRGAELASRLEISQRTVRRYVVMLQDMGIPVEAERGPDGAYYLGRGYTIPPLMINPTEALALVLGLRMIHALQFPVDATAIEGAIAKLERVMPTILLDQVRAFQEAITFHVAPPPALLQPSIVASLSVAVHTRQQVWLSYQTYNGDASVRVFDPYGIVYYQGYWYSVGYCHQRNDLRTFRIDRIQELKLLNQSFERPQDFDALHHMHTTLATMAGPYAVEIVFAATMEQVRHVLPPAAGTFEQSEVGIIWRRETYELTSIAHRLLQIDLPATIRQPSELKAMMHQLAAKALGMTLNQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX02</accession>
    <name>A9AX02_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2170"/>
    <dbReference type="EnsemblBacteria" id="ABX04810">
        <property type="protein sequence ID" value="ABX04810"/>
        <property type="gene ID" value="Haur_2170"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2170"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_625256_0_0_0"/>
    <dbReference type="OMA" id="HANANRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2198-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="344"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="438" mass="48317" checksum="0E01EC6D9AC14301" modified="2008-01-15" version="1">MLFQDSAKLRQSAETQAIPIPNHTHEAEQFSGGLSIKRILQIVALLWISYFLILTGLDWVSLMSRPDTSPLPWFYYAIHITLAGVVFGLATWDAAQQRLGRVFMPLIIGLISVVPILLTPLITSGPGPITTEPGLVVMRLCPMLCVAVVIVAWQYTWRQVVWFCLVTGALILLPILLRAPRFSSAVAITIVQTSTFLVFGYALSALVQRLRLQNAALIQAHEQLRDYAGTQERLAISRERNRVARELHDTLAHALSGLIVQLEAAKLYREIEPTTSHKLQDSALDAARHGLQETRLALKALRARPLDDLGLALALRQLAEQLASTAQLTLDLSISPKLPPLALEVETCVYRVAQEALRNAIRHANANRLDVSLTCIDTELCLVVRDDGCGFEFQSFSTADHFGLAGMHERAAELGGQLSINSQLGLGTWVELRFTTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX34</accession>
    <name>A9AX34_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2202"/>
    <dbReference type="EnsemblBacteria" id="ABX04842">
        <property type="protein sequence ID" value="ABX04842"/>
        <property type="gene ID" value="Haur_2202"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2202"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_5_0"/>
    <dbReference type="OMA" id="MMEIENI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2230-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31660" checksum="A6A073147297450A" modified="2008-01-15" version="1">MRIFLTGASGFIGRHVAEELHQAGHQLTCLVRQKPTTPINSATQYVAAEWLKPTTWLDQLAEHDMVINCVGMLRESRQASFQAVHTSVPIALFKAAAQYGLQKIIQISALGADVAAPQAFVRSKALADQALSQQSVPWVVLRPSFVYGAGCYSMELFRRLARLPITPILGDGSYQVQPIQIGDLVRAIRQAVEDPTITNCLIEAGGSEQLSFRQLLERLAASQNRQLRPWFVPNWLTQIIAQIGTTTGLGPINRAELSLLLQGNTCDLSDFRQHFGFEPRRFEPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX36</accession>
    <name>A9AX36_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="2">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.17" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2204"/>
    <dbReference type="EnsemblBacteria" id="ABX04844">
        <property type="protein sequence ID" value="ABX04844"/>
        <property type="gene ID" value="Haur_2204"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2204"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_2_0"/>
    <dbReference type="OMA" id="SVDGGCT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2232-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="55"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="35720" checksum="A0D69A05876BBE0F" modified="2008-01-15" version="1">MEKPTNKPQVLVNSVGYSRRDFLRFGAFTTVGLLAGCGTTSATPVSTATPTKPKIGLVMKSLSNEFFQQMQAGAEEYARQNATRFDFTATGINDERDFATQIASFERLVNEQYDVIVLAPADSIALVAPVAKAVKAGIVVINIDVALDEATKKAAGIDLAFFGPDNRAGAKMSGEVLAKALGAGGKVAVLEGNPEADNAVQRRLGFDDAIADGSLNLVVAESGHWETSEGQSITAAWLKKYPDLQGIMCANDSMAFGAVQALEAANLLDKIKVVGFDNIPAVQPLIKDGKMLATVEQYGAQMAAIGMDYGYRTLKGEKFSGWIRTELKLITKDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX39</accession>
    <name>A9AX39_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2207"/>
    <dbReference type="EnsemblBacteria" id="ABX04847">
        <property type="protein sequence ID" value="ABX04847"/>
        <property type="gene ID" value="Haur_2207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2207"/>
    <dbReference type="eggNOG" id="COG1813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="VGDRWGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2235-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="901" mass="102127" checksum="9CBFBCACE1182D80" modified="2008-01-15" version="1">MDDRPIFPEWIKQARKQLGLGRAELAHQVGCSLAMLRQLEYGTRRPSRQLAERLASFLQIPAEQQSLFVQTARVHQPPSPINPVPLVKRLPEPTQPLIGREELLAHASQLLLQSSTRLLSIVGPGGVGKTHFASQLAQQIQAHFSDGSFFIGLASLHDAEQLPTLIAQTLEIPQPTHQSTLEQLIGAIDQRSILLMLDNLEHVMMVVPIISQLITQCNKLKMLITSRFALKLHDEHLIDLPPLDVPQHPPEHQASAETNYSAVELFELRAKMVQPQFSLTAQNRAIVGEICRRLDGLPLAIELAAARIRGLPPQAMLARLDRRLELFDQGNSDLPERHQTLRNLIAWSYTLLTPNEQTIFRTLSLFANHWTLGAAEYLCQAQIAKPQVLTILLNLLDKSLVREESSNDGIATFAMLEIIREYGLEQLEQTSEAHALRWRHAHYYIQLAQHAEQQLGQQEALWLERLTWERSNLWDALNWLVAQQAAEALLQLIGSLWKFWQIRHLWREGLHWIELALALPLVNSEAYQQARAKVLWGAGWLAVDLHQHDLAQAMFEQSLHLATSLDDQQGIARALHGVGLLAEWAGQRDFAMRAYQESLSLFRQLDDQEEIAWSLFHLGAALQSQGQAKQARHFLEAALATSRRLAHSWSIVHQTKALGQMAIDQGRYADAELLLNEGLKLAQNHQYQQIYLEILRHLGRSALEQGHYQQARERFQASLEQAQLLKEPSAIRWASIHLNWLGILEGDLTQAYAFEQQLAIFERDEPAWAIAWLKARLGTIALLKCQPEVAQSWFLASIQMYQANDLPWGLVECLEGLAHSLWLSKQAHQAAACLQLLSAAEQQRQSLPRLRSVPEQAAWQTSLAWCQQQLSPEQFAHIWQTGATQTLEQLLKPFNHETQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC5</accession>
    <name>A9AXC5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4213"/>
    <dbReference type="EnsemblBacteria" id="ABX06845">
        <property type="protein sequence ID" value="ABX06845"/>
        <property type="gene ID" value="Haur_4213"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4213"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031866_2_0_0"/>
    <dbReference type="OMA" id="SMRIPIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4260-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="43"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="455" mass="50002" checksum="A5B7460812C607BE" modified="2008-01-15" version="1">MTSLDLRLTLSRSSVPANTGEQVLYVLAEVVGQGKTNQRAPVHCVLLVDCSPSMRVPIADAALFRELMRRGAAHEVMLDGVPVWKIRDDLMDEVRRRAQSPSRWLGQAVRGAAERLNADDQLSIIGFAEKAHAVLKAKSPTDVVRLEGSVAILERGDLGRSTRLAPGLRSTIDLLDSMPSTGFSQRIVVLTDGFVEDEQQAFAYARHLAARSIPVSTIGLGVEFQEQLLMSFADQSGGQSSFITDPSDLPNLLDVEFGKAHAIIAQKARLDLRLAHDVHIKRILRIRPALGEVPIPEFEAGSGSLSLGSIEQRAKAAWLLELRIPDHVPNIYRLLRLSLQADDPQGQSLEPINRDVVVEYHPNADQALNPELVAILERVTAWRLQNKALEQAAQGDQAGATRQLQAAVTRLVDLGEHELAKQTAAASQTLQETGQINPEQTKTLRYATRRLTEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXE8</accession>
    <name>A9AXE8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4236"/>
    <dbReference type="EnsemblBacteria" id="ABX06868">
        <property type="protein sequence ID" value="ABX06868"/>
        <property type="gene ID" value="Haur_4236"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4236"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4283-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="14168" checksum="E10CCB831C7EA0DA" modified="2008-01-15" version="1">MFKSTPQSAQIVIIEDSATVRDMLAHIIRDDGYQVATYTTAVDGLKYLQSSQPPRLILLDRVLPYMSSEEFLEALQAEPRLSAIPVVIISTYLYDEPAPLPYTVGYLEKPIAIDDLMRVVRRYCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI3</accession>
    <name>A9AXI3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Biotin carboxylase</fullName>
            <ecNumber evidence="3 9">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_0749</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="3 9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0749"/>
    <dbReference type="EnsemblBacteria" id="ABX03397">
        <property type="protein sequence ID" value="ABX03397"/>
        <property type="gene ID" value="Haur_0749"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0749"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_2_0"/>
    <dbReference type="OMA" id="ITHFHTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-761-MON"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="455" mass="49741" checksum="6ABDE781BBB6E68B" modified="2008-01-15" version="1">MLRKILIANRGEIAVRIIRACHELGIKAVAAYSEADRDSLAVRMADEAICIGPPPPAKSYLNAPALISAALISDCDGIHPGYGFLSENPYFAESCRECGLTFIGPSADSIQRMGDKALAKQAMKLAGLPLVPGTENPLTSVEEAQSLADGIGYPVLLKAVAGGGGRGMRVVNQPDELARAFNTARAEAEAAFGRGDLYMEKYLPVVRHVEIQILADQHGHAIHLGERDCSLQRRHQKVVEEGPSPALTPELRQKMGEAALHGVREIGYYNAGTMEFLLDHQGNFYFMEMNTRLQVEHPVTEWLTGLDLVKWQIRIASGERLTLTQDDIKIRGHAIECRINAEDADRDFMPAGGTVDLYLPPGGPGVRVDSHLYSGYRTPTNYDSMLAKVIVWGETRLEAIERMRRALSECVINGITTTLPFQLRMMNEPAFVSGDVATHTLADILNQQAAKEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ5</accession>
    <name>A9AXQ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0821"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03469">
        <property type="protein sequence ID" value="ABX03469"/>
        <property type="gene ID" value="Haur_0821"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0821"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_6_0_0"/>
    <dbReference type="OMA" id="IPHGHYR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-835-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="351" mass="39121" checksum="151603A7E4C5DA9C" modified="2008-01-15" version="1">MSITIYPIPRLLATNPYLDLLYAPFAAWPDVQIARQPFAQTLRHGLLHGGQRVLHWHFFDELTQQPNQAATALRSISFIALLRLLALREAKLVWTAHNLEPHELRYPQWAQRCYQAMAQAAGQIIVHSQPAAQLLDQRYQVATKTQVIAHGSYIGVYGEAWEQAAARKHLQLTPEGFVALNLGTLRPYKGVELLLEAWSAELGRLLIVGAAKDQRYAEQLQQQATNPSITLRPQFIADSLLPAWFAAADVVVLPYRKTLTSGMLLAALSYAAPVVAPDLPPVRELIRDGENGFLFEVNNAASLRAALQRAAAHPDRQALRQNALQTVQALDWGQIANQTAAVYRRLFEKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY57</accession>
    <name>A9AY57_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06939">
        <property type="protein sequence ID" value="ABX06939"/>
        <property type="gene ID" value="Haur_4307"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4307"/>
    <dbReference type="HOGENOM" id="CLU_2493648_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4359-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="86" mass="10422" checksum="8EBCA1CC4E8DEF0A" modified="2008-01-15" version="1">MDFEKHYIGELIDEISKNDNIKIKINNKDILRIFRNSIMHFHTTIRNKGVNVEEFIYDKNDFIIFTENVNILMCEIRRVKTYILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY69</accession>
    <name>A9AY69_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol-phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4319"/>
    <dbReference type="EnsemblBacteria" id="ABX06951">
        <property type="protein sequence ID" value="ABX06951"/>
        <property type="gene ID" value="Haur_4319"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4319"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_4_0_0"/>
    <dbReference type="OMA" id="WRTRAYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4371-MON"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="28038" checksum="74DCC3888C411E6D" modified="2008-01-15" version="1">MPSLRELLDVATEAAYLGGRRTLAYFGADVQVETKGDATPVTRADREAETIIRDYIGRYFPSHTIIGEEHGEQKGDADYRWIIDPIDGTKTFIHGVPFYGVLIGLEIKGEASVGAVYLPAFDEMLAAANGLGCSWNGRPAQVSKVDNLADATLLTTSVTSAMKRSNAYETLVSKTKLQRTWGDCYGYVLVATGRAEIMLDPAMNPWDCAPMLPILREAGGHFTTWAGEATIWGADGMATNAALHQEVLAILATEQRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYC8</accession>
    <name>A9AYC8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0862"/>
    <dbReference type="EnsemblBacteria" id="ABX03510">
        <property type="protein sequence ID" value="ABX03510"/>
        <property type="gene ID" value="Haur_0862"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0862"/>
    <dbReference type="HOGENOM" id="CLU_1439271_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-876-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="21727" checksum="D9096CAE15D02833" modified="2008-01-15" version="1">MYLAPAADTPSTLSWWQRFILGWYLPASFALIWLSGPLWRGKKSTNEWLYAVSNRQISISGRYDLLHQLFFAGLFIYLGYLLLHRPQKHALLFSLTVASLIGGYLAHKALIGSPLRVGMIIWELDFDELGAYNVRFGYVLASSVVSCSVVAFQSYLYPALASNWLNVTLTWFRVLITLIAFYSIYAGSYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF1</accession>
    <name>A9AYF1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0885"/>
    <dbReference type="EnsemblBacteria" id="ABX03533">
        <property type="protein sequence ID" value="ABX03533"/>
        <property type="gene ID" value="Haur_0885"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0885"/>
    <dbReference type="eggNOG" id="COG1482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020529_0_1_0"/>
    <dbReference type="OMA" id="DTFFINT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-899-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014628">
        <property type="entry name" value="Man6P_isomerase_Firm_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036894">
        <property type="entry name" value="PMI_Firm_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="35862" checksum="A23272BDCCAC90B4" modified="2008-01-15" version="1">MSVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQSLAQVTSQFGAALVGTTTSERYGNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHGKTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPELLRQVAVQAGDLVFVPAKTIHAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPTKLNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGMSVIVPAQLGQYQLYPEPSAELLRAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI5</accession>
    <name>A9AYI5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0919"/>
    <dbReference type="EnsemblBacteria" id="ABX03567">
        <property type="protein sequence ID" value="ABX03567"/>
        <property type="gene ID" value="Haur_0919"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0919"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_447440_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-933-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="456"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="610" mass="66930" checksum="499426E07C8E6BE6" modified="2008-01-15" version="1">MTQAIDLHSQLQSDPQVQLPTRPRISDEIARVWHNEQLLLLLGGPQDVVLRGKAVRNLLPQLLPLLNGLNTRETIGERLAQFKPTTIDDSLQLLHVQGVLEEGPLPSNTLDPQVARAFSQQLAFYSRFVDQTRVCRNRYEVLQRLQTTPLLLIGGERLVAPLLHQLAQAGLGRATWLANSAPTTTYALPHLALDLQVPQADQLPAAVDHWLAEHHDGLICLLTSTAQAELTQALNQRAIQAQTRFTRLWLHPQHIELGPTTFAGEAGCYACAEQVDSHEPQLSEPTAPLSLNEQLALSQASLVVGNLISGLSPVITGGVRYVLDPTTLEFVAQSVHRLVLCPVCGQPNLDAPRDLLVGAGHFENLPLWYHANTDERSYAIFPKAHQQHYAPKNAIAIVSGAKGYTNSQRYALGELQGQWQPDSTVDLSVQLPVQTSIAPLAWLFEQAFVRKPATQVIAAGQRFVPSGGNLASQTVYLLNHKLSNLAAGIYHLNQHDASLEAMRPQFSWDDVAKAFPSDPLNQQTLGLIVLTAAIGRVEGKYGAKSYRIALYDCGVAAQAIEFLAAAAGWQIEQISAFYDQELRDLLQVYSPSETPLLVLRLVAPNPEVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR1</accession>
    <name>A9AYR1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2399"/>
    <dbReference type="EnsemblBacteria" id="ABX05039">
        <property type="protein sequence ID" value="ABX05039"/>
        <property type="gene ID" value="Haur_2399"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2399"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_0"/>
    <dbReference type="OMA" id="CVATTHW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2427-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="220"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="36256" checksum="6C469E3AC42BAC03" modified="2008-01-15" version="1">MQESIRPIYVLLLPHVQLLDCAGPSQVFFEAMLQGANYQLIFCGIDSVVTSAQGLVLQTQSGLPEIQPEATILIPGVQLDYYADLSTPIDPKITHWLQASAAAGCRIAAICSGAFVLGEAGLLDNRPCTTHWSALELLQQRYPKAQVRQNVLYIQADRIITSAGISTGIDLALALVEQDYDALLVAKIARQLVLYLRRSGQQTQHSVYLQYRNHLHIGVHRVQDYLAEHLAETISLEQLAAIAKLSVRSLNRAFRTTLGLTPISYQQQLRLELAANLLHNPAWSIEHIAQQVGFSDTRHFRRLWQRYFGTNPTQSRHTQEPNQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT2</accession>
    <name>A9AYT2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05060">
        <property type="protein sequence ID" value="ABX05060"/>
        <property type="gene ID" value="Haur_2420"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2420"/>
    <dbReference type="HOGENOM" id="CLU_2409252_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2448-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10045" checksum="E4CDF0DB1D53D9C8" modified="2008-01-15" version="1">MNTRFLGIPSVVWSMLALVIAAIFVYVWPSDKVPGDTTSIRYLILRWGHTLVWVLIAGFIFLRSVGATSLASLLGGLAGITYLAFIATLVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU9</accession>
    <name>A9AYU9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver and ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4357"/>
    <dbReference type="EnsemblBacteria" id="ABX06989">
        <property type="protein sequence ID" value="ABX06989"/>
        <property type="gene ID" value="Haur_4357"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4357"/>
    <dbReference type="eggNOG" id="COG3707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_65_0_0"/>
    <dbReference type="OMA" id="ICPVVIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4410-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008327">
        <property type="entry name" value="Sig_transdc_resp-reg_antiterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036382">
        <property type="entry name" value="RR_antiterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="22301" checksum="2A9A67405838242D" modified="2008-01-15" version="1">MSDEQRATIRILLAEDNELVALTMEEYLTDLGFQVVGVARTGTQALELARQLEPDMAILDVKLPELEGTEVAARLYAERPMPIVMVTAFTDRDTIRKAERAGALGYLVKPVTMEALTPAIDIALARFAEIRALRQEVDALHESLEARKLIERAKGILMQRLNISEHDAYERLRHRAREKRVKLKDIAQTIIDAEALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX4</accession>
    <name>A9AYX4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4382"/>
    <dbReference type="EnsemblBacteria" id="ABX07014">
        <property type="protein sequence ID" value="ABX07014"/>
        <property type="gene ID" value="Haur_4382"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4382"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037945_1_0_0"/>
    <dbReference type="OMA" id="NNDHYWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4436-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="28674" checksum="0B419E455909658C" modified="2008-01-15" version="1">MDWNLWSEQAQDFAIRVLPRILAAIVVLLTLRYGIRLANGATNRVLKRVELPSEAENLILRLVRILVIVAGLVIVLLVMGWGQLALSFVAGLGVSGLIIGFALQDITKNLAAGILLLFQRPFRVGDRILVGNDEGTVTDIAVRATTMRTADGREVMVPNATIYTGTITNLTRYVQRRHSVELTLKRDVDSAPVVQGLAEIARTTEHVLEKPAAEVLITAVKADGLIVETRFWLPSKGIDSNVVRSNLAGRLRAKALAEDWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ02</accession>
    <name>A9AZ02_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4410"/>
    <dbReference type="EnsemblBacteria" id="ABX07042">
        <property type="protein sequence ID" value="ABX07042"/>
        <property type="gene ID" value="Haur_4410"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4410"/>
    <dbReference type="HOGENOM" id="CLU_422606_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4465-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735116" evidence="1">
        <location>
            <begin position="18"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="648" mass="73241" checksum="5E5B57BEBE2441C6" modified="2008-01-15" version="1">MQRRSNYWFLLISFVLAACGQPDSLLSTSPTVTMADQANPTSTPINGGQSSDLAIIEQLQRPAQSQPYEFAPNPMSANINDWLRILMPKVMLDQLMTLDLDSNSNPNDLPIKAIDDYFTDTPIDKLIEHYRTSLAATNWIAQPIQHINPQDTTLIFEHEQTQLYIFIFTPMNTDQLFVSIKLLQTNHSRPNLELPLVNTSDIFTTHDVRFPSDTTINNELLNDPARGELLKRDLLMPIRQLQSFWPGEITLEASLVAETFGSQQITYDLAKAISELGGWQASNTLLGSDSYIGPPLLRFVDNTIQVLLMNQLSEHEYLAQSSPNDWLLGMHLLTLRSSEQPNFTLDPSFFSPIEALEIPTQPDQQDYQLGTDRLVDSLLYGWQHNQITKTKLQAYINTNYPPESACSPSTTNPNSNIRYSVFSSDSNPSQISATYKQTLTEPNNWNNLEDDTTFAFYGVRTEQGYHGGTLSLIERSRYNLQLSGSIGIISESTPNSVPQISFRGQEYPSYIGVAWLVEPITHSLPLLPDAMVFNSVSHERFNGYAYGWLRSLNYQRSSNDCKEITYIDGVQALVIDSSDLTLAPNFYDPILLGQGWQKIVMSDQHHRYIKTEQDGKVINTINIRWQLGSRITGDIIQVVMIDSSITYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ86</accession>
    <name>A9AZ86_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0984</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0984"/>
    <dbReference type="EnsemblBacteria" id="ABX03632">
        <property type="protein sequence ID" value="ABX03632"/>
        <property type="gene ID" value="Haur_0984"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0984"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_39_2_0"/>
    <dbReference type="OMA" id="FLVEMFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1000-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="481" mass="51616" checksum="0AEFD6C9DCB8E158" modified="2008-01-15" version="1">MSNTPMPSQHSTVVSQSTIWKVIIASALGTMIEWYDFYIFGSLAAVIATNFYQSGNETAALLETFATFGAGFAARPFGALVFGRIGDIVGRKYAFLVTLLIMGGATTVIGILPTYASIGILAPIILVIIRIIQGLALGGEYGGAAVYVAEHVPDHKRGFYTSFIQITATLGLFISLLVILIVRTSMSKAAFDSWGWRIPFLLSIVLVGVSVYIRSKMSESPLFTKLKHAGKTSKAPLKDSFGNRRNWKVILTVLFGAAAGQAVIWYTAQFYVNSWLKTQAKVPANTVDTIVAIALFLGMPFFVVMGALSDKWGRKTVMMAGNLIGAIAIYPAFMALKAAAGPITPAVLDEAGKVITPAVANNPNTVLLTLIIFGLVLCVCMVYGPIAAFLVESFPAKIRYTSVSLPYHVGNGYFGGWLPFIATAVVSSTGNIYAGLWFPIAIALLTFVVGMVLLKETKDNSLHEEASDNPMATEMDLIAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD0</accession>
    <name>A9AZD0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2434"/>
    <dbReference type="EnsemblBacteria" id="ABX05074">
        <property type="protein sequence ID" value="ABX05074"/>
        <property type="gene ID" value="Haur_2434"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2434"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_0"/>
    <dbReference type="OMA" id="FMHGIYS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2462-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20960" checksum="B701DD08A0E4B86C" modified="2008-01-15" version="1">MDNRATLLEQALQLFAQRGYDAIGVQEIVEHAGVTKPTLYHYFGSKRGVLEALINERLQPLIDQLANATTHANDVPASLAAIFQLYFDFAQAEPLLYRMQLAMWFSLPDNEAFQIVAVAAAQQQALLESFFVRASSFHGNIRGRQRVYAATLLGTINTYIGLWLSGAIQATPHIIHQAVQQFSYGIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI5</accession>
    <name>A9AZI5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2491"/>
    <dbReference type="EnsemblBacteria" id="ABX05129">
        <property type="protein sequence ID" value="ABX05129"/>
        <property type="gene ID" value="Haur_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2491"/>
    <dbReference type="eggNOG" id="COG1479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011736_2_0_0"/>
    <dbReference type="OMA" id="YVFRRAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2519-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="12"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="396"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="656" mass="76798" checksum="93893FD996F25AC8" modified="2008-01-15" version="1">MKASETKFQPIIEGTKQYVVPLFQRAYSWDRREWDILWEDITDLCENEEPKSHFIGSIVTMPTPSVPEGVGKYLLIDGQQRLTTIFILLCLLRDKAIDIGNEELGNEIQQTMLVNPFKKGNDYFKLLPTQVDRLAFQSLITKQSFSGDSQIGKCYKFFERKIDSSNILEVNKVLTSRFSVVSILLDYDDNPHLVFESLNAKGRQLTQSDLIRNYFFMRIHINDQEDIYNRFWNPMQSNLKDNLTECIRHYMMRNGVIVKQGDVYFTLKERVEKGDALKSLEQIAVFADYYQKLINPSIEPNITVRNALFRINRLEITTSYPFLLSCYHDYANKDLSPNDFTEVLHIIENYILRRFICNYSTNQYNKLFPFLYDWAKSNNPSNFIQGLREVLQERGYPNDALFKSHLIESKLYGKGERLVKTKLILETLESHFHHKEQTSFETLSIEHILPQTLTEWWKQHLGEDWQADYELAVHTLGNLTLTAYNSELSNDTFPKKQMYFQQSHIELNKYFQNIEFWNRDAIETRASILADIALLCWPYFGSNKPVTFATSANDVTGKTPQTLIFLGSRIPVDSWRQVMLKTLNTIADIEPDMFEVITREYSRFISSDSTRFKRKSELDNGLFVDVNLRSRDIYRLCQQIIITIGLSHENWGVETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZM1</accession>
    <name>A9AZM1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2527"/>
    <dbReference type="EnsemblBacteria" id="ABX05165">
        <property type="protein sequence ID" value="ABX05165"/>
        <property type="gene ID" value="Haur_2527"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2527"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_3_2_0"/>
    <dbReference type="OMA" id="VSESTMY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2555-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="117" mass="13433" checksum="B0EEB3D805192774" modified="2008-01-15" version="1">MIVQATEQEGYEKLSQELRRGVVILAALSQLQTPQYGYSLIDRLTERGFSIDQGTLYPLLRRLESQGFLDSMWNVEGSRPRRYYVINQAGRTLLAQLSHDWQSLAEVMQRLLTNEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV1</accession>
    <name>A9AZV1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4524"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07155">
        <property type="protein sequence ID" value="ABX07155"/>
        <property type="gene ID" value="Haur_4524"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4524"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_8_0_0"/>
    <dbReference type="OMA" id="LHHFPMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4579-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="3"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="421" mass="46398" checksum="2B46D60C2C4CA7FD" modified="2008-01-15" version="1">MRILIIAFGTRGDVQPMVALGLALQERGHSITLLVSSNFKSWVEEFGLQVATARVDIQQMMLSDHGNDWVKHGANPIKQRNAMRRLLKQHALTMVEDAWQVAQNCDVLISSFTSDVFAVTLAEVLNVVHISTPLQPAMLATRCGPASAAAILPNHESIINYWFGRWVLEPFMWQVGGDFINQFRQQQLKLPAQSVREYAQRLRQTTIIQGYSPAIIPHPSDWPANIQTVGYWMLPPDEAWQMPPELEQFLADGPTPIYIGFGSMTGANPDAFTELLLKAVAHSGQRAIIQTGWAGLGQIELPKTVFRIGSAPHERLFRHVKAAVHHGGAGTTAASLAAGLPTVIVPHLGDQLRWGQRVFDLGLGPKAIPRNKLTVDRLAWAISQAANTPSMQHNAQAMAKTLQAEQGISRAVEIIEQRIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZW8</accession>
    <name>A9AZW8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metalloenzyme domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphopentomutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4541"/>
    <dbReference type="EnsemblBacteria" id="ABX07172">
        <property type="protein sequence ID" value="ABX07172"/>
        <property type="gene ID" value="Haur_4541"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4541"/>
    <dbReference type="eggNOG" id="COG0696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079842_0_0_0"/>
    <dbReference type="OMA" id="FHINGQI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4596-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043094">
        <property type="term" value="P:cellular metabolic compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010045">
        <property type="entry name" value="DeoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21110">
        <property type="entry name" value="PTHR21110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="5">
        <location>
            <begin position="2"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="32188" checksum="ED7F1961DEA8405E" modified="2008-01-15" version="1">MSVIVCFIDGVGLLPHAAAPWTTAHLPTLTNLLGDLPHSNLQIEQPNLYFRAIDATLGVEGLPQSGTGHTSLWTGVNASALLGRHYPAYPAPSQRPMIAEQSLFAKVQQLGRTSLIATVHRDRYWELVAKREQRATAAALAAQVVDLNLPATPEWLAGQAVTWDITGYYLQQWGALAGLPTITAHEAGLRLGQALRLADLVHYECYLPDFVGHRRIVETPEHTLELIDTMLGAIISQMQPSDSLILVSDHGNLEMIEHTSHSRNPVPLLVVGAKAQAAAKVEDISQITPLILDLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZZ9</accession>
    <name>A9AZZ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1058"/>
    <dbReference type="EnsemblBacteria" id="ABX03706">
        <property type="protein sequence ID" value="ABX03706"/>
        <property type="gene ID" value="Haur_1058"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1058"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1093136_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1075-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="28823" checksum="561F53EED695947D" modified="2008-01-15" version="1">MNNNDWYRYFAPRQVATLSAERQHADYAAAQHDLDFVLAQISIGSKASILEIGCGWGRHSVVLAERGFAQVLSIDIAPELLQAAQAFAQQRDQTCQFRQQDFIELREQPFDAIFSLYDRSCCGYPSEAADAQSLQHLANLLQPNGWLIFGINDWPFALPEASQRWAETEQGLELYEVIPDRRAMTCTDRLTVLNAGQRTSYELMRRHYYLPELQRLLGNAGLRLVSAWHRLDIQRPYGDGSNGLFIVAQRASNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B041</accession>
    <name>A9B041_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPK2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1100"/>
    <dbReference type="EnsemblBacteria" id="ABX03748">
        <property type="protein sequence ID" value="ABX03748"/>
        <property type="gene ID" value="Haur_1100"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1100"/>
    <dbReference type="eggNOG" id="COG2326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048699_3_1_0"/>
    <dbReference type="OMA" id="NPRICRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1120-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPK2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="33645" checksum="E5F251EC527774DB" modified="2008-01-15" version="1">MSLLDHVDLSLDLGKKSYERQLTDLQFKMLRLQRAVTQIGHRMVLVFEGWDASGKGGVIKRLTEALDPRGFVVHPIAAPTPEERAHNYLWRFWNRLPRDGQIVLFDRSWYGRVLVERVEGFATMREWSQAYGEINDFERILHNDRTSVLKFFLHISSDEQEKRFRERENDPLKTWKLTEEDWRNREKWSEYAIAIDEMLARTSSENAPWQVIAANDKRWARIAILKAVVEMLVADMPFEFDDANTLVLDRSGAYALVDAGKLSAKAVEAVIAEEEKVRKLLKKQRKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J3</accession>
    <name>A9B0J3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein, MarR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4580"/>
    <dbReference type="EnsemblBacteria" id="ABX07211">
        <property type="protein sequence ID" value="ABX07211"/>
        <property type="gene ID" value="Haur_4580"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4580"/>
    <dbReference type="eggNOG" id="COG1510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120349_2_1_0"/>
    <dbReference type="OMA" id="TLAFFEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4635-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17936" checksum="ED72556605E7C102" modified="2008-01-15" version="1">MAMDNLQARLAYAERIAVFYEKAGGIPRMAGRIMGWLLICDPPQQNAAELGQVLSASKGSISTMTRWLLQIGLINKTAVPGDRRDYFEIRKGTWADLLAQQFQTVGAFRELATQGLDLLTDPEGEEGARLREMRDLYTFFERELPLLIEKWRNERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K4</accession>
    <name>A9B0K4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4591"/>
    <dbReference type="EnsemblBacteria" id="ABX07222">
        <property type="protein sequence ID" value="ABX07222"/>
        <property type="gene ID" value="Haur_4591"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4591"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_0"/>
    <dbReference type="OMA" id="APYWTTY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4646-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="30"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="42339" checksum="7A1790253C152285" modified="2008-01-15" version="1">MTRERLSARVQSVPPSGIRRFFDIAATMDNVISLGIGEPDFVTPYTITQAGIRSLQQGKTAYTSNSGTIELRQELQKHLNHLYGLNYDPENELLITVGVSEALQNAMLATIDPGDEVIIPEPCFVAYGPSVVFAGGVPVYVSTSVEQEFQVTREAIEAAITPKTKAILIGYPNNPTGAVMSRERLLDIAALAEQYDLLVFSDEIYDRLVYGVEHTSFAQLPGMRDRTILLGGFSKAYAMTGWRLGWLAASAEIANAVRKIHQYAIMSAPTVAQYAGLAALQTGEEDVQRMVSEYDRRRQVIVAGLRQIGLPTFEPQGAFYVFPQVSSLGLTSEAFVEGLLYREKVAVVPGDAFGPSGAGFVRMCYATSMDNIETALERIERYVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K5</accession>
    <name>A9B0K5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4592"/>
    <dbReference type="EnsemblBacteria" id="ABX07223">
        <property type="protein sequence ID" value="ABX07223"/>
        <property type="gene ID" value="Haur_4592"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4592"/>
    <dbReference type="HOGENOM" id="CLU_2422919_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4647-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="91" mass="10166" checksum="6EA5DEC437B8CE33" modified="2008-01-15" version="1">MSSESSVECTRCKRQLKADEVRMAQPLITFKELVRAAIKTPSLLNAKLEDVPYCPECRGIIAKQRQTEQLKFLAVVVAVLLILIVLVVVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N5</accession>
    <name>A9B0N5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="9" type="ordered locus">Haur_4622</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4622"/>
    <dbReference type="EnsemblBacteria" id="ABX07253">
        <property type="protein sequence ID" value="ABX07253"/>
        <property type="gene ID" value="Haur_4622"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4622"/>
    <dbReference type="eggNOG" id="COG0541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_0_0"/>
    <dbReference type="OMA" id="DTAGRHK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="109"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="249"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="449" mass="50314" checksum="95F22CEE406FCCF8" modified="2008-01-15" version="1">MFENLSDRLTDVFNRLGSKGRLTESDVDAGLREVRLALLEADVNFKVVKDFVARVREQAIGEEVTKSLTPGQQVIKIVHDELVHLLGDANVPINESKNREQPTIVMLVGLQGAGKTTMAAKLALYMRKKGKTPLLVAADIYRPAAIKQLETLGKQLNIPVYSEGTEVAPPDIAEHALRQARINGNNFVIVDTAGRLQIDERLMTELQQVVERIGPTEIMLVVDAMIGQESVKVAEAFHAKVPLTGLIMTKIDGDARGGAALSMREVTGVPIKFLGTGEKTDAIEPFHPDRLAQRILGMGDVMTLIERAEQVYDKDEAKKMQKKMRKGTFDFEDFLGAMNSMRKLGPIQQILGMIPGLGKQMRQMKELDEALDDREMKRIEAIIQSMTIKERRNPDLLKDPSRKRRISVGSGTRIEDVNALVKQFREMQRMMKRFSKGGQNPRDLMRMFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Q1</accession>
    <name>A9B0Q1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Selenocysteine-specific elongation factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">SelB translation factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1123"/>
    <dbReference type="EnsemblBacteria" id="ABX03771">
        <property type="protein sequence ID" value="ABX03771"/>
        <property type="gene ID" value="Haur_1123"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1123"/>
    <dbReference type="eggNOG" id="COG3276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023030_3_0_0"/>
    <dbReference type="OMA" id="YAIDRVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1144-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015190">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09106">
        <property type="entry name" value="SelB-wing_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="627" mass="69325" checksum="6641EEC6BF6AFD9C" modified="2008-01-15" version="1">MAITLGTAGHVDHGKSSLVQALTGINPDRWEEEQRRQMTLDLGFAWFSTPAGHSVNLVDVPGHERLIKNMLAGVTGFDGVLFVVAADEGMQPQSHEHLQILNQLGIEHGLIIISKIDLVDAEWLEFISGDIQAQFAATSLANAPIVPVSARTGAGMAQLLQALDQLISQLPARTIQKQHPHLPIDRVFSIDGFGTVVTGTLRDGNLSVGMEIEILPQQLRGRIRGLQSQQISYVSVQAGMRVAVNLSGIERQSLKRGDVLTLPQTFEPTNLLDVLIETTTAAPSLSHNQPLQLYLGSAELSCTLALLDCDTLPAKQQAFGQLRLQHPTIAQRGDRGILRRASPAATVAGIRVLDAHPQRHRRMRPAVIEQLQQLANGLPHEILLQHIQQQCLTWQELQQRSGFDSPTALAALNIGCNNGLISIVSATMATLTASSLITSTAYWSQLQANLRQILAEYHAMWPLRTAMPREELRKRMGLAANSFNQILNALAAQPWLSVEATQIKLTEHQAQPSPGQQAQIQALLGLWQSNPALPPSREQWPKLDPELWRYLLQTEQLIQIGAEVYFLPKQYHQMHTWVLEQLAAGQSISLAQARDAWQTSRKYAQAMLEHCDQLRITRRVGDLRVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V4</accession>
    <name>A9B0V4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1176"/>
    <dbReference type="EnsemblBacteria" id="ABX03824">
        <property type="protein sequence ID" value="ABX03824"/>
        <property type="gene ID" value="Haur_1176"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1176"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118578_0_0_0"/>
    <dbReference type="OMA" id="CYDTTAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1198-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="16559" checksum="AF631AF3E5A73988" modified="2008-01-15" version="1">MPDLLVKLYELPTIPSIAGVTIRRALAPERHVVLDWVARFFYPAWRSECAVAFSQSPISCIIAVEEQKLLGFACYDTTTRNFFGPTGVDPDCRGRGVGTALLVAALDAMKQLGYGYAIVGDAGPVEFYQRTVGAIVIPDSTPGVYRGMLQGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y1</accession>
    <name>A9B0Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.157" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1203"/>
    <dbReference type="EnsemblBacteria" id="ABX03851">
        <property type="protein sequence ID" value="ABX03851"/>
        <property type="gene ID" value="Haur_1203"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1203"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_0"/>
    <dbReference type="OMA" id="RDNCLTH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1225-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="3">
        <location>
            <begin position="186"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="30628" checksum="9BDA7B3DA4563CC5" modified="2008-01-15" version="1">MAITKVGVLGCGLMGAGIAQVAAQAGFMTVVREVNQAVLDKGLDRINAILEKDVSKGKLSAADRDASLARLYGTTSFEDLADCDLIIEAIVEQLPAKREVFTALDELCPPSTIFVSNTSSLTIMEMAAVTKRPDRFAGLHFFNPVPVMKLVEIVRALTTSDETIASLHEFTRALGKTPINTSDTTGFIVNRLLVPFLLDAVRLLESGVATREDIDEGMKLGCGHPMGPLTLLDFVGIDTVYSIANIMFDEFREPRFAPPPLLRRMVLAGHFGRKSGQGFYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B112</accession>
    <name>A9B112_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2652"/>
    <dbReference type="EnsemblBacteria" id="ABX05290">
        <property type="protein sequence ID" value="ABX05290"/>
        <property type="gene ID" value="Haur_2652"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2652"/>
    <dbReference type="HOGENOM" id="CLU_1624855_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2682-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="18643" checksum="114EBEE5BE431760" modified="2008-01-15" version="1">MLDQPLNDIFTGWAAMTEHNSDLVADRFGMPRAELDELVHGSVAHLAQTHYYHYLARPKPQFDDDSDENTAAQSKPRHVVLFRTPDDALSFAQRIRIGETPRVRQISRENMIWHMLNDEAIVRVIFFEQPLEELPTGLNLQTLADLPGAIAIERNDVLTSRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J6</accession>
    <name>A9B1J6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1233"/>
    <dbReference type="EnsemblBacteria" id="ABX03881">
        <property type="protein sequence ID" value="ABX03881"/>
        <property type="gene ID" value="Haur_1233"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1233"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1255-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="37879" checksum="AB2B1E71E4DC8E1D" modified="2008-01-15" version="1">MSYLQLDQLTKSYAQQTILQNINLNLNQGEFLALLGPSGSGKSTILKLLAGIEAADAGEMRLAERLLNPVPAHQREIVLLFQQPYLFPFLSVAENIGFGLKARKEPKKLIQQKVAELLELVELGGMQQRKPQQLSGGQQQRVALARALAVQPKVLLLDEPLSSLDPEIRVNLQGVIARLHRELHMTTIIVTHDLSEALALAQRTALLINGEIIADLNSIELFERPPNRAAAQFVGVGAIIVGHMQGPTFCSSLGQFNGNFAPNTRHVAIRPEHIQINDQPQPQTIAAQIIERRYLGERWEYRLQTNEQIVVARETVQAIREIGQTVYLHFPQQSIFALND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1M1</accession>
    <name>A9B1M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative sensor with HAMP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1258"/>
    <dbReference type="EnsemblBacteria" id="ABX03906">
        <property type="protein sequence ID" value="ABX03906"/>
        <property type="gene ID" value="Haur_1258"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1258"/>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_777956_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1280-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="247"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="39379" checksum="CAFB67BE41B4903D" modified="2008-01-15" version="1">MTAVAPKSRFLSLRWRLLAIFTLLFFIVLTGVFVWFLNYATDNAQADLEADLMAIAKTAAAGIDGDEHSALYSQGQIDDPTYLKINAYLREVKTTNPKASGIYTFVQLPNEPDQARFVVSAAIPPGQSETAREKELLTESTYGCTINRTTRPLMNANFTSAGGFSAAMARGLREPSIDPKPSVDQWGEWIAGAAPIYNAKGETVGAVGVDMCVAEVTAVRNRISQTLIPGFLIVTVLLAIAIYLIAHRLTKPIIGLTAVAKQISNGDYSSEVPESTSRLRDEVATLASVFAMMVDKVREREHKLRQQVAELQIIVDEGKRKQQVDEIVDSEFFRNLQEKAREARQRRDRRPPDQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q7</accession>
    <name>A9B1Q7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1294"/>
    <dbReference type="EnsemblBacteria" id="ABX03942">
        <property type="protein sequence ID" value="ABX03942"/>
        <property type="gene ID" value="Haur_1294"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1294"/>
    <dbReference type="eggNOG" id="ENOG5033PAQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149392_0_0_0"/>
    <dbReference type="OMA" id="MAFIVNT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1316-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="16264" checksum="278167240E022516" modified="2008-01-15" version="1">MPTLARYYIRTAFVWLVLAFGLGSAMLTSQLWGFKTNPLAALQIVFYHALMVGWVTQLIVGVAIWLFPVHTREQPRGNERIAWAAYITFNLGLGLRSVVEPMLQWQPSTVVSWAVVVAASLQVGALWLILLMLWPRVKGKAVKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1U0</accession>
    <name>A9B1U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase, WecB/TagA/CpsF family</fullName>
            <ecNumber evidence="1">2.4.1.187</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.187" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2744"/>
    <dbReference type="CAZy" id="GT26">
        <property type="family name" value="Glycosyltransferase Family 26"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05382">
        <property type="protein sequence ID" value="ABX05382"/>
        <property type="gene ID" value="Haur_2744"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2744"/>
    <dbReference type="eggNOG" id="COG1922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063203_3_1_0"/>
    <dbReference type="OMA" id="PWRWRRM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2775-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047244">
        <property type="term" value="F:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="27995" checksum="C02B012372333811" modified="2008-01-15" version="1">MTFQRPANLASLEILRVRVDDVTMDETIELIAAMLAAGGAHQIATVNPEFVMAAQDNVAFRATLAATSLAVPDGTGLLHAARWQGKQLRSKVTGIDLTERLAAESAQRGWKIFLLGAADGVAAKAAAVLQQRYPNCQIVGTWAGSPREPDQPVIANEIRRSQPDIVLVAYGAPAQDLWIRRYGAGLGIKLGIGVGGTFDDLAGLRPRAPQWMRKFGLEWLWRLIRHPERWRRIFTAVVLFGWAAWREAQRIKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W7</accession>
    <name>A9B1W7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2771"/>
    <dbReference type="EnsemblBacteria" id="ABX05409">
        <property type="protein sequence ID" value="ABX05409"/>
        <property type="gene ID" value="Haur_2771"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2771"/>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010363_0_1_0"/>
    <dbReference type="OMA" id="TNTQTFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2802-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="122"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="39950" checksum="0DA8D32CBAD032E2" modified="2008-01-15" version="1">MTAPSFPAFCNRCGNRRSPQARFCRYCGNAFQHWQATATKSIPSTEVGVKAVQRSIKWRYWFALTLVLFIGARLSLKPLMGLVLGGLNFSNAPIAGTPNQSPPNQRLATGQTLRIHVIDVDQGDSILIQTPQGMNALIDGGYDNGLALEYLHQQGIQRIDHMIVSHPHADHIGGLVEVLNSLEVGSIWTSGAVHSTSYFENLLDAIDRQQVPYREVKTQESIPLGDLSLLVVRSEPQAGDLNDTSLILRLEYGQFSMLFTGDAEASSEVDVLQTTPNLLPATVLKVGHHGSYTSTTPAFALAVDPTLAIYSAGRNNSYGHPHQQTLTTLCNLGATVYGTDRHGTVVITSDGLEYQVQTAQRTTALCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X7</accession>
    <name>A9B1X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2781"/>
    <dbReference type="EnsemblBacteria" id="ABX05419">
        <property type="protein sequence ID" value="ABX05419"/>
        <property type="gene ID" value="Haur_2781"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2781"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074977_0_0_0"/>
    <dbReference type="OMA" id="PAWNLLP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2812-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="39"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="33239" checksum="4F4AB07063E0B8D9" modified="2008-01-15" version="1">MIRLLMHPNEQPIDHALVQSLLASQFPEWVGLPLQKVDSAGTDNAIYRLGSELAVRLPRIDWAVDQIASDFRWLSWLQAQLPLQIPQPIAQGQPTANYPWPWGIYAWLAGENAINARPNNPEHGLSQFLHALQKIDAQTGPAPASPTARGVSLIQRNAVTRAAITQAHTLLDTEQILAVWDHAIQIETWAYAPVWIHGDLHAGNLLVIDSNLSAVIDFGALAVGDPACDLLPAWNMFDRQTRLNFRQAMAVDAATWIRGRGWALSVAVIALPYYHQSNPVLAQMARYSIQQVLDDWNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y0</accession>
    <name>A9B1Y0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05422">
        <property type="protein sequence ID" value="ABX05422"/>
        <property type="gene ID" value="Haur_2784"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2784"/>
    <dbReference type="HOGENOM" id="CLU_2023529_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2815-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="14059" checksum="8514F659CA13D90F" modified="2008-01-15" version="1">MRAASMAKSIMIIARTAAIPFIAEELTEHGYFPYCCDSIQLALDTVYQLNPDLILIIDHFIEGFRDPLEIYFYTRQHLNQAVPVIFVSFRHIPETLAQLDLDCFTLLEMEIAMNTIYQLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B275</accession>
    <name>A9B275_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stage V sporulation protein S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4794"/>
    <dbReference type="EnsemblBacteria" id="ABX07425">
        <property type="protein sequence ID" value="ABX07425"/>
        <property type="gene ID" value="Haur_4794"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4794"/>
    <dbReference type="eggNOG" id="COG2359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168904_0_0_0"/>
    <dbReference type="OMA" id="IGIEIAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4852-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007347">
        <property type="entry name" value="SpoVS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35331">
        <property type="entry name" value="PTHR35331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04232">
        <property type="entry name" value="SpoVS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="12221" checksum="7A533F415ADB3292" modified="2008-01-15" version="1">MAYQLDRFSNDDQRTTSADAPSNAGAVHNDAEVLKVSTRSRPSAVAGAIAGVIREAGHAEVQSIGAGATNQAIKAVAIARSYLQEEGIDIVCVPSFIDVAIDEEERTAIRLLIKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A2</accession>
    <name>A9B2A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4822"/>
    <dbReference type="EnsemblBacteria" id="ABX07452">
        <property type="protein sequence ID" value="ABX07452"/>
        <property type="gene ID" value="Haur_4822"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4822"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_0_2_0"/>
    <dbReference type="OMA" id="PFLTHQL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4881-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="34386" checksum="7E59A115AEA29684" modified="2008-01-15" version="1">MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQFLAAYGDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGAYVFEPAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHLPHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAAANLNNVAIANDVQVAHHATVEGLALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D5</accession>
    <name>A9B2D5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1335"/>
    <dbReference type="EnsemblBacteria" id="ABX03980">
        <property type="protein sequence ID" value="ABX03980"/>
        <property type="gene ID" value="Haur_1335"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1335"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_865368_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1356-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="265"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="35926" checksum="B8C6223D42B3F0B3" modified="2008-01-15" version="1">MPVCTRCHQDTGLMGALRFNRQTNRCGPCDGVVQQQLQRFRQAFLQFCNDGLLSPQEWTILIQGSQQEGLSWDEALNYIRGDALNFLERTLAFASTDGVITNEEAAHIQQLQQAFRIPDHQAQPLLQRLKYLQTISNVRQGHLPTIQPTVRLDAGEICHLETDARYHKVTAKGTTLQPGRFVATNKKLHFLSQAGGSSIDWKKVMRINAEAGSIYLELSVKSGNGRYSVADPTMAEAVFDVLVRMAKREFIAPQTGQESRYIPQDVKLAVWQRDQGKCTQCGDASYLEFDHIIPHSKGGANTVGNVQLLCRKCNLAKGDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G5</accession>
    <name>A9B2G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="16527">
        <property type="entry name" value="HauORF1365P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04010">
        <property type="protein sequence ID" value="ABX04010"/>
        <property type="gene ID" value="Haur_1365"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1365"/>
    <dbReference type="eggNOG" id="COG1002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005831_1_1_0"/>
    <dbReference type="OMA" id="HKLGAHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1386-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="925" mass="104770" checksum="874948CEAE886DE1" modified="2008-01-15" version="1">MQPLEFVRKWRGIQVNERRAYYEHFTDLCSLVGAKTPLEEDPTGTFYTFEAGVTKLNGGKGWADVWKKGYFAIEYKGKHGNLNRAYDQLLQYREALLNPPLLIVSDLDSLVIHTNFTNTVKKVTTLTLDETLTRNGLDTIRSIFYAPDTFRSPVTPERVTEEVAAKFARLAQLITRYEKHTSPQEIAHFLTRLLFCLFAEDVNLLPKDIFSRLVTQTRGKSSAFAAQLSQLFNVMTTGGWFGIEEIRHFNGSLFDNATVLPMDSEALDILVDICSYDWSSIEPAIFGTLFERSLDPAKRKQLGAHYTSKDDILLLVEPVVIQPLREEWSKQEQVIEGLVTQRNETVGNDVTKINRQIEFHINTFLHKLRSIKVLDPACGSGNFLYIALKLLLDLEKDVIRFGADAGLPLQIPQVNPEQFLGMEVNAYAHELAQITIWIGYIQWMKENGFGNLSEPILKSLKTIHRMDAILAFDADGNSIEPAWPQADYIIGNPPFLGGNKIRQELGDGYVDALFSRYADRVPAFADLVCYWFEKARAMIGSDITRRAGFIATNSIRGGSNRKVLERIKTSGDIFMGWSDRPWILNGAAVRVSMVGFDKGEEIIHSLNGMIVQSINANLTQDIDTTKALILPENKNIIFGGTKKGGKFDITQGIYDVLMQSQNNPHGRPNSDVIKPWVNGQALLGKGEKRWVIDFGVDMSLEDASQYEKIFEYIKKEVYPIRINNRMESRSKHWWLHSFTAPSMRHAVATISRYIATPRVSKYRLFVWVDSNTIPDDGTYIVARDDDYFMGVLHSKIHELWALRQGTFLGVGNDPRYTPTSTFETFPFPWPPAKEPKDSPLVNAIAEAAKELVEKRDRWLNPAGATEADLKKRTLTNLYNERPTWLDLAHKKLDKAVFAAYGWPDTLTDDEILGPLLVLNHDRAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K4</accession>
    <name>A9B2K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    <dbReference type="OMA" id="PKGVEHC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2848-MON"/>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
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    <dbReference type="Pfam" id="PF07883">
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            <end position="93"/>
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    </feature>
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        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="14077" checksum="2EF1A448F2DF9992" modified="2008-01-15" version="1">MSTVINLVEKFGHFNDYCNPRVVGELNGQQVKLVKLQGAFEWHHHEHEDELFFVVQGRLRMQLRDGDQVLNPGEMIIVPRCVEHCPVAETKEVWLMLFEPATTLNTGNLQNERTRTELEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N8</accession>
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        <submittedName>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2851"/>
    <dbReference type="EnsemblBacteria" id="ABX05489">
        <property type="protein sequence ID" value="ABX05489"/>
        <property type="gene ID" value="Haur_2851"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2851"/>
    <dbReference type="HOGENOM" id="CLU_2682782_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2882-MON"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="74" mass="8442" checksum="C37B624971D90A73" modified="2008-01-15" version="1">MLEYLIAYAPVQGDAPCAAEAREWPDRAAMDAQLLAEGWQLIESAEYRAAMLKLVYQRDLAHQPEAPRHLMPCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P8</accession>
    <name>A9B2P8_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05499.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX05499">
        <property type="protein sequence ID" value="ABX05499"/>
        <property type="gene ID" value="Haur_2861"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2861"/>
    <dbReference type="HOGENOM" id="CLU_993133_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2892-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="280" mass="30400" checksum="5852E25F1AD72A7D" modified="2008-01-15" version="1">MDTQTQPFWQRFGIHTLSLGLGGAIASLVSLLLGNIIFGRSSRVLTGGMPVFLVIMMVIVGCVSYFIIKRWFRGCSSFLVIGGWFLAHFVVNVIAVVFFDSDMSIVSYVITWLIMGALGALMFSNSTFARSIGMVGAGTAIGAGVYAASRNNEVLKASGYGRIPPSTVILLTQHVRFANDAVNQLPANAPANIRKIAVNVVLEHVIRDWWSNGNNEGLTPADVNDLGAFVQLAWFAARGQSHLLQAEAVFRASLIALMDDWFNSWNAEGVEGAPRWQSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B311</accession>
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        <submittedName>
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    <organism evidence="13 14">
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    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
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    <comment type="subunit">
        <text evidence="8">Homohexamer. Forms a ring that surrounds DNA.</text>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABX07474.1"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="13" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="12">
        <location>
            <begin position="477"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="273"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="802"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="495"/>
            <end position="502"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX07474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="824" mass="89953" checksum="9257042E686C4835" modified="2008-01-15" version="1">MSTRKSAPKRQSGKKPTAATARKRGAAKQTITPQIQIPQNLQREIFAVILVFLGLLTLLFSTFSGDQGVIGTQWNTAVARAFGTGKVLVPVALGILGGLMIFQERFSDSRLSGANILGTLMVLLSLLMLLEYPGYEIHREHPEFHVGAGGGVVGQTLLTILISGIGKGGALLFSVTIGLIGIMLTFNLTLRQIMAALFYYTGGLRILGRRLLGSPVRREPMFDDYPEEHFRPLELPAPQAMPKVSNKRRQAILEDTTNQEVVLTPIAERPAQASLFNRDLPEPNRPARRKEVAPPPVAPNAAGSMAPTKRLKPADDQTKSNQPNANAEDPNFIEPDEALTHRAWPLPTLNALDEFVEGQIGDEEKREKARIIEETLASFRVEARVVEANTGPAVTQFALQPAIGVKINKITSLQNDLALALAAPSLRIEAPVPGRSVVGIEIPNSAIATVAMRDVIGSEEFDTKRGKLKIPLGKDVSGNVVIADLAKMPHLLVAGSTGSGKSICINSIIISLLMKHTPNELKFIMVDPKMVELIVYNNIPHLLTPVVTELERVVSSLKWAVREMERRYKVFAKGGFRNLESYMQAARKRPDLEPMPYIVVIIDELADLMMLAPDEVETLICRLAQMARATGIHLILATQRPSVDVVTGLIKANFPTRIAFAVTSQIDSRVILDTPGAEQLLGRGDMLYLAVDAAKSIRVQGTFVSDGEVEKVVQFWRMQIPPELTKPDAANPQAKPAPSSQTSMGDVFLQADEQDELLPKAIELVRQHQRASASMLQRRLRIGYSKAAQLIELLEQRGIVGPAEGSRSREVLNPEQGAKAGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E7</accession>
    <name>A9B3E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1466"/>
    <dbReference type="EnsemblBacteria" id="ABX04110">
        <property type="protein sequence ID" value="ABX04110"/>
        <property type="gene ID" value="Haur_1466"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1466"/>
    <dbReference type="eggNOG" id="COG3263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_9_2_0"/>
    <dbReference type="OMA" id="QIGMFVL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1488-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="401"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="487" mass="52391" checksum="C6DF28746B2AB594" modified="2008-01-15" version="1">MSTESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQVVGIVALIYILFSGGLETHWHRIRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGLLLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSNDPIAVFLTIGLTSYLTSSGHSVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVHGNGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKGLLLAIFLMFIARPISVIVALGWTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQANDMFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMPLDFIPEISPESTVYEVVVPDDARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRLNIANQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R3</accession>
    <name>A9B3R3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2997"/>
    <dbReference type="EnsemblBacteria" id="ABX05635">
        <property type="protein sequence ID" value="ABX05635"/>
        <property type="gene ID" value="Haur_2997"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2997"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="MESTCHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3029-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="30"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="150" mass="17123" checksum="CDBF451D40C60CBB" modified="2008-01-15" version="1">MRLRDWTQEPDLCEVFKSIHITGVLQIMQHIVVVDDTPALAELVMRMLTRYGYHVRTLSGGLQLIEYMRQHRPALVLLDVGLPVKDGWTLIREIRMQPDLAHIPVIAVTAHAADEDRQRAFSAGYTNYLSKPFDVQDLLQMVRGYVPSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U4</accession>
    <name>A9B3U4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3444"/>
    <dbReference type="EnsemblBacteria" id="ABX06080">
        <property type="protein sequence ID" value="ABX06080"/>
        <property type="gene ID" value="Haur_3444"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3444"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_1_0"/>
    <dbReference type="OMA" id="TITFAEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3481-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="4"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20570" checksum="7E576ED63F1D3401" modified="2008-01-15" version="1">MSIKSIGILIFNDAEELDFIGPLEVFGMASNWVDLTINTVAEQTQTVKARYGLKIQPDYSFADAPAFDVVLVPGGIGARTHARHNSLILDYLRQQQQRGWVVSVCTGALVLSAAGLLDGKQATTHYTALDLLAENSQITVERQQRYTITPPIATSAGVSAGIDLALALLETWFSPELRAQVAERIEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B413</accession>
    <name>A9B413_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ordered locus">Haur_4916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4916"/>
    <dbReference type="EnsemblBacteria" id="ABX07546">
        <property type="protein sequence ID" value="ABX07546"/>
        <property type="gene ID" value="Haur_4916"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4916"/>
    <dbReference type="eggNOG" id="COG0088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_2_0"/>
    <dbReference type="OMA" id="PQVHILE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="22919" checksum="55B4C30C9BCEACEF" modified="2008-01-15" version="1">MEAKLYNQAGQAIGTLELQDYIFGIEPNIPVMHQAVIRQLANARLGTHSTKTRGEVRGSTRKLYRQKGTGRARQGAIRAPHHSGGGVVHGPKPRKYTKAMPRKMRRLAVRSALSAKYAENQIIFLDDLSLNAPKTKDFLALLKNLPLVGDKTLVALGEKSDNITLSASNLPNVKTLLAAYLNVRDLLTYDTLILPKSALSVVETILGKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-22" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B461</accession>
    <name>RS18_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsR</name>
        <name type="ordered locus">Haur_4964</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B461"/>
    <dbReference type="SMR" id="A9B461"/>
    <dbReference type="STRING" id="316274.Haur_4964"/>
    <dbReference type="EnsemblBacteria" id="ABX07594">
        <property type="protein sequence ID" value="ABX07594"/>
        <property type="gene ID" value="Haur_4964"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4964"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_2_2_0"/>
    <dbReference type="OMA" id="CKDKATY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000345485" description="30S ribosomal protein S18">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <sequence length="86" mass="10072" checksum="91499C6908031FC0" modified="2008-01-15" version="1">MSDQRRKSAGRRKYTPRRKVCVFTAEGIVPDYKDIKRLQRMVSDRGKILPRRRTGTCAKYQRKLNVAIKRARHLALLPFVSENTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E0</accession>
    <name>A9B4E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0045"/>
    <dbReference type="EnsemblBacteria" id="ABX02697">
        <property type="protein sequence ID" value="ABX02697"/>
        <property type="gene ID" value="Haur_0045"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0045"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_272949_0_0_0"/>
    <dbReference type="OMA" id="ANISWIQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-45-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735442" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1012" mass="111781" checksum="8D037468AB5A2C6A" modified="2008-01-15" version="1">MRRFSKVRLLGICVLLLSLTAYQRTPNSSAQVLRSLVPVPEVESNDTWQNAHDLTSSCLWPSITICDVTGELDDGEDLDWYKITVRPATTLSISLTDTFGDYQVALFYDLAKPITQTGHVSLGNLNAIGNLNAIGNLNAIGNLNAIGNLNAIGNLNAIGNLNAIGNLNAIGSNGYSDASIDSFLWTPGFYYVLVYPLDEDQSGDYNLAIEATFDQNLTKPLPIPFMINQSEPPDCKRSLYITNSDYFNIYEAFAPYNTSVYTELLGLASKPGDTSGLVLDLANISWIQPSNAFSDQSTQWDNNRNNPFYANRIAEGVHHLITQYARRCASLRYVTIVGGDYVVPFYRVPDETVIANEGDYLASSGINTNSFTASSLKYKTILTDNIYGAIKPIPYRGRQLWVPELSVGRLVEGADAIHLYLKSMNLHTDFPSGSMINLNPQPQQANLVTGYDFLLDQAKVISGTLTNLVGARPVGLISDTWDADDLLSIWWPDVNNGMSNSPYPAQSINAHFTHYQAIPANFETSTDVVEAKVLFQHPFSPVALEDAYQRNRLGYSVGCHSGYSVYDNDVAGGLTNPVAIDFPQAYMKQHGAWIGNTGFGYGDSDLVGYSEKLMAQFTLEIGREWKNQSGFYGGMPIGYALVRAKRSYLREGTPGTFSVYDEKVLLQSTLYGLPMIRVLVPNPIPFPPNDRQDFACLTCPPSVAHRATVTDRAIDRDITFNINYTTAQDNARGKILRAQATVVNDTEGLLTGQMFNSSLVNAAGLPSLPNFSIPLSLTDGFGEQRIQGIQFLGGTTTTAATFNPVITRLITDEIYLSHEPTFDFTDRWYPDQPFSYSVFESDNLDDDGPLNQDRRFSQLLLTPTQFKGNTSGGELRQFSTITLRLKYLSDGADDDLLDDTFDPIVRDTQRTSDGKIRAIVIERDNDGPGDELDAEMVVKTNTGAWQTVSMNTFQIGTTERWQIEGSLPANTFLPLQLLIQAEDEAGNVGVETYGGRFDIDYEMYLPNVNVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4F8</accession>
    <name>A9B4F8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="11" type="ordered locus">Haur_0063</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0063"/>
    <dbReference type="EnsemblBacteria" id="ABX02715">
        <property type="protein sequence ID" value="ABX02715"/>
        <property type="gene ID" value="Haur_0063"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0063"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_3_2_0"/>
    <dbReference type="OMA" id="HIECFDN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="9">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="10">
        <location>
            <begin position="266"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX02715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="641" mass="72067" checksum="8B6F0A1E9FFB3E0D" modified="2008-01-15" version="1">MPDLSHTNIANHALFEERLRNLPLSPGVYIYRDQANTIIYVGKSKSLRDRVRSYFGAPRGLTSKTRRLVQNIADFEFITTDTELEALLLEMNLIKKHRPRYNVLLKDDKSYPYIKITKEAWPRVLRVRKVIEDGGIYFGPFAKASSVYATIELLNKLFAFRLCNDDMFKKHERRNRACMYYDIKRCLGPCANNCTTEEYSTAINQVRLFLGGKPEAILRDLKVKMNQAAEDLQFERAAYVRDQIKAVERVMERQKVLNTAASDQDVIAFARDEGKAVVQVFYIRGGKLIGSEPFTLQGTEEEHPEALMSSFLTQFYDAAADIPPNILLPDYPEETQIIEQWLESKGGHKVSLQVPRRGDKKDLVDLAARNASQTLDQLRLQWLNAEQRATAGLSQLRELLNLAELPQRIECYDISNTQGTNSVGSMVVFEQGEPAKKHYRRFKIKTVEGANDVASLSEVLQRRFARADDTGQTDEPESTEQTSAEPTNNDETWAVLPDLILIDGGIGQVNAAAKTLAAAGFEHIPVVGLVKGDTKGHLPYGLVKPGQRVPIAFAQNDPGLHLVQRIDEEAHRFAISYHRKLRTKGMLRSTMEDIPGIGPKRKKALINAFGSLEGIRNASIEELAAVPGMTRKAAEEIKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4L4</accession>
    <name>A9B4L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1535"/>
    <dbReference type="EnsemblBacteria" id="ABX04179">
        <property type="protein sequence ID" value="ABX04179"/>
        <property type="gene ID" value="Haur_1535"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1535"/>
    <dbReference type="HOGENOM" id="CLU_406409_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1559-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="676" mass="72791" checksum="70FEBF73E9C5ED23" modified="2008-01-15" version="1">MSTPHAQVYFNRYNLFNTTPNPAPSGNTDWYTNQPIMQLSNPQLTQRVPSQTALLTNWSLPNANLLGLQDLNWAFCVYDLQQQLATSANADDLPNAPLAYAQVQATHNTTQSTIATKVCLFNVLVAIEWVPSAIELNQLQWAFRRASDFLFDVSNGTMAFGQVVFGGVQHMRAADIQILASNRYHPRSWREGLYTDAKHMPIRLGRGMWERQGSFSIPWHEPEGYRVIVHEWMHYAIGLRDQYINSNNAEHPDLALPSFNPTAESIMAHLVGSSEVMRIEGGDDVWQPFRAQTGAGLPYSAMATAPFDQPRVGPERLPLPLPLFQHSFGSNPTAEVINLPIAETPLAGLKHGWVYVLRGSLNDPSTIIPQGSLDSRVNSQGFKLLGANSDDYVVVIGDQANGSTAVYVAQLEGNPPECNWLECTPSQFPLVAVMPYGSVTQGSYSVKVVTESGLTPTAIYVAAAGEQNAYAVDVNGVVSNLPSLDGTALLVFEGQTGIQLAVAAYSEGGNPPSHNPTAPIPLTAGSSEGNLMVFFNQAAESRASELNHLRVITTTMYGSCSNLPNATGGALSRGYIFALASNAALPSDVGASVPLKPTLVLNYDNAALLSLGTTAGIAGVLQVYSANGATPQAEASKHFVDRGYVALALNATSASGLFASNPTPEFFRLYGQQFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T0</accession>
    <name>A9B4T0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3015"/>
    <dbReference type="EnsemblBacteria" id="ABX05653">
        <property type="protein sequence ID" value="ABX05653"/>
        <property type="gene ID" value="Haur_3015"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3015"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011786_1_0_0"/>
    <dbReference type="OMA" id="RHGNMGE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3047-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04842">
        <property type="entry name" value="Peptidases_S8_Kp43_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034058">
        <property type="entry name" value="TagA/B/C/D_pept_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735449" evidence="5">
        <location>
            <begin position="23"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="255"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="716"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="721"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="835" mass="88136" checksum="2D9BA457EFE607C9" modified="2008-01-15" version="1">MRLFHGLLLMSLVLLSFGGAASKPPSTTIPPKLYLQRGTIDLKVVNQANQADPLLQTVGGYAVIQFSGPVLLKQRQALEATGLSIIEYLPDYAYLVRGSAAQQAAASRIDGFYARGDWTLADKFHPGLLKLMRTGAYQGLALQTIGWDNQLTTAEQAVKAQGLKLDAISTIDQLIQLAQINEVRWIEVASTPKLFDQYARQVQQVEPVWTDRQLYGQNQIVAYTDTGLDTGSLTTLNNDFTNRILATQVLSAGGHWDDNHGHGTHVAGSIAGNGALSGSNPATHTYTNSMAGIAPEAKLVVQAFEATATGDIIGLPTDLYPMYQQAYDAGARIHSNSWGDATGPVSDTEAAFGGYPYNAQRTDQFLWEHPDYTMLFGAGNSGVDGTPSQAIFCTGGNGVVDPDSLLAPGTAKNVITVGASESPRPTGGYTGVPWLLLSFCFATAPINTDTLSDDANGIAAFSSRGPTDDGRIKPDLVAPGTNILSTRSYGSGAGALWGVHETNANYLYSGGTSMSTPLVAGTVALIRQWLGIQGLPNPSAAVIKSIVLNTTVDIAPGQYGTGATQEIPYNRPNSVAGWGRSNLSFITKPAPYHLWVADQTTGLNTGQMVSYNHTASQPLTVLTNTQPLRVMLNWTDPPASLAATQQLVNDLDLVLIGPDGTRYYGNNQSTGDRTNNTEGVIINNPQIGAYQIEVTAHNVPISSQAYGLSVAGPLREATGGGTPTPTPTAIATATNTPTNTATNTPTNTATNTPTNTPTNTPTNTPTNTPTNTPTNTATNTPTNTATNTPTNTPTNTPTNTATNTPTNSPTPTNLPTVTTTAVTNEYDVWIPWASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X0</accession>
    <name>A9B4X0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3055"/>
    <dbReference type="EnsemblBacteria" id="ABX05693">
        <property type="protein sequence ID" value="ABX05693"/>
        <property type="gene ID" value="Haur_3055"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3055"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_443967_0_0_0"/>
    <dbReference type="OMA" id="GHPPYGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3087-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045543">
        <property type="entry name" value="TCAD7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19973">
        <property type="entry name" value="TCAD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCAD7" evidence="2">
        <location>
            <begin position="7"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="342"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="615" mass="67656" checksum="74C975F066C2E13D" modified="2008-01-15" version="1">MSSRSINRRLLVLQAGWTVAQAQLLLAHSQAEYVVVQRTEPQIYWYVYPLEVVQERLSYHHPDIAIYLALNLQETSASSTLNSNQLETADYLSVVLDDQQHLQGVVNPSAQAKGTEFDPFFKAYPSVVAQNQAQLNQAFDLAVGFRDTPDAGLIGGHNPIVIHGLQTDERCTIMLSGDGLQFDREQAELAFDIQATVFFKATPTRTGRCVIYVDYYRQRQLVGHAERVVLVDSNAEPEPSNASPFDFGSTPVDLLINLRRDGDTFKWTAMPHDQAFTPVHNLPSQQALSEQAAQNCAVDLLGAAVNPSLLLAQRELEALASDLGQFVPSPIWQLHSDLAQKLQRPLTVLLRSNDLALPWELAMVEAPLLAGDQPLYWAAQTHFARWYIHPQVSPMPPDQLNISQISAIASRYGWDSGQAELVHAVDEQTMLQNQWQAQAYEATIQALDPLLSQATTQAGHLLHFAVHGRSQPNARIQEIILADNNAISAKALVGNTRRRPPQFSFVFINACQVATPGQSLGQAAGFPAEILKSGAAGFVAPLWEADDQAAGTFAAQFYSQAFQAQPLGAILQQYRLSYVANSTTTRLAYIFYGHPALRLAYSSKGATHAQQPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B500</accession>
    <name>A9B500_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3085"/>
    <dbReference type="EnsemblBacteria" id="ABX05723">
        <property type="protein sequence ID" value="ABX05723"/>
        <property type="gene ID" value="Haur_3085"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3085"/>
    <dbReference type="HOGENOM" id="CLU_211022_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3117-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="48" mass="5479" checksum="F79E96CFB2C90855" modified="2008-01-15" version="1">MTYTLIGAAMEVHQQLGPGLLESVYQKALAYELQQRHVLFVEQQHLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B511</accession>
    <name>A9B511_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division protein FtsW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3512</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3512"/>
    <dbReference type="EnsemblBacteria" id="ABX06148">
        <property type="protein sequence ID" value="ABX06148"/>
        <property type="gene ID" value="Haur_3512"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3512"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_1_1_0"/>
    <dbReference type="OMA" id="KLWWSNL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3549-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="480" mass="52584" checksum="51BCBA1D394494B5" modified="2008-01-15" version="1">MNDRVPRKPDGMLLALVGGLVAFGLVMVYSSSFYVAYAEYGSSVYWVLRQTMWAIAGVGAMIATMRFDYRKLRRFSLPLMLITLFLLLLVLLLPEHITKVNGASRWINIGPVGMQPSEIAKFAAIIYFADWLSRRGSKIRQFVTGLLPFGIMLGLLAGLVLLQPNMSTTIVIVVISAAILFTSGASLTHLGIAASMTTVVGWLAIQSAGYRALRVLVWQDPFSYPRDGGYQPIHALYALGSGSWTGVGLGQSRQKFFWLPFAHTDAIYAVIGEELGIIGAGLVLAAFVVLAVRGFRIASRTLDPFGALIAVGVTTWLVVQALINIAVVTTVIPFTGITLPFISYGGSSLMMTMIAAGLLLSVTRYAPLKRAEERTNELSIPTIGQLRPRVVAAADAVRRWHGRPRVSGFGGGQRPEENHRSGSFAVGNSLGGTWRKPADESKRLIAWRKPKQRKNLVSQPINGSTARERIEQRRRNKRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B584</accession>
    <name>A9B584_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3585"/>
    <dbReference type="EnsemblBacteria" id="ABX06221">
        <property type="protein sequence ID" value="ABX06221"/>
        <property type="gene ID" value="Haur_3585"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3585"/>
    <dbReference type="eggNOG" id="ENOG5030IRW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_363218_0_0_0"/>
    <dbReference type="OMA" id="WPESALH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3624-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018513">
        <property type="entry name" value="Cell_synthase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39083">
        <property type="entry name" value="PTHR39083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03170">
        <property type="entry name" value="BcsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735276" evidence="2">
        <location>
            <begin position="28"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="737"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="769" mass="82309" checksum="8C3B6A3108F18548" modified="2008-01-15" version="1">MVRLVRVFLLFSVALGLFASLPMVSQAARTSLNPISATTAAAPLNQATVTPVVTDSDTVTFAQLGAREDSMEGPFNARYINIRLPNTWKLEPGAAITLDFETFVSGSAVSSEENVQFFAGSMDVQFNNVQLERIFLDRSGPRQVTIPISATAYTSTRIDGAHTLGILLDAGLNCGNDSQTSVIIRATSSLKLPHTLGTLSTDVKQLPRPIFQDSPLEPDVATIIVPNNASAAELEAGLIVAAKVGSITSSRIQVPLIAESVLSPTLRTESHLIFVGQAANFENLDAVDFAEGSGAEGFNLSEAQAADGIIQMATSPWNQQRVVLALSGNDDEGVIKAAKAFSTGNIRASSEPSIAVVAEVNSPDVLTKTLNLQITDVPSTGLTVERSFRSLGFETVSEFGIGGHTFELNVDMPSGYEMNDDGYIEVHFAHSALLDYSVSAMMVRVNDRPAGSIRFDDTTAQNGVGRVPIARGNLNVGRNRITISANLIPNTPCVDPNLAGIWYTLRADSMIGIPVRATRGRSVVLRNLATFLEPLTISNTLKNLAFVVPSDDPASWTVAGQLATALGDSLDPAFVELRAVNPEQVASVQANHDLILVGQAPDHAILQDPALQPIIPAPFAQGSKHPTLGNSRVVYRIPAELSLGYLEFMRSPWNEQRSILAVLGSTDQGVQWSGNALTTSRLRTRLNGSLAIVNDQQISVEDPTVTGDTAGIANDALGENQDDPIYREVIPPTKPEWILYAIAGLLVVMVIISVIVIIQAARKRKQRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5L4</accession>
    <name>A9B5L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1604"/>
    <dbReference type="EnsemblBacteria" id="ABX04247">
        <property type="protein sequence ID" value="ABX04247"/>
        <property type="gene ID" value="Haur_1604"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1604"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_0_0"/>
    <dbReference type="OMA" id="MGSNMIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1628-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="54"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="349"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="46188" checksum="93220D5BE18C6818" modified="2008-01-15" version="1">MMTTLDVQTVPTPAPAASDDILFQPIEASSSGFGSLWEVVRISFGSLLANKVRSLLTMLGVIIGVASVVSLLALGNGASASITGEIEAIGTNVLTISAGSQNRGPGNATAAQNLTMDDARAIEALQLPVIGVAPQLNSNAQIVAKSADKSAQIVGITPSFQVVNNLAMQQGSFITEEHLQGANTVIVLGSTLAKDLFGNGQAVGQTVRINNQSLRVVGVLTPQGGSAFGSEDDRAYIPITTAQKRLFNARTPDGNGYRVGSITLSAINASDLDALQSRVSMLLRERHHLKLDGSADDFNVINQAEILGTLTTITSMMTLFLAAVAGISLLVGGIGIMNIMLVSVTERTREIGLRKAVGARSHHILMQFVVEAAVLSMTGGMIGLMLGSIIPIVVTQMGLLDAPIDLQTVGVAIGFSLGVGLFFGIYPAQRAAKLNPIDALRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M0</accession>
    <name>A9B5M0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase with GAF sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1610"/>
    <dbReference type="EnsemblBacteria" id="ABX04253">
        <property type="protein sequence ID" value="ABX04253"/>
        <property type="gene ID" value="Haur_1610"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1610"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_515598_0_0_0"/>
    <dbReference type="OMA" id="YFPVMAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1634-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="344"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="528" mass="57978" checksum="4EE377718E69E4D4" modified="2008-01-15" version="1">MPEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLEDCPAQNITIERWRPQDAASLMLALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVLGSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNRELETIYRLDRLIDATPDFDQGLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVDQGKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDTALFEDRQQRHIRETFARYVSPDVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQLPADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFGAPLPYEQHPLLAVQTGLLMQARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAALPNQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5N4</accession>
    <name>A9B5N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1624"/>
    <dbReference type="EnsemblBacteria" id="ABX04267">
        <property type="protein sequence ID" value="ABX04267"/>
        <property type="gene ID" value="Haur_1624"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1624"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_11_1_0"/>
    <dbReference type="OMA" id="WGIWLIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1648-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="22"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17036" checksum="2A56E854B396D8E3" modified="2008-01-15" version="1">MSNPQHMAPSGDEERVIELHLPSRLGYEKVAMDTASAMAKRMGFSHDRVESLRTAVSEAVTNAIEHGNQHDSAMKVVVVFTGSDDGLIVDVADQGRKLLDHTITERTPDIHQVLHSDDKGGWGIWLIKELMDEVQFSVAPSGGNKLRMVIHLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R0</accession>
    <name>A9B5R0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1650"/>
    <dbReference type="EnsemblBacteria" id="ABX04293">
        <property type="protein sequence ID" value="ABX04293"/>
        <property type="gene ID" value="Haur_1650"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1650"/>
    <dbReference type="HOGENOM" id="CLU_1426212_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1674-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731903" evidence="3">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="19399" checksum="25C133018CACB3C7" modified="2008-01-15" version="1">MTRFIRSLVILLIALVALPTQPSHAADVGPLALTPTEPPTPTNTPLPTNTPEPIIPTNTPLPTNTPEPRVTVEPTSIAQPTGVAPTQAPSIEPTATPIISMPGITATATPEQSIPSPTPSPSPTPEQPSATPMPSATAMPQPTAKPAAPPAGNQPPLPRTSSADTAALWFIGLLGLLVALIGFGIQRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B642</accession>
    <name>A9B642_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase-like_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3617"/>
    <dbReference type="EnsemblBacteria" id="ABX06253">
        <property type="protein sequence ID" value="ABX06253"/>
        <property type="gene ID" value="Haur_3617"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3617"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083550_0_0_0"/>
    <dbReference type="OMA" id="PSLIQWD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3656-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="215" mass="23599" checksum="EAA39D76D6B4FBCB" modified="2008-01-15" version="1">MMPLATWIDHLVVTAPDLALGVAYIEDLLGVPMQAGGQHQAMATHNCLLKLGEHCYLEVIAPDPTLAAPDRPRWFALDSLQPTSAPRLATWVAQTILIQAASELLHQQLGVVTPMRRGDLAWQITIPADGSLPFAGVAPMLIEWPREQHPIQRLTDQGCRLLQLELHHPQASQIEIMLSQIGMKDVIRWQTAAQPQLIATIATPSGIRHIEQAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B649</accession>
    <name>A9B649_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3624"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06260">
        <property type="protein sequence ID" value="ABX06260"/>
        <property type="gene ID" value="Haur_3624"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3624"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_0"/>
    <dbReference type="OMA" id="FDIPITH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3663-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="245" mass="27464" checksum="79460C8E107A8604" modified="2008-01-15" version="1">MDSQPDLSIVFPAYNEAENIEASILDAIQVLNQLGLNGEIVVVNDGSHDQTANVVRDVATRHHQVHLINHDMNQGYGAAVWTGLTNAMGKLVFFCDADRQFDLAELEKLVARRHHAPLVVGYRAPRRDPVLRRLNGWGWSHLVTLLFGYTARDIDCAFKMLDQRVIDTLRQQVQSRGATFSAELLVRAKRAGFQIAEVAIIGHRPRVAGKPTGAKLSVILRAFRELLQLYRVLNRESRTTKPAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B696</accession>
    <name>A9B696_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3671"/>
    <dbReference type="EnsemblBacteria" id="ABX06307">
        <property type="protein sequence ID" value="ABX06307"/>
        <property type="gene ID" value="Haur_3671"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3671"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_8_4_0"/>
    <dbReference type="OMA" id="RILEAWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3710-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="23272" checksum="10880C4B46D7F072" modified="2008-01-15" version="1">MPDPRGLRLLLARHGATAWNEAGRYQGRADEGLSQRGQAQATQLGQWLSDETPEIVLHSGARRTAETLARALPQHQAISDPRWREIDHGEWEGLTYRQVLDQAPEQARAHWNDPLHIPAPQGETLITVAERVQAATNDLITNYAGRSVLLVAHATSLQVLCCQLFQTPLKLYWQWKFDLGSLSCLELYQSGTIINWLNRGYTRPASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I2</accession>
    <name>A9B6I2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0233"/>
    <dbReference type="EnsemblBacteria" id="ABX02885">
        <property type="protein sequence ID" value="ABX02885"/>
        <property type="gene ID" value="Haur_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0233"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145964_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="130"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="191"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="26414" checksum="60E6DC27924AB265" modified="2008-01-15" version="1">MADKEKKGLFGNLADQMKDAIEQSRESAEAKPTAPAPGNVIGQMMERLHDIQEKQEEAASSSVSNAVNVIKDAQEAAKEAREKAEAQSAATNNAVADALRQAQEAAKAQEVAKAEAAKAEAAKAEAAAEQRYTVQGGDTLGKISARFYGDAAQWRRIYEANRAIIGNNPDVISVGQEFVIPDASTPLPVQRTYTVRSGDTMRAIAQRFYGDEMQWKRIYQANRDRIPNPDVIHVGQEFIIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q7</accession>
    <name>A9B6Q7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04366">
        <property type="protein sequence ID" value="ABX04366"/>
        <property type="gene ID" value="Haur_1723"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1723"/>
    <dbReference type="HOGENOM" id="CLU_1893322_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1750-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N_BRCA1_IG" evidence="1">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14659" checksum="5810911E9C16C32D" modified="2008-01-15" version="1">MRIIKRGILLGLLGLMTMVGSVVTRPSTPADAAKLCLQFLYDVNYPDGTVVGKNRQLRKEWQVFNCGTRTWGTSFTFRRVSHLFPVGAFATGAFNLTSPIAGNQQGTIYVDLTTGSESGNFKASYQLYTPGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X9</accession>
    <name>A9B6X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3210"/>
    <dbReference type="EnsemblBacteria" id="ABX05847">
        <property type="protein sequence ID" value="ABX05847"/>
        <property type="gene ID" value="Haur_3210"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3210"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_2_0_0"/>
    <dbReference type="OMA" id="ELSNICC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3245-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_MERR_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="15397" checksum="602E3B73613EA314" modified="2008-01-15" version="1">MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSLREMGMFLQLSPQNTEQALIQQFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPVIYALAEMACAQGVSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B713</accession>
    <name>A9B713_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3244"/>
    <dbReference type="EnsemblBacteria" id="ABX05881">
        <property type="protein sequence ID" value="ABX05881"/>
        <property type="gene ID" value="Haur_3244"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3244"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_3_1_0"/>
    <dbReference type="OMA" id="MDEMAFL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3279-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="18641" checksum="5DF7E610B3CB4699" modified="2008-01-15" version="1">MNERPIRRTPLIRMSDIVLPGQTNNHGTMFGGEVLAMMDRAAAIAAIRFCRQQVVTASTERIDFRTPIHHGDLVDMLAKVIYTGTTSLIVRIDAWAEDPISGERRWCTTGFYSMVSVGIDGRPTAIPRLLVETPTEQADWEHGAKIKALISERLKANDAPIPADPLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N1</accession>
    <name>A9B7N1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0353"/>
    <dbReference type="EnsemblBacteria" id="ABX03004">
        <property type="protein sequence ID" value="ABX03004"/>
        <property type="gene ID" value="Haur_0353"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0353"/>
    <dbReference type="eggNOG" id="COG2314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1487122_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-356-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="96"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20086" checksum="97A5F8E48F5EE5EB" modified="2008-01-15" version="1">MTQPFYKICPTCNTQTHPDVMFCTNCGGSLQGSPVHGAQTVAYQQNSTPAQPGYQQYSQPVQPPPMYQANYQQPIAPYQQPNQYQYQVPQGYAYTEKNKVVAALLAFFLGPLGIHGFYLGNSQMGLILLLSNVVFLPLSCFGIGLLGYALTGIICLVQTVLYLVASDAEFYQKYVVQKSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R5</accession>
    <name>A9B7R5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1800"/>
    <dbReference type="EnsemblBacteria" id="ABX04443">
        <property type="protein sequence ID" value="ABX04443"/>
        <property type="gene ID" value="Haur_1800"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1800"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_0"/>
    <dbReference type="OMA" id="AKDANTM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1828-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008667">
        <property type="term" value="F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003560">
        <property type="entry name" value="DHB_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01397">
        <property type="entry name" value="DHBDHDRGNASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04316">
        <property type="entry name" value="dhbA_paeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="27907" checksum="D1C9DD506194F816" modified="2008-01-15" version="1">MQFSEYPELKNQVALVTGAAQGIGAAVAQELCRHGAHVMALDVQSAGLQALQQRLETSAGQLSTHTIDVRKAQAVETLVDAIEKQTGPIGLLVNVAGILRMAPVVELSDEDWATSLDVNATGVFNLTRAVARRMVPRQAGSIVTVGSNAAGVPRMQMAAYAASKAAATAFTMCLGLELAQHKIRCNVVSPGSTDTAMQRMLWHDETGPQRVIAGALEIFRLGIPLGRIAEPADIANAVVFLLSERARHITMHDLRIDGGATLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R8</accession>
    <name>A9B7R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,3-dihydroxybenzoate-AMP ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1803"/>
    <dbReference type="EnsemblBacteria" id="ABX04446">
        <property type="protein sequence ID" value="ABX04446"/>
        <property type="gene ID" value="Haur_1803"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1803"/>
    <dbReference type="eggNOG" id="COG1021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_0"/>
    <dbReference type="OMA" id="PMSPHDE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1831-MON"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008668">
        <property type="term" value="F:(2,3-dihydroxybenzoyl)adenylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011963">
        <property type="entry name" value="DHB_AMP_lig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02275">
        <property type="entry name" value="DHB_AMP_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="3">
        <location>
            <begin position="38"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="4">
        <location>
            <begin position="450"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="542" mass="59097" checksum="36E8D01A140695CF" modified="2008-01-15" version="1">MAELTLGLEGTTAWPAEFAERYRKAGYWVDQTFGEALREWAQRSGDATAVVCGERRWSYRELDQRVDRLAAGLQQLGIQTKQRVVVQLPNCAEWFVVCFALFRVGAIPLMALPAHRLAEIGYFCQHSEAVAYVIADKVGSFDYRNLAAEVKAVAPTLEHVLVVGEAGPFTALAEVDAEPSEFPTLDPAEVALFQLSGGSTGVPKLIARTHDDYLYSVRASAEICKLDASSVYLCVLPMAHNFPMSSPGTLGTLAAGGTVVLAPQPSPDVAFPLIAREGVTITGMVPPLALLWLDAAANRKAELSSLKQILVGGAPFGAYTARRVQPELGCQLQQVYGMAEGLVNYTRLDDAAELICHTQGRPISPLDEVRIVDDEDNDVPLGELGHLITRGPYTIRGYYRAAEHNQRAFTSDGFYRTGDLARLNATGYVSVEGRAKDQINRGGEKVAAEEIEQHLLNHPAIHDVALVGLPDRFLGERTCAVIVSNGVNINRREVLQFLRSRGLAEYKLPDRVEIVESLPKTGVGKINKRLLREQLSAGRVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T3</accession>
    <name>A9B7T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1818"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM63">
        <property type="family name" value="Carbohydrate-Binding Module Family 63"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04461">
        <property type="protein sequence ID" value="ABX04461"/>
        <property type="gene ID" value="Haur_1818"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1818"/>
    <dbReference type="eggNOG" id="COG4305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572092_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1846-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="SSF49590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="250"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="477" mass="51246" checksum="444402DFAFA41214" modified="2008-01-15" version="1">MAWRKGTFFSFGLILSLLLTSALFVAQGSAQRMQTIADPWALRSGRATFYDPTVGMGNCSLPVPSDMLLAAMNTTDYGLADYCGAYVTVNGPRGSVTVKIIDRCPGCVVGGIDLSPQAFERIAALEAGNVPITWQLISAPNVSGNVIYNYKEGSSQWWAGVQVRNHRNAIAKFEYRNPQGIFQNVDRVQYNYFLVPGGMGTGPFTFRLTDVYGNVFTDNTIPLRSEGDVAGNQQFPFVPTPGSTPTASPTRTASPTVVSPTTRPDQTIMNASSTEAGGSTHYALDGNLNTRWSSGLPQAAGQWIYIGLPRVTPISGIKLDAGSSGGDYPAGFIVQTRDDTSDWATVATGSGSSQITTINFAARNARYVRIELTARSANWWSIHELTVIFAAQPATLTPTILPPTNTIVPATVTPTLVPTMAPPPLTATPTLSAWQAYTNYSVGSLVQHNGINYRCIQAHTSLPGWEPQIVPALWQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U1</accession>
    <name>A9B7U1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1826"/>
    <dbReference type="EnsemblBacteria" id="ABX04469">
        <property type="protein sequence ID" value="ABX04469"/>
        <property type="gene ID" value="Haur_1826"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1826"/>
    <dbReference type="HOGENOM" id="CLU_3008107_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1854-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025844">
        <property type="entry name" value="Herpeto_peptide"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14409">
        <property type="entry name" value="Herpeto_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="57" mass="6203" checksum="E5AB51523BCBB5EA" modified="2008-01-15" version="1">MEFNTIKTEELPIIFGLTYLEEEAAEINDVVGCLMPIDGEGYTVTGCDDSDGGYLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z4</accession>
    <name>A9B7Z4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YtkA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3290"/>
    <dbReference type="EnsemblBacteria" id="ABX05927">
        <property type="protein sequence ID" value="ABX05927"/>
        <property type="gene ID" value="Haur_3290"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3290"/>
    <dbReference type="HOGENOM" id="CLU_163276_0_0_0"/>
    <dbReference type="OMA" id="MTHAGMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3327-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032693">
        <property type="entry name" value="YtkA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13115">
        <property type="entry name" value="YtkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YtkA" evidence="1">
        <location>
            <begin position="29"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13442" checksum="ECF3853BC8BB7A3C" modified="2008-01-15" version="1">MLRYTQLILLSLILVSLLGCSRTPSDDPRLNISLEQTPSTMAVQTIVLSISDGATPLENAKVQIEATMTHAGMPSQIVQLEPLGAGKYQANIDFSMLGEWVLIVNVTESNGAVMQRTLPAFNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B801</accession>
    <name>A9B801_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3298"/>
    <dbReference type="EnsemblBacteria" id="ABX05934">
        <property type="protein sequence ID" value="ABX05934"/>
        <property type="gene ID" value="Haur_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3298"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1658412_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3335-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="17284" checksum="F2CAD6BFBA59B817" modified="2008-01-15" version="1">MSDDNTSSVGHRRWLLYPPTLKMGTGDVKAQTGTLDANSLWVVGNTGPRPATRTEYIAWPPAGFVPFMNAYKRWSFSLPNANFANAVVTMQKSGQSQALTIVSRSSGSGDNTIAWDVTGYSSWPAPATDITYTVNVSNVVQNGQTRSFSYQVTVIDPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B888</accession>
    <name>A9B888_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3805"/>
    <dbReference type="EnsemblBacteria" id="ABX06441">
        <property type="protein sequence ID" value="ABX06441"/>
        <property type="gene ID" value="Haur_3805"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3805"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_5_0"/>
    <dbReference type="OMA" id="YSAVTQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3847-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731998" evidence="2">
        <location>
            <begin position="20"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="76"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="450" mass="48118" checksum="CD5FAFA47997E46B" modified="2008-01-15" version="1">MKRLISMLVILVTAIQLLAACSSGTGVEPTAATNPTSDSAQATEAPPATTAPAATTESTEPTAAPTSDSAAATGKPIKIGLITDQSKALSLYGTQEINGFMLGLEYATNGTMQVAGRPIEVIVKDDENNPERARQLARELIEKDGVELLQCCASTSSALTVIEIAKENNIIAMIDPAAGPQITGSNFNRFVFRTGRNTLQDALTAGPYMVENVGKEFVQLAPDTDFGKGSAASWRSIIEANGGTFVSDDVFIPADTTDFTPYLQKLLDAADEKQAKVLMVTWAGANFPRLFQQMQEQGVLDKLTLATGFGDNVTMPMVYADAVGSVGMIAYHYTLPKNEVNDWLVEQHKAKYGSYPDLFTAGGMASGIATVRGLEATKGDTNADALIAALEGMSFEGPKGIYTFRKEDHQALQPMYMVKLISITDPDAKFFELLQERSAEQTAPPVMVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D6</accession>
    <name>A9B8D6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3855"/>
    <dbReference type="EnsemblBacteria" id="ABX06489">
        <property type="protein sequence ID" value="ABX06489"/>
        <property type="gene ID" value="Haur_3855"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3855"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068889_0_0_0"/>
    <dbReference type="OMA" id="HEINYFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3897-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
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    <dbReference type="InterPro" id="IPR011009">
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    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="28"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="38462" checksum="27DB0A005359A491" modified="2008-01-15" version="1">MQQALAPDPATIRQHLTQTYAIQPNRIEQINRGNDPRAAIYHVQTNEQPYFLKLKAGSIYQAGVLLSRYLKDRGVAAVAPVDTRTQQLWSHCQQFHSVLYPYIEGATGMDQGMSALQWRSFGQQLRRIHTMQVRAPLRQMLQWEQFRPLWLPTVQAIHNSINTWPIGDSYSAELIDFWRVKSVEISYLIKRISALGHELRANAGDFGLSHGDIHTANIVLDQIQQINIVDWDYPMFAPKERDLRFVVGSVIGVPVQQHEEQWFFEGYGQPTIDYKALAYYRYERVIQDLGDYAQRVLLRRDAPPAFKQAALQSLRSRFSTGNIIESAYQADRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8F6</accession>
    <name>A9B8F6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3875"/>
    <dbReference type="EnsemblBacteria" id="ABX06509">
        <property type="protein sequence ID" value="ABX06509"/>
        <property type="gene ID" value="Haur_3875"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3875"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1882895_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3917-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14981" checksum="0FA355AED4C409B0" modified="2008-01-15" version="1">MMRILAPAEALALLDELSVLRIAGFDQARSASYAVPLAFVRRDQCLLIAIRATGRLAQLLQQQPQGWCIEADQINPDWTFRSVVAQASAQPLADPHIALVALAERYGRNWPQWRPNAPIQAFSLELAAIQGRHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8V9</accession>
    <name>A9B8V9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07773">
        <property type="protein sequence ID" value="ABX07773"/>
        <property type="gene ID" value="Haur_5145"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5145"/>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5207-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="66"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1689" mass="188697" checksum="0F341881CEDEADF5" modified="2008-01-15" version="1">MSSAFASFHLTIAAPHGDRYPVTARTQAGHEVSEDLLLPLDDPTLTVYQMALDYHTPIDESVVIAVGQLLYQTLFQGTIAEAFATARAHADQQKVALRIHLAIDTDTRLSAAAALPWELMATAAGRPLMLEHALVRTFSWNDPIPNLGIPPGEPIRLAVTSALPAELANHPIAAEAEVAIIHAAITHSARPIDLIEVPHLTRDRLTDLLTNQRPHIVHHIGHGSIQRGMGYLDIERADQSRDRLSAREFSTMLHQSGVQLVVLNACHTSSAGESLLTSFAPIFITDRIPAVIGMQAAILNRTGHCFANAFYATLGHSGSIDASLIAARKAIHADGHEHGAWGFITLYSRVTHGGLWQTQHADHTNSTSPPTVIQNTIEPIQAHGSNILIGNQIQGNVYQHVDLPEATLKASLAALEQEKTLARIRHAAQQIESDRLLTLRLQGFVGRVNELAAIREQIAAMRPTGGYVLIKAAAGEGKSSSIAKLIQEAGIAQTPHHFIALTTGREYQLGLLRAVVAQLILKHGLTVSYFPEESYPAMKGEFTRILDELSKQGIQETIYLDGLDQLQPDIDGSRDLSFLPPQPPPGIVMVLGSRPDETLKPLEILHRVDYDLPPLREDDALALWRSVQPGVSDSLLHNLYTALKGNALFVHLAADTMQGASVVDATSLIKQIEQNPSNLFGITLERIKGRSMSDWRSIWKPMLALLLVAQEPLRLDVLGDLLGHDHDTMQDAVWVFGGLVSQGIDQRVALHHLLFRDYLTTSVFNDREVKRWHQRLADWCDSDLDAIWADDRDPIEQARRVYARHHYIMHLFLAENWTTLWKVLDTGDYGEYKTRFDPSTRLYALDLDRGRESAINAGQSTKENIQNLPRLWKYSLLRTSLNNRMDQSSDELFVILAMLGRLEESLARIELISDPIRQIGLWSIVVQWCDPHQQKILLYRMESLLPMIPVQSKQEALQSIIQVCIWIGDLDQAYNLAQTIDDNEQRASILCDIAQAHPESYPTDQLDNLLNEAFLLVEFINDPNSASPLYHRIVTLLTNRSMIVQAAALADKIDNPWQRARTLYDIVWLLVQKHECIPALTIAYMIEDSSYLLHAMITITLAFAEAGDSEQVERLLYKILQDTATIRHIEQSIQVYSAIAEIYTKVGNAKQANSYFHAIETLIHSIDAPEKQVDELCFMAKTYNRMKMDMLRDTYLDNAIALAHTIDEPSAQGNAFKAISKAYTVLGDLSRAITISTLIADYDIRETTLGQVIQIVLNNPSNGNSQAVLNEVRNIAQSINHSWWRIKSTYSLIYTYVNNGNLDQAHKLLGSEFQTLSYAVDEDSLSTLEKTRVCVLCSIAAASFAIQNLGVSYTLMDEAITITKRILEPRTHIHAVETIAQTYAVMNDHNQATIFLQHALEMAKSIDDGDLQFELIDSIATISIRIGNIEQAMTILESVNTYDRFGSSSILPGIAIEFADRGQIEQAIEFSQSVKSREKDFVYRAIAQAYCTAGDQERAKHITQSIKTMWKYIDTLSIIARSYVSVDKIEQAKDLIAEMKTRITILPNDNDRDYAYGSLSQALATIGQITQAIETIQLINTTGSRDEAIYTLAQVYAAQGNITHALAEAKSITHIRRRIALFLSLGNEYRDDDSLKISLIQKEWQASRTIEDTWELLQLINPLLNDYPWLGTVILEEEKWVNAQLKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B942</accession>
    <name>A9B942_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07856">
        <property type="protein sequence ID" value="ABX07856"/>
        <property type="gene ID" value="Haur_5229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5229"/>
    <dbReference type="HOGENOM" id="CLU_1439274_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5291-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20860" checksum="4B132F293D828022" modified="2008-01-15" version="1">MTTHEIQNPDYDIWSHVTLSRYAYVISALPIGKIKIAIGGYGKKVIPMLSAYIPVPKVRLLIHRILDSVNPPSNGFSFEVIGGSSRDGVVESRILKFVFDAGQNGQFASMPWRIVIGIGPGKLLETGGISPIGKPTSVADIRLSTDDMTMLALELEAHLRHRQGTYEYHRIREQRERHAQRTADPDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY1</accession>
    <name>A9AUY1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DinB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3935"/>
    <dbReference type="EnsemblBacteria" id="ABX06569">
        <property type="protein sequence ID" value="ABX06569"/>
        <property type="gene ID" value="Haur_3935"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3935"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101283_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3977-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="PTHR37302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="18125" checksum="9C6BAA17E310BD7A" modified="2008-01-15" version="1">MQALTIIKSLFAYNADFDQRIWGSIEGLSDEQFCADYPYSQGSLRNHLVHIASVERAWLTGLQTGERPKHLDPLEYPTIASVRDVFNQMRGQVTSYIEQLSDEQLDDVLPGMNLARWQVLVQIANHATDHRAQILRILHDYGQKTFDQDIVLHFWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY6</accession>
    <name>A9AUY6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3940"/>
    <dbReference type="EnsemblBacteria" id="ABX06574">
        <property type="protein sequence ID" value="ABX06574"/>
        <property type="gene ID" value="Haur_3940"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3940"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040530_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3982-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="514" mass="56615" checksum="075BE3476D80DBBC" modified="2008-01-15" version="1">MPMPPLWHLSLNRSSVATTKLHSQMPSFASTAYLRRFLLRHIARFLALGCLLAVSMTPIRAQANPTLWAAAASTDTLVLASGQLTLAPNAAQAAAVYGSYARFGMFDSAPQNIAPANQVLVTWGATVPAAASVRVDVRGFNGQRWSDWTLDVQSGQTVAFATIARQIQYRLVLLANEAAPVVDFVQLAPNTLAESDAISIMEDEPIAPTYHIRATRMGLVGDRTANGHIIQPNDWFVSLPSFRSLSSRGGGEYMARLSYRGKSIVVPVWEVGPWNIHDDYWNVEREKFGDLPVGWPQDHAAYFDGYNGGWAEKGRVRFPTAADVGDGAWVALGIPFNDEQEELDITFLWLGRDPGDNPDPMPVGSVTPEPAPIEELPAGTIQVDNQGEQFSRSDVAWFEFSCGKNRHSFWTFSTNKPEEAVNNARWTTPLEAGDYSVTVFVPYCPNGKSDTTSARYVVQHADGETQVVVNQAEHAGNWVELGRYRFDGTGTVSLSDLADDRMKAIWFDSVRWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV57</accession>
    <name>A9AV57_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0484"/>
    <dbReference type="EnsemblBacteria" id="ABX03135">
        <property type="protein sequence ID" value="ABX03135"/>
        <property type="gene ID" value="Haur_0484"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0484"/>
    <dbReference type="eggNOG" id="COG4248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688450_0_0_0"/>
    <dbReference type="OMA" id="QIATRSK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-490-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="45241" checksum="8186C49D68EB303C" modified="2008-01-15" version="1">MMTFSYRTKQHIHVQLDQLNPLGKGGEGSVYSVINTPNYPNHCAKIFHPNRLTADLERKINFMVDNQPSTLISTNYRIAWPIASLYHNKKFYGFIMPKAFDKSIGLERVTQPQISLKGIDTQWIKYQRNDKQGMINCFKVCVNIAFIVNLIHQMKKYTFVDLKPQNILVNLNGFVSITDIDSMQVYDPQKNLYYKSVVSTAEYSPPEYQSYLKKGGNITQEWDNFSMAVIFYQLMTGVHPFAATFGGKFSNSTTIDDHISQSLFVFGDNRQTITKLPPLHTYYQQIPLNIQQLFLRAFDKPVSQRPTAEEWGQNLFELVSKDSHLIASNTAVAALALPVKSALKPAAQSTTGHVQMFQLTKASTHSQGSQSTKAPHKSYAWVGWLIVLVCIIVVIAVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV62</accession>
    <name>A9AV62_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysyl endopeptidase</fullName>
            <ecNumber evidence="2">3.4.21.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.50" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0489"/>
    <dbReference type="EnsemblBacteria" id="ABX03140">
        <property type="protein sequence ID" value="ABX03140"/>
        <property type="gene ID" value="Haur_0489"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0489"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_330317_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-495-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="568"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="868" mass="91614" checksum="0BAE079693C2E007" modified="2008-01-15" version="1">MVRSRWVFALLAITVLLSVIGAKVPFTAAQNQASTSDRPLALAQGLKDLNTVAQIAVPELDLAKERADAAKRPSNLPTRFAKDYQTTLDIKQVASIEIVGNRTVARLRIDAPKALSINVGFTSYNLPKSGQLFLYSPDYRSILGPYSAADNEEHGQLWTPIVAGDQMVIEYSADSGEFALADLTLSAINRGFSGFGIPRDLLVDKSGSCNVDVVCPEGDDWRAEINSVAAYTRNGLDMCSGALINTTANDQKPYFLTANHCGITAENAATVVTYWNYESTLCRTVGSAENGTPLPKPNTTMTGATLLANYAASDFALIELDDEVPTEYAPFWSGWNAQSGDFPSVVAIHHPGVEEKRISFENQATQTTDYLGTTVPGGGTHIRVIDWDLGTTEGGSSGSPLYDPNHRIVGQLHGGYAACGNDRDDWYGRISVSWNGGGSSTSRLKDWLDPTNSGSLVLDGTGGTPAFTMNVNPASVAVCAPVSAQTTVNLGWVQGFSEPVTLSASNLPAGATASFTPNPVISPTLSSQLTIGNLSTAMAGDYSVVIRGDSTTISRTTDLDLSISGGLPSAAPSLTAPANNATNVSETPAFSWSSAAGATNYVLEVASDASFSNLVYTATTELTSLTSAPLSTNTKHYWRVRAANACGVSANSSIFSFTTEAAPGDCPIGTETVVAFNETFDSDPSWTHGGTGDTWAHGAFGYNGGNGIKAIDPDSTSDQWITTPAISLTEGLTPTLQFWNSQTIEDRNAGGCYDGALVEVSTDGGSAWNQIPNSALLTDPYNGAINASTNPLNGSQAWCGDPQDWLKSVVDLNAYNGQSVMFRFRLASDDSVGRPDGWKIDNVSVKACVAEAEPEGPSLVFLPAITKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV69</accession>
    <name>A9AV69_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0496"/>
    <dbReference type="EnsemblBacteria" id="ABX03147">
        <property type="protein sequence ID" value="ABX03147"/>
        <property type="gene ID" value="Haur_0496"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0496"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2289814_0_0_0"/>
    <dbReference type="OMA" id="WYICKEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-502-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10901" checksum="3B0B863BD18C050F" modified="2008-01-15" version="1">MNNNTPASSQICPICNQPVQPMPRYPRYVCVDCRALAVDQHGRQVEFFNTGFLGTGCAGSYRDDQSDYPSDQCWINGQRCTAREARFGGIVIEVAAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC4</accession>
    <name>A9AVC4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1972"/>
    <dbReference type="EnsemblBacteria" id="ABX04615">
        <property type="protein sequence ID" value="ABX04615"/>
        <property type="gene ID" value="Haur_1972"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1972"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006968_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2001-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1152" mass="126512" checksum="44E6A99820BDE867" modified="2008-01-15" version="1">MNSVLLVPLYLDALVLPTEQAVAQAMTDFSRLPYSNGQHDINADVANVSEEIVRQPFAQSTLKAGVHLHWALPDSLTRGTQVGTTTNFPSVPNRWLVLRARGGGNTPLQIEEQWIVESDYLYPAGQFASSVTTPVAAEGNQQPFRYLGRRMPFSIWQEHDPQAEYLAQLTAVGYGEPTFAAFYPNCYSVFGFYDDSYTDDVPSDLQYLVLGWYNDINQDVVHSLVNSLQGSSNTDLSAALLAQLGWAVNVPDGSDFPDALCCYCQIQLSNPAAASTPSSPLQIAVGNTGTEALSAFLANTLNPSQPAAIEDHLEAVLMASFLDQQYLDVGASFLAARHEKSFNAIPSGSLWSVRPQSTSGSADSANATVLVNLPESLAHQLNQLNSLQHDYDRALELIEQQREQLFFDWYKYMLAAYPPAESRDDFPDVDLVRYFVEQKDLVPLANLLNSAGALSLQWDEVGNVIAASAGNSASNAIASGLAQQINLVLQAVADFNASTEVQAINQQYLLLITGGPRYWQPNEPVLLLSGAALEPTDRHGSDGELACQYVANLSLHPMTTSVVEQLANAVAAIKANATPQQVGFFSYDQVPWNPILLEWGVEVFPLDHHSNLDPNTSAYNPDFIFSNYSLSENAVDLAILPSQVAIAQSANLYSGWSILSSRAETQYQQQLNSYLAQYPDDTTVQQAAALVNDPTFHCLAQSLGGFNQALLMRKQTYQLAMADPLGFSDYQAWTDQVASAVANHNRSAPRMFSDFNPIRSGAMRLNRLRLVDSFGQLRDVAAEQIIRTQQMTTAGSDYLIWLPPRLMQPARVNLRWLSANQGDMEMNDAPITTPICGWVVPNNLDGSLMIYATSGAALGFIDAQVRWQYVPGGPNVEPTAIENRYLRQMVQYVLQRTSDFLRDFIVTIDNALDTIDPENAAAHTDLALLLGRPIALVRTSLDLELQGAPAIHQSWSALRLDLQQASRDDDGFAEVEFPIRIGEYQQLNDGVVGYWQELSDGSYADNIFYAPQSSDLPVDDPLIRTHDQADMAIRQTVNAAPRYLTMLFDPRGSVHATSGIQPVKAITIPADQYADALGAIAITFLTAPILTNQGAINLPLPVEAGYRWSWLEQPTSEWQETSEIGQVSPKATFEAPQTLHDGWLKLSPTNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVD1</accession>
    <name>A9AVD1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">G:T/U mismatch-specific DNA glycosylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1979"/>
    <dbReference type="EnsemblBacteria" id="ABX04622">
        <property type="protein sequence ID" value="ABX04622"/>
        <property type="gene ID" value="Haur_1979"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1979"/>
    <dbReference type="eggNOG" id="COG3663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094865_1_0_0"/>
    <dbReference type="OMA" id="QQYYAHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2008-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026353">
        <property type="entry name" value="Hypoxan-DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04274">
        <property type="entry name" value="hypoxanDNAglyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="18690" checksum="6A601646447D16E2" modified="2008-01-15" version="1">MPKFALPAIVHSTSRCLILGTLPGDQSLAAQFYYLHPRNQFWRIMQAVFADEPGLTSVTRAAFLARHQLALWDVLHAAERVGSLDTAITNPIPNDFQTFFTANPAIQKVGLNGMKAQQLFMRLVWPNLTSELQSRLELVGLPSTSPANTQAFAKKVEAWMWLRNALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVG9</accession>
    <name>A9AVG9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2017"/>
    <dbReference type="EnsemblBacteria" id="ABX04660">
        <property type="protein sequence ID" value="ABX04660"/>
        <property type="gene ID" value="Haur_2017"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2017"/>
    <dbReference type="HOGENOM" id="CLU_1037354_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2046-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29536" checksum="5209ACFC5D5FC96E" modified="2008-01-15" version="1">MATNHDDFLYQYQETPDPDFTTRLRDQLLAVDRVERILPPTTREAGIVHLAHGMRRRSWSGRIRALIGGVALLGTLMVTPLHVLATDILYQLGLVQITNDPTYADMIVGGQTPTPQPTSIPQVSFTFDTEMTDLATIQSQAGYSVYQLNGLPPGSRVVDRDIQHVVDADYATATMYQLKGQLRTLILVQAREGKLFTQMPVGQAQTESVTINGHAGVWIEGFTFLDQEAGVMESNNLIWNADGFTFYLSGVPSKEEGLLIAASLELTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW67</accession>
    <name>A9AW67_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein HSR1-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2077"/>
    <dbReference type="EnsemblBacteria" id="ABX04717">
        <property type="protein sequence ID" value="ABX04717"/>
        <property type="gene ID" value="Haur_2077"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2077"/>
    <dbReference type="eggNOG" id="COG0370">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036606_1_0_0"/>
    <dbReference type="OMA" id="ACSYQLP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2105-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="3">
        <location>
            <begin position="253"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="543" mass="57956" checksum="68AD4B36DF3950BF" modified="2008-01-15" version="1">MTTAAIVVIGKENVGKSLVIRALTGAPVTSMNMRGSTVACETYIGTQHTFIDTPGIHRATDLAQTAEVLAQVTASDAVLLVAQATHADDDLRDLLPLAAGKRGVVALTFWDKLPDRPQAMRMVERLRVATGMACIPLDARAIPAVDATRLVTALTNPPPLVPLPSGFRTGWRIDAPEQLLGHRHLGPALGLLLLLLPALLAVWCATRLAGLADPLIQQALGPVVTWGTTLPSLLGSTLTGRYGILTMGVLLVVWALPTILIYALLLAMYKTSGLLERITSAVHPLTRPIGLSGRDLVRVVMGFGCNVPAIINTRACSTCSRATCMSIIAFGSACSYQFSATLAVFAAAGRSQLIWPYLAYLTMTTLIYARLIAPPAARAAHNPLVLEQRVFLQWPQPQAVWAEVRSTLGQFARQAVPIFVLITLVASVLEWLGALAVAEQALTPLMSLFNLPAHTALAVVMGSIRKDGLVLFAEGGLAQQLSSIQLLTGVYLAGVLLPCFVTVLTIAREQSWRFAVRLVLRQAAAAAVFALLLAWVGHWMHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA5</accession>
    <name>A9AWA5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chloramphenicol O-acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2115</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
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            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.28" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2115"/>
    <dbReference type="EnsemblBacteria" id="ABX04755">
        <property type="protein sequence ID" value="ABX04755"/>
        <property type="gene ID" value="Haur_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2115"/>
    <dbReference type="eggNOG" id="COG4845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093121_0_0_0"/>
    <dbReference type="OMA" id="WERRDNY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2143-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008811">
        <property type="term" value="F:chloramphenicol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001707">
        <property type="entry name" value="Cmp_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38474">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01059">
        <property type="entry name" value="CAT"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000440-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="24437" checksum="D1C477634DF39508" modified="2008-01-15" version="1">MRTIDLATWPRRQHFSFYQGMTYPHFSLCANVDIQIWYQAIKARQARLSTSLTYVFARAANEQVAFRWRIRGDNVVEHDRVDPSPTVLLDDDLFSFCVIPYRADYHAFSALAEAKVAEVKANPTITDEPGQDNLLYMTSIPWVSFTSMMHPIHLNPIDSVPRISWGKHTLEGQRRLMPVAVQVHHGLMDGLHIGRFYERVQAILDHPEDFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC3</accession>
    <name>A9AWC3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2133"/>
    <dbReference type="EnsemblBacteria" id="ABX04773">
        <property type="protein sequence ID" value="ABX04773"/>
        <property type="gene ID" value="Haur_2133"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2133"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_2_4_0"/>
    <dbReference type="OMA" id="ANERTAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2161-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="42"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="28219" checksum="B6B8BE1D910BD222" modified="2008-01-15" version="1">MANTQIRFEDGATYERYMGIWSQLVGAKFLDWLAPKTGLNWLDVGCGNGAFTEMVVERHQPSMITGVDPSAAQIAFARQRLANYPAELHEADAMALPLADNSVHAAVMPLVIFFVPEPAQGVAEMARVVAPGGSVSAYAWDMFGGGFPYVLLQQALIDAGISVPRPPSVEASQLSVMHELWLQAGLTKVETAVIKVRRNFVDFADYWETVTGAPSVGPQIRAMTTTQQQTVQTQLQASLPIAADGHISIEAHANAIKGVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD4</accession>
    <name>A9AWD4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2144"/>
    <dbReference type="EnsemblBacteria" id="ABX04784">
        <property type="protein sequence ID" value="ABX04784"/>
        <property type="gene ID" value="Haur_2144"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2144"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="IQLPYED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2172-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="16836" checksum="73EB75AE58E2B603" modified="2008-01-15" version="1">MPVASNEYFVPVVPSDASVIIVEDNPDNLFVLEILLREDLRVKYYNGRASGRQFFKLLEANPRLYPDLVLLDIQLPYEDGFTVFKNMLNVPQLKNTQVIAVTANVMPQDVAKARELGFNGLIGKPINRNRFPAQITRILNGESVWEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWJ6</accession>
    <name>A9AWJ6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="8">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4123</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4123"/>
    <dbReference type="EnsemblBacteria" id="ABX06755">
        <property type="protein sequence ID" value="ABX06755"/>
        <property type="gene ID" value="Haur_4123"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4123"/>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111016_1_2_0"/>
    <dbReference type="OMA" id="KCEKLHG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4169-MON"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006113">
        <property type="entry name" value="PTP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03367">
        <property type="entry name" value="queuosine_QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="15409" checksum="4A33BA1703CB5A14" modified="2008-01-15" version="1">MYAILTKQFRFEAAHQLPNHRGKCARLHGHSYLLEVSVRGLIQPTRGQSDDGMVIDLEQIKQLVNEIIIARVDHYNLNDFLSVPSTAENIAHWMWDQLEQQAPEFAALLWRIRLWETASGYVEISRAEREAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWJ9</accession>
    <name>A9AWJ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4126"/>
    <dbReference type="EnsemblBacteria" id="ABX06758">
        <property type="protein sequence ID" value="ABX06758"/>
        <property type="gene ID" value="Haur_4126"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4126"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145430_0_0_0"/>
    <dbReference type="OMA" id="EHYIWGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4172-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13158" checksum="5B8FC4712E68F2F1" modified="2008-01-15" version="1">MLMMINLKNAEHYVWGDGCDGWFLHKSAAFTLIQERVPVGKAEVRHYHEYADQVFYVLQGVATLEVDGIIHQLQAGDSLAIPVGAAHQLSNQGPDELHFLLISQPNSHGDRVLAPLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWK5</accession>
    <name>A9AWK5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4132"/>
    <dbReference type="EnsemblBacteria" id="ABX06764">
        <property type="protein sequence ID" value="ABX06764"/>
        <property type="gene ID" value="Haur_4132"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4132"/>
    <dbReference type="HOGENOM" id="CLU_2355868_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4178-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="11452" checksum="EBAF923B01468965" modified="2008-01-15" version="1">MIKVLLLGLVLCAVVLIVGLVIAAFVAKKVLRTRNLKGLYNQFAYRFKGSKHHYPSRNQYYQSHDYNHYRPKHKKKHYYGHRHGHDDDYDDDYDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWZ5</accession>
    <name>A9AWZ5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminodeoxyfutalosine synthase</fullName>
            <shortName evidence="6">AFL synthase</shortName>
            <shortName evidence="6">Aminofutalosine synthase</shortName>
            <ecNumber evidence="6">2.5.1.120</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Menaquinone biosynthetic enzyme MqnE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mqnE</name>
        <name evidence="8" type="ordered locus">Haur_2163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-[(1-carboxyvinyl)-oxy]benzoate + H2O + S-adenosyl-L-methionine = 6-amino-6-deoxyfutalosine + H(+) + hydrogencarbonate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:33075"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64286"/>
            <dbReference type="ChEBI" id="CHEBI:76981"/>
            <dbReference type="EC" id="2.5.1.120"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. MqnE family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.120" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2163"/>
    <dbReference type="EnsemblBacteria" id="ABX04803">
        <property type="protein sequence ID" value="ABX04803"/>
        <property type="gene ID" value="Haur_2163"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2163"/>
    <dbReference type="eggNOG" id="COG1060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040406_0_0_0"/>
    <dbReference type="OMA" id="HIKAYWA"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102573">
        <property type="term" value="F:aminodeoxyfutalosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00993">
        <property type="entry name" value="MqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022432">
        <property type="entry name" value="MqnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03700">
        <property type="entry name" value="mena_SCO4494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="56"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="41269" checksum="19388A2F3B7CBFAA" modified="2008-01-15" version="1">MAILLAKSPLSDIAEKVEAGERLSFDDGMRLYQTNDILALGKLADTVNRRKNGDVVYFVQNHRITPTNVCAFHCNFCSFRRNGNEPDAFVRTPEQIIDHVGRLFSERTREFHIVGGLVPDLDVEYYADIIRELKDHYPNVHVKAFTAVEIDYMAQISHLDWRTTLEILRKAGLDALPGGGAEIFHPAVRRKICPEKVDGDGWLEIHGIAHELGIKTNATMLYGHIETLEQRVDHLLRLREQQDKTGGFVTYIPLAFHPENNNLGRVKKLDWTTGFEDLKNLAIGRLLLDNFAHVKAYWISLTPRLAQVALSFGVSDVDGTVIEEEIYHAAGAKTEQGISRAELVHLVTTAGKTAVERDALYNHIAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB9</accession>
    <name>A9AXB9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Biotin carboxylase</fullName>
            <ecNumber evidence="6">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4207</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4207"/>
    <dbReference type="EnsemblBacteria" id="ABX06839">
        <property type="protein sequence ID" value="ABX06839"/>
        <property type="gene ID" value="Haur_4207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4207"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_0"/>
    <dbReference type="OMA" id="IGPKHYS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4254-MON"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="2"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="121"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="512"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="588" mass="63711" checksum="4F89B17398E341FD" modified="2008-01-15" version="1">MSFDTVLIANRGEIALRVMRACKELGLRTVAVYSEADRDSLHVRYADDAFLIGPPPAVQSYLQTETILDVARRSGAGAIHPGYGFLSENTDFVRTCDAAGIAFIGPTADAMDLMGGKIHARQVALRAHVPLVPGTTEAVESVAEALELGEQYGYPIAIKASAGGGGRGLKVAYQPEEVEFAFESARREAEAAFKNGELFVEKYVLDPRHIEIQILADQYGNVVYLGERDCSVQRRHQKLIEETPSPAVSPELRRTMGECALRLCRETSYVGAGTLEFLLAPDGQFYFLEMNTRIQVEHTVTEMVTGIDLVQAQLRIAQGEKLWFTQEEIQLRGHAIQCRINAEDAAAGFRPALGTISAYNEPKGYGVRVDAGVEQGTTIPPYYDSMLAKLVTWGATRGEALQRMRRALNDYTIEGITTVIPFHKLALAEPAFEHGDVTVSFIPRYLEAKLKQLPSATPSTTEPAAEQPSRELMVEVNGRRFAVRVAGEGLNTPIASNKAAAPTRHRAANKKREVATDPNAVICPIQGTIVAIKTSVGAAVEAGQVVFVVEAMKMENEIATPRAGTIATINAEVGKSIEAGSVLATLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS4</accession>
    <name>A9AXS4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2250"/>
    <dbReference type="EnsemblBacteria" id="ABX04890">
        <property type="protein sequence ID" value="ABX04890"/>
        <property type="gene ID" value="Haur_2250"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2250"/>
    <dbReference type="eggNOG" id="COG1876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_917555_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2278-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735312" evidence="2">
        <location>
            <begin position="24"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="VanY" evidence="3">
        <location>
            <begin position="98"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="303" mass="32982" checksum="27F04469842193C5" modified="2008-01-15" version="1">MKFLLVALCGLGLLVGCGTVSQAAITDRQVPLQPVLIAPSATPTPKPTRTSVPTPTLTPRPTNTPTPIAVPLLPTLDPEAELLDLRLAGVRGSRSGQLLRREAVADLKALIDAARRDGFVLEIRSAYRSYAEQASTFEGWVQYELSSAAQTGKPISRKQAIAYAATYSAKPGTSEHQTGLTVDLLPQGAPEIGFRIPDPLKDWLNANAYKYGWVQSYPIKYRDGELITYELMGYTSEPWHWRWQGRDSAKSLYDQGYLDTDSLLVPPTLPRICDAEHDPCMILSAAPAKLVAIPTSTPIAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU2</accession>
    <name>A9AXU2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2268"/>
    <dbReference type="EnsemblBacteria" id="ABX04908">
        <property type="protein sequence ID" value="ABX04908"/>
        <property type="gene ID" value="Haur_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2268"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_4_1_0"/>
    <dbReference type="OMA" id="GPSHWEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2296-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="35"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="45945" checksum="D2A06A44FB3EB853" modified="2008-01-15" version="1">MWQQRCWLRRLAYLMIIGLLGGCISTSANQQPLVITFGASISITGKTAKEGEYVRDGYQFFVDTLNAQGGILVGGQRYQLRLRYYDDESNLERTAELYEKLINHDQVDFLLGPYGSDATSVAVAIAEKYHIPLVSGHGSASSIYANNYHYIFSVQTPARHYLNGVMDAVLAADPSLKTLALLSETDSFSQDVAQGVRDYAQQRGLNVVYHGDYPSDARDVSHHLNIIKQLQPDMLLGAGHLQEALLIVKQAKSLDLSPKAIGLSVGPLLPQFRANLQHDADYILGPTQWTPALDYHGDDSWQTPAAFAQAFRQQYPQYKSVPYQVAESAASLIVFQRAFERAGTIDRLAVRDTIKGLKLDTFFGPIQFDAQGVNSEKPMAVEQLHPDGQKYTVFPQAVAEQPLLYPMPTWSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU3</accession>
    <name>A9AXU3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04909">
        <property type="protein sequence ID" value="ABX04909"/>
        <property type="gene ID" value="Haur_2269"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2269"/>
    <dbReference type="HOGENOM" id="CLU_2046420_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2297-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="120" mass="13269" checksum="321552085D4D6A3C" modified="2008-01-15" version="1">MSLATIERLLDAVLPDQQVLADTTAILESLVQDGSVAVLVTSYGGRVSPLTIPYPVPLTVIRKIFQRRFVGAATWTMSAMVALGTVELDHGSIRAQYHFLDLDYTAERTIVNVEWFDPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU8</accession>
    <name>A9AXU8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2274"/>
    <dbReference type="EnsemblBacteria" id="ABX04914">
        <property type="protein sequence ID" value="ABX04914"/>
        <property type="gene ID" value="Haur_2274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2274"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_0"/>
    <dbReference type="OMA" id="SYPRRVW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2302-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="131"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="131"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="26127" checksum="0A0A1A6FDEE862F0" modified="2008-01-15" version="1">MSNTINVLVIEDEAPIRRFLRASLPSHGYHLIEAENGEDGLLQAAMQRPAIIILDLGLPDLDGLQVTQRLREWTNTPIIVLSARGREDDKIAALDAGADDYLTKPFGMGELLARLRVALRHLHQHGGEKGEPVFQVGALRVDLVRRQVFVAEQEVHLTPNEYNLLTTLVQHAGKVMTHRQLLREVWGPAYTEENHYLRVYMGQLRHKLEADPARPRYLLTEPGVGYRLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY87</accession>
    <name>A9AY87_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylated-DNA-(Protein)-cysteine S-methyltransferase DNA binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4337"/>
    <dbReference type="EnsemblBacteria" id="ABX06969">
        <property type="protein sequence ID" value="ABX06969"/>
        <property type="gene ID" value="Haur_4337"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4337"/>
    <dbReference type="eggNOG" id="COG3695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_5_0"/>
    <dbReference type="OMA" id="PRHSRHV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4390-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="110" mass="12647" checksum="5DFC3C998881798B" modified="2008-01-15" version="1">MSNEFLTAIYQTLKQVPAGRIVNYGRLALAAGYPGYARAVGKALHALDEQYPDVAWWRVVNREGRISTNCPVHTAIEQRQRLEAEGIEFDQRGYISWQRFGWLETSELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB9</accession>
    <name>A9AYB9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0853"/>
    <dbReference type="EnsemblBacteria" id="ABX03501">
        <property type="protein sequence ID" value="ABX03501"/>
        <property type="gene ID" value="Haur_0853"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0853"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_3_0"/>
    <dbReference type="OMA" id="LNWMRAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-867-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="27474" checksum="0130CBFDA9DDE030" modified="2008-01-15" version="1">MSYQLISISQQAAVTTVSLNRPELHNAFNPELIGELRQALTAIATDSSTRVVILTGNGPSFSAGGDLSWMQASASYTAEQNIADAENLDAMFDLLNSMPQPVIGRINGAALGGGAGLVACCDLAVAVEQAKFGFTEVKLGLIPAVIAQYVVPKIGVSQSRALFISGERFSAERAFEIGLIHAITSEDELDQTVGYLVERMLSGGPQAMAQAKKLVQAIWEMERSAAKRYAIEAIAQARTSAEGQTGLAAFLNKRKPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD2</accession>
    <name>A9AYD2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0866"/>
    <dbReference type="EnsemblBacteria" id="ABX03514">
        <property type="protein sequence ID" value="ABX03514"/>
        <property type="gene ID" value="Haur_0866"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0866"/>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_30_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-880-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="930"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1908" mass="205732" checksum="2736435B5C338A89" modified="2008-01-15" version="1">MSHAIAIVGVACRYPDADSPKALWEMALAKRRAFRRMPDQRLNNLDYISSDPAALDSTYVEYAAVLRDYEFDRVRFRVPGHSFRSADMAHWLALDVADQALRDAGFADGQGLPRESTGVYLGNTLTGEFSRANTLRLRWPFVRRVVAAGLAAEGWSSEQRGQFLQQLEQNYKAPFPIVDAETLAGGLSNTIAGRICNHFDLMGGGYSVDGACSSSLLAITTACTALASGEVDVALAGGVDLSLDPFELVGFARAGALATDLMRIYDQRSAGFWPGEGCGFVTLMRAEDAYAEQRPIYAVIRGWGISSDGSGGITRPEVAGQVLMLKRAYRRTGFNIDQVGYFEGHGTGTAVGDATELQAIAKARLDVQNPNLPIAAVGSIKANIGHTKAAAGIAGFIKATLAVHSAILPPTTGCEQPHSALETLRVLATPEAWPEQTPRRAGVSSMGFGGINAHIVLEQAEQAKPAYNWQPFIGQNHSQDLELIVVAKADRQALLTELQQLRQRAEQLSYAELGDLASHYAQTNSTGLARAAVIANNPRQLAAKLDLLIAQLEAGVNQQLDFKQQIFIGIGKKQPTLGLLFPGQGAPQANPKSAVFQRFAELNRFLSQAQLSQAEQINTANAQPNIVRASLAGLHLLKQFKLHASAAVGHSLGELSALHWAGAYDQASLIELAQARGHAMANYGQANGGMASIGADPSTIKSLINGDQAVIAGYNGPQQTVIAGSREAMNTLVERAQQQGLAATNLAVSHAFHSPMMQPAIPVLQAHVANLSAQPLQSTVYSTITGTKLSAQVELGSLLSQQLTDPVRFVEAIDGLSECDLLIEVGPGTILSRLASECIGVPAVSLEVESNSLAGLFKSLAAAFVLGSPLDLSYLAQTRFSRPFDLRHEPSFLTNPCETAPAQLDDHQPSLSLTISPSAQLASPTTSNATDPLQIVRELVAARSELPLASINDSDHVLGDLHLNSLTVGQIVSEAARLLGLQPPLAPTSYANATVGQLAQAISELQNSANTPSVTPGYPGIAPWVESFVITLVEQPVPAPKISRLASQWQLFHEPNYALAHALSSAFQQQVGQGVVVCVGETVDAATIERLLEAARFALSQSNPQHFVLVQHGEGLAGFARTLALENPQLAVAAVHVPIDAPQACDWIVAEALASTGYLEAHYEHNGRRTSPILQLLHLGEDSELPLGPDDVILATGGGKGITAESVYAIAKASGAKLALLGRSQPSNDQELAQNLERMQAAGITVGYWAVDVGDAASVQQAMNTIQAQLGIVTMVLHGAARNVPSLIRNLDRASFEATLTPKVQGLNNVLAALDQQQLRFVVGFGSIIGRMGLAGDADYAVANEQMRRIIEQGQHDYPNCRWLSIEWSIWSDVGMGVRLGGVDQLLQAGISPIPPDTGINLLLRLLANPIASSHVVVTGRYGELPTLQTIQPELPFLRFLERQCLYYPQIELIVEAQLSSANDPYVVDHSYHGEQLFPTVIGLEAMAQVAMALTGSQQIPTFEQVALQRPIVVPANELLTIRICSLQVAKGVVKLAIRSQETLFQVDHFSAIARFDQPANFGAAPNQIDWPVLTLDPVADIYEPLLFHQGRFQRLQNYRYLTARHCIANLATRNEPWFGRYLPQRSVLGDAGMRDALIHALQVCVPYAQVLPVAVERISCQSPSQPSDWTIYAQERAWDGNMFTYDVIAVDQQGNVVEEWQGLRLQLVEGSGYKDAWPASLLGAYLERQVRQVLPHTSLTIAVETDPALERQQRSDLALQRAIGQRQPIQRRSDGKPEVADYVVSASHYGQLTLAVAAKEPISCDLEPISPRSVEQWLDLLGAERMQLAKLIQQQTGWTLDQAATQIWTALECLSKVGAAFDSPLRLEPQAANNWLVLQTGQYRIVSQQLNVRDTELPVVVSLLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH2</accession>
    <name>A9AYH2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0906</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0906"/>
    <dbReference type="EnsemblBacteria" id="ABX03554">
        <property type="protein sequence ID" value="ABX03554"/>
        <property type="gene ID" value="Haur_0906"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0906"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_0"/>
    <dbReference type="OMA" id="NNRANEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-920-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="310"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="528" mass="59114" checksum="92480107B626CD0D" modified="2008-01-15" version="1">MMKFWLRWYGQAELWRAFAIMLLFDGLCLAILLAIIYLLPVEVFVLMTGGFFVLGVGTVIFGLSLVLSEGGFWRQLLLDLGAFGLAMICLVGLGGLISWHELSRIMSPWNDGDFAQSFPDMLIFFALHGITFLGTRFLMRVWRWWNRLRKRSLLWTLTHDQLTIVFVLMLIFGMGMVLLSIQLRSEELSQSNDAVVFLIEHVVQYSLLGSIYGVLMVIGLFVFLPVAMLLSYMLVRRIMQRIAALANATTALREGDYSSRIVVNGTDEIAQLQANFNAMAEQLSTTVNALKTERDRVAALLDDRRALVASVSHELRTPVATLRGYLESSLQTEQALAPQVQRDLLVMERETLRLQQLIEDLFLLSASEVGRLTLKLEAHAVAPLINRIVQTVQPLAWRQSRVEVLADCAAELDQALIDPQRFEQILRNLLHNALRYTPPGGLVVVQALNQANSIDIYVRDTGSGIDPTELSAIWQRFYRANNRANEQYQGAGLGLALVKELTESMAGSVAVESQLGVGTSFCICFPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ6</accession>
    <name>A9AYJ6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4388 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0930"/>
    <dbReference type="EnsemblBacteria" id="ABX03578">
        <property type="protein sequence ID" value="ABX03578"/>
        <property type="gene ID" value="Haur_0930"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0930"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037352_0_0_0"/>
    <dbReference type="OMA" id="IIMEGIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-944-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4388" evidence="1">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29772" checksum="3E0C5399A95B162D" modified="2008-01-15" version="1">MALEGNLRDLSISDLIQLVDLSKKTGATHVQALQGDESVEGYLYFRDGRITGATLGNLEPLEAALTFFTFHEGQFRFYEQAVPPPTITSSNEMIIMEGIDRQDRWAEIEQFVPNTNIVLRLVQNPDTGSRDINLAADEWRVLTMINGKNTVALIAERTGLGWFRSCEIVANLLRNGLIEKKELNLAESLFPQFEEMARGALGNSASVLLSEAYRRVGIEPTANNASNEQVHAAISAFEESIRLLVGRPNATQLADKLRERAVRILGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYM6</accession>
    <name>A9AYM6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05004">
        <property type="protein sequence ID" value="ABX05004"/>
        <property type="gene ID" value="Haur_2364"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2364"/>
    <dbReference type="eggNOG" id="ENOG5030IRV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1141344_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2392-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="28537" checksum="A7E688B3789DD60B" modified="2008-01-15" version="1">MATQQKYKNIRRIENVEANSYGWWVRVRIDGELFSKFFSDNAFNGSGNALRNALEYRDSIKRERGRPHIETVDPEVHYKGISRIDREIKRTHGWYVRVFYKGQQRVKFFSDMLYDGREGALAAALDFRDEAERELGKPRTDRPVVTVSRRNATGKIGVTRVRRKDRNRKGEVYLRDVYEITWCPRPNEIHRTSVSVRKYGEEEARKRAFMIRDNKEREIFGKVVSQTPTAEELAILDAGDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYP5</accession>
    <name>A9AYP5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2383"/>
    <dbReference type="EnsemblBacteria" id="ABX05023">
        <property type="protein sequence ID" value="ABX05023"/>
        <property type="gene ID" value="Haur_2383"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2383"/>
    <dbReference type="eggNOG" id="ENOG5031B5G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_575909_0_0_0"/>
    <dbReference type="OMA" id="FERMSHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2411-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="474" mass="53710" checksum="217800FDFF0CE23C" modified="2008-01-15" version="1">MSSLEQHVDTLFEDGAALLNGNPSQKLGQQLTFNGLATPPQLIARRFLGKLVDVLVPPAFTAILSGPQGLRRCLTSGSYNLWDIPRGPVMVQWVSMSRMRREIGPIEGWSADKWRVRFTVVVDFEVCDPYLIASHQAPLTVLEDVVRSAAMQQFERMSHEALTGYDPEIGGIDRPALRMFEQLSQEPALAGLTLIRLQILDRAGDLRRIEAATETAVAIAQLEESTRLQRAEDQAALLTIDGQVLRQSAEAALRMAATIDEGREQLARHDIAAQRHALNAQLHVLEANMRAQVAEIAREEQAWQHEQQRLMLEWQSQIQAQQSEQTHDQQYQMLDLQHRFEALHAERAHEVEERRHQRERELRAMQQRHEQVLINQRERLEHWRSQHERSLQLTQQQHQEQLALIQGTTTIASQAAGYLAQFGMPSRRIGSNDLAHDPTLIAGEGLRSLRMLQEQLQPQITEPAAPSEASDASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ9</accession>
    <name>A9AYQ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2397"/>
    <dbReference type="EnsemblBacteria" id="ABX05037">
        <property type="protein sequence ID" value="ABX05037"/>
        <property type="gene ID" value="Haur_2397"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2397"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_8_3_0"/>
    <dbReference type="OMA" id="FTGWWNE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2425-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734432" evidence="4">
        <location>
            <begin position="21"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="121"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="597" mass="66027" checksum="FE3D4F62B1D491CC" modified="2008-01-15" version="1">MKLRFPALMLLVIIFTSMLAACGDASTLTPQATQAPSTTAPAATATEAPATGSTDPTAEPTAAATTDTGSTSSDGKLFLTVSDQQQSTWVRNFNPFASDNRWPTAAGIYEPMFIYNIATGKIEPWLATEWAWNSDNTELTFTIRDGVKWSDGEAFSSKDVAYTLNLMKENEKLQGNGRAAMRFVDSVAADGNKVVVKFSEVSTIALYDIGHQMIVPEHIWSKIADPVTFTNETPVATGPFTEIIRFQDQIWELGKNPNYWQAGKPYIDGIRQPAYPSNDAANLATINGENDLASNFIPDVENTYVAKDPENNHYWFPPVNAPVMLLLNTTKAPFNDPNVRKAISMGFDRQQITEIATYSYNGPSDATGLPESFADWKNPEAVAAGDWVNFDVEKANAMLDAAGLTRGADGIRVLPDGTPMTYDINVVSGWTDWVTTDQIIAESLKEIGINATTRTYDFSAWFDKVQKGEFDMSIGWSNNAPTPLQFYRGLMSGETADTPIGEANGDNWHRYGNPKVDELYSQFVKTSDPAEQKKIMNEIQMIFVQEAPAIPIMPNIYWGEYNTKRFTNFPNEENPYVLLSSFAQPDRLILLTNIKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYZ8</accession>
    <name>A9AYZ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4406"/>
    <dbReference type="EnsemblBacteria" id="ABX07038">
        <property type="protein sequence ID" value="ABX07038"/>
        <property type="gene ID" value="Haur_4406"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4406"/>
    <dbReference type="eggNOG" id="ENOG50335T7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130293_0_0_0"/>
    <dbReference type="OMA" id="HYDHACV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4460-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050485">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010187">
        <property type="entry name" value="Various_sel_PB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07355">
        <property type="entry name" value="GRDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="18913" checksum="7C46AFCB95C319FE" modified="2008-01-15" version="1">MRRTFNQLGAWLYRAMPGLGQRWAKRFQVQAVAAQIPWTPLHGTLAQQRISLITTGGVHLRTDPVFDMHDPHGDPNFRLIPATASPNDLMITHDYYDHRDADRDINIVLPISHFQQLAARGTIQSLGPCYSFMGHITDEHIETLIKQTAPTIARNLREAGVTAAVLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ20</accession>
    <name>A9AZ20_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4428"/>
    <dbReference type="EnsemblBacteria" id="ABX07060">
        <property type="protein sequence ID" value="ABX07060"/>
        <property type="gene ID" value="Haur_4428"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4428"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1041195_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4483-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29378" checksum="1C754B9F10D413BD" modified="2008-01-15" version="1">MSYRAFVVEDSEVHATLAELLLQEAGFEVTIWRSIRQAWHWFEHDQTKQPMLGLLDIKLPDPTLPRLESTVLAAAISDAVAQGRHAPVHLVAISSELTPQREWAALATGCSAVLSKPLTPLKAQWLAELITQPMPTLSDEISAVAFRQGQLDVLNLLELQQRPPRRVWQIEDVRNLLAVLTAGFHVGEQGRQAGLNLQHEFGGSTAAHVALRACLPLLESEQARLLGLLLHGVAQQTIAGRLGLGRRKLEGQIEQLLQQLAILLSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ44</accession>
    <name>A9AZ44_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0942"/>
    <dbReference type="EnsemblBacteria" id="ABX03590">
        <property type="protein sequence ID" value="ABX03590"/>
        <property type="gene ID" value="Haur_0942"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0942"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1576338_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-956-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="19005" checksum="9E7FA29D977C5442" modified="2008-01-15" version="1">MAQPANDSAIIALLQRGDQQTWRMLAEQWSGELYNLAWGAVYQADLAQNIVNKVWATAIRTIHSVDQRLGLRLWLYTISCHVILDHWRDYGHTPQTASLISELQHLPEAMHLALLLQLRHNESVAMIAEILGRTQRATEQLLQQGQQRLKLAGAEEFYGINQAAAAAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ45</accession>
    <name>A9AZ45_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0943"/>
    <dbReference type="EnsemblBacteria" id="ABX03591">
        <property type="protein sequence ID" value="ABX03591"/>
        <property type="gene ID" value="Haur_0943"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0943"/>
    <dbReference type="HOGENOM" id="CLU_1728848_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-957-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="17100" checksum="6923AFB8AE7C8045" modified="2008-01-15" version="1">MLDNWLGRDKASPQAPKEEPMSSNDASRPTPPPRQPDDGLIRRPRPNDRDNAFNLALEDLRRQVQLLYESIGALAEHYNETGGDPRRARDCRDCSHFRVGLHVPCVMGVDPHTAPYLAVRCPKFEETSENRKLINRDEAGFNAAVRRAREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ52</accession>
    <name>A9AZ52_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0950"/>
    <dbReference type="EnsemblBacteria" id="ABX03598">
        <property type="protein sequence ID" value="ABX03598"/>
        <property type="gene ID" value="Haur_0950"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0950"/>
    <dbReference type="eggNOG" id="COG0127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082080_0_2_0"/>
    <dbReference type="OMA" id="DCFADDT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-964-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="21808" checksum="E44B12B3AE4043BA" modified="2008-01-15" version="1">MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQISGLPTLADDSGLEVAALDGKPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARFVCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVFYLLDYDKHLAELDPEEKNRISHRGQACALAREVLELLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ67</accession>
    <name>A9AZ67_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0965"/>
    <dbReference type="EnsemblBacteria" id="ABX03613">
        <property type="protein sequence ID" value="ABX03613"/>
        <property type="gene ID" value="Haur_0965"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0965"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="FTAYDTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-979-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14395" checksum="DC21C0C2E8D1E206" modified="2008-01-15" version="1">MTKRILIAEDDTAIAMTLMIGLRSIPDVEVVRAYHGEEALNIWLHEPCDILLTDHHMREMSGLDLIRALRSQGATQPMLMITAYDSVKLQREAREAGATELIAKPFFIDQLIDKVSEKLLDVSVVNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH2</accession>
    <name>A9AZH2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR system Cms protein Csm4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRISPR-associated Csm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2478"/>
    <dbReference type="EnsemblBacteria" id="ABX05116">
        <property type="protein sequence ID" value="ABX05116"/>
        <property type="gene ID" value="Haur_2478"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2478"/>
    <dbReference type="eggNOG" id="COG1567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062371_0_0_0"/>
    <dbReference type="OMA" id="YFSHFEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2506-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005510">
        <property type="entry name" value="Csm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040932">
        <property type="entry name" value="Csm4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17953">
        <property type="entry name" value="Csm4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01903">
        <property type="entry name" value="cas5_csm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Csm4_C" evidence="5">
        <location>
            <begin position="235"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="37009" checksum="9D91DF276C7A344C" modified="2008-01-15" version="1">MEFNLIRLKPQAAFHFGMQGIDMEVVSETCPSDTLYAALFWQALQQGQRWASEPSNPPFTISSCFPYVDGIQLLPVPMLPPLPSDKQNPGERKQFKKVRFVSSEIFINLLAGTHSLSHYFRPTNGVALQNGSVLVSQAEFSANKWAVADPLWKIESIPHVAVDRWSNASAYYETGQVRFAEGCGLAILALGDIKQLMSLLHQVGIDGLGGRRSKGVGMFEPELQTETLDLPAATSDSVIVLSRYLPSAAELAAGVLDLPAAYSLEDVTGWMYSPAAKAQRRKAIWMIGVGSRLNRTGLAHSIIGSSVDVAPTYDTPNAGVNHPVWRHGLALTVGCSVGDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI4</accession>
    <name>A9AZI4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05128">
        <property type="protein sequence ID" value="ABX05128"/>
        <property type="gene ID" value="Haur_2490"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2490"/>
    <dbReference type="HOGENOM" id="CLU_1287368_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2518-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735137" evidence="1">
        <location>
            <begin position="18"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="214" mass="23195" checksum="9D41CEF767A04213" modified="2008-01-15" version="1">MRVRKLFVGLLVGGLLAACGNQTGPLSTNASTPTDRPASTETMVEVTVIYLDADDEYESSFEFASAKEPVIKGERLIMAGTDVSLSFKIIDFVRGEQALATIATIDPAYAGLPAGYEVGLVRAEITHGNVRTEPVVFDGSMIALLVLTNGEYQPVKDQQGLPCCFEPRFDTPVAKGDQLEVYFPILVATDDPNPLLVINRDQSDNEDARHFALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ9</accession>
    <name>A9AZJ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2505"/>
    <dbReference type="EnsemblBacteria" id="ABX05143">
        <property type="protein sequence ID" value="ABX05143"/>
        <property type="gene ID" value="Haur_2505"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2505"/>
    <dbReference type="eggNOG" id="ENOG5032UYT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_979606_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2533-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="29408" checksum="9A8AAB73A66B16B0" modified="2008-01-15" version="1">MATSKPQLSPLVRIMFIVVALVLVAGVSLLIAPSLVGPRWPWALRPFATRFLGAVYAAEMVAVLFTLVINDWSVARLTIPQAVTFTTVVTGASLVWINNFDFSRVIVWLWFIIYTLPTLALGWFWWQYRAWPAVNPQPLGRLRSILLIEAAVLGSYGLASIIAPNWATAFWPWKIDAFHAQIYSALFMTGAIGAWIVAGGGNRYELLTLGWSQVVLGLGVIAALAIVEFGPDNLSVPWASIGTIIWVASFGLIALVGGVLIGRGMRQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU6</accession>
    <name>A9AZU6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4518"/>
    <dbReference type="EnsemblBacteria" id="ABX07150">
        <property type="protein sequence ID" value="ABX07150"/>
        <property type="gene ID" value="Haur_4518"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4518"/>
    <dbReference type="HOGENOM" id="CLU_1358876_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4573-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="201" mass="22359" checksum="E41510DC3758B60B" modified="2008-01-15" version="1">MGLLASLFGCGSSAVPEAVRNGLDEQSIQTIGTLDISPWLGDKPRYRRLSLIRAQTVAGEPTTIAYLEPNADAAAFALPLTQTFPEAPLQTALFEIDGYRLIVGLVDDRVMGELTTIEFEREEPDQTRWLEALKVSKLNKRTFVIPIAPNEQAQWPTVQRIAVNTRESRQRGVDDRNASGHEWEHRYSNPIAIDSTFAVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZX9</accession>
    <name>A9AZX9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="15">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Haur_1038</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="15"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1038"/>
    <dbReference type="EnsemblBacteria" id="ABX03686">
        <property type="protein sequence ID" value="ABX03686"/>
        <property type="gene ID" value="Haur_1038"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1038"/>
    <dbReference type="eggNOG" id="COG1085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029960_0_0_0"/>
    <dbReference type="OMA" id="HAIYYPP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1055-MON"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00608">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 15" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="16">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="17">
        <location>
            <begin position="181"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding" evidence="11">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding" evidence="11">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="314"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="10 14">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ABX03686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="39406" checksum="092687DDD9CE8B01" modified="2008-01-15" version="1">MNLSDTPHRRYNPLTDEWVLVSPHRTARPWQGQVEKTIPDQRPAFDPQCYLCPGVTRANGEINPVYASTFVFPNDFAALLPDSPNAALDDGLFQAHSERGICRVICFSPRHDLTLAEMEIPDIRLVIDLWASQFSELAAIDWIKHVEIFENRGAAMGASNPHPHGQIWANESIPTLVATEQRSQKAYFAQHQRPLLIDYVEQELARGERVVYANDYWAAVVPFWAVWPYETMLLPRRAVSTLAELSEAERDGLADLLSHTLIRYDNLFQTSFPYTFGWHNAPCDGEQYPHHVVHAHIYPPLLRSATVRKFMVGYEMLAQPQRDLTAETAAQRLRDLPSLHWTKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B009</accession>
    <name>A9B009_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dual specificity protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1068"/>
    <dbReference type="EnsemblBacteria" id="ABX03716">
        <property type="protein sequence ID" value="ABX03716"/>
        <property type="gene ID" value="Haur_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1068"/>
    <dbReference type="eggNOG" id="COG2453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1494290_0_0_0"/>
    <dbReference type="OMA" id="HCQYGIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1085-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="4">
        <location>
            <begin position="97"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20639" checksum="21F3843B5C87C281" modified="2008-01-15" version="1">MLAVLQHWFYVLRSHLVMGTRRLYRRLGGKVKPRTNQITEQLYLGGFFDLHDWQILHAQGVQVVVNLQAERQDQFGTLGNQGYLWLPTMDRQAPSPEALQQGVVFVQQAIQADHKVLIHCHAGMSRSATLCTAVLIAQGMDLESAWNLVKARRPIVHLHPWQRRALEQFARDWAQQGAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B072</accession>
    <name>A9B072_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2543</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2543"/>
    <dbReference type="EnsemblBacteria" id="ABX05181">
        <property type="protein sequence ID" value="ABX05181"/>
        <property type="gene ID" value="Haur_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2543"/>
    <dbReference type="HOGENOM" id="CLU_522504_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2571-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="373"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="521" mass="61163" checksum="113DD9D054E777EF" modified="2008-01-15" version="1">MSMNEIWTTQDQYYTYIKKIADNIFKDSNIIYEILIFGVKYHDRNQCSVILYPDNKNNIILSEMIKKKLMSSNKGIKKGVIPEKRSTNLDSNDISHRAMINSFLNAKKKFNLQNKNIKYRRKYNLDTYKLFNKNNKCFAYFSQVRDILGYDVYIIFNLDKKSSSNYHKFHDPREVGRGEIRSFIDAVIYSYLNKCVSVLESLFKDEIVYKNNEIISISNKILISSGESLLKGVIEILDIDKKDDEVQIDMFDLINSISQMSYENTYINGYLVLINDDKLKNMQYIFKLKDHKDYRINKSKTTRKLIQMARNNIVLATDSIFIYGLYYKNIIEQLKDVFIIKIIGQSKWELYYNKWMLMYVEYSIPRIITGINQDEIRNRIINAEFRQEYIDDIHRFILDVIEVALKERKGITLIFGNDVQEEIANNNIVCIKIEVRSIRDIFKSINSLLTIDGGILMDKEGRCYAIGAILQYGSSEQNDPARGSRYHAAKAYSEKAKEKNSRFVVVISEDGYIDFFPEPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F1</accession>
    <name>A9B0F1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_2622</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2622"/>
    <dbReference type="EnsemblBacteria" id="ABX05260">
        <property type="protein sequence ID" value="ABX05260"/>
        <property type="gene ID" value="Haur_2622"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2622"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2650-MON"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017752">
        <property type="entry name" value="G3P_DH_GlpA_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03377">
        <property type="entry name" value="glycerol3P_GlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="12">
        <location>
            <begin position="6"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="13">
        <location>
            <begin position="407"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX05260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="514" mass="56263" checksum="081BDEBCE0E77187" modified="2008-01-15" version="1">MLDSIDVLVIGGGATGTGVLRDLAMRGLSCVLVERRDLADGTTGRYHGLLHSGARYIGRDREAARDCAIENQILRRIIPHCIEDTSGYFVSTPQDPKRYAEEFLGLCFAAGVPAQQVRVSSLLQREPALNRGISHAFEVADGSADAFLTVEANVRSAREYGGQTLLYHEVINLIVEAGTVVGARLRNTLTGEEFNLACHYVVNAAGAWAGRIAAMAGIAVDIVAGKGVMVAFNHRLVNSVINRCKQPGDGDIIVPVRTVCVAGTTDESVPDPDDRSMLAHEIATVLDEGEILIPGLSQARMLRAWAGVRPLYREQATTEDRDLSRDFKVLDHAQRDGLDGIVSIVGGKYTTYRMMAERTVDLVAKYVQNTSACRTAEEAIPAPDQRRLFTVGAPLATIEAEQSYGDLICECELVTRQRLLDAWQAGATSIDDLRRDTRIGMGPCQGGFCTMRTAALAYEAQVADQQQSIEAIEHFLQERWRGIQPILWGDQLRQARLDEQIYLNLLNVNPEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G0</accession>
    <name>A9B0G0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Multi-sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4547</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4547"/>
    <dbReference type="EnsemblBacteria" id="ABX07178">
        <property type="protein sequence ID" value="ABX07178"/>
        <property type="gene ID" value="Haur_4547"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4547"/>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_51_0"/>
    <dbReference type="OMA" id="ECESIAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4602-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="349"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="543"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="613"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="856"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="973" mass="109117" checksum="F5D796261F1AEAE8" modified="2008-01-15" version="1">MKLLWLFSTLAEFMNSFSATSFQPAMEQPTLAELTQTIARLEAELAATKQALLASEQRNLQFFQQTQAIELIVEPDTWRVLAANAAACRFYGYSQAEFSNLNVRDLNVLTSKEHRVAIRNGELGGSNRYEFRHRLRSGMVCDVEVYITPFEYQQQPALFCLIHDVTAHKQTIRQMQRQNAYLGSLHDVTLALIDQAALPDLLEIILWKATDLVGSEYGVMYIRSADGQAMESVVSRGAINVIQHIELGQGAVGTVGLSGQPLIIDDYSAWSERLFTPQDGFGNGLLVLPLFREQTVAGALAIIYEPSQIQISITMLEMVQQFARFASLALEKHMLYTAAQTELAERRRVEQQLRSLNERFELAQTVLNGGIYDWDMIQQTTVVNRSFTTVFGYTSEEVASSPTWWEEHLHPDDRELFIQRTADIFAGHSDVFSAEYRFLDQHQHYRFVQDRGHVLRDPDGQALRMVGTLIDISEEYRHIVEMLPLPLFVVQDDRIVYANQAGLALTQTTSSELLSQSVLSGLRPQDPDDFYVLIRHASTMPTSFIETTFLRRDGTPIYGECSTSAILFEHRNSVQVIIRDISERKQAEQKRLEIEQHFSETQKLESLGVFAGGIAHDFNNVFMSILGNTHLAMLELPEQANLRPLLAEIEQSAKRAAQITKQMVAYTGQNLDVRRSLMINELVQTSIRLLPSSLTQQRHIQSNLADNLPLIEGDQQHLRQAISNVLINALEASSSGTLTVTTSLRDLQGAPEGHTYTTGTFLPAQYIAIEISDQGLGMDHATISRMFDPFFTTKFTGRGLGLAVTLGIVRGHRGGIAVKSRPQQGTTIGIYLPIMTAVQTELASEQPALVDSGPGKILVIDDEPDVRIVIDRILRRLGYETLLAEGGNRGISLFRDHHQEIAGVFLDLTMPDLDGQSTLEVLKQIQPEIRVVIMSGYNEQQVSQQFGTTGTTQFLAKPFMIEEIRDKLTALRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L4</accession>
    <name>A9B0L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4601"/>
    <dbReference type="EnsemblBacteria" id="ABX07232">
        <property type="protein sequence ID" value="ABX07232"/>
        <property type="gene ID" value="Haur_4601"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4601"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4656-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="81"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="37868" checksum="EAD2DF25DF8F548E" modified="2008-01-15" version="1">MFKNLPLTFGLSIVGLMLLIAIFGPSLAPHDPVEEHRAFRYEGQLYGGPPMAALPPFSHPEYPLGFDDISRDLLSRLLWAVRPTLVLCTIIAAVRLLLGLVVGGVVGFLGPRVASWLDTITTITSSLPILIVALGYLIWTGGSAVIVYQGVRPITANNAGLTAFIVALCMTGWVNSASVVQGYVQKILHAPYLESAQAIGLNRWQITRRYILPQVWPLLPMLLASELTAVTLIVAELGYLGYYIGGSYIYTDKTTDSPLPDIVKQKAGQPELGQMLSDFFGQYSRAPWVSIFAGLLMVLLLVGFTLTSEGLRRSLDITRPRRWSWRNLLPRKTSKTSKSKLNQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X4</accession>
    <name>A9B0X4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1196"/>
    <dbReference type="EnsemblBacteria" id="ABX03844">
        <property type="protein sequence ID" value="ABX03844"/>
        <property type="gene ID" value="Haur_1196"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1196"/>
    <dbReference type="HOGENOM" id="CLU_2479069_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1218-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="87" mass="9582" checksum="8796818C6058564D" modified="2008-01-15" version="1">MTTNNDLGVMAIVIDRIVMIMAVVSIMMIVMAMTTNAIFTNFTGGFNSPIIFAIDGISKCHKKLFNAHYGSPLNDLLSHYTKSGRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X8</accession>
    <name>A9B0X8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="4">IMP dehydrogenase</shortName>
            <shortName evidence="4">IMPD</shortName>
            <shortName evidence="4">IMPDH</shortName>
            <ecNumber evidence="4">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">guaB</name>
        <name evidence="12" type="ordered locus">Haur_1200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="4">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 9">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1200"/>
    <dbReference type="EnsemblBacteria" id="ABX03848">
        <property type="protein sequence ID" value="ABX03848"/>
        <property type="gene ID" value="Haur_1200"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1200"/>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_1_0_0"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="98"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="158"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="342"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="365"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="4">
        <location>
            <begin position="389"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="4 5">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="252"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <begin position="302"/>
            <end position="304"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="52605" checksum="AF37DA2BAD9B0787" modified="2008-01-15" version="1">MPIDWSAKFAFEGLTYDDVLLIPAYSDVLPSQIDVSTWLTREIRLNIPVVSSAMDTVTEDRMAIALAREGGLGIIHKNMAPAQQADLVRRVKRSESGMITDPITLRPEQTIGEAWELMSDYHISGVPITSAAGELVGILTNRDLRFETDPSRKISELMTSEELVTVPVGTTLEQAKQALHQHRIEKVLVVDEHGKLNGLITVKDIQKQIEHPNATKDAYGRLRVGAAVGASTSELERVRLLVEAGVDVIAVDTAHGHSKAVLDAIARIKQQYPELQIIGGNVSTGEGARALIEHGADAVKVGQGPGSICTTRVVSGAGMAQVTAVMECVKAAEEAGVPIIADGGIKYSGDVAKALAAGAHTVMLGGLLAGTDESPGEMILYQGRSFKSYRGMGSIGAMQQGSSDRYFQSNQPARKLVAEGIEGMVPYKGALADTIYQLVGGLRSGMGYVGAHNVDELRKNARFSRISPAGLAESHPHDVTITNEAPNYERRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y2</accession>
    <name>A9B0Y2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase/Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1204"/>
    <dbReference type="EnsemblBacteria" id="ABX03852">
        <property type="protein sequence ID" value="ABX03852"/>
        <property type="gene ID" value="Haur_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1204"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_4_2_0"/>
    <dbReference type="OMA" id="EQHFNDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1226-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735168" evidence="2">
        <location>
            <begin position="26"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36857" checksum="93154ECA15D7FD91" modified="2008-01-15" version="1">MHMQRLCYFLGLLGLSLSLFSCSRANRQAVAVSPNSTSQVAEPNSLGLPKGTLHEAELLVAGETRSFIYYLPAKLDPVGAPLVFMLHGGGGLGNSAMTLTTQERWNTLADQHGFIVAYPDGMNRRWNDCRSDWDNPSTSDDVQFISTLIDHFAQTYSIDQTRVYATGHSNGSMMSLRLALELPDRIAAVVGSAGYMAQNSQCKMLGTPAPLMLLAGTADPIMPYAGGLIDIPGDSQQGQVLSAEATIQMWLDMLSITNQPSISHLPDINPDDHSTVTINTYQDNLVRFYRIDGGGHTWPSLEEPARLQQRQNPHNRDFYAADAAWEFMQQHRLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B132</accession>
    <name>A9B132_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2672</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2672"/>
    <dbReference type="EnsemblBacteria" id="ABX05310">
        <property type="protein sequence ID" value="ABX05310"/>
        <property type="gene ID" value="Haur_2672"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2672"/>
    <dbReference type="eggNOG" id="COG4152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="HRMNEVE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2702-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="33426" checksum="5F51804930E145A5" modified="2008-01-15" version="1">MAMLNIVDVKKSFAGTEAVRGVSFNVEPGELFGVLGPNGAGKTTTIRMILDILRPDSGSIEVLGGAMDEAKKNRIGYLPEERGLYRNLKVLDCMVYLATLKGLERNEARKRASDYLERVELGHVAQKKVSELSKGMQQKVQFGTTILHEPDIVIIDEPFEALDPVNTRMVKDLLFDIRREGRAVLMCTHQMHLIEEMCDRIVMFNRGEIVLNGTLRDVRRRFAPNAVWVEGHGSFDNLPGIESVQTENGQVQLNLQAGTSPQSVFQALASRSDTTVDRFEVAIPSLDDIFVRVVNGERGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K8</accession>
    <name>A9B1K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1245"/>
    <dbReference type="EnsemblBacteria" id="ABX03893">
        <property type="protein sequence ID" value="ABX03893"/>
        <property type="gene ID" value="Haur_1245"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1245"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_0"/>
    <dbReference type="OMA" id="FPGRDWW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1267-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="82"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="31884" checksum="119D0D1886BDDDB2" modified="2008-01-15" version="1">MTSLPIKSTLKKPHQAGFGRYLVLAALIIAVLVVLLPFAIVVINAFKTPTDYASNGPLSWPSAWSIDGIVEFWQRVDYSQKLLNSLLISASVAVIGVLLSLLNAFALGIGRIKGRVWLLILFMVANTLPQESLVYPLYYLSKEFDLYNTRFVVILIFSVIQSAFGTYLLSSVFSTFPKEMLEAAMLDGCNKLQLLFKIIVPVSRPTLSVLFTFFFIWTWNEFFLPLILLISNDRQTVPIAVGVLQGQRNMEATLSSASALLGILPCFIFFLIFQRTLTKGIAAGSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S1</accession>
    <name>A9B1S1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2725"/>
    <dbReference type="EnsemblBacteria" id="ABX05363">
        <property type="protein sequence ID" value="ABX05363"/>
        <property type="gene ID" value="Haur_2725"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2725"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_0"/>
    <dbReference type="OMA" id="WQQSYGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2756-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="226" mass="25740" checksum="3656BF256EDCCE1F" modified="2008-01-15" version="1">MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAMDGYETCRRIREFSNVPILMLTANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRRIPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQLLILLADSVGQVVPHEKLLGSIWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Y1</accession>
    <name>A9B1Y1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="9">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">metG</name>
        <name evidence="13" type="ordered locus">Haur_2785</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2785"/>
    <dbReference type="EnsemblBacteria" id="ABX05423">
        <property type="protein sequence ID" value="ABX05423"/>
        <property type="gene ID" value="Haur_2785"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2785"/>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_1_2_0"/>
    <dbReference type="OMA" id="SDMHGTP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="11">
        <location>
            <begin position="5"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="12">
        <location>
            <begin position="412"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX05423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="574" mass="64849" checksum="9DA89C969545F766" modified="2008-01-15" version="1">MAKNILVAVAWPYASGARHLGHVAGFGVPSDVFARYQRLVGNNVLMVSGTDDHGTPITVRADREGKTPREVTDFYNAEIRNNLRDLGLSYDLFTRTSTENHYQITQAFFTRLQEKGYIFAQEMIGTYSEADKRFLPDRYVEGTCPHCGYTKARGDQCDNCGKQLDPVDLIEPRSTLSGATPVFKPTTHFFLNLPAFVERLREWIESQNHWRPNVKRFSLGLLDDVPARAITRDLTWGVPIPVEGDEFDSKRIYVWFDAVIGYLSAAVEWSIKVGRPEAWRDWWLNSDARHYYFMGKDNIVFHSVIWPAMLIGHGELELPYEVVSSEFLTLAGGEKISSSRAEGNSIPFVGEFLAQYDPDPLRYFLVIAGPETSDTEWSLGEFIRRNNEELVATWGNLVNRVLSITHKNFGHVPTPQALTAEDEAALATVRAAFETVGKELEQAHFKAGLIATMAAARSVNEYLASQEPWKVLKTDRERGGTILYVALQAINNLRTLFTPFLPFTSQKLHELLGNEGYLAGPLLFEERQESQHSHEVLTCEPSTWIGRWEWSDLPAGRELAAPSVLFKKLELPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B292</accession>
    <name>A9B292_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4812"/>
    <dbReference type="EnsemblBacteria" id="ABX07442">
        <property type="protein sequence ID" value="ABX07442"/>
        <property type="gene ID" value="Haur_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4812"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065333_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4871-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="39781" checksum="AE31544F33B9D018" modified="2008-01-15" version="1">MDQIGRRTVTSLSVGLVAIIILLVTIGQQPSAGQVANNTPNQAQAQVSGILFLRNPAQQAELWRSDANGQGQQLLVPQVSDYSLSPDGRKVAYATQAEAQPSRIEMFDLTQNQVITSTGSADWTGYTPNWSPADGVIVYERRTISTGGVGSPKLWLMQPDGTQVSPVVKGGDVVTFGAHWSNTGRLLGFTDPLRNELVLFDFSDVLRRIPFSGDFDWSPDDQRLVISVLRESQAGFRNELILFDLMTEQQTPLTSQTDTDDFTPVWSPDGTKIAFVRRTREVPRGEIWVVNADGSEPRAITAGGGYDNVDPQWTPDSQQLLWTRLTVGSANVPSAIWTVNLAENSEPRVLIENATQARWIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R5</accession>
    <name>A9B2R5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2878</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2878"/>
    <dbReference type="EnsemblBacteria" id="ABX05516">
        <property type="protein sequence ID" value="ABX05516"/>
        <property type="gene ID" value="Haur_2878"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2878"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1021886_0_0_0"/>
    <dbReference type="OMA" id="GAMTAFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2909-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="51"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="32507" checksum="907E92B1B4CE0A12" modified="2008-01-15" version="1">MSVILDKHTAVERQPNPRRGKGPSAFTIFWRSVIGRAYPRIIGTQRELSWLFFDIFLPFMATMSYVLVYEAIGAPASYKGLVLVGGAMTAFWLNVLWSMAMQLYWDKEQGNLQLYMLAPTSRMAILTGMALGGLFATTIRAAIILIGGSLIFGIRYQATNWFALVGIFFLSLIALYGMGMLLSSIFLVYGRGAWQMTAALQEPVFFVSGFHFPVKALGTVVATGASVVPLTLGLDAMRQLLFPEMMQQFQFLSVGTEAAILAGLALGFGLVARWALLRMERKSRQDGRLTERGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2T3</accession>
    <name>A9B2T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2896"/>
    <dbReference type="EnsemblBacteria" id="ABX05534">
        <property type="protein sequence ID" value="ABX05534"/>
        <property type="gene ID" value="Haur_2896"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2896"/>
    <dbReference type="HOGENOM" id="CLU_2034872_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2927-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731832" evidence="1">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="12601" checksum="65A8E5F0BD24DB14" modified="2008-01-15" version="1">MIKASRRMLGLLAATCALALAPLTPSAAAPNALDVSVFCENLGMRNNQGSFSCDAFASGGTGDYSYNWSAVQNATILENWGSYIYGSCAINQSARVNVVVTDNSGASVSKIGRVLCRKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W8</accession>
    <name>A9B2W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06031">
        <property type="protein sequence ID" value="ABX06031"/>
        <property type="gene ID" value="Haur_3395"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3395"/>
    <dbReference type="HOGENOM" id="CLU_1956590_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3432-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14268" checksum="77A36F621FEA269E" modified="2008-01-15" version="1">MTSRISTIIEQIAHGNLKTLRAEQIELHAAYLLVDQAIFMWVSLVKIAQVTVHKAFPTKQLLISSAALTMLMGLKSPILVEPAQNLLSAGLILWILYLFYSNAAEHPAPRPTWWVPRAGCMRASSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y6</accession>
    <name>A9B2Y6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3413"/>
    <dbReference type="EnsemblBacteria" id="ABX06049">
        <property type="protein sequence ID" value="ABX06049"/>
        <property type="gene ID" value="Haur_3413"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3413"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024566_5_0_0"/>
    <dbReference type="OMA" id="WYADDPE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3450-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="32687" checksum="FF661A2F6022AC5F" modified="2008-01-15" version="1">MTAAQQRMLAALTGLSVGEAYGQQLWQQVQTGLAVADQPSLLPAPWLWTDATLMACSLVDQLWHYGAVHSAALAADLALRYTPVRDYGTSMHQLLAKPRDGAAVMSDAQNLFDGQGSFGVGAAMRVAPLGLFLADAPLNEVAQQAQLSALTTHTHPEAVAGAVAVAVAGAILWRERDQPLRQPSAILAEIGQYVPSSSLEHRLALAAAMNDRQMWHHIALRLSNGYQHSAQATVPWCLWCAVHYRDDYAAAIEQVCAAGGNFTSMAAIVGGLLAGTLGRDCIPPPWLHAREPLPSWFLASLGLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B386</accession>
    <name>A9B386_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IstB domain protein ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1404"/>
    <dbReference type="EnsemblBacteria" id="ABX04049">
        <property type="protein sequence ID" value="ABX04049"/>
        <property type="gene ID" value="Haur_1404"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1404"/>
    <dbReference type="eggNOG" id="COG1484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_3_2_0"/>
    <dbReference type="OMA" id="ERIHMLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1425-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="110"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="29631" checksum="26DE8C6A06080E5F" modified="2008-01-15" version="1">MQRFDTSIQASVTPAPDMLPPVVPWEPNETCPCCKGAGYFVYDVAVDHHMFGKLQACGCLQQRQIERRRSELHAKSGLAPFRGKTFASFDRTIAGVDHAVGAAQAFADNPDGFLTLVGNPGCGKTHLAQAIGNALQARGFEVVWSTAPDALRLLRSTFDQTSNKPKNSFDEQFELFRKAPMLLLDDLGAENATDWGKETLFQLLNERYEYQRPTVITSNLHPNTAEANRRFGMRLCSRLLDAVQGQLVVVQAADYRRRDPMDRLGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3K5</accession>
    <name>A9B3K5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05577">
        <property type="protein sequence ID" value="ABX05577"/>
        <property type="gene ID" value="Haur_2939"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2939"/>
    <dbReference type="eggNOG" id="ENOG5033UD7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_815785_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2971-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="340" mass="37943" checksum="B36D8AF4723FC237" modified="2008-01-15" version="1">MSGSTIQFPQKFQGIFKRSQASFAPHLQVARQLLNSLNIPAPLQHVWDYVVVDNPQPSFILLPLLFLSLAEQLGGITPAHQRALPVIMLTMEAVAVMDDTVDISSRRSERATVPARFGVTQATPIATSLTATIAELAVEIDPRLVQPTMNFLRELGALQIWEVEHSYPEQAEWDEWMQQRYRQGQIATEFALNLALMYHRQAPFPATPAYFFAQIMQDVDDVVGLLEQRVQFGEGCDLQRGRVIAPLADACDNNIQLASLISQLWRKKQALLAESNQTTFQQLNQHVLEAGLATTLDRLTQIAIACEEQTPPALQAWMYDVICTFMARLSGVGLAQTQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B441</accession>
    <name>A9B441_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsI</name>
        <name evidence="6" type="ordered locus">Haur_4944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4944"/>
    <dbReference type="EnsemblBacteria" id="ABX07574">
        <property type="protein sequence ID" value="ABX07574"/>
        <property type="gene ID" value="Haur_4944"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4944"/>
    <dbReference type="eggNOG" id="COG0103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_2_1_0"/>
    <dbReference type="OMA" id="QWKINGR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14714" checksum="F40B7F3C512C25F7" modified="2008-01-15" version="1">MSEQRYFQGTGRRKTAVARVRLYPGTGEFVVNGRTSEEFFGGRALYQQLIRQPLLAANQLGSFNVLIKVRGGGDTGRAEAVRHGIARALVDADPAFKPIMRAAGLLTRDARKKERKKPGLVKARRAKQYTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B0</accession>
    <name>A9B4B0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sigA</name>
        <name evidence="10" type="ordered locus">Haur_0015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0015"/>
    <dbReference type="EnsemblBacteria" id="ABX02667">
        <property type="protein sequence ID" value="ABX02667"/>
        <property type="gene ID" value="Haur_0015"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0015"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_3_0"/>
    <dbReference type="OMA" id="ASHQMLR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="167"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="246"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="335"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="400" mass="45759" checksum="022B60A81E037D48" modified="2008-01-15" version="1">MALDDEILDSELAGDETDDFPALRTLSDLLATGKKRGYVTPGEIQQIIDSQRDEDKQLEEIRDTLQKANIRVEETGDDDDEITVSENPEADFSNEGISVNDTVRLYLREIGLVPLLKGEQEVELARAMEDGDKAQQELIENDHTLSDVERLALRRRIDRGEQAREHLTTANLRLVVSVAKKYIGRGLSLLDLIQEGNVGLIRAVEKFNYTKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINRMMRTARRLTQENGREPSDEELAQALDLTVEKVRSIRKTSMEPVSLETPVGQEEDSQLGDFLPDEKLEAPSDAASHQMLREQVAQVLDQLTEREKRVLKLRFGLEDGTQRTLEEVGKEFGVTRERIRQIEVKALRKLRHPRFGKKLRDYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I4</accession>
    <name>A9B4I4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1505"/>
    <dbReference type="EnsemblBacteria" id="ABX04149">
        <property type="protein sequence ID" value="ABX04149"/>
        <property type="gene ID" value="Haur_1505"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1505"/>
    <dbReference type="HOGENOM" id="CLU_3026102_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1527-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="55" mass="5899" checksum="CBD90231A1E1F9C1" modified="2008-01-15" version="1">MQIALDANGNTLLVGTIVDQAALYGLIKKIRDLGMQLISIMPVPPTTLESDSTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4K8</accession>
    <name>A9B4K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1529"/>
    <dbReference type="EnsemblBacteria" id="ABX04173">
        <property type="protein sequence ID" value="ABX04173"/>
        <property type="gene ID" value="Haur_1529"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1529"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_472321_0_0_0"/>
    <dbReference type="OMA" id="LNFYNVH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1553-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="2">
        <location>
            <begin position="48"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="1">
        <location>
            <begin position="351"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="577" mass="61850" checksum="A3F144AD15AD749B" modified="2008-01-15" version="1">MTTFDDYRSPDAPIAATTVAWNMYGAGVEHIGRNAQPETFAVTEPAADQLLVRVDAVGMCFSDVKLIQQGGRHPKLYNRDLATEPTRLGHEAALTVLKVGAHLQNQYQPGQRLAIQPDIYQDGMSTAYGYTIPGGLTQFHLIGAEVLNADDGAYVLPVGEGMGYAETALTEPWACVEGAYTQRRRLNPKEGGTLWIIGQTGDQRSYSFSSGFDAPARIILTDVPQQLQQQLQQTSKAQIIVRDGLSVDDYLELRNDLTSNQGFDDVVMLDPRSASQVSAAAGLVARRGTFNLVGQTALDGLPEIDVGRIHYDYIAYVGTNNSDISAAYGEARNRCDLQPNGVAVFVGAGGPMGQMHVQRAIELPNGPRTIIATDVNDDRLRALDRLFRGLAESRGKRLLLINPTVENSLHATVMLETDDLGADDVIVSVPSGPLMGDAATLMAPNGMLVLFAGVPNGTFAPLNLSNVYLANAQFTGTSGSRIIDQATVIQKTVAGELSPNRSVAAVGGIEAALDGVKAMMAGTYAGKVVIFPQLSGLPLTGIDELHKNFPEVAAKLGEGNVWNPEAEQALIETFWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B509</accession>
    <name>A9B509_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3094"/>
    <dbReference type="EnsemblBacteria" id="ABX05732">
        <property type="protein sequence ID" value="ABX05732"/>
        <property type="gene ID" value="Haur_3094"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3094"/>
    <dbReference type="HOGENOM" id="CLU_1914170_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3126-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14067" checksum="4F4FE69D959648B0" modified="2008-01-15" version="1">MRTFRMIWASAAGWMVDYFLTMLIVPLGYAALDISTISDIQLNNPLHIVVALILPALMTTIGGGVAGRLSLENPTPAGALVGGWGLLMLFDSPLEQNSFTLAMLITQCVATLGAALAANYIAKRTLQKSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B526</accession>
    <name>A9B526_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3527"/>
    <dbReference type="EnsemblBacteria" id="ABX06163">
        <property type="protein sequence ID" value="ABX06163"/>
        <property type="gene ID" value="Haur_3527"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3527"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3564-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="93"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="275"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="355"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="481"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="550"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="667" mass="75070" checksum="2B722235B4F30631" modified="2008-01-15" version="1">MAQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPLEQFHVADDRSGDDAYASEYQSHDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDANQVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMVFQFVLHPDGTSEFPYVSEGIRQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVRGASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPYYANAKAQELLGQHVMLPVSQQTETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFRYADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIAQELFDWRQRFDLIMSTVELVMYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCSTYAVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIEAQAAALRELSTPLIPINDRTVIMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGVPVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVSLGISLGDVVTLSNLQSGIERALNRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B539</accession>
    <name>A9B539_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3540"/>
    <dbReference type="EnsemblBacteria" id="ABX06176">
        <property type="protein sequence ID" value="ABX06176"/>
        <property type="gene ID" value="Haur_3540"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3540"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049009_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3577-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732467" evidence="1">
        <location>
            <begin position="24"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="36882" checksum="FCA5381BD3C3EA75" modified="2008-01-15" version="1">MLGLATATLAVAALVVQPRPTAAAEPIILETQCFDVPGIVDCLDDDFLSYWRNNGGLPVFGYPITEAADQYNVDSDDFYWTQWLERNRFELHPENAGTPYEVLLGLLGKERLSQLGREIEPREAGPVEGCLWFEQTGHNVCNQAGNLGFKSYWQSHGLKIEGLDTYARSLQLFGLPLTSAQTETNASGDTVITQWFERARLEWHPNNPDEFKVLLGLLGKEILDDVSEPLPPAEQCAQTPDPVSANIRPTKCPQVGTVVFFDFFGFQPNEEVVLWVVDPAGEVYEFDEGTTIGPSGSVENVEWPTAGSPTGLWLISLEGKTSGHVADIYFTVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F3</accession>
    <name>A9B5F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0126"/>
    <dbReference type="EnsemblBacteria" id="ABX02778">
        <property type="protein sequence ID" value="ABX02778"/>
        <property type="gene ID" value="Haur_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0126"/>
    <dbReference type="HOGENOM" id="CLU_2355866_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-129-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="11274" checksum="90A3F5F5CE028CBA" modified="2008-01-15" version="1">MQRWRHWLEWLVLGGLSVLIARLMLLLFAANPEQPFTQIVLWLSQGLVWPLAWLDQTQPTTGVRFERGTFLLIMFGLVGMSIWQLRQARRTNHGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J1</accession>
    <name>A9B5J1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0164"/>
    <dbReference type="EnsemblBacteria" id="ABX02816">
        <property type="protein sequence ID" value="ABX02816"/>
        <property type="gene ID" value="Haur_0164"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0164"/>
    <dbReference type="eggNOG" id="ENOG502ZHR3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1508617_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-167-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="20139" checksum="43BD712F3D0E12AA" modified="2008-01-15" version="1">MKRCEHRTNYDLREEALDPQLTDHLAECESCAQRARRAEAFDTVVRSAMITSVPDDLTAKLLALVPGLMPPMLVRSKHWKLQRRAFVGLSGFASILALGLLIYGVYLLANTVGVGDWLATASTWPGVAIDWLYRHIPSSRSFVAAMIAVRQPLQWMILLLLIWQVWERMPLPNNRQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5K2</accession>
    <name>A9B5K2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-superfamily hydrolase, subfamily IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1592"/>
    <dbReference type="EnsemblBacteria" id="ABX04235">
        <property type="protein sequence ID" value="ABX04235"/>
        <property type="gene ID" value="Haur_1592"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1592"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_1_2_0"/>
    <dbReference type="OMA" id="MDGVLIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1616-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="27754" checksum="42DE296FD4770C99" modified="2008-01-15" version="1">MLNLKQLKLVLLDMDGVLHRGGEILPGAAELTTVLDRLGLGYACLTNNSSQLPATFARHLQDLGVAIAPEHVITSSTATATLLRTRYPQGTRLLAIGMDGIQSSLFADRYFVSAETDVAAVVVGVDFNLTYARLKTATLALRAGAAFIATNSDRTFPAPEGLIPGAGSIVAALAAASDCTPEVIGKPEPAMFEAALQLFGVTAEQTLMVGDRLDTDIAGAQRVGIATAFVGSGVHSMQQAQAWQPAIDLVADDLAGILALLRAGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R8</accession>
    <name>A9B5R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1658"/>
    <dbReference type="EnsemblBacteria" id="ABX04301">
        <property type="protein sequence ID" value="ABX04301"/>
        <property type="gene ID" value="Haur_1658"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1658"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_0"/>
    <dbReference type="OMA" id="GALPHMY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1682-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="25509" checksum="D889CE64032BE95E" modified="2008-01-15" version="1">MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHCDVSHEADIQALVQFALDQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQKYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSKTGAIELASAGIRINAVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYIIDGGITSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U7</accession>
    <name>A9B5U7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3102"/>
    <dbReference type="EnsemblBacteria" id="ABX05740">
        <property type="protein sequence ID" value="ABX05740"/>
        <property type="gene ID" value="Haur_3102"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3102"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_269699_0_0_0"/>
    <dbReference type="OMA" id="HGERIWV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3134-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1211" mass="133736" checksum="FB6BD4257554DB48" modified="2008-01-15" version="1">MCMQSQKQAFEDSSAHFLREWLPRLATATSINGLHTNLSAALRQFRHNPHYHLIWLDLAETQPEIPLELMLSSNQQEQLEQGAILTITTADATQWTMLPLLHITLRGWLALPEATQNDQLLLPLALQTAASMCTITNNQQLVAELRELTQFNLISQRLNSSLELGPLIEAVYRGIQQMFGPQNLFVSLYDPESQLFQVAAHFYADGRSTTPNSQWTVAHGLTGVIIRRNEPIITDRYLETCAQYHVTPLFIDDDIPPLFWAGVPLRFGERVLGTLVIYTLEPEVRYNADTLRKLEMLAHRAADNFEQARLYERTTRQARQLELLNELGRTITSTLDFEAVPSLIMGRVQELLNVEEGSLLLLDEATNELVFRYSLSPVGQQLLGNRIPSNVGIAGLVLRTGESLIANRAGDHPAFYTGIDMLVGHETRDLLCVPLLGAGGVKGVIEILNHRNGLPFTAADRALLEAVADQAVIAIENSNLYTQTDQALTRRISELDQRNKQFQEIVQIGNALKAASNLGSVLPALAEAVQSATGFNQVTISLVQTTPGHKAIIKRVVSAGIDRQIFEAQASITIEPERVEALLKPQYRRGESTYYIDHRRNGDARLWPDPSNGVDVPELRTGMWHPNDSLFAVLRSTSGDLLGLLTVYAPKNGLQPTTDQIQMLEIFATQLAVALENNRLYERQRQTVEGLTALSALGMAINSTFSNAQSIWQFTVGGMVDWTGALGAGVLLSDPNDPTTLQPIVGLGIEHTPDEAIIQFAHKVLERDKPLLLGDRSKLPSVLRDLGGQALVMLPLLATHQTLGVIYLWYPETLPNREAQDLLSLFVGQAAVAVETRRLAEEVSNGRDRLASILASTEEGIILLSADLRVVEVNAAAQTMIGSNEVAELLGEPVDLLLTHWCAQWNKSEEAWSELTLAIYKVSRGRLAEARGQLELGGLRSQWLEWTTLPVQSAANQSPHPIIIVLRDITTEIEAENLRHDLTYMMIHDLRGPLSSVMTSLDMLAKKMVGDLSEGQDKIVKIALRSSARLLDMVNLLMDISKLEAGQMPITPITVAVDDVVRSVMQNYEPLLNERKVHVALNIAENTPKASVDIQTLERVVQNLLDNAIKFSPALSTITISANKVQANQLPSDHPTGQWILLGVRDAGPGIPAQYRERVFEKFAQVKQTGIKGTGLGLTYCRLAVETHGGRIWVANDDGPGALFLLTIPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W9</accession>
    <name>A9B5W9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3125"/>
    <dbReference type="EnsemblBacteria" id="ABX05762">
        <property type="protein sequence ID" value="ABX05762"/>
        <property type="gene ID" value="Haur_3125"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3125"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_8_2_0"/>
    <dbReference type="OMA" id="DPYNDFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3157-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="23075" checksum="0351BA021891FEC4" modified="2008-01-15" version="1">MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHAPISFAEGYREITSHPYGILKGVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFASTNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYNVITLTDCVAATSAEEQQGAISKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y2</accession>
    <name>A9B5Y2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3138"/>
    <dbReference type="EnsemblBacteria" id="ABX05775">
        <property type="protein sequence ID" value="ABX05775"/>
        <property type="gene ID" value="Haur_3138"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3138"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084744_0_0_0"/>
    <dbReference type="OMA" id="ADFLIAP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3170-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AhpC-TSA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="19905" checksum="4CA8116E2C19F458" modified="2008-01-15" version="1">MPRYQAGQTINPRNLTSIANQALSIPHPQQLTHLQFRRFAGCPMCNLHIRAFIQGHAALAKAGIQEIAVFHSSKTAMLASHAEAPFALVADPSKKLYAAFGVDSSIWAVLHPKSWLPMLKGLFKHGVGMPEKGQNPLGLPADFLIAPDGTIVACKYAVYGYDQWSLSEVLQLAQQYQQRSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B602</accession>
    <name>A9B602_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3158</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3158"/>
    <dbReference type="EnsemblBacteria" id="ABX05795">
        <property type="protein sequence ID" value="ABX05795"/>
        <property type="gene ID" value="Haur_3158"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3158"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="OMA" id="WWITADS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3190-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="649"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="792"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="800"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="814" mass="88674" checksum="680EC4266AF4AB25" modified="2008-01-15" version="1">MEMPALIGLLVDAVLAVSPAADRLTIEAAFGAMLAGKPTLLDDAPLSLLIDQSSAQSHATIVYAGQTIAVELAEPLDPLVVALAAVASLPLTTVPAPRADQPAASRLPFESSSTFVGREQELLALAAALSHAQPTIVLPAVATGLGGIGKTSLVTEFAYRYGSYFHGGVFWINCADPEQVENQIAACAEALAIDPTGLTLDAQVQHVLAAWQAPLPRLLIFDNCEDPVILERWMPTLGGCRVLVTARNQLATMSAIRLGVLAPAESRALLQQLCPRLTTAEAEAIAADLGHLPLALQLAGSYLNTYDQQSVAQYRQDLAVTHHSLKGGAGLPSPTRHEQDVEATFMLSLHQFDSANALEMLALDMLDGAAWCAPGVPIPRQLVLDFVPDETNAETALAALQLLEQRGLIDGSEALVVHRLLAQVVQVHRGSAQIRELAEYRINEHAVRISATRVPKQMLPLEPHLRHVTVRALAREDERVARLCNSLGYWEHLRGVYGEAERWYERGLAIMQKVLGPEHQNTARMMNNLAGIRLEQMRYAEAQALYEQVLGIWNVTFGPEHPDTARCMNNLASALGRQGQNAEALAMLEQALVVWEAALGPEHPDTAISINNLAVALEREGRYAESQVLQERALKVWKKTLGPEHPDTAASLNSLARLLEHQGKYSQALPFYQQALAIRETALGPEHPDVASSLNDLAGLLIEQKRYTDAQALYERALTIRELVFGPEHADTITAMANLAVALERRGQYREALELHAQALTISRKVFGDNHQTSQRIRASHARTVQAIQEAFDQSAAKRSSGKHTNDDHVKQWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B609</accession>
    <name>A9B609_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05802">
        <property type="protein sequence ID" value="ABX05802"/>
        <property type="gene ID" value="Haur_3165"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3165"/>
    <dbReference type="HOGENOM" id="CLU_1178918_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3197-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732503" evidence="1">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="25695" checksum="3BFED3749E6A0AFE" modified="2008-01-15" version="1">MKHYRIVVSFMVFGSLSVAACGRTSLPNTEPILRPQESRNQPITAVVVPTTTVDLTATILDQTAIVEGATKEAEYLAFEQYLADKTATSLAELPSTAPPWPTYEPVTPSPTREYRLFAHLECTTDEPGPAIFVTNCWHGVINNKDFVVYGHGIRNKAANNKIVGGSIGVVENDIPMGRYLLPSNTNALTIVQELSPYLVISVGDHYEVLFNLETYQWANLDGTPIPVTATPTSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B667</accession>
    <name>A9B667_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3642</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06278">
        <property type="protein sequence ID" value="ABX06278"/>
        <property type="gene ID" value="Haur_3642"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3642"/>
    <dbReference type="HOGENOM" id="CLU_579739_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3681-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="471" mass="52305" checksum="451313CEE8378304" modified="2008-01-15" version="1">MRRLIALGVLGLVLTSCGQTTKQPSAATPSPSQALLITPTLVEPPPTLTVLTSALPTHFDFVEAEPLFVEAIPPALEVQRVDADLRWQELPNAALLVLSQRFDDSVAALNYRDLGLFDPQGQLLFSPNHELEKLGWCSSEHSAYAPSAQWSDDGRWFLLGCQAELEQFRYAILDLAKNQWLLISAADSTGEQPSDVGVLLQHNQFWLTYNHAPSPATWVYQFEPATEHTTEISVFATMDSNVSSGLIDMQAQPDGRMLFHGWRAAARGLYLWQAGQLYRLQFEQPLLLDERLIWAENNEAALVYHTQSISSTLQQTYELKLDLKTQQVSLSNTSTAWIAPPATVARNGYSWNLRLDGWHFEHNQQAVAWLPNTEQLFTAFGDWRKTDGDAWICQVEQGVGANVLAIDATGQSRQFLHYPNVGFSYPDCVSESPSGLLAISLSNNRIVLVDAQGQELATIVGASRGWRPTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B6</accession>
    <name>A9B6B6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase domain protein FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3691"/>
    <dbReference type="EnsemblBacteria" id="ABX06327">
        <property type="protein sequence ID" value="ABX06327"/>
        <property type="gene ID" value="Haur_3691"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3691"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059021_1_4_0"/>
    <dbReference type="OMA" id="WFDRGYH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3733-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="12"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17118" checksum="94F323F0890F1425" modified="2008-01-15" version="1">MTLDPALFRQAMSRFASGVTVVTTIVDAKPYGLTVSAFASLSLDPALAIIAIDKRSPMHDLLLQAQAFAINILSNEQESLSRHFAGPQKHDWSEIAAAAGNRSIPLLDGALANMECGLFQAVDGGDHTIFIGQVEHVTLRDGLPLLYYRGAYHDLVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D8</accession>
    <name>A9B6D8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0189"/>
    <dbReference type="EnsemblBacteria" id="ABX02841">
        <property type="protein sequence ID" value="ABX02841"/>
        <property type="gene ID" value="Haur_0189"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0189"/>
    <dbReference type="eggNOG" id="ENOG50334A5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1249591_0_0_0"/>
    <dbReference type="OMA" id="FDQPYLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-192-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="221" mass="23986" checksum="463F4CF21046553A" modified="2008-01-15" version="1">MRRIDLLRNPKRLIPILIGSVAGIFVLIDRLFPGIDSINNGSQILLSWATVIAAFALIAGSINVIIHHIKRLASTDPKRWYSIALLLGVIIPPALAVYGYTTQGRANVLELGLFQDVIRWVYAPISISLLALLTFFALTAAIHAFGAGQREAIIVVSVALVFLLLQLPLLAGLPYLGETVGWIQRYIVMAGLRGLIFGSAIGAIVASIRILLGIDLPYLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K6</accession>
    <name>A9B6K6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sulfate ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0257</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0257"/>
    <dbReference type="EnsemblBacteria" id="ABX02909">
        <property type="protein sequence ID" value="ABX02909"/>
        <property type="gene ID" value="Haur_0257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0257"/>
    <dbReference type="eggNOG" id="COG4208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_0_0"/>
    <dbReference type="OMA" id="NEYNFVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-260-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
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        <source>
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            <dbReference type="ARBA" id="ARBA00025323"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX02909.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="29444" checksum="940C2B8BA0C9DFFA" modified="2008-01-15" version="1">MNWRKWLLISIVVGYMGILIIAPLGAIVFGAFREGAPAVLEALQHPHVLRSFGLTLIICLVVVSIHGIFGTLVAWVLVRHQFVGKALVNRLLDLPFAMSPVIVGFTLIVLFGRNGVLKPLTEALDWQIAFALPGMILATLFVTLPFMVRELMPVLEAFGRKQEEAAATLGASGWQTFRLVTFPALRWAFLYGLGLTCARALGEFGAVLVISGGIQGRTETATVYIFRALDDRQYAGAYSAALLLGAISLVLVLVIDVFHRRSQKSIEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
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    <name>A9B6N3_HERA2</name>
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        <submittedName>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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    </dbReference>
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        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="176" mass="19670" checksum="A815C4BF4A5AA298" modified="2008-01-15" version="1">MTTRSILVTYASRGGSTMGVAKAIATVLTEQRLPVTLLPMQQVKHLNSYQAVVAGSPIHKNRWLPEALAFVKEHQIGLRTKPFAAFLTCLALAMTNQPAKTLNDVAQWLQPVRHFVQPCSEGLFAGVLDLSKISLGYRLLFRGAMTVRRWREGDYRNWHAIEAWAATLPTKFSSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B718</accession>
    <name>A9B718_HERA2</name>
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        <submittedName>
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    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
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                <person name="Woyke T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3249"/>
    <dbReference type="HOGENOM" id="CLU_1935153_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3284-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732556" evidence="1">
        <location>
            <begin position="22"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14582" checksum="1C1E8FADB787CDA8" modified="2008-01-15" version="1">MRFVRLWWLFSLLLISLAGCGGDDVNKVHIRIRNDSEVDIENFWLGAGGVGQSTTPYGPIDSGHITEYQAHEPVLANYRKMNFVTVDGKQYLDVIYPEKHVGTPELAPGHYTFSYAIVGDKPVLTLTKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B753</accession>
    <name>A9B753_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil-DNA glycosylase superfamily</fullName>
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    <organism evidence="2 3">
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3700"/>
    <dbReference type="EnsemblBacteria" id="ABX06336">
        <property type="protein sequence ID" value="ABX06336"/>
        <property type="gene ID" value="Haur_3700"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3700"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044815_4_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3742-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="26"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="21585" checksum="C13348DF6352406B" modified="2008-01-15" version="1">MDQPFPLATACFKCWRRVQERNCIVHGYGDANAKVMFVGEVPESLGANQTGVPWTRTIAGQRLQVLLRALRLRTASDPEHEEPRLVGAYLTYLVRCSTHADSPPTMVETSNCVAYLWRELVLVNPRIIVTVGEAPTRLMCAKLFGHVPGNVESMHAQPLPVDQRILLPMIDLETITKEEAHVFARVLSALLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B766</accession>
    <name>A9B766_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3713"/>
    <dbReference type="EnsemblBacteria" id="ABX06349">
        <property type="protein sequence ID" value="ABX06349"/>
        <property type="gene ID" value="Haur_3713"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3713"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015805_4_5_0"/>
    <dbReference type="OMA" id="YDYHFSP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3755-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="115"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="210"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="295"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="397" mass="43998" checksum="795F8AE25F4FB659" modified="2008-01-15" version="1">MTVDTESMDAVQDWTTLLAEYDYQRPERGQLREGIVMRVEDSQILVDIGAKHEGVIPNQDLRRLPPELVSGIKNGDTLQVYVMEPESKEGELVLSLNMVQVERDWQEAQTMLENGQIIEAGVVGYNKGGLLVQVGRVRGFVPASQVVNLHSRTGTEGQQSAMTKMVGQNIPLKVIEVDRDRNRLVLSERAAMQRWRQSQKERLLETLEPGAVVTGRVNQLTPFGAFIDLGGADGLAHISELSWQRVNHPREVLQPGQEVQVYVLEVDRDRERIGLSLRRLQPDPWATIDQRYDLGQLIVGEVTNIAPFGVFVRVEEGVEGLIHASELTENGQSPDSLQQGQQVQVKVISLDRQRQRLGLSLRRVDGEGEAAEAPAAPVAEVVAEAATEATTEEEVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D2</accession>
    <name>A9B7D2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3779"/>
    <dbReference type="EnsemblBacteria" id="ABX06415">
        <property type="protein sequence ID" value="ABX06415"/>
        <property type="gene ID" value="Haur_3779"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3779"/>
    <dbReference type="HOGENOM" id="CLU_2000768_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3821-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="14068" checksum="0D2AFDE63EE9DD56" modified="2008-01-15" version="1">MTTALKAAFGQFFDCQDVNFLDELLAQPGRGTMPWQYVTPWEIRYLVELDAQGCSLEVYAVNRFTNDQHLKIDSAGVISHFASPVGYYAYDPALEGDREAQQQAMYTYNQAIYAELRTKGLIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J6</accession>
    <name>A9B7J6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0317"/>
    <dbReference type="EnsemblBacteria" id="ABX02969">
        <property type="protein sequence ID" value="ABX02969"/>
        <property type="gene ID" value="Haur_0317"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0317"/>
    <dbReference type="HOGENOM" id="CLU_1064654_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-320-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="27675" checksum="73A6FAE0253C5B2B" modified="2008-01-15" version="1">MSAVVELSRAEIVTICAVVSAASIMGVAPAQNPAEHAQLLQLGEAALRQRQLAQSDQDGMLMIARDPLALVATCAYPQRSLIIHHVQHNGSVLQAFGHKHADSVVFHEVLNSDMQRLQAFGSLAQLANYSLDWCGYAGSAELSVRWHIQSTVLAEARSLVEQSEEQAALRALGNSGVSAEAAIRLIELLSQPHTTTIFNAVVYQGQQVLSREYSLLQAGQHTLLMTQTNIEQDLYQLETTSRERLANLLIQSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S7</accession>
    <name>A9B7S7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
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    </reference>
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        <property type="gene ID" value="Haur_1812"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1812"/>
    <dbReference type="HOGENOM" id="CLU_1747134_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1840-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="17132" checksum="49E747C320DF554E" modified="2008-01-15" version="1">MVKFCAGLKMSAYFVISAYNPQASIDDQIDASSLADQLQINWVDYRHALINDWPAISFNHQPDWALEWMLEPAGMLGRLWHAGHSLEHQVAGSLTAAFIAWHRKYIDLRYPLYLFRPPQRVCLELVGSTSLTTIQTWLDQSLDHYRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
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                <person name="Pitluck S."/>
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                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
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                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1850"/>
    <dbReference type="EnsemblBacteria" id="ABX04493">
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        <property type="gene ID" value="Haur_1850"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1850"/>
    <dbReference type="eggNOG" id="COG3881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132076_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1879-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
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    </dbReference>
    <dbReference type="Pfam" id="PF05239">
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="89"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="17064" checksum="15458FEA98DEFBF0" modified="2008-01-15" version="1">MTTINSLFGKPIIAQSTGERVATVQDVVLDLPPTRVVALLTDRGGLLRSAHSIRWEQVISIGDVVVVGGETTPTSVNEDPELTALIKQAHQITGTTVITVDGTQLGTIADITIDERGQILGYELKQGLLQDLRGRTMLPIEQIRSFGNDALIVEQPAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B852</accession>
    <name>A9B852_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
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    <gene>
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    <organism evidence="7 8">
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3349"/>
    <dbReference type="EnsemblBacteria" id="ABX05985">
        <property type="protein sequence ID" value="ABX05985"/>
        <property type="gene ID" value="Haur_3349"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3349"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048252_1_0_0"/>
    <dbReference type="OMA" id="EDARVCK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3386-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="185"/>
        </location>
    </feature>
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    <feature type="domain" description="MFS" evidence="6">
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            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="48541" checksum="56C580E7EBCC817E" modified="2008-01-15" version="1">MQWKLALHRPIAPRASNEETLRRNMRLGVANGVLFILADAFSDANLVLTVFVRELGAAPWVVGLLPSLKSGGWLLPQLLSAGRLQGMTYKLPVYRQVGIVRFFIWLAMVLVVWNATSLPVWVLLPLFLLGYALYNFTGGSGSVAFQEVVAKTIPARQRGKFFGARNLIGGLLSFALVSPLVGWLLSRSSPLLFPHNYGVLLFISFVLIGFGIISFSLFAEPPTTNPPAAISTKQMFAKIPVLLKSDRNFRQYVLSRMVTRLGGLADPFYILYAREVLNVPPRMIGVYLAVRVFSAALSNLFWSRVGDQRGNRLLIVLTGALIITVPTWALLVMPFASILGPEALGWFFGVIFLLIGLSVDGSNTASLTYVMELAPAEQRPVYVGVCNTLMGIATFFPVLGGVLLAQFGYLPLFWISAASAFIGLLLSRRLPEPRIHEERRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B897</accession>
    <name>A9B897_HERA2</name>
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        <submittedName>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3814"/>
    <dbReference type="EnsemblBacteria" id="ABX06450">
        <property type="protein sequence ID" value="ABX06450"/>
        <property type="gene ID" value="Haur_3814"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3814"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_1_0_0"/>
    <dbReference type="OMA" id="MWAPVTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3856-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="223"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="579" mass="63211" checksum="DFC005A343153E32" modified="2008-01-15" version="1">MQRFLKSLAGLIAVGLIIYGMVPWSKEEHWLPCLWIATILGGFAIWPIRTQRATGIYTATQNLALFMIIGFTMLTLQLLRTQVIRADEIYNRVVAEDDGNIISNIRLVRSTNRIKRGAIFDSQGVTLAENVIVSDNRSYRTYPIANQYDMRAFGHTLGYVSSIYGLYGLESSYNEYLAGGKGNSWQNLQNQLFSRPREGNNVQLTINAQLQDRAFKALDGRVGSVVVIDVKTGAIRAMVSTPSFDPSQLTLRLDAEDYSAESDRVVNYWNSLISDESRPLVFRSTQGQYPPGSTFKTVTAIGVLNNPEVGKPEDITCPNELFPQEGVSVPVVNAVDDEAGYIAQKFGEKFGLDGVYAFSCNTAFAQYGIRLQDDGRNLLEDQARRFHIYPADELPDTGDLTDLPSAPSQLYGGEDGDEWWSQPVAIADTAYGQGRLLVTPLEMAMITQAIGNNGDMMKPYLVERVTTPQGGELYQARPRKIGDPMSVEVSQRIRISMKAVVEQGWSGATVAGVPGYSVGGKSGTAENPLGAPHAWFISLAPLDDPKYAVAVMVENGGEGTSVGGSLAGIVMSAALEINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D2</accession>
    <name>A9B8D2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3849"/>
    <dbReference type="EnsemblBacteria" id="ABX06485">
        <property type="protein sequence ID" value="ABX06485"/>
        <property type="gene ID" value="Haur_3849"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3849"/>
    <dbReference type="eggNOG" id="COG4485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008305_1_0_0"/>
    <dbReference type="OMA" id="MPTYQLG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3892-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09586">
        <property type="entry name" value="YfhO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="786"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="815" mass="90713" checksum="FC1F630BDF882B89" modified="2008-01-15" version="1">MSAMQPSLFLRQWQRWWPYLSITFVALLLLWRVVLGNIFLPLDIVAHLHPWRFSYERVAVNNPINSDLVTQIYPRRLVTNQILEQGALPLWNPTILTGTPLLADGQLAFFYPLSWLFVLLPVGYAFGIYTLLNVWLAGIGTFKFAQRMQLEPMPATLAAVGYMLSGFLLNWLHFPEFSAACAMLPWCFWAVLRACQSQRWHDWLLASLVLALPLVSQIQLAFYVYVGVGCLLLAQLLALPTWRLRFQQIGQFSSAIGLALGLSAVQLLPQIALSAQGQRLDIGSGLGSASSIMVWLLRLALPIVDGAARETASAWQPHLLQGIQPYAGIVSLALAGLAIWRSKQPGVRLFACLALGSFAVAIGTPLLQLLLWLVPPYRQFADHQRWFSLWGFAIALLAGFGLQRLQQPSNKPNRALWVQRGLLLLGLIGVAGWALQHIALFTVDSRYAQYSTMLRLALNPTSLAILGLSGLALVGLLIKRIPRRWSNLAVLLILLGDLLWYGGSYNTSIDPAIFQPTADQQASLAAEPALQDPAILYPPTRQINFLLSQPGVFRVFGADYQAMPTNVFSAFGLEDIRGYQSLYLAQYNRLTRLMDGKDYHKLGEGGNSLHAYFTMAYNQRRLLNMLNVEYLIFTPNSPNPELYQPLELVQRNDEGTIYRNPEVLPRAWMVYQTEVISDELAQLDRLAANDFDPAKQAIVAEPIPALGQAPSQTLTPTVSYEPNRALVQVETSAAGLLVLADAYTNDWQVSVDGQTAQLYRTNYALRGVWVDAGQHTVEFSYRPKSLIVGGWVSGLSLALILLGLALSWYKTRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N1</accession>
    <name>A9B8N1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07695">
        <property type="protein sequence ID" value="ABX07695"/>
        <property type="gene ID" value="Haur_5067"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5067"/>
    <dbReference type="HOGENOM" id="CLU_1822678_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5129-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15868" checksum="3E94BADB06627316" modified="2008-01-15" version="1">MVINPAPPWVGPVRVLRTARPRQTVERVLAVIPATQWLDRAVFWLMYDTQLRVLPLCRLTMADLDLAGPLPLVRCGERWRLVTEAPTVTALATYLSLRSPTASCFAAPTGLPLDLAYLDQHWRRYCQRAGVTCTLRELRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P1</accession>
    <name>A9B8P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRISPR-associated autoregulator, DevR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07705">
        <property type="protein sequence ID" value="ABX07705"/>
        <property type="gene ID" value="Haur_5077"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5077"/>
    <dbReference type="HOGENOM" id="CLU_068035_0_0_0"/>
    <dbReference type="OMA" id="HEGDPVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013414">
        <property type="entry name" value="Cas7/Cst2/DevR_sub_I-B/Tneap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010154">
        <property type="entry name" value="CRISPR-assoc_Cas7/Cst2/DevR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01905">
        <property type="entry name" value="DevR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02585">
        <property type="entry name" value="cas_Cst2_DevR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01875">
        <property type="entry name" value="cas_MJ0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="40355" checksum="E481C824AC0AE247" modified="2008-01-15" version="1">MAFVTGLLLIDASASALNNLGSIAGEREENTVGVKHIRVYGDGDYPYASAQAFRYWLRTTLETRFPAWVASPMYREEKIAYTDANPMQWWDDDLFGYMRAPSKKESAKAKREADPTLAQATETTDTITRVSPFRVGTLVSMNPVKIVSDFGTMSRHEGNPVPHEHQFYRATLKGLWSLDLRAAGTFSYRNKTGFRNLDSVREQLAKQQKLEHLEHAKSYRLPLEVRQQRVKTLFEGMAHLEGGAKQTLHYTDVAPVLTIFAVTKGGNHIFNHVVTTTDRGKPTINTAALDEALRVFADELLSPVYVGWVRGYNDQERQAFEEYLANSPAPIQLSHPREAFLNFAESILAAENHQWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W5</accession>
    <name>A9B8W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07779">
        <property type="protein sequence ID" value="ABX07779"/>
        <property type="gene ID" value="Haur_5151"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5151"/>
    <dbReference type="HOGENOM" id="CLU_062619_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5213-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="42381" checksum="472D87041D53EA5A" modified="2008-01-15" version="1">MYTIYCDESGFTGNNLSSDPQPFFIYASVNLDPAEASALVHEIRNSAKRFNKELKGSQLIRTCPSLVNTLFQSLQGRVSVLIVDKIYALTAKFFEFMIAPILHPLMHFLQASSFHHFVITTLYAYFKTNEQTANHFLRTFEACMREYNPDRLLALLDHGSETDETSEMLAGIRRLCHTYQHQIREALADIQNLGGVRKWILDISMPSLASSLMYWGKDGMPLRVYCDYNKALQEQYDLINFMTDCSKGTSIILDGVSFPLYSLVEPIHLVDSKQEPGVQLADIVASAFGAASRSGEGAWGDAFLHQHAALLHPACMMVNVEHMDLSLLPAYTNRRIFDELIRRVATDNDLFADLEFVITQAHADFPAWHALLNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B905</accession>
    <name>A9B905_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07819">
        <property type="protein sequence ID" value="ABX07819"/>
        <property type="gene ID" value="Haur_5192"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5192"/>
    <dbReference type="HOGENOM" id="CLU_075523_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5254-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="108"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="33580" checksum="CF3B1126356FF7D5" modified="2008-01-15" version="1">MIKRSSFFVSGFLLVLVFASSFGIRSAAARTWAQVNDGDSGVNVYTVQALLKQRGYSLDVDGDFGDQTLATVKSFQGSKGLTKDGIVGPNTWEKLVIETNQGDVNVVVKALQKQLNKHGASLTVDGDFGAATLTAVKSFQGRKGLTQDGSVGPNTWAALTGNASSDGGSGGGSTRAELADTILDSSRITLATVHVSGVNDSATAKQNIIDTANGRAARRSSYGNAPGGSVTLNTSMLKGMLTIARSWRYSVSEIAGGSHSATSRHYAGVAFDVNIINGTHVSASHPNQRAFQQKCRDLGATEVLGPGDAGHSGHIHCAWPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B910</accession>
    <name>A9B910_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07824">
        <property type="protein sequence ID" value="ABX07824"/>
        <property type="gene ID" value="Haur_5197"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5197"/>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="RDYITKP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="15170" checksum="439AC6061D0CB9E3" modified="2008-01-15" version="1">MTDALHILLVEDQAMNRDMLTRRFERHGYTVSLALNGAEAVVMAQAVMPDVIVMDMSLPVMDGWSATQRLKAIPIVQDIPIIAVTAYAMTGDRERCFAVGCSEYEAKPIQFGRLVEKIERWGGVRRSHMHREHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B911</accession>
    <name>A9B911_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5198</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07825">
        <property type="protein sequence ID" value="ABX07825"/>
        <property type="gene ID" value="Haur_5198"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5198"/>
    <dbReference type="HOGENOM" id="CLU_026775_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5260-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="182"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="256"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="309"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="387"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="436"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="579"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="694" mass="77660" checksum="BA640A41B7E2F726" modified="2008-01-15" version="1">MEVAPIPSDESARIQALHGLGILDTPPDPRFDRLTRLAQRLFHVPIVLISLVDTNRQWFKSCIGLDVQQSSREISFCAHAILQPDRPLIILDTWCDTRFADNPVVSGTPHIRFYAGHVLHAPSGAAVGTLCLLDTVVHSVFSDDDQEILADLAMLVERELAANTMHELLQTQHRLMTDFQESELRFRQMAETIDAVFWMSDSTRQQLLYISPAYERIWGYSCASLYADLQSWVTTIHPDDRASVTASMSKQAHTLRALEYRIIRSDGAERWIYDQSYPIYNDSDQVIRLVGLARDITQRKQQDLRVVQLTEQLTSLMQSLPGVVYRCSPDINWGVTILSDGIETLTGYPASDFLHNTIRPFVSCIDPLDRVRVEETMTAAIIAQQPYSVDYRIIHRDGEVCWVTNRGRAVYDDAGRVRWCDGVIIDVNARAAIEADHRRFVQLADMLPEFVGMATLDGQPIYINPAGRALIGMRPEEPLARQPLTALHPSWVQELLQTTALPTALAEGYWSGETALVTADGNEIPIDQMILCHRDAADQPTHFSTIARDLTHERQAAATRQALQAEILQIHTRTIMELSTPLIHITDTTILMPLIGAIDTIRAQRILESLLQGVSQQRASRAIVDLTGVPALDPHVAAIFIQAADAVRLLGAEVIVTGIRPEIAQTIVTMGVDLRRIRTYSDLHQGISYAMQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B914</accession>
    <name>A9B914_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NMT1/THI5 like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07828">
        <property type="protein sequence ID" value="ABX07828"/>
        <property type="gene ID" value="Haur_5201"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5201"/>
    <dbReference type="HOGENOM" id="CLU_028871_1_3_0"/>
    <dbReference type="OMA" id="AMQGYVT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5263-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735388" evidence="1">
        <location>
            <begin position="34"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="57"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="37439" checksum="799FF3ACCB921C98" modified="2008-01-15" version="1">MGIPRLALRAIGVRCFRSMRLLMLVFLTACSTAQPSPTPAPMDTVTIQLNWVNDYSSAGFFAAEKNGRFADQRVQVTLREGGFDANGYIDGTEQVSSGAADFGVASADSIIQARAQGKPIVGIAVLAQDSPLAILSLPQTAIRDPHDLVGKKVLVAEGGATQLYTTLLASQQIALTQAPPIPRTDSGIDQLIAGKIDALVAWNVNEAIELSELGYPPSVMLFSDYGINSYELVLITTERMVTENPDLVTRVLKATLQGWKDVILSPAQAIGYVKDYAPTVDRDGQMRRLSAFVELLQPTNTKLGDMLPDRWAFTHQMLQTQGALTQPIELGRAYSTMFLDVLPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B920</accession>
    <name>A9B920_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07834">
        <property type="protein sequence ID" value="ABX07834"/>
        <property type="gene ID" value="Haur_5207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5207"/>
    <dbReference type="HOGENOM" id="CLU_420216_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5269-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="671" mass="73814" checksum="39020316144ECEE5" modified="2008-01-15" version="1">MELPALTAVLVDAILAQCPQYDRVSVTVALESVFAGHPTLLGGNSISMLFGQNNDFTNATVTIGDVHAGNQVQVTLPQPIDLLPAALAALASIPLTDVPAPRSDLPQASRLPFESSPHFVGRETELKALAQAIGTTQPAVVMPAVATGLGGIGKTSLVTEFAYRYGWYFHGGVFWLNCADPNQVASQIAACVVGLKIDTTGLSLDEQVQRVLHAWQSPMPRLLIFDNCEDRAILDQWKPTVGGCRVLVTTRSDQWPTLTQIRLGLLSPAESHLLLQQLCARLTDAEADAIAEDLGYLPLALHLAGSYLATYDHHTVEQYRKDLTIAHRSLKGRGALPSLTRHELDVEATFMLSFNQLNPTNALDALALGMLDGAAWCAPGVPIPRDLVLAFVPEGVDADDALRRLQQLGLLDGADAVVLHRLIAHHVHDRLGDRRNAVRVIARWESQLAQRHGQAYFVLLRAALSHLRHLSTVMQGWGDPWVAICARHMAEYADAMNDDALAEEWYRQCLQAEHRAFGAVHGQVAATMNDLAEICVRQGKRQAALAYGQQAYQINRQLFGDQHETTAFYALRVGYFLRQHGLEQQAQAWYAQTLTILSQDDRAEERDVGLILEATLALVTLLQHTGQADTARQVYDRSMQILQPYAITEEMDAYWDGWQALQETMQSHGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B923</accession>
    <name>A9B923_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07837">
        <property type="protein sequence ID" value="ABX07837"/>
        <property type="gene ID" value="Haur_5210"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5210"/>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5272-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1447" mass="161423" checksum="273F4B4F1DA75846" modified="2008-01-15" version="1">MSQQPTAAYHRESERLLHLRHTGFVGRVAELADLQSLIDDLRPTGGYVVVTGDAGVGKSSLLAHAIIQAGIDQTPYHFIALTPGRAYQVDLLRHVIGQLVRKYPEAEAAFSAETYPALRLTFLRIVHDLAAQGVQETIYLDGLDQLQPDLDGLRDITFLPLQLPPGIVIVLGSRPDEALDRLGLDHGVVYAVPPLREADVLQRWQQVQPMLTPASVQPLARSVAGNALLVALAATLLGHAAPTVVPPWLAEASRDPSTLFRVSLDRIKHHDPIPWQRIIRPLLAVLVVTQEPLLPSSIAALIEQPVEQVQAVLGLVSEWVSVAADQRLALRHLMFYAYLAQHEFAAADVRVWHQRLATWCGIGLATIWEESGDPAEQARRWYARHHYVTHLALAEHWATLWQVIDAGTYGAHKVRFDPTRRLYGLDMDRARESVIAAGVGAAIDEQLAELPRLWRYSLLRTSLTADADGWLDDMFVIVAASGRLSEAEAQIALCSDPKRQVQLWSRILPYAELERRVALIQQMELVARNLRDADDRDRALGTVGMAYIDHGMFAVGYPLIRALAHKRDSRLYAAVVDRVDHGDSAHAQEVMAAIQTPTYQVQSALLIAKALLTGGAYEEAHALLMQIRPMARDGDLNTLLCLLADIQWAWGNLSQSQLLLAEAEGLIPSIAHWEHPARFRMILDGYLRHGDRVNALRCTQQGTDDSVRYEIVKLYLTHADAVTASQVAPMIAHDGYRDGAYKALILWYCQQQDLTTAHALLALIVEDQQHIEGAYVVAKAYAERQQFDAMDACLTMALDDDLGELNFFDFDCVFDIVELYARFGFHARACAILARVFPLIRELPRDWPEELPEWIRFAEITNRYAYAAFYDDLVRAVFIPKEPHSYATAVGTMAQGYAMHGDFTRAEQLASALTSPDMAITTLHALARIAQAAQRPPLAAHYLSAAHARLNTIADATAQIAWCGRLATTAWTMGLTDAARMLIDDGRQRWAQLPMHQQGVSSQRLVEGYQGQENLGEALAITQLMKDSPYYQQLIETLIAGCIKAQDLDQAYAILKQSHIAVPQYVAALCTIAITAREQGNMALAAHTCAEALLACDRYPVRRERLNFVKDLAISQLTHGSDACLPQLLAMLRSNDPCWDLPADVAMRCAIAAVYADQGDRASFAEWLGAAYDGTHHVLQSEDASRWVSIAYETLAKTYLAYADEAAIQAFLADFAAVVPRCVERGDASVAMKVLSQTYAHYAIQYQPSWREKAYQVARAIPDLWEGENTLAVVATAYVRVHDHAGVNMIIHEMRQRKFTRHEAMIQQHHNLCTIALAYAEQGDHAHAAALIAPLAPSSHRDRVLKVLIEDHRQADQWDAVYQLVDTYYDRTERVAVVQQIITAYRERQRIRESIALVHTTWRRCNHADELWSMSASILPFLLNDPSLGLALLDAVPWVEQQLRRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A7</accession>
    <name>A9B9A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07921">
        <property type="protein sequence ID" value="ABX07921"/>
        <property type="gene ID" value="Haur_5294"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5294"/>
    <dbReference type="HOGENOM" id="CLU_1123339_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5356-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="27882" checksum="E46277373A71992A" modified="2008-01-15" version="1">MSKRQVIVNQHIRIIPLRTITIACRWCGSEATIQSYPGRTPTLCSPECAEAARKDHDRQRRAAERANKPAPAPARGRKPKPRPTRFVLWPSQVDRSLDRSLDSQLKAMQTKANGRQLVATLDALLLEYLAVNVRWVILECIVREPQKLAERTEVALSIDDPRLDYRQWQREVELMRSELAGNGRLNQPQRDQLWALARTIETKVVGRHGLSQDFEDALTGSQRATAERALVVALVRLEGLLAGAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU91</accession>
    <name>A9AU91_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0359</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0359"/>
    <dbReference type="EnsemblBacteria" id="ABX03010">
        <property type="protein sequence ID" value="ABX03010"/>
        <property type="gene ID" value="Haur_0359"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0359"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_5_1_0"/>
    <dbReference type="OMA" id="GVMTIMN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-362-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="6">
        <location>
            <begin position="24"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="7">
        <location>
            <begin position="415"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="526" mass="58505" checksum="B5B81C0C998E3954" modified="2008-01-15" version="1">MNPQLQWNAAWRETTWQVLDQAWDVIIIGGGITGAGLVREATRSGLKALLLEARDFAWGTSSRSSKLVHGGLRYLAQGQVRVTYDSVVEREQLLNEAPGLVAPLGFLIGLPQGKPIKRWVYQAGLLAYDALARRREQHYLSMANLRLQAPYLADANLAAGLRYSDAQTDDARLVLRILREATAAGASVLNYAAVEQLVRANEQVVGVVVRDQLSQRQQTLTAKAIVNATGAWVDQLRQQIQAPAKMRPLRGSHLVFSQAQLPLAQAINLEHPRDQRPVFFVPWEGVSIVGTTDLDHEQDLWQEPSISPAEVAYLLEAAQAAFPSLDLSLSDVISTWSGVRPVVDTGASDPSKESRDYVLWQEQGLLTVTGGKLTTFRLIALEALKLLRQRLPQIKRWPNAPRLNPAPSSLAGTLAPRIKQRLLGRYAAEAPLMLQELPNHEFCSIADLPSLWAEIRWAARYEAVTNLGDLLLRRSRLGLLLPHGAAEYQAQIQAICTEELGWDAQHWQTEWQQYQQLIAQHYSLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD4</accession>
    <name>A9AUD4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0402"/>
    <dbReference type="EnsemblBacteria" id="ABX03053">
        <property type="protein sequence ID" value="ABX03053"/>
        <property type="gene ID" value="Haur_0402"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0402"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591564_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-405-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039059">
        <property type="entry name" value="MVP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021870">
        <property type="entry name" value="MVP_shoulder"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14165">
        <property type="entry name" value="PTHR14165"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11978">
        <property type="entry name" value="MVP_shoulder"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MVP_shoulder" evidence="2">
        <location>
            <begin position="235"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="462" mass="53224" checksum="4BC8938F24CD45EC" modified="2008-01-15" version="1">MIIPWIYYIQADEQLLVESLSRRWTVNGPRRYTARPFERITRRSGLVLGPTEYVYVTDSLTGQERLERGPQLFFPTAYEEIGTTQQALPLKKNQYVRILDRSTGQLRVERGEQSIYLQPNESQIGNIEAGYNIDEHHAVLVRSTTDGQLNLITTPQVFIPTAEQEVIEHRQRILLENHEVVVIKDRDGRYQFRRGSQRDRSFFLEPYTDLVTFRWSSGLHKDKRNLVITHLDIRPKFMWYAFEARTQDNVEIMIDITFFWQLADVEAMIVSTDDAPGDICAHARSAIIQAVSQTSLERFLANFNSIVRDAVIVPEDGFYAERGVKLHSVEVRSITCKDANTQRVLQEIIQETTNRLNRLQKQESENEIKVKQLEGEIVAQETRSRLLELQRRIAQAEAETQGLAEAERVHAFIQGLGAELPISEKLAIFNILRRQEAIASLSQGKAQLYLTPADINLSLEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUT0</accession>
    <name>A9AUT0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cysteine desulfurase IscS</fullName>
            <ecNumber evidence="7">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">iscS</name>
        <name evidence="10" type="ordered locus">Haur_3884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3884"/>
    <dbReference type="EnsemblBacteria" id="ABX06518">
        <property type="protein sequence ID" value="ABX06518"/>
        <property type="gene ID" value="Haur_3884"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3884"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_0"/>
    <dbReference type="OMA" id="KGLYWAR"/>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017772">
        <property type="entry name" value="Cys_deSase_NifS_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03402">
        <property type="entry name" value="FeS_nifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="7">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="7">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="7">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared with IscU</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="398" mass="42900" checksum="53F9D050DF74F0B8" modified="2008-01-15" version="1">MAPETIYLDHAATTATDPRVVEAMLPYFNTAYGNPSSIYRLGRAALEGVDEARETVASLLGAKRKEIVFTSGGSEADNLAIKGVAFAQRDAGKGNHIITSAIEHHAVLHAVEYLEHFGFEITILPVDSTGLVAVADLRAAIRPTTVLVSIMAANNEIGTIQPIAELGAVCREHNVLFHTDAVQLIGAQPINVKELNVDLLSLTAHKFYGPKGVGALYMRRGVPLLPLINGGSQERRLRAGTENVPGIVGLAKALQLAVDELPQSSNQLTSLRDRLISGIEAAIPHVYLNGHRSQRLPNNVNMSFDFIEGESMLLLLDQQGIYASSGSACTSGSLDPSHVLMALGLSAERAHGSLRMTLGRENTAEQIERVLALLPPIVERLRAVSPMYRHFLAEQTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUX5</accession>
    <name>A9AUX5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3929"/>
    <dbReference type="EnsemblBacteria" id="ABX06563">
        <property type="protein sequence ID" value="ABX06563"/>
        <property type="gene ID" value="Haur_3929"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3929"/>
    <dbReference type="HOGENOM" id="CLU_1728852_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3971-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734348" evidence="2">
        <location>
            <begin position="24"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="15177" checksum="4C3469A3A2736DC2" modified="2008-01-15" version="1">MSNSPKRRSSLMLNTSMSVAAIAATLTGWAVLSNQQAVDFSAELATPEPIVAVAEVPQVELPVLPTVAPLTRNGHRIIRIPNDSAGGSTQPSAPNQSVPSAPATGGGSSNVPSQAAPQPAAPRQVAPVPTAVPAPAPAAPAAPSRNTRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV09</accession>
    <name>A9AV09_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3965"/>
    <dbReference type="EnsemblBacteria" id="ABX06597">
        <property type="protein sequence ID" value="ABX06597"/>
        <property type="gene ID" value="Haur_3965"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3965"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_29_0_0"/>
    <dbReference type="OMA" id="ITGLEWI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4007-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
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        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="2705"/>
            <end position="2726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="2855"/>
            <end position="2874"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1445"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2985"/>
            <end position="3060"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="4538"/>
            <end position="4614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="4510"/>
            <end position="4531"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1480"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3020"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="4573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="4646" mass="496626" checksum="8A9064A8AB048D97" modified="2008-01-15" version="1">[encoded data, 4646 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV17</accession>
    <name>A9AV17_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3973</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3973"/>
    <dbReference type="EnsemblBacteria" id="ABX06605">
        <property type="protein sequence ID" value="ABX06605"/>
        <property type="gene ID" value="Haur_3973"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3973"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_222916_0_0_0"/>
    <dbReference type="OMA" id="DIVSWRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4015-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="527"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1569"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2613"/>
            <end position="2690"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="4177"/>
            <end position="4254"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="5243"/>
            <end position="5320"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="6310"/>
            <end position="6385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3154"/>
            <end position="3189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="3171"/>
            <end position="3189"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="562"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1606"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2650"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="4214"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="5280"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="6345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="6661" mass="721266" checksum="1268A03527E5B580" modified="2008-01-15" version="1">[encoded data, 6661 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV34</accession>
    <name>A9AV34_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0461"/>
    <dbReference type="EnsemblBacteria" id="ABX03112">
        <property type="protein sequence ID" value="ABX03112"/>
        <property type="gene ID" value="Haur_0461"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0461"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019843_1_1_0"/>
    <dbReference type="OMA" id="RMFWGDP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-467-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="34"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36864" checksum="AE3DF52A03D0C03E" modified="2008-01-15" version="1">MYSTTKNAKTREQIATMVAHAFEGMQLAPHEQAIQELKDGWFNAAYAISLADGREVVLKIAPLPDADVLSYERNIMQTEVATMRLVQQNPAIPVPTIYFFDESLSMCDSPYFFMQKIAGDNLEHVRAALEPAVQAKVDQHIGAIIHEINQFSGSYFGYEGNPKLRGDSWKATFITLIDALLADGQRKNVELEYSYAEIRAAVLKHAAALDEVTTPYLVHWDAWNANFFVEHDKIVGIIDFERALWGDPLMEAQFRPFSGESLSNFMQGYGKIAFTPAEEQRNQLYSLYLALVMAIECYYRNYDTDFVRTIARQLLGATMDWLKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV77</accession>
    <name>A9AV77_HERA2</name>
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        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0504"/>
    <dbReference type="EnsemblBacteria" id="ABX03155">
        <property type="protein sequence ID" value="ABX03155"/>
        <property type="gene ID" value="Haur_0504"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0504"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1131754_0_0_0"/>
    <dbReference type="OMA" id="EFITFTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-510-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
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    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="90"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="27819" checksum="2A1BC5D9EB8D2141" modified="2008-01-15" version="1">MKKFGLIIGGVIAIAVIGAIAYTLWLTSDVEVSTSTPVAATLVLPTTAPTTAAAPATATTASDNTAAATATTGTEPTTDASQPAAAGAKIYRIDASQSSASYQVRETFLQDNKIVDAVGVTKAIAGELLIDTATPANSQVGEIVVDISQLQSDSERRDNAIRREWLESSKYPNAVFKNGVISNLPSDLKEGVEFSFQITGDMTIHDTTNPLTFDVTATLNGDTLTGKATTKFNMSSFNVDAPDIGGMLKAEDEVLLTLDLVATAVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV83</accession>
    <name>A9AV83_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0512"/>
    <dbReference type="EnsemblBacteria" id="ABX03161">
        <property type="protein sequence ID" value="ABX03161"/>
        <property type="gene ID" value="Haur_0512"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0512"/>
    <dbReference type="HOGENOM" id="CLU_1675506_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-517-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17284" checksum="DD48108A3F86CE14" modified="2008-01-15" version="1">MYHVPNNPNIQSSFASIFDACIQRGPGLGVSIGAIYGYYFTAIYGLLVAGIIGGIVGVVGSMILAIVIYCWQQLFQTHNLGLYHLYWFAPLSIVSIYSLVGYSLLSQQANLSEYFYQLLANVTVSNQLSRFVTWPSLIIIVTLVIGLPIILEKSQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV94</accession>
    <name>A9AV94_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IstB domain protein ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0524"/>
    <dbReference type="EnsemblBacteria" id="ABX03172">
        <property type="protein sequence ID" value="ABX03172"/>
        <property type="gene ID" value="Haur_0524"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0524"/>
    <dbReference type="eggNOG" id="COG1484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_3_5_0"/>
    <dbReference type="OMA" id="YDERFLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-533-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="86"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="26612" checksum="AF2DF4963388027C" modified="2008-01-15" version="1">MTNAVWEREETITCERCQDSGVLGYRYSDDKTRKAIEYIPCDCRKPTILQKHGDLSLVAKKTFETFVSLPQVAPLAQACMDYASDPKGWLLLSGPYGCGKSHLAAAIAHAVVASGKSAMFFVVPDLFDALRETFDGQQGESFQQRFDRIRNVPLLVLDDAGTEHLTSWAKEKHFQLINHRYNRELPTVFTTNEDLKRFDGRIASRLADVALVEHLDFTGIADYRRLNLAKRRGKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA1</accession>
    <name>A9AVA1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger SWIM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03179">
        <property type="protein sequence ID" value="ABX03179"/>
        <property type="gene ID" value="Haur_0531"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0531"/>
    <dbReference type="HOGENOM" id="CLU_965664_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-540-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="31916" checksum="28A009736E74A3CE" modified="2008-01-15" version="1">MQPQETTRRELTTLSHAAVGITLWLEHNNHGWSAFLSTPKMTIQHIGSRYYEFFVDELIQHAINYADEVAEEFNPTPAAPAAPLKPAKKKPTRKQPKQPVCYCQCCSPTQGATGVTYCLKDKEYVAHNGGELIGYFPTSDAASSKLNKLRYEILSREFPEQPAHKFFEPLEDELTREPAASSASAIPQAPSYFVIGQLVGQLRQLYAGKKVQLNAINKAFSELAVPGWSWDGSSLTIRSRSNPSILYHVNGDTCQCTAFAKGATCWHRAAYKILLQAAAAPNHYQKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVE1</accession>
    <name>A9AVE1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1989"/>
    <dbReference type="EnsemblBacteria" id="ABX04632">
        <property type="protein sequence ID" value="ABX04632"/>
        <property type="gene ID" value="Haur_1989"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1989"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006968_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2018-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1205" mass="134418" checksum="F2CB1F9797EAE38C" modified="2008-01-15" version="1">MTDFLCVPIQLDGLFCPTDRLVLQPNVDPMRLPYRDGSLEHNAAQAFISENAVVQPFDNRNFYLHAGLHLHWSLPDALGFGRQTADGIRFPRVPNRWLLSRRLADGQLTQWVIESDYLYPIDARLNTHAVAIPSANPQAERPFRFLGRTLPLAQWLNAPAGERYPNLTVLGFGEPSFASFYPNSFSVFGFHDAEWQHLPPEGTTYDLLGWYSDLNDDPIRQLIAQPGLNFAPALLQAIQTNFRWQYSVDSDHLPDSSLCYGRLAIATSVLQPNLALEMPMSVAIGTTGTEALSAYLAATLAPEQKSIAEDQLEAALLADRLDHRVLDIGPAFYELRHEKGFNALNGGIRWFLRPRASSEQAQDQTEVRLPSELAHALNQLNRTQAAYDRANDEVTQRREQLFADWYKYMVAAYPPEGAIDNFPDSDLVRSFIEHYPMRQLTQALAATGELQIGFDADGELFANGGSSAAGSLAYQVAEAIQSVQQILATYNQPLPANQQLVLRQSSAPRFWQPNEPVVLLIGAAAKPSDRHGADGLLTCQLLFGHELAELWQNPATLQAVFDQLINADPTVVSRWECQPWHPLRLEWEVEVFPLDGLNTIDGHNQAIEQAFSANYSLGEQAVDLEIVPERQHLTRSASLYSGFSLLTGHAATQYQRQLAAFQQSALADSSFSIYQQAAEHINHPNFHCLAQSLGGFNAALLMQRQTYQLPIREPLGFADYQAFTAQVAQAVAAENWAAPQPLNDFLPIRTGAVRLQRLRLVDNFGQVHDLDCSQVIRPEAMQTPANPSLVWLPPRFVQPSRVNLRWLAAADQQLEMNDHPLTSPICGWFLPNLLDQSVEIYAADGQALGLIDRRGHWQMAPANTQPATPEAIEQPILRQTVQRLIAAGSDFLQAWLDGIEQAAQTIAPEQATQHNQLALLIGHPLALVQASLDVELQGLPALDQSWNSLRADLQTSQRDNDRFAYARVPLRLGEYHRFNDGLIGYWLTDDVNFYLPQVHTSAHELLKTHSEAPLNIPLSPLDPALIVTMLVDPRGHVHVASGINPLKSISIPAEQYQDALGALAMSFLTAPILSDDIVRLPQPTVPGYSWQWVERHAETWRVLGQQGQLSFATVQAFVGEQAAEVWQWLHNAGWLTTIDPSTALVVARDQRPHAEVPTTIQPLLPALEYLLETTYLHQPDGQASFARRLQLREGWLRLQPQAQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF4</accession>
    <name>A9AVF4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04645">
        <property type="protein sequence ID" value="ABX04645"/>
        <property type="gene ID" value="Haur_2002"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2002"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091687_2_1_0"/>
    <dbReference type="OMA" id="HFANKQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2031-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041479">
        <property type="entry name" value="TetR_CgmR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17937">
        <property type="entry name" value="TetR_C_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="20225" checksum="E4B6F64E6445984F" modified="2008-01-15" version="1">MTKKNPQATKAKLLHALIAVIMRDGAANVTLEAIAKEASVSKGGLLHHFPTKESLFQGLLDLAKQAWETCLAGELAKESPDVAGYWCRAYVHASFSQPPKDIQMLHAVRRVVAIYPELFDYWRETYVQTTPAPANDGLTLGRSLTIQLACDSLWFSELIGLPIISAAAQQALYDELLRLTYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF8</accession>
    <name>A9AVF8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2006"/>
    <dbReference type="EnsemblBacteria" id="ABX04649">
        <property type="protein sequence ID" value="ABX04649"/>
        <property type="gene ID" value="Haur_2006"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2006"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_5_2_0"/>
    <dbReference type="OMA" id="IHHICYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2035-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15436" checksum="3B9E8A332194E1B5" modified="2008-01-15" version="1">MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIAPTSPDAAFAKFLAERGEGIHHVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFIHPKALHGVLTELVEHPKATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI2</accession>
    <name>A9AVI2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2030"/>
    <dbReference type="EnsemblBacteria" id="ABX04673">
        <property type="protein sequence ID" value="ABX04673"/>
        <property type="gene ID" value="Haur_2030"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2030"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_12_0"/>
    <dbReference type="OMA" id="ANAPYYY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2059-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="461"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="550" mass="60446" checksum="F8ADDD618CD75A04" modified="2008-01-15" version="1">MMIEFNQMLEVVPPCQSEPNQAHATSQLHSGFLQSVQRYPNNIALTIGNKQYDYVKLYTVAQRWAFALRQSTKPLHRVGIFAYRSEAAYIGILASLLAGATFVPLNYNFPLQRTQAMIEQAELDAIIVDHQSYDQFLQLADSLPVLPPCVLLPDCLRAPLLDTMIYTQAELAELPTDHEPVTVPPEAIAYLLFTSGSTGNPKGVPISHANVAHFLKVNQARYQITPADRLSQTFDQTFDLAIFDLFMAWNHGAAVCVIQPIQLLSPFRLIEEQGITIWFSVPSVAALLRKQKLLKPNSLPNLRLSLFCGEALPKATAEAWQLAAPNSIIDNLYGPTELTIACAVYRWNSLTSPAECLNEVVPIGKLYPGLTAVVVDANDNPVPAGTEGELCVAGPQTFQGYWHNPSLTEQRFLRSKQLNGEELGYYRTGDRVVCRTNGSMIYLGRSDQQIKVHGYRVELSEIEGALLLQPGVVAAVALGWPLENGSASGIVAFVIAPSIAVSDLQQAVQPLLPSYMLPRTIYQLETMPLNANGKIDRLALARHLAGEGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI7</accession>
    <name>A9AVI7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilT protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2035"/>
    <dbReference type="EnsemblBacteria" id="ABX04678">
        <property type="protein sequence ID" value="ABX04678"/>
        <property type="gene ID" value="Haur_2035"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2035"/>
    <dbReference type="eggNOG" id="COG1848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125353_0_0_0"/>
    <dbReference type="OMA" id="WIYHIED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2064-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="14"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="16610" checksum="6FBB085F2FA565B6" modified="2008-01-15" version="1">MSVLTTLAPIRRLYFDTAPLIYYTEGHAQYLPTLRVIMGQIAPDQIHAITSVLTLTETLMKPLQQQQMALVHQYRLLFYQTAALTMVPITAPIAELAATLRAQYGLRTPDALQLATAIDAGCDAFLTNDFALQRVTEIPVLVVDALANVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW58</accession>
    <name>A9AW58_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2068"/>
    <dbReference type="EnsemblBacteria" id="ABX04708">
        <property type="protein sequence ID" value="ABX04708"/>
        <property type="gene ID" value="Haur_2068"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2068"/>
    <dbReference type="eggNOG" id="COG2963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117165_2_0_0"/>
    <dbReference type="OMA" id="SHILEWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2096-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15287" checksum="991D07D9850F2AA0" modified="2008-01-15" version="1">MASKKTTPDQSTHDPEVRPKAARTHWSARDRLRILAAADACAPGELGALMRREGIYSSHLARWRRQRAEGELAALTPKRKAAPTPEAQRQTAELARLRRENQRLQAKLAQAEVIIDVQKKLATLLGITLPAPPTDAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA2</accession>
    <name>A9AWA2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2112</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2112"/>
    <dbReference type="EnsemblBacteria" id="ABX04752">
        <property type="protein sequence ID" value="ABX04752"/>
        <property type="gene ID" value="Haur_2112"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2112"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="QSPMVML"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2140-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="36679" checksum="FEBA94678E528CEC" modified="2008-01-15" version="1">MNQPVLATDNLSVGYHQRRGQSRSVLQNLNLSLAKGEFVCLLGANGAGKSTLIRTLTHMQAPISGSVTINQQPLHHLSKAQLAKQLSVVLTDRLQVSNLTGYELVSLGRMPYTNLFGSLNQHDHQVVRWALHATNSDDLAQRLLNEMSDGERQRIMIARALAQEPAVMILDEPTAFLDLPRRVEITSLLRKLAHETGLSVVMSTHDLDLAIGSADRLWLVFDDGSIECGTPEDLILDGRLAQTFRKSQLQFDQQRGGFRAQTQPIGQVRLSANGLHGQWMQHALERAGYHVLNAKQADCPHIQQLENDCWQVEHQPCANIDQVLAYLGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE2</accession>
    <name>A9AWE2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetylmuramoyl-L-alanine amidase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2152"/>
    <dbReference type="EnsemblBacteria" id="ABX04792">
        <property type="protein sequence ID" value="ABX04792"/>
        <property type="gene ID" value="Haur_2152"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2152"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_752032_0_0_0"/>
    <dbReference type="OMA" id="IVHHMAF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2180-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGRP" evidence="3">
        <location>
            <begin position="40"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="38222" checksum="43DAEC25E776F25A" modified="2008-01-15" version="1">MKKLSRRTFGKLSLGVAMSVVVGGTELRLLRPAYAAVATPAIDSTTAWGAAAAKEPINVLNQKPIGIVVHHTTNPNTNDFTRNKAWQVARQIQQSHFNRGWIDTGQQFTISRGGWIMEGRHQSLSILQGGTKHVQGAHVDGHNETHIGIECEGLYMNVTPSLPLWNKLVALIAYICQQYGLTANAIVGHRDLDSTSCPGDTLYSLLPQLRTAVDTTLSGGAVGRMWPILRRNTPATGLAKTMQYLLRARGATITADGAFGPGTETAVKSFQTANGLTSDGVVGAATWEKLIMTLRSGDTGEAVKALQNQLTVQSYPTTIDGSFGTGVNTLVRAFQTNRQLTVDGVVGLNSWNNLAM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL1</accession>
    <name>ARLY_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Argininosuccinate lyase</fullName>
            <shortName evidence="1">ASAL</shortName>
            <ecNumber evidence="1">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argH</name>
        <name type="ordered locus">Haur_4138</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AWL1"/>
    <dbReference type="SMR" id="A9AWL1"/>
    <dbReference type="STRING" id="316274.Haur_4138"/>
    <dbReference type="EnsemblBacteria" id="ABX06770">
        <property type="protein sequence ID" value="ABX06770"/>
        <property type="gene ID" value="Haur_4138"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4138"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_1_0"/>
    <dbReference type="OMA" id="KKNPDVF"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000089086" description="Argininosuccinate lyase">
        <location>
            <begin position="1"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <sequence length="454" mass="49448" checksum="A81781FE849ACF81" modified="2008-01-15" version="1">MWGGRFSGSLAEHMRLFNDSFPIDRRLWAEDIRGSIAWANGLERAGILQAAECQELIAGLRQVYQEFEEGLFLPLTSDEDIHTAVERRLGDFIGALAGKLHTGRSRNDQVATDTRLWTLGALKLADDLIRDVQAALLEQAKAVGEAMLPGYTHLQRAQPVLLSHALLAHFWRLDRDRQRLHDATKRVSVLPLGSGALAGTAFAVDRAALAAELGFTSISQNSLDATSDRDYIVEILAAIALLGVHISQLAEDWIIWSSSEWGFVALDDAYSTGSSLMPQKKNPDSLELARGKSGRLIGNLITVLTLLKGLPSAYDKDLQEDKAPLFDAIDTLSLTLPVVAGAIRTARFNTERMESALDDAMLATDVADELVRRGVPFREAHHIAGRLVREAEQRGVGMRQLPAESFVAAHPSLTDVAGLFDFARSVAMRDVPGGTAPNAVRDQLIAAQHVLAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR4</accession>
    <name>A9AWR4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0667"/>
    <dbReference type="EnsemblBacteria" id="ABX03315">
        <property type="protein sequence ID" value="ABX03315"/>
        <property type="gene ID" value="Haur_0667"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0667"/>
    <dbReference type="HOGENOM" id="CLU_1793849_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-678-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="144" mass="16015" checksum="84FBF38762823FBB" modified="2008-01-15" version="1">MADELANERYASESIPDKDFLYMRVHKSFIQNGNPGYGAFKPQGDGLSTDWDNYSTPQETRARATSTKDLPINLYAVVKMSVALVRAITELTVVHTPINKDEENGPNQAHTDIKGIDMANRVQANVLRRKLSEIAPIVLDVGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV1</accession>
    <name>A9AWV1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0704</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0704"/>
    <dbReference type="EnsemblBacteria" id="ABX03352">
        <property type="protein sequence ID" value="ABX03352"/>
        <property type="gene ID" value="Haur_0704"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0704"/>
    <dbReference type="eggNOG" id="COG0605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_0_1_0"/>
    <dbReference type="OMA" id="KWGSFDK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-716-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="97"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="22350" checksum="CB20CA995BE607DA" modified="2008-01-15" version="1">MAFELPALPYATDALEKAIDAQTMEIHHGKHHAAYVNNLNAALEKYPELQSKSLHELISDLNSLPEDIRTAVRNNGGGHANHSLFWNILSPNGGGEPTGKLGDEINATFGSLDAFKEQFAKAATTRFGSGWAWLIRTSEGKLAVTSTANQDSPVMEGQTPLLGLDVWEHAYYLRYQNRRPDYIKTWWEVLDWNKVAENDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW6</accession>
    <name>A9AWW6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0719"/>
    <dbReference type="EnsemblBacteria" id="ABX03367">
        <property type="protein sequence ID" value="ABX03367"/>
        <property type="gene ID" value="Haur_0719"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0719"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_72_0"/>
    <dbReference type="OMA" id="HALVWVI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-731-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="316"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="531" mass="59332" checksum="75512CF53CDA8E2C" modified="2008-01-15" version="1">MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMPEMDGYQTLQAIRERNHLPFIPIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMRVLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLPEALNAINELLGASRGSVLLLDDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYDDREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVYTRLREAEDSRDSFIQMLTHDLRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQRLIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGITVEQQLSFELDLPAEPLVVLDEHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDKFYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWX2</accession>
    <name>A9AWX2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0725</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0725"/>
    <dbReference type="EnsemblBacteria" id="ABX03373">
        <property type="protein sequence ID" value="ABX03373"/>
        <property type="gene ID" value="Haur_0725"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0725"/>
    <dbReference type="eggNOG" id="COG0643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000650_2_1_0"/>
    <dbReference type="OMA" id="MMDMAKS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-737-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="233"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="9">
        <location>
            <begin position="491"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="643"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="221"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX03373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="762" mass="82365" checksum="8ABAB383E39D4D92" modified="2008-01-15" version="1">MGGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQVDMGRLAHTMESLLSALRSGMLAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLVEQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEPAVAKPAAPAKPKKSASAEAPKSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSERLTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMATRLQPVAGLFAPIPRAVRELARSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALDHGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGRGIDPAVIRATAIKRGIIEADTAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTTFTLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSIVALAPLLEQRGPLPQPSDISNLVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLCTGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQPAKLLVAEDSFTTRELLRSMLQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIIIITSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX12</accession>
    <name>A9AX12_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04820">
        <property type="protein sequence ID" value="ABX04820"/>
        <property type="gene ID" value="Haur_2180"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2180"/>
    <dbReference type="HOGENOM" id="CLU_2154881_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2208-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="12927" checksum="F4C78937DEE419B4" modified="2008-01-15" version="1">MRNIRLETSSIDNQATLSSALDRLMAYPGWYQRECEPWLDLVSYFDSQHSLQPHKTRKAGFEQFIIEIVGAESFWTKYPKLANLLIKWIADVNKRAMQRSGQAIIRLTLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX69</accession>
    <name>A9AX69_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04877">
        <property type="protein sequence ID" value="ABX04877"/>
        <property type="gene ID" value="Haur_2237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2237"/>
    <dbReference type="HOGENOM" id="CLU_2058135_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2265-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13518" checksum="886E9609E97EDE6E" modified="2008-01-15" version="1">MTYPLIKEYVFDLQQKLPSLHNIVLSHPDFMAAANDNHAIVRLPHGIQITKNLILTLNEPIDTYIIFRDLQQTFALFAVNSKTVLICYSDTSLRLGMLISDLIMSAREIRDLLTNGTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR3</accession>
    <name>A9AXR3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX03477">
        <property type="protein sequence ID" value="ABX03477"/>
        <property type="gene ID" value="Haur_0829"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0829"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-843-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
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    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="457" mass="50623" checksum="EC07DC19AF20B2B5" modified="2008-01-15" version="1">MGHDHALVIGASISGLATAQILSHYFAQVTIIERDSLPDSIEVRSGLPQARHLHLLLMRGARELETLFPGIGQELVAHGAQSVDLMNDYRYLMAGGWAKPHQSTHRTISASRPLYDWVLLQRLRQNPKIRIETQTDVLGLVGDLRHVRGINTKRRDTGVEQQFLAELLVDCSGRSSKLDQWLQALGCQAVPETVIASNVGYCSRLYAKPEGWNEWKGLFVRQRPLVNPRGAILTEIEGNRWMVTCGGFNEAKPPLDESEWLNWLNQLRSPILYELLSKAQPISPLVGFGRTENRQRHYERISLPAGVVALGDAVCAFNPIYGQGISNATLGAILLSQHLKEQDRASAAWGQRFQQALAKSNQFPWSIAVGEDARYNTSVKRSFGATLLRNYFDQINLASSSNPVVLNRFTPIVHMTGNPSGLLHPAMIWNVIKGRLRSATPNPTPSIPSILSASQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU6</accession>
    <name>A9AXU6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2272"/>
    <dbReference type="EnsemblBacteria" id="ABX04912">
        <property type="protein sequence ID" value="ABX04912"/>
        <property type="gene ID" value="Haur_2272"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2272"/>
    <dbReference type="HOGENOM" id="CLU_729142_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2300-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="42524" checksum="01DCE7D7EBEEB15E" modified="2008-01-15" version="1">MDGLNKPHSRRKFLTTSGLAAVAAGSVLGKHGQAAAAPASAPNSGLTATNAMELPPSAKISIRCLRSLTMLTMSSQLTDPAFSAEVYEIGLKDLESNLQELIGLGTSDLVSYRPNPEESLPTRPWWWPKRRVRHYRGQLSHESIPDAGQLILDIIRSLDGYTVAFYSQQLEFAELSQHLALVEMQTQFQRLINAPSLAGLFPDDDDICPWWWPYPQPNWLHLHDRDWPVPPIPIPPCDLRELAVNVQRGLIQLAVAERYSDSEQASYRRDSIRPTIHDLANQLSAYAGTLTGWLEHDIVDRPPPDPNDPYPWPFHDGLIDELVDFADRPPPQPYRIKLGDQIMRASHLVGVACHIRERHLAGRLQDASLTQIKDLAYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY1</accession>
    <name>A9AXY1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2307</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2307"/>
    <dbReference type="EnsemblBacteria" id="ABX04947">
        <property type="protein sequence ID" value="ABX04947"/>
        <property type="gene ID" value="Haur_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2307"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_412051_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2335-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="389"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="449"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="666" mass="72735" checksum="FD41D4BFA39DB853" modified="2008-01-15" version="1">MGKSLRWKLGAAFGLVISATLLLSGLSAYLLTTQRFDIFVGDQSQLRTEQLAPWLEASHAYNADWSAISTLLRQSENLSQTHTLSLAPAIFSIDSGQLWQDSAEVIGISPEHLQGEVGSGGSIESVALAHNVDPEALIVSLEQAQLPMTTIPTTMAVVGATPTGAGIDLQSQIRYFVEYQTSPDWLSLIQKQLNASPAEIQQSLQHPQGFVALAQRYQSEPRLLVQAIVEAELARLKSMSSIPISSILNELPLIAQSAWSFIDPQGLAQPNNSRMGLLHHDSMLLQWELQALLHGDERLIILDPMGNVSYDSAQQLNNDQQLDNDLRQHAVPLYDLISNQPIGSALIVTGTHAYTEHQGAFLRSTGQALVMSGGIVGMIVLALGFVLVRTITAPVLALIQATKQIIAGNWQTQVPIRSHDELGQMSKAFNHMANSLAQQRMLQTRLIHDLTHELHTPLSVIQLEMEGLADQLQSADEAARHVEHEIKLIVSLLDDLTLLLKTESHSLEFNQEALDVEQLLHETHQRWQQPALNAGIQLKLSIEQPLPKIAVDRTRIVQALGNLLKNAIRHTPANGTISISCSSDQSSINLSIHDTGEGIAAHDLPHIFERFYRADASRNRDTGGRGLGLAIVKQIIEAHGGTIEVSSTLGQGSNFQISLPINPSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY03</accession>
    <name>A9AY03_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cobyrinic acid a,c-diamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbiA</name>
        <name evidence="6" type="ordered locus">Haur_2329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine = 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:26289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="ChEBI" id="CHEBI:58894"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 10/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.11" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2329"/>
    <dbReference type="EnsemblBacteria" id="ABX04969">
        <property type="protein sequence ID" value="ABX04969"/>
        <property type="gene ID" value="Haur_2329"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2329"/>
    <dbReference type="eggNOG" id="COG1797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022752_2_0_0"/>
    <dbReference type="OMA" id="QPFKCGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2357-MON"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="251"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="454" mass="48556" checksum="E3DB46B5FB52D916" modified="2008-01-15" version="1">MTARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNLDAWLFTPEQLQRHFCQIAAPADLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVVDAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHADLCATAIEQHTGIKCLGYLPRQAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPISPIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGGYPELYAAELSTNQAMLNALRQAHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGSSQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWENPEPATAAYCIIAPDGTPQQHEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY35</accession>
    <name>A9AY35_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome oxidase assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4285"/>
    <dbReference type="EnsemblBacteria" id="ABX06917">
        <property type="protein sequence ID" value="ABX06917"/>
        <property type="gene ID" value="Haur_4285"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4285"/>
    <dbReference type="eggNOG" id="COG1612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041525_1_0_0"/>
    <dbReference type="OMA" id="HRYFAGT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4337-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="37798" checksum="94A282243F839805" modified="2008-01-15" version="1">MEQMRVPTDQVRFSWRRLDRFQKWAMITTIATYFLIFVGGIVRASGAGLGCPDWPKCFGYWIPPASADMIAQHGFDASQFNPTLMWIEYINRLIGMLIGFFLLITTYLMLRHYRKSKRVFWSVLGALALTLFQGWLGGKVVHLELEGWIVTLHMILALVIVGLLLYATVCAFFPNGRPIANVPAERRTVARWGQALVGFGLVQLTLGALVRGHIDDVSSKMNIPRSDWVSQVGITDPLHRTGALIFTISILAATYAIVHNRSLHPWIHRTAWIASGLVLTQVAAGIGLAYGALPPPLQAIHLIVGSLLIGCLMTLVLLAYRLPVSPSTSKEAFKQVAEASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY36</accession>
    <name>A9AY36_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HhH-GPD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4286"/>
    <dbReference type="EnsemblBacteria" id="ABX06918">
        <property type="protein sequence ID" value="ABX06918"/>
        <property type="gene ID" value="Haur_4286"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4286"/>
    <dbReference type="eggNOG" id="COG0177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4338-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="6">
        <location>
            <begin position="39"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="25102" checksum="902B6E09FEF271B2" modified="2008-01-15" version="1">MQDLQAKADLVYRELVALHGFNQLVPRREPMHELISTMLSHQTTEANEERGYQNLRATFPTWEAILAAPVEAVAEAIKPANYAPAKANNIQAALAKILAERGEISIDFLAELSTEAAMAWLTGLRGVGPKTASLVLLFCFSKPILPVDTHVHRVSQRLGLVKAKTPTEAHEILWQLLPHDAEWLFNYHVALLRHGQRICLAKRPRCNQCPLTAQCLWYQANQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY46</accession>
    <name>A9AY46_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4296"/>
    <dbReference type="EnsemblBacteria" id="ABX06928">
        <property type="protein sequence ID" value="ABX06928"/>
        <property type="gene ID" value="Haur_4296"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4296"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430714_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4348-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732239" evidence="1">
        <location>
            <begin position="24"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="642" mass="71368" checksum="E3A7067BE57BADB2" modified="2008-01-15" version="1">MMKRWMLFVLMVASLGLPQASRAAEQQCFEQTGFCIEGRFAEYWQQNGGLQVFGYPLSSAQDGYNHDSQKAFLTQQFERARFELHPEFAAPYDVLLGRLGDDLLRYRNIDSPMLPREAGATSGCLWFETTGHNVCNQANGLGFMSYWQNHGLNDPKLDAFGRSLQLFGYPLTEPAIETNANGDRVLTQYFERARFEWHPTQPDQFKVLLGLVGKESLQLPYGASAEPLELTLVGDTLFFTADDGVHGRELWTSDGTEAGTRLVKDLKVGAESNWPYQLAAAKYGVFFLQLNETAYELWFSDGSAANTRMVKSIQANSNPYITNLIALGDGVLFFANDGLSGLEPWYSDGTAAGTRLLRDINPGAGHSNVETGYSYFWTEYTPMAGGMAFLARNAQAGAQVWWTDGTEAGTRQISNFAGEIHSVFELEPLDAQHLIVAASNEGTFGIWKLNMSTGEQQNLATYPWITGSIRNPIPASQLTQVNGEVFYTVISQGVGTSLWRTNGQKAQVVDLAGKSPYRLLSANNTFYLQLYQGTEQAGWWILNADASLRQFSSLDLMLADTGQGLIGWELLSNRVRVYRSTADYQAMHYQGSVLSQSSFTFYPSDTASNSQRSFFSLPDQQHGTELWVSDAQGLRLVKDIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY56</accession>
    <name>A9AY56_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4306</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4306"/>
    <dbReference type="EnsemblBacteria" id="ABX06938">
        <property type="protein sequence ID" value="ABX06938"/>
        <property type="gene ID" value="Haur_4306"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4306"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_1_0"/>
    <dbReference type="OMA" id="RKGSYFF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4358-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="465" mass="48386" checksum="352688C6825B09D4" modified="2008-01-15" version="1">MARSNSWLDAGLAGYFRFAERGTNLRTEILAGVTTFFVMAYIIFVNPSILSSGPLAEAGPPFNATLTATCLVSALMCIAMGLFTNYPFALAPGLGLNAVVAFQLILTMGLPWQAAMGVIVLEGVLITALVLTGFRQAVMHAIPLSQKRAISVGIGLFILFIGLNNAGIVQRGAGTPMALGNFTTFSILLTVVGLFLTLILMARKVKAALLIGILATTVIGVVSHYAFGADASAQAGVQGAFPTELASPSFETIGQGLNFDVFKLAGVLSAVLVIFSLMLSDFFDTMGTIIGVGEQAGFVKADGDLPNSNRVLMVDSVAAVAGGVFGTSSVTTYIESAAGVGEGGRTGLTAVVTGILFLLSILIAPFAGVVPSEATAPALIIVGFLMCGGIREIDFGELEEGFPALLTMTIMPFSYSITNGIGAGFISYVVLKLALGKAKQVHPLLWFVAVAFLVYFLLPLIEAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYK0</accession>
    <name>A9AYK0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0934"/>
    <dbReference type="EnsemblBacteria" id="ABX03582">
        <property type="protein sequence ID" value="ABX03582"/>
        <property type="gene ID" value="Haur_0934"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0934"/>
    <dbReference type="eggNOG" id="ENOG5034B45">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171740_0_0_0"/>
    <dbReference type="OMA" id="FDPEYRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-948-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12897" checksum="0647AD4CEDC15243" modified="2008-01-15" version="1">MQFDRAGKRASKLINDYQLTDEEIHQIIASARINLATFDPEYKTNVTQLAHELSKSRPTIYGWADRAIVATIDSLRNIRTGRPPKEARSRLKRLRARPTARLRRRSSDSSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ2</accession>
    <name>A9AYQ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase and serine/threonine protein kinase with TPR repeats</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2390"/>
    <dbReference type="EnsemblBacteria" id="ABX05030">
        <property type="protein sequence ID" value="ABX05030"/>
        <property type="gene ID" value="Haur_2390"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2390"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468315_0_0_0"/>
    <dbReference type="OMA" id="TTEMRTR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2418-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="459"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="600" mass="67928" checksum="C304BD4F22204E32" modified="2008-01-15" version="1">MNHATTLAALHAALAEIHNPMQHVDVLNRLVAELRLVDHEQAWALNHQAEGLARMAGDDGKPYTQGLIDCFYWRSKLLFSEQSYHQALTYLFRASKLCQLTPPRQPNPHWLDILDTSFQSASLGSEDSDAFLASGIHSAAVHNALGVLLIVLGNYTEALQYLQRAKRDAIQLNDQWFEALVCNNLGFLHCELQSPEIALNDLAHGLRLLEAMAQFPAHLRMRAEILDNSGRAACALKQFEQAVSYGEQALALYHEIDWQHGQAECHNNLGLAYAGLDQQNRAIEHFMQAYELACGSNNIHEAIEALIRHGVLLNRIKHYQAARVILEQALISVNPTINQQKVYRAHQALADTYEALGDFKASLKHYKAYYELKDTVFNEQSVRRMQVLQTMYRLDEARNQAALYHLQNDDLHQQLADIQQINLQLAEWAKTDSLTEILNRRGLYEQIDLALQHQQTDAQGWAWIMFDIDFFKAINDSYGHDSGDEVLRGIAQRARLVLRHSDVFGRYGGEEFLVFLPHTSMQEAIVIAERLRTAIANTPYVVKQTAVNVTISLGIAWTEQVDDPERLTQLADQALYRSKAAGRNCYTIERFDAPVSQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU2</accession>
    <name>A9AYU2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2430"/>
    <dbReference type="EnsemblBacteria" id="ABX05070">
        <property type="protein sequence ID" value="ABX05070"/>
        <property type="gene ID" value="Haur_2430"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2430"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_0"/>
    <dbReference type="OMA" id="AVLCHYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2458-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20681" checksum="922177E9B9A413D9" modified="2008-01-15" version="1">MLKGNLVTLRSIEREDSKILHELEKNVELVLLGDGTWSPTSLASIEKRFEKHLENPEKSWFIIEVEGVVIGTIGLHHQDRVAQCSEFGIGIYHPDYVGKGYGSDAIQVLLGWAFRIQNYRRIWLTTGSNNPRAVAAYEKCGFIHEGRLRQHFYNNGEYVDVIQMGMLRSEWEAKRPEHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ43</accession>
    <name>A9AZ43_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0941"/>
    <dbReference type="EnsemblBacteria" id="ABX03589">
        <property type="protein sequence ID" value="ABX03589"/>
        <property type="gene ID" value="Haur_0941"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0941"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_771104_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-955-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="311"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="39133" checksum="B81810AB3262C11F" modified="2008-01-15" version="1">MASTKQQLQQAINQALPEQQLSYSQQQVINQALEQQLEQVRQLQPTRDRRKAPKTKRRIWQWQWSRAQIFALIVATALLFFVTYATLATSAPSVPHNASVQIFDGTAVINNLRTGAERRLNAGDVTILEPGDTIQTETGRALITYFDGQTTTLQANARLTLETMDSQNGGQQIRLKVWFGRTLNGVKRLLGPNDQFEVETPSSAASVRGTEFTVESRNNTTTFYATDKGNVQVAMDGQTVFVRAGEQLLAEQSKPLVVQPQISPTNTPTNTPTPTATATPTNTPTNTPTPTATTTATPTATPSATPTATPQLYITQAGDTINGIAQRFGITPDALVNANPIIRDRDEIPIGLTLIIPQP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ72</accession>
    <name>AROA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="1">EPSP synthase</shortName>
            <shortName evidence="1">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroA</name>
        <name type="ordered locus">Haur_0970</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPSP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZ72"/>
    <dbReference type="SMR" id="A9AZ72"/>
    <dbReference type="STRING" id="316274.Haur_0970"/>
    <dbReference type="PRIDE" id="A9AZ72"/>
    <dbReference type="EnsemblBacteria" id="ABX03618">
        <property type="protein sequence ID" value="ABX03618"/>
        <property type="gene ID" value="Haur_0970"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0970"/>
    <dbReference type="eggNOG" id="COG0128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024321_0_1_0"/>
    <dbReference type="OMA" id="YEDHRMA"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000099708" description="3-phosphoshikimate 1-carboxyvinyltransferase">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="1">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <sequence length="431" mass="45381" checksum="DD180921FF9A8119" modified="2008-01-15" version="1">MKQTVSHAKRLRGAISVPGDKSISHRSVLFNALAEGNAEITGFLPGADCLSSIACLRQMGVEIEHSDDKVRVFGRGLRGLREPSDVLDCGNSGTTLRLLAGLLAGQPFLSVLTGDASLRSRPQKRIVEPLRQLGAKLDGRDNGNRAPLVIRGTTIHGGNYELPIASAQVKSALLLAGLTGDAPMRLSGKIVSRDHTERMLIAMGIDLTVKDDEIVLYPPSHPVFPYPLSLHVPGDPSSATFWWVAAAIHPDAEITTLGVGLNPSRTGALDVLKAMGADITISNERNEGAEPVGDVTVRGGGLRGTRIDGDLIPRLIDEIPVLAVAAACAVGETVVADAEELRAKETDRVATVVSELTAMGATLEATPDGMIIAGGGELQGAHVQSHGDHRIAMALAVAGLVAEGETIIDEAEAVTVSYPTFWQHYAQIKEA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE9</accession>
    <name>URED_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urease accessory protein UreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ureD</name>
        <name type="ordered locus">Haur_2455</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZE9"/>
    <dbReference type="SMR" id="A9AZE9"/>
    <dbReference type="STRING" id="316274.Haur_2455"/>
    <dbReference type="EnsemblBacteria" id="ABX05093">
        <property type="protein sequence ID" value="ABX05093"/>
        <property type="gene ID" value="Haur_2455"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2455"/>
    <dbReference type="eggNOG" id="COG0829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056339_5_1_0"/>
    <dbReference type="OMA" id="LMVFIVN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="PTHR33643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0996">Nickel insertion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000346568" description="Urease accessory protein UreD">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01384"/>
        </source>
    </evidence>
    <sequence length="287" mass="32447" checksum="48C08E8B0EEF07E9" modified="2008-01-15" version="1">MQTATRLERMHGHLALDFTLKQQRTRLTVREHRPPLQVVRDFGLADGTSFVHLHNVAGGVLAGDQLTTTIKLAASTKAQLTTTSSTRIYRSDGEQIAYQQVQATLAEQSLLEYWPDTTIPFAESLYQQQTRIDLAADAGLCWWEFLAPGREAYGERFAYRQLRLDCDIYALGRPILLDRMRLQPSLQQLSNPLYFGKYSYLATGYICRVGWDAVQWKALEAELMAFAASQTKLGRCLWGVSCLAAHGLVIRGLSSNSRDLLATAFDYWRFAKQALYGTTPNLPRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL3</accession>
    <name>A9AZL3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2519"/>
    <dbReference type="EnsemblBacteria" id="ABX05157">
        <property type="protein sequence ID" value="ABX05157"/>
        <property type="gene ID" value="Haur_2519"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2519"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046029_0_0_0"/>
    <dbReference type="OMA" id="LQHDIFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2547-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016584">
        <property type="entry name" value="MeTrfase_VrtF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011491">
        <property type="entry name" value="Mtase_YbcY_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="1">
        <location>
            <begin position="52"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="215" mass="23978" checksum="6D00C3B5DC8F79E4" modified="2008-01-15" version="1">MSDLPASARIYNNNLLKFYDFLVHGISDSFIWRCPKPNLVAWYRQHLGKQHLDIGPGSGLLLRETLNQQQLSKLVLLDVNPACLIQASANLSEWQPQAVRASIMQTLPLTEQFDSIGLGYIVHCIAGTPDIKGAVLQRLAELLTPNGVLFGATILSASEPFHSATARRLMGIYNQRQIFANQTDTLAKLETMLQQAFQLYEIKRIGSVALFAGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP6</accession>
    <name>A9AZP6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="6">SDH</shortName>
            <ecNumber evidence="3 6">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aroE</name>
        <name evidence="10" type="ordered locus">Haur_4468</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3 6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4468"/>
    <dbReference type="EnsemblBacteria" id="ABX07100">
        <property type="protein sequence ID" value="ABX07100"/>
        <property type="gene ID" value="Haur_4468"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4468"/>
    <dbReference type="eggNOG" id="COG0169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044063_0_1_0"/>
    <dbReference type="OMA" id="FGNPIKH"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="7">
        <location>
            <begin position="119"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="9">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="6">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="129"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="28431" checksum="FAF1837298EDE395" modified="2008-01-15" version="1">MSQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLGANVTLPHKVAIAGLLDRTVAIAQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADLAKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQALVLPHELALAADDPRVAAHLAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLDMLVRQAGLAFSLWFKQPAPLEIMRAAALAALQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU5</accession>
    <name>A9AZU5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4517"/>
    <dbReference type="EnsemblBacteria" id="ABX07149">
        <property type="protein sequence ID" value="ABX07149"/>
        <property type="gene ID" value="Haur_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4517"/>
    <dbReference type="HOGENOM" id="CLU_1064654_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4572-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28631" checksum="4E797F7F35CD7BFD" modified="2008-01-15" version="1">MTTPQPLVAVTLSRSELLLISALLKAPALMGVQATTADENQRALELLQAEHSLRARNAAAVDENGQLLIVRDLLGVVASCAYPQRSLVVYHTRADGVVLQGFGHVRDDSLVVHTVINPEVHNLAQMPNLDRLIETVFQLSDYAANTPAVNLHVDISREKLVMARQLAEQGQTAQSADTLVRSGVSPTEAELLVRMFRLPSTTTVFVTIQYSGSHAMAREYTLFKNEIGSFLMTQADLEIERYQLKGIDYMGLGGIIYESLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZW3</accession>
    <name>A9AZW3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol-phosphate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.25" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4536"/>
    <dbReference type="EnsemblBacteria" id="ABX07167">
        <property type="protein sequence ID" value="ABX07167"/>
        <property type="gene ID" value="Haur_4536"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4536"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049335_0_0_0"/>
    <dbReference type="OMA" id="NYGWISE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4591-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="28434" checksum="DDF8ECF83B109331" modified="2008-01-15" version="1">MQSPNEAQLMETWARQAGAYALDIFHDYNAAAPRRKADNSWVTEVDETIEQMLRQHIAQAFPDDLIMGEEGGGQASNSGRIWVLDPIDGTGSFVKRLPVWCVSIGLLVDGYPAAGCVYLPVLDECYLAGLTGDATLNGQIINAENPDFLDSQSWMAVPSNAHRRYKISYPGKTRSLGSTAANVCYVASSRACAAILGNASLWDIAGAWPILERAGGKLSTFSGGPFDWQRFYQGASANEPLFAASNNNYANMRAMIDLAQGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY1</accession>
    <name>A9AZY1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1040"/>
    <dbReference type="EnsemblBacteria" id="ABX03688">
        <property type="protein sequence ID" value="ABX03688"/>
        <property type="gene ID" value="Haur_1040"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1040"/>
    <dbReference type="eggNOG" id="ENOG5030T6G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1287367_0_0_0"/>
    <dbReference type="OMA" id="ERIACIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1057-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045507">
        <property type="entry name" value="DUF6483"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20092">
        <property type="entry name" value="DUF6483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="214" mass="24283" checksum="421755173C995652" modified="2008-01-15" version="1">MRDYILRLIEQFGLIWRKIVRLHEAGSIEEAQATINTAYRDLFDTHSHFVDLLPDEDLLKLVQFGGTIDLDRCAVLAALHVAEGQCFQAQGMIDEAYRRFDRALMLYGALVRSSQQIPPEVREAAKAGLHELSNYELEPATLDDAWRVYAAVGDYPNAEDHLWQWLEATEFAEAACSDAQAWYHQLLTRSDASLEQLGLPRQEIEQSLGQLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H6</accession>
    <name>A9B0H6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4563"/>
    <dbReference type="EnsemblBacteria" id="ABX07194">
        <property type="protein sequence ID" value="ABX07194"/>
        <property type="gene ID" value="Haur_4563"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4563"/>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_17_1_0"/>
    <dbReference type="OMA" id="WAHDWIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4618-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731772" evidence="2">
        <location>
            <begin position="20"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="44962" checksum="5690C59F86A3403E" modified="2008-01-15" version="1">MKRILSFLLVSIMMVGLLAACGGETTPTTAPTTAAEPTAAPTTAAEATAVPEATAAATTEATAAPEATTAPATGGDTMAATGDITLWHAYSTGGAEDATLTELIEKAKAAFPDANISVLQVPFDQVFSKFENDVAAAGGPDLLLAPNDSLGDLARKNLLADLDAYKANLTNIAPAGVAGMSVDGKLYGIPESFKAVALYYNKSTIATPPSTTDELLQLVKDGKKLVLNQSAYHNFGFFQAFGASLFTADKACGLVNGGGDALKYLQDLKAAGATFSTDGAQADALFREGQADMIINGPWVLADYQAALSDKLGVAAMPAGPKGPAGPLTGVDGFYVNINSQNVEGAVALAMYLTNTESQKIYTEKAGHVPADVNVVPTDALVLGFSQAASTGYARPQDQELNNFWTPVGDAVTKALDGGEDATKAITDACAAMDTANGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0R5</accession>
    <name>A9B0R5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1137"/>
    <dbReference type="EnsemblBacteria" id="ABX03785">
        <property type="protein sequence ID" value="ABX03785"/>
        <property type="gene ID" value="Haur_1137"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1137"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_949208_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1158-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="178"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="31856" checksum="4B693E017BC45DB0" modified="2008-01-15" version="1">MTTQRILVVGAEAAPKTQFIQQICDTWSSHELELSSMPSSQCIAMDIGHLDYAEQRSVWYGIPASASPVLHDLAQTVTSCIVLIDSINDNAAMLTLADQIQPWITGPVVLLVSQQSNLPDHLRNALDHSSHHIVDSYNMNKPESIQRIMTALGGTLPTASSIQKEYITPNHFDQSAKVQALFEQLAHHSTDLIGAALIAVNGDLLVSTLPQAINAEQLAAIGSPWLRIADKVAASAALGQTEESIIRTEQGLCLIRPIHNHILITLLNPHANLGLYWLNLAEIEQPLTELLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S9</accession>
    <name>A9B0S9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1151"/>
    <dbReference type="EnsemblBacteria" id="ABX03799">
        <property type="protein sequence ID" value="ABX03799"/>
        <property type="gene ID" value="Haur_1151"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1151"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_0"/>
    <dbReference type="OMA" id="FMIVVTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1173-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="91"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="35387" checksum="B03D89ED98CF241F" modified="2008-01-15" version="1">MAISKSQTASAKPTTSRPMLSWKRREQRVAWAFVAPALLLLLIFLIAPFGLAFYLSLTDQRLVPNPNLPTRFVGLKHYLAMWQDATFVRALLNNFLFVAVVVPVQTSFALFLAVLVNQKIKAINFFRTIYFIPVVTIMAIVAVVWTFLYNPDQGIINKFIQTISFGQLGPYRWLEDPKLAFPAIMLMSIWQGVGFQMVIYLAGLQEIPGELYEAAQLDGASAWQQFRFVTLPQLRNTSIFVVISTTIMAFKLFDQVEIMTKGGPNDATVTAMLHIVNSGFRTQKVGYASALSVVFFIIVLLISLGQRIFTRSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0V5</accession>
    <name>A9B0V5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1177</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1177"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03825">
        <property type="protein sequence ID" value="ABX03825"/>
        <property type="gene ID" value="Haur_1177"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1177"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020160_1_0_0"/>
    <dbReference type="OMA" id="DKYCKER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1199-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_20b" evidence="6">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="5">
        <location>
            <begin position="116"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="599" mass="66962" checksum="31131A622DABD5AA" modified="2008-01-15" version="1">MQLLPKPKNLQRAEGSYALPKIWQISLPSGLDQRVTASLAALGEYQMVEQAANLLLTLDSSIVHADGYRLQIAADGVQIVAQTAAGLFYGLQTLRQIQQQSAEQLPYLLIDDAPDFVVRGFMLDISRDKVPTMATLYALIDELASWKINQIQLYIEHTFAYQNHPTVWADASPLTAEEVRALDDFCLERFIELVPNQNCFGHMRRWLTKPAYRDLAECPDGCDTGDPDWGYFEEPFTLAPEHPGSIELVRSMLDELLPNFRTRTLNVGCDETVELGLGASAAAVAERGKGRVYLEFLQKLYHEAHSRGYVMQFWSDIILHYPELVSELPRDAEVLIWGYESHHPFEEQAATIAKAGLPFYVCPGTSSWNTVAGRTTNALENIASAAKHGLNHGAKGFLMTDWGDNGHWQPLVTSYLGLAIGAARAWNALAELDVVALLDTVVFADSNKVLGNLVYQLGDVYRAVPPLLHNTSSLFRILQANPAAIAELNLDRKNLHNADEILLQLRNDLQTIKPQRADGELCQVELAWAIDLLRHAVQRGLWVLDQQPSETASKLQPEIDALIERFQQVWLSRNRPGGLQDSLKHFASLRDSYGEVRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X0</accession>
    <name>A9B0X0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4015 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1192"/>
    <dbReference type="EnsemblBacteria" id="ABX03840">
        <property type="protein sequence ID" value="ABX03840"/>
        <property type="gene ID" value="Haur_1192"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1192"/>
    <dbReference type="eggNOG" id="COG1306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_404795_0_0_0"/>
    <dbReference type="OMA" id="ERWANIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1214-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025275">
        <property type="entry name" value="DUF4015"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13200">
        <property type="entry name" value="DUF4015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735165" description="DUF4015 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4015" evidence="2">
        <location>
            <begin position="353"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="679" mass="73674" checksum="DFACA2FB147A7BAA" modified="2008-01-15" version="1">MYFVSQTKRRLTAGLFGAVALVLAACGSSNPPLTGIVTDSYTQKPVAGVTIQVGEASATSDADGKWTINEWENTNSLLVQASDYSSATLSLADKTPVDEQTPVEVNLTIRPNTISGVVLDQYSQQPVAGVTVKAGTSQATSGADGRYKLTDVAEKAEVVIVATDYTSATATLEKQTSYDVSLRPTSLTGIISDKYSQKPVSGATVSVGSATAQSDAEGRYTVKNIDLDAPVVFSATDYSSQTLELPQAASLDVVLRPSTVRGSVVDSTTGKPLTKGTVIAMVKPFEGADETYPYTGTAVTMARLNADGTYELTDVPENAQIQVLSPGYRKAWTALSEGKFTADLEAEEFVAKAIYITAATGSSKASLSELFDLVDQTEVNAVVIDIKLDIAGDVGGVGYLSQHPLVLAAETSSDYLDMEWIVAEARKRDIYLIGRMAVMRDNRLADAHPEWAAQSKATGGVWEDDGGLKWLDPFNPNVTEYNVGIAKEIAAFGFDEVQFDYIRFPSDGSTSNLVFSKPIDPKNNPEVMYEAIGNVLKRAHGDINGSGAFFSIDVFGYATWRNMWEIGQSLEIMADHTDYVCAMVYPSHYDRNELGFDNADAYPYEIVKDSIEKGQKRMEGKYAVQRPWLQAFTATWLDPVTPYGRTEVRAQMQAVAEVEGTYGWILWNAANYYDPDWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z1</accession>
    <name>A9B0Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2631"/>
    <dbReference type="EnsemblBacteria" id="ABX05269">
        <property type="protein sequence ID" value="ABX05269"/>
        <property type="gene ID" value="Haur_2631"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2631"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_6_0"/>
    <dbReference type="OMA" id="EMTGCRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2659-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26682" checksum="3A72D5F5DC98A643" modified="2008-01-15" version="1">MPGRPLVLFDIYGTLVDVHTDEHQPALWQHLAQWLRYRGLACSADSLHKRYFAAMQANLPAHEAYPEWQTEAVWAELLAEFGLDPAEAVSITQLLRVLSIKHLRLFPDTKEALRILRQHYCLGIVSDAQRVIALAELAELEILEYFDPIVISSDYAYRKPDPRLFAHALAQVETPANHPWYIGDNLFRDVQGAQLAGLRAAWVKRPQATTEASQHTPDLIVPDLMTFALHLIANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B107</accession>
    <name>A9B107_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitin-binding domain 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2647"/>
    <dbReference type="CAZy" id="AA10">
        <property type="family name" value="Auxiliary Activities 10"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05285">
        <property type="protein sequence ID" value="ABX05285"/>
        <property type="gene ID" value="Haur_2647"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2647"/>
    <dbReference type="eggNOG" id="COG3397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063855_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2677-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734476" evidence="3">
        <location>
            <begin position="30"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="260"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="32844" checksum="511DDA39AE0DA2F7" modified="2008-01-15" version="1">MVQRRIFSLTVGCWSALLLVLAISSQVNAHGAMQTPVSRTYACFLEGPETPDTAACRAAIDIGGTQPLYDWNEVNIGNAAGQHRSLIPDGKLCSAGRAKYAGFDLARADWPATPLTSGSSMSFLYRATAPHPGSFEFYITRDGYSPTQALKWSDLEATPFLKVTNPQLVNGSYVINARIPNNKTGRHLIYSIWQRSDSAEAFYTCSDVTFGGTNPTSVPTATPRPSAVPTATVPPTGTPIATATPRPTNVPTATPTNPTTQAWQPYTSYATGAGVAYAGNTYICRQGHTSLPGWEPSAVPALWQLIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B119</accession>
    <name>RS21_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsU</name>
        <name type="ordered locus">Haur_2659</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B119"/>
    <dbReference type="SMR" id="A9B119"/>
    <dbReference type="STRING" id="316274.Haur_2659"/>
    <dbReference type="EnsemblBacteria" id="ABX05297">
        <property type="protein sequence ID" value="ABX05297"/>
        <property type="gene ID" value="Haur_2659"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2659"/>
    <dbReference type="eggNOG" id="COG0828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159258_1_2_0"/>
    <dbReference type="OMA" id="FKRSCQK"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000120629" description="30S ribosomal protein S21">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="65" mass="7568" checksum="C2D0701C47A80EF7" modified="2008-01-15" version="1">MASISVDSNESIDKALRRFNKAVQADGILTEARRREHYEKPSVKRKRKEAARLRKLQKMAREANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E2</accession>
    <name>A9B1E2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4698"/>
    <dbReference type="EnsemblBacteria" id="ABX07329">
        <property type="protein sequence ID" value="ABX07329"/>
        <property type="gene ID" value="Haur_4698"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4698"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061564_0_0_0"/>
    <dbReference type="OMA" id="LRRMRTY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4755-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="265"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="38501" checksum="284D503182B15620" modified="2008-01-15" version="1">MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALAIGAAIMIFLVALLLLRRNYFKLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMALASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKPMDKNYGGIIGGYTAVALVLGMVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLLEANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLDVTGVPLVDVHMAGELAAVIAATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1H9</accession>
    <name>A9B1H9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1216"/>
    <dbReference type="EnsemblBacteria" id="ABX03864">
        <property type="protein sequence ID" value="ABX03864"/>
        <property type="gene ID" value="Haur_1216"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1216"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_923683_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1238-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="301" mass="33919" checksum="9B3536E1F76EBA52" modified="2008-01-15" version="1">MTTDGFHDGSAIELTPAASFTIDELVAIYNQTRIDYIVPMPMNSQRLAEYIRLYDVNLDASFVAKADGDILGLAMLGVRRDHAWVTRLGVLPNRRKGGIGRALMIAMVEAARQHWLKYVQLEVILNNTPAHKLFLALGFEETNQLLVMRRPPGPVKQPAVGSIEWLDWSQLQRLVRQQPQGVPWTNQADSYDHMAMVEGCRINLADGGRGWCIFRRQPLVLSHIRLHTEAGDPNAVGSALLAHVHQRHSRLDTQAENIRCDDPHLVAYEQHGYIEAFQRIEMLLNLVANERVNKNPPQSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L8</accession>
    <name>A9B1L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cell division inhibitor minD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1255"/>
    <dbReference type="EnsemblBacteria" id="ABX03903">
        <property type="protein sequence ID" value="ABX03903"/>
        <property type="gene ID" value="Haur_1255"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1255"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096711_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1277-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="254" mass="27938" checksum="DFD3D6CFB09BCA34" modified="2008-01-15" version="1">MPKIVSIHSFRPGTGKSQLTANIATILAAAGQRVAIIDSDVHSPSIQWLFGLPEGAITHSLNDFLWGKCGIESTAVNLNPTVRHPLKGQVYLVPFATRNSTIDYDISLLSDSFELLINTLRLDVLLIDTQPGVQFAALPSIAFSDIQVLVLQLREQDLQGTGVVIDISEQLGISEMVLIVNQIPEHYNLREVQQKIEQIYQRPVLAALPYDELLADYNQASLLLERTSSNIFVVEHPDHPISLLLTNVAATLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S5</accession>
    <name>A9B1S5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2729"/>
    <dbReference type="EnsemblBacteria" id="ABX05367">
        <property type="protein sequence ID" value="ABX05367"/>
        <property type="gene ID" value="Haur_2729"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2729"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_412666_0_0_0"/>
    <dbReference type="OMA" id="WIDGSVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2760-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="471"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="665" mass="72533" checksum="826CF8CEA3E3F6D9" modified="2008-01-15" version="1">MRVLDAPTNQARPTPQPRLTPAMSFGLATLGVFVGVGWLWLAPHWLALLITLGSLSLLLGQAWASIQRTERERTVLAQAHSALDSEYNSIQADYATLERAYEDLQQSYQRLQRRIDERTAERDQSTNQLQTLLDDTRSYVAQLTALNEVSVALNATLDRDEVLACILRQLERVVTFDSASVQQLEDDELQVIAARGMNNEVYDMRISVPDNELARKVVGSPAPVVLGDVRKDPSFVMQPGPIRSWIGVALRVGERTVGILTVDSHRENAYTADDGHLVANFANQAALALHNSHLFAAAERRATEMALLLEMTRTVGSTLHLPEVLLRAAAAIGEALHAEDVLVLLLDEQGERLTPQAGAMGDHNYLRMRWASPTSLSNEPTLAKVIKQGCARVIHAVSPTIPYQTLLALPLSIKEQVLGVVLVATPDRDAPFGPQQLVLAEGLATSAAIAIEQARLYDQARRAAQAEERSRLARELHDSVTQTLFSMTLTAEAARAQVERNPVRAATQIDRLKAAAHQSLGEMRELLLQLRPTPLQEHGIIKSLRDHIASLNAQEVAINLECEGEDSVLSPANAAGLYRIAQEAIANALRHAQATNVRVSFSFASKSTTLMVKDNGCGFDPDLLERSGRHLGLTSMAERAGELGGTLDVQSVVGEGTCLTVHLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B239</accession>
    <name>A9B239_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4758"/>
    <dbReference type="EnsemblBacteria" id="ABX07389">
        <property type="protein sequence ID" value="ABX07389"/>
        <property type="gene ID" value="Haur_4758"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4758"/>
    <dbReference type="HOGENOM" id="CLU_1336003_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4816-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="24238" checksum="6A9B2F5A2C5298E9" modified="2008-01-15" version="1">MLLSNERTSMQSSLIKQRLRVPYYRWQIAAVFLYFILVVFNFWIPTKTSVPLITYSNMIIYPLLLIQFSMNVISYLDLSARGLVMRRGWQRFEVNWEHIEAFGIGTIGRRRYLPYIILHQPIKGLPSVKLKELTPEQRQRTLTLEGWDNPEIIAKTLHASLASTTDQWQVTPDFSKSLKFFYSYQKMIAWATLVVILIFVYLFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B252</accession>
    <name>A9B252_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4771"/>
    <dbReference type="EnsemblBacteria" id="ABX07402">
        <property type="protein sequence ID" value="ABX07402"/>
        <property type="gene ID" value="Haur_4771"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4771"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_2_0_0"/>
    <dbReference type="OMA" id="INIFARQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4829-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="109"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="25521" checksum="A4A7305271578A93" modified="2008-01-15" version="1">MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILANMVNRVSKELALSREQDQKHLAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVVLMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVSLIDTQVANVLIRAAQSCNLLGAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B296</accession>
    <name>A9B296_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4816"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07446">
        <property type="protein sequence ID" value="ABX07446"/>
        <property type="gene ID" value="Haur_4816"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4816"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065962_0_0_0"/>
    <dbReference type="OMA" id="YTELWAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4875-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="29068" checksum="80E568FA9972E223" modified="2008-01-15" version="1">MLLSVAMIARDEERHIGAALASIGDLADEIVVLLDPRTRDRTAEICLQAGARVVEAIFESFPAQRNRALAECQGQWVLFLDADERITRNLQHEIRQLLQGQPEYAGYWIPRFNRYWGRALRGGGWYPDHQLRLLQRSKAQYETSRLVHELVILDGLKGRLTQHLEHINIESWAELREKQQRYAQAEAATLYRNGVRVKPQNYILQPWRAIWRRYITWGGYRDGLLGMLLALVMGWYEFKMYLALAKHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U9</accession>
    <name>A9B2U9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06012">
        <property type="protein sequence ID" value="ABX06012"/>
        <property type="gene ID" value="Haur_3376"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3376"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1025913_0_0_0"/>
    <dbReference type="OMA" id="WILIRAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3413-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045276">
        <property type="entry name" value="YbiO_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30460">
        <property type="entry name" value="PTHR30460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="30154" checksum="807BBECB8A22A69A" modified="2008-01-15" version="1">MFDWIQPYLPPTNSASYYILRGTLTFLVVAVAARAISIIIRRAFLSNAQLLRHNLSERRRKTLRSLVSSLTNGLAILISLFLIMGMFIQPSALFTFLGLFSAGLGFSARPYVSDFLGGITLLFEDQFALGDKVEIGDRQVVGCVERISLRMTYIRGESGELWLVPNGDIRTIRNFTRGKWSPASIKLTVPTTKLDETMIVLHQIISDPGDDVIETPEIISEDGEIGAVTTTITLKVKARYSMAPAVRERLITQLQAALTEHHVLAADENRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L6</accession>
    <name>A9B3L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2950"/>
    <dbReference type="EnsemblBacteria" id="ABX05588">
        <property type="protein sequence ID" value="ABX05588"/>
        <property type="gene ID" value="Haur_2950"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2950"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043035_2_0_0"/>
    <dbReference type="OMA" id="FEYWAHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2982-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="46740" checksum="86E1B420C007EDF1" modified="2008-01-15" version="1">MTRTISLDQARAIAIAAQGLDRRPNTVDQTTLQQTIQRMQIVQIDTINVVARAPYFVLWSRLGDYDPAWFEQLQYPAGQLFEYWAHAASFLPIELFPLLRPAMLRYIHDWHRSRRWLEENKAVADGVLAMIRERGPLRSADFEAPADHAGGGWWNWKPAKSALDILWGMGELMIVRREKFQRVYELTERVVPDWDDRDVLSFEAAAEQLSERGLRAMGIATERHLPDYFRQRRPGIKERLQTWAAEGKAIEVHVEGWKTPAYIHHDQRHLLEQTPTPSLTTMLSPFDNLIWDRQRTLDFWQFDYRLECYTPAPKRRYGYFTLPILWKDRVVGRIDAKAERSAGIFRVHALHLEPNIELSEALYDDLAVMLRDCANWHRTPTISITMSDPPQVADEVQARVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N4</accession>
    <name>A9B3N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2968</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2968"/>
    <dbReference type="EnsemblBacteria" id="ABX05606">
        <property type="protein sequence ID" value="ABX05606"/>
        <property type="gene ID" value="Haur_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2968"/>
    <dbReference type="eggNOG" id="COG0699">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014646_1_0_0"/>
    <dbReference type="OMA" id="HFWEDVQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3000-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="60"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="552"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="583" mass="65753" checksum="667516A2585CE044" modified="2008-01-15" version="1">MAHVGAQSILGEREAELRAAEQSLFDRLHHALEQFGADVTATDAARLREATEQLAELFLIVVAGEFNAGKSSFINALLGDRVLPEGVTPTTDRINILRFGEQPDSQLLEDFLLLRTHPAPLLGDLNIVDTPGTNAIIRRHEELTKRFVPRSDLVLFITSADRPFTESERTFLEHIREWGKKIVLVINKIDILDEKGRGEVIEFVRSNATTLLGSTPMIFAVSARSALRARENDDPKLWAESGFNAMEEYLLRTLDQGERVRLKLLNPLGVGQKLATTYRTASDERLHTLSEDIKAINNIEGQIQVYKADMQRDFTPRIAQLENLIHEFEQRGHSFFDEQIRLGRARDLIKKDLLEQRFRDQVVGDLDAETDRITQQIIDWLIERNLKLWQDVNAYIDRRQISRHKDEMVGNVGQNFNYNRQSLIDSVGRSTSQIVQSYNRDAEAKQLAMDLQGTIATTALTGVGAVGFGALFVILAHGALLDFTGISLSVLAVAGGAYLIPAKRAQAKREFHKKVSELRDKIVRSLSKQVYAEIDQSIERVTETVAPYTRFVKFQNEQLQHARNELASVEQALGRLRGEIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q2</accession>
    <name>A9B3Q2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2986"/>
    <dbReference type="EnsemblBacteria" id="ABX05624">
        <property type="protein sequence ID" value="ABX05624"/>
        <property type="gene ID" value="Haur_2986"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2986"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066001_1_0_0"/>
    <dbReference type="OMA" id="ALMMTIQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3018-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="219"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="341" mass="37417" checksum="FDDFA8328C016C62" modified="2008-01-15" version="1">MDLSIVRERLLQVVISLTVIIGVFGLAFLGLGTVFSNTVLLIVSSIMGVNALICGFMWYGYDNYSNTTVVWSIGASLLFSTIILALIQPILSTGYMFTPLIVAITGLQYISNEQKGTIVVTSISSSIVAFFAGLFSPFKEYQVLSWFVYLNAAVIIGIFIIIGFLLWQFNQRLISMIDSITESNAALALKNEVLLSTNGDLKKQIELEKQLREQIADLEVPITELAHDVIYAPIVGHLDDQRIDTFREALLKRVHEQRARAVVLDVTSIAHIDTYGCGLLTQTIQTVKLLGTQVVLCGISASMAMILTNLGISFGEDLRVARSPSDAMRMLGVGEKQLMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B403</accession>
    <name>A9B403_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsA</name>
        <name evidence="8" type="ordered locus">Haur_3503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3503"/>
    <dbReference type="EnsemblBacteria" id="ABX06139">
        <property type="protein sequence ID" value="ABX06139"/>
        <property type="gene ID" value="Haur_3503"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3503"/>
    <dbReference type="eggNOG" id="COG0849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037850_3_2_0"/>
    <dbReference type="OMA" id="DGIIRHT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="415" mass="44313" checksum="39AE1404ACB6B754" modified="2008-01-15" version="1">MNRTIVGIDVGTTKICTLVAEVHDTGKVNILGVGLTPSKGLDRGVVVNIDEAVSAIATSVEKAERLSGYRIGTAFVGIAGRHISSVNSRGVVAISRPDHEISRTDVARAVEAAQAIAIPTQREVIHVIPRAYIVDGHEGIRDPVGMAGYRLEVETHIVTGEVMAIQNLIKSVERAGVGIDDLVLQPLASGEAVLSEEDKSRGVVLVDIGGGTTDIAIFIGGGIWHTVVLPIGGAHFTNDLVYVLHTPHNTAEYLKLRYGKVTDIDSHDPADDLIDTDGFSPGEHQQVSRVELNEILQARAEQLIDMIGNEIRRSGYEGLLPAGIVLTGGSAQLPGLDEMARQLLGMPVRIGIPTNLTGLAEAIDAPPYATAVGLVRWGLRHGMGSVGGHAASQPATTNWKQTYDRFKMWLREFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B451</accession>
    <name>A9B451_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tail Collar domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4954"/>
    <dbReference type="EnsemblBacteria" id="ABX07584">
        <property type="protein sequence ID" value="ABX07584"/>
        <property type="gene ID" value="Haur_4954"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4954"/>
    <dbReference type="eggNOG" id="COG4675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087872_0_0_0"/>
    <dbReference type="OMA" id="QPYLAMN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5017-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="2">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="18325" checksum="82866A9981176724" modified="2008-01-15" version="1">MADPFVAEIRIVGFNFAPRGWAFCDGQLLPISQNTALFSLLGTTYGGNGKSNFALPDFQGRSPMHQGQGPGLSLRDLGETGGSETVTLLQSEIPSHNHIFNYVGIDGNNADPTNNLFGGSESTDAFRNAPDTTLSPQELSLTGGDQPHNNMQPYLTLNFIIALQGVFPPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B493</accession>
    <name>A9B493_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phage shock protein C, PspC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4996"/>
    <dbReference type="EnsemblBacteria" id="ABX07626">
        <property type="protein sequence ID" value="ABX07626"/>
        <property type="gene ID" value="Haur_4996"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4996"/>
    <dbReference type="eggNOG" id="COG1983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2329897_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5059-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10632" checksum="4441F178E9559C0E" modified="2008-01-15" version="1">MSYQSRQLVRPNEGRVLAGVCAGIARYFGIDPLIVRIALVFFGLFVGSGILAYLIGWALIPDSTGKRAGTPIIIALVIFGVPFICYLITLPFQLLFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B9</accession>
    <name>A9B4B9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0024"/>
    <dbReference type="EnsemblBacteria" id="ABX02676">
        <property type="protein sequence ID" value="ABX02676"/>
        <property type="gene ID" value="Haur_0024"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0024"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_5_0"/>
    <dbReference type="OMA" id="CNEKCEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-24-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="4"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="32911" checksum="59D8DB75EC0EFC0B" modified="2008-01-15" version="1">MYTNAHTHLELSALAEVCPTGQEFGSWLQTMLARRMQLDNATLERGIHKAIEQLQQNQTTTVGDISATRLSIEPLLSSGLAGVVYLEVLGFDPTVALERLSAAQREIDTWRKRETAMKIGLSIHAPYSCAPSLFEAAARWCRAEAVPWAIHIAESPAEVAFLQQGIGSLRELNRRITPHIEWQAPQCSPIAYLERLGVLEAQPVLVHAVQVDAHDLALIAQYDCAVVHCPRSNHNLLCGRMPLEQMLAQGIRVGLGTDSLTSAQSLDMRDEISFAQQLHAYKVAPNIIEQLATQPSILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G4</accession>
    <name>A9B4G4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">polA</name>
        <name evidence="15" type="ordered locus">Haur_0069</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0069"/>
    <dbReference type="EnsemblBacteria" id="ABX02721">
        <property type="protein sequence ID" value="ABX02721"/>
        <property type="gene ID" value="Haur_0069"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0069"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_0_0_0"/>
    <dbReference type="OMA" id="NRPPMPD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-70-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="3"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="333"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="702"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX02721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="953" mass="105128" checksum="98B7C0D9D9A997E3" modified="2008-01-15" version="1">MQQRPTLVLVDGHALAFRAFFALRDTGMSVRATGEPTYAVQGFLSILLNLLRERQPEYVAVSFDIGRTFRDDLYPDYKAGRAETPADFHPQLERIKQIINALNIPIYTAENYEADDVIGTLCRQAEAQGVDTLIITGDTDTLQLVNDYTKVLLANPYGKGNVSLYDEAQVRERYKGLAPNQLADLRGLKGDTSDNIPGVKGIGEAGAISMLNEWGSVENIYANLDKVANRYRSKLDGQQEAARFSTHLATIVTNAPVTLDLEATKVHDYDRDTVLALFSQLEFRKLVDKLPLSSQVSAVQVVAIPQTTNPNQLTMFDDATPPSAEPIAQSGDYQAVTTSEQLAELVRILTAAERLIFDVETNSLNLFSPVPAKVVGIALTHTAGCGWYIPLGHRSGQQLPIAEVVAALQPLFSDPQKAVVAHNGKFDMSALSLIGLDVPHLSFDTAIAAALLGKRQSLKDLAFAELRDADDRPIEMTRIETLIGTGKKQITMDQVAIEQVTPYASADVDMTARLLALFMPQLGAIPAVREVFEQIEMPLSPVLMRMEACGIGLDRAQLVQQGQVLGQSLREIEQHIADFVGEPLNINSRFDLNDLLFIRLKLPTANLKRLAGTTRSGGAVYSVNAETLEDLQTHDQSGIVAMILRYRRLSKLKSTYVDALIELINQQTGRVHTQYRQIGAETGRLSSDSPNLQNIPVRSEEGREIRRAFVARPGHVLMTADYSQIELRVLAHITADPALVEVFKTGQDIHAATAARLFDIPMDEVSKNQRRIAKMTVFGIIYGISSFGLAARTALSRTEAQQMINGLFAQYPGLKSYIERTLERVKAVGYVETLFGRRRYFRELQDGGVTGPRRSAFEREATNAGIQGTAADLIKLAMIRLEQALIAGGYQAKMLLQVHDELVLEVPEDERDAVAQLVCDTMTQVYPDLAVPLEVNVETGLNWDQLQRWHAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I6</accession>
    <name>A9B4I6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1507"/>
    <dbReference type="EnsemblBacteria" id="ABX04151">
        <property type="protein sequence ID" value="ABX04151"/>
        <property type="gene ID" value="Haur_1507"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1507"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056890_1_1_0"/>
    <dbReference type="OMA" id="NASLWED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1529-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="161"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="34421" checksum="EC123FB2E89227E0" modified="2008-01-15" version="1">MHLIQRAFQPEHDQSAMLALASANPDQHMRSIDLPYRLSSWTLDDPANIAIWQTDTGQIVGWAALQVPFWMIDLVWHPDTPLSLYRAMLEWADQRAQSLIGTKHARPAWFVSVFEHQHELREVLTSQGFADQSAVEQDPWSKYLFRRGNQDPSPVSLSTGISIRTLAGMTEIAAYTSLHRAVFESTSMTEGWRANTLKQPSYRAELDLVAVDQTGALAGFCIGWFNQQGFGGQPSGQIEPLGVRADLRQQGVAQALLAENFRRMLALGAEQIFVETDNYRGAAFNLYETVGFAIHAHALVYRKDYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J7</accession>
    <name>A9B4J7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1518"/>
    <dbReference type="CAZy" id="GH55">
        <property type="family name" value="Glycoside Hydrolase Family 55"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04162">
        <property type="protein sequence ID" value="ABX04162"/>
        <property type="gene ID" value="Haur_1518"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1518"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013797_0_0_0"/>
    <dbReference type="OMA" id="VQHHGFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1542-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735258" evidence="1">
        <location>
            <begin position="33"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="734" mass="78458" checksum="5299AAA1527358D4" modified="2008-01-15" version="1">MDTHFWRKLAAVGLACSILFTFITTAPQAAFAAAPLGQTIWLRAISSGKYVSADANRGANSPLVADRDTANGWEQFQVVDAGNGYVGLRALATGKFVSADQNFANTPLVADRNTISGWEQFQWVDVTAGQVQLRSIGNNNFVSSDLNLGTHAPLVANRPTASGWETFNWGVVGTNPTPNPTTPPGTTPDFGPNVLMFDPSMSTASIQAQINNVYGIQQNSQFGSARYTLMFKPGTYNGLNIPVGFYTQLLGVGASPDSVNINGNVYSNAYLGNDNATCNFWRGAEGLAITPSNGTMQWAVSQAVPFRRMHIRGNMKLNQNNGWSSGGWMSDVLVDGNVNSGTQQQWISRNTQWGSWTGSNWNMVFVGVTNPPAGSWPNPPYTKIAQTPIVREKPFVTVDAAGNWGVRVPSLRTNSTGITWAGGSTPGTTIAMSQFFIAKPSDSAATINAQLAAGKHLLFTPGIYALNDTIRVNNPNTVVLGLGFATLRPTTGLAAMTVADVDGVTIAGVLFDAGLINSPVLLEVGPNGSNASHAANPIVLHDVIFRVGGAAAGKASTSFRINSHDTIVDHTWVWRADHGDGVAWNSNTGANGVIVNGNNVTIYGLFVEHYQQYQVLWQGNGGRVYFYQSEIPYDPPTQDSWRSAAGVNGWASYKVADNVTSHEAWGLGIYSVFTNPNIWLARAIEAPNNLNVRFHNMISVAIGANGGISNVINNTGGSTQPNVTYTPKVTNYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N4</accession>
    <name>A9B4N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1556"/>
    <dbReference type="EnsemblBacteria" id="ABX04199">
        <property type="protein sequence ID" value="ABX04199"/>
        <property type="gene ID" value="Haur_1556"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1556"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041665_0_0_0"/>
    <dbReference type="OMA" id="TYCTNIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1580-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="407" mass="45527" checksum="9921134255AE25AA" modified="2008-01-15" version="1">MQLNQAPQLDLTYCTNIHPANGWPAVLAGLQQHVLDLKQRLAPNQAFGIGLRLSGQESHQLLEPTALADFQAWLTEHNLYVFTLNGFPYHPFHQQPVKDQVHAPDWREPERVAYTLRLIEILAALLPKGMVGSISTSPLSYKPWFADLSAVPWALLNRHVLQVVAALVQLERQRGIVIQLAFEPEPDGLLETSSELIGYVEQLLDVGAVELAAQLDCSLREAQNAIRRHVGACLDTCHCAVAYEAPRHVIAAYQTAGISIAKVQLSSALQVMLDDDRQAVAAALAPFSEAIYLHQVIQRNHDGSLQQYRDLPQALEKIDDPAACEWRIHFHVPIFTASFGLLNATQPALLESLQALLESLQALNEQPYSQHLEIETYTWDVLPSQLKLDLTESIAREYAWVLHELKR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R2</accession>
    <name>NRDR_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrdR</name>
        <name type="ordered locus">Haur_1584</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B4R2"/>
    <dbReference type="SMR" id="A9B4R2"/>
    <dbReference type="STRING" id="316274.Haur_1584"/>
    <dbReference type="EnsemblBacteria" id="ABX04227">
        <property type="protein sequence ID" value="ABX04227"/>
        <property type="gene ID" value="Haur_1584"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1584"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108412_0_0_0"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_1000124514" description="Transcriptional repressor NrdR">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-cone" evidence="1">
        <location>
            <begin position="48"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <sequence length="150" mass="17383" checksum="D6579D3D2E53B8C3" modified="2008-01-15" version="1">MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPYDREKLLRGLRVAAYKRPISADVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDEVAYIRFASVYRSFSDLGKLREAVEELMEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S3</accession>
    <name>A9B4S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3008"/>
    <dbReference type="EnsemblBacteria" id="ABX05646">
        <property type="protein sequence ID" value="ABX05646"/>
        <property type="gene ID" value="Haur_3008"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3008"/>
    <dbReference type="eggNOG" id="ENOG5032YUA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116209_0_0_0"/>
    <dbReference type="OMA" id="GGWSWWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3040-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021454">
        <property type="entry name" value="DUF3105"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11303">
        <property type="entry name" value="DUF3105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="204" mass="22489" checksum="A23AA50134EE310A" modified="2008-01-15" version="1">MSQPRRGRRQVGQKSRLPLFFGIGAVLLVIVVIAVVVLNGGEDKVDKVTVAEGTTAPSTTGVVQELPDEGQQHVADGEKVAYKQNPPTSGSHWAGPAQWGLYQTNPPEDERIVHNMEHGGVIIWFKPSAVSAAENDQLVKLFTALSAEQYRTILVSRENMDTKIAMTAWNHRQLLDSVDETAIRAFFDEFILKGPECVNLRCPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B507</accession>
    <name>A9B507_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3092"/>
    <dbReference type="EnsemblBacteria" id="ABX05730">
        <property type="protein sequence ID" value="ABX05730"/>
        <property type="gene ID" value="Haur_3092"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3092"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_8_0"/>
    <dbReference type="OMA" id="REQRVDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3124-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="128" mass="14211" checksum="BAE888CB712D20B3" modified="2008-01-15" version="1">MTNAVRNPAIILVEDEPDILIILHRIMRDLTGGYDIVTVNSAQDALGVLTERSCPLLITDHNMPGMTGTQLTQVVKQDYVDTKVIIITAYATPEVERTARTAGVDYFLTKPFSLDRLEQIIKEVLGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B561</accession>
    <name>A9B561_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3562"/>
    <dbReference type="EnsemblBacteria" id="ABX06198">
        <property type="protein sequence ID" value="ABX06198"/>
        <property type="gene ID" value="Haur_3562"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3562"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1784221_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3599-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="15721" checksum="68023614854E7B43" modified="2008-01-15" version="1">MSSPIVQIDYAVVDTIIQRFQKLYDQSQTIQASLCQTMASLQAGQWQGSAANACFQEFDHVVKPAFQRLLHSLQGSVETTKAIRKIMADAEAEAAALFRGDVGAMAVGGNGAMFVQFVDGEIRSKSTPTPTPPSDKPLLPPFFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B571</accession>
    <name>A9B571_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3572"/>
    <dbReference type="EnsemblBacteria" id="ABX06208">
        <property type="protein sequence ID" value="ABX06208"/>
        <property type="gene ID" value="Haur_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3572"/>
    <dbReference type="eggNOG" id="COG1534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095994_2_1_0"/>
    <dbReference type="OMA" id="ERIEICN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3609-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017924">
        <property type="entry name" value="RNA-binding_YhbY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00253">
        <property type="entry name" value="RNA_bind_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="3">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="11134" checksum="584A58682C972DBA" modified="2008-01-15" version="1">MLTLNSNQRQYLRRLAHDLKPVVQIGKQGLSSTVVAAVAAALDAHELIKVKFGEFKEERRELTDQLVADTEATLVALVGNVAILYRPSRLDDKQVIVLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A1</accession>
    <name>A9B5A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3602"/>
    <dbReference type="EnsemblBacteria" id="ABX06238">
        <property type="protein sequence ID" value="ABX06238"/>
        <property type="gene ID" value="Haur_3602"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3602"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_4_0"/>
    <dbReference type="OMA" id="ESYLMHD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3641-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="28687" checksum="4D647F9586B26F7B" modified="2008-01-15" version="1">MPPIDVRGHSLMYDDGGDGEVVLCIHGFPFNRSMWDEARLALASRYRVLSPDLRGFGESSGSESWTLDDQANDLIELLDQLGIDRVAVLGLSMGGYIALNLARRYPERLWAMVLIDTKATSDNYDAKQNRLKTAETALREGAAPIAAQMLPKLLSPANADDQRLIERLNSMMLTTNPKTIASAAHAMASRPDSTPYLSTMALPSMVIVGNDDQITTPNDAHAMVAALPHASLVTIPDAGHMSVLEQPEIAYGAIRVFLEQAQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B2</accession>
    <name>A9B5B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0085"/>
    <dbReference type="EnsemblBacteria" id="ABX02737">
        <property type="protein sequence ID" value="ABX02737"/>
        <property type="gene ID" value="Haur_0085"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0085"/>
    <dbReference type="eggNOG" id="ENOG5031R3M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087830_0_0_0"/>
    <dbReference type="OMA" id="GPKDFSQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-86-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="24109" checksum="A64867CAF051B398" modified="2008-01-15" version="1">MPSTKYYAYLQTFQVKRLERDYKYLLAEPQYHGLAQFFLEDMYGPYDFHARDTQARRLHQFIHLAPGLSIEDIEVTLDLLNLTVRLDQQVADWLEHNNFTIPFTEAQYEEAYYRVNSFEPRVRQIELINESLRRVHRLSKISLLGAALNNTKTFAKLMGMGELHRFLRRGYHALLPVQDLKPFLTEVTHTELDRLKRIYRLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5G0</accession>
    <name>A9B5G0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isocitrate/isopropylmalate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0133"/>
    <dbReference type="EnsemblBacteria" id="ABX02785">
        <property type="protein sequence ID" value="ABX02785"/>
        <property type="gene ID" value="Haur_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0133"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_0"/>
    <dbReference type="OMA" id="DVRYEPQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-136-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="1">
        <location>
            <begin position="5"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="38875" checksum="3531F850F5E44449" modified="2008-01-15" version="1">MSKPTIVVLEGDQTGQELLEESLRVLDPAVTGVDIELKRYDLSLESRRATNNQIVLEAAQAMKEAGFGLKAATITPEKAGDVGSPNAILREQINGTVIVRTGRRIPGVRPVGGAYAPISVIRMAVDDAYGAKEWREGEGDNEVAYRTEKITRGTCRAVSEYAFMHARRMKAKVFGGPKYTVSPIYEGMLKEEMDAAAKRYADVRYEPQLIDATYALLLTNSGDPMVIPALNRDGDCLSDLVLQMFGTIAGAESLLLAFDKDFKVNVVMAEAPHGTAPSLEGKNVANPMAMILASAALLDYIDTPQANMAARAISEATLEAVYDGVRTADLGGHTTTSDFTDEVIRRVKTKMEVWPSLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P6</accession>
    <name>A9B5P6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1636</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1636"/>
    <dbReference type="EnsemblBacteria" id="ABX04279">
        <property type="protein sequence ID" value="ABX04279"/>
        <property type="gene ID" value="Haur_1636"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1636"/>
    <dbReference type="eggNOG" id="COG1514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081251_3_2_0"/>
    <dbReference type="OMA" id="HITLRFL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1660-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="22056" checksum="394F6A49BBC90D93" modified="2008-01-15" version="1">MSEQWRCFMALDLPEPIQAQLLAIQAELQQLGLPIRWSKPENLHLTLQFLGNLAVELLPDLQTKLNHALTQQTAPTLNCNTWGYFPNASQPQVVWAGFEQWPNDLLQLQQAVVGCSSHIGIIAETRPWHPHITLGYSKERLTKHQIEQLSSQLQASQWPATPAIYPTCQLIRSISQPQASSYQTLVTWQLNQAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q7</accession>
    <name>A9B5Q7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04290">
        <property type="protein sequence ID" value="ABX04290"/>
        <property type="gene ID" value="Haur_1647"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1647"/>
    <dbReference type="HOGENOM" id="CLU_2130036_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1671-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12804" checksum="86FFB0EE3D4217FB" modified="2008-01-15" version="1">MVVLITESNELRQRFIDRFEVLAMPLMVTTPRMINACFQQFVPERIFVDASICTPGLIRWLDQCDDAEIILIANSRGSIRHAPRGAIMYIHPSLEPEDIVPLLPLRQDANSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y5</accession>
    <name>A9B5Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3141"/>
    <dbReference type="EnsemblBacteria" id="ABX05778">
        <property type="protein sequence ID" value="ABX05778"/>
        <property type="gene ID" value="Haur_3141"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3141"/>
    <dbReference type="eggNOG" id="ENOG5033WSU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1010809_0_0_0"/>
    <dbReference type="OMA" id="RRQEYRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3173-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732500" evidence="1">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="28847" checksum="B5C9113100AD2A74" modified="2008-01-15" version="1">MRSGIWRSCCLLLLVFLTGCGSSLTIYDITSNPANYNGQEITVEGVYLWKPGNPGLSVLAKAVSTRNDGTDAQPVDSLVWLDEFPAEASANLHRPIDSVYGAVRVKGKFETGAFGPDGSFTSRLVVQSAEAIERVERVEYPAPTEAQPNQVSIYELEKNPSAYNGQTVTTRGMYYWTQASSGLLTTGVQSEKPLGDNVASGVNPQPMGTPISMEGFPPDLSSQLNVGPGNGFVWGLVEVTGTFQTGGQFGLEGRHGSQLILDPASVKPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B653</accession>
    <name>A9B653_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06264">
        <property type="protein sequence ID" value="ABX06264"/>
        <property type="gene ID" value="Haur_3628"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3628"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841377_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3667-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="36573" checksum="8C2B8A558FDF0E81" modified="2008-01-15" version="1">MRYRLLIGLIVVVILAVSCGRTQISNDERSAQSATLQTATSPIEPSHTQAPLIIYEPIVNTPTREYRLFTQKECGTYTEEPGPASFTINCWHGLVNGNDFFVDANGVRHKPANYAVLAGFLTIYKNGEFINHFHFPVELGGLTIVREMLPSLVISVGGHFESLFNLETYQWTDLEGMPIVLNPTTTIWPTISIPTIAPRIEILGVSLLDGDTNQPIPGFDPMPNPATIILDSLPTKHFNLQVHTNPATIGHVAFLFDGDTPYRIDDTPPYTFVEINERWSPQVGIYQLAVVASPGDSVEWQRNSTVIEMIVSKHPITPTIETKATPAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B694</accession>
    <name>A9B694_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06305">
        <property type="protein sequence ID" value="ABX06305"/>
        <property type="gene ID" value="Haur_3669"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3669"/>
    <dbReference type="eggNOG" id="ENOG5033Z6N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099782_0_0_0"/>
    <dbReference type="OMA" id="IGIERWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3708-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17819" checksum="C2E4643AD8661E6F" modified="2008-01-15" version="1">MRNLILKVVSYLFFIRPSKQRSYGDYEKLLTESGTTIEQRANQAADLPENRKQLRHIVGIERWGVQRLKVCFGEPFNRDEYNGYAPAEDRSWPQLQADFKATRQETIALAKRFALEQPASDVVEHNDFGAWNARTWLQYLYSHGLNEAKRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B695</accession>
    <name>A9B695_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3670"/>
    <dbReference type="EnsemblBacteria" id="ABX06306">
        <property type="protein sequence ID" value="ABX06306"/>
        <property type="gene ID" value="Haur_3670"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3670"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_0"/>
    <dbReference type="OMA" id="SWNNNHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3709-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="53"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="440" mass="48525" checksum="3600BFF8E644A9AC" modified="2008-01-15" version="1">MTLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVGDFAPSQFPIPEALRDAAIESYSAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQIISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGSKAIEVPTRPEDGFLPTAELLAPFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWELQLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVGAWAPHPEQEATAHILNSIDVLDDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQGAIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVPFQAFGLRQETGWMRLSVGAVSIADVEQCIPRMRAILERVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D7</accession>
    <name>A9B6D7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0188"/>
    <dbReference type="EnsemblBacteria" id="ABX02840">
        <property type="protein sequence ID" value="ABX02840"/>
        <property type="gene ID" value="Haur_0188"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0188"/>
    <dbReference type="eggNOG" id="ENOG502ZASA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1052504_0_0_0"/>
    <dbReference type="OMA" id="PMEASIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-191-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="27915" checksum="7754677EAD7BD38A" modified="2008-01-15" version="1">MSPFEILVVSLILTLAIALPFVYARLVTGGRKINRRPLPPIDLINSALARSAETGQPIHVSPGSGSLDGSTINPETLAGLVLAQRITDIAARRGAGIAASSGDPIAHLALRGTIRRAYRDAGYSEDYRPELIQLLAANDPIAFSAGLSNRITSEPMEASITVGSFEQGYLLFAEPGRAHNILQIAGTTDQQALTAALLTANGTLLGEEIYAAEAYITPTPLGFARILTHDVLRSVIIGVIILGIILVSLGQLAILPQDFPLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L6</accession>
    <name>A9B6L6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1682"/>
    <dbReference type="EnsemblBacteria" id="ABX04325">
        <property type="protein sequence ID" value="ABX04325"/>
        <property type="gene ID" value="Haur_1682"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1682"/>
    <dbReference type="eggNOG" id="COG5267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026001_0_1_0"/>
    <dbReference type="OMA" id="MANQHAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1706-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734591" evidence="1">
        <location>
            <begin position="31"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="525" mass="58415" checksum="327ACB3E4D14F0BE" modified="2008-01-15" version="1">MLNRRNFLKISGLAAAYSVLPLWLSACDRAAPSAIAQPTWELEAPTNGDHRSRVAIRHLLNRLSYGPLPGQIEQVQALGWDAYLEQQLNPSQLDDSALEQQLAQFTTLKLSSAHLIEHYPKGANGPRLIMRELQAASLLRAASSQRQLFELMVDFWSNHFNIYIGKNQVKWLKTADDREVIRQHALGKFRDLLLASAKSPAMLVYLDNAENVRPGVKVGKKMLGLNENYARELLELHTVGADAGYSQADVQAVARVLTGWTITRANSEQPGLFQFLPKFHDVMAKRIDFLQLDLAADGEIEEGELLLKLLAEHPKTAQRLAYKLCLRFVSDDPPADLVERVAQAYLQHDTDIRAMLNMLVNSAEFLAAAQQKIKQPMHLLISAIRATNSSITKQAFKGKNNLLDQLETLGQMFFNWPPPDGYPQISSAWINTGAMLSRWNLAFALAEGRIDGLKTDVPKFAKQPSQASELVDTLADYLNLSLAAESRASLIDYLNDSQSPNPTVDQTKIAGLLGLLLTSPEFQLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Y5</accession>
    <name>A9B6Y5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit I</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoI</name>
        <name evidence="7" type="ordered locus">Haur_3216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="316274.Haur_3216"/>
    <dbReference type="EnsemblBacteria" id="ABX05853">
        <property type="protein sequence ID" value="ABX05853"/>
        <property type="gene ID" value="Haur_3216"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3216"/>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067218_4_3_0"/>
    <dbReference type="OMA" id="PVVDWVM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="18839" checksum="B440EE203976941C" modified="2008-01-15" version="1">MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSLCAAACPADAIYVVPGQNDPANPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQYELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQLNPPAQIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B702</accession>
    <name>A9B702_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3233"/>
    <dbReference type="EnsemblBacteria" id="ABX05870">
        <property type="protein sequence ID" value="ABX05870"/>
        <property type="gene ID" value="Haur_3233"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3233"/>
    <dbReference type="HOGENOM" id="CLU_2788198_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3268-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="68" mass="7397" checksum="D60B8AE3C6CC2BAF" modified="2008-01-15" version="1">MSEPLFKDADEFERTYVGEQASDATVVPPVAANPAFEHGTMPTPPLYVDRDGLHAAPVTLDEPAKRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B758</accession>
    <name>A9B758_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3705"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06341">
        <property type="protein sequence ID" value="ABX06341"/>
        <property type="gene ID" value="Haur_3705"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3705"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_6_4_0"/>
    <dbReference type="OMA" id="YDRFFHL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3747-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02857">
        <property type="entry name" value="E_set_CDase_PDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004185">
        <property type="entry name" value="Glyco_hydro_13_lg-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017069">
        <property type="entry name" value="MalZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036918">
        <property type="entry name" value="Maltodextrin_glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="134"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR036918-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR036918-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="617" mass="69108" checksum="117293AE92688994" modified="2008-01-15" version="1">MHYPTWTSAVHHDGSALYLQPSQPYHLGQQVTVRLRTPLAAPITQAFIRICPDGEQTFVAMQPAERTETIQWWQGQITLSMPRTGYRFWLMTEQGGWWLSAAGMQRSTPTDATDFKLLADYHAPTWVHSAVFYQIFPDRFCDGEPSNNVVDGEYTVYGKPTIARQWGEAPQKATGGIEFFGGDLQGISQKLDYLAQLGINALYLTPIFTAPSNHKYDTADYLQIDQHFGGEAALAELRQATQRYQMKLMLDIVLNHCGYTHHWFTAAQADTNAPTADYFSWKQHPNEYESWLGHRSLPKLNYTSHGLRQAIYGSEQAIVRHWLRQPYAIDGWRIDVANMLARQGSSQLGHKIGRALRRAVKAESPEAYLLGEHFYDGTNHLQGDELDASMNYRGFTFPTLQWLVGFDMASVWNLVWEDRALLPTEALGEQWLAFLAVIPWQVALQQFNLLDSHDTPRLLTIVGGDLSLHHVAVTLQMTFPGVPCIYYGDEVGMQGGGDPECRGCMPWDAQVWDHDLLAFYRSLIGLRRSSSALSVGGFQLLLAEGDTVAFMRRSADECLLIVAQRAATSIPPIPMFATGLTDGTSFIKVAGTTKITIQAGVLVLPQTGISASIWQMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C9</accession>
    <name>A9B7C9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3776"/>
    <dbReference type="EnsemblBacteria" id="ABX06412">
        <property type="protein sequence ID" value="ABX06412"/>
        <property type="gene ID" value="Haur_3776"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3776"/>
    <dbReference type="eggNOG" id="COG3217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028286_0_1_0"/>
    <dbReference type="OMA" id="GYPFLLI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3818-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOSC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="130"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="275" mass="30939" checksum="B40053391791C3E1" modified="2008-01-15" version="1">MAQVVDLTIYPIKSTAGIPLDQAWLELRGFANDRRWAIVASENRRILTAREYGTMLAIQSQVGPDGLLVHLPNRAEPIALPYLLQPIERVNLWAEEQHPAMVYNQAINQAFSEYLGIDCLVVYMGEGCERPLPTDMPSGYTGRITDRVSYADDYPILLASQASLADLNQRLEQPAEMRQFRPNIVIDGERAYQEDQWQWLQIGECLFEVAQACPRCVLITADPTTGQKHAQQEPLRTLARYRKTAGGVPFGIQLVPRKLGTIRQGDQVVVLKQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F6</accession>
    <name>A9B7F6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0277"/>
    <dbReference type="EnsemblBacteria" id="ABX02929">
        <property type="protein sequence ID" value="ABX02929"/>
        <property type="gene ID" value="Haur_0277"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0277"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2093460_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-280-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="14701" checksum="C7C0866BDA53A5A1" modified="2008-01-15" version="1">MVPQTIAVVNNDLALLDLLQELLLEAGYATTTYLTTDLTYQQLRDSQPSLIILDVGLQASAPGWPLLKLLHFDPNTVQIPVLVTTVDHAFIQGKQAFLQAAGCDVLELPASFTDLVAKVATLIGAPLARIIPTSDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J8</accession>
    <name>A9B7J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0319"/>
    <dbReference type="EnsemblBacteria" id="ABX02971">
        <property type="protein sequence ID" value="ABX02971"/>
        <property type="gene ID" value="Haur_0319"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0319"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1308717_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-322-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="23"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="45"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23528" checksum="A3BBBECCD1DA0F42" modified="2008-01-15" version="1">MDTTSFPEFWHSIPRDIAALMPNSPELPYDAHLILNSIARHSHELYQHSLRVGHMAWHMSHSLGVPTYERQQIWLAALLHDCGKTRMPRSLLFCPPPGSPHWEVALYQQHVNESLDVLHAYPTLHLLIPLVAEHHERIDGTGFPRGSKYPARSAQIVALANALDHLRAQPSSLSPNLQGLIDQAIDHHWDSAVAATALSAWQQTKLAEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M5</accession>
    <name>A9B7M5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-alkenal reductase</fullName>
            <ecNumber evidence="3">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0347"/>
    <dbReference type="EnsemblBacteria" id="ABX02998">
        <property type="protein sequence ID" value="ABX02998"/>
        <property type="gene ID" value="Haur_0347"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0347"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_0_0_0"/>
    <dbReference type="OMA" id="THGWVLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-350-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="279"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="37925" checksum="15D22B520D7A3B6D" modified="2008-01-15" version="1">MSNPKRTVGIGGLIIAALALSGVGGGLVGGVAGYRLAQVDQTATAVAVTPTSATQQTTDNLTAQPVVASTNDAVVQTVAKASPAVVKIISTVVGGQASGSGAIINEDGYIITNNHVVEGQSRLQVIYSDGTSHNAELIGTDAFSDIAVIRVLDAVPATISLGDSDSLQPGETVVAIGSPLGKFQNSVTVGVVSALDRTIDSMEGLIQTDAAINHGNSGGPLINLKGEIVGINTLVVRGDIGSIDEAQGLGFAVPSNIVREVSDALIANGQVIRPYIGIRYELLSPETAELGIANDKGAFVTNVDEGTPARRAGISRGDIILAVNGEEITQRHSLQRLLLQYKPGDTVTVTIERNDQQQEVQITLAERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P9</accession>
    <name>A9B7P9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate_J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1784"/>
    <dbReference type="EnsemblBacteria" id="ABX04427">
        <property type="protein sequence ID" value="ABX04427"/>
        <property type="gene ID" value="Haur_1784"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1784"/>
    <dbReference type="eggNOG" id="COG3299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_339138_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1812-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="67"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="689" mass="76852" checksum="A2DE29C9F626D6A2" modified="2008-01-15" version="1">MTIHKKQFNDIYASMVADSRQRLPRLSDFEEGSVVRSLFESFAYELAVLYEQMDLVYQAGFIDTAEGAQLDRVVAILGIKRNEPDFATGSVTFQRDSTSEETLIPIGTLITTKEDPKQTPSKKAYITTEEGRIAPGTATVEVHVRAEERGKHMTTAEQTVIVMPRPLPGIKSVTNPKAIGFRGRERETDQELRERAKQTLLASGRASSLSIENALLSLPEVREVRIHEDFHNNPEGRPGSIEVFVDGMNEHNERQLRQRLDEVRAAGIYVVLKPAAPINVDAVIHIAANEQIANAEKGLLETQVREAVEAYFGRLGMGQPLLFSQITSEILQVKGVNDLINLELQLYREAESKAQGLVQLTRSTNLSQTLLIELPCELRTLDNQRFLATNPASFAPNQAMIELQVQAMLAGRSGELATSAALWEELVINQTKLTISNPQPILLQRTKHTPQDKRLESAISELFNAASIRVAAEPKDLPILIFIKLVEPGLERDEKRRKIEGAIQEYIAGLTLGSAIQASEIEKKIRLYHRKDFSLRMLAKPFQSNERPEDSAIQVSIIERPVLANLLIYSERVELTGKLELTVAPTTSDSQRRQICYEVRRAIMAYLDDLAPEQDLELAQIEALAKAQLQVLQVAFNPKHCQLYNVSTNPVGVLAERNNGKVVKIASFEKVFLASDSASDPALRFVIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7W7</accession>
    <name>A9B7W7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1852"/>
    <dbReference type="EnsemblBacteria" id="ABX04495">
        <property type="protein sequence ID" value="ABX04495"/>
        <property type="gene ID" value="Haur_1852"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1852"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_559937_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1881-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731991" evidence="1">
        <location>
            <begin position="29"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="85"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="487" mass="53444" checksum="0843496D0F1D4B83" modified="2008-01-15" version="1">MNTKRIIACWLVAIIVSIGFGSPQSSQAQNAQAQPAQITIDGLAVKLPFQPGAEWRVTAGWEAANHQQAWNYYAVDVVPVNQACLGRPILAMAHGFIESNNGHELQIDHRVNNYRSLYSHLDTVSPGLAVGTEVFQGQQIGTCGGYPNFAPHLHFQIFQGARMASSGVIPIPIDGITDANRLRSGQRGLYSTNQSQPQLPTANYRPLRLFWHGERGDNFTTASTQAEISAAANAYTSIRTEGFVFSHAGSGRVPLQQYWHSGRGDNILVATNAGINDARNAGYSFVRTEGYIYATQQQHTVPLKLFWSDTRQDNFTTSTAEGEQSALAAGYSFVRIEGYVFVARPLQLYWHSDRGDNFPTATSEGIASAHISAYGFIRTEGYVFADHLPDTVPLKLFWSDARQDNYITATAEGEQSALMAGYGFVRIEGYVLPTNGADLRPLELFYHDGRGDNFTTGTVAGATDAINHNYQLIRHEGYIYGTLPAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X0</accession>
    <name>A9B7X0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1855"/>
    <dbReference type="EnsemblBacteria" id="ABX04498">
        <property type="protein sequence ID" value="ABX04498"/>
        <property type="gene ID" value="Haur_1855"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1855"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1884-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="831" mass="94975" checksum="5B5153FA8AAA88A5" modified="2008-01-15" version="1">MKQRQAFAAWLRHVRHELQYSQDQFAEQLNYATVTYRKVERGLAPSAAFLERLAMVLELPASDMRILHDFANSDTALQALSLPDHLEHLQPQVAQAKPAIAATPHTLPMLPYPLIGREREVETLTKLLQHPQHRLITVIGPPGVGKTRVAQAVGWASLGHFCDGIWYVEGIQCTTIADFWVDIANMLGRSANSSMTLIEQISALIGQKNSLLILDNCEHLSEINLGLAQLLAQCSGLKILVTSRTSLKLRIEHLFWLHPFPTPDPQSSNLSAIWQNPAVQLFCQRAQASNHEWQINDSQAATIAQICQHLDGLPLVIELAAVRTQFVTPTTLLARLSNRLGILTNTMRDAPAHQSTLRRTLEWSYQLLDSNEQQIFARLSVFATDSDFEAIVAVCADLAPSNDDIFDCMASLVAKSLVIHRPDPQGNSRFGMLATIREFAASLLAEQQQTHHYTQRYINYYIELAEKIDRELRGKEQIQLLEQLESEFHHWQAVLRLCLNQQQYHGFLRLFAALSQFWYGHGHFMEAWQWLSAVDQALNHVDSPIIQARAALGAGIVTNIHHCLDLPLGYLERALDLCQQLNDQQGIATCYLLLGLIMMRKHQYVQATRWLNQSLNYFESSVEYWLLSINHLLLAQLNIYLNDLDQASRYLDLVGHSPQLRLDPFRSSWYQSLQGHVAFYKRCYTEALTWHQQSLVERQQLGIKGDIAVSWLRIAQTERALGHYQPTRNALEQSLKLWQMHDNQENVLHCLEEFAALLAYDQQHQTATYLLSYAWFQREQRQLPHPPIDQARSQQFGMWLQNQQPSNVWREAWSYGQTLKLDQVIGFVLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B842</accession>
    <name>A9B842_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3339"/>
    <dbReference type="EnsemblBacteria" id="ABX05975">
        <property type="protein sequence ID" value="ABX05975"/>
        <property type="gene ID" value="Haur_3339"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3339"/>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432068_0_0_0"/>
    <dbReference type="OMA" id="FAHEWQH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3376-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008757">
        <property type="entry name" value="Peptidase_M6-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05547">
        <property type="entry name" value="Peptidase_M6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735362" description="Peptidase_M6 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M6" evidence="2">
        <location>
            <begin position="416"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="620" mass="67929" checksum="535EA81219621CF2" modified="2008-01-15" version="1">MRRWRICLLLWMLVGCSATAPTTSTQIPIQPSLPTPAQTLSPTQALATSIPIIADEAAVERASQQGLERDLAQLAVDWRLISEKPQPLRLEMPPPYERRSFWVTDLTSNQQRNISATLQLSTTHLLIYVADDLPVEQQALINAAQQFEQVGWPLLAKWYPQQAWPQVPVTVLNAAVNGAGGYYASDNELPQAINPYSNEREMLVINAAAMPPSDFGYVATLIHEMQHLLHRNVLSHPATWLNEGASMLSEDRSGYSNDSLALDFLASPDTQLNAWASSPGTALKHYGAAQLFLSYLDQQLDGLPMGTLAAADAGDNLTSITSLMTTRYPDLTSFDQLFAAWAVANWVNDPTVADGRYGYDLPRAVLPEQAQSSEQNLSIRQFGSDYLAFENASSERTLEWQGNNTVPIFAADVTSSATWWSGRGDARVSTLTTAIQVPSAGGSLIYRRWFDLEQDYDYAYLSLSQDNGQTWQAIATQASTGANPVGLNIGAGWTGQQTTWQAESVDLTPWAGQQIQLRFWVINDEAYNAAGLALSDLTIDGVTAEWVGTGFVPVRNQLAQRWVLTAVLYDQAGVAEVVSIPTDNGQARWLIPANRRAVLVVNATTQGTTEAANYSYNVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ2</accession>
    <name>A9AUJ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD/TfdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1876"/>
    <dbReference type="EnsemblBacteria" id="ABX04519">
        <property type="protein sequence ID" value="ABX04519"/>
        <property type="gene ID" value="Haur_1876"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1876"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044153_0_0_0"/>
    <dbReference type="OMA" id="HNEQAYT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1905-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="48"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="39790" checksum="7E057A64E45B3F35" modified="2008-01-15" version="1">MTTSDDKKPSLKGQLGAGRRSVSVSQESLIKSQPLLSDSALPLLVTPAVEGLNLITWANSHRPFIETNLAQHGGILFRNFNIKTLEEFQRFVSEMSNELLEYTYRSTPRSKVSGNIYTSTEYPADQSIPLHNEMSYTTSWPMKIWFCCLIAPQQQGETPIADSRRIYQRLDPAIRDRFAEKKVMYVRNYGEGIDLSWENVFQTDNKADVEEFCRLNQIDFEWKSGNRLRTRQVCQAVAKHPKTNEMVWFNQAHLFHVTSLPAAVRDMLLAEFNDEDLPRNTYYGDGSPIEPEVLAEIRHVLDQETVMFPWQEGDVLMLDNMLVAHARSPFVGPRKIVVGMAESVDAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUT9</accession>
    <name>A9AUT9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3893"/>
    <dbReference type="EnsemblBacteria" id="ABX06527">
        <property type="protein sequence ID" value="ABX06527"/>
        <property type="gene ID" value="Haur_3893"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3893"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_787028_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3935-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="352" mass="37582" checksum="0578DEF454E8588C" modified="2008-01-15" version="1">MATRFRASLLGILLLVGIGLQGWVRPQAPNAPTVLNENFDSFNDVLADGWVIVNGSEPRNDDTSDHNRWKQGRSNGNDMDSHSGANNSYAGSSWEASTFGSNSIVSNWLLTPPLLLENGKTVSFWTRSLGCSGGPDRLDIRYSTAGTSTNVASGSNTGDFSNQLGRINPDQEFGHDADGSDGYPCSDWAQFSYTLSGINQPTIGRIGFRHYIVNTANRGLYIGIDDFSYSGDLGGGTPTPITHTPTVTATNTATATNTPTSTPTSTSTRTPTNTVTNTPTNTPTNTRTPTNTPTGTPPTPTFTHTPTRTPTNTPTNTPTRTPTNTPTRTPTATSVPQIPVYKVFMCLIQNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW0</accession>
    <name>A9AUW0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3914"/>
    <dbReference type="EnsemblBacteria" id="ABX06548">
        <property type="protein sequence ID" value="ABX06548"/>
        <property type="gene ID" value="Haur_3914"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3914"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_723143_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3956-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="382" mass="42025" checksum="C2A88014DF9E12F4" modified="2008-01-15" version="1">MSVPIVQIQYQQLEQLAQRFAKQQTQVQAILQSLRQTIQALEHGGWMGDAATACFKEFHAEIVPAYCKLQHVFSESQTSLNQIAQLFHEAEAEAAGLFRGEMAQAVGNASPWQILNHLETNLSEQLSRFQPETLEHMLGAIDPQSFDITTVLALIENASLVERQAILQNPEVLNLIRASAGDQAYIVMAVLSIGSFRWLASQQGADGCIAIFLTDPLTHEPRTNNFAQWICTVPNSNEPSSQISPPNPLTGSMNCWEFVLFSAFLGGNITYDELDAVYSEVGTPITLEEHKQAIYTALGGEHSTEWNPCNDIPAGSIIFFDDGSNPIAHVAIATGREINGSPELISLWDRPNTIDSVQFTTIEALNGSDYTINVAPNPWLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUX3</accession>
    <name>A9AUX3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3927"/>
    <dbReference type="EnsemblBacteria" id="ABX06561">
        <property type="protein sequence ID" value="ABX06561"/>
        <property type="gene ID" value="Haur_3927"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3927"/>
    <dbReference type="eggNOG" id="COG4097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083317_0_0_0"/>
    <dbReference type="OMA" id="WRVLHRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3969-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="34459" checksum="69BC9F0E1032CF13" modified="2008-01-15" version="1">MSASETDKAARLAAIRAKNAAQKAQAIEPTEPVVQDKAARLAAIRAQNAAQKNESVVTSQVVATLPLGTTQPSTAPTPIAKATPNAPTPSAEEMLEDVSANLMSLMIALIIGIVAAVLVMPRWIPGLSSSLIGDQPKAFWYLSRSSGLVAYSLVWLSMLFGLSLTGKVARLWNGGPTMLDLHQHASILGIGFGLFHTVILLGDGYSNYTLKQLLVPFASSQYKPLWIGLGQLGLYGLALVTVSFWLKRWIGRGAWRAIHYASFGLFLMVLAHGIFSGTDTSTPLVSLWYWATGASVVFMTIYRILITRRNKPLPSVPVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUZ3</accession>
    <name>A9AUZ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3947"/>
    <dbReference type="EnsemblBacteria" id="ABX06581">
        <property type="protein sequence ID" value="ABX06581"/>
        <property type="gene ID" value="Haur_3947"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3947"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464432_0_0_0"/>
    <dbReference type="OMA" id="MANEPAH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3989-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="602" mass="64053" checksum="9F2CA2BCC8F6E65E" modified="2008-01-15" version="1">MTVLQPGVVLNQQYEIIKKVGGGGGGNVYEALDLNLGRSVAIKHLILPSDDAVKHFKKEARLLARLEHQCLPRVYNQFDEGPSQFLVMEYIDGTDLAEYLNQQAGPLALQQVLPWADQLLKLLEYLHTAHELPIIHRDIKPANIKLSASGQLKLIDFGLAKSALSTQINNVYQSVRGYTSTYAPLEQLVPNDNEHTDERSDIFAFGVTLYHLLTGKVPVNAQQKPIDATNRHAMVIQAKPDPIVRPKLLNPTIPDYVDAAIMKAMAINKLDRFGSAAEFRQALNPSVAVKLSSGISSLLGSQRRPTQPVGGLSSQPAPAKISQPLRSIPSTSIADQAQSTLPTPLVQNPNAQAKPLKRVAPWLMLILVGLIGGGWWWVKANPTGASANGATQTQAANLVVNQVPALPSTTPTDTGSTVGQPTITLGLATATLVEPSATATVEPATAVVVQPTARPATARPVVQPTARPALQPTNPPVVQPTNPPPPPSDRDGDGFIDDVDACPDVAGPNNGCPVVEPTAPPAVADTDGDTIPDDRDACPREPGDPSRNGCPKPVEQATNTPRPTETPNLSTDRATPRPTNTPTPNINPNNPPSPPTSPPMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV90</accession>
    <name>A9AV90_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03168">
        <property type="protein sequence ID" value="ABX03168"/>
        <property type="gene ID" value="Haur_0519"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0519"/>
    <dbReference type="HOGENOM" id="CLU_1064653_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-527-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28947" checksum="9A67FC6A733EBB9F" modified="2008-01-15" version="1">MSELRGFSLSQEELFVCLIVADLPLPLGFDDLANQVFGDLPEQYQQYLLGAAERSLIAHGLLELTDDQPVLEPMVAEWLSIISQPSQTWVILHQPAGQKQQANYIHHAKQQYLFHRGQGGIHQLIALPHTREIVQAALDIIEPAEVEVAETLTGSLSEAVFRSIASMRTIKREQVVEQLQAGGLTANVAEAFGQSFEQLRSISALALLQNKPESSVQQAFTLVCGEQQQWLLVPEAEGSLYVRNLDLNALVQVLHNFAHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA2</accession>
    <name>A9AVA2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03180">
        <property type="protein sequence ID" value="ABX03180"/>
        <property type="gene ID" value="Haur_0532"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0532"/>
    <dbReference type="HOGENOM" id="CLU_1852447_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-541-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15387" checksum="8690A5989AB0B7C8" modified="2008-01-15" version="1">MLIPIDNIPIFKSIIKIALIEDMEPAMIESLIPMLGIVASAIAIALLTKHPKQQLISSASAVVFWFAVWCVLVGPEYLLFVAYLVWLVVLAVVIVMAINMARALLRTFQKEAHKRPEPTTHYPPITQGDIDQGINQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVG6</accession>
    <name>A9AVG6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PrcB_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04657">
        <property type="protein sequence ID" value="ABX04657"/>
        <property type="gene ID" value="Haur_2014"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2014"/>
    <dbReference type="HOGENOM" id="CLU_2012099_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2043-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025748">
        <property type="entry name" value="PrcB_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14343">
        <property type="entry name" value="PrcB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PrcB_C" evidence="1">
        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="13449" checksum="1308F8D5E8159DB1" modified="2008-01-15" version="1">MCLLELSEQRDNHLTAMVNPTVRNHIQQSQQPQTVMIACFLGLRQAGGASLSIQSITISEAMIHIYATVSLPQPHEFAESGTHSPVSVVRIDQGAIPRNIPLTLRLINATTTQELANNSVIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL8</accession>
    <name>A9AVL8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3986"/>
    <dbReference type="EnsemblBacteria" id="ABX06618">
        <property type="protein sequence ID" value="ABX06618"/>
        <property type="gene ID" value="Haur_3986"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3986"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623706_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4028-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="48231" checksum="EF8348B2594993B2" modified="2008-01-15" version="1">MTSYSITGRVVRTIDLAPLANISVRFISQAGYLSNVANRSLLPAGQVDWTRSLTGFSGTRWECWEQQINSKVAIAWGDFRDGALIYNPHLSDDGRVFHSDKTYLMPEVSPAQEVSWTRQITGFAGSRWDCWVQYIDKRVPISWESFRDNALIHNPQLAADGRLFQTAKTYLIPDVAPVARAACEVKTDAQGNYRFDNIGAGAVGLLEVNVAGYTPVRVPVIVNNTINQPINVRGGGSGVRSAHPSYNALHPKVRAIIDQALFMLGDEKTVYDALPTNLQQMCYGAQFASNPNHQYYKDIVCADLVSICLAAAGFNVNWNSGANPHMAQHYAPGPATLQEITDANDWQPGDVLVFGNNGAARAGHVTLYVGPFQGTDRSGTNYSLSANFDVVEASMNFDLANGQRWGLGNIATTRQQCLQGKRGYQWVKRVRLKEVAALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW37</accession>
    <name>A9AW37_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0627"/>
    <dbReference type="EnsemblBacteria" id="ABX03275">
        <property type="protein sequence ID" value="ABX03275"/>
        <property type="gene ID" value="Haur_0627"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0627"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_1_0_0"/>
    <dbReference type="OMA" id="NRIQGFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-636-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="40"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="305" mass="33859" checksum="F131704640DB6544" modified="2008-01-15" version="1">MAGTMRVTFWGVRGSYPVPGSDTVGFGGNTPCVEVEANGHTIILDAGTGIVRLGNDLLRRAKERGGPVRATLLFSHMHHDHTQGFPFFTPAYVGSSILNIFGPRVFERDLEETLAHSMLPPSFPVSLGEMNSLKFMRNMTETDVLLFDANQDTVTVKNFYHDQITDDPDVVQIRAMRSYAHPEGVFIYRVQWQGKSVVYATDTEGYVNTDQRLAAFANQTDLLIHDAQYSEAHYLGHAGYNATQGWGHSTPQMACAVAMAAQAKRLVLFHHEPRYNDAMIRELEQASQAIFANTTAAYEGLTIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC8</accession>
    <name>A9AWC8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2138"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH74">
        <property type="family name" value="Glycoside Hydrolase Family 74"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04778">
        <property type="protein sequence ID" value="ABX04778"/>
        <property type="gene ID" value="Haur_2138"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2138"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004180_1_0_0"/>
    <dbReference type="OMA" id="YSSWWPD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2166-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734377" evidence="2">
        <location>
            <begin position="23"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="831"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="942" mass="99325" checksum="6DF745AC032C738F" modified="2008-01-15" version="1">MRMLKMAAAVVVLFAGVIQAMVAVPQSRAASTQPYNWSNVEIVGGGFVPGIIYNPTERDLVYARTDIGGAYRWNPTTKRWIPLTDWIGATDWNWTGIDSLATDPVDPNRLYLAAGTYTNDWTSANGAILRSTNKGNSWARTDLPFKLGGNMPGRSMGERLAIDPNKNSVLYLGTRGQGLWRSTDYGATWAQVTSFPAIGNYTDPYFNDRIGVVWVTFDPRTGTSGSASQTIYVGVADTTTSIYRSTDGGATWAALPGQPTAGYLPHHATLASNGMLYITYSDTPGPYDGGKGDVWKYNTATQAWTNISPIPSSSADDYFGYGGLAVDAQNPNTLLVTSLNSWWPDALIYRSTDGGATWSGIWEWANYPERTFRYTQDISTSPWLDFGGNATAPEVAPKLGWMIGDIEIDPFNSDRMLYGTGATIYGTDNLTAWDTGGKVALDVRAHGLEETAVLELVSPPEGVHLVSALGDIAGFYHTDLTKAPPWSASLKFGSSTSIDFAGTRPNVMARTGYVGEGSTVKRVACSWDGGQNWSHASSEPTGSVGGGKIAMASDASMIVWSGTTAPVSYSMGCGNSWSASAGIPAGAVVIADRVKSTTFYGIANGTLYRSTDAARNFTAVATGLPTKSAKIEAVLGIEGDLWLAGGQDGLFHSTDGGTTFSKIAGVQVANVVGFGKAAPSQSYQAIYITGAIDGVEGFFRSDDGGTTWVRINDDQHQYGSTNETITGDPRIYGRVYIGTNGRGIIYGDIAGSTPTNTPAPATATATRIPTATSTSVPPTATSVPPTATSTRVPTATPLTSTAIPYTPTPTSTRVPTATPITPTSLPYTPTSTPAPGGCRINYVVNQWNTAFTGGVTITNLGAPISGGWTLTWNFANGQTVTSSWNTVLTQTGSAVTAKHSADWNANIPTNGTQSFGFIASHNGTNAVPTNFVLNGVACSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF5</accession>
    <name>A9AWF5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4082"/>
    <dbReference type="EnsemblBacteria" id="ABX06714">
        <property type="protein sequence ID" value="ABX06714"/>
        <property type="gene ID" value="Haur_4082"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4082"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589090_0_0_0"/>
    <dbReference type="OMA" id="RRFSWFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4126-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="409"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="55111" checksum="21CB59CE2EE2625A" modified="2008-01-15" version="1">MSTEAFQAGVAALKSGNKALAREHLMKVVEQDETNEQAWLYLAGALEDPAEMRISLENALHINPQSKRAQQGLEWLRKQHPAIFVEPTPALPAATAPAYTGATVALADLPLADNPLPDQPITPTPFPATQPLGQASLPATQPLGNGPLPATQPLAPPAVGEVPDVLPCPRCGAPTRYVEQRCRKCGMNLTIKTERQTQSKIPILIPGLLSLLPALLWIFLAGNIFVRAFEEYSDFQAQVRVIAPMNKIVSEEEKKIQDEKIAELEEVLFDFITPPLNIAVSLLLIGIFGIIMAIALMRRKKYGFWGTLIYNGIFLFIFIALIVTLKRLELLDEESSQQTLLDILPWAMENPILATYLIFLLAWAYININLLFIAVGLYTLIVLMLGFAWRTISQKAVRFVPQFEELAEADGHFNRGVVYQKRGMWYLSMLEWERAVKLNPRDSTYRHALGLIYEQLKRPADALQQFEQALTEDPNNLRISQDRDRLVQTLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWM6</accession>
    <name>A9AWM6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4153"/>
    <dbReference type="EnsemblBacteria" id="ABX06785">
        <property type="protein sequence ID" value="ABX06785"/>
        <property type="gene ID" value="Haur_4153"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4153"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645247_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4199-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="311"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="425" mass="46876" checksum="6D916EB77FFA3383" modified="2008-01-15" version="1">MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASEISIHALQCRRYEKDFLLNAGNIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQAWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQNNIQILTDQSYDLAEVKNHASQASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLSARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMIQQQAQVIAEMSTPILPLTSHALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITAVPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIVGLGIDLGDIATCSSLQSGIDRVLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWX9</accession>
    <name>A9AWX9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0732"/>
    <dbReference type="EnsemblBacteria" id="ABX03380">
        <property type="protein sequence ID" value="ABX03380"/>
        <property type="gene ID" value="Haur_0732"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0732"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2194300_0_0_0"/>
    <dbReference type="OMA" id="LYAMNVT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-744-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="46"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13493" checksum="BF2BA6380DF0EA98" modified="2008-01-15" version="1">MSDVQAVIRREEWDDVVLLHILTNSVDAVSAATIEHACTQMKPITVLDFADVAFINSAGISVLLKFVVAARKNGYKVFCLHVSPHHQKIFKMVEMTRFMPVIEEQDLAAYTNAQQSSISNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX08</accession>
    <name>A9AX08_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04816">
        <property type="protein sequence ID" value="ABX04816"/>
        <property type="gene ID" value="Haur_2176"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2176"/>
    <dbReference type="HOGENOM" id="CLU_1568607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2204-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735289" evidence="1">
        <location>
            <begin position="21"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="19231" checksum="3D54D4B8BBA24369" modified="2008-01-15" version="1">MRRFGWMLLLILTVGCSVNSKNSQPQPIITETGEHVTVFPNYIAIVVPGYELTCLTDPVLSIQTADGWLPLEDFIMQPHYLDDKFNFVAGMCDEVGCNKINHEHPLAIGLPLYQHIGERKHLLDRTGEIKMLPAYRMVSPTQTVKLDITYFLDDACSKQQTYSTTIDLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX28</accession>
    <name>A9AX28_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04836">
        <property type="protein sequence ID" value="ABX04836"/>
        <property type="gene ID" value="Haur_2196"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2196"/>
    <dbReference type="HOGENOM" id="CLU_1494292_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2224-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20116" checksum="7FD2EABB64665B3D" modified="2008-01-15" version="1">MDVLYQSLTPVIWDIPLSLDLLLLVEAPKPMTTPITCWWVANQLLALSANIVWEVADFSWFFALTDILVDSHMLSQAETMTQDSRIAIYLDPGLRTITLVSPPDYHPERTTIDRAAVITLGTMLTTTDLDQTIQGLKHAIETPDCAITNDFIAQEADNPPVADGLLEWCQAWFQAQSQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX52</accession>
    <name>A9AX52_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2220"/>
    <dbReference type="EnsemblBacteria" id="ABX04860">
        <property type="protein sequence ID" value="ABX04860"/>
        <property type="gene ID" value="Haur_2220"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2220"/>
    <dbReference type="eggNOG" id="ENOG5030T8S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841557_0_0_0"/>
    <dbReference type="OMA" id="WENHAIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2248-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="36331" checksum="FCFB40C17F4D6CE8" modified="2008-01-15" version="1">MNLTEPFDDQAQYQAVCRLIEVDLAALPEALAQALQAAFAEFKQGKFSQIAALLPAWLGQQFPVATPVYAQLGAAQLYGWWYYWAQDQLLDGDGAADLLLGAHLALLRQIELYTELGVTQSPIWPLFRQLTVQSALGHQQELRYRLSELSVLGFEQLATFDQTVLLARAQPFFFCSRAQAWLAGADPFGAAANLVIEALEILTLARQLSDDASDWIDELKQDKLNSVACRFLGYLQQQAVFTDFSQLTAAQVAGQQILHEAFWPALEQQNQRLIEQTLQKLDAANQQQLAGLLRHQAKLNHDLWENHAIYRQQLRGFFGLAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX86</accession>
    <name>A9AX86_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4174"/>
    <dbReference type="EnsemblBacteria" id="ABX06806">
        <property type="protein sequence ID" value="ABX06806"/>
        <property type="gene ID" value="Haur_4174"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4174"/>
    <dbReference type="eggNOG" id="COG2718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049702_2_0_0"/>
    <dbReference type="OMA" id="QYFAYIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4220-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006698">
        <property type="entry name" value="UPF0229"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30510">
        <property type="entry name" value="PTHR30510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04285">
        <property type="entry name" value="DUF444"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="41702" checksum="3083012F6AE36533" modified="2008-01-15" version="1">MQRVERDLNRFRQIVRGKIKKDLRKYISHGEMIGRQGKRLVSIPVPSIDLPRFRFGKNQGGVGQGEGDNGDPIGRGDGSQPGAGEAGEDSGQHSLDVEMTIEELAQLLGEELQLPNIQPKGSKNIISQKDKYSGITKVGPNSLRHFKRSFREALKRQVASGQYDPDDPVVVPIRDDMRFRTWKTTEMPESNAVIIYSMDVSGSMGQEQKELVRVTAFWIETWLRSQYKHLEMRYIVHDAAAKEVTQDVFYRIREGGGTKISSAYRLVLKLIEEHYSPDEWNIYPFHFSDGDNWGGGDTRECVELLRNQILPKVNLFCYGQVRSLYGSGRFAHDLNENFRANETMVVSEIADRDDIYNAIKAFLGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH9</accession>
    <name>A9AXH9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fabD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0745"/>
    <dbReference type="EnsemblBacteria" id="ABX03393">
        <property type="protein sequence ID" value="ABX03393"/>
        <property type="gene ID" value="Haur_0745"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0745"/>
    <dbReference type="eggNOG" id="COG0331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030558_1_1_0"/>
    <dbReference type="OMA" id="AANYNCP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-757-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="6"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="31467" checksum="B80902315BA66D25" modified="2008-01-15" version="1">MTIGLLFPGQGSQKVGMGREVYEQSPAARAIFAEANAVLGFDLAGLCFDGPEADLTATENTQPALLTVSVALLAAIAEAGVDLHPSIVAGHSLGEYSALVAAKALDFATALRLVRQRGELMAQASEGAMAAVIGLDLGPLEAICANVSKLGACVVANQNAHGQLVISGASAAVAAASEQAKAAGAKKIMPLNVSAAFHSPLMAATAAGLAPAIAAAAMSAAHVPLIANSTAQPIQRAEDLRAELIAQITAPVRWIATIEQAAAMGVQIVIEIGAGSVLTGLVKRIDPNLQRLNIANFDDIAKIAEYNNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN8</accession>
    <name>A9AXN8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0804</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0804"/>
    <dbReference type="EnsemblBacteria" id="ABX03452">
        <property type="protein sequence ID" value="ABX03452"/>
        <property type="gene ID" value="Haur_0804"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0804"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="LAEVWDW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-817-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="26978" checksum="B45ED7151A7C28DC" modified="2008-01-15" version="1">MSTILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDGFSVCRILRRETNIPIMMLTARQDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTDRQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFDLLVCLMRNRGMALSRDLLLERVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU7</accession>
    <name>A9AXU7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2273"/>
    <dbReference type="EnsemblBacteria" id="ABX04913">
        <property type="protein sequence ID" value="ABX04913"/>
        <property type="gene ID" value="Haur_2273"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2273"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_113_0_0"/>
    <dbReference type="OMA" id="LWATAFQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2301-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="672"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="895" mass="99166" checksum="9D081FDEB73B6A98" modified="2008-01-15" version="1">MEHQRPNPDQLLERIQSANQQAQRGRLKVFFGAAAGVGKTYAMLQAAQQRRAEGIDVLVGYIETHGRAETDALLVGLPQLPALQVEYRGTSLREFDLDAALERKPSLILVDELAHSNAPNLRHAKRWQDINELLHAGIDVYTTVNVQHLESLNDLVAQVTGVIVRETVPDAVLESADEVELIDLPPDELLGRLNEGKIYIASQAAQAARNFFRKGNLIALRELALRRTADRVDAQMQRYRHDHAIPTTWPTRERLLVGVGPSPLSERLVRATRRMANDLKAEWLVVYVETPKHLRLSEADRDRVTATLRLAESLGAQIVTLGGINPGEEMLRYARQRNVSKIVVGKPAQPRWRELLFGSIVDQLIRQSGEIDVYVISGEHDDTHKPNAKPSLQPHSPKINYVKSSGVVLACTMVCYGIFPHLELSNLIMLYLLGVTWVAARYGRGPAISASILSVAAFDFFFVQPYLTFAVSDVQYILTFMVMLIVALTISTLTVQIQAQAETARQRERRTAALYAMTREFASIRGLDNLLQTAAQHISSVFEGQTAILLPNPKGQLRPIVGQQWPFISDQRELITAQWVYDHQQKAGMHSDTLPSAQAMYLPLIATRGVVGVLALQPEQPRRLLDPSHVHLLETFANQTTVAIERAHLAEEAQAASVQIETERMRNSLLSSVSHDLRTPLAAISGAASTLLDQTNQLDQHIQHELIQTIADEGQRLNRLLSNLLDMTRLEAGAVQVHKEWQALEEVLGTALARLAPQIDQRSISIELPNQAFVPFDSILIEQVLVNLLENSLKYSPSSSPIEIRAVERIGLIEVQIADHGPGIPPSALETIFEKFFRVQAKRSASSGVGLGLTICRGIIEAHGGTIWAENRPAGGAIFAFTLPIEGQPPQIRGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-06-16" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY15</accession>
    <name>MIAA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="1">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="1">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="1">IPP transferase</shortName>
            <shortName evidence="1">IPPT</shortName>
            <shortName evidence="1">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">miaA</name>
        <name type="ordered locus">Haur_4265</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AY15"/>
    <dbReference type="SMR" id="A9AY15"/>
    <dbReference type="STRING" id="316274.Haur_4265"/>
    <dbReference type="EnsemblBacteria" id="ABX06897">
        <property type="protein sequence ID" value="ABX06897"/>
        <property type="gene ID" value="Haur_4265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4265"/>
    <dbReference type="eggNOG" id="COG0324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032616_0_1_0"/>
    <dbReference type="OMA" id="YAKRQYT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000377191" description="tRNA dimethylallyltransferase">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <sequence length="315" mass="35194" checksum="EF3693CC927C07BB" modified="2008-01-15" version="1">MQAPQPLIIAIVGPTAVGKTAFSLDLAQALNGEIVSVDSRLVYRGMDIGTAKPTPAEQALVKHHLIDVVNPDQEYSLATYQAAAYAAIAQIQQQAKQPILVGGTGQYMAALLEGWSIPEVAPNYELRARYEQQAASEGHAALHQQLQTIDPEAAKAIDPTNVRRVIRALEVFHETGQPISQLQQRNPPHYRILTLDLERPRDELYARIDQRVDLMMREGLIAEVWALIRQGYGWELPSMSGLGYAEFRPLWQGQQSAGACISQLKFNTHRFARKQGAWFRRLPKRVSLDARHTDLLAQVQELLAMPEHAPIHTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY64</accession>
    <name>A9AY64_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4314"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06946">
        <property type="protein sequence ID" value="ABX06946"/>
        <property type="gene ID" value="Haur_4314"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4314"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686572_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4366-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="44709" checksum="A7E026202850C99B" modified="2008-01-15" version="1">MTIDAAIIVVTYNHARYIGDCLSSLLALDPAPSELVVVDNASRDATAKIVKNQFPQVRFVQTGANLGFAGGCNQGARLTSAEYIVLANPDLIVQPDWLEQLIAPLERWPSVGAVGGKLLYRDGTTIQHAGGVLRLPWGLGHHRGVGEHDHGQYNALETVDYVTGAAFACRRSTWDVLDGLDEQFYPAYYEEVDFCTRLRRASLDVLYTPRAVATHIEGSSVGHRSAVYLQLYHFNRLRYLFKYFNNTWLMRTWLPAEMGHIRACASDDEIQALKIAYLAYQSAFLNHESQPVISELDIFPDETADGGETELQWIERQLRAKVKVEPAPIPARQRWLGAIRNGLLRLATRDFIVPIVQAQNDTNAALLESIQALSRQRRAADATILLQGMLLAKSLDQQPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB1</accession>
    <name>A9AYB1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4388 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0845"/>
    <dbReference type="EnsemblBacteria" id="ABX03493">
        <property type="protein sequence ID" value="ABX03493"/>
        <property type="gene ID" value="Haur_0845"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0845"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1007014_0_0_0"/>
    <dbReference type="OMA" id="LIMYLAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-859-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4388" evidence="1">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="30413" checksum="E720C128EDD7F9B8" modified="2008-01-15" version="1">MALVGNLRDFALADFLYLIDRGYKTGSLQLNRQSAAATLYFEKGKLLYAAQTQERESLGEMLQRTGKLTPQQAQQAVQLQQTDGNQSLGTVLIDSDILTREDLQRHIQTHIEETVYSLFGWPDGEFCFNAGVKLDRDDVQSLVPLGVENLIMEGVRRVDEWGRIKDHIPNTDMIARFVDQPLEKAKSINLTPDEWRIFARINGKDSIKEVISRTGLSEFDVSRIVYGFISAGLVEVTRPRPPVPATGRAGAGAAAGAPKRSLVSRIINRIRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI7</accession>
    <name>A9AYI7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0921"/>
    <dbReference type="EnsemblBacteria" id="ABX03569">
        <property type="protein sequence ID" value="ABX03569"/>
        <property type="gene ID" value="Haur_0921"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0921"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053105_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-935-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="398" mass="45458" checksum="7D83C2034CC00C81" modified="2008-01-15" version="1">MTNPALTLNDFAALEASTDYRPHVVDDVQVSPFSQQQTNQYVVGRPASPSFMRTNVVGVRILELLNGQRSIEQLQTEMQQRYGIEVSIEKIRHFCDLCARHRLLVHETWANTTPDSEDAPRLGRRSGFYWTLIRGDSFIERIVAWQRWWWNPVTWLLMLGLLGVGLTYIVTKGVMLVSPLMLAHPDASKHLIFWLFGLFLVEIATHELAHAVACRMAGAKPAGFGMGLLWWFIPIFFTDTSDIYRVPSKYRRASVAAAGPLVDALWFGVVASLLWLLPRDSLAYEIAFAYSGIPALLCLINLNPFVSRMDGYWIITNLLEQPNLRRRTVRNIVNNIRGWFGAAPIIDPLSEQQSGRWQWAYNMYALVSLLWTVFFMFNIGFHFASYGFTILRMYAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL0</accession>
    <name>A9AYL0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2348"/>
    <dbReference type="EnsemblBacteria" id="ABX04988">
        <property type="protein sequence ID" value="ABX04988"/>
        <property type="gene ID" value="Haur_2348"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2348"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_3_1_0"/>
    <dbReference type="OMA" id="NQFHYFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2376-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="31"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="44840" checksum="53C58D2201FEEA58" modified="2008-01-15" version="1">MDLHSGYPFWAVKNGLLNIYPRLQNDLTCEVVVIGGGISGALIAHYLSEANIDTVVLEKRELAGGSTSASTALLQYEIDTPLTELVKLVGEQQAVRAYHLCREAIDKVADLAQKVGVADHFSYKTSLYLASSRWHVKQLRQEFALRQAHGFKLDLLDKAAIGERFSFTAPAALYSYSAGEVDAFQLSHALFKQAAQRGVQIFDRTVAKEWQSNSDGVTVTTETGYRIHAKYLILAAGYEAQHYIKPKLVKFRSSYALASEPLTDFSGWYERCLIWESARPYVYLRTTNEGRAIIGGEDDQIDLPAKRDALLERKAAKLTKRFNQLFPQIPLHVDYRWAGTFGETKDGLPYIDNLPDQPRILLALGYGGNGITYSVVAAELLRDRVCQRANPDAAIFRLDRN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYL1</accession>
    <name>MTNA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="1">M1Pi</shortName>
            <shortName evidence="1">MTR-1-P isomerase</shortName>
            <ecNumber evidence="1">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtnA</name>
        <name type="ordered locus">Haur_2349</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="ABX04989" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04989.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYL1"/>
    <dbReference type="SMR" id="A9AYL1"/>
    <dbReference type="STRING" id="316274.Haur_2349"/>
    <dbReference type="EnsemblBacteria" id="ABX04989">
        <property type="protein sequence ID" value="ABX04989"/>
        <property type="gene ID" value="Haur_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2349"/>
    <dbReference type="eggNOG" id="COG0182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_1_2_0"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000357196" description="Methylthioribose-1-phosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="248"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="355" mass="37909" checksum="CDA16FD9AAD2CDDF" modified="2008-12-16" version="2">MADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLEKLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQLRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTHCNAGGLATAAYGTALAPIRAVHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGSDRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTHIGQQAIAAAGIKVAHPAFDVTPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS9</accession>
    <name>A9AYS9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oleoyl-(Acyl-carrier-protein) hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2417"/>
    <dbReference type="EnsemblBacteria" id="ABX05057">
        <property type="protein sequence ID" value="ABX05057"/>
        <property type="gene ID" value="Haur_2417"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2417"/>
    <dbReference type="eggNOG" id="COG3208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070456_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2445-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016295">
        <property type="term" value="F:myristoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004320">
        <property type="term" value="F:oleoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016296">
        <property type="term" value="F:palmitoyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="256" mass="29357" checksum="7A6A34AE54D62803" modified="2008-01-15" version="1">MKLPLWIEWLRKQPNAALRLFCFHYAGGTAQRAHQWTQQLAADVEICAVELPGRGKRFMEPAYTRIEHVLDDLIPAIKPLLEEKPFAFFGHSMGTLVSYELSRRLQRDHQLSPQVLLVSGHAAPHIPRQSVIHQLPDQQFWDRLIQLNGTPKEVLQHPELLDLLTPILRADFAVCETYVYSDSLVLDCPMVVYGGQDDPSVAAEQLELWRNHTSNECLVQIMAGDHFYLHNPSQHELQQHVNQQLQLVLSSVNLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYT0</accession>
    <name>A9AYT0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase, MGT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2418"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05058">
        <property type="protein sequence ID" value="ABX05058"/>
        <property type="gene ID" value="Haur_2418"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2418"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_7_0_0"/>
    <dbReference type="OMA" id="LVIMPAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2446-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="397" mass="44004" checksum="D214BFE70A26B1CD" modified="2008-01-15" version="1">MRALFVLNPGIGHLNPMLPVAQILQEAGHDLAFATSPKMLPSINAKGFNTFAAGLNWLSSEMDQTFPEIFELPFAEQGQAILGSIFADAAAHPMVADLLNICQTWQPDLIVRNDFEFGSCVAAEILGIPQATISISYFLSANALESLIGEELAYLRSTYGLAPYPTMDMLYPSLYLAFAPPSFQPKEIPTMESLRPLRFTRFSDGDLPAWVSQLPDRPTVYASMSSVFDTPTIFPMILEALRDEPINLILTVGTKQDPAQFGPQPANVYIEQYIPQALLFPYCDLFITHCPFATIMAAISHGMPLLMIPVAGEEPAGAMRAAELGLGKVLRLPNQPKEFFDQWVPEFSVESIRASVRELLQTTRYRNNAQRFQAEIQALPGPERVIELLTNLAHKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU7</accession>
    <name>A9AYU7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4355"/>
    <dbReference type="EnsemblBacteria" id="ABX06987">
        <property type="protein sequence ID" value="ABX06987"/>
        <property type="gene ID" value="Haur_4355"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4355"/>
    <dbReference type="eggNOG" id="ENOG5032BV2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_823291_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4408-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735341" evidence="2">
        <location>
            <begin position="26"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37423" checksum="BD2A32FCB3DCED4C" modified="2008-01-15" version="1">MHRYSRLMLILGLALLSACSNSSPATIQPLPEQPTASIPAANPDQPTSTPAVSQTAVSEDNSAPPSPPNLPAFDDRQDPLSLLASFYNAINRADYQRAYGYFEVAPMPFDQFEQGYEQTLSVKVLIDPHFVIDVGAGNQNTRVAAGLIAYDRQAGWQYFVGCYELHRVNINGPTEPWQIRNSQFELTNDLQAMSQQLGQICPAIEPPARVQTPEQTLALYISTLNQANYAQAWNYWHEQPASDVAAWSQQFESNQFIQVVINPQGLIDAGAGNLYYSTNLVWLTNDQAGQLQVQAGCVTLHRNNTEPDQPWKMQNLTLQTLQANPRALDQSLNNQCQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX1</accession>
    <name>APT_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="1">APRT</shortName>
            <ecNumber evidence="1">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">apt</name>
        <name type="ordered locus">Haur_4379</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYX1"/>
    <dbReference type="SMR" id="A9AYX1"/>
    <dbReference type="STRING" id="316274.Haur_4379"/>
    <dbReference type="EnsemblBacteria" id="ABX07011">
        <property type="protein sequence ID" value="ABX07011"/>
        <property type="gene ID" value="Haur_4379"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4379"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063339_3_0_0"/>
    <dbReference type="OMA" id="KPGIVFR"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00103">
        <property type="entry name" value="PUR_PYR_PR_TRANSFER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0660">Purine salvage</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000116246" description="Adenine phosphoribosyltransferase">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <sequence length="172" mass="18699" checksum="C7D4E10196D5AE70" modified="2008-01-15" version="1">MSLDLTQFVRNIPDFPIPGVQFKDITPLLGNAQAFDAAIEHFAQRYANQQLQAIVGIESRGFIFGAPLALRLGIGFVPIRKPGKLPAQTIGVDYSLEYGTNRLEIHNDALQAGDRVVVVDDLLATGGTVVAACDLLNQLGAEVVEAAFLIELTFLGGREKLGNRPFYAQIQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX7</accession>
    <name>A9AYX7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4385"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07017">
        <property type="protein sequence ID" value="ABX07017"/>
        <property type="gene ID" value="Haur_4385"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4385"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_0_0"/>
    <dbReference type="OMA" id="WSQPTVG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4439-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="378" mass="42625" checksum="C6035773E3B7A107" modified="2008-01-15" version="1">MRIGISGTFWAEPMVGSGQYLHHLIEHLPHVGPQHEYVLFLPAYTQAEIPQIPHIAVDRVPTPFDKLHPKLAKLWYEQIELPRAALRLAVDLLHVPYYAPPRRQLVPTVVTVHDIIPLILPEYRGSLAMRAYTALATSAVRRCRQLVAVSDHTRDDIIDVLNINALHVHTIYEGVAPDYQPQTDEQISQTLQRFNLNQPYFYYIGGFDVRKNLTTLLRAFGRVRRRIEQPIKLVIAGSRPKANSPFFPALETTILDEDLAADIIFTGRVTNAENAALFAGASAFVWPSTYEGFGLPPLEAMSCGTPVISSNTSSMPEIVGEAGILLPPHDTEAWAMAMLRMLNDAELNNEYRQRGLQRASQFNWQHFTAQMLKVYEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY0</accession>
    <name>A9AYY0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4388</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4388"/>
    <dbReference type="EnsemblBacteria" id="ABX07020">
        <property type="protein sequence ID" value="ABX07020"/>
        <property type="gene ID" value="Haur_4388"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4388"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_0"/>
    <dbReference type="OMA" id="DIIMGCV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4442-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="262"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="384" mass="41060" checksum="41B51898250249F5" modified="2008-01-15" version="1">MAEAVLIDAVRTPIGRQQGSLRDVRPDVLYAHVLNTLIERTGIDPNLIEDVVTGCVTNTGEQGANIGRLGVMLSNLPITVPAVTLNRMCGSAQQAIHFAAQAIAAGDVSYAIAGGVESMSRVPMFSDVTGNFATFNPAINEKYQLVHQGESAELIAEKYQLSRTELDDWSFESHQRAAAATKAGWFSSQLAPIVGSDKTGNPHELIYDEGIRFEADRAKMGTLKTVFRADGVVTAANASQISDGAAVVLIGEREQALADGFKPRAKFRARVVAAGDPRMQLLEVIPATHKALAKAGLSINDIDLVEINEAFASVVLAWLREFKLDPSRVNPNGGAIAHGHPLGATGAVLMSKMINELERRDAQFGLQVMCIGHGQATATIIERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY3</accession>
    <name>A9AYY3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4391"/>
    <dbReference type="EnsemblBacteria" id="ABX07023">
        <property type="protein sequence ID" value="ABX07023"/>
        <property type="gene ID" value="Haur_4391"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4391"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_0"/>
    <dbReference type="OMA" id="AMEELFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4445-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="121"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="228"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="42268" checksum="22FDDF57673F2E59" modified="2008-01-15" version="1">MELNEELRMLRETVRDFAVKEIKPIAREVDEAERVPFETIRKAGNLGLLGIPFPEEYGGADAGIVGYCILQEEINRYCASTGTIIGAHAQLCGMSIFLSGNDEQKSRYLSKLNEGKLLGAWALTEPNAGSDAASITTTATQDGDDWIINGGKMWITNGSFADVIVVFASTNRERGARGGISAFIVEKDFAGFKVGKVEEKMGLRASHTASIFFENCRVPAKNVLGEIGAGFGVAMKTLDIGRCGLGASALGSAKEAYDLALHYSVERQQFGRPIADFQAIQIKLAEMRTKIYAMEQMVYHCAALVDAKKPATLESSMVKLFCTEAASQIIDEAIQIYGGMGFSREVPLERMYRDARVTRIFEGTNEIQKYVIAGEELKKLGHKIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ98</accession>
    <name>A9AZ98_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransf_33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0996"/>
    <dbReference type="EnsemblBacteria" id="ABX03644">
        <property type="protein sequence ID" value="ABX03644"/>
        <property type="gene ID" value="Haur_0996"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0996"/>
    <dbReference type="eggNOG" id="COG4301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049766_1_1_0"/>
    <dbReference type="OMA" id="RVEMHLV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1012-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="22"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="36577" checksum="7F435BBDB3E7CF28" modified="2008-01-15" version="1">MSETQQVAKVRLLDAAPTIACFRSEVLEGLRQPIKTLPCKFFYDAEGSQIFDAICELAEYYPTRTELAILQQAMPAIRHWVGPDVRLVEYGSGASRKTRLLLDQLEAPAAYLPIDISREHLLAASQDLAERYPAIEILPICADYTQPLSLPQAQRSVGRTVVFYPGSTIGNFHPDEALSFLTMMRELCLPDGGVLLGVDLKKDPSLLHAAYNDTAGVTAAFNLNLLARINRELDANFALANFRHYACYNPIQGRIEMHLVSLHDQTVWIGDQQIDFRRGEPIWTECSYKYHLQEFAALAAQAQLAVAEVWTDPQNLFSVHYLRPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI6</accession>
    <name>A9AZI6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05130">
        <property type="protein sequence ID" value="ABX05130"/>
        <property type="gene ID" value="Haur_2492"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2492"/>
    <dbReference type="eggNOG" id="ENOG5032SFE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129219_0_0_0"/>
    <dbReference type="OMA" id="MRHVQHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2520-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="168" mass="19285" checksum="D89D30E622D6BF66" modified="2008-01-15" version="1">MESIWKTSVWQQFGAAIAMLEDPIVRCPDQLWTSVLWEDPDDPRYGHFWFVAYHSLFWLDLFLTGSSEGFKPPAPFVRGSLPDQPYSKAQVLAYLHDCRQRCKATIMGLTDAKAQERCIFEWMQPSFFELQLYSMRHVQEHAAQLSLALGQQGIAGADWIAQAIDNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI8</accession>
    <name>A9AZI8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A9AZI8"/>
    <dbReference type="STRING" id="316274.Haur_2494"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05132">
        <property type="protein sequence ID" value="ABX05132"/>
        <property type="gene ID" value="Haur_2494"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2494"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_13_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2522-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009470">
        <property type="entry name" value="Chi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06483">
        <property type="entry name" value="ChiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732276" evidence="5">
        <location>
            <begin position="38"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="76"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="712"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="826"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="904" mass="97731" checksum="F5E293755798BFC3" modified="2008-01-15" version="1">MNVAYRRTAKLRGAFSLTITLALLAGMLLTRGTPTQAAGNADCRPDGMAPTAGVDTPYCAIYDTAGREKMGSDHPRRIIGYFPSWRTGTNGQPAYLVNNIPWNKITHINYAFAHIQNSRISVGSNTATNPSIGMTWPGVAGAEMDPALPYKGHFNLLTQYKRQNPNVKTLISVGGWAETGGYFGDNGDRISDGGFFSLTVNADNSVNTAGINTFADSVVGFLRSYNFNGVDIDYEYPTSMKDAGHPLDWVYANPRRASLMKGYVVLMKTLREKLDVAGAADGKYYMLTIASPSSGYLLRGMETYQVTQYLDYVNVMSYDLHGAWNEYVGPNAALYDDGTDAELAAAGVYTTAQYGGIGYLNTDWSYHYFRGSMPAGRINIGVPYYTRGFKNVTGGTNGLWGKAVGSNCPIGLTKCGDGARGIDNIWHDIENGQEVGAGANPMWHAKNLEQGLAGSYISQFGLNPATDPEDRLTGTYVRHYSSSLVAPWLWNSQKRVFISTEDEQSLGAKADYVVNKGLGGIMFWELSGDYDWHADRNNGQGEYFMGDTMTSLLYDKFRNAPAYGANKSNRTLPSNLLDIKVDFTNWPIGDNNYPISPKMVITNNSNVTIPGGATFEFDYGTSAPNNAKDQSGFGFTVTSSGHTGNNVGGLRGDFNHIQFKFPGWQSLAPGASVTIDFVYYLPMSTPSNWTVNFGGTTYGLVSDYPRGNVVVPTPTVGNPTNTAVPPTNTPRPTNTPVGPTSTPTRTPIATATNTPAPSATPTQPGTCTAPAWESNKIYVRGDVVSYNNHHWFAQWWTQNETPGNAQVWLDQGLCGGGNPTNTPVVPATSTPRPTNTPVVPPTNTPVQPSATPTNTTGVQPWAAYVSYAAGAKVSYNGVTYTCLQPHTSLPGWEPSNVPALWRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL6</accession>
    <name>A9AZL6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Cytochrome P450</fullName>
                <ecNumber evidence="8">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="8">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_2522</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>NADPH + 2 oxidized [cytochrome P450] = H(+) + NADP(+) + 2 reduced [cytochrome P450]</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="8"/>
    <dbReference type="EC" id="1.6.2.4" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2522"/>
    <dbReference type="EnsemblBacteria" id="ABX05160">
        <property type="protein sequence ID" value="ABX05160"/>
        <property type="gene ID" value="Haur_2522"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2522"/>
    <dbReference type="eggNOG" id="COG0369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_0"/>
    <dbReference type="OMA" id="WKKAHNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2550-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 8" id="KW-0288">FMN</keyword>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="10">
        <location>
            <begin position="487"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="662"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1053" mass="117543" checksum="D05A7F6FE474A8DF" modified="2008-01-15" version="1">MSISSPIRYIPQPPTRPIVGNVPDIGMETPVQNLMKLAQHYGPIFRVSFPNRSVLVVSSAELVAEISDQQRFDKLLHGPLIQIRDFAGDGLFTAYTEEANWSKAHRLLMPAFGPASMRNYFDDMLDIADQLFTKWERQGPETDFDVADNMTRLTLDTIALCGFGYRFNSFYQREMHPFVEAMVRALAEAGARARRLSIQTKLMRSTQRQYEADMQYMHGITDELIAKRRSLPSNEVPNDLLGLMLNAKDSITGEGLDDANIRNQLVTFLIAGHETTSGLLSFATYFLLQQPEILQRAQAIVDQVLGDRLPRYEDLAKLGYLDQILRETLRLWPTAPVFGVYAKHDTNIGGFPIKQGEKFIALLPTLHRDPKVWLNPNQFDPDRFAPEVREQIPEHAWKPFGNGQRACIGRSFAMQEASLVLAMMLQRFELSQPQPYQLHVKETLTLKPEGLTVRARVRKNIVRSTKPTQPNVAIQSNPNQAQHNIPLLVLYGSNSGSSEAFARRIASDGEARGYQTSVAALNNYVNKLPTTGAVSIVAASYNGQPADNAQAFCQWLAGVEPNSLKGVRYSVFGCGNRDWQSTYQAVPTQIDQHLQAAGAERLLQRGAADARSDFFGDFERWYAPFWQTHNQTFAIASAEINSKPLYKVELLPSSSDQLAQQTGFMFASVLENRELVDLSSPLGRSKRHIELRLPNELQYQAGDYLAILPQNHPSLIERACKHFGLKPEQTIILHATRGAANLPIDRPISLGELLSSHVELATPATQRDLELLAQKNVCPSHQIHLAALAADHERYTTEILQKRLSLLDMLEQYPSSVLDFGEFLELLPAMRVRQYSISSSSLVNPNQASLTVAVVDAPAWSGKGQFYGTGSSYLARLQVGDQIAVSLRQPHIPFRPPSANSTPLLMICAGTGLAPFRGFIQERVARQGQGEALGPNALFFGCDHPEVDLLYHEQIQAWQKAGVLEFFPAFYRQPVGEVSFVQHRLWQERQYVWSLIEQGAVIAVCGDGRSMAPAVRETLARIYAEATGSEQTAGMAWIAEIEQAGRYVADVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZX5</accession>
    <name>A9AZX5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1034"/>
    <dbReference type="EnsemblBacteria" id="ABX03682">
        <property type="protein sequence ID" value="ABX03682"/>
        <property type="gene ID" value="Haur_1034"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1034"/>
    <dbReference type="eggNOG" id="COG1682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060703_3_0_0"/>
    <dbReference type="OMA" id="GFAWFQK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1051-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="36"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="31824" checksum="397385087810A486" modified="2008-01-15" version="1">MQRASTTLQTTPITRIEPSKGWVSLQLRELWAYRELLFFLIWRDVKVRYKQTVLGAAWAIIQPVFSMIVFTLIFGRLAKLPSDGIAYEAFSITALVPWALFANALSQGSNSLVGNANLIKKVYFPRLTVPISTVLGGLVDFAIAFVVMFGMLLWFGITPSIRMLALPLFIMLVLITGLGVSLWLAALNVQFRDIRYVIPFMAQLWQYGSPVAYSSSLIPQEWRWLYGLNPMVGVIDGFRWSMLGTGQISWSSMLPSVGIALFLLFTGALYFRRIEKQFADMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B012</accession>
    <name>A9B012_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1071"/>
    <dbReference type="EnsemblBacteria" id="ABX03719">
        <property type="protein sequence ID" value="ABX03719"/>
        <property type="gene ID" value="Haur_1071"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1071"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_0_3_0"/>
    <dbReference type="OMA" id="AWIDRYR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1088-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="13007" checksum="43DFF9F1131EA97A" modified="2008-01-15" version="1">MARAATTTDVFNAIAEPGRRQILDLLVNGELSVNELVEQLGLAQPQVSKRLHVLREVGLVLVRDDGRQRYYRLNGRALKPIHDWIRRYEQMWNERFDALDELLEELNHEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B029</accession>
    <name>A9B029_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1088"/>
    <dbReference type="EnsemblBacteria" id="ABX03736">
        <property type="protein sequence ID" value="ABX03736"/>
        <property type="gene ID" value="Haur_1088"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1088"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1407562_0_0_0"/>
    <dbReference type="OMA" id="GLTVMQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1108-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="190" mass="20079" checksum="70E59708A43123A2" modified="2008-01-15" version="1">MSTSIAFALFFVLLSPILTAILLRFLRTRLSALPFYSIAGVLFGLAAVAAIWLVSQHQANVQLGSLVLIQQQGIDLEVPPEAEPTAMPTQVLPTLAATATRLAPTATTRPSATPTAEPTATTEATAEPTATSEPSATPTAERRTYTVEDGDTLRSIAEAFDVTIAELLEANDLTPQQADQLQPGDVLIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B087</accession>
    <name>A9B087_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2558"/>
    <dbReference type="EnsemblBacteria" id="ABX05196">
        <property type="protein sequence ID" value="ABX05196"/>
        <property type="gene ID" value="Haur_2558"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2558"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1228533_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2586-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="61"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="24860" checksum="85A11F4E286E5BAE" modified="2008-01-15" version="1">MKRFLAGLRPLIQQLPYKFPRAYDLLVHHGIFRWLGMAGSEQTALVAKALQHEGWAIEAPIGTGRLTIDLYAQRPNLQVVGIDLAMPMLRTAQAELAKKGIINVHLICADMTALPFHADQFIQIVTLNGLQVVPHAETLIDELLRVAEDGCAIAGAATVDIGLEPRGGVQRLLVRSGMINKLNPEQLHEIISLTWSKLSANRRGAVYNFLRPRLDRATGEPIVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A4</accession>
    <name>A9B0A4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 9">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_2575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2575"/>
    <dbReference type="EnsemblBacteria" id="ABX05213">
        <property type="protein sequence ID" value="ABX05213"/>
        <property type="gene ID" value="Haur_2575"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2575"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_3_0_0"/>
    <dbReference type="OMA" id="RGSIQNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2603-MON"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="10">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="806" mass="89564" checksum="B6C2F93E4D8D610B" modified="2008-01-15" version="1">MNEIEVGASASPEQAPWLYQLIVEACAAYPQTTDANTLWQAASLGFYPNMAVAEQLQACCLTARSWIEQEPDYSFVAAALLASQLHFEVLGEYLATPAVVPRYASAFVDYIQAGIAQGLLDPKLASFDLARLAAAIVPERDALLAYPGLQTLYDRYFIQWQGLRRELPQIFWMRVAMGLALNEADREAQTLRFYEVLSQFHFTSATPTLFNAATTHPQLSSCYLSTVGDDLEAIFGAISDNAMLSKWAGGLGNDWTPVRALGAPIHGTNGVSQGVIPFLKIVNDTAIAVNQGGKRKGAVCAYLEAWHADLEDFLDLRKPTGDERRRTHDMHTALWVPDLLMERVLSNGSWSLFSPDEVPDLHDLYGQDFAVRYAEYEALAAQGLMRSARQVEAVALWRKVLTRLFETGHPWITWKDAANVRSPQDHVGVIHSSNLCTEILLNTSADEIAVCNLGSINLAAHIRDGSLDLEKLRTTVTTAVRMLDNVIDINFYPRPQAAQANARHRPIGLGLMGFQDALYALKIGYASQAAVEFSDRSMEAIAYFAVAASIELARERGAYPSFRGSKWDRGMLPIDSLAILAEQRDSKPELDHSSHYDWQPLREALAQYGIRNSNLLAIAPTATIANIVGTSQSIEPTYRHLYVKSNLSGDFTTVNRALVDALKARGLWDVDLLAELKYYDGAISQIERIPAELKTQFLTAFEIAPEWLIACAARRQKWIDMGQSLNLYVAETSGKRLNEIYLTAWRMGLKTTYYLRTLAATQIEKSTLDINRFGVQPRWMRNRSESASVLSDNVCPIDDPSCEACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G7</accession>
    <name>A9B0G7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylornithine and succinylornithine aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4554</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4554"/>
    <dbReference type="EnsemblBacteria" id="ABX07185">
        <property type="protein sequence ID" value="ABX07185"/>
        <property type="gene ID" value="Haur_4554"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4554"/>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_0"/>
    <dbReference type="OMA" id="PFMVPTY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4609-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="404" mass="43022" checksum="8E61F1BCCFEDC6E1" modified="2008-01-15" version="1">MTQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGDAEVVAAIQQAATGLLHTSNLYYTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFARRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRTPFNPLIPGVRFINLECDQATLEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDVWAHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVVLQKVTHPTMLDHVRSVGAELGAGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAAFDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAISQVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H7</accession>
    <name>A9B0H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4564"/>
    <dbReference type="EnsemblBacteria" id="ABX07195">
        <property type="protein sequence ID" value="ABX07195"/>
        <property type="gene ID" value="Haur_4564"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4564"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_0"/>
    <dbReference type="OMA" id="LWYSVQS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4619-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="108"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="38700" checksum="F1EABE36C8F9B7C2" modified="2008-01-15" version="1">MASAESSVERASDSAIPRPSWWARTRTSRTAYTYLFPALIVMSIITFYPILYQFWMSLTDFGPSSINPLAKNYTPPKYVGFENYQLILQDKLATKNADLASFKFWRTLGFNIWWTFSNVIFHVSLGIVIAVMLNVEGLWFKKIYRAIYILPMVLPQLVIATIWRNMFDGQYGAINLMLKIFLGPAFPSGGIDWLQRIEPVAFGLPLSYFAMLIANIWLGWPFMTIVATGALQSIPKELYEAASIDGATGWNKFWTITLPLLRPAMVPATILGIIQTFNLFHVIYFISGGGPLGQTEILVTQAYKLINNNSLFGIGAAFSVFIFIILGCISAITARISRVAESYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K7</accession>
    <name>A9B0K7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ordered locus">Haur_4594</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4594"/>
    <dbReference type="EnsemblBacteria" id="ABX07225">
        <property type="protein sequence ID" value="ABX07225"/>
        <property type="gene ID" value="Haur_4594"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4594"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_0"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="299"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="413"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="428" mass="46667" checksum="F52D2D91760C68EF" modified="2008-01-15" version="1">MPVVAVLGAQWGDEGKGRVVDLLATKAKMVIRAAGGSNAGHTVINHLGTFKLHLTPAGIFDANVVNIIGAGTVIDPAVLMKELQALREANVSLDQLYISDRAHVVMPYHVSLDALEEKDRGANEIGTTKRGIGPAYVDKASRMGIRMGDLLHEETLLSRLTSVLEYKGRVLNKMYGAQPSASLHDMYLQYLEFGRQLEAHIVPIHTMVQDALRRDIPILIEGNQGALLDVDYGTFPYVTSTATGSAGACQGAGIPPMRLNGVVGIYKAYTTRVGGGPFPTELTDELGEYIRQAGHEFGTTTGRPRRVGWFDAVAARYAAEINGISSIALTKLDVLDDVETLKICTGYRWNDTELDSFPSSISVLSQVEPIYEEYPGWKTNTSHARTLDELPEAAQRYVRRLSQLVGVRLGMISVGPSREQMVSLQEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T4</accession>
    <name>A9B0T4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1156"/>
    <dbReference type="EnsemblBacteria" id="ABX03804">
        <property type="protein sequence ID" value="ABX03804"/>
        <property type="gene ID" value="Haur_1156"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1156"/>
    <dbReference type="eggNOG" id="COG1268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077931_2_0_0"/>
    <dbReference type="OMA" id="AGYLWSY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1178-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="21280" checksum="495D6D3DCC6AC00A" modified="2008-01-15" version="1">MYRVESVAERQTLADLIRGKSLGRDLALIIGFSLFVALTAQIAIPLPWTPVPITGQTLGVLLTGAILGPRRGALAILLYLVEGLAGMPVFAGMTSGLAKLLGPTGGYLLSWPLAAALVGWLAQRGWDRRIPTALAMFCFGNILIYAIGASWLNIYKDTFGQISVMWAGVYPFLPGDALKIVIAALVLPGAWALFGRNER</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X2</accession>
    <name>FPG_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="2">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="2">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="2">AP lyase MutM</shortName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mutM</name>
        <name evidence="2" type="synonym">fpg</name>
        <name type="ordered locus">Haur_1194</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="2"/>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B0X2"/>
    <dbReference type="SMR" id="A9B0X2"/>
    <dbReference type="STRING" id="316274.Haur_1194"/>
    <dbReference type="EnsemblBacteria" id="ABX03842">
        <property type="protein sequence ID" value="ABX03842"/>
        <property type="gene ID" value="Haur_1194"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1194"/>
    <dbReference type="eggNOG" id="COG0266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038423_1_2_0"/>
    <dbReference type="OMA" id="GVHLRMT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="initiator methionine" description="Removed" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_1000094049" description="Formamidopyrimidine-DNA glycosylase">
        <location>
            <begin position="2"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="FPG-type" evidence="2">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <sequence length="273" mass="30800" checksum="37CB7732C7B62BFE" modified="2008-01-15" version="1">MPELPEVETVRRSLEQELVGRYFVALRSLGWPKIVDTHSPELFAEAIAQRQIQQVQRRAKYLLIELDNHETLIVHLRMTGQMLVVAADEPADRHTHVVVALDNGRELRFHDPRKFGRWSLVDRSGVAALNQRLGPEPLGDDFTLDDFAQRLSRKATKIKPTLLDQSVLAGVGNIYADEALWLAKIHPLRSANSLNANEIAELFEAIKTVLRNSIEHRGTTLVNYRDAYGASGENQYHLEAYGRTGEPCRRCGTPIERIVVAQRSTHICPVCQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B172</accession>
    <name>A9B172_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclic nucleotide-regulated small mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2712</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2712"/>
    <dbReference type="EnsemblBacteria" id="ABX05350">
        <property type="protein sequence ID" value="ABX05350"/>
        <property type="gene ID" value="Haur_2712"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2712"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032479_3_0_0"/>
    <dbReference type="OMA" id="NWRATHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2743-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
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    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
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    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="5">
        <location>
            <begin position="347"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="507" mass="57214" checksum="EFB22F36ABD8616F" modified="2008-01-15" version="1">MLSVIEHIIQPMLWAIGTYAVLRLLIRLGRRIGLISGLSILGQFLALSSAGLIGLWSDQQLEHWPLLTKILQTTVTVSIIAVVLHIGDQLLVRRLAADGRPNAIPRLMRDIARGFVLLMTLLICIGHFFKVQIGTVLLSSTVFTAVVGLALQDLLKNVIAGIALQMERPFMPGDWIFIDVQTGYGRVLEMSWRAIRVKPRDGQVVVIPNTIIAQQQIINMSATGLPVAMRVAVTVDCVHPPMMVRELLKEAVLSSRGVVAQPEPFVFVRNYTAFSTTYEVKCWISNYDDFPQLQGDALSRIWYVFQRQGIHFASNEMVLTRPEQASRQRRLDYTPEQIFDRLRRIKLLDGLHEQELRFLSEHVEIRLFERGEILAHQGRHEHILYAITRGKVRVEVAHDDQPAIVVSHLGAGDVFGERGMLMDEPRSASVIAEEDTRTIVIERHDLAPLYAKNPSLAERLGVMVAERQQATHNYLEQQRSVNQNPTPSPAARSITERIRDVLLDLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B175</accession>
    <name>A9B175_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2715"/>
    <dbReference type="EnsemblBacteria" id="ABX05353">
        <property type="protein sequence ID" value="ABX05353"/>
        <property type="gene ID" value="Haur_2715"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2715"/>
    <dbReference type="eggNOG" id="COG3693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037113_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2746-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735172" evidence="2">
        <location>
            <begin position="23"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="562" mass="59187" checksum="B350B0E9EAA20BE9" modified="2008-01-15" version="1">MNNRRLALLVSLCAVLLGFAVAKRPEVTSAKALLTPTPTPLRSELILSGPTEVQVGQLFTITIQYVNIGLPYTTITMSPNNLAQFDPPMTMPCKYNEHPTGCQSITLRATTGGMLEIFASATGEVPIAGGGWAWGSAQARNPIWIDVIDPNATATPTPMPTCVPATRTPTSTMLPTYTPTPAGQATATPTPTKTRTPTPTALPCQQTSYAELLLSAPSQVRVGDVFTLTIDYVNIGAPDTGISLSPNGLAQVEAPSVMPCDFFEDPTHCTKIRLRATAVGELTIDAWATGELFIDGGWMWGGARARNPVYVNIVAGDGTPTFTPTPTKTGTPTPTFPSYPCYTPTTRPIQKQAPQVTQAPCTPTPTSTATPTFPSAPCFTPTAQPLNSNRVQTTQVPCTPTPTATKTATPCPTNLAMRGSTCIGTPTITPNRGSPTITPIVSELILSAPPLVNVGDAFSLTIQYVNIGVPYTGITLSPTGTVQFDPPLTMPCKFNEHPTDCRTIGLRAVAPGTITINAGANGEVPISGGGWAWGSAHARNPINVQVRSVLAHKAFIPFVKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B184</accession>
    <name>A9B184_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endodeoxyribonuclease RusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07271">
        <property type="protein sequence ID" value="ABX07271"/>
        <property type="gene ID" value="Haur_4640"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4640"/>
    <dbReference type="eggNOG" id="COG4570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1852450_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4697-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008822">
        <property type="entry name" value="Endonuclease_RusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036614">
        <property type="entry name" value="RusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05866">
        <property type="entry name" value="RusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103084">
        <property type="entry name" value="SSF103084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="16010" checksum="347182215783E28F" modified="2008-01-15" version="1">MVVQFSLPLPPSINSQYVTVGNRRVLSREAQAFKRQVKRQLALLQQRDTISEQFLALAHQGYIALFLDFYFETPLRRDLDGGLKITQDSICTSLGINDNRVVDIHLVKRIDPLHPRLEVELEALSDWQFEHDRQVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1C4</accession>
    <name>A9B1C4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine-specific ribonuclease N1 and T1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4680"/>
    <dbReference type="EnsemblBacteria" id="ABX07311">
        <property type="protein sequence ID" value="ABX07311"/>
        <property type="gene ID" value="Haur_4680"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4680"/>
    <dbReference type="eggNOG" id="COG4290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1347379_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4737-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="22381" checksum="E3D3A1C955C071F0" modified="2008-01-15" version="1">MSTRLRRGLEFGLGLIILIGLIWFNNLPSSDQPTPSPNPSATIEISSRGLPSSTPQQATSRPRQTAVATAKPTTRPRQTVMPTAKPTTRPRPSPTVAPTARATRTPERDSAGLRYVAFGDLPIQAQATIRLIEQGGPFPYSKDGAIFNNREQILPSKPRGYYREYTVETPGSADRGARRIVAGDNGELYYTDDHYASFRRVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1E7</accession>
    <name>A9B1E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07334">
        <property type="protein sequence ID" value="ABX07334"/>
        <property type="gene ID" value="Haur_4703"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4703"/>
    <dbReference type="HOGENOM" id="CLU_1254504_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4760-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="23866" checksum="075123B447F5A4AE" modified="2008-01-15" version="1">MSNDQYSNQPPVDPNYQPYNQTPPPNQQQPYSQTPPNQPQPYQPYSNQAPQSYQPQSQGQFVVPSANQLTSSFKSSSLGRRLAIGGGLLAWICYFLPWYHVSTEIFGVSDSTSFNGLRGLLPWMGFMVLTSVLVNLLGPFFGQQVYPRFQRSLNNFSLGKAAFFGLAAALGLALIGGFIVSPSDQGIAGIDAGFSFGFYLSILALGTATAGGWLMQQSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L7</accession>
    <name>A9B1L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1254"/>
    <dbReference type="EnsemblBacteria" id="ABX03902">
        <property type="protein sequence ID" value="ABX03902"/>
        <property type="gene ID" value="Haur_1254"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1254"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096711_0_0_0"/>
    <dbReference type="OMA" id="NDYLWHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1276-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27255" checksum="F1E18CFE50BB78B1" modified="2008-01-15" version="1">MSKIISIHSFRGGTGKSNTTANLASLIAATGRRVGVIDTDIMSPGIHVLFGMNEDDMKYSLNDYLWGKCEIKQAAYDVSSTVKGLTSGRIFLIPSSIKAGEIARVLREGYDVGLLNDGFHRLVEELNLDVLLIDTHPGLNEETLLSIAISDSLIIILRPDSQDYQGTGVTVDVAHKLDVPQLFLLVNKVPTSFNFAEVKARVEKTYNSEVAAVLPHSDEMMTLASAGIFVLQYPDHPLSQSLRGVANRLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Q2</accession>
    <name>NADA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Quinolinate synthase</fullName>
            <ecNumber evidence="1">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nadA</name>
        <name type="ordered locus">Haur_1289</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:25889"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the quinolinate synthase family. Type 3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B1Q2"/>
    <dbReference type="SMR" id="A9B1Q2"/>
    <dbReference type="STRING" id="316274.Haur_1289"/>
    <dbReference type="EnsemblBacteria" id="ABX03937">
        <property type="protein sequence ID" value="ABX03937"/>
        <property type="gene ID" value="Haur_1289"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1289"/>
    <dbReference type="eggNOG" id="COG0379">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047382_2_0_0"/>
    <dbReference type="OMA" id="CFCSTMN"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00569">
        <property type="entry name" value="NadA_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023515">
        <property type="entry name" value="Quinolinate_synth_A_type3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00550">
        <property type="entry name" value="nadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000212080" description="Quinolinate synthase">
        <location>
            <begin position="1"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="144"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00569"/>
        </source>
    </evidence>
    <sequence length="375" mass="41245" checksum="ED783F290F908A39" modified="2008-01-15" version="1">MTVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADLSGDSYGLSVDARKTAAEYIVFCGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQLEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGGACCTSSNAEPIVRWAKNLRPKMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQFRPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEINLVNRLQTNNPDKTIVSVSPFACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQKARLALERMLEIAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S8</accession>
    <name>A9B1S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2732"/>
    <dbReference type="EnsemblBacteria" id="ABX05370">
        <property type="protein sequence ID" value="ABX05370"/>
        <property type="gene ID" value="Haur_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2732"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_2_0"/>
    <dbReference type="OMA" id="TYMWGTR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2763-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="17667" checksum="4F30CD4A3C96CE7E" modified="2008-01-15" version="1">MTMDELDQAILEVLQTDARLPNRAIASKVGSSEPTVRRRIERLVDEGLIKIVAVASPYALGYQVVAIIGMQIDRAYQRQIEQALCNLPHVHFVGLTLGSYDVVLEAWLRSTDELLELLADHIAPLPGVQRVEPWQVLKLSKYNYDWGNQPSISNSHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1V3</accession>
    <name>A9B1V3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2757"/>
    <dbReference type="EnsemblBacteria" id="ABX05395">
        <property type="protein sequence ID" value="ABX05395"/>
        <property type="gene ID" value="Haur_2757"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2757"/>
    <dbReference type="HOGENOM" id="CLU_174646_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2788-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="101" mass="11759" checksum="738E01F5F7BFC9B0" modified="2008-01-15" version="1">MHYLACVVYCATLALGASVQYLHLRLGQWRWLHHALFFATWLSTATALTWRWWNGVEQWWLVSLIIPILALFPLQRASTRRHRWLGVSGLVVWAFILALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B219</accession>
    <name>A9B219_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative NAD(P)H nitroreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4738"/>
    <dbReference type="EnsemblBacteria" id="ABX07369">
        <property type="protein sequence ID" value="ABX07369"/>
        <property type="gene ID" value="Haur_4738"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4738"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_5_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4796-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02135">
        <property type="entry name" value="YdjA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026021">
        <property type="entry name" value="YdjA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000232">
        <property type="entry name" value="YdjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 3" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="19971" checksum="777F8C28F790C2AD" modified="2008-01-15" version="1">MATSNEVLAFLAQRRSYGLKEVSPEPIERSAIELILQAATLAPSHGVTEPWRFVVYSGEARAELGAALVAAAQGDPFQEAKQRDKVWMAPVWIALGMQPQPKNPEWEELAAVAMAVQNAHLMAAQLGLAAKWSSGPIGTHEIVAKTVGFEAPTKLLGFLYVGKPAVTPKPLARSDWQSKTTWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B259</accession>
    <name>A9B259_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4778"/>
    <dbReference type="EnsemblBacteria" id="ABX07409">
        <property type="protein sequence ID" value="ABX07409"/>
        <property type="gene ID" value="Haur_4778"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4778"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="NVLRKTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4836-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="22315" checksum="476D8EBCA44BA169" modified="2008-01-15" version="1">MIRVAIVEDQRIVREGLIAVLEDEATIEIVGEAANGQAALDLYAQELPDVVLMDLQMPVMDGPTAIGQLCQRWPQAKVLVLTTYATDEFIWAALRAGAKGYLLKDASADELVSAIQAVARGSTHLAPDIAAKLVAGVSNPQPESLTPRELEVLHLLGRGRSNGEIALELDIALRTVKVHVQNILGKLGATNRTEAVSIAVRQQLISLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B270</accession>
    <name>A9B270_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative homoserine kinase type II (Protein kinase fold)-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4789"/>
    <dbReference type="EnsemblBacteria" id="ABX07420">
        <property type="protein sequence ID" value="ABX07420"/>
        <property type="gene ID" value="Haur_4789"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4789"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145968_0_0_0"/>
    <dbReference type="OMA" id="DFEFACP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4847-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="26"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="27523" checksum="D802DB682AC448E5" modified="2008-01-15" version="1">MDILDTIIANAIQQFDLIAPVQVVTQFPSVNHQSIQLRAANGDFVIKVYTTDQDEATRRYEHMLVQWLSWRPASFTVPLPLRGRSIDYSHYDYNSDRFYSITPYIAGETPDFRMHADGQYHPSIQQWAYAMGTALGELQTILQARPAQQRRPMALFQSLLTYAQPRYDPLQLSAAQVGGSSDDEALWTWWRSEATRLMAFVANEYPDLPQQLCHNDFAPSNLLISDGRVAAILDFEFACPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B273</accession>
    <name>A9B273_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07423">
        <property type="protein sequence ID" value="ABX07423"/>
        <property type="gene ID" value="Haur_4792"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4792"/>
    <dbReference type="HOGENOM" id="CLU_841378_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4850-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="37743" checksum="1293CA7653BB2CAE" modified="2008-01-15" version="1">MLTLQDNYGDLLTKGAKLVRATTESSPDDEQYRRIIKAMVRIRVEGDVRAEVLAFKQSLEAHAESIQFQPITAVGERFVAYGAVLRRATPSNIEHFIDILRRFNEKVDTLLGLSFVQHIRRENEAKRWEGRTYHRRKRSKWKLSFIQSLVKRRNEAKIRASCAANDQYLSNAIALGPRSEATAAFVLTMRCFLDDTEECSLENLAHYYQDATIGTEHARFYLANRNVYNIALDGVTELIDREQVVDTDGNVIGSIETPLTQRQVFDLWVYGGLSHANLTKKQQFDALFGDPATRAMLRQSFVDWLDEYCGLLTAQSYVNKAMLLELEKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G2</accession>
    <name>A9B2G2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04007">
        <property type="protein sequence ID" value="ABX04007"/>
        <property type="gene ID" value="Haur_1362"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1362"/>
    <dbReference type="HOGENOM" id="CLU_2382181_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1383-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="94" mass="10557" checksum="5DD5780093ABC8AE" modified="2008-01-15" version="1">MDIQAGRIAIDNIHDAIANLEENLKLVSTPTPPLLEFNGDLLAFYIPANQAWCVQFNPKQGSKLNPVLHPFLPYYEAVTKFNYIAARVREESGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2I1</accession>
    <name>A9B2I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX04026">
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        <property type="gene ID" value="Haur_1381"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1381"/>
    <dbReference type="HOGENOM" id="CLU_1728849_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1402-MON"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="17299" checksum="34C6562EEBF6B196" modified="2008-01-15" version="1">MAATSETLDDCDSGQLPPAWVEAYAQQVRDCFSLQGWDIYVRPMTKEQHDEEPTTAGLAHVNHRYSNAVIEYWDQQPVEPLKRVLVHEFLHILVAPLTTLIEAMLLEIPVKRRGMFMHEMQIHAEEQVVTALTRIIFPLLQQSLAAHAIEE</sequence>
</entry>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05456">
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        <property type="gene ID" value="Haur_2818"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2818"/>
    <dbReference type="eggNOG" id="ENOG5034B33">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_1913617_0_0_0"/>
    <dbReference type="OMA" id="RWANLAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2849-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14871" checksum="6E0B26EEE8AC5F95" modified="2008-01-15" version="1">MIDRLFLSPTVHLNMGMLVVTVSILTMGYVCWLAWKGKQLNRWANLAIISMQLVIMLQALLGIKLLDQGLGVVQLYIHYVGGLAPLFFCSLFYWIPIARPQIKTRFAALVTVGSFLFVLMTFTIGQAYVSGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B304</accession>
    <name>A9B304_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Chloroflexia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07467.1"/>
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    <dbReference type="EnsemblBacteria" id="ABX07467">
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        <property type="gene ID" value="Haur_4837"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4837"/>
    <dbReference type="eggNOG" id="COG0491">
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    <dbReference type="OMA" id="GMQTAVN"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="31938" checksum="3276BF6EB40740B9" modified="2008-01-15" version="1">MTTELQQRTIQLGPTTITAIVDVTTPWPMLPVSDAIWNKVRAAYPSSFYNAETLLGRVHCYLIQQASRTILVDTGLGKAPPPTPALSSQQLEAQLSLMGIDATAIDTVFLTHLHVDHVGLNTHYVDDKLQARFPNARYLAHKAEQGLIEFMQTHTPERAGYLQDQVLWLNEQGYLDFFEADFELTEGITTWFTPGHSPGHTGLLIDHGTGERVLIAGDIFFNPIQMFHPSFATGLDVDKEQAHATRLAVLQQVSDGKTLVAACHFPTPSFGYVVPDGDAYRWQPIAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B357</accession>
    <name>A9B357_HERA2</name>
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        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
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    <organism evidence="6 7">
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    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="ABX07520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX07520">
        <property type="protein sequence ID" value="ABX07520"/>
        <property type="gene ID" value="Haur_4890"/>
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    <dbReference type="KEGG" id="hau:Haur_4890"/>
    <dbReference type="eggNOG" id="ENOG502ZSE3">
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    <dbReference type="HOGENOM" id="CLU_1459432_0_0_0"/>
    <dbReference type="OMA" id="YAKMPAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4950-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="20868" checksum="1392FC65FA1F86DE" modified="2008-01-15" version="1">MPFVDILLLLFVVLGLFYGFFQGMLKVGISILVFYLTIVLSSLYYRPLALAISKNSTTPFQVLEMLSFLTLLFVLFFALLWVASYTFRYLKVGGQLQYIDKVIGTFLGLILGAMIASIFAMMLRYLFSTTAPAVLDYPAMRFLQASTRASALKNVFLDIILPLIYGPIRPIMPESADALFRSIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F2</accession>
    <name>A9B3F2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1471"/>
    <dbReference type="EnsemblBacteria" id="ABX04115">
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        <property type="gene ID" value="Haur_1471"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1471"/>
    <dbReference type="HOGENOM" id="CLU_1719837_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1493-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735219" evidence="1">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="16620" checksum="9C37513C532E9B00" modified="2008-01-15" version="1">MRWRFGLLSCLSIILLSCASQTPDQPTPTAFGDLSAITAGTGYIQIFSGMPNPSWLLNANAVDAIQQVLQTATPATTRPEPPGLGYSGMYLELMSTGMPLRLTVFGEVIAVEQGASTHYLNDPNHVFERWLLEQARPQLQPAIYAMIKKNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T2</accession>
    <name>A9B3T2_HERA2</name>
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        <recommendedName>
            <fullName evidence="2">CpXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ordered locus">Haur_3432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3432"/>
    <dbReference type="EnsemblBacteria" id="ABX06068">
        <property type="protein sequence ID" value="ABX06068"/>
        <property type="gene ID" value="Haur_3432"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3432"/>
    <dbReference type="eggNOG" id="ENOG5032TQR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_628281_0_0_0"/>
    <dbReference type="OMA" id="QNPAMIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3469-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="InterPro" id="IPR025682">
        <property type="entry name" value="CpXC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14353">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpXC" evidence="2">
        <location>
            <begin position="28"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="461" mass="51084" checksum="EAFED5BE0491BAA4" modified="2008-01-15" version="1">MTNPPQGLEETTQGGPQRPVVPPQRVQIRCQNCQTPFVVALWTYVDVGVQPELKGAMLSGQLNVAVCPSCGAGGMLASPLIYHDPEKKFFWTLFPQELNLPTEEQERFVGEASKVAMQLLPPDAPRGYLLTPRRFITMQTMLETLLESEGITKEVMQAQRQRVELLSQLAEALEADRAENLLDSDQGKLAQVVAANKAALDGEFFLTLNSYIEAALQQGREDSAEMIGELSQRVMQLSGFDPVAAGLQEPAVEDVVAALRDADDASLEDVISNYRPLIDDETFDAWDAQIAALPEADQAEAQARRDHIYTTLERMDAEAQAIFEKANGLLRDALQAEDPRALLVERHKELSEAFFVVIDANLNAAMRTNQQIIAEQLMLLRQTAAEVLQEAMTPQERLINQLLSAETAGDATKLLRKNMALVNGDFVKEVNELAEQMEKAGRKEVVERLRQVARESASLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X7</accession>
    <name>A9B3X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3477"/>
    <dbReference type="EnsemblBacteria" id="ABX06113">
        <property type="protein sequence ID" value="ABX06113"/>
        <property type="gene ID" value="Haur_3477"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3477"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_2_0_0"/>
    <dbReference type="OMA" id="ICAGPGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3514-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="809"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="877" mass="96372" checksum="F42440B33CF778AE" modified="2008-01-15" version="1">MSDLHQLVLLTKLAAPQIPSTLVERQHVLERLTCRGRVSLITASAGSGKTTLLSSLANARQRVAWLTLDSNDNDAIRFARYLIVALQTLEPTLGRNAMALLNGLQQPAIEAVLTLLINEISVAQPAPMLLVLDDYHWIDAQVVHRALAWLIDQLPAQLHLIIASRNVPPLPLGRWRGKGYLTELDASVLQFNSAETAQLLAQTLGDLPDQSTIDWLTERTEGWVAGIQLAALSAKDRANVQQILSGFSGSHRYIFDYLAEEVLDQLDPATLEFLLATSVAERLTGALCDQLLDWQPGTGAQMLAQLADAQLFLVALDDERRWYRYHHLFAEFLRFRLQQLDPQAPAEFLQRASAWHAANNDLNSAINYSLAANDHQQAANLIAQFGRDALMRGEALSVRSWLARLPAIQLSQSSHLALIAAWSQLLTVDILGIEEHLQQARAHLEALPQAEQARANAEIATIEAVLLRFGDNIEHSMQHSQAALELVEHDDLVLRGILLGNLTVSARLTGNLTIAVAAASDAVAINQRSGNTFAMLLAIADLGQIQAQQGHLRKAAATYRRGIELASERGWHQVPALGLIHVGLGEVCYEWNQLEEAQIHAEQAIAIAQINGYLDIATDGYRLRARVEHANNERRSSQASTEQALHFAQRNNVGRFINEVQASQARMALILGDVATVRRWAQTVQKTTWQWQQVSAANTYARWLIANNEPAQALQLAQPLLEQTLKFGGNRLEWLLTLALAYAAQHNLKPAQTQLEQALAISEQEGALRTFIDAGAGLAQLLREGTSYAAQRAAIVAAMLQQSSTSSAAQSLNEPLSEREIEVLKLLALGHSNAEIAERLVIAIGTVKRHVNNLLGKLNARSRTEAVAIARDEGLLH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-10-14" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B458</accession>
    <name>RS2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsB</name>
        <name type="ordered locus">Haur_4961</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B458"/>
    <dbReference type="SMR" id="A9B458"/>
    <dbReference type="STRING" id="316274.Haur_4961"/>
    <dbReference type="EnsemblBacteria" id="ABX07591">
        <property type="protein sequence ID" value="ABX07591"/>
        <property type="gene ID" value="Haur_4961"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4961"/>
    <dbReference type="eggNOG" id="COG0052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040318_1_2_0"/>
    <dbReference type="OMA" id="SYIDRAY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000351996" description="30S ribosomal protein S2">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <sequence length="255" mass="28719" checksum="A9FCF0C61D9B6126" modified="2008-01-15" version="1">MTDTTTNRVVSLKALLEAGVHFGHQTKRWNPKMRPFIFTDRNGIHIIDLQQTVTSLQSAYRFVADAVAGGGKVLFVGTKKQAQEAVRDEATRSNQLYVTQRWMGGLLTNFSTIKRRLQFLHDLEARRDRGEFNLVTKAEALKLEDEIVKLNRVFGGIKTMERLPAAMFVIDPHKETLAISEAKKLGIPVVAMVDTNCDPDPIDYPIPSNDDAIRAIRLMAGKIADAALEGQNRRQSQHIEERALAEQTKYEEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A1</accession>
    <name>A9B4A1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02658">
        <property type="protein sequence ID" value="ABX02658"/>
        <property type="gene ID" value="Haur_0006"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0006"/>
    <dbReference type="eggNOG" id="ENOG502ZFZK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1208439_0_0_0"/>
    <dbReference type="OMA" id="HETIQIQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-6-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="229" mass="25052" checksum="9BBF74F27BE8FC19" modified="2008-01-15" version="1">MGLVFNVLLLGIPLGLTVLGASRGIQREAMTLIGILLGALLAELWGPIWGPNNATRFNQDIANTTAWISIILLLVCTIFIGYGGALLLPSRKQLAQGRSRWFGAGAGLFNGVLLLSLILRYGNVYNNDLRISDWVASSRVAMLFIERFPTMLLIGIVTIALLVNLRLLQRLIYKIHGKDTKPEEKKKAEEKPAAPPPPPEPKPPAPDTVNNPILRDLILAEIKKDKPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N5</accession>
    <name>A9B4N5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1557</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1557"/>
    <dbReference type="EnsemblBacteria" id="ABX04200">
        <property type="protein sequence ID" value="ABX04200"/>
        <property type="gene ID" value="Haur_1557"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1557"/>
    <dbReference type="eggNOG" id="COG0382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060108_0_0_0"/>
    <dbReference type="OMA" id="LPTVWTN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1581-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="30899" checksum="B3C660C94DC0AB32" modified="2008-01-15" version="1">MNSNAKSDWLAYLELMRISNNPTVISNTLAGVALAGVSLGDWRVWLLALAFSLFYSAGMVFNDWCDYAIDQRERPERPLPSGRVSRNAALVLTIGLFGIGLACVALVSWQGLLWAGGLVGLIVVYDLWHKTNPISPVLMASTRILVYLSTIAALGAAFSWQVWLAVGLLFSYVMGFTFIAKSELRPQLKALWPAICVLLPIGYALITPDFSPILVSVALLSWSLHSIRLVYRQRQIGPAIGRLIAGISLFDALVCIVAGNLWACAFAIAAFGLTRLAQRSIQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N7</accession>
    <name>A9B4N7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1559"/>
    <dbReference type="EnsemblBacteria" id="ABX04202">
        <property type="protein sequence ID" value="ABX04202"/>
        <property type="gene ID" value="Haur_1559"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1559"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_0_0"/>
    <dbReference type="OMA" id="FVDYYAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1583-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="33"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="38897" checksum="6883428ED11C286A" modified="2008-01-15" version="1">MDTIQVRPDEQLNESALADYLYDKLPGASQPLTVRQFGGGAANLTYLLDYGHYEYVLRRPPLGPVAPSAHDMGREYRVLSQLHPAFAQAPQTFLFCNEPEIIGAPFFIMERRHGTVVRRELPHQFNTPEAPRALSLALVDTLADLHAVDYSMIGLSHIGKPDGFILRQVVGWYERWNKAKTDDLPAMENVYAWLCEQQPPASAPTLVHNDYKLDNVMFRQNDPSQLIAVFDWDMCTLGEPLADLGTLLCYWSQPDDPPALQAVAMMPTDGRFATRDELVARYAERSGRDVSHIRYYHVLGLYRLVVILAQIYARYQRGQTKDARFAQFGEIIPIMAQAAADLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N8</accession>
    <name>A9B4N8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1560"/>
    <dbReference type="EnsemblBacteria" id="ABX04203">
        <property type="protein sequence ID" value="ABX04203"/>
        <property type="gene ID" value="Haur_1560"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1560"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_1_2_0"/>
    <dbReference type="OMA" id="DTVGNRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1584-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="135"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="244"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="405" mass="45095" checksum="42A40C1F963A77AC" modified="2008-01-15" version="1">MDFAIPSHIAAMREQISQFLREKVYPNEQAWFDYDEKAYPACSEDHPEIKQLQAEVKELGLWAGHLPREAGGMGLSIMEYGLLNEIIGRSYFAPRIFGSNAPDSGNAEILWHYGTAAQHEHFFWPLQQGAVRSFFSMTEPDVSGADPTLLQTTAELVDDQWVINGRKWYSTNANGAGFGIVMAMTDPDAPTHLRYSQIIVPAETPGLTLVRPISVMGHTTGGGHWEIEYTDVHVPAENLLGKRGQGFAIAQTRLGPGRIHHCMRWLGQAQRAFDLMCEYSTKRVAFGGPLADKQVVQHWIAESAAEIQAARLSVLHAAWQIDQAGAKSARIDISLIKFSVAAMLMNVLDRAIQVHGGLGVSDDTPLAFMWRQGRASRIYDGPDEVHKMVVAREILKRYGYPERKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B510</accession>
    <name>A9B510_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.227</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3511</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.227" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3511"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06147">
        <property type="protein sequence ID" value="ABX06147"/>
        <property type="gene ID" value="Haur_3511"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3511"/>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037404_0_2_0"/>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3548-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="3">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="4">
        <location>
            <begin position="148"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="35742" checksum="FC47BC30EF3C754D" modified="2008-01-15" version="1">MEGDLVQRESTIPFVGLPAAAMRGRNPLQMVKNAGVLIKGVLAARSLLRRERPAAILGTGGYVCVPLFVAAALERVPTLLYLPDIVPGWAGRVLARLATRIAVTFDDSKRYLPAHKVVETGYPVRGELFNQNKALCRAIFGLNDRLPVLLVYGGSRGARSINQAVAALLSDLLELAQVVHVCGRNGDEAWLREAQAKLSPELASRYHLYPYLHADAERSMSTAFGAADFALSRAGASTMAELPAAGIGSILVPLTMVKQEYNAAALADRGAAISIPDEAMLGSGEPTQGRLWRELSAVLSNPLRLQTMAQRSASLAQPDAGARLASEWLALARGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B519</accession>
    <name>MRAZ_HERA2</name>
    <protein>
        <recommendedName>
            <fullName>Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mraZ</name>
        <name type="ordered locus">Haur_3520</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B519"/>
    <dbReference type="SMR" id="A9B519"/>
    <dbReference type="STRING" id="316274.Haur_3520"/>
    <dbReference type="EnsemblBacteria" id="ABX06156">
        <property type="protein sequence ID" value="ABX06156"/>
        <property type="gene ID" value="Haur_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3520"/>
    <dbReference type="eggNOG" id="COG2001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107907_0_5_0"/>
    <dbReference type="OMA" id="RGQERCL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000134803" description="Transcriptional regulator MraZ">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB 1" evidence="2">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB 2" evidence="2">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <sequence length="143" mass="15897" checksum="B819F2996D2A6E2F" modified="2008-01-15" version="1">MFLGEYEHTVDEKGRLAIPAKFRAGLAEGLVLTRGFDQNLLLYPMPVWRELAARINALPITQPSARNLRRLMFAGASDLGLDKQGRIVLPPNLRQYATITNQAVVTGMDSFIEIWSAERWQTVLDSFADEAPALAEHVSAFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H3</accession>
    <name>A9B5H3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ordered locus">Haur_0146</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0146"/>
    <dbReference type="EnsemblBacteria" id="ABX02798">
        <property type="protein sequence ID" value="ABX02798"/>
        <property type="gene ID" value="Haur_0146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0146"/>
    <dbReference type="eggNOG" id="COG0148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_2_1_0"/>
    <dbReference type="OMA" id="EFMIIPV"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="364"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX02798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="428" mass="46132" checksum="F7DAA8C32986F00B" modified="2008-01-15" version="1">MALITHVRGREVLDSRGNPTVEVEIGLEDGTLARAIVPSGASTGAHEAVELRDGDKSRYGGKGVLKAVKHVNEDIAEAIEGLEALDQITLDKTLIELDGTKNKGKLGANAILGVSLATAKAGALSVGLPLYRYLGGVFGHTLPVPMMNILNGGKHAQDSTDFQEFMVMPVGAPSFREALRWGAEIYHTLKNVLHDRGLATNTGDEGGFAPSLPSNEAALEVIVEAIQKAGYTPGKDVMLALDPACSEIYENGIYNLAREGRKLSSEEMVGYWENLVNKYPIISIEDGLHEDDWGAWSSLRQRIGDRVQLVGDDLLVTNVERLNRAIKENSANSILIKLNQIGTLTETLDAIQMAQRAGWTAIVSHRSGESEDVTVADLVVATNAGQIKTGAPARTDRVAKYNQLLRIEEELDSQAKFAGWSAFAVKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V6</accession>
    <name>A9B5V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carboxyl-terminal protease</fullName>
            <ecNumber evidence="6">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3111"/>
    <dbReference type="EnsemblBacteria" id="ABX05749">
        <property type="protein sequence ID" value="ABX05749"/>
        <property type="gene ID" value="Haur_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3111"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017295_3_2_0"/>
    <dbReference type="OMA" id="TFNQVDW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3143-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="472" mass="51517" checksum="56A82DEF98E016F2" modified="2008-01-15" version="1">MSEFQPTSGGSSTSSAKLWVVLSGIVGVLLVVAIALGAGYYWGSSSKEQTMTAANQALATETAQIMQATQQALPPANADENFQTFWEVWNLVNKEFYHTEPIDEKQMMYGAIRGMLQSLGDDFTGFQEPEAAERSREDMRGNFEGIGAYVEYKDGQILIVSPIEGSPAEKANVRAGDIVVAVDGKQISEVIENLERDQALAEAIKLIRGPKGSQVVITVYRTSEEKQIDITIIRDTIPLISVRSSMIGDIGYIQLSEFKQTSYDELDQAIAKLKTNNPKAIIFDLRNNPGGYVNQAQNVLGRFTKDGVTHYQENSDGTQKEYRTLQQGDAQELFDLPVVVLVNGGSASASEIVSGAMQDTKRATLIGEKTFGKGSVQSVHTLSDKSEARITIAHWLTPNKRAIHTLGITPDYVVPFSDDATQYPIECILNRTPADGATSCADSQLFWALKFLNEQQTPPPPPTPTITPTPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W0</accession>
    <name>A9B5W0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05753">
        <property type="protein sequence ID" value="ABX05753"/>
        <property type="gene ID" value="Haur_3115"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3115"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021290_2_0_0"/>
    <dbReference type="OMA" id="YRQTMFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3147-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="119"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="208"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="603" mass="68084" checksum="A7336B1F60F624F4" modified="2008-01-15" version="1">MTMVEEQVPTREEVSAEDTWDISSLYADQAAWEADVERISSDLLPALTNLQGTLANGPEALLAVFQAQEALGMVLEQIYVYASLRADEDTANQHYQALEERATALSIKASAATSWIEPELLALSDEQILGYVSSLPALELYRRALEEQIRLRQHTRSGEVEELLAQTGEISRGAQTTFNMFSDADLKFPPIEDEQGKPLEVTMGRYAVLLENPNQRIRRDTFMSIHRTYRQFRNMLAANYATNVRSNIFYAKARGYDSALDASLKPKEIPMSVYDNLISTVHEHLPKLHRYGAVRKRILGVDSLHAYDWFVPLNGAAPTKIDFEQGASLILSALEPLGAEYSSNLGHGLESRWVDRYENKNKRSGAYSWGCYTSQPFILMNYKNNLNSLFTLAHELGHSMHSLMTRKYQPYTYGHYTLFVAEVASTLNEALLAEYMLKTSDDPALRLQLVTQQIDDIRGTLLRQTLFAEFERETHRMVEQGEALTADNLSALYRRLIEQYYGPELVIDEELDIEWARIPHFYRSFYVYQYSTGISAALALADKILTEGAGAAENYVNFLRGGNSKSSIDLLKGAGVDMTTPDPIHRAMNRFGDLVTKLDELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z0</accession>
    <name>A9B5Z0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3146</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3146"/>
    <dbReference type="EnsemblBacteria" id="ABX05783">
        <property type="protein sequence ID" value="ABX05783"/>
        <property type="gene ID" value="Haur_3146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3146"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="HFMEEAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3178-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="319" mass="35595" checksum="40072B0ED92B6769" modified="2008-01-15" version="1">MELIVETHNLTQRFGTHLALNQVNLSIPKGAVYGFIGPNGAGKTTTMRILTTLLQPTAGEAFVNGISVRQDPDAVRKMIGFMPDYFGVYESMRVWEYLDFFAHIYGIKQPRRTSLIQELLQLVDLTEKHDSYVMNLSRGMKQRLSLARTMAHDPSLLILDEPASGLDPRARIELRELLRELSRMGKTIMVSSHILSELAEMCSHIGIIERGTLLASGPVEQIMQDLRPHKLIEVQVLERAMPALQMLKQLPTINDVHLANELADDQAGGKLAINFSGTAEESSAILSNLISQGFRVNHFAERQSDLEEVFLHVTQGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z1</accession>
    <name>A9B5Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3147"/>
    <dbReference type="EnsemblBacteria" id="ABX05784">
        <property type="protein sequence ID" value="ABX05784"/>
        <property type="gene ID" value="Haur_3147"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3147"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066398_0_0_0"/>
    <dbReference type="OMA" id="CSTYFKR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3179-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="31454" checksum="461DE69ECCA0C110" modified="2008-01-15" version="1">MKAILQKEFRSYLRGNRAFTTLSIYLFILSGLCVLIYAGQSESGFVDRSEIGLSLYSTAAAVALFQLTFFAPSLNASSLGSERDRQTIDVLMVTPVRRYQIILGKLIAPCLFLFLLSLASLPIGALALLIGGIEARDLWIALAIQLVTVLGYGSIGIWGASWAKTSRGAMMATLGLALVLAIGLPLLAILVLAVLSNDQPLFDSIMNNGFIRNLGVVALSFSPFFSLIMWIQSVTDGQATTWTLDLQGQLGGGTILQPWVISVLLWLVLIPFLIWRSSKQLQKSVAHSSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B686</accession>
    <name>A9B686_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3661"/>
    <dbReference type="EnsemblBacteria" id="ABX06297">
        <property type="protein sequence ID" value="ABX06297"/>
        <property type="gene ID" value="Haur_3661"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3661"/>
    <dbReference type="eggNOG" id="COG4214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_0_0"/>
    <dbReference type="OMA" id="FDVWNKR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3700-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="405" mass="42625" checksum="B11DF3C79E762077" modified="2008-01-15" version="1">MSAELKTNESSKAAGFNFATVVDFFKNNMREYGMLVALVIIVLYFQFQTDGVLLQPLNVTNVILQNSYIVVMALGMLLIIVAGHIDLSVGSVAAFVGAVAGYMLVEKDYPIIVAFAACIAIGAAIGAFQGYWVAFRKIPAFIVTLAGMLIFRGLTLVMLGGTSLGPFPSSFREMSTGFIGDPIGGAESALHITTLIVGLAFAAIIVYLDLVGRKNSRSFNFPVMSTPLFIAKNALIVGIILAFCYILASYEGLPNVLLVLIGLIALYMFVTKKTVIGRRIYALGGNEKAAKLSGVPTDRLTFYTFINMGVLAAIGGLIFTARLNSATPKAGTGFELDVIASVFIGGASASGGIGTVFGVVIGALVMGVLNNGMSIAGVSVDWQQVIKGAVLLVAVYFDVSSKNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G5</accession>
    <name>A9B6G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0216"/>
    <dbReference type="EnsemblBacteria" id="ABX02868">
        <property type="protein sequence ID" value="ABX02868"/>
        <property type="gene ID" value="Haur_0216"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0216"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1784220_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="15319" checksum="1DD72875441118CB" modified="2008-01-15" version="1">MPAPIIQVEYNHLLQVAQRFRTKAEAVVSLRQQLRATVGQLRNDWSGIAATAFFHEFQAEVDPALERLREALETARDVAMAIHTGMRSAEEAAAALFKGNFGDIATEAVAAGLGAALGTTIGLRTAPPAPRLGSANLPGGPSSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6I7</accession>
    <name>A9B6I7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0238</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the gmhB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0238"/>
    <dbReference type="EnsemblBacteria" id="ABX02890">
        <property type="protein sequence ID" value="ABX02890"/>
        <property type="gene ID" value="Haur_0238"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0238"/>
    <dbReference type="eggNOG" id="COG0241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085077_2_1_0"/>
    <dbReference type="OMA" id="EHQICLE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-241-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="179" mass="19899" checksum="BC8C0A2E78E3B361" modified="2008-01-15" version="1">MSQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGYYRAEDMHLVHQRISELLQPFNAHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAIDLSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLPEHAMLVANLNAAVDLIVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Z3</accession>
    <name>A9B6Z3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3'-5' exonuclease DinG</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dinG</name>
        <name evidence="6" type="ordered locus">Haur_3224</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">3'-5' exonuclease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3224"/>
    <dbReference type="EnsemblBacteria" id="ABX05861">
        <property type="protein sequence ID" value="ABX05861"/>
        <property type="gene ID" value="Haur_3224"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3224"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012117_1_0_0"/>
    <dbReference type="OMA" id="VVTNHAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02206">
        <property type="entry name" value="DinG_exonucl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006310">
        <property type="entry name" value="DinG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01407">
        <property type="entry name" value="dinG_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="241"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAH box" evidence="4">
        <location>
            <begin position="460"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="276"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="927" mass="103846" checksum="7BD63CFF111B3A8B" modified="2008-01-15" version="1">MEPIYIALDLETTGLEPGRDEIIEVGAVKFRGNEVLETYQTLVKPKQVLPIKIARLTGIDAHELTTAPTFNSIGGQLAKFLKSYPIIGHSVDNDLRFLQQQGLKVTQPHYDTFDLATLLIPQLPNYSLSTIAEHLQIQHPDAHRALADAEASRLVFSALLDKLAELSAAELHSIAQTTQKLQWPLAKLFGEIAKRRVQTLWQAPIEFQPKPLVRPVALEPTGNQQELDAQAIGAMFGADGGFSRMFPGYEPRQPQIEMTEAIAEALNQGDTLMIEAPTGTGKSLAYLVPAAQWARQRGERVVISTNTINLQDQLCSKDIPTVQALLAEQPDQWPALRAVQLKGRSNYLCLKRYESFRAHPDHNEDQTRGLLKLQLWLPSTNSGDRAELMLIQGEQQVWNNVNVDPDQCLRQRCSLYNECFFFKARAEAENAHIVVANHALLMSDVKSPGILPRYDHLIIDEAHNLEDVATDQLGFTISQHSLTGLLNDMHSAGGVRLAGGVLNEWSQIFRLSTVDHKEQRKLEDLSADLRPNVDKAREAAQQLFSIFNDIMAKDRSVTQYDPQLRITSKVRRHTEWTQVEQTWENLSINLRKLGDGFGKLQAILDNLEGRDINGYDDLVMRVKGMVNACTELQRQFDVVIYGNEETVAWLTADQRRRELLVQAAPIHVGPLLTEDLWLKKRASILVSATLSVSNSFDYPKQRLGLDEATTMQLDSPFDYSKSTLIYLPTDMPEPNERNYQRAMEDALINLCKATGGRTLALFTANASLKQTYHGISESLEQADISTLAQGMDGSRRSLIQRFKSDPRTVLLGTASFWEGVDVVGDALSVLVITKLPFSVPNDPVFSARSEGFDDAFAEYSVPQAILRFKQGFGRLIRSKDDRGIVVVLDRRLLSKNYGRQFLESLPDCTIQRKPLAELATTAARWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B720</accession>
    <name>A9B720_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3251"/>
    <dbReference type="EnsemblBacteria" id="ABX05888">
        <property type="protein sequence ID" value="ABX05888"/>
        <property type="gene ID" value="Haur_3251"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3251"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_599606_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3286-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="456" mass="45629" checksum="AF7590F4F5738F7B" modified="2008-01-15" version="1">MTADIVQHKSDDMEQVSSRFQKLHDHQVQMEAMIRRMYEELRGGAWQGDAAQAFFAEMNEHIFPAMKRFQNVLAVSGEVTKQISQIFRQAEEEAAKGITFDGSGAPSGGGNGTASAGGGGGGNADGSGSGGSNAGATGGGAGIAAGGGGSSSGGGGGGSSSGGGGGGSSSGGGGGGSSSGGGGGGGSSTAGAGGGGGGGGGGGSSQEPMSTEQVFNDKYMGDLVGQQFQGAGNPELNSAMELLTSGNATPEQIEEALKKIAAARGVPLEKIQADYGKFLELREQAAKTGAANGQSAVEAINQTFHGDFMGSTSSLRYGKVVGDVLGIDPVFGSMLNPSGGLVGPGNKAIDLGDSPVSYHGAVHDAAGYLFNYHDMGPGYNYLGLERRDTANPLTGQESGIRYWNEKMGNTGIGATISNGAGSLIGKAQDAVNWFGDVKQDVQNTWSGVKDWFSKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C0</accession>
    <name>A9B7C0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3767"/>
    <dbReference type="EnsemblBacteria" id="ABX06403">
        <property type="protein sequence ID" value="ABX06403"/>
        <property type="gene ID" value="Haur_3767"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3767"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086384_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3809-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="26"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="32582" checksum="130FA72C0CC47FEB" modified="2008-01-15" version="1">MHALDQLHRLTERIFWMPADSRTDRPMLGLVVGDHECLVIDAGNSPAHVDLLRNAIEAQALAQPTCLALTHWHWDHVFGAATLNLPSYASQETNRILQVLATLDWSDAALDQRVADGLEIGFCRDMIKAELADRSQLQIVPATTSIEQQFMLDLGNCVAELIVVGGDHAHDSTIVYVPSQAVVFLGDCIYDDLYHGARRLTTSQIFPLLERLLALPADFYCASHHEQPLTRAEFEAEAQLLRHIGTIVNQIGADPDTILAQISQQLAIPLTEDHHDIMQAFLAGLALPEVQSMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L7</accession>
    <name>A9B7L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0338"/>
    <dbReference type="EnsemblBacteria" id="ABX02990">
        <property type="protein sequence ID" value="ABX02990"/>
        <property type="gene ID" value="Haur_0338"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0338"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_0"/>
    <dbReference type="OMA" id="LNHHDLW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-341-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="37385" checksum="F44F2C4F80C3867B" modified="2008-01-15" version="1">MMKAGFFRHHGGLEVLEYGDLAEPVAGPDEVLVRVRAAALNHLDLFVREGLPGLNLPMPHIGGCDIAGEIAAIGEGVTGWREGQRVVVNPNIWCGACEYCIAGEETLCDRYGVIGEHQTGGLAQYIAVPARNLYAIPADYAFEQAAAVPLVWMTAWRALIGQAQLRAGQSVLILGAGGGVASAAIQIARYAGATVYAASRSPEKLARAQELGADYVVRSDGDWGRELWKQTNKRGVDVVLENVGAATWESSLRSVAKGGTVVTYGATTGPIVNIDIRKLFWRQFNLIGSTMANNREFNTIMRLVFWERRFQPLIDKVFPLSEIQAAQRYLESAEQFGKVVITIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7W3</accession>
    <name>A9B7W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">YidE/YbjL duplication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1848</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1848"/>
    <dbReference type="EnsemblBacteria" id="ABX04491">
        <property type="protein sequence ID" value="ABX04491"/>
        <property type="gene ID" value="Haur_1848"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1848"/>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035023_3_0_0"/>
    <dbReference type="OMA" id="AMWLIRL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1877-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="274"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="545" mass="59212" checksum="1151C1794F76D961" modified="2008-01-15" version="1">MLDLLASNPLLLLFVVAAIGYPLGQLNLGGVRLGVAAVLFVGLAIGSLDERLKLPEVLYQFGLVMFVYTVGLSSGHQFFRSWKSKGLRDNLFIGGMIVVAYLFAILAHSFFSIKPTLTVGLFTGTITNTPALAAAIEYLKSVLPEQELAAVVNDPVVGYSIAYPMGVVAMMLAIVFVQRLWRIDYVKELASRHDLAGNHHDITSRTVEITNPEVTNLSVQALIAKYHWPMVFGRYRRDGHVAVTTGATQFMLGDHVSIVGASEVLEKALAVLGKETDDISNDRRDLDYRRMFVSNPKIVGIRLEQLNLPQVLGATITRVRRGDVEMLPTADTRLELGDRVRVIARRADIPQVSRFFGDSYRALSEVDILTFTLGLVLGLVVGSLVLPLPGGVSIKLGFAGGPLVVSLILGALDRTGPLVWNMPYSTNLTLRQIGIVMFLAGVGTRAGYDFVKFLFSSNGLLLFGVGAAITFSLAMLILTIGYKVLKIPMGILTGMLAGFQTQPALLSFALQQSNNELPNQGYAAVYPLALIIKIILAQLLLIQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y4</accession>
    <name>A9B7Y4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3280"/>
    <dbReference type="EnsemblBacteria" id="ABX05917">
        <property type="protein sequence ID" value="ABX05917"/>
        <property type="gene ID" value="Haur_3280"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3280"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_2_0_0"/>
    <dbReference type="OMA" id="IHFYEAK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3317-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010211">
        <property type="entry name" value="Redox-sen_tscrpt-act_SoxR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30204:SF0">
        <property type="entry name" value="PTHR30204:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15689" checksum="2C745E8535D097A7" modified="2008-01-15" version="1">MPGLSIGEVAQQTGLQSSAIRYYEQMGLIPKPQRHNTRRRYDSSVLQWIDLINLARKAGFSIAEVQTLIHGFSEDTPPSARWRTMATTKLTQVAQQIQDLQQMQELLNHGLQCQCLRLEDCRISNQQGCSEQCNGADQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z9</accession>
    <name>A9B7Z9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3295"/>
    <dbReference type="EnsemblBacteria" id="ABX05932">
        <property type="protein sequence ID" value="ABX05932"/>
        <property type="gene ID" value="Haur_3295"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3295"/>
    <dbReference type="HOGENOM" id="CLU_2464814_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3332-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="88" mass="9343" checksum="73D26CD94650969D" modified="2008-01-15" version="1">MPSQPVSGNAQTVISLHQAQFATPAEQINVLIDEALTWPASNLGCSDNGGIGRAVLTPGFRVVLEVAGVRYAYHAGRDAQFFLCNTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H4</accession>
    <name>A9B8H4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07638">
        <property type="protein sequence ID" value="ABX07638"/>
        <property type="gene ID" value="Haur_5008"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5008"/>
    <dbReference type="HOGENOM" id="CLU_1882896_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5071-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14729" checksum="77C3442F9EE69604" modified="2008-01-15" version="1">MAVRVKGIRCTEDDLERNRLLRVHRDDDESESELMLKAMRLGIRILSAEAWAAGEGQYGGYDPQVLAQRLQADLLPVLEFLMRRDALPALLQSQGMHSTGVVPTTVAPTPPPAGIQREASGAVLAFSGGFLDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K4</accession>
    <name>A9B8K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07668">
        <property type="protein sequence ID" value="ABX07668"/>
        <property type="gene ID" value="Haur_5038"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5038"/>
    <dbReference type="HOGENOM" id="CLU_2382182_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5101-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="94" mass="10260" checksum="B3287C9CB9D0CCB2" modified="2008-01-15" version="1">MADLAPTVGIAAACRALGVPRSAVYRAAQPAPASALRHRSTRALTPNEGVHIRTVINNDRFADCTPRQIYATLLDEGIYLCHRTLQLRKIHMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N6</accession>
    <name>A9B8N6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_5072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07700">
        <property type="protein sequence ID" value="ABX07700"/>
        <property type="gene ID" value="Haur_5072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5072"/>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5134-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="23647" checksum="A2773D23D37B04BE" modified="2008-01-15" version="1">MNSLINVIIGDDHPVIIDGLQMYLKACPSIKVIATARSFDAVKNVLVQSPTTPLVLVLDISGMGSPALSFVQGIIRQYPYCRIIIFSSNLKLAPDFFAIGVTGYVIKEEMLEYMRLAIETVHRGSTYYSPMVQEFLDTTSMVRQEFQLAPREIHILEHLSQGLGTIDIANELNIDGRTVQNYITNLRKKLNCLERSQLVIWYRTMYGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X7</accession>
    <name>A9B8X7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction protein with Nacht domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07791">
        <property type="protein sequence ID" value="ABX07791"/>
        <property type="gene ID" value="Haur_5163"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5163"/>
    <dbReference type="HOGENOM" id="CLU_004327_1_0_0"/>
    <dbReference type="OMA" id="PVEANEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5225-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="148"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="969" mass="110625" checksum="E2DC80E5B20896E8" modified="2008-01-15" version="1">MPDTTIGSVNTNYSMIDGPVVGINLGTIIYGRAPEEGERQSLVRYLEQLSNSHRKIRVIGLGPSRLESGIDLASVYIMLAVQKRYRIVRKLTSFEIIDYQRQKLRIPHELKPDRCLPDQAIIKIGKHQRYGWLMFRAELATETIAQYQYLILCGAPGSGKSTFAKHLVWALAQRGLDQINHQTHLRGWTDKRQLLPIFMPLRQLAGALAGNDLGLHAEPKIGLLLDALCDYLQTHYGLDEPRTLLTAGLNQRHKVLFVFDGLDEVPVEANEHSLDRASLLRFLRIFADHQPNARMLITCRSRAWTSEYRMITQWPMHELAHLTGGQITHFVHYWFPQLVLSGVIGHDEAQRYSTELLKALQHPKRQKLRLMAENPLLLSMMIFVLAENGVLPRDRHSLYEQVLGQLLGQWDAKREGDNLGQAIGDERITSQELRNRVLDRLCYHAHMQALSVDGRGRIHGRELRLELMDYFNRVKVADPYRAAERCIAYIDQRSGLLHPEDAGMVYAFAHLTLQEHSAGRHLLFYESIGQILALRHDDRWREPIFLGVGCLTSESLGSSKISELLTALIDRYDYGSDTCKPSHVWYRDVVLAAELGFDRDWGLLSGTGIDVRRIKREIRLGVVQMLHDRQHAQSALEYFYGAAMKPTPLLVKERQHAAELLAGLGDPRYPIDGTQWQQETTHLSQQFGREGTHYWRYMPAGQYQRGDAGTDIAETIEKHLGDFDPAGMNHRGQGDTQIGDVGVVPHPYWIGQFMVTVEQYQAFIQAGGYHTDRWWSTHGKAWKTMIACSEPWWWEQQTLQQYINQPIYGVSWYEAVAYCNWLNHYLQPMLPVGYRVCVPSETEWMSAAYNDEHGQFHNYSWGNQPLTPEHAVYDWVEERRPAPVGLSRMGDAPCGAADMTGNLWEWTATLDGKQDEHIDESAVNDACLITLRGGSCYDNVTTILFAANDTSLPINVSYNRGFRCVIARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B912</accession>
    <name>A9B912_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_5199</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07826">
        <property type="protein sequence ID" value="ABX07826"/>
        <property type="gene ID" value="Haur_5199"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5199"/>
    <dbReference type="HOGENOM" id="CLU_000445_90_1_0"/>
    <dbReference type="OMA" id="PHVLTHM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5261-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="24600" checksum="BF4E76D805166F3E" modified="2008-01-15" version="1">MRIVLADDHTMVRQGFRAILEHHLVCTIIGEATTGTEAMTSITHLQPDVALVDLMLPEATGIAVTRHVKATTPHVAILIVSMYGDLGYVDAAMQAGASGYVLKEADAMELVTAVQAVAAGRRILSSHLEGYWHMPSFRPNNTIPIDPYDLLTSRERDVFAGAMQGNTSVQIAAHLCLSVRTVEAYRASMLRKLGLRTQTDLICFAVRTGRMPVVTNPPIHDERIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B915</accession>
    <name>A9B915_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07829">
        <property type="protein sequence ID" value="ABX07829"/>
        <property type="gene ID" value="Haur_5202"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5202"/>
    <dbReference type="HOGENOM" id="CLU_1439273_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5264-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20851" checksum="5630104210AAE130" modified="2008-01-15" version="1">MYTIFTPTIGRYRKTAIYATCVSPLPTVADEPDRTTQTVVAFTVRPLPPYPDIYWNTAGVLLVHERLAAIFDAFDTPHTSRPVVFQHPITHAVLPQGFDYRIYQIEATAPILIAQSPSDDTPHSTKAGSVLLNPAIGDHTPRVCLDHTWPTVVCVHRTVQASMKARRITGGCFLSIAEWSRLQPAHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B956</accession>
    <name>A9B956_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5243"/>
    <dbReference type="EnsemblBacteria" id="ABX07870">
        <property type="protein sequence ID" value="ABX07870"/>
        <property type="gene ID" value="Haur_5243"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5243"/>
    <dbReference type="HOGENOM" id="CLU_2355869_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5305-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="9988" checksum="FF1751F5EFB0FD77" modified="2008-01-15" version="1">MKSFAYGLLSIIVFGLAVFAGPVAASYAAPVGGSAVVADEATHNQVGQLEAKIEDITEQLTTIGRPLAVLALVLVFISYVAEPVLPDWARDSATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B967</accession>
    <name>A9B967_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5254"/>
    <dbReference type="EnsemblBacteria" id="ABX07881">
        <property type="protein sequence ID" value="ABX07881"/>
        <property type="gene ID" value="Haur_5254"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5254"/>
    <dbReference type="HOGENOM" id="CLU_2329898_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5316-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10948" checksum="3271E22C9D87D816" modified="2008-01-15" version="1">MRTGIMKKPSMDAVEALCMFFPVEPAFFYPRLAALKNRQSGRSPAEQVKVALRSTSIDPSVQEHVAGIIQALTAHEDLKRKRDDDDEVEEGDSKEKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B985</accession>
    <name>A9B985_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5272"/>
    <dbReference type="EnsemblBacteria" id="ABX07899">
        <property type="protein sequence ID" value="ABX07899"/>
        <property type="gene ID" value="Haur_5272"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5272"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1832423_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5334-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="145" mass="16977" checksum="3E9557DE42EEFCF4" modified="2008-01-15" version="1">MTARWFADRITLYQLLHTHPGWSNRQLAMDTHRSIGWVKKWKARFGSPPHPDPQTVCQSQSRARKTPAAPWTERVITYILELRDTLSAQYNRIVGAKTILAYLQRDPDLASEPLPTSPVTIWKILRQHQRIYQRHAPLMWSRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB6</accession>
    <name>A9AUB6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0384"/>
    <dbReference type="EnsemblBacteria" id="ABX03035">
        <property type="protein sequence ID" value="ABX03035"/>
        <property type="gene ID" value="Haur_0384"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0384"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_3_0"/>
    <dbReference type="OMA" id="LLIFDWD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-387-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24106" checksum="3667FDB412A4BA90" modified="2008-01-15" version="1">MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWERLTDFQPENYGILTERYRTIYREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVSSAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFGLNATQALMIGDTIHDITLGHNAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF3</accession>
    <name>A9AUF3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0421"/>
    <dbReference type="EnsemblBacteria" id="ABX03072">
        <property type="protein sequence ID" value="ABX03072"/>
        <property type="gene ID" value="Haur_0421"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0421"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_831392_0_0_0"/>
    <dbReference type="OMA" id="ARDWVSD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-427-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="133"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="39093" checksum="7340FB1E3EBD39AB" modified="2008-01-15" version="1">MLAFWHTYQRVKHGSWSLVLGLALVACSIPVNYSSDNPPTSPPAELQIAAGFTITPIITGLDQPTGLAFDPQGRLYIAQRSGTVLISDGTNPPREYATDFNKPLSLHWYEQALYVVEQGQIQRLSDGNSDGIVDQQTVLLSDLPDQIEAATLVSDAQGWLYLGVGTRADHTATAGIQEGYIRRFRADGSESSVYATGLRMPFGLAFDPQQQLYATDNGREGLGDDLPPDEVNRITAGADYGWPRCWGQRQPDADGGGDAANCSTTNEPVALLPAHSGVTGIVFYQGTAFPARYHGDAFIGLSGSWYSQELRGHSIVRMDAETQQIESFASGFGRPVGLAISPQGQLLVADYDRGTIVMIAAPP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUH0</accession>
    <name>HRCA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hrcA</name>
        <name type="ordered locus">Haur_0438</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HrcA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AUH0"/>
    <dbReference type="SMR" id="A9AUH0"/>
    <dbReference type="STRING" id="316274.Haur_0438"/>
    <dbReference type="EnsemblBacteria" id="ABX03089">
        <property type="protein sequence ID" value="ABX03089"/>
        <property type="gene ID" value="Haur_0438"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0438"/>
    <dbReference type="eggNOG" id="COG1420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050019_0_0_0"/>
    <dbReference type="OMA" id="DYPGTMG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_1000092812" description="Heat-inducible transcription repressor HrcA">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <sequence length="354" mass="39218" checksum="200BD5702E1C95E6" modified="2008-01-15" version="1">MHLELNERRRRVLKAVIQQYIDTATPVASQDLARSLGVSSATVRNEMAALEDAGLLTHLHTSAGRLPTDAGYRFFVENLMDRAALSTQEQRMIQHQFYQIRSELNQWIHLAAAVLARTAQTAAVVTPPRAYESRFKHIELISINDALVLLVLVLHEGSVKQQTLPADPNTTQEQLSRIAGRINELCHEASAKAIANIAHNQSTNQPPLSSFEVLVIESVARAMQQFEEHVNELIHHDGLLEMLHQPEFGQVTRVREVLSILEGGTMLESLIPQALASDGVQVIIGGEHSRDELRDYSVILSRYGVNGDVAGVVGVLGPRRMAYPRSISSVRYIAGVMSDLMGDLYGERKIEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP9</accession>
    <name>A9AUP9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04576">
        <property type="protein sequence ID" value="ABX04576"/>
        <property type="gene ID" value="Haur_1933"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1933"/>
    <dbReference type="HOGENOM" id="CLU_152594_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1962-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15649" checksum="075833B791069EE1" modified="2008-01-15" version="1">MPYREKTAWLALIAIAVTYGPYFTLSAIFQPVDVPNLPQLGLFAATTISQLIILGVGHIYLGMKAPQDRRMPPDERDQAIQRRSFQSAYYVLMMGMIVVGGIMPFTEHGWTIVNAAIMIMVISEVVQYSVTVISYRRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR2</accession>
    <name>A9AUR2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1946</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04589">
        <property type="protein sequence ID" value="ABX04589"/>
        <property type="gene ID" value="Haur_1946"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1946"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_1_1_0"/>
    <dbReference type="OMA" id="INIRTVY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1975-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="36031" checksum="111FCD693EC1A467" modified="2008-01-15" version="1">MYSPTSRLLGVLELLQSRQQISGSELAQRLEIHPRTVRRYIQQLQDMGIPVEAERGIYGAYRLKPGQRVPPLLFTEQEILALSLGLLTIRELQFPVERATAETTLAKIERVLPAGLVQHARALQAAISIQLGIRSPRIEPAWLLQLSLAVQYCQQVQLEYLSAQQNMTERTIEPYGIVFNEGAWYLVGYCDLRRAMRVFRLDRIQAMRLLDSNFERPASIDIVEIVQAALNASDQPDEVEVLLKTTIEHARHIIPPAMGRLEATPQGVLLRRAAVHLEWVAFTLLELDIPVVVLQPAALRELLQAIATKALGMSNTAAPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV00</accession>
    <name>A9AV00_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3956"/>
    <dbReference type="EnsemblBacteria" id="ABX06588">
        <property type="protein sequence ID" value="ABX06588"/>
        <property type="gene ID" value="Haur_3956"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3956"/>
    <dbReference type="eggNOG" id="COG3677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033785_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3998-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009492">
        <property type="entry name" value="TniQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06527">
        <property type="entry name" value="TniQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="301" mass="35560" checksum="3B4B1206ED7C6313" modified="2008-01-15" version="1">MGHYFPSLYPGEIFYSVCARYLSHLRYTDKKFAKSELLQPYTISIYFPRNITALCDKYQIEIPSIEEIINKHTIFPLLRIFLSKEHAYLNNYKDPSKIWSIPALKSYIDTHKNYRLRFCKDCVIDDRKTYGEGYWHILHQVPWINICYKHSIFLHTPIYPRKNLINNFISLEDTLSKYKIKYLYKVRSILYMLSDTLFIFNEQPTISFDKISNSIRSIILDRGYTRTGISISHKALYNKIIDSYSKQTIDFLYSSKTISKKNVSIMIIQDNITRSRAVAYLVLSHLLGCTLQDIIKNCMNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV79</accession>
    <name>A9AV79_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0506"/>
    <dbReference type="EnsemblBacteria" id="ABX03157">
        <property type="protein sequence ID" value="ABX03157"/>
        <property type="gene ID" value="Haur_0506"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0506"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_0"/>
    <dbReference type="OMA" id="LRMERAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-512-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="377" mass="40808" checksum="1B6C621AD7F9F09C" modified="2008-01-15" version="1">MDYGFATRAIHAGQDPESVTGAVIVPIYQTSTYAQRGVGDHTGYEYSRTDNPTRTALQTCLAALEEAKHALVFASGLGASTTLMLMLKAGDHVICGDDVYGGTYRLFQRVMTEHGLSFDFVDMADPEAVRAAIKPNTRLIWLETPTNPLLKLAPIAAITKVAREHGIWTIVDNTFASPYNQRPITLGADMVLHSTTKYIGGHSDVVGGAIMTSNDELYEKLKFLQNAAGAVPGPFDCWLVLRGVKTLSIRMREHERNALAIAQFLTEHPAVEKVIYPGLPSHPQHNLAREQMRGFGGMISILLKGGAEVANAMVSKTKLFTLAESLGGIESLIEVPAGMTHMSVAGSKLEVPANLVRLSVGIEDINDLLRDLEQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV82</accession>
    <name>A9AV82_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0511"/>
    <dbReference type="EnsemblBacteria" id="ABX03160">
        <property type="protein sequence ID" value="ABX03160"/>
        <property type="gene ID" value="Haur_0511"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0511"/>
    <dbReference type="HOGENOM" id="CLU_1616758_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-516-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18699" checksum="26A9217EB1EC3BC3" modified="2008-01-15" version="1">MNRQQSDVPKPSLDQLIDDCFGYGIRLGTIIGGIYGFGLGVGFDIFVGLVAAIIGLIYGFFMGLIGSPIVAIIIYNWRKWFAANFIGNLGLWLITPIILSSLHCLSWYPFFAANYSLSEYIGLFFGRETQLFYFYIFIRYPNWLMSLLMLLFLPLFLDQLDSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB1</accession>
    <name>A9AVB1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0541"/>
    <dbReference type="EnsemblBacteria" id="ABX03189">
        <property type="protein sequence ID" value="ABX03189"/>
        <property type="gene ID" value="Haur_0541"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0541"/>
    <dbReference type="eggNOG" id="ENOG5032VZ2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908435_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-550-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021451">
        <property type="entry name" value="DUF3102"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11300">
        <property type="entry name" value="DUF3102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="33389" checksum="B7F444459EC5A0E2" modified="2008-01-15" version="1">MTTQLTLFDYNALDTETRVIVQQKAVEIRDRMRSAAQAVIEIGERLIDVKERLGHGKFGQWLDAEFQWSADTARNYMNVAERFGQNPKISEFAPSALYLLAAPSTPEDARTEAINLAEQGQKITHAVAKQIVTTHKEQAAPKPKPAAAPAVPKPEPKLEIPPMLIIGDKTVPSAEFTGTPTPNTIDDSESEELASQPLVETPSEQPDLPPMLTIGQPSPAAAVEIDTKPLAYAIVVQELARQMVTLANQRVKLLEDQIEAQGKEVIQPFIDTEQMAEAAASFIGTPAFKSQAGLLAFGVKVNLRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI8</accession>
    <name>A9AVI8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2036"/>
    <dbReference type="EnsemblBacteria" id="ABX04679">
        <property type="protein sequence ID" value="ABX04679"/>
        <property type="gene ID" value="Haur_2036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2036"/>
    <dbReference type="eggNOG" id="COG1372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_225868_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2065-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032869">
        <property type="entry name" value="WHH_dom_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14414">
        <property type="entry name" value="WHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732175" evidence="6">
        <location>
            <begin position="27"/>
            <end position="3073"/>
        </location>
    </feature>
    <feature type="domain" description="HintN" evidence="7">
        <location>
            <begin position="2824"/>
            <end position="2918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3073" mass="326057" checksum="A03FB610878FAB96" modified="2008-01-15" version="1">MPLLRRGRVWYALCLFCMLVPLFVHPATIQPVMAAPLVPASSTHQWTQATPTALLIANTADGITLTSADTALRQFLETTMGWTVTLKDDDLVQASDAAAVNVVVISASIDSYKLDNDFTYVTTPMVVNEYALYDQLGMTNGASGTDYGINSGTPTTTITLLDPTHPLAGGKSGTITVQSQSLRLPYGRPVNQGVKVANLPGSTSKTVLFGYDTGATMTIPSTKDGGLVGSTPLAAPARRVGLFLDADTPLYLTSDGWDLVRSALLWAIGQTPPSGTPTPTTVAPTATPAPETATAAPATATATSLPPTATATNLPPTVTPPSGAGKNLLLVVGSVPLGSGDAAVLQRLTDAQYTVQVIPQTSLTLEATQGMHGVLISSTVSASAIGMLLTTHPVPVLTWEYALYDDLRMTGTSSGTHFGTSTGSTLSIAAPTHPIAAGLSGVVSVSGSAVTLAFGQPLAQATLVAALPNAPASAGIFTYAQGAALSSGTAPARRAGFFFDNTSPTTATATGWALFERSVAWLIEGFTPIQPATATPTATVVPSPTPTASPTIVPSVTPVVPPSATPIPTATPLVIPPDPAAVAPALSAFTASDLFADTAFLYTGTTPIQTGVAPDTITAQRVAVIRGRVLDRTRQPIPGVQITIKDHPEFGMTHTRADGMFDLVVNGGSRLVVQYQHPQFLRVQRAVTTPWRDSVWTPEVVLTPLSPIVTTIQLGGAAQAAEGTVSTDDRGTRQARLFFPAGITATLRLPSGATQPLTSIAVRASEYTVGDTGRAAMPGELPSNSGYTYAAEFSADEALAVDGSVEFSQAVANYTENFMGFPVGMAVPTGWYDAQRAVWVPSPNGRIIAVLTTAPLTLDLTGDGVADDPASLGIGADEQAFVASTYSAGTSLWRVPMTHFTPWDHNWPFGPPDDAVGPNGGPLSSDPPISIPCEQPGSVITCETQSVGEEVALAGTPFRLVYTSDPAAAHHQEVVIPLSGATIPNSLTGIDVTVQIGGQQWTQAFSPSTNLATIFTWDGLDAYGRMLQGSQSATIKIGFTYPGQYRTPAQFGSAFGQFGTGGISLTGDRATEMITVERVLNTTLGRLHVSQNAIGGWSLDIHHQYDTHQRILYRGDGSRQRAEALTAVTRTGVGWAYPRLHAIAPTRDGGRYEAGGSGSISTNLWEWLPDGTRRQRSGILNGLPPADGQLLSHTEFNGIRALHTTPTGEVYLTDEGSTWGGNAPAIYRITADQRLERVVGGTTKALTLTPDGAVARTMPIGTPLAVDVDTDGTVWFIDAYTVEVPQANGPIIGKTVTALRVVRTDGQVIHPVAPTQLRCGFPNLRDEEIVHVTHDTRGNHYLALRGRYPAVAGPTGTGCILRIDAAGTITRIAGRDTNGQAIGQYPEGWLATESPLIDPNAVHVHSDGRLIVQDIGALREILPDGEMRTIVGNPSPSTDPQLDELFGSMVGPNGQISFTSRAVKQGTVAPPFPGVGQARLEVPSSDGSEVYVFASTGRHLLTRDAMTGVLRYTFLYDTAGRLTGVRDQHGQTTTITRIADGTPTAVVSPDGVTTTLTVGSDGSVQAINDPTQSRWQLQYQDGLLTRLIDPRNPDWQHQYTYTADGHLSQDIGATGGWTALDQTRLSATTTIVTSTTATGIMTAHRISTAADGTTSRMVTTEGRPTITTAIDAHGNQVLIDARGMRRTTTMAPDPRWGMTAPYPAAITVTNPAGQVVATATMHRSVVLSDPTDPWSLVTWQEVFTQHGLTTTTIYTAATRTRQVTLPSGVVRVTTYNAAGQPITETATDQAVKSWTYQPDGRLASDTIGTGPTAATTTYAYTPQGFIAAITNALGETTTYTHDAAGRIATVTHPTGHTRQYWYDAVGNRVQERDERGMVTTRVYNADNQPIAEVVDVHGRAILTTVTYDLHGRVVRESTAQGANRPPAVTTYGYASLSPVASVPISVTNALGETTTYTYDAVGDLVAVTDAMQHTTVMTYTPEGWLAAVQSPSGQLMQRDYTTDGQVLSETDARGSITTYTYTALRQPETVTVNTTAVAGYSAVAASTTTTYDGWGRVVRVRDPRQQVTTFHYTDRDHLAWTELPTGEQTHYTYDALGRPIATVVGAHDPSTAITTTTSYDAAGRVLTTVVDPDGMALTTRYRYTEPGASNSWDLHAVVDPNGHTTRYQTNALGWMTATTNALTETWTMTYDQRGNQTGITDPRGNTLAWEYDALGRRIMEHEAGRTQRWQYRADGRLAAQIDMANRTTSYGYSVDGFLTDIDYPSGTADVSYTHDANGNVTTMQDGLGTTTYRYDGLNRLRERTRDGRTVGYTYDAASFRTNTDYWGTGSVTATPDAAGRVASLQPWGGSTTTYAYGARGQMATATSGSGLSVTPTYDAAGRVLATHYAQNGTTLANFGSTVDAVGNRTSLTDANGTTTLTYDATDRMVQATEPQASTTYTHDAVGNRTNVATTGQTPFSFSYDAANRLTTSGYTHDANGNLTTTPEATYTYDAANRVTSSTTSAGTTTYGYDGWGNLVRVTTNGQVQDLVLDEAAGLPQVLGTVTANGTTRVARDPAGLVHQTSGGQVSTLLTDLVGSVRQGITPSGTTLFSQAFTVDGVPVAHSGSATSAFGFTGEWTNPLDGLVYLRARHYLPTMGRFIQRDTDAGSSMAPASLHRYAYVDNNPATWTDPTGHRKGLQPDGSWEPCQIILGDPEDQCSLGDYFDFPKSKSGDDLMTMLKRFGKRIENLPGDAIHGTIAFATDPVGTLLAIPGSVGSMSQNCLQGTFCYNYEALADCVWDVGGMAVGGGFGGAGMVDDLARFRGGAGYADDLRYLDDLADGACSFTPDTPVATPDGPQPIARLREGDTVLGYDETTQTTGSYSITALLIHDDPVVLDLTIDGETITTTPEHPFYVRGMGWVPAGDLEPGAAIRTASGTWGYVQISIARNMPQTMYNLTVADAHTFFVGDDQWLVHNAKCPKPRNSAYAGTTYYPKDPNVRARYPNGVPFDAQGYPDFSAYSIKDVQIDMRGNRGSDFAKADQAAGYTVRPSGYTWHHHQDRTTMQLVPTDLHGDVAHTGGVSMIRWFGILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVJ2</accession>
    <name>A9AVJ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2040"/>
    <dbReference type="EnsemblBacteria" id="ABX04683">
        <property type="protein sequence ID" value="ABX04683"/>
        <property type="gene ID" value="Haur_2040"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2040"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="OMA" id="WDQGRLK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2069-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="527"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="924" mass="99468" checksum="B56E8E219E54B224" modified="2008-01-15" version="1">MTNALPDAVLAKLHAVFPDLAAADLHAILERVLSGERVAIADKVLSVQTDRHGQAIALGCTVLGDLTQVVFQIHLPEPIDLLPAALERLATLPLETIPEPRMDLPARSHLDFRPNPNFVGRAAAFRDLAAALKRHQTAILTPAVAVGVGGIGKTSLAVEFVYRYGWYFAGGIFWINSADPTQIASHVAACAPALGIDPRGMPLDEQVHQVLLAWQAAMPRLIVVDNCDDAKVIDGWLPAIGGCRVLITSRSDQWASVPLVRVGLLSPRESRALVQRLCARLTDIEADAIAEDVGYLPLALHLAGSYLTAYSHHTVEQYRKDLTIAHRSLKGRGALRSPTRHEQDIEATFMLSFNQLDPTNALDALALGMLDGAAWCAPGVPIPRDLVLAFVPDETDADDAVDALRRLQQLGLLDGADAVVLHRLLAQVVEARLGSTETLAMVEDRIDAVASRVNEMGVPRSMLSLEPHLRHTTTRALKRGDALAALLANNLGYFEALRGAYADAQPLYERALAIREAVLRADHPDTAQSVNNLASVLLHQGRYADAQSLFERALAVRETVLGADHPDTATSVNNLAFVLERQGRYADAQPLFERALAIREAVLGADHPATAVSVNNLAGVLLRQGRYADAQPLFERALAIREAVLGADHPATAVSVNNLAGVLLRQGRYADAQPLFERALAIYEAVLGADHPDTAVSVNNLAGVLDRQGRYADAQPLYERALAIYEAVLGADHPDTAVSVNNLAGVLDRQGRYADAQPLYERALAIREAVLGADHPDTAQSVNNLAMVLASQGRYADAQPLHERALGIYEAVLGADHPATAVSVNNLAGGLARQGRYADAQPLFERALAIYEAVFGADHPDTAVSVNNLAEVLERQGRYADAQPLFERALAIYEAVLGADHPDTQFIRANLVSLQATMTADDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK8</accession>
    <name>A9AVK8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2058"/>
    <dbReference type="EnsemblBacteria" id="ABX04699">
        <property type="protein sequence ID" value="ABX04699"/>
        <property type="gene ID" value="Haur_2058"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2058"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1419743_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2086-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20584" checksum="EC02639A4D2FA52B" modified="2008-01-15" version="1">MPQPTIAVVNSDPALLALLDELLTETDYTVTTYLTEATTYPALQKLQPDQIILDVGMQAAAAGWPLLKLLQFDPSTMHIPVLVSMVDHQFVRDKADFLATKGYHVLELPASFATLATVVRAILEPEMSDPPAPSGSDLPAQGWRGRGRSTTLTLHRSIVGGFMNTVRFFPIRVMGIGIIFALGGLAAVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL1</accession>
    <name>A9AVL1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04702">
        <property type="protein sequence ID" value="ABX04702"/>
        <property type="gene ID" value="Haur_2061"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2061"/>
    <dbReference type="eggNOG" id="ENOG5031EHN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313995_0_0_0"/>
    <dbReference type="OMA" id="FKSGMAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2089-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021683">
        <property type="entry name" value="DUF3267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11667">
        <property type="entry name" value="DUF3267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="22944" checksum="816F5C6AB716429A" modified="2008-01-15" version="1">MRKHSSPIPPPENLPTAYQEVLSWNVSTRPRRVLLAHTLAVLSFCLFGVLFAFGAVSVGKQPLSGSFALGLREAVALMVGMLLTLMLHELIHGVAMQLYGAHPRYGILWRRMMLYATDPAYAHPRNRYIVIALAPFVCISTLVVLAMWAFAGTAWVPLLAICGVINASGAAGDMWMTLIVLRYPPSAYIVDERDGIRVFCQSTVGMDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL2</accession>
    <name>A9AVL2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04703">
        <property type="protein sequence ID" value="ABX04703"/>
        <property type="gene ID" value="Haur_2062"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2062"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_2_0_0"/>
    <dbReference type="OMA" id="GWIKELN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2090-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="257"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="397" mass="44178" checksum="259C2C17CA35CFFC" modified="2008-01-15" version="1">MAKLPVTVLSGFLGAGKTTVLNHVLTNRAGLRVAVIVNDMSEINIDAQLITEGTAQLSRTKEALVELSNGCICCTLRDDLLREVARLARDGRFDYLLIESTGISEPLPVAMTFSFETPDGIDRLVDIAQLDTMVTVVDAHTWLADYRAGQALHTLDMGISPADHRTIADLLIDQVEFANVIVLNKIDLVDTRQLHELEGVLHTLNPDARVLHATNGVIEPTAILHTGLFDMERAQQSAGWIKELNGEHTPETEAYGIGSVVFRARRPFHPQRLLSVLTGPELQPVLRSKGVLWLASRHDHGLRWSLAGKIARVSDSGAWLAATPDDTWPQNDQVGIYIERYWQEPFGDRRQELVFIGIDMPHEQLVAKLEHALLTDQELAAGPPLWKRFEDLFPHFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM8</accession>
    <name>A9AVM8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3996"/>
    <dbReference type="EnsemblBacteria" id="ABX06628">
        <property type="protein sequence ID" value="ABX06628"/>
        <property type="gene ID" value="Haur_3996"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3996"/>
    <dbReference type="HOGENOM" id="CLU_2601260_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4038-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="79" mass="9098" checksum="34E811C67AE89FBF" modified="2008-01-15" version="1">MVHLDDATKRLELVRYHMQQGWQIDAPVLGRHAYLDQRGSIRAVEVVLSRSEMRQVVALPDTASVREFLHQYGLNVIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ5</accession>
    <name>A9AVQ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4023"/>
    <dbReference type="EnsemblBacteria" id="ABX06655">
        <property type="protein sequence ID" value="ABX06655"/>
        <property type="gene ID" value="Haur_4023"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4023"/>
    <dbReference type="eggNOG" id="COG1988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125861_0_0_0"/>
    <dbReference type="OMA" id="FTVWIPL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4065-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="20269" checksum="FDA9356CD4C986BB" modified="2008-01-15" version="1">MPTIFSHVAPALIVGLALGRERMSRPLLICASIAAISPDFDGISFWLDMPRGTLLSHRGFTHSVGFATIIASMGASFAPRLGCKRWVAGLTLFLAVLSHPLYDMLTNGGSGVALWWPFSSQRVFFDWRPIAVAPISAARLFSARGWNVLLSELTWIWLPWLGIGLMLAWLRRQYDTSKAQMHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU7</accession>
    <name>A9AVU7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-amylase</fullName>
            <ecNumber evidence="6">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A9AVU7"/>
    <dbReference type="STRING" id="316274.Haur_4065"/>
    <dbReference type="CAZy" id="CBM20">
        <property type="family name" value="Carbohydrate-Binding Module Family 20"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06697">
        <property type="protein sequence ID" value="ABX06697"/>
        <property type="gene ID" value="Haur_4065"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4065"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013336_3_0_0"/>
    <dbReference type="OMA" id="FRYAYDL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4108-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="8">
        <location>
            <begin position="496"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="596" mass="64608" checksum="E03E668B49AB2662" modified="2008-01-15" version="1">MSRTTRAMARLTLFVLVVIIFSVGFFGTAPRATQAQTTPRTAFVHLFEWKWTDIAKECENWLGPKGFAAVQVSPPQEHIQGSQWWTRYQPVSYQIQSRSGTRAEFANMVSRCKAVGVDIYVDAVINHMTGVGSGTGVAGSSYTSYNYPGNYQTQDFHHCGRNGNDDISNYQDRWEVQNCELVNLADLKTESDYVRGKLAAYLNDLRSLGVAGFRIDAAKHMPAADIANIMSRASNPYIYQEVIDQGGEPITSGEYTGNGDVTEFKYSTNIGRMFKTDKLANMSNFGTAWGFIASDSAVVFTDNHDNQRGHGGAGNVVTFKDGKLYELANVFALAWPYGYPQVMSSYNFSNGDQGPPSSNVYNGNTADCGGSNWVCEHRWRGIANMVGFRNYTSTAFSTSNWWSNGNNQISFSRGSLGFVAINREGSSLSRTFATGLPAGTYCDVIHGDFNNGSCSGPTISVNSSGQATITVAAMDSVAIHGGAKINGTNPTPVPTTPPSGSIAVTFNENATTVWGQNVYVIGNVSALGSWNTANAVLLSSASYPVWSKTINLPASTAIEYKYIKKDGSGNVTWESGSNRTFTTPSSGTVTRNDTWK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV2</accession>
    <name>ATPA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="1">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpA</name>
        <name type="ordered locus">Haur_4070</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AVV2"/>
    <dbReference type="SMR" id="A9AVV2"/>
    <dbReference type="STRING" id="316274.Haur_4070"/>
    <dbReference type="PRIDE" id="A9AVV2"/>
    <dbReference type="EnsemblBacteria" id="ABX06702">
        <property type="protein sequence ID" value="ABX06702"/>
        <property type="gene ID" value="Haur_4070"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4070"/>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010091_2_1_0"/>
    <dbReference type="OMA" id="LQAPGVM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000143393" description="ATP synthase subunit alpha">
        <location>
            <begin position="1"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="175"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="1">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <sequence length="517" mass="55514" checksum="028DCAA06F744217" modified="2008-01-15" version="1">MAVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTKSGETVMGIALNLEKDNVAAVILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRPLDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAIDALIPIGRGQRELIIGDRQTGKTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAALQYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLSEVNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLESDLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLELAQFRELAAFAMFASDLDAGTKAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHSSYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW7</accession>
    <name>A9AVW7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0557"/>
    <dbReference type="EnsemblBacteria" id="ABX03205">
        <property type="protein sequence ID" value="ABX03205"/>
        <property type="gene ID" value="Haur_0557"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0557"/>
    <dbReference type="HOGENOM" id="CLU_1945813_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-566-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="14083" checksum="C3F9D7DA17CFA12D" modified="2008-01-15" version="1">MSTKVKVTLTDSWMHLGTTYLPGVHTLDESIANILVAANATTDVQSIEPVAAEPVQRVEQPATPNADGDAGTPTTDGGQAPAEPSVELVSVVGSKAAASLAAAGYTTYGDAVAADDATLSAIDGIGEATIKKLREYKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX8</accession>
    <name>A9AVX8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0568"/>
    <dbReference type="EnsemblBacteria" id="ABX03216">
        <property type="protein sequence ID" value="ABX03216"/>
        <property type="gene ID" value="Haur_0568"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0568"/>
    <dbReference type="HOGENOM" id="CLU_2584928_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-577-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="9316" checksum="57667CF298CAD489" modified="2008-01-15" version="1">MWDMWDMWDKVMKFQIFYCSHCGTPLGFIPHDGFALICGIACITTTTPITCGACKNQTIWYAPKRQRRKKQRLGIVRQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW50</accession>
    <name>A9AW50_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03288">
        <property type="protein sequence ID" value="ABX03288"/>
        <property type="gene ID" value="Haur_0640"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0640"/>
    <dbReference type="HOGENOM" id="CLU_972453_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-651-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="32730" checksum="118473B0162BCBBB" modified="2008-01-15" version="1">MKVNNLLSSVAGISYKSISGYTFEKYGAIMTTSPEVQAALIAGIVAVFGTIITMIIAKRTFKSDKEKIMIEQQKLDNDRKRMDAEIAKLNIETEKTIIDAYDIRNLQSAEVSKLIAETKKTLYEMNHIKNTQIINDAEKIRNLLILFDRKAFNKLVSSEDPLLLLRAIIETRINMQKMGASFIYDIEVSNAFNNIKNILIHLEDWVSQNIPKLNELAEDIEIRKYHGVSPDTFKGINPYEFVDKVISARSDINRNLHIVEKNFREIEQQTRNQPDEPVKPLDDLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW79</accession>
    <name>A9AW79_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2089</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2089"/>
    <dbReference type="EnsemblBacteria" id="ABX04729">
        <property type="protein sequence ID" value="ABX04729"/>
        <property type="gene ID" value="Haur_2089"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2089"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_13_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2117-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1025"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1363" mass="151514" checksum="9B2900BF37DD488E" modified="2008-01-15" version="1">MTQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEPGNPAYNILFAVQIDGPLHVAYLQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLTIVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFDLAQGPLLYGRLLWLAEQQYVLILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVLAAQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATMFMLLLAAFQLMLARYSQQQEFVVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFREFLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQVMFVLQNTPKVNYEIADLQLSFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPDQALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQALQQRAMALAAQLQQHGVRQETLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRSAQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIEQWNDAATKLVVSQTHPQQLAYTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGLLVGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRWVLPTGEALQPVQARQWFATYPQIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPVANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPARTASAFVPNPFADNGSRLYRTGDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYLVPVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQTPLVVPRTQHEAELAAIWADVLQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPLRMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTPLVCVHAIAGTVGCYSELAIALNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMARQLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPAEQQLAALYQQAQQAGLIDRDLPFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQANPAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIEQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW86</accession>
    <name>A9AW86_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2096</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2096"/>
    <dbReference type="EnsemblBacteria" id="ABX04736">
        <property type="protein sequence ID" value="ABX04736"/>
        <property type="gene ID" value="Haur_2096"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2096"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_3_2_0"/>
    <dbReference type="OMA" id="PVRFAMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2124-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="28220" checksum="197F48F3EEC4292D" modified="2008-01-15" version="1">MNSVEFIDLLRLLPVQRAIIALIVAGSAFPIIGVWIMGLNILPVRFAMMHVALFGIALGLLLGIEPTLIALLVCGASGASLAPLAHRPAGLAGPMGIVMTMAIASALLLLSQTGINANGAFELLWGSILATRQSDLIVLVVVSIGILGVYGWQRRDIALLLYDREIALCSGIAVDRLTMGLLIIIALSIAAAVRLTGALLVDAITILPAIAARNLGQSLGSMIAWAMAIGVVGNLVGFCLTLMFNQPPGPMLVITVGCITILSYLRKEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW94</accession>
    <name>A9AW94_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioester reductase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2104"/>
    <dbReference type="EnsemblBacteria" id="ABX04744">
        <property type="protein sequence ID" value="ABX04744"/>
        <property type="gene ID" value="Haur_2104"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2104"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_76_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2132-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="67"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="58208" checksum="407507D5712FD5A5" modified="2008-01-15" version="1">MNLINKVNSAAALPLREYLQHHLPESMLPTAFVELRQIPRLPNGKVDRAALPTIDFQQYSDPEHYVAPRTTTEQQLAYIWQQTLRVPQVGIHDNFFALGGDSITSIQVAARANQAGIRLTARQLFEQPTIAQLAHGVAITDQRNLLDEIVLDPAINPLGLAPYHEHMPQSILLTGATGFLGPYLLAELLTQTSAHIYCVVRAADETQAFAKIRQQLEHANRWEPAFASRLIVMLGDLSLPQLGMTAADWQMLAQTIDRIYHNGAVVNLAHSYAQLKASNVQATIDLLRLASQVKLKSMHFSSTTSVFPANTAATVRYEQELPSTPDGLITGYAQTKWVAEHLLLQARARGIPINCYRPGRIGWDTQTGQWNRGDGLYRLLQGCLQLGRAPLVDRLAEITPVAYVAQAMVALSLQPSGQGQTYHLVNQQHIAWNQLINWMQELGYPIEQVDLDQWMLQLQRQTKDVPNTSLQSLLTLAQAAVNGPHAEQAYDQTAMQAALAATEVMLPTLDRTSLQQWLAQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG2</accession>
    <name>A9AWG2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4089"/>
    <dbReference type="EnsemblBacteria" id="ABX06721">
        <property type="protein sequence ID" value="ABX06721"/>
        <property type="gene ID" value="Haur_4089"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4089"/>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686571_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4133-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="133"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="401" mass="44484" checksum="F5C86B61B2302FBD" modified="2008-01-15" version="1">MVQPYPLTNRGRMPSIPALAQWINTILLTAVPTLSPWTARRLTDWLLSILLMPSITTRVVAWGCALGLSTAARAASHERRLRRTYRDSQLSWSLHRAILTTTLRFAPAEAVTVIIDETTHTDHWTLLTAALWYHGRAIPLAWVLHPGNTRRTTAFWMDTATLLDRVQQVLPATTDVVVVADRAFGCPAFTDQVAAHGWSWVVRVQGHTRMLLRGHTEVPIRTLVGRGQRVVRRGQAFKKAGWRTVTVVAEWTAVAQEPLLLVSTLAGIGAIRHAYGRRSAIEALFRDWKTGGWQWEASQSRSQTTQDALVLGMAIATVLVLLVGTAEAQAVLAERGDRPSPRRPWAARESLFRLGRYGVLRWLWTGTQPALGARLSLAGTALHERWATTVTRGGRLGTAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWJ2</accession>
    <name>A9AWJ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4119"/>
    <dbReference type="EnsemblBacteria" id="ABX06751">
        <property type="protein sequence ID" value="ABX06751"/>
        <property type="gene ID" value="Haur_4119"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4119"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_0"/>
    <dbReference type="OMA" id="PPAWAYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4165-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="48171" checksum="A668C03C6D800A15" modified="2008-01-15" version="1">MKRRLAPQAGCPPGSFGAPVIGEIREWAADPLQFAQARAQRYGPIWSTHLLGRPCVVLLEPAGNRFMLSQGLQYFSWRAGWGRAMLRLMGGGLSLTDGHQHDQQRSLLKPAFAHAALQQLQPQIQHLIRQQLQTWPDAEPICLLERLQTLAFDVALLVVCGRTPAPIAEALHHDFAAFTAGLFTPLPYPIPATPYFRAQKSGERLRQTLSYLIELRRLNIAADALDSLSLMLQAEPNRPDDELISELLLLLWAGHDTVASLLTWICIELAQHPEILQRLRQELSTNHHSLLDHVLREAERLHPPAPGGFRGVVEAFEYAGYHVPQGWLAMYSSVYTHQMPSLWHNPTQFNPNRFAAPCNEGKQAYSLVGFGGGPRICIGLALAQIEMRLVLRELLANYQWQLVPNQDLRPVWLPTNQPRSGGLITIQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX01</accession>
    <name>A9AX01_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LamG domain protein jellyroll fold domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2169"/>
    <dbReference type="EnsemblBacteria" id="ABX04809">
        <property type="protein sequence ID" value="ABX04809"/>
        <property type="gene ID" value="Haur_2169"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2169"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_224181_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2197-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044060">
        <property type="entry name" value="Bacterial_rp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18998">
        <property type="entry name" value="Flg_new_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1097"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1134"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1168"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1220"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1253"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1287"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="1724"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="2391"/>
            <end position="2531"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="2690"/>
            <end position="2817"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="3002"/>
            <end position="3136"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="3483"/>
            <end position="3610"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="3704"/>
            <end position="3836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4257"/>
            <end position="4277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="4357" mass="460655" checksum="D7C3B3AECE079C2A" modified="2008-01-15" version="1">[encoded data, 4357 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX27</accession>
    <name>A9AX27_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrin alpha beta-propellor repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2195"/>
    <dbReference type="EnsemblBacteria" id="ABX04835">
        <property type="protein sequence ID" value="ABX04835"/>
        <property type="gene ID" value="Haur_2195"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2195"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025051_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2223-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="676" mass="69340" checksum="8A349E8FB2D0D63C" modified="2008-01-15" version="1">MLSSSWLMHWSRRSIWILLFGLLSMGVGFGSKPAPSTAAALFTATDWRAIRALLPLRQQAYFKPSQVSADDAMGWSIAVSGDTIVVGAPHEDSSTAGVQNGTTPTVDEVASDAGAAYVFVRTGTSWSQQAYLKASQVAAGDGFGTSVAVSGDIIVVGAPHEDSGTVGVQNGATPTIDEAASDAGAAYVFVRTGTSWSQQAYLKASQVSAGDDFGASVAVADTTVVVGAHQEDGSTTGVQNGATPTVDEATSDAGAAYVFVRDGRSWSQQAYLKASQVSAGDIFGASVAVADTTVVVGAHQEDSSTAGVFHSAAPTVDEAASDAGAVYVFVRDGTSWSQQAYLKASQVSAGDIFGFSVAVAGETLVVGAPYEDSSTAGVSNSATPTVDEDMTNAGAVYVFVRDGTSWVQQAYLKASQVSAGDIFGFSVAVAGDTIVVGAPHEDSSTSGVSSSATPTVDEAMSDAGAAYVVVRNGTTWVQQTYLKAAQTSVSDIFGFSVAVAADTLVVGVPYEDSSTAGVDHSTLPTVDELASDAGAVYGFTNLPTLYLPFVTTSQPLVIAPLTPVAVPTTPVGTPGMIFLTKTITLPTPLSSSGHYWLSASPTALVPGLVDDAVILRVGSTEILRHHYGMTGELQAALVVVPVGDLLPWAGQTITVDFTDISGLVYSTTPLYLVWTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX85</accession>
    <name>A9AX85_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4173"/>
    <dbReference type="EnsemblBacteria" id="ABX06805">
        <property type="protein sequence ID" value="ABX06805"/>
        <property type="gene ID" value="Haur_4173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4173"/>
    <dbReference type="eggNOG" id="ENOG5032RWC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129874_2_2_0"/>
    <dbReference type="OMA" id="ANETDYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035652">
        <property type="entry name" value="CHP02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="14148" checksum="90F540E367B6CF97" modified="2008-01-15" version="1">MERQDLQARTKKFALHIIQLVNFIPNSLAGRVLAQQILRSGTSVGANYREACRARSAAEFISKTNIALQELEETRYWLELLQESTLLDHRQCHHLVDEVQQLIAIFVTVIKRKKQHSNLDPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX94</accession>
    <name>A9AX94_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyrimidine-nucleoside phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4182</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4182"/>
    <dbReference type="EnsemblBacteria" id="ABX06814">
        <property type="protein sequence ID" value="ABX06814"/>
        <property type="gene ID" value="Haur_4182"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4182"/>
    <dbReference type="eggNOG" id="COG0213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025040_0_1_0"/>
    <dbReference type="OMA" id="DVWRRMI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4229-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="434" mass="45798" checksum="A86536E33267FA47" modified="2008-01-15" version="1">MRAVDLIIKKRNGAQLSTEEIQWLIQGYTNGSVPDYQMAAWAMAVVLKGMDDRETTDLTLAMAASGDQLDLRDFAPDAVDKHSTGGVGDKTSLVLGPMLAAVGLQVAKMSGRGLGFSGGTLDKLEAIPNMRIDLSEDEFRHAMREIGMVIMGQTADLAPADKKLYALRDVTGTVECIPLIAASIMSKKLAAGAKSIVLDVKVGAGAFMKTLDQARDLARTMVRIGQLAGRNVAAILSSMEQPLGLTIGNALEVREAIETLQGRGPGDLVEVCLTLGSHLLVLAGKAQNLDDARQQLQASLDNGQAWAKFREFVAQQGGDLTVIDQPETLPIAPIQISLLAESSGFVQRIDAETCGIVATELGAGRARKEDAIDPAVGLVLERKVGEPVQAGEALLTVHAADQQRAEVALAALKSAITISATSVEALPLVFESVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ7</accession>
    <name>A9AXQ7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11 12">Uridine kinase</fullName>
            <ecNumber evidence="7 11 12">2.7.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytidine monophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Uridine monophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">udk</name>
        <name evidence="14" type="ordered locus">Haur_0823</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11 12">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 11 12">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11 12">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 11 12">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="7 11 12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0823"/>
    <dbReference type="EnsemblBacteria" id="ABX03471">
        <property type="protein sequence ID" value="ABX03471"/>
        <property type="gene ID" value="Haur_0823"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0823"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021278_1_2_0"/>
    <dbReference type="OMA" id="TTLKPMH"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00551">
        <property type="entry name" value="Uridine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026008">
        <property type="entry name" value="Uridine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="13">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX03471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="24816" checksum="0C7E6F0618C54C0F" modified="2008-01-15" version="1">MSAEQRPIVIGVAGGTGSGKTTVSQAILSRVGPSRIAFLQHDSYYRDFAELSFEERLRVNFDHPNSLDSNLLAQHIEALCNGTTIEVPIYDFTHYSRRPEVMHVQPRPVILVEGILIFAEAVLRQCMDVKIYVDADADLRFIRRLKRDIAERGRSIESVIEQYTNTVRPMHLEFVEPTKRYADIIIPRGGLNAIAIDMVIARVEYLLAESEKVSMKAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ8</accession>
    <name>A9AXQ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03472">
        <property type="protein sequence ID" value="ABX03472"/>
        <property type="gene ID" value="Haur_0824"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0824"/>
    <dbReference type="HOGENOM" id="CLU_2569160_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-838-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="9261" checksum="271C16F97AEAC92F" modified="2008-01-15" version="1">MPKSDYRRGVRDQYYDSPPTINDLLNPDYERGRSRIVLVSQESNDLSGLIDIAFLLLGLLLKPILHTIVVCFLAYSLSMPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS3</accession>
    <name>A9AXS3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2249"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04889">
        <property type="protein sequence ID" value="ABX04889"/>
        <property type="gene ID" value="Haur_2249"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2249"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_0"/>
    <dbReference type="OMA" id="HTMAKVK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2277-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="220"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="47057" checksum="67E948FAC9E74AAF" modified="2008-01-15" version="1">MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNLAPNVRVFAVRVGPAAPYDKNWVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALELRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERMLLHEVDRVVAATPLDRAQMLEHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLLRSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQDQRKLPLFYSAADMVVVPSHYESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPREDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVAHDIRELYDHVVCGEPYADVVGAM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXU9</accession>
    <name>KDPA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kdpA</name>
        <name type="ordered locus">Haur_2275</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KdpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AXU9"/>
    <dbReference type="SMR" id="A9AXU9"/>
    <dbReference type="STRING" id="316274.Haur_2275"/>
    <dbReference type="EnsemblBacteria" id="ABX04915">
        <property type="protein sequence ID" value="ABX04915"/>
        <property type="gene ID" value="Haur_2275"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2275"/>
    <dbReference type="eggNOG" id="COG2060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018614_3_0_0"/>
    <dbReference type="OMA" id="RQGWAIL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-0633">Potassium transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000114686" description="Potassium-transporting ATPase potassium-binding subunit">
        <location>
            <begin position="1"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <sequence length="579" mass="61120" checksum="BA664BA011494719" modified="2008-01-15" version="1">MISNSVIQIGIFLVVLMACVVPLGRYMAKVYGENPPLQGFFGPIERLIYRLLGIDAKSEMHWKHYALALLGFNAMGMLLLYGLQRMQAWLPLNPQQLPAVSADSAFNTAASFVSNTNWQGYAGETTMSYLTQMLGLTVQNFVSAATGMAVLIGLIRGIARRSTSTIGNFWVDLTRSTIYILLPLALVLSVTLVSQGVVQTFSPSQTVELIQPIVNADGTTISQQTIALGPAASQIAIKQLGTNGGGFFNVNSAHPLENPTPLSNFLELLSILLIPAALCYTFGLMVGDKRQGWAILATMTIILLGFTVLAVSAEQAGNPLYQKLGVDDQASALQAGGNLEGKETRFGIVNSALWATVTTAASNGSVNSMHDSYTPLGGLAPMVLMQLGEVVFGGVGSGLYGMLIFAIIAVFVAGLMVGRTPEYLGKKIEAFEMKMAALIILIPCVMTLLITAIAVSSESGRATVFNSGAHGFSEVLYAATSAANNNGSAFAGLGANTPFYNTWLGIAMLVSRFWLIVPTLAIAGSLAGKKLIPQSAGTLPTHTPLFVSLLIGVVLIVGALTFIPALALGPIVEHLLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY52</accession>
    <name>A9AY52_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thymidylate synthase complementing protein ThyX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4302"/>
    <dbReference type="EnsemblBacteria" id="ABX06934">
        <property type="protein sequence ID" value="ABX06934"/>
        <property type="gene ID" value="Haur_4302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4302"/>
    <dbReference type="eggNOG" id="COG1351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024745_0_0_0"/>
    <dbReference type="OMA" id="MHRHRRC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4354-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="538" mass="60352" checksum="EBB8842C1D50F7F3" modified="2008-01-15" version="1">MHDPWGDTFTADEQAILAPFVTNLDQPIFGLRNLPEVVKGALFSRYSRSDKSLRRMLLDEFIQAPEAGFQAIVGHAAANGNDQLVATKQAEAFYERVLLGYGDDSVAELGGAHVACEGVSNIVAKALEDSRLGLDPLEKSTRYVPFDRQVAGKYRYHRVAELMQSPHATLYEQTLDQLFDTYRVLIEPVQRWVQSATPRDAKTSERAYVSATRAKALDLLRGLLPMATLTNVGLFGNGRAFEYLLTKLASSEHSEVCNVGVNLQHELDQLIPSFVKRAKTERGAAYSQYLATMRQAGAAFQPEIPTSNDLQAVTLVEFDPDAEAKVVAAILYPHSDQPLETLQCWARNLPTEERSAIIRAYVGERGSRFHRPGRAFEETYYTFDFLADIGAYRDLQRHRILTQERQRYSVVHGYAVAPELEAAGVAAAYCTALDQTAAAVQAIEADFPAAAQYLVPFAYRIRWRFRLNLREAYHLIELRAAPQGHPSYRAIAQQMYLALQKIHPSLIEGMQFVDLGEHALERLAAEQRFDQKLAERQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY68</accession>
    <name>A9AY68_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4318"/>
    <dbReference type="EnsemblBacteria" id="ABX06950">
        <property type="protein sequence ID" value="ABX06950"/>
        <property type="gene ID" value="Haur_4318"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4318"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_4_0"/>
    <dbReference type="OMA" id="IHQFRKD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4370-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="157" mass="18008" checksum="67C1A65B3F47AE25" modified="2008-01-15" version="1">MEDEHRSSLLSSISDMIRQLTWLSHRQSSQTMERLGLTLSQAILLIALDAHQGRATMSDLGRITQHAPATLTGIVDRLIANDLVDRERDEQDRRVVFVELTDAGRKKIEAINAERYRDMSQLMEQFNNQELELLSSIVERFVHELARLDAANYHGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI8</accession>
    <name>A9AYI8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0922"/>
    <dbReference type="EnsemblBacteria" id="ABX03570">
        <property type="protein sequence ID" value="ABX03570"/>
        <property type="gene ID" value="Haur_0922"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0922"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013885_0_0_0"/>
    <dbReference type="OMA" id="WEWIRAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-936-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_N" evidence="1">
        <location>
            <begin position="157"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="895" mass="101184" checksum="31CCC1742F476A0F" modified="2008-01-15" version="1">MTDVYQSSIVIAADQPVQPTWQPASPVLVRLAGTSYNHLHNLKFERTIGLFQVILRQQRWLDNHTQAIVDVLYTLIGTTQGSLKSSLVALKRDIFNRRLPLRSDVASLRNLEHPSLRGQVLRFRRTLQQLQRAWREARLVFEQELQAKRRLLQQSYAQPAFQKAVQVASSTLASSLPRYINADPSQLRSRERKTEVGAYQYLMRMAGKTSPFSHFGPLVLGSADPTLAQPIVIEGQMPQARAVSQLRRSVVGAIRNALVRIPAIKAYLPLRLNPSSFVDGESLVFSRLRQQLDDPNQYFASWQRRGKRSLLLDSVLAVFANQQQLSYAELLELLQTQHPELSSAKLAQTINQLLTSGLLFYNLDLPSDYRDPVLVLIEQLADVPSAEAGQIRELLQRLAESAQAYAQATVAQRWQLEQSMRQIVDQILAFAPELKQTSSQLGPLIVEDVVWDDVAVHLGQPLLASLASDLAPVLECGFQRDGRGPAQSWLLDIFTHAFGEGGQTDTILGFAPEYNRLSANSGELPMPRINAIQQRQRRYGQFLHQALDAEREARECVLDPHAFWQLAADFGQHNHYGSTSIQFQVAASSQTALEQGDYLVVLNYTLPGFGRFLTRYLSLLPAPSWQTYVQSAWQPLHNDAQAVPAEIVSVLEHNAQVHVPFTANVIVPPDEPSYRSQAIQHGVGDLSLAHDPVADQLRVYHRHADGSQQELLPLYMGFLHMVSLPILQRVLAQLSPSSYHMEQLRPREQTLVSRKQPTNAISHTPRLRIGRLVLQRESWNVPTAAIPSSVANDEFMSFFNWYSWAEQAGLPSEVFVRIQRPLSSKHLNMWTNHKPLALDFENYFSIQMLRHVIADDQVSLTLEEMLPSPQQQWFDLDQQPYVIEFQVEFNRGGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ4</accession>
    <name>A9AYQ4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-galactosidase</fullName>
            <ecNumber evidence="6">3.2.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2392"/>
    <dbReference type="CAZy" id="GH35">
        <property type="family name" value="Glycoside Hydrolase Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05032">
        <property type="protein sequence ID" value="ABX05032"/>
        <property type="gene ID" value="Haur_2392"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2392"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408695_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2420-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="5">
        <location>
            <begin position="10"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="672" mass="75826" checksum="6765EB7DD275D332" modified="2008-01-15" version="1">MSVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHETAPGQYDWGQIDPRKDLAAFMRLCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQARTVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDHMCQVIVPQLAPHGPIVAVQSDNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDADIASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAMEANGHVDWVGINYYRQPQGFDGAITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEFVTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYAQLFERLMGFLQQQQWWNFQRKPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQSWYGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATVWLGPTLPTLDEYFQPCTILADQLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQNPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLTSLWGAFAGADLQQQQPISLAAYTIAIVEVQHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU1</accession>
    <name>A9AYU1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05069">
        <property type="protein sequence ID" value="ABX05069"/>
        <property type="gene ID" value="Haur_2429"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2429"/>
    <dbReference type="eggNOG" id="COG3304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1330420_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2457-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="23161" checksum="27B8414883EA79E3" modified="2008-01-15" version="1">MECFECGETINPNLRYCLHCGVSLEAMYAAPPTMPADKLPPLPLFMQAAPQPVTVAAARVQPISQPEMNYQLPVIEQLRANIKDPNFLMQVIYFLVIGFWSSQMWLVATWVCALLGLNITQPMLNYLPTITFLSLPHTDGLVTSLRKELPRGLCLLYGICVGWYLSMLWMQVIWLATVSVVGLPLAQKMGRLLPSVMWLKPLPKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYW3</accession>
    <name>A9AYW3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KTSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4371"/>
    <dbReference type="EnsemblBacteria" id="ABX07003">
        <property type="protein sequence ID" value="ABX07003"/>
        <property type="gene ID" value="Haur_4371"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4371"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174765_0_1_0"/>
    <dbReference type="OMA" id="RYIRNSF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4425-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025309">
        <property type="entry name" value="KTSC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13619">
        <property type="entry name" value="KTSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KTSC" evidence="1">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="71" mass="8114" checksum="EB5451AC11EA644E" modified="2008-01-15" version="1">MKRTPVTSSNLASVGYDPTTQTLEIEFKNRSIYQYVDVPENVYNELMQAASHGSYFNGCIRGAFIYRKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX8</accession>
    <name>A9AYX8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4386"/>
    <dbReference type="EnsemblBacteria" id="ABX07018">
        <property type="protein sequence ID" value="ABX07018"/>
        <property type="gene ID" value="Haur_4386"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4386"/>
    <dbReference type="HOGENOM" id="CLU_2246250_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4440-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="104" mass="12147" checksum="A4D874FAA395C5CF" modified="2008-01-15" version="1">MSGMQLFLTALILAGNVLWWLRGVRLTEDWFFGQWLSQRWQVEIRRSERFKGKTWEIHPNDLSKISTGKRASFQIIQSVFPLISAIPTIFSIFLITWVAAMFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ16</accession>
    <name>A9AZ16_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4424"/>
    <dbReference type="EnsemblBacteria" id="ABX07056">
        <property type="protein sequence ID" value="ABX07056"/>
        <property type="gene ID" value="Haur_4424"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4424"/>
    <dbReference type="HOGENOM" id="CLU_1281747_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4479-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="215" mass="24645" checksum="DAD03D9D1293288F" modified="2008-01-15" version="1">MTAIQRWLMAALALSCLVLSFYSYTINHNLQVVQARQYGQIATTGESLWFSWYKCVEELSFAMSAADQNNQAYVLEYLSNAELYCQLSTQFIYNYDSALNWPIKPWWNLSLTSSGNGVGFVNLFIYYPSKINQIHSSIKEESLVSPANRARIQQLHDDIKIFAQQIPESMLQEGDIDKIHEALAGWCGMVNDVKAKETIILAEEQYRGVCRKEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ22</accession>
    <name>A9AZ22_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Core-binding (CB) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4430"/>
    <dbReference type="EnsemblBacteria" id="ABX07062">
        <property type="protein sequence ID" value="ABX07062"/>
        <property type="gene ID" value="Haur_4430"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4430"/>
    <dbReference type="HOGENOM" id="CLU_2219502_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4485-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="2">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="106" mass="11877" checksum="A295320FC8851639" modified="2008-01-15" version="1">MTMQELLVHERTLLGALDSFAGTLVRTRPQLAADYNEYLDDFAQRWIDSGYPNELDSISTYWVQAYLSSLSLAQREVAKAALHSFFDWAVSQGLIDQAPLSGGYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ60</accession>
    <name>A9AZ60_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_0958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0958"/>
    <dbReference type="EnsemblBacteria" id="ABX03606">
        <property type="protein sequence ID" value="ABX03606"/>
        <property type="gene ID" value="Haur_0958"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0958"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_6_0"/>
    <dbReference type="OMA" id="WRAAWMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-972-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="264"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="423" mass="45826" checksum="12413BE5FD034DAD" modified="2008-01-15" version="1">MAIDFKLSESIDTQRQMAQMVAEQMMRPVSRHFDEHEHDIPWDYINAMWPIMRQNPMFGAVDKPETATDPSKPKKPKTGNVRMVHLIEALSWGDAGMYLTTPGGALGGAAVAAAGTNDQKNRFLARFGESETPVWGSMAMTEPQAGSDTSAIRTTAVRDGDSWILNGEKIYCTGGRLSLEESQGLVVVWATVDPKLGRAGMKAFVVEAGTPGMQVTKLEHKMGIRASDTAAVVFTDCRIPFDNVLGNPEIPKAEATAASADAPKGFKGAMKTFDATRPAVAASALGIARAALELLREQLSLAGIPIRDDVPVNEMSAIERDVLELEAQHKAAWLLTLKAAWMMDSGEANTVEASACKVKAGEAATVITQKAVELLGPLGYTRELLAEKWMRDAKINDIFEGTGQINRLIIARRILGFSSRELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZA7</accession>
    <name>A9AZA7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1005"/>
    <dbReference type="EnsemblBacteria" id="ABX03653">
        <property type="protein sequence ID" value="ABX03653"/>
        <property type="gene ID" value="Haur_1005"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1005"/>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094875_1_1_0"/>
    <dbReference type="OMA" id="PYDYVEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1022-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00002">
        <property type="entry name" value="YbaK_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006181">
        <property type="entry name" value="EbsC_YbaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17161" checksum="F4C48543D1DE43DA" modified="2008-01-15" version="1">MGTRTRATDVMCRVTSDFELLSFEATEFTAEEAAEKLSLPLNMLFKTLLAKGEKKGYVLAVVPSDHRLSLKKLADALGDKRVEMAPIEELTRLTGYLKGGVSPLGTRRAMPVVLDFSAFQHARISLSAGQRGLQMLVAPSHLQQAAKALVADISDNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ0</accession>
    <name>A9AZQ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07104">
        <property type="protein sequence ID" value="ABX07104"/>
        <property type="gene ID" value="Haur_4472"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4472"/>
    <dbReference type="eggNOG" id="ENOG5032TNB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109759_0_0_0"/>
    <dbReference type="OMA" id="PTTGHER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4527-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="197" mass="22479" checksum="A07C1BA8F3451CD3" modified="2008-01-15" version="1">MKQNSPNYQLPKAVHQAGRPLFEQQCWCWGHDVRRCAGNLLLEYGATRSRVPAEQRGSSNYHFQLNCGARMGLWGWGLWYGDGYAPSLFLRRDKLQVGLIERAAPLCDVWSLSQIPAVRAPHNWAEWLRMTSLLGHCCTWIAAYEQWVIEQAGLTYRQACIADWQKPALPAHEMAERWQQLNDLIIASQENLSLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR2</accession>
    <name>A9AZR2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4484"/>
    <dbReference type="EnsemblBacteria" id="ABX07116">
        <property type="protein sequence ID" value="ABX07116"/>
        <property type="gene ID" value="Haur_4484"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4484"/>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_256190_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4539-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1372" mass="144111" checksum="DC2A83E53F6AEB34" modified="2008-01-15" version="1">MINRSSWQFRSQLLVSSGLVGLMVLLTTFLTTSSSAQTRECRMADALKICANTFVATDPTHFIARDDVTLAIGDAPPLISAGAVGANLGEFVFTADQSVLSGAVKFIGDNASLPLVASTYNANNTPKEVFEVDTTGLTITNDQSSADPIGVIANSTISLHFLDRSGVRSFYKTTDPSETEDLSFVFDLAAAEFRAELPINLNIAALNPSTSENPNLNIVVNLKYSQQGVLSGNVDNFTMSLAGMSVAVKEIALSTGSFEAGLVEVSRAANPDLPNLDPAKPNLVFSLQNLKYANRSFSIGGGSVPIPDWKFGGNFSMTDQTLSIGHDNATGTSTVSVNSTLIFGNVLNQPESATPREVTLTFSAVKVNGVFKPVFSATVAETTVAMGPLNFRLRGLSLIGDTVENFYGLKASAVDLLWSSDMGGQSAAGITGFKFGINKDGKLQFALGGATISTPNISSGVLEGSSIVGQFGVAQQTLNLTVTGNLSVKIPGNSGVGAGLVMVVRGGPNVAPIGSQNCAQSPCIKRFEASLTNFSVKIAGFSMALQNPRFLDDGGFAADSARLSMSDLMGNLTADVSGLSISGRGEVSVTGGGIELPPLKIAGTNFVGFRGFFSKDGAGYMFAGGATLSMPGFDPSGGSTISVDVSVKTLPTGVFNELDVVVAFESSPGIPLANSGAALTKMSGSFSLKSGSVTIGVGIEVSSVAQLAGIPLVSAEGTATLVVDPFKFSLTASMKVLIFEVASASVEIGHEAGFSGGKGLHAKFQFEAVIVRGGLELRVGTVTVRSCTPAGSTNCVDKQKLRFAGSARMSVGLRKGQFGKALPPKNITFGSVSFQMGEFEKSGGGTTVGMLGRVSCCFGIFKVSVFVDLSKPVGLNTGFVKLVNPKNYRLINSLQIAQSIEQGEPGYSQRIISRPVNPGKSGGALFAAIPEVTVPVVITSTASGYFGIHFSGTPSVEPVIRLILPDGTELNEGNVNDTTQTLIRDYTTVITEGNDLAFMLEAATPGTYSLIIEGPPSQYEVVAYQLNNPPIFDSATLACGGAATPGVTVTCNSAPTGSKVTVNWATRDTDDPNAKVSLVYASVITPTDPIDVGLSTVISDNIKLGTGQHVWDLSEIPSGQYKLALFADDGHNQPTVQQLDTLIVVNDQRAPKIPTNLQATPLPGQLLVKWTPNSEMDLGGYEIGFGEVNDPNEFLYSRNMGGKEMIFTATNQLDAKLWGLKDNQSIFYGIRAYDLSGNFSAWSPLVVGTPWSLSPHAWNPVPGGRGVTTTKIEAAFETPLSEASLTNAFQVRNASNQLVAGTPIYLYNLDKTEIIGFSFKPSATLVDGETYTVTIRGGANGIRSKDGRQMPADFSWKFEVESYQIYLPAVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY5</accession>
    <name>A9AZY5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1044"/>
    <dbReference type="EnsemblBacteria" id="ABX03692">
        <property type="protein sequence ID" value="ABX03692"/>
        <property type="gene ID" value="Haur_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1044"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_0"/>
    <dbReference type="OMA" id="WIQPEVA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1061-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="73"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36868" checksum="06D15AF46DE82386" modified="2008-01-15" version="1">MNIKPQKRSLLRRIGRWLAWLGLLIVGLLIGGWAFQRWASQRDRQQFLPAEQQIMLNGHAMRLICMGSGSPTIVLESGLGDGADVWGLVQPALAEQYRVCAYDRVGMGWSAAVANKADRASIAQTLHELLSQANVSAPYVLVGHSAGGLYVREYAQRYPEQVIGLVLVDSSHEQQRQRQPQLAEDPFAIMRQSMQACDALAPFGIIRLTKLFEQSQSTYAKLPQPAQASIAASQYQTSTCSAMDAALAAITQDLNQAQAPQSLKDLPLVVLTRGIADSTMPAEFEQTWDSLQQELAQLSSNSQHHIAETSGHYIHLDQPALVIEAVEWVISQQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H2</accession>
    <name>A9B0H2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4559"/>
    <dbReference type="EnsemblBacteria" id="ABX07190">
        <property type="protein sequence ID" value="ABX07190"/>
        <property type="gene ID" value="Haur_4559"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4559"/>
    <dbReference type="eggNOG" id="COG1794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055360_1_0_0"/>
    <dbReference type="OMA" id="AECLLMC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4614-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="25095" checksum="BC0B9FACDA4704FF" modified="2008-01-15" version="1">MKTIGLIGGMSWESSVSYYQVLNQTIKQRFGGLHSAKCVLYSVDFAEIAALQKADQWETAGEILAQAARNLVAAGAECIVLCTNTMHLVATAIEQAVEVPFIHIVDPTAAAIQQQQLTTIGLLGTRFTMEHDFYAGRLRQRYGLAVVTPEPEQRDEIHRIIFDELCLGKIDASSKTYYLAVINDLVAAGAQGIILGCTEIGLLINQADCDVPLFDTTLLHGQAAVAWSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0P1</accession>
    <name>A9B0P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07259">
        <property type="protein sequence ID" value="ABX07259"/>
        <property type="gene ID" value="Haur_4628"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4628"/>
    <dbReference type="eggNOG" id="ENOG502ZTWX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1966627_0_0_0"/>
    <dbReference type="OMA" id="DIWSTRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4685-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="14138" checksum="70BBE19C7A779254" modified="2008-01-15" version="1">MISSSVYMLLEQAIDTPEKLHCVMLFAQRTVNQGTATHIARQLGRDIWSIERALKELSEAGILSIAGEGKSSCYDYQPRSYVVNALELLVQTYNDPILRSEICDYVRELASYAPYRAHFHTVLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B102</accession>
    <name>A9B102_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M29 aminopeptidase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2642</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2642"/>
    <dbReference type="EnsemblBacteria" id="ABX05280">
        <property type="protein sequence ID" value="ABX05280"/>
        <property type="gene ID" value="Haur_2642"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2642"/>
    <dbReference type="eggNOG" id="COG2309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057697_0_0_0"/>
    <dbReference type="OMA" id="GRAYDAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2672-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="41495" checksum="9CE2CA7A4C33CD29" modified="2008-01-15" version="1">MFDQRWQQLAKIIVHHSLELQPNDLLRIQAEAIAKPLLYALYREALHAGALVIPKIVDPVFEEIMLKEGTPEQLQFVPSTLVHEIETMTTWCDIYSEINTKHFNQADQQRQLLRRKAFGPVQVLFDSRAAQNQLRWCDVLYPTEAFAQDAGMSLWDFEDLVVKSYLLDHPDPVTAWQTIHQQQQKVTHFLNSCRSIRIEGPDVDLSYRCEDRIWINCAGKRNLPDGEVFTAPIEDSVNGRLKISYPSIYQGNLVSGIQLVIEDGKVTQATAEQGQDFLHTMLDLDAGARYIGEVAFGLNPGITKPTGHTIFDEKMAGTMHLALGRAYPECGGKNESTLHWDLVCDLHQAEVYANNALCYKNGEFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B110</accession>
    <name>A9B110_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2650"/>
    <dbReference type="EnsemblBacteria" id="ABX05288">
        <property type="protein sequence ID" value="ABX05288"/>
        <property type="gene ID" value="Haur_2650"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2650"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048478_0_2_0"/>
    <dbReference type="OMA" id="HSPEHAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2680-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="22"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="37125" checksum="C6DB2E89387CBE92" modified="2008-01-15" version="1">MFEPITTDLYRVPIPVPLPLKYVNCYLLKADHGWVVIDTGMRYAQAEQTWQATFEQLGIAWSQIKQIIVTHYHPDHYGMAGWMAERSGASVWMSPIEIQSVQRAWYQPLPDAADHLADFFELHGMPNDLNRQIWQHTMDASQYVDPKPLLQTLDMTQPLQLGQRSWQLLHAPGHADGQLCLYDAADQLLIVADHVLADITPNISLWPEAKRDPLADYLASLNEFAALDVRLALAGHRKPIMAFRERCHEIAQHHDQRLDLMQQYASTGKTAFEVCEFAFGVTTLSAHQLRFAITETLAHLVYLEGQGRLQREQRARQIIFLDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B114</accession>
    <name>A9B114_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2654"/>
    <dbReference type="EnsemblBacteria" id="ABX05292">
        <property type="protein sequence ID" value="ABX05292"/>
        <property type="gene ID" value="Haur_2654"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2654"/>
    <dbReference type="eggNOG" id="COG3967">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_6_0"/>
    <dbReference type="OMA" id="WSMNLRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2684-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="241" mass="26506" checksum="699688C13C43B0FC" modified="2008-01-15" version="1">MQTTGHTVLITGGAAGIGRALALRFAQAGNHVIAVGRDAHKLAELKATQPAITTIQADLAQASERQRLAEQVSNISILINNAGVQYHGDLVEQQYAQVERDQEIAINLTAPIDLIQRFLPTLQQQPEAAIINVSSGLALVPKQQAPIYCATKAGIHIFTKALRWQLEQTRVRVFEIIPPLVDTAMTAGRGKGKISPEALVEEFWRGFSRDKYQLAIGKVKLLIQLQRFVPSVADRLMRYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B131</accession>
    <name>A9B131_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA/RNA non-specific endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2671"/>
    <dbReference type="EnsemblBacteria" id="ABX05309">
        <property type="protein sequence ID" value="ABX05309"/>
        <property type="gene ID" value="Haur_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2671"/>
    <dbReference type="eggNOG" id="COG1864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_581102_0_0_0"/>
    <dbReference type="OMA" id="NEMLLIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2701-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="Extracellular_endonuc_su_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="PTHR13966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LTD" evidence="7">
        <location>
            <begin position="291"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="470" mass="49632" checksum="280EE91511434D78" modified="2008-01-15" version="1">MKDRRLITLLALFVLGFVGASLVQPTQAKTVSSDNLVLGNPSGAVASSSYPTNYLIQRNQYALSYHRDNGIANWVSWHLDSGDIGSVSRSDFQTDTSLPSGWYRVATGDYSGSGYDRGHMTPSGDRTATTADNQATFYMTNIIPQAPDNNQGPWVDLETYARELVSAGNELYIISGGAGSRGTIASGKVRIPNSTWKIIVVLSQGSNDLSRVSNNTRVIAINMPNVQGIRDNDWRDYLTTVDALESLTGYNFLSNVSTNIQNVIEARVDGSTTPIPTAVPTSGTNPTATPVRTATPTPSTGCTSSRLFFSEYVEGSSNNKALELYNNTGASVSLSGYSIQLYANGSTSASSSVNLSGSVANGATYVIANASASSSVQNLANITSSVANFNGNDALVLTYNGTVVDSFGQVGNDPGSSGWGGTTTDRTLRRKATISAGDTNRSDSFTPSSTWDSYSLDTFSGLGNHSVSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B158</accession>
    <name>A9B158_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2698"/>
    <dbReference type="EnsemblBacteria" id="ABX05336">
        <property type="protein sequence ID" value="ABX05336"/>
        <property type="gene ID" value="Haur_2698"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2698"/>
    <dbReference type="eggNOG" id="COG1547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125317_2_0_0"/>
    <dbReference type="OMA" id="AGEYWHA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2729-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005500">
        <property type="entry name" value="DUF309"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023203">
        <property type="entry name" value="TTHA0068_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34796">
        <property type="entry name" value="PTHR34796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03745">
        <property type="entry name" value="DUF309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140663">
        <property type="entry name" value="SSF140663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13880" checksum="34374D717EEDAB12" modified="2008-01-15" version="1">MPIQQTSEFIQGFELFNAGHYWHAHEAWEVQWLQRNGNERDLLQGLIQTAAALVHWSRGNPKGLLLNWHKAAPKLQAALTWVDFLDLQHVIVTMQALVDDQAKHPPQLRFVSASDPLCNQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B162</accession>
    <name>A9B162_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin B12-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2702"/>
    <dbReference type="EnsemblBacteria" id="ABX05340">
        <property type="protein sequence ID" value="ABX05340"/>
        <property type="gene ID" value="Haur_2702"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2702"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045945_3_0_0"/>
    <dbReference type="OMA" id="IWEKRYN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2733-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="184"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="305" mass="33732" checksum="8AA90C68321FBA48" modified="2008-01-15" version="1">MSKITDRFTHFSQEPLYNTKAVVQRTGVAADTLRAWERRYGVPFPERTEGRQRAYSDRDIAIIDWLRQQTESGLTISQAVALLQTDSVIEQPTYDLAPLAELSNDCVQALLSFDVLKAEDILNKAFSVYPVETVCIEVIERVMVAIGDGWHAGKISISQEHAATAFMSLKLSNLIHQARTRSNRGVIVVATVPGEQHELGVMMVALFLMRRGWRVVYLGSNLPAAELLHTVQRLSPKLVALSATTKDNYSQAVQLLQELHKMPKPPIIGYGGAALSGTTQQTVLPGIFLGYNADQACDKIEELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F0</accession>
    <name>A9B1F0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX07337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX07337">
        <property type="protein sequence ID" value="ABX07337"/>
        <property type="gene ID" value="Haur_4706"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4706"/>
    <dbReference type="HOGENOM" id="CLU_2117647_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4763-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="114" mass="13210" checksum="4BC56C94BD196F85" modified="2008-01-15" version="1">MAYQPDIAVTMTFFGSTSPKVPVFFTKETRTSFYYPHDLLGFYCVFFSADDRMAFPGETIVGWISFLEPDQQQEKIHEGLTFEFRAGRPVICEGTVIEVINPRLWAENREQDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1J9</accession>
    <name>A9B1J9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1236"/>
    <dbReference type="EnsemblBacteria" id="ABX03884">
        <property type="protein sequence ID" value="ABX03884"/>
        <property type="gene ID" value="Haur_1236"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1236"/>
    <dbReference type="eggNOG" id="COG4134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045122_0_0_0"/>
    <dbReference type="OMA" id="PLWAYLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1258-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027020">
        <property type="entry name" value="YnjB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029172">
        <property type="entry name" value="UCP029172_ABC_sbc_YnjB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731789" evidence="1">
        <location>
            <begin position="31"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="429" mass="46525" checksum="E534B31288AC06F0" modified="2008-01-15" version="1">MQATARKRIWNLGLLIGLLSLIIASCGSNTATPTSAPSSTSLDLSNWTSIEQAANGQTVNWYMWGGSDSINRFVDEFYGKALKERYNITLNRVPVADTVDVVNQLLSEKEAGKTSGAVDLIWINGENFASLKQAKLLRGDWGQSLPNSQYVNWNNPAVNLDFGEPVESLESPWSSAQFQLIYDSAKLQASDLPRSYAALKEYACANPGKVSYIAPGPGAFQGTRFVKQALFEISGGAEQWLGAFNQQLWDQWSPKLWEYFNDLEGCLWREGSTYPKTENELHSLFANGEVDFSITQAIAGAGSLIKENLVPASARAFVFDDNMIGDFNYVAIPSTAPNPAAALVLANLILDPQLQAAQILPENGFGLGYGIDPTKVSDPALAAKLASAAQQLGDPATPASDLAKSLRSDIAAEYQSLIEQGWDANVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L5</accession>
    <name>A9B1L5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4401 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1252"/>
    <dbReference type="EnsemblBacteria" id="ABX03900">
        <property type="protein sequence ID" value="ABX03900"/>
        <property type="gene ID" value="Haur_1252"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1252"/>
    <dbReference type="eggNOG" id="COG4984">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064717_0_0_0"/>
    <dbReference type="OMA" id="GFIWYYS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1274-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025513">
        <property type="entry name" value="DUF4401"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14351">
        <property type="entry name" value="DUF4401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4401" evidence="2">
        <location>
            <begin position="33"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="353" mass="39195" checksum="4E47D6689377F2CC" modified="2008-01-15" version="1">MSTARYSLRQLFADLELEPPTFVLTAQPPSEDPWYMRIFAGIGAWFAAFMFLGFLAITNIITNEFGALVVGLGLCAVAIGINRTNQASTFLRQLALAISITGQALVLFGWTIIVESVIVAALGMIVLEIALFVAHRDFSQRLISTLGVITAIHVIAGDLNNWVESFNYMYLLLSVMIISFSLLMWFEAKIHEDQRWSSASPIAYGMLLFMAISSLLINFNWAEFFSRGSFFILPALVGIICLGTTIWMIINEFEYKLGFIELGCIAFGLLFIAFAGINTPAIIIALLIILLSYWRGYPVMFGFGCLALIGALSLYYYNLNISLLYKSIILFGTGMMLLAIRALVLKLNQKEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1U6</accession>
    <name>A9B1U6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chitinase</fullName>
            <ecNumber evidence="7">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2750"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05388">
        <property type="protein sequence ID" value="ABX05388"/>
        <property type="gene ID" value="Haur_2750"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2750"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_4_0"/>
    <dbReference type="OMA" id="IRAAYWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2781-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="147"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="521" mass="56345" checksum="9B254BF8222DFA3E" modified="2008-01-15" version="1">MNLIHRRFRFLAFILIPVLVMLMALSQQKVQAAAPAWDGNYHAYAIGARVSYAGGEYECIQPHTSLPNWNPVDVPALWRAVSPSNPTATSIPATATPRPATSTPLPPTATPRPGTATPTPNNPTATPRPATATPVLPTATTTPGGGKRIIGYFAEWGVYGRNYHVRNIKTSGSAAKLTHINYAFGNVVNSRCQLGDTYADYDRAYSAAESVDGVADTWDTGVLRGSFGQLRKLKAEFPHLKVLISLGGWTWSAGFSDAALPANRAAFVKSCVDLFIKDPRWAGVFDGIDIDWEYPAACGNTCNYRPEDTQNFTALLSEFRSQLNAVRPGLLLTIAAPADPAKIAKIQVGQIHQYLDFINIMTYDLHGAWEANTNFQSNLYSIAGDPGPVYSVDIAVNAWLNGGTPADKVVVGVPFYGRGWKDVPSTNNGLFQPGSAAPATYEAGIEDYKVLKTKGLTRYSNSAAGAAWLYGNGQFWTYDDPAIMKVKTDYVKAKGLGGTMFWELSGDTTNGELINALYQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B208</accession>
    <name>A9B208_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4727"/>
    <dbReference type="EnsemblBacteria" id="ABX07358">
        <property type="protein sequence ID" value="ABX07358"/>
        <property type="gene ID" value="Haur_4727"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4727"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_3_0_0"/>
    <dbReference type="OMA" id="IKSPIIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4785-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="16587" checksum="455D54E9D8E8A3B4" modified="2008-01-15" version="1">MSEQTPEQNLLTEDVRELLRLITQTDITELSLERGDAKIHVKRTPYAVAAPVVVTSGVAATPVAANVAETPAAPIGQPITSPMVGTFYASPSPKDPPYVKVGDEVHPGDVVGIVEAMKMMNEIESEIHGRVAAIHVENNQPVEYGQVLISIVPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B290</accession>
    <name>A9B290_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4809"/>
    <dbReference type="EnsemblBacteria" id="ABX07440">
        <property type="protein sequence ID" value="ABX07440"/>
        <property type="gene ID" value="Haur_4809"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4809"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_1_4_0"/>
    <dbReference type="OMA" id="VQCEYFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4868-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="27786" checksum="2F875E927D42D487" modified="2008-01-15" version="1">MKPRIIAVANQKGGVGKTTSTVNIAAELVARGQRVLVIDLDPQGNATTSLGINKKALKATVYDVLLGNAPTEIVLTATGREQLQLLPATVELAGAEVELVDEHRREHRLRDALAPIASTFDTIMIDCPPSLGLLTLNALCAAHGVIIPLQCEYLALEGLAQLKNTIDLVRTSLNPALTILGVVMTMYDGRTNLAQQVVSEVRQYFPQRIFNTLVPRSIRLSEAPSHGQTIREYDPASKGAMAYAMLVDELSRRLEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B3</accession>
    <name>A9B2B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1310"/>
    <dbReference type="EnsemblBacteria" id="ABX03958">
        <property type="protein sequence ID" value="ABX03958"/>
        <property type="gene ID" value="Haur_1310"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1310"/>
    <dbReference type="eggNOG" id="COG1739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083552_1_1_0"/>
    <dbReference type="OMA" id="VTVDHQR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1332-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015796">
        <property type="entry name" value="Impact_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00257">
        <property type="entry name" value="IMPACT_YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="142"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="22406" checksum="A10929F4B1D731C6" modified="2008-01-15" version="1">MTPTRYQIPAAEHEFEQDIKHSRFIATVVHAPSLVEAKQAIATIAARYPDATHNCWAFQIGLGPQAEIGSSDDGEPAGTAGRPMLQVLQGSGIGDIAAVVTRYFGGIKLGSGGLVRAYSGTLQKALNDLPTKEQVIRRTGMVTINYNQYELLRRLLNTFDPVIESEDFASDITLMLALPQDRWQECAAAIRELTYAESELIALDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E1</accession>
    <name>A9B2E1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1341"/>
    <dbReference type="EnsemblBacteria" id="ABX03986">
        <property type="protein sequence ID" value="ABX03986"/>
        <property type="gene ID" value="Haur_1341"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1341"/>
    <dbReference type="HOGENOM" id="CLU_596866_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1362-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="457" mass="48590" checksum="9C6DAD7CAF987A83" modified="2008-01-15" version="1">MTTMQLLRNGSVVIDFMPSVNPTEGTTCYWLVDGSWQPQVPQRDRRLISNGEQLMPSVQSFAVNIFGGTNEDQAWAAYHALMVLLDDAERFYEEGYSSAVVWRTKPSDNTVHSDMLVMGRAGDTPMVGTSPTLIQDNDVWWILNVPVTFLCRPLRCATSSVSSSTSASANIATIHQPTFSGSAAPMESPTNLTLNVAAATNGATINGLIAVAPRGKMVKSAAWLFAPSPSVGGWSRQIQASGVYASDNLVCFYNFPSVTPSYSPNGVLTDIGAMNCRSVIQWAMLRTTAPFLITPVVRSNGALIEGRATLVDSATPIIVPLGQTSSPYLISGHQLKLTNLTNAGAIYINAILTIAADAGGWSVIPFASLPLPSTATTIIVDARYLSNPDASLTWTNAGVTQAVPTDSNPLVLTKDLQLDVNIFAVNGNSWSATAEGSASARTMTVQASRLNSAIIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H4</accession>
    <name>A9B2H4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1374"/>
    <dbReference type="EnsemblBacteria" id="ABX04019">
        <property type="protein sequence ID" value="ABX04019"/>
        <property type="gene ID" value="Haur_1374"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1374"/>
    <dbReference type="HOGENOM" id="CLU_1822676_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1395-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="14973" checksum="E5A85AF356C24EF6" modified="2008-01-15" version="1">MAKKGVAQYQSFAKRFRVRIDGATRDLLNEAALAGEGHAKQNMVANNSIDTGFALNSIHAVLVDGQGVDAATTDLPDKHGDVVQRTSAGLPAMGDNTSAVGCAATYAIYIELRAPFLFPALDQVKADFGSIVQVVRRKRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K3</accession>
    <name>A9B2K3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2816</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2816"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05454">
        <property type="protein sequence ID" value="ABX05454"/>
        <property type="gene ID" value="Haur_2816"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2816"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021574_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2847-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734505" evidence="2">
        <location>
            <begin position="38"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="24"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="166"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="320"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="4">
        <location>
            <begin position="468"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="752" mass="82078" checksum="B6A6B67B87BDE5C0" modified="2008-01-15" version="1">MFSNVRFSSRGASRLALLACLVLSPMLLLGQPQSTFAATNLALGKTAVASTSENADFGAALALDGNVNTRWSSTFADGQWLRVDLGSVQSFNNVVLRWEAAYASSYRIQTSNDANTWTTIQTITNSDGNVDDLSISGTGRYVRVESITRATPYGISLFEFEVYGNAGSSNIALNKTTSASSSENAATTANFAVDGNVNTRWSSTFADGQWLRVDFGSVQSFNRVVLRWEAAYATSYRVQTSNDANSWTTIQTVTNSDGNVDDLSISGSGRYVRIESVTRATQYGISLFELEVYSGSIQPTVQPTTQPTTQPTVQPTAQPTTIPGNCTTSTNIALNKPAYAWFYESKTSSPAQAVDGNATTTRWSHLWYPSGPANAWLYVDLGSTNATINRVRILWESAYAADYQIQVSNDRSNWSNIRSVVGNTQTTNDYNLTPITGRYLRINMTKKGTEYGYSIWELEVYGCNAGNPSYDPAPTPLTGNFSRVWVENFDGTSLNMNNWAYDNDVHVNGEQQQYTSNNVAVSGGTLKITARKETANGYPFTSGRIFGLGRQSFLYGKMVARMKMPVGEGYWPAFWMMGANINEVGWPGNGELDIMENIGYGNWTSGALHGPGYWGAGSAGGLVNLPAGQTTGAWHTYAVEWDPTYIKWFVDDREILSFTRAQIIADYGQWTYNNPKFFILNLALGGEYPAGYNGCTGNPLPAGCAYFGVKQSTVDSIVAGNGLLEVDYVEVWQKPAATTQGAQYLPLAQQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L5</accession>
    <name>A9B2L5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-amylase</fullName>
            <ecNumber evidence="5">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-maltose = alpha,alpha-trehalose</text>
            <dbReference type="Rhea" id="RHEA:15145"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="EC" id="5.4.99.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family. TreS subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2828"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05466">
        <property type="protein sequence ID" value="ABX05466"/>
        <property type="gene ID" value="Haur_2828"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2828"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_1_0"/>
    <dbReference type="OMA" id="FYQIHPE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2859-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047471">
        <property type="term" value="F:maltose alpha-D-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012810">
        <property type="entry name" value="TreS/a-amylase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02456">
        <property type="entry name" value="treS_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="13"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="548" mass="64324" checksum="886F3C6F7E3D578C" modified="2008-01-15" version="1">MQNDWYKDAIFYELHVRAFQDSNGDGNGDFRGLISRLDYLQSLGVDCLWLLPFYPSPGKDDGYDVADYCNVHPSYGTMEDVVTFFEAAHSRGLRVMIDLVVNHTSDQHPWFQAARQPDSPYRDYYVWSDTNQRYRDARIIFTDTERSNWAWDEVSESYYWHRFFSHQPDLNYENPAVLEEMYNIMRFWLDRGVDGFRVDAVPYLIEREGTNCENLPETHVILRKMREFVDQHYPHCVLLAEANQWPDDVRHYFGNDDEFHMAFNFPVMPRMFMAVRKEDSTPIIDIVRQTPKIPENCQWATFLRNHDELTLEMVTDEERDYMYREYAADPRMKINIGIRRRLAPLMDNARRRMELMNSMLLSLPGSPIIYYGDEIGMGDNIYLGDRNGVRTPMQWNGDRNAGFSAADFARLYSPVIIDPVYGYQAINVEAQERVQSSLLNWMKRLIRVRKRYSVFGRGDIQILETQNRKVLAYLRSYADQTVLIVNNLSRFIQPVELDLAEFAGMRLVELIGETPFPAIATTPYFLSLAPHGFIWFRIEGVRLALDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N2</accession>
    <name>A9B2N2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2845"/>
    <dbReference type="EnsemblBacteria" id="ABX05483">
        <property type="protein sequence ID" value="ABX05483"/>
        <property type="gene ID" value="Haur_2845"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2845"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="GHDHVHP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2876-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="32061" checksum="77569E4332121200" modified="2008-01-15" version="1">MQPIIELRDVGLRYADRLVLDQINIHLHHGQFAALVGPSGAGKTSLLRLILGLHAPSHGQILTHGKHPVDNQVPTIAYVPQLETVDWNFPVTVEQVVAMGLVRQGNPWPWLRKHQRQAVQAVLTQLEIEHLAQQHIRNLSGGQQQRVFLARALVAKPAMLVLDEPTTGIDPRVAETILHLLADLNQQGMTILMTTHDLNSAANHVPWIICLNQTIIAQGTPEAVFTPIVLEQTYHSEMVVVHHEGMLLIQQRPHGHSYRDLIPNPVIGEVLNPAMENPIEPAFRTAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y7</accession>
    <name>A9B2Y7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3414"/>
    <dbReference type="EnsemblBacteria" id="ABX06050">
        <property type="protein sequence ID" value="ABX06050"/>
        <property type="gene ID" value="Haur_3414"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3414"/>
    <dbReference type="eggNOG" id="COG2307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071567_1_0_0"/>
    <dbReference type="OMA" id="FWIGRYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3451-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007296">
        <property type="entry name" value="DUF403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04168">
        <property type="entry name" value="Alpha-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-E" evidence="1">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="35733" checksum="23E153CF869EFBA6" modified="2008-01-15" version="1">MLSRVADSLYWIGRYLERTEHTARLLDVNLSLMLDQTPAAAERRWERMQTYLAWNYEGIPQTYALVQALTFDVSNASSLVSGIGAARENARQVREQISSEMWEQLNRVYLQVKRTTMDQMWQEPHEFLHNVLKEGIHLFQGITTATLSHGECWHWLRLGQFMERAMATAILLDVHFAETGGTPDDQTNYLDWVGLLKSCTSFEAYCNVYTADIRPERIAEFLLLNAESPRSVRFAADQVAASIQAIASNTLGRRGDRVKRLAGRLQASLDYGQVDEIMADGLSGYLATIQQQCQQIHTNVYQTFISYPVETALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B316</accession>
    <name>A9B316_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sua5/YciO/YrdC/YwlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4849"/>
    <dbReference type="EnsemblBacteria" id="ABX07479">
        <property type="protein sequence ID" value="ABX07479"/>
        <property type="gene ID" value="Haur_4849"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4849"/>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_3_1_0"/>
    <dbReference type="OMA" id="LVDAFWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4909-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="21656" checksum="3FAF45EB1BA42567" modified="2008-01-15" version="1">MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVALPMLLADLDDLSKVARDIPDLAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVPNHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLAGRVPLVLDGGFAMGEQPSTIVDLSGEQPTILRQGVISAAQLSPWLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B368</accession>
    <name>A9B368_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4901"/>
    <dbReference type="EnsemblBacteria" id="ABX07531">
        <property type="protein sequence ID" value="ABX07531"/>
        <property type="gene ID" value="Haur_4901"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4901"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024570_0_0_0"/>
    <dbReference type="OMA" id="RYFRATD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4962-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01467">
        <property type="entry name" value="vWA_BatA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011933">
        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033881">
        <property type="entry name" value="vWA_BatA_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02226">
        <property type="entry name" value="two_anch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="89"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="36915" checksum="0086B9D77CDCB181" modified="2008-01-15" version="1">MTFAYPLLFWLLPIVPIVWWSMYRRSRGEVVTMRFSDLGMLRGVKPSWRIRMRPVLISLRAAAVGLLVVVLTRPQYAQSSERVVREGIDIQLALDISLSMKAGDFDPKDRITVAKEVIAEFVKGRKDDRIGLVVFSGHAFTQVPLTLDYDFLQNLLGQVQTVRRPDGTAIGLALAHSVNGLRNSTTKSKVVILLTDGSNNRGDIEPAQAAEIARALDVRVYTILVGKPGNGEYPVHDPWRDETYLIPAPTAEDEVALRDIAEQTGGIFFRAGDEQGLRDVYDTIDKMERSQVASEKLVRYTEAWQPWAAGALLLLMIEILLRNTILRSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B396</accession>
    <name>A9B396_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1415"/>
    <dbReference type="EnsemblBacteria" id="ABX04059">
        <property type="protein sequence ID" value="ABX04059"/>
        <property type="gene ID" value="Haur_1415"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1415"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_0_0"/>
    <dbReference type="OMA" id="DFRWAFV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1437-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="475" mass="49998" checksum="08ADE3F58699D7AA" modified="2008-01-15" version="1">MKRIVIDQKIAVCVVFVAALFMSIMDGTIINVALATIQQDFGASSSAINAIVVIYLICIAVVIPASGWLGDRWNTKWVFLTSLGLFTLASLACGLAQNIEQLMLTRAAQGIAAGALMPVGTTMLFRTFPPHQRIQVSRVLIIPTVIAPAVGPVLGGFLVDHLSWHWVFFVNGPIGLAALIFGVIWLQAPAQEEVGAFDWLGFILAGAGFAALLYTLTEGASKGWGSPIILVSAAIGVGALAALVVVELAKAKPMLDLRLFSIRLFRVSNLVAIFGSAAFTGILFLMPQFLQNVVGASALESGLTTSPEAIGVVLSSQIVARLYPKVGPRRLTFGGVLGVAVMMGLMSTIDAETNLWLVRALMFGTGVGMAYLFLPIEAAVFAQIPHASTGQASAIFSMQQQLGSALGVAILGSVLALNHSGTTVNQNAQSYQYAFLAAAILAFVSACVALFIRDRDAAATMAQHGEHSELSHSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C2</accession>
    <name>A9B3C2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1441"/>
    <dbReference type="EnsemblBacteria" id="ABX04085">
        <property type="protein sequence ID" value="ABX04085"/>
        <property type="gene ID" value="Haur_1441"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1441"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_232511_0_0_0"/>
    <dbReference type="OMA" id="NDGEYWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1463-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734531" evidence="4">
        <location>
            <begin position="31"/>
            <end position="2138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2138" mass="236559" checksum="1F7ECFC158E7F939" modified="2008-01-15" version="1">MILPNHRWKRLSMLLLACSLAQMLVPTTNAQQTAIAPQRQELPLSKAVDYALPKQQAVQLANTKALAAPGLTFELDLPNQVSIGQNVPFTLTLINRSTTEGQNIVVSLPVPAGTQALKNPNLVDQTHWQWQIKRLAPQSQQALTGSVRITSRPEHGALLFNPQANANNLPQPATLSAGALIAPQTSAKQAEIWQAQGQTIHSNDQRVSLVLPASATSANFSYSPYQSTANRQKALGYSEFVPERRGFSSFEIQAAQKSFAPVELQFHYSPEELQVLGLQEQTLRLFTYDQTSQSWQSIATTIDSINHVAKATITNDGAFNLSDGSSPSTAYLPTLQGFQGGGFTGAASYSVPIEVPAGAAGHKPAVNLSYSSAASDGSNGARPLWQASSVGKGWDLGIGGSIGRNTSAGSSDHQWDSFSLVFDGQSSDMVRGQPLDGNYTNLAESNWTWHATDETFVKLRKSASSDTWTAWTKNGTRYEFNQALRWGTNTPSNRFETYKWLLTKVVDPSGNAIVYQYYVDTIQAAEPIHPTWFLQNVFWGYDGATPGTGTPRYALSFDMSPRWSAPTENVDLNWEYTTSRVMGKAGTPHEAYRIDKIKVLSMPPGQTSYQLMRAYKLNYAAFANSLTTDVSNGQRVLTLANVQRLGKNNEALPAISFNYGMSQGNALEPTPGWNRLTQVDNGQGGLLTINYEHVWSQGVTDYAKYYQNYYRVANVVQADTSNLAYSRAYLTTYSYAYPALNDYGHSLAVVYAQYPESGNGDSRFALAHAEKSEFRGHAQVSERVYDGNTTAAPLLRTTETWFHQGNGGSAATPCSPAIITPASGNQYVNVSDSCYIAMRDSESWKGKVIAQETWFNGSRLSRTANSYTRVALPFYGNDGNATHASQSNNYKRAGLWRAFNYTAAITESTYEAGTTNARSLTTNFTYEPTYGNLTEKRVADDTGTVLRKELAWYATRDDANSYIVDRPWQTATTDGAGRYMALSANFYDGATNTNLLGTRGLLTRQSHYFNVPLQTDLTGTTLYGSDAVYGYDQYGNRTSQASYNADYSTRINTNGVVSYGVPGKGTAARTSTIEYDNTYHAFPIRETNPLNQSQQAEYDYQLGTVTKVFDLNGNATSATYDSFGRMTNLIKPGDSSSFPTAHIDYYDSYRPILYLVSLREDAGQSYFRPILHFYNGFGQEIQTKAESIDGSQHIVNDTSFDGLGRATSQSEPRYVSDTTNFWGYVPASNPLYQATTTSFDGLNRPLVITSPGNRTVEHHYGVTTSFLYDDVIDQNRHRTQYRYDVFGRLREVNEISGNCATGYWANYACGGSFTTNWSVATNTRYGYDALDRLITVIDAQNNTTSMRYDSLGRKMRIQDPDMGQYNYSYDAASNLNGQTNAKGQTVSFNYDALNRLTSQVFPDGSHNDYFYDVVGQQTAGYNYGKGHRTSMQSVLANGTIQTFQRWEYDARGREIFSGHNTDLTKAHHILTSYDSADRVKTRRYQPIDETVTYNYDAAWNEYSLCTSLGGCYVTGASYDALNQPTRVNYGNGSYNQYRYDDSTRLLEALEIFSAQGTNLYARNYWYDNVGNINGIGTWDNGSNNQTRQIQYFNYDDQNRLTRAWTTGDSAGAYDQSMSYDSIGNLLSKAGAAYTYPAAGSARPHAATTIGSKNYNYDANGNLSTTYTGTSTNGSGNRYSWDYANRLVQVESYVRAPISGGGSDCDDGNERIPDASNPEAIPPITCPHRSASPNQPTVDSYTVQEQYVYDADGKRSARIANGQTIIYFEGAWEDTLGVNARKLYTFNGSIVAQRDSDNTMSYLHGDQLGSVSIVTNASGGLKHKQEFDPWGNIREGGASSTKLNYTGQYRDDTGLIFMNARYYDPKIGRFISADTVVPGSPSGSMNGSGLRSLTTDFTDPAFTMSLNQEQRSTPWFTLSQAQQQDIGTPWGPANPQSLNRYSYVQNNPLTYTDPTGHARTVIRTAIEANRALTTLKAWLRDRNIGFEVKGAEIAGTTETMGINLLVDIDMLVLQLGTDMANIIRGYIDALNTMVTNPELFPDGIYLDYDVTRNGKWITTTMGWGFCDNADCSMTGDPVSQASSTYRHYTLFEQYLTAIDPTLLSQGFYLHNQRNMYIADNMSTVFFGIRKGQQSKYNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3H8</accession>
    <name>A9B3H8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2912"/>
    <dbReference type="CAZy" id="GH77">
        <property type="family name" value="Glycoside Hydrolase Family 77"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05550">
        <property type="protein sequence ID" value="ABX05550"/>
        <property type="gene ID" value="Haur_2912"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2912"/>
    <dbReference type="eggNOG" id="COG1640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014132_1_0_0"/>
    <dbReference type="OMA" id="TGQLWGT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2943-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="519" mass="58246" checksum="8A26F96A7E4E9AB7" modified="2008-01-15" version="1">MTFERAAGILLHPTSLHGRYGIGDLGSEAYQFVDWLQAAGARLWQILPLGPTGYGDSPYQCFSAFAGNHMLISPDYLARINLLAEWDLEQLTHLPAEAVDFGAVIPAKLQLLRTAFENFKAQADDRGFRAFCVAEQAWLDDYALFMACKAAHGGASWTTWDQAIALHEPAAISEWGNKLADDVQFHKFLQWAFFSQWDALKHYANERDIKIVGDIPIFVAHDSADVWANRSLFLLHPDGNPVDIAGVPPDYFSATGQRWGNPLYRWDVMAQDGYQWWQQRISASLRTVDIVRVDHFRGFAGYWAVPASEETAVNGEWRRGPGADFFQAISHAFGSLPLIAEDLGMITPDVYQLRDQFALPGMRILQFAFTSGAFQSNFLPHTYVQNTVAYTGSHDNDTSRGWYTSAGPEEQHRARTYLYCGEDAIVWTMIRTLYASVADTVIIPMQDALDLGSEARMNRPGYTGGNWAWRIKPDQLSYDLARSLYGLAEVYGRLAQPAISNELDPNAPPYFDLQETSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3I4</accession>
    <name>A9B3I4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase/Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2918"/>
    <dbReference type="EnsemblBacteria" id="ABX05556">
        <property type="protein sequence ID" value="ABX05556"/>
        <property type="gene ID" value="Haur_2918"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2918"/>
    <dbReference type="eggNOG" id="COG0400">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049413_5_3_0"/>
    <dbReference type="OMA" id="GRQWYGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2949-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="24446" checksum="B0153830645FC2EA" modified="2008-01-15" version="1">MSQISLTHEVVKPRQTSAEAKAPLLVMLHGVGANEHDLLPLAQYLDPRLCVVSARAPHRYQFGGFSWFDIHWHAKGFNIDTNQAQQSWETVQRFLGEACSAYDCDPKQIYLGGFSQGAIMSLGATLTKPELIAGTILMSGRWMPEVGPQTDREHIANKPIVAVHGVYDEVIPIQYGRAIRDFLQTLPVQLEYHEFAMGHEINLDSLQVVVKWLKQQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U0</accession>
    <name>A9B3U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3440"/>
    <dbReference type="EnsemblBacteria" id="ABX06076">
        <property type="protein sequence ID" value="ABX06076"/>
        <property type="gene ID" value="Haur_3440"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3440"/>
    <dbReference type="eggNOG" id="ENOG5034846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2023531_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3477-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="13258" checksum="6047400CDC65F4CB" modified="2008-01-15" version="1">MSDAPEMLPDEQPDAAPVFDKAAARARYRAMMRSWPMRLMFAMTGVVIVATWVFAFAAAYGPDVKELPNHDLSVAVADCKTCHNAGLPTAPSFNHSFAPTCGFCHVQSMPATLPLTSTSRLR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B419</accession>
    <name>RL16_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplP</name>
        <name type="ordered locus">Haur_4922</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B419"/>
    <dbReference type="SMR" id="A9B419"/>
    <dbReference type="STRING" id="316274.Haur_4922"/>
    <dbReference type="EnsemblBacteria" id="ABX07552">
        <property type="protein sequence ID" value="ABX07552"/>
        <property type="gene ID" value="Haur_4922"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4922"/>
    <dbReference type="eggNOG" id="COG0197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078858_2_1_0"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000142983" description="50S ribosomal protein L16">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <sequence length="145" mass="16228" checksum="A8C266680136183F" modified="2008-01-15" version="1">MLMPKQMKYRRPHRPRNIKGIAQRGATVAFGDFGLVSLEAGWITSRQIESARRTITNYVKRGGKVWIRIFPDRPITQKPAETRMGSGKGSVEYYVAVIKPGRVLFELNGVPEDVAQEALRRAAQKLPVKCKFVTKASQEVGSNEG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B424</accession>
    <name>RS14Z_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsZ</name>
        <name evidence="1" type="synonym">rpsN</name>
        <name type="ordered locus">Haur_4927</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B424"/>
    <dbReference type="SMR" id="A9B424"/>
    <dbReference type="STRING" id="316274.Haur_4927"/>
    <dbReference type="EnsemblBacteria" id="ABX07557">
        <property type="protein sequence ID" value="ABX07557"/>
        <property type="gene ID" value="Haur_4927"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4927"/>
    <dbReference type="eggNOG" id="COG0199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_3_0_0"/>
    <dbReference type="OMA" id="RAYTRCN"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_B">
        <property type="entry name" value="Ribosomal_S14_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023053">
        <property type="entry name" value="Ribosomal_S14_Z"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000143909" description="30S ribosomal protein S14 type Z">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <sequence length="61" mass="6985" checksum="5357BF68B239BF63" modified="2008-01-15" version="1">MAKKSMIVKANRAPKFSTQGYNRCKRCGRPRAYMRKFGICRICFRELASQGLIPGVTKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H2</accession>
    <name>A9B4H2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1493"/>
    <dbReference type="EnsemblBacteria" id="ABX04137">
        <property type="protein sequence ID" value="ABX04137"/>
        <property type="gene ID" value="Haur_1493"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1493"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_0"/>
    <dbReference type="OMA" id="FPQWGAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1515-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="24913" checksum="84E14D213043DBFB" modified="2008-01-15" version="1">MSKPLAGKVALVTGGSRGIGAASAVALAEQGADVAISYVASASKAEAVVEQLQALGVKAVAFQADQADSDQVAALVNKVVSHFGKLDILVNNAGVIQLAPLNDANADLEAVEHMFAVNVKGVASAVRAATPLLQDGGRIISIGSVSADTAPIPGFGDYSATKAAVAGYTRAWANELGRRGITVNNIQPGPIDTDMGPGDGPMLDMITQAIALKRLGKAEEVGATVAFLASPGAAFITGATINVDGGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N9</accession>
    <name>A9B4N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD40 domain protein beta propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1561"/>
    <dbReference type="EnsemblBacteria" id="ABX04204">
        <property type="protein sequence ID" value="ABX04204"/>
        <property type="gene ID" value="Haur_1561"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1561"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_836525_0_0_0"/>
    <dbReference type="OMA" id="WAFYPSF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1585-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734552" evidence="1">
        <location>
            <begin position="23"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="2">
        <location>
            <begin position="80"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="41410" checksum="55A16B9F6426D008" modified="2008-01-15" version="1">MRRSFYLLILLCLLAACSEAGSALPTMQPLPTNQAQPAVDETQATQIVVENQSNVPGKLLFVRVENGSGDIWVHEGTEARRITTSHKKYQPSWSPDGSKIAYIQREESFADIWVMNANGSNKQQVTNNEPTNIAARSEDHIQTLRWAFYPRWSPDGQFLSYVSQAQTPRDVGGGYQEYPLSLYIYGTRRIGTGQFPEASFQRFVQADTDLSHPTWSDDGTMIVYSQAERCFGCEAAEIQLGYAVLDLPGGNDEYGVLQGPSEDTFKGAIDPSFSPDGKWLTFTKSENGYSDVFIVPAPDTNGKVRSAPIKLTSTGRSRQATWSPDGTKLAFFTISDQVTLSIADLTIEGSTPSLSQPVDIRRDLFDVDSGMSWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P9</accession>
    <name>A9B4P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1571"/>
    <dbReference type="EnsemblBacteria" id="ABX04214">
        <property type="protein sequence ID" value="ABX04214"/>
        <property type="gene ID" value="Haur_1571"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1571"/>
    <dbReference type="HOGENOM" id="CLU_2329894_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1595-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10789" checksum="859608A718E5D59F" modified="2008-01-15" version="1">MDATQAIILCAGLQKSYAYEDSKFMFDIAGRPAFSYTMESILEVFPESAVTIITSQRFQDFNAFINQAYPTATVAFDDNPGSGTALSLKKATPFKKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B589</accession>
    <name>A9B589_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde ferredoxin oxidoreductase</fullName>
            <ecNumber evidence="9">1.2.7.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.5" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3590"/>
    <dbReference type="EnsemblBacteria" id="ABX06226">
        <property type="protein sequence ID" value="ABX06226"/>
        <property type="gene ID" value="Haur_3590"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3590"/>
    <dbReference type="eggNOG" id="COG2414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020364_1_0_0"/>
    <dbReference type="OMA" id="AHHKDAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3629-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033726">
        <property type="term" value="F:aldehyde ferredoxin oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="601" mass="64999" checksum="717DD7C0ED17DB1F" modified="2008-01-15" version="1">MAFIGRALRINLDTASTSTFDIPSPIRELYLGGRGLTAGLMYHFVPPDTAVRSPDNPLLLAPGVLAGTPAYATGGFVATTRSPLTGNLIHSWAVGDWGAALKRAGFDAVWVVGQATAWLYAVIDNGQAELYPANHLNGLDTQQINDALMAEHGADARVLTLGQAGEKMLPYAALVAEGRYLAEPAGTGMVMALKRLKAIVVRGTRMVKPADTANFLSSFKPITERIDRDPLATAIRDYGSSYYVDLAANHGAITGRNGQDPEPSVMPTTGDYAGEIYDRGCPRCPLPCYHDFATTNQPRPEIEAIVGFGARCGLQSPAAIIEANQRCLRYGLDPNATANAIAFLMECRQRELTRQYDLQWGDEAAILAAIDAIATKQGIGGLLSLGVYEMSQVFYGSEQFAPLANNLTISPLDPRAAQGWALHLATSSIGGDARGAMPWYEWLDTIPQWLKGNDDHQPNVVNGKPERLIWHERFVAGLDSAGICRRLAALAYQITPKELATILSADIGKSVSPTDLAKVGERIITVERLLALQWGHSDDLSTRWQQQPLTSGIAANQIPTLDTLLTKYYALHGWDSDGIPTNARLAELSIPEPDSRPWVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5J5</accession>
    <name>A9B5J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0168"/>
    <dbReference type="EnsemblBacteria" id="ABX02820">
        <property type="protein sequence ID" value="ABX02820"/>
        <property type="gene ID" value="Haur_0168"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0168"/>
    <dbReference type="HOGENOM" id="CLU_1127854_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-171-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732482" evidence="1">
        <location>
            <begin position="25"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="28067" checksum="F5A6D9A11D338E2E" modified="2008-01-15" version="1">MIKPFRWLSVGVVCGILIGCATTVQPTATPEPTTVPTAINNPQEAWQQWPTVLTDSFRDNRHKWMVGPLQSGDLTGEFAIGPDLYQMEMDLNEISIFPSLMPEYRVDREKGFYVSVEAKSMVKLNSSYGLVFLSQRKNNAKIVIDINEYYFEITGNYYRLLYYEQNNWNEIIASTNLPKKSEHGFDRLGVLVQGETVTLLFNDTYLTDIEVDDLFKSGLFGLVCGAYQPKVSQICEFDNLEVRMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5R7</accession>
    <name>A9B5R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1657"/>
    <dbReference type="ESTHER" id="hera2-a9b5r7">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04300">
        <property type="protein sequence ID" value="ABX04300"/>
        <property type="gene ID" value="Haur_1657"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1657"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1681-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="30"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="290" mass="33307" checksum="F614CA18924D133B" modified="2008-01-15" version="1">MTAYTIEHQLDNGIERIIYTPQEQRFQTPILMGHGMWHGAWCWQPWQALLAEWGWQSIAFSQPGHGQSPAQRANRWNTLGYYYRTLKAEIERLPIKPIYMGHSMGGALGQWHLAKGGDDLPAMVLVAPWLSHSMRPVFANAQKLDPWGTLLCWLSLSATPTVRTPKRAAFWFLSEDATIKPKQLHSQLAPESALVLLQYRWPLWRPAKQVKTPLLWLAAEQDRCIPEQYSRPSAAHYNAEYWVIPKANHDLMFEASYRETAELIHNWLQSVVTGTQHDQHSSLQFQSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T2</accession>
    <name>A9B5T2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1672"/>
    <dbReference type="EnsemblBacteria" id="ABX04315">
        <property type="protein sequence ID" value="ABX04315"/>
        <property type="gene ID" value="Haur_1672"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1672"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_0_2_0"/>
    <dbReference type="OMA" id="MQLLGAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1696-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="38970" checksum="92A74339A911FD29" modified="2008-01-15" version="1">MERRTVLITGAAGRWGRRLARQLAKFPIVRVIGLDITPPERPIDGVEYIQADLRNPLLVELLRTEKVEGILHMVFTSGLSGGRGLLSPEDAFQTNVMGTMEVLAAANAADVKQVVIKSTTMVYGAHVDNPLYLHENAPLRGTDGKPLLRHRYEIERFIADFRRNHAMNIAVLRFPGIVGASGASSTMRYLGQPTPPTLLGFDPLMQIVHEADVIGSLLHALVAEANGVFNVAADGVMPLSQMIRRVGRQPLPIFHPLAYAAGRFGFVRHNRLANQIMPFELDYLRFPWVADTTAMRGELNYEPRHTAEEALDAFRSSLRLKSYSDLLPKRKAYDGIQAFLNRRRQEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X4</accession>
    <name>A9B5X4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3130"/>
    <dbReference type="EnsemblBacteria" id="ABX05767">
        <property type="protein sequence ID" value="ABX05767"/>
        <property type="gene ID" value="Haur_3130"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3130"/>
    <dbReference type="eggNOG" id="COG2091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057011_2_3_0"/>
    <dbReference type="OMA" id="RYWTCKE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3162-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="114"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="26795" checksum="D4C6BD15ECCD054D" modified="2008-01-15" version="1">MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGAMRLILAEYLGRDPSSLEFSQNNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEEQRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRKEAYIKAHGMGLSLPLSSFAVSIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H8</accession>
    <name>A9B6H8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0229</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0229"/>
    <dbReference type="EnsemblBacteria" id="ABX02881">
        <property type="protein sequence ID" value="ABX02881"/>
        <property type="gene ID" value="Haur_0229"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0229"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_6_1_0"/>
    <dbReference type="OMA" id="FQYEIYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-232-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="288"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="311"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="39071" checksum="CC9133C5E4E98C5D" modified="2008-01-15" version="1">MSKPINLHEYEQQAMTLLDGPTCDYYAGGCEDEVTLRANLLSFEQVRLRPRFLVDVREVSTATTLLGKPLDSPILVAPSAYHGLAHAEGECETARGVAQAGSIFTVSTLATRSLEEVAAAAECPLWFQLYVYRDRSVSERLIARAEAAGYQALMLTIDRPWLGRRERELRSGFGVPAHLSMANFRDVPAAQNYRRAGPNALPDPKADMFDAGLTWESIAWLRSVTSLPIIVKGILTAEDALLAAEAGAAAIVVSNHGGRQIDGTVTTLEALPEVVAALAQSPCEIYIDGGIRRGSDALKALALGAQAIMLGRPVLWGLAVAGSAGVADVLTTMQRELQRSMALCGRPNLASIDRSLVRPSGMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R0</accession>
    <name>A9B6R0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1726"/>
    <dbReference type="EnsemblBacteria" id="ABX04369">
        <property type="protein sequence ID" value="ABX04369"/>
        <property type="gene ID" value="Haur_1726"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1726"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_0"/>
    <dbReference type="OMA" id="LWGIQIA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1753-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="34447" checksum="CFBF7A1DF1AF9EB1" modified="2008-01-15" version="1">MKAMLFYEYGNPNVLQLREVERPSLQANHVLIKVHSASINTLDWNQMTGPIMIRMLNGALHKPKINSLGLDLAGWVEAVGPQVTKFKPGDAVFGTAQGSLAEYVCATEDQLVLKPANVAFEAAAATPVAAFTAIYALSDLGKIQAGQRVLINGASGAVGSFAIQIAKAYGAEVTAVCSSRNADIAQASGASHWIDYSREDLRQHRQRYDLILGVNGYQSIFTYRKALTPTGRYIAIGGALPQILQAVALGRILSLGTSKTLQFLGVAPIRHTTLLKLQQLLESGQLKPVIDRCYRLPEAAEALRYLGAGHAQGKIVINVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B792</accession>
    <name>A9B792_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3739"/>
    <dbReference type="EnsemblBacteria" id="ABX06375">
        <property type="protein sequence ID" value="ABX06375"/>
        <property type="gene ID" value="Haur_3739"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3739"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="OMA" id="PRDGEYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3781-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="910" mass="101414" checksum="DFF6185A4F100278" modified="2008-01-15" version="1">MTKLDASFGMWLKQRRKTLDLTQDELAHLVGCATVTIRKIEANTLKPSTQIAQRLAQCCNVPEAEHTAFVHFARSETTTGPVWSDQTPGAARVNFVVDQPPHNLVDLPNPLIGRDADVATINERLANEHVRLLTLVGPPGVGKTRLALQVAQQQLERFRHGVFVVALAPVTNPQDVLSVIAQTLGIKETGIRRSFEDLKNFLYDRELLLVLDNFEQVLPAASSIDQLIQACYGLKVLVTSREALRLRRERRFAVAPLAIATPVSDEPSATFSPAVALFIERAQAVNPDFEINETSLHDISAVCRQLDGLPLSIELIAARSMLLAPKAMLRHLEHQLTVLTSRSSDHPPRQRTLRDAIRWSVDLLEPSDQQMFMHVGVFPQSCTLESLAAVGAEQAWALDLLDGLNTLADKSLLYAKADQQGETRFEMLNVLREYAREMLQHAGLLIQAAQRHAQYYLQLAQILQADLSQHNQHVTAGDRFERDLFNFRAALEFFFTQRQIEQNVQLATSLADLWYLRGYAGEGRRWLAQAIEQAQTTQTTLEPTLWIEALNAAGYLAYHQGDYGDAAQTFSQSRQLIETANDQVGMARVYNNLGLIAHWQGQYAQSEALLNDSLQIWRKLDLSMAISSLVCNLGALQLDRGELSQAAELLEQSKVLCQQQHYENRISMVLQHQGKLALYRGDYATAQRCFSESQAIAEQMSNKTVIGFALMYQGYATLAAGELEQAACYLSKAAQMSQDLGSKHMVCMVLAVQAQLAVEQAQYVVARQLFTQALELGRSMQFGTGIANALRGLALVDAIQGHYSPALEQINQAIQGYRTIGNPEGLIQSLETLAFCLTTMGYGKTIAPVVAALEQLRHEYGLRRWNNQQARWQQIQQALAQPDQSNLPAEPIVAQLLDQMPSLKLRELRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B798</accession>
    <name>A9B798_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3745"/>
    <dbReference type="EnsemblBacteria" id="ABX06381">
        <property type="protein sequence ID" value="ABX06381"/>
        <property type="gene ID" value="Haur_3745"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3745"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1592319_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3787-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="167" mass="18018" checksum="2E9C1EC6C0666075" modified="2008-01-15" version="1">MALQPDSSEQPTPAEIAQRLADVPLFEQMRPDDLAFLADHATIQQLEPAVVLSAQQSSENDLYVVVRGHLEVWLDPSSLGAEGPERKLATLFADEIAGELALVDGGVRSARLQAGDAGVRVICISQAAILNRCEQDPIFGYRLMRNLAAMLALRARLTALSAQTNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L8</accession>
    <name>A9B7L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0339"/>
    <dbReference type="EnsemblBacteria" id="ABX02991">
        <property type="protein sequence ID" value="ABX02991"/>
        <property type="gene ID" value="Haur_0339"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0339"/>
    <dbReference type="eggNOG" id="COG0769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058819_0_0_0"/>
    <dbReference type="OMA" id="FFVTPMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-342-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032554">
        <property type="entry name" value="DUF4938"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16292">
        <property type="entry name" value="DUF4938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="36180" checksum="35A812522D7DF3AA" modified="2008-01-15" version="1">MPITIEHVRVLEGPNIYYPQAGVAASLQVSHDLRDELGRQLKTWAQAVGLIIGYLRMKIEPIDDQWLLSLSFTCNHPQLGAAILQHAVEDILAGERQDEDWNHDDALFDLRRQRMRIDPVLPLLQLRAEAQGRVLPVIAVGDGMLQIGTGSGGWQFDPAQLSLGFAINPPWEQIRSVPLIAIGGVGAEIAAAQIAQGLTAAGWQQVMHIVKGDFASVRQAFLQPKAEIFVIALDHSDAVERGLAFNRCTMGVVLGISDLPETQALAAGLPALTADELGNTILLADDQRTAGLARRTAAPVVQLQRTHEPASIQQPLLALVVNQLQQLLDAGAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S0</accession>
    <name>A9B7S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1805"/>
    <dbReference type="EnsemblBacteria" id="ABX04448">
        <property type="protein sequence ID" value="ABX04448"/>
        <property type="gene ID" value="Haur_1805"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1805"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_4_0"/>
    <dbReference type="OMA" id="DLNITCH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1833-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="938"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1413" mass="153746" checksum="292142D60F30027E" modified="2008-01-15" version="1">MAKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLRFGLEHDQPYALVEPQPINLTVHDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQLADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKATLSPSFGELVPVIAEDHAYQVSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRSTWPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDLAQLTAVVAAERNAFRKHGRYRYEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQSTTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALEYHFAAIQHLLNGWLANPSIPVAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHAWAGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQPVLVLAQQAFDLPNLLLVEQLSKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQALAGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQGATLVLRNDAMLESLQRFVAACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPNVRLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLLGNGLATGYYQRPDLDALNFGQLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQRVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVVSDASLSVAELRNHASQHLPAAVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEFNDEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAAPQFLSDANLPEQIVPKQLNAQPRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAGSNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFGLDDQQWQSLIERCDLIYHNAAMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAHAGLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVPRGLLPSLPVEEIWNPVDFAAQTIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAVQLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAIGTIENKRLLQTLAAHGIAVPVIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U9</accession>
    <name>A9B7U9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX04477">
        <property type="protein sequence ID" value="ABX04477"/>
        <property type="gene ID" value="Haur_1834"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1834"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478800_0_0_0"/>
    <dbReference type="OMA" id="PCPEVFV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1862-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="215"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="448"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
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            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="569" mass="63784" checksum="2D20723BC8EC42C6" modified="2008-01-15" version="1">MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFFSERYSFKGIVLSITGFLYVIYVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSGFFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLVRALENALRQSLHLQANLQHLVDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPLNSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLAESKGLQIAYHHADGTGLAWADSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISVHDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSITKQLVDLHGGNITVESELGQGTQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSREALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSITRPWPHALDDFLHQTLTQAQQQQQLASQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z8</accession>
    <name>A9B7Z8_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3294</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3294"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05931">
        <property type="protein sequence ID" value="ABX05931"/>
        <property type="gene ID" value="Haur_3294"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3294"/>
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    <dbReference type="HOGENOM" id="CLU_028014_0_1_0"/>
    <dbReference type="OMA" id="WRYRRWE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3331-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glyco_trans_4_4"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="17"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="45422" checksum="B452C292F288766B" modified="2008-01-15" version="1">MRILFLTPYPAYPANSGGTQRMFQLLRELSRQHELWCLSLSPSHSASAAAQPLNRYCHLTLIPAPRRNLTQRAWTTLTSPLPDMALRAPSETFRSALASLLNTNRFDLVQAESIEMAQYALQAQRWGIPATLDQWNAEYVLQQRAAQTDRQQLKRWHAALYSAIQWRKLARYERFVCNQLDQTYVVSPEDRTMLQKIEVKKTLHVVPNGVDSQQFSPNMPREYDPNTLLFTGSLDFRPNIDALRWFIQEVLPLIRAERPETKLMIVGRAPTPAVLQLAQPSVIDIIPNVPSVQPYFNQAAVFVLPMRMGGGVRLKLLEALATETPLVSTTMGADGVTGLVPNQHCLLADTPAEFAQATLKLLHERQFAQGLAMAARRFVAANYDWQAITERLQQAWGEISHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B843</accession>
    <name>A9B843_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3340"/>
    <dbReference type="EnsemblBacteria" id="ABX05976">
        <property type="protein sequence ID" value="ABX05976"/>
        <property type="gene ID" value="Haur_3340"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3340"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_488989_0_0_0"/>
    <dbReference type="OMA" id="SEGREWH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3377-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="345"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="557" mass="59515" checksum="6D6E0CA556B618D2" modified="2008-01-15" version="1">MTESVAMTEQPSQTAAITLPRSPLSRLLLPIALVVLALGAGLAAWSGFNFGPQTMLIGAIAGGVGALAALVGLIAGLRRRLPLSGWALIVGTLSIALGATMVFPEQRELAIISAALPVLCAALTLRPLHTAIVTVVSLASLWAAAYFAAAEPSTNQLIQWSLLSAFVLVISIFALVCSAALRAFDRQQTVGHESTTQLNKQLGEEQERVERAAQLLVQERDRLAAVLGAASDGVVLADSNGIILQANAAARQLLNEAFGGTLEGQALNQWSQENTGRLRVISNEREGERQRVVFEQQQGTRKPVIGLNQVPIRSSAGSVLGYVGVFHDKTTELEVEEMRSQLLDFLVQDMHDPLNSVLAAQDTLLAGDLGDGNERVLSTARRTTSRLVELTNTLMEMSRLHGDPNSLHRLANPLRPLIEGSIAQSTPQAQQRAINLVLEYGADSGGLAFDADKMRRVMSHLLDNALRRSPAYSTVRVQVSNTGGNAQVRIADQGPSIPVELAGRIFDRFSKQVGEQRIGGVGLAYCKQVIEAHGGRIWVDSTPGKGSTFIFSMPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9B868</accession>
    <name>A9B868_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3365"/>
    <dbReference type="EnsemblBacteria" id="ABX06001">
        <property type="protein sequence ID" value="ABX06001"/>
        <property type="gene ID" value="Haur_3365"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3365"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_71_0"/>
    <dbReference type="OMA" id="PDYLQPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3402-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="227"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="509"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="733" mass="81895" checksum="F737AC1856A16F35" modified="2008-01-15" version="1">MLRWATMKSLIAHKLNRWFMLAALVIIVNGLLSWQYLQTIQANNASVIESETMTNRLDRLLSLLKDAETGQRGFIITGSEQYLAPYQTAQTELPSLLAEIEAYSSQRPLFIERLPELKTLIAEQQQELSTTIDLRRSQGFEAAQAIVLENQGKQHMDSIRQIIDQLLDRENIRALDRAAQTKLNVQRAGLALAFATLVATGFVIGTMALTERDVRRRELAANELRNQREWFAVTLASIGDAVLTTDIDGKISFMNHIATTITGWPEQQALGQSIHTVAAIFDPITKQELAHPVNTALAQRQIVTLSNSVVMRQGNGYVAIEDSAAPIYDREQQVIGAVMVFRDVSERYRDEFGQRLLRTLHNRLAATIDLAQVLETSTAVPTPSFSAACGLYLLLDADEEPLSSYSSAHEPLLNWQQHPAFAAALANSQAQIIDQALPEPYHSAIIIPFRDQHQLSGAIVFLHDQHRFDQIDVELAEELSQRMVLAIEQAYLYRQAQNAVRLRDVFLSIASHELKNPLTTLLGQSQLSLRRLERLNLVDERLQRSLQAIEAQASRMNKMVTALLDVSRIETGQLDIQHDQIDLAQLLQQLVNDLAITIDHHQLSYHCTSSQPIQVVGDPIRLEQVFVNLINNAMKYSPEQTEVLVRADRNAQQAIVQIRDHGIGIPAESIPNLFTRFYRASNAARSHVAGLGIGLFVVKEIVDLHGGSIEVSSQVGQGSLFTVYLPLQTGNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8A4</accession>
    <name>A9B8A4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3821"/>
    <dbReference type="EnsemblBacteria" id="ABX06457">
        <property type="protein sequence ID" value="ABX06457"/>
        <property type="gene ID" value="Haur_3821"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3821"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239367_0_0_0"/>
    <dbReference type="OMA" id="LMHWLDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3863-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="49"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="23126" checksum="BE25FD21C9D43985" modified="2008-01-15" version="1">MQAFLTNIAQRPALWAMLRRIVENNYVGERAAIADELTPWLQTKPRRFLDFGCGTGEFASSFPQHSYMGVDLSQGYVRYAATLSDHRFGVMNGNALAFGDASFDAALIVGVIHHLDDALAQITARELHRVLAPGGEILMLEDIPAQDWWNLPGRLMHWLDRGDAIRQDEDYGRLFAPYFTIQRRWTIRSGICDYAVYRFSRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8T4</accession>
    <name>A9B8T4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07748">
        <property type="protein sequence ID" value="ABX07748"/>
        <property type="gene ID" value="Haur_5120"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5120"/>
    <dbReference type="HOGENOM" id="CLU_1183747_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5182-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732010" evidence="3">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="24364" checksum="4DDADBBB963ACF4F" modified="2008-01-15" version="1">MRWFLILCMMLLSPFIAAAQTTPITVRVQDAATMQPVAGVVVTFTPVGGHPITATSDAQGMAVVALPADRLVVTLAAADGRMMPWEAPYAAGYPMQSVVGLTTFTVQIDGATQVAHHALDQDWAGGPTQADDPTAALAPPATGTALAAQTVTVEVAQLPTSEAVPPTRTLPVASPTSLPSPMPTSSQPVLAILPSSPPTPPAARPWTLWLPILVMVGVLLLALWSWRGRTGVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z5</accession>
    <name>A9B8Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilT protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07809">
        <property type="protein sequence ID" value="ABX07809"/>
        <property type="gene ID" value="Haur_5182"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5182"/>
    <dbReference type="HOGENOM" id="CLU_118482_5_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5244-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="16781" checksum="89EC32CEB0320A06" modified="2008-01-15" version="1">MFLLDTNHCSLILQGHPIVLDHLAAIGQTPVMTCVIVQGELILMAERSARRAENRRTVDAFLREITIFSIDQITAHTYGSLKAAVLQQFGPKEKAKQRHTALHQLGFSENDLWIAAIALQYQLTLVSMDSDFQRMQAVVSLPTVRWDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B921</accession>
    <name>A9B921_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07835">
        <property type="protein sequence ID" value="ABX07835"/>
        <property type="gene ID" value="Haur_5208"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5208"/>
    <dbReference type="HOGENOM" id="CLU_989620_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5270-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="33505" checksum="2EC4A427CD00A04B" modified="2008-01-15" version="1">MEEAANMNNKLNQKELSKGFMKEWHKLSIIGSLAMTIFLTLLYLYVNDKSGQLTTDHRMELFSNVIVNIIPVFLLYAMSSLFLKNMLDLKSKNDQQEMLEQIDQLYQYNFLKDKNFNDIGVNNIYDNMNAWNYREKVLVAKYEVRILVTLMEDTFFLVDKIERNKPTCKYKILMLDPESTIARKRSLELHYNEDYIRIKIESRLSELKKIKEKYGLDMEIRFYGAMRSMYLCICDKTALVGFFWHRERAAVRPMMEISLDSPFGYLIDEEFNTIWNDSRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD9</accession>
    <name>A9AUD9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0407"/>
    <dbReference type="EnsemblBacteria" id="ABX03058">
        <property type="protein sequence ID" value="ABX03058"/>
        <property type="gene ID" value="Haur_0407"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0407"/>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026231_0_1_0"/>
    <dbReference type="OMA" id="YYSAPKQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-410-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="147"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="472" mass="52911" checksum="62C9B8577B8A121B" modified="2008-01-15" version="1">MSNPAQNEIEFDYSKYGFRDEENYTFKSSKGLNADIVRTISEMKGEPEWMLQRRLKALEIFHKKPLPVSGVWANPRLAELDFQDIHYYVRPGERAENNWDDVPESIKNTFEKLGIPEAERKFLAGVGAQYESEVVYHSLREEWEKLGVIFLDTDTGLKEYPELFKEYFGTIIPSADNKFAALNTAVWSGGSFVYVPKGVKVDIPLQAYFRINAENMGQFERTLIIVDEGAEVHYIEGCTAPVYSTNSLHSAVVEIIIKKGGKCRYTTIQNWANNIFNLVTKRAVAYEDASMEWVDGNIGSKLTMKYPAVYMMGRGAKGEVLSVAYAGEGQHQDAGAKMVHGAPDTTSRITNKSVSKNGGRTTYRGLAKVMRGAHNAKINVVCDALILDNRSASDTIPYIEIEEDSATVAHEATVGKIGEEQLFYLMSRGLDEAEALSMIVLGFMEPFTRELPMEYAVELNRLIQMEMEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUG9</accession>
    <name>A9AUG9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase M4 thermolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_0437</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0437"/>
    <dbReference type="EnsemblBacteria" id="ABX03088">
        <property type="protein sequence ID" value="ABX03088"/>
        <property type="gene ID" value="Haur_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0437"/>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010362_0_0_0"/>
    <dbReference type="OMA" id="FEDWENG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-443-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734985" evidence="8">
        <location>
            <begin position="27"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="98"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="248"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="368"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1017" mass="108419" checksum="C37E41CC74EAAF47" modified="2008-01-15" version="1">MRSMRMLRLLAVLIVVSMLPLSRSNAQTPTTNSPINRLLSQGANVARHSQTGYVRWIGAAAGTTLDQPVGLNRADTLNIANAYLAEYGNLFGLAQASDATVAKTSTTQDGRQVVRYKQRYQGVPVIAGELQVQVNQAGELLSINGEVLPNLNLNTNPKIDQAKAINTAQTYVATKYDVNLAALNVSKSELAIYNPALLGGTGLQKSSLVWFVTVESTSSNPIREYVFVNAQSGEISLAFNQIGFAKNRFVCNDNNVVDNDDNPNNNCDQPSEYVRTEGSAASNDADIDAAYDYSGDTYDFFNLFFGRNSIDNNGMNLISLVKHCPPGAGCPYGNAFWNGRQMTYGQGFAAADDVVAHELSHGVTEYTSNLFYYFQSGAINEAMSDIFGEFMDQTNGSADDDETTRWIMGEDLGGIRNMQDPTQGDQPDRMLSELYVLDPNLLDSGGVHSNSGVANKAAYLLSDGDTFNGQTIASIGITKTAHLFYETQISSLTSGSDYADLASALRQACTSLTGSHGITAADCVEVNKTILATEMDLQPTNAPAPDIAACSPGQTQTTVFNEDFEALPNNRWSASALSGSTETWTTNPAPLVGTYATSGSGSATNYNGVYGWNQAVEESAFTQNASVTVPANGFAYFRHAYDFYAPIDAGVVEYSTNNGSTWQSAAGLFSFNGPTNIAEDGAFGGEQAYVGNSNGYNASRLNLASLAGQSIRFRFKVALGDTPTPNRSVTWSIDDFEIYTCNGPAAPAAPSLFLSSDVLVQQGKQTSATIGTASDDLDLAGALTVSTAGAPTGMNVSISNQAGILKANVNCACSSAVGTYPITVTVRDSGNLTASQVFNIEVEPAGQSLINGGFELGTNWQAFSNSFSDVSPPLCSLPGCAGAPRTGTSWLRFGARSGTTETAFAQQTFTTTAGDATLEFYLSIYAHNGRGIQDYVKLSLDGEEIFRVSDANTEYDNGYAKVTIPLTDLSAGEHVLRFDSVNNSTANIVRFSIDDISFVTETNQCRGSNLYLPMITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI5</accession>
    <name>A9AUI5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_1869</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
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            <begin position="21"/>
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</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ3</accession>
    <name>A9AUJ3_HERA2</name>
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        </submittedName>
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        <lineage>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
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                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="entry name" value="AMP-bd_C"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
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        <location>
            <begin position="961"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="996"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX04520.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1525" mass="167718" checksum="9B92B185C4EBC651" modified="2008-01-15" version="1">MSDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEILRTTFHYLQGMALPLQVVTELSELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWLGREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPTTDEPMQYIDIAEWQHELLEAEETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLAVPASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQFGQLVKQVQQEYVEAYAWQESFHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQRATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLIEQYQTLLTAALSNLNTSLAQLPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEARSNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFMLGDIQASIVVSETSLQAQLPEHAADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSGSTGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTFAADLGHTAIFPTLTNGGTLHLITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWKLLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDVHGQPVPLGMTGELYVGGAALARGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPDGKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAVIVRDDPAGDKRLVAYLVAGQQRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIVAPRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFDHPTIADLAQVVATTTADQQAQQQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFDLDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVAVELLHINLAAAPAEQQRQLMEQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYEQIRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAHANTVASTQNLSLHLSVEETKALLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELEGHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSLRATKEQLRQIPQRGIGYGLLRYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYLDLTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPSANLNQKNLDSFIAKLRNSENSTHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUW5</accession>
    <name>A9AUW5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ordered locus">Haur_3919</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3919"/>
    <dbReference type="EnsemblBacteria" id="ABX06553">
        <property type="protein sequence ID" value="ABX06553"/>
        <property type="gene ID" value="Haur_3919"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3919"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_0_0_0"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="32487" checksum="F539A1D9A3F784AC" modified="2008-01-15" version="1">MAVLYVVATPIGNLEDISPRGLRILQEVGLIAAEDTRHTRKLLQRYQIETRLIAYHEHNKLARLNTILLALANGDDVALVSDAGTPAISDPGYELVGAVIEAGFVVVPIPGPSAVITGLSASGLPTDRFYYLGFPPRRSKERCALFSEVVDIPATLVLYEAPHRICESLADALSVLGDRPAAVARELTKLHEQFVRGTLSELLAHFNATEPRGEFVLMIGGATRPAKRKPSSTSTNELGVAVTTDEAPVAVDWDLIRSELQRLRAEGWTGTKAAKHLAKHYELDRHQVYSEWSNLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA5</accession>
    <name>A9AVA5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0535"/>
    <dbReference type="EnsemblBacteria" id="ABX03183">
        <property type="protein sequence ID" value="ABX03183"/>
        <property type="gene ID" value="Haur_0535"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0535"/>
    <dbReference type="eggNOG" id="COG4712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1728847_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-544-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="16873" checksum="0C6D61C989AD47DF" modified="2008-01-15" version="1">MTQPFTTIKPKLEAPFPMDIIEIKPTVVTKDKTRALAIAYAEVRAYQDRLDAVVGGEWAVTYRPLGPGAVICQLTLVGITREDVGEAEQTDPNKATVAVAQAFKRACSAFGLGRYLYSMPKVWAEYDQEKKCFVYPDRIIAHMYKQIGIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN0</accession>
    <name>A9AVN0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3998</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3998"/>
    <dbReference type="EnsemblBacteria" id="ABX06630">
        <property type="protein sequence ID" value="ABX06630"/>
        <property type="gene ID" value="Haur_3998"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3998"/>
    <dbReference type="eggNOG" id="COG0573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033621_1_0_0"/>
    <dbReference type="OMA" id="ETMALYM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4040-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="95"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="321" mass="34609" checksum="1C1288E796AC5373" modified="2008-01-15" version="1">MDDKVSIGMDSRRITTTQRETTRPFSLKRQPRLGESIIQGFLLFCGVLSMFTTIGIVVVLGSESIAFFRQVSIVEFVTNTVWSPQIDEFGILPLLLSTLLTSTIAMFIALPTGLAAAIYLSEYASSRARSILKPILEVLAGVPTVVYGYFALKFMTPVLKAVFGEANVNIYNMASAGLVMGIMIIPMVSSMSEDALSAVPRALREGAYGLGATRLETAIKVVLPAGISGIIAAFVVAISRAVGETMIVAVAAGAKPTFTFNPFEAAETMTGHIARISGGDLSYASIDYNSIFAIGLTLFLMTLGLNMVSRRLVRRFREVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT6</accession>
    <name>A9AVT6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4054"/>
    <dbReference type="EnsemblBacteria" id="ABX06686">
        <property type="protein sequence ID" value="ABX06686"/>
        <property type="gene ID" value="Haur_4054"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4054"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_280031_0_0_0"/>
    <dbReference type="OMA" id="YELRSIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4097-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="686"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1123" mass="128586" checksum="5D9A998E4AB1E55B" modified="2008-01-15" version="1">MKYIMRVISIFFGCFVVISMAISVRTSLNTIDDPALELITYWSAINNCNEIHAITPAEWMPIAQEIVAPGDCILSVSGYGYNSPEMIDHLKKKLELDYANRFVPVEIRRDQSQFTVYLPITKISIHHILQIYLAIILTAALLWILGIIVLISNPDKENNIVFGYILWFLALAITSIRHRVPDFGEYLTLVATVVPLALLGGSFFHLGYIFPVKIERYHGFKYVLYIPSLFSIALYTYVIINIASGKSNIPTISNQANYIIATIFIIGFSFTLIRWAYLWITYRHQTKSKIILQAKIAFTTWLIGGLFNVILMIVYQEFNLKLPIIGKSIFFGLFLLVIPAAGTAFTLLRYESVHAKRSFSLDLLMIILISAVIVDISILINSYIEINGIIFINIFFVAVITSIFWYIDNPFRRIFEKYFLRHQNDAEILFGLLNHLDITKDIHSAIYSSIDYLTKQLEIESLRFVIEKNIIKTSEHFYIMENEPIDLFFEHNSEAGSFSNSLSKFYKHREIVYDNNNNQIGYLYLGPKITNEDFDTKDYELIRLITQYLSWFVLAKNQLILINQIIQRIIKARDSIFGDINHVIHDDILGKLNSVTLGIDMICEFDQITPDTKARLVQYKASTDQTVEILKRFIIQKQIAIPGVKKNFLPEIHRLIRELIQHQQIELHWEMPPRDDLNLWNNLSIDKKRDIFRIIHSAVANTLAYAQARNINITFSKNNAMLSLSIIDDGVGFEIDKDIKQNSTGLMTMYERTKNIDGIIEIRSIIDQGTTIELSIPMEIAIPTLIHEQSTEQATPLIKKPKLEMLHSDIQVKEQSKKYNLALICMAFMLGIGITFILKTDLLSLEKVASQPKVWFDVDVRLVNQQAENGEFWRTRLFDGSRFIQNYDTIAVGTRVTMTFSLRNHKAKPALLRNLVAGARGPNVLEQGWSASTMDFPSVQNILIEPYKTYTFTASRIYDQPGNYFLEPMFEDEAGDWRAIADFTRITFFVADLTNPIVSEVVEVAADRDWKYTPIYVQPGDTIEFIAQKGSWTTDMNSLPFVNADGYQNQHYDWTTLPAANYGQLIGSIGDWKFAIGKESSIQAPNYQGILRLGINDAHCADVCLSDNRGSMMVAIVVRRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVX4</accession>
    <name>A9AVX4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0564"/>
    <dbReference type="EnsemblBacteria" id="ABX03212">
        <property type="protein sequence ID" value="ABX03212"/>
        <property type="gene ID" value="Haur_0564"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0564"/>
    <dbReference type="eggNOG" id="COG4373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038244_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-573-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="477" mass="53116" checksum="49A90BF94C661951" modified="2008-01-15" version="1">MSKAVELAKCHADPAYFTHNYGRIDDAQGLGDGSGDMPFTLWPAQIEVLWTLLLQRLILILKARQLGISWLCCAYALWLCLFQPGKVVLIFSKGQGEADEMLHRVKRLYERLPDWMREASPALVTDNTTELEWANGSRVKSLPATKGAGRSFTASLVILDEAGFLIWAKQLYTALKPTIDGGGQLIVLSTANGIGNLFHQLWVKALSAKNRFKTIFLPWWARPTRDAQWYQEQLEEYTDLDMVRQEYPSTAQEAFLVSGRTRFKMPWLLQQTPSDGLAAESLPDALDKLDGVTMYQLPQQGRRYILAADVAEGLEHGDFCAATLIDAVSWEEMVSVHGKWEPDEYARILMALSDGYGATVAVERNNHGHAVLTTMKLAGFTRIVYGLDGRAGWLTNAQTKPQMIDLLATALRDVLVKIRNQTALNELAIYRILKNGGTGAPAGYHDDFVMAWAIALMVASQPTEVEDEAIAGSWDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY7</accession>
    <name>A9AVY7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRISPR-associated RAMP protein, Cmr1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0577"/>
    <dbReference type="EnsemblBacteria" id="ABX03225">
        <property type="protein sequence ID" value="ABX03225"/>
        <property type="gene ID" value="Haur_0577"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0577"/>
    <dbReference type="eggNOG" id="COG1367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043263_0_0_0"/>
    <dbReference type="OMA" id="FWWRATR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-586-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007522">
        <property type="entry name" value="CRISPR-assoc_prot_TM1795"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01894">
        <property type="entry name" value="cas_TM1795_cmr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="439" mass="49428" checksum="7D74A4B7E060B9AD" modified="2008-01-15" version="1">MMFNRKPSAESSVNCPDVKKIENHKPPIEPIIRNYRLITPLMGGGVKAGENDSNFLIRPSSIRGQLRFWWRACFGGSHQPQSHDALLADMFARESALFGKAADSQSSGASAVQVEIEVINSGSQFRVIAKNGQEVKISAMNSPYGYSAFPLQDKQNASVREGIEFKLTIHLKSAEQREELEKVLWAWQTFGGIGARTRRGFGVLQALDKANHRFAFANKAELQQHIRAIIGNRSYWPNGVPHLAPTMQLRLIKPKPNQTALNIWADLLRCYKEFRQQRNDGNQPNRPGRSRWPEPDALRRLTRQRSRLHEQPLSTIDAFPRGEFGLPIIFHFKDSDDPGDSELRLQANHEFSQQKGDRFASPMLLKPVASTGQLFGLIAVFEGSTLDGRQAIIKNRRITAAAVIIDVSESQARTIVDKQRRPMLTNPSIITSFLETIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW72</accession>
    <name>A9AW72_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04722">
        <property type="protein sequence ID" value="ABX04722"/>
        <property type="gene ID" value="Haur_2082"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2082"/>
    <dbReference type="HOGENOM" id="CLU_1765534_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2110-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="147" mass="16915" checksum="F9706C50E719EC03" modified="2008-01-15" version="1">MGSSKQIFLMLPPHDPLPLIAGLETLGYKPDPWNKTSLVGMRQAWGQDGTVDIYTSSETFVWKADFPAVCEQITAHVGTDQWMHYVIYFTYHPQAEAALLKLIDWMHTQYPQLTVVTSLHHVFSPDHLPLKDRAMLYWGNDPWDDED</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-04-25" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD6</accession>
    <name>KOSYN_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">(+)-kolavelool synthase</fullName>
            <ecNumber evidence="1">3.1.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2015" name="ChemBioChem" volume="16" first="772" last="781">
            <title>Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus.</title>
            <authorList>
                <person name="Nakano C."/>
                <person name="Oshima M."/>
                <person name="Kurashima N."/>
                <person name="Hoshino T."/>
            </authorList>
            <dbReference type="PubMed" id="25694050"/>
            <dbReference type="DOI" id="10.1002/cbic.201402652"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biosynthesis of (+)-O-methylkolavelool. Catalyzes the biosynthesis of (+)-kolavelool from (+)-kolavenyl diphosphate via the release of the diphosphate moiety through the nucleophilic addition of a water molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(+)-kolavenyl diphosphate + H2O = (+)-kolavelool + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54672"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138311"/>
            <dbReference type="ChEBI" id="CHEBI:138313"/>
            <dbReference type="EC" id="3.1.7.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diterpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.7.12" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AWD6"/>
    <dbReference type="SMR" id="A9AWD6"/>
    <dbReference type="STRING" id="316274.Haur_2146"/>
    <dbReference type="EnsemblBacteria" id="ABX04786">
        <property type="protein sequence ID" value="ABX04786"/>
        <property type="gene ID" value="Haur_2146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2146"/>
    <dbReference type="eggNOG" id="ENOG502ZJEY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962320_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2174-MON"/>
    <dbReference type="BRENDA" id="3.1.7.12">
        <property type="organism ID" value="2656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000443952" description="(+)-kolavelool synthase">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000269" key="1">
        <source>
            <dbReference type="PubMed" id="25694050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="2">
        <source>
            <dbReference type="PubMed" id="25694050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <evidence type="ECO:0000312" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="33593" checksum="3810389A368B086D" modified="2008-01-15" version="1">MRPTPTLAEFLHAPLTTIRQVAPATMVFSSGGSRRKAALANMSAAGEEYARWSHQQLLKCLELFFSHGIKHLFLPMLLPNQFQETTPNYREHIEQWVAWGAASQTMLEYYQEHNWRVRLLDTQYSPILADAAQRLQQPYDHPDQPTLWWFVVRDSEDPWQIIFQAAQKTVFKTRSQAIEAIYGEPIPPAELFVSFGKPQVNHDLLPPLLVGELQCYWTQKPGYTLSEEEFRQILYDFAFLRKTWQVDKTERTQAALAFRQHWERGPILGLGQQLGPFWYPQSTSIESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE8</accession>
    <name>A9AWE8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4075"/>
    <dbReference type="EnsemblBacteria" id="ABX06707">
        <property type="protein sequence ID" value="ABX06707"/>
        <property type="gene ID" value="Haur_4075"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4075"/>
    <dbReference type="eggNOG" id="COG3294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081221_0_0_0"/>
    <dbReference type="OMA" id="ICPVMEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4118-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="100"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="290" mass="32190" checksum="E81B940FC8F8B699" modified="2008-01-15" version="1">MEMRDDARLADEVEKLSHTADTLSLDTKDRMRDVVAPKIEAAVAQREAMVAELTSQPVQAPASELAKADPRRVTITQVRNHPHTYAYLDAANNQLKLIGYTEHGRRHASLVGHIGANVLRRLKFSAREIELAEIAGVLHDIGNSINRNDHGQTGAILAKDILSSLDMPIDEIITIMGAIGNHEEERGHAVSTVAAALILADKSDVHRSRVQNSDPTTFDIHDRVNYAATKSFLRVDTEQRRVTLQLTIDTEMASVMDYFEIFLSRMVMCRRAAEFLGSRFGLSINDVSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG7</accession>
    <name>A9AWG7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4094"/>
    <dbReference type="EnsemblBacteria" id="ABX06726">
        <property type="protein sequence ID" value="ABX06726"/>
        <property type="gene ID" value="Haur_4094"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4094"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_6_2_0"/>
    <dbReference type="OMA" id="LRMLMMN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4138-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="113" mass="12549" checksum="06A608893B16EBED" modified="2008-01-15" version="1">MAELIQETNGKVLIVRLPARMDAAAVRELEEPFAQSIADHNGPVLVDVSKVDFAASLALRMLMMNLKDQQNRGQNLMLFGLQTQIAEVFRKTRFDTLFTIADDEASGIEQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWM9</accession>
    <name>A9AWM9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4156"/>
    <dbReference type="EnsemblBacteria" id="ABX06788">
        <property type="protein sequence ID" value="ABX06788"/>
        <property type="gene ID" value="Haur_4156"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4156"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="EMGSDDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4202-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="232" mass="26186" checksum="529279F6CEC3046B" modified="2008-01-15" version="1">MQRILIVDDEPSVVDVVRSRFEREGFAVGETGSGEDALVRLRNETYDLLILDIGLPGIDGFGVLRQMRAEGFEQPVIMLTARADEVDRVVGLELGADDYVVKPFSPRELVARVRALLRRTAEASRLRQQIGDAAPTSSGLQLDNARRRATFRDVQLTLRPKEFDLLAYLASHPGQVFTREVLLGQVWGYDEYVDARTVDVHIRRLRSKLSEIDAESNLIQTEWGIGYRFIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU6</accession>
    <name>A9AWU6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0699"/>
    <dbReference type="EnsemblBacteria" id="ABX03347">
        <property type="protein sequence ID" value="ABX03347"/>
        <property type="gene ID" value="Haur_0699"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0699"/>
    <dbReference type="eggNOG" id="COG1769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044328_0_0_0"/>
    <dbReference type="OMA" id="GWYTSEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-711-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019117">
        <property type="entry name" value="CRISPR-assoc_protein_Cmr3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09700">
        <property type="entry name" value="Cas_Cmr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="484" mass="54048" checksum="D67E807DF6FB4F84" modified="2008-01-15" version="1">MNTRRERSKQKQQAKKQNSSNTQVIAQNLVAPINDQVDELISVSNNSIQPEASADQPANAEITTQQAWLIEPRDPLIVRDGRPFNNTPGARAYTQSFPPPSVLAGVIRSQTAYASKLQFTRNSDDNRHQGNKLQPIQIYGPVLVELLEPNEANAEAEFLCPAPADALLFEPESKIEDKPSESVPWLRRLIPIQAPAKLVSDFNELGLVGLVEPDPRKPAKEQPHFWYWKRFLQWLQDPAGLIDQTQTAAVQKSTDLGIQGLPIDQRTHVEIKPDSQQAEDGRLFQTRGLSFTQANDQRLAEARRLALYVHADYRDTTGLTIPQPSIAPLGGERRLARWEPTERQLPACDQAILDAIVKANACRVILLTPAMFAKGYRPTWLFEDPRGVQPKLAAIAIKRAQGISGWDLAIHKPKPTRRLAPAGTVFFLTFPEKENSAAIEAWVRNYWMHCISDAEQDRRDGFGLAVLGAWDGKLAKIKGVPNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX21</accession>
    <name>A9AX21_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2189"/>
    <dbReference type="EnsemblBacteria" id="ABX04829">
        <property type="protein sequence ID" value="ABX04829"/>
        <property type="gene ID" value="Haur_2189"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2189"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2217-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="11"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="12157" checksum="6B686B779078DDD0" modified="2008-01-15" version="1">MSIASQTKVINIGILTLSDRFDIAALSTFRQAADHILAQTNYLVIDMAAVSFFDSAGMAALVNVLKRVREQAGDIRVVWPIAEAARRIVSLTKFDRVFTSSPSVESALSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXD4</accession>
    <name>A9AXD4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4222"/>
    <dbReference type="EnsemblBacteria" id="ABX06854">
        <property type="protein sequence ID" value="ABX06854"/>
        <property type="gene ID" value="Haur_4222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4222"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_239187_0_0_0"/>
    <dbReference type="OMA" id="QPEWATT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4269-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r1_1" evidence="3">
        <location>
            <begin position="836"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="658"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1556"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1757" mass="190962" checksum="B68967624E2675C8" modified="2008-01-15" version="1">MALTTIQALYDEARSALETGKEERAIGASEHLLESFPYYLEAYRILGESYLNRQDLAKAVEAFERVLRSDPENIPVHVGLGVTYERQGNLAAAIREFEQAFEIKPDLPELRSQVLRLYTEAWGSENARILLKKAGLGRMYVRGRRFDKAIQEFNDVLADDPKRVDIAVALAEALWRNGQEAEAAEVASDILRDYPDMLKANLILGYHLLAAGDPKGRKLWQHAQQLDPSQGVAYALFDGMLPPVEAPDTKIEAFDEAAWKAKKAEKAEKERLAREAAEQAERDRLAAEQASKAPAASWLAEVEAAPVAVGVAANADDDFLRSLLFGDFGAAPASPAPTAVAIAEPEYDVDFNLDDLGLDLQPFSLDEVDDTPSNKAPTPAPEPVVAPTKPAPEPVVASNDDFELPGDLTPFSFGDWDESSIDDIPGTGADTGKLPEQLQPFSLENFDDVQPETSSKAQDDDLALPNTLKPFSLDELSFDSIDTPSEPSMPFSRDLPSFPDTDQESGGFSWQQPRSRSRSIFGAQPEPEFNQDEEDDAGIFNRMVIKKQTQTLPPLVEPVYDPADSDDEAMNFFSNDDVDLRNYDEHDLHTADTEPAITPFSLTELGLDADEIADYNAMGNLSQPQTQVDEELEIKPFSLTELGLSDDEIALLQAGEDSALPTDPTNDESGLTPFSLNEFGFDTPATNDDQGFNFDEPSITPFSLDNLGLDPEEQALYSGEFNPAPVAEPTPKVEEEPNMTPFSLTDLGLDADEIAQFEAMNQAPAAIDDDGFDGGLQPFSLDDLGFDQEPQAYEEPVRELSDSSQPFSLNDIGLSAEEIAAIEQAGQNQSDDPIFDALLGIGQQQGYVDLTDIINQFDDPESQTEEIDRIALALHDNGIQIRDGDEVINMDEEFSGDEAEAYETEEPLENFIAGDFDQPTAEVEPEMTPFSLTDLGLSAEEIAMLNGETSEAPTEEPAPFSFDNFELEQPSAEVEPEMTPFSLTDLGLSAEEIAMLNGETSEPAAEEPAPFSFDNFELEQPATDAEPEMTPFSLTDLGLSAEEIAMLNGETSEAAAEEPAPFSFDNFELDQPATDAEPEMTPFSLTDLGLSAEEIAMLNGETSEAAAEEPAPFFFDNFELEQPATDAEPEMTPFSLTDLGLSAEEIAMLNGDTSEAATEEPAPFSFDNFELDQPATDAEPEMTPFSLTDLGLSAEEIAMLNGETSEAAAEEPAPFSFDNFELDQPATDAEPEMTPFSLTDLGLSAEEIAMLNGETSEVAAEEPAPFSFDNFELEQPSAEAEPEMTPFSLTDLGLSAEEIAMLNGETSEAAAEEPAPFSFDNFELDQPATDAEPEMTPFSLTDLGLSAEEIAMLNGETSEAAAEEPARFAFDDFEFEQPSAEAEPEMTPFSLTDLGLSAEEIAALEGTSAPEPEIEAEEPDMSPFTFDQLGLSAEEIAALEGNEAPAAEPASELEPDLTPFSLADLGLSDDEIASLQQGDDDRSLKLSEEELMGIDFALPSAEPEPEPVVEAAPAEPEMTPFSWEDLGLSDDEIAIIESPAEPVVEVTPVVVVPTPPAIVETPPAISATPTPKAEPEADNKRAPLYPVSSRPREEEQRPRAPLYNVSPRREPKPAAETPVVETSPVVAQTPTPVAVAPVASPTVTPSSGGASGDGPDFSEYYQQLEADPNNHGLRMALARMISQTASVDQALNEYKRLIKQNQLMDQVVDDLQDLIESHDDPGLLQRLHRALGDAYSKQGRWREAMDEYGWVLNKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ9</accession>
    <name>A9AXQ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C14 caspase catalytic subunit p20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0825"/>
    <dbReference type="EnsemblBacteria" id="ABX03473">
        <property type="protein sequence ID" value="ABX03473"/>
        <property type="gene ID" value="Haur_0825"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0825"/>
    <dbReference type="eggNOG" id="COG4249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029389_3_1_0"/>
    <dbReference type="OMA" id="FDSQHIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-839-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="33147" checksum="D7159025D6436A03" modified="2008-01-15" version="1">MGIRGLFVGINSYSERPLKGCVNDVTAVRELFRTQHAAADDQLRLVTDAAATRQAIIDNLGWLAEPLNDGQPEIRIFHYAGHGVQHPDQNGDEPDGADECLAPIDYPSAGLLSDDHLAELYQGFLGTTRLILLMDCCHSGTISKDPFSDIRYRTLTPAKVVYDEIRAKKQAYQQQQVDNVAQQILDLQQRSADPSEIAKFAGELVSSLQKQSFGQRPQHENTILISACKAEQVAADANFGGTYHGAMTFFLKNILSENPQISYANLGEQLRRSLYDNKFQQIPQLECPNSLINQPFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT1</accession>
    <name>A9AXT1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2257"/>
    <dbReference type="EnsemblBacteria" id="ABX04897">
        <property type="protein sequence ID" value="ABX04897"/>
        <property type="gene ID" value="Haur_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2257"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="OMA" id="QAEHMYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2285-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="71"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="828" mass="92612" checksum="8136C97CA4546F05" modified="2008-01-15" version="1">MTTLPNAETLQQAEALLAQIPLDRIPAHQRPRADWMLDDQFPISSFVGREDLLKQLAAAMASTTPTMIVPTLAITGMGGIGKTSLALEFAYRYGHYFAGGVYWINADYTPIATTAATILPSVDRLWQKLFPQRDSSQISPEQRLNEIKSFFNSPIPRLLIFDNCEQQWIFESYRPGPQSGCRVLMTSRNAVWSSSNVRAIAIDLLTPAESRQMLQKLAPRVTDAEADDLAKLVGYLPLALHVMGVALGTLEPSLPVANYYQRVQQALVAELETSANTLQNLHRSPTNHQWSVVATVRVSYGLLKRSYQDEAKLRHLLLLLACCAPNAPIPIDLLVRATEQDSATVGGWLYVLRQSGFFDHDPPQLHPLMREAIRIIEAEHYPNAANIMTAALVAEGKDAHEKWQREAMLALVPHLSACHETEKTKQGYTGNVLAIIAQINQRQGNYRQAEQSMREVLEYEIAVYGYEKQEVITTQHNLANILYDQGLYIEALNLFQEILTIEQQILDAEHPHILATKHELARVLQAQGEYAQALELYQTVLASNQRVLGTDHPSTLASQHNIASVFLAQGDYIQAQELYQTVFTIQQRVLGENHPSTLAAQHELARVLVAQGNYVKAQDIFKAVLVINQRNLGTDHPHTLTTQHELARVFLMLGDYDQSLDLFQTVLVINQRVLGAEHPLTLSTQHHLASIFLAQGNYVKAQEVFQAVLPTKQQVLGAEHPDTLATQHNIASIFYSQEAYDQALDISQTVLNIEKQTLGDDHPDTLITQSNIAVCMARQGQYYEAVALFYEIIPKQIRCYGGTTHPKVQASIEIRDAIVAAFWQKEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF0</accession>
    <name>A9AYF0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-mannosidase</fullName>
            <ecNumber evidence="10">3.2.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0884"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03532">
        <property type="protein sequence ID" value="ABX03532"/>
        <property type="gene ID" value="Haur_0884"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0884"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_1_1_0"/>
    <dbReference type="OMA" id="KRQWKGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-898-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Glyco_hydro_2" evidence="7">
        <location>
            <begin position="197"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase_ig" evidence="9">
        <location>
            <begin position="665"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Ig_mannosidase" evidence="8">
        <location>
            <begin position="752"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="823" mass="92458" checksum="7F0DE64F33FB9F83" modified="2008-01-15" version="1">MQKLALQQAWQAKQRDPQRTVLADSTSSEGWIAAPVPGTIYEALIAAERIPDPFDGLNELAVQWVAEVDWLYRCDFELTAEQANQPAALHFAGLDTIATVWINGQEILNSDNMFVPQRVVVSNQIHVGANQLLIEFRSALKHGHALQAEMGQLGVWNGDPSRLYLRKAQYHYGWDWGPALLTAGPWLPVTLELGATRLSDLACPISVADDCSTAIFAVTATVADVQADTAVLIQLWNPAGELIAEHQQLVVAGNIQHSITVDQPSLWWPHGYGQQHRYRLAVKVFANQTVLDQQELQLGVRRVRLVQEPLLDEAGETFLFEINNVPMFSGGANWIPADLLTNRVSNEHYRRLLQAAVDSHMLMIRIWGGGIYEVDHFYDLCDQLGLLVWQDFMFACGMYPAHPAFLASVEAEAIAQVQRLRHHPSIVLWCGNNEDYQIAQTFNAYDHSFQGDFTKTSFPAREIYERLLPKVCASYDPTTIYWPGSPYGGADVYDKTRGDRHTWDVWHSAMAPYQDYPKYEGRFVSEFGMESCAALPTLLSVIPEHERYPQSRTVEHHNKSEGGARRLAVYLNDTLRFENTLESYVYATQLMQAEALAAAYRGWRRRWGGAGRYAVAGALVWQLNDCWPVISWAIIDSALRKKPAIYSIGRELAPISAGLQRNGATIEAWVVNGTIESKSATIQLTGYDLHGRLLFEQNIEYELAANQANPIPSPNLNLPEQSVVGMQVLVDGVVVARASAWPEPFKYLPAYDPQISVTRMADDWLEISSQHPAKGVWLQTEAEINWSDNLLDLLPNQPQRIQACGLGQQPIDIKWLHWDQART</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYF2</accession>
    <name>A9AYF2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl xylan esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0886"/>
    <dbReference type="ESTHER" id="hera2-a9ayf2">
        <property type="family name" value="Acetyl-esterase_deacetylase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03534">
        <property type="protein sequence ID" value="ABX03534"/>
        <property type="gene ID" value="Haur_0886"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0886"/>
    <dbReference type="eggNOG" id="COG3458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054209_1_0_0"/>
    <dbReference type="OMA" id="VHFAARG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-900-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="36768" checksum="FCB81FF5A5CE02AE" modified="2008-01-15" version="1">MHFDMPLEQLREYRPDRNEPADFDQFWQTTLADARQYPLNANFEPYDMGLPLIEAYDVTFNGYGGQPIKGWFLLPRNTTKPIPCVVEYIGYGGGRGLAIDWLLWPTAGYAVFAMDNRGQGSNWRTGDTPDTEIEGGNPQIPGFMTRGVLNPQNYYYRRLFTDAVRAIEAARSHPLVDAGKVALAGGSQGGGISLAAAGLQPDVAAVLPDVPFLCHYRRATTMVDTYPYAEVAQYCARHRTKIEQVFNTLDYFDGMQFAARATCPTLFSVGLMDDVCPPSTVFAAYNHYAGPKEITVWQFNRHEGGENFQTLEKLKFLTKLWGNEERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYI2</accession>
    <name>A9AYI2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0916"/>
    <dbReference type="EnsemblBacteria" id="ABX03564">
        <property type="protein sequence ID" value="ABX03564"/>
        <property type="gene ID" value="Haur_0916"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0916"/>
    <dbReference type="HOGENOM" id="CLU_1523131_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-930-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="176" mass="19457" checksum="8DF2D08E217A6AA0" modified="2008-01-15" version="1">MDGFLLANASTSNAALFEQLADLGVSLQHKATAQRPASWLWICTNQVEEADRLISFVASTPLLVVVLQPLVHTLRLGPLFGADDYCCVDCFQRYNALFPTPATSDYLMALPAWQTAARWLTNQLQQLAARILVIRADGTSQLGRLPRDPLCLRCSSFRNYPIDSLQQLHQPSANGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYP9</accession>
    <name>A9AYP9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas2</name>
        <name evidence="11" type="ordered locus">Haur_2387</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2387"/>
    <dbReference type="EnsemblBacteria" id="ABX05027">
        <property type="protein sequence ID" value="ABX05027"/>
        <property type="gene ID" value="Haur_2387"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2387"/>
    <dbReference type="eggNOG" id="COG1343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161124_3_0_0"/>
    <dbReference type="OMA" id="GKWTQYS"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34405">
        <property type="entry name" value="PTHR34405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032582">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR032582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10547" checksum="2C6FC44CF2AE2EE9" modified="2008-01-15" version="1">MFILISYDIPHDKRRSKIAKTLENFGKRVQYSVFECQLTDSQLADVRGRLTALVVPNEDSIRFYSLPKDAVTAMLILGHGVVTHDPSFYWTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR7</accession>
    <name>A9AYR7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2405"/>
    <dbReference type="EnsemblBacteria" id="ABX05045">
        <property type="protein sequence ID" value="ABX05045"/>
        <property type="gene ID" value="Haur_2405"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2405"/>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_459885_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2433-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026457">
        <property type="entry name" value="CSLREA_Nterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04214">
        <property type="entry name" value="CSLREA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732251" evidence="1">
        <location>
            <begin position="27"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="601" mass="64066" checksum="C8F2E948C3A286D3" modified="2008-01-15" version="1">MGSFVRGLLVMVSFVSLLGLMLPAQAASLQTTFVVTTADDDFIADNGTCSLREALYAANTNQAYDACPAGGANDTIQLAAANYRLTRTGMNDETGVLGDLDILSDLTITGVSSATTIIDGMESDRVLDIYTATVTLNNLQIRNGFVDNDDELGRYYGHGILQRYGNLQIQSSLIERNGLLRSTMLANNYGGGIASLNGTLSIVDSTIRSNALRSYVDGFDEGSGHGAGLYISSQAVTITNSLFDNNQRGFGPAIYMIKGNLSLLNSVIQRSSDSHQTSAAINVLGGQLRITGGGLLNNTPQGLSLRGASSATLADTTFVGNGSSDPNARECSRGGAIYNAATLSIMHSRFIGNYADLGGALYQHAGKATLLDSEWVENRSSGGVRNDEECFGYGGAIYQNLGVVTLDTSTIAHNYSFHTGSGIAQLQATAIMTITNSTIVSNTNRYYEYDPEYPDMRTAGLYATGRMSLGNTIVANNYNTSVADAYDCMGTVLSLGHNLLEHPRPQAMYQCIFQAQASDQLNLDPILDQFDFHSGTTRSYSLNPLSPAIDAGADCGPFDQRGIPRPQDGDGDLQAVCDIGAFEYSLPAPTRFMLFAPYISQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY2</accession>
    <name>COBS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="1">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cobS</name>
        <name type="ordered locus">Haur_4390</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYY2"/>
    <dbReference type="STRING" id="316274.Haur_4390"/>
    <dbReference type="EnsemblBacteria" id="ABX07022">
        <property type="protein sequence ID" value="ABX07022"/>
        <property type="gene ID" value="Haur_4390"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4390"/>
    <dbReference type="eggNOG" id="COG0368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057426_3_1_0"/>
    <dbReference type="OMA" id="FMDSMDG"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000132583" description="Adenosylcobinamide-GDP ribazoletransferase">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <sequence length="249" mass="26919" checksum="28CAC6E23E9D2567" modified="2008-01-15" version="1">MIKHLAEALRFLTILPIPGKPALSEQALVRSMVAFPLAGTLIGGLVAATWFGATWLWGTTTGSLCAILTWGAITSGLHLDGIADSADALFSWRSRERKLEIMKDSRIGTMGAIALISILLLKWLFVLGCGDLAWRALIVAPTLGRWVDIIGIFWFPPAAEGGLGRTFHDHTRRSDFWWATSCAGLVAAGLLWWWAGLIFAVVIVATIIIARWMVRSLGGLTGDTYGALCEIAEMLVLAVVAALVNHQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ94</accession>
    <name>A9AZ94_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0992"/>
    <dbReference type="EnsemblBacteria" id="ABX03640">
        <property type="protein sequence ID" value="ABX03640"/>
        <property type="gene ID" value="Haur_0992"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0992"/>
    <dbReference type="HOGENOM" id="CLU_1862424_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1008-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="15864" checksum="F19A7059A366D91D" modified="2008-01-15" version="1">MQQIQQVKYGKKPLGIMLIGFIFAARATFAGGMMLIFVLRFLDLQPGYLLPYGFMVLVSGAFTFLHIKIVQGLFGFREKMRNLAVILELIIVVLYWSSRFLFDYEPELAQTISIIISMVIIWYLSRDKTRAWFAPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZC2</accession>
    <name>A9AZC2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1020"/>
    <dbReference type="EnsemblBacteria" id="ABX03668">
        <property type="protein sequence ID" value="ABX03668"/>
        <property type="gene ID" value="Haur_1020"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1020"/>
    <dbReference type="HOGENOM" id="CLU_2259902_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1037-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="103" mass="12171" checksum="9434745B0057A7A2" modified="2008-01-15" version="1">MDSFLPFLMFVGFLGLIIAWHVFEHKRSVQLIQQWAATNGYRIIALEQRWLRRGPFFWRSGKYHTVFYVDVIDPQGMARAIWVRCGGWISGLFSDQLDVRFDS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE6</accession>
    <name>URE1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urease subunit alpha</fullName>
            <ecNumber evidence="1">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Urea amidohydrolase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ureC</name>
        <name type="ordered locus">Haur_2452</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="1">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Carboxylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZE6"/>
    <dbReference type="SMR" id="A9AZE6"/>
    <dbReference type="STRING" id="316274.Haur_2452"/>
    <dbReference type="MEROPS" id="M38.982"/>
    <dbReference type="EnsemblBacteria" id="ABX05090">
        <property type="protein sequence ID" value="ABX05090"/>
        <property type="gene ID" value="Haur_2452"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2452"/>
    <dbReference type="eggNOG" id="COG0804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000980_0_0_0"/>
    <dbReference type="OMA" id="GFDSHIH"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00375">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017950">
        <property type="entry name" value="Urease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0533">Nickel</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000188877" description="Urease subunit alpha">
        <location>
            <begin position="1"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Urease" evidence="1">
        <location>
            <begin position="131"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="1">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01953"/>
        </source>
    </evidence>
    <sequence length="569" mass="60668" checksum="F0705DF8068C7465" modified="2008-01-15" version="1">MSLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSSSAHDVLDLVITNAIIIDHWGIVKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEVIAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGGTGPATGTKATTCTPGVWNMARMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQYDVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSSTNPTRPYTVNTIAEHLDMLMVCHHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMISSDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQRVKRYIAKYTINPALAHGIAHEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFGAFGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDPETYAVRADGELLTCEPATSLPLAQRYFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV0</accession>
    <name>A9AZV0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4523"/>
    <dbReference type="EnsemblBacteria" id="ABX07154">
        <property type="protein sequence ID" value="ABX07154"/>
        <property type="gene ID" value="Haur_4523"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4523"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150624_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4578-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="241" mass="26905" checksum="12AB9C2D8E5C934F" modified="2008-01-15" version="1">MRYFSQQKLDQLLAAHAEWLQEPVGEAMSLCNCDLRGMDLRGRSLMRVQLENVVLAGCDLRDCNFFGAMLRKVDLQAADLRKACFASSFCEQIDARDSNWQQADLISAIIKLSDFSHANLAYADLNKTSFESSVLDQAILSYTHTVRFSLSRSSARNAQLDHAMLDFATIYACDLRGANLNAASLRQLKSFEHVAVAGLQAKDVVIEGGRFTGWFDASPEADGSQRHDADWMRQQLTKADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZX0</accession>
    <name>A9AZX0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RfaE bifunctional protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1029"/>
    <dbReference type="EnsemblBacteria" id="ABX03677">
        <property type="protein sequence ID" value="ABX03677"/>
        <property type="gene ID" value="Haur_1029"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1029"/>
    <dbReference type="eggNOG" id="COG2870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021150_0_1_0"/>
    <dbReference type="OMA" id="CEFANAA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1046-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02198">
        <property type="entry name" value="rfaE_dom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="34740" checksum="0FCB453802757352" modified="2008-01-15" version="1">MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVAASIAALNAEVLLGGVIGDDLAGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQMLRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAKGVLTERICQHVIQQARYYNIPVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIITRSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAAGIVVGKVGTATVDLAELSQAVTSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY4</accession>
    <name>A9AZY4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ordered locus">Haur_1043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1043"/>
    <dbReference type="EnsemblBacteria" id="ABX03691">
        <property type="protein sequence ID" value="ABX03691"/>
        <property type="gene ID" value="Haur_1043"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1043"/>
    <dbReference type="eggNOG" id="COG0061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_0_0_0"/>
    <dbReference type="OMA" id="VNLGHVG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="60"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="275" mass="29999" checksum="7518FA9598022762" modified="2008-01-15" version="1">MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGDGTVLRAARIGITYNMPILGVAMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARVLRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTSYRADGVLVSTATGSTAYALAAGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEPDDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B019</accession>
    <name>A9B019_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1078"/>
    <dbReference type="EnsemblBacteria" id="ABX03726">
        <property type="protein sequence ID" value="ABX03726"/>
        <property type="gene ID" value="Haur_1078"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1078"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_4_0"/>
    <dbReference type="OMA" id="RRESQCR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1098-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="318" mass="33858" checksum="BB9C8AD1018086FA" modified="2008-01-15" version="1">MSELWNSLKQQIAQHNWGLFGPTSYVLGVDLGSYGIRAVVTDICGQHLFHAATELAPESTATTVLEQSFSLIHELLETNNVPSQQLVRIGVGFGGPVDALRGVTRRSYRMAGWNDLNVCEQFEAAFDAQTLIENDASLIAFGEYMFGAGRDVQDLYYLHLSTGVGSGLVLNGQLHRGITTSAGEIGHARYSLNHQREIEDLLSIRGLLARANELGLQTDDLDVLFNDANAGAKTISEAVEVLGLGLAGVVQLLDPALLVLGGIVTRKGGDALCSAVETQVNQLISPTPPRHIAVVHSLLGAEAVAIGGLALALQSLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B057</accession>
    <name>A9B057_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1116"/>
    <dbReference type="EnsemblBacteria" id="ABX03764">
        <property type="protein sequence ID" value="ABX03764"/>
        <property type="gene ID" value="Haur_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1116"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018489_2_0_0"/>
    <dbReference type="OMA" id="HTDQSLD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732288" evidence="1">
        <location>
            <begin position="23"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="385"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="562" mass="61570" checksum="EABAA12A4F1CDAD7" modified="2008-01-15" version="1">MRFRFILRLLLLFIFLSACGQAANPMQPSQSGQASSDDLVLRLLYGSEKQLWIDAVVSDFNASSAKTASGQRIQVEAVPVGSLETINGLLDGSQQADLWSPASSLSLPLANQRWKTAKGELLFSDQTPTSLVLSPVVIGMWKPMAQALGYPDKQIGWADLADLATSGKTWADFGHPEWGAFQFGHTHPEFSNSGLATIVAMAYAANQKTSDLTVADLDKPETASLINAVEQSVIHYGSSTGFFAKTMYEHGPSYLSAAILYENLIIESYDQALYPNLELPMVAIYPKEGSFWSDHPLVVLETERMNADKRAAAQVFQEFLLAQPQQAKAMQYGFRPANVDISLAAPIDTAHGVDPSQLQVALPTPSAEVLQAITQLWQQHKKQVDVALIIDTSGSMRQENRLREAKTALGDFIDIFADQDNVQVTIFSTNATELSDLSPIGPKRADLHTRIDGLVADGETRLYSTIGEVYTDIQQQTEVQRIRALVVLTDGEDTASSLSLEQLNEQIRQDESGTSIKIFTIAYGSDANQEVLQRIAEITGAKSYTGDPATIRQVYHEIATFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B092</accession>
    <name>A9B092_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2563"/>
    <dbReference type="EnsemblBacteria" id="ABX05201">
        <property type="protein sequence ID" value="ABX05201"/>
        <property type="gene ID" value="Haur_2563"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2563"/>
    <dbReference type="HOGENOM" id="CLU_1394674_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2591-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="20995" checksum="BD89D36ED39ECBBD" modified="2008-01-15" version="1">MKNQRDTMMTVGTVVVVVVAIVLLIMIANIAANVVGALVPLVTGSLLLFGNRTELMSLLRTRNLGLNSLNVLIGISLVLFGAGQTLFGETFLRVLFYIPAVICLALAAPLAFGKTDTSATYRAWWNSIRSKVRRKPSTPSVINTGFEPAVNNTPPTSQAPNYNPAPSPQANFDPMTGQRTVKLDPNEINNSGVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B095</accession>
    <name>A9B095_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2566</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2566"/>
    <dbReference type="TCDB" id="9.B.160.1.9">
        <property type="family name" value="the colicin v production (cvpa) family"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05204">
        <property type="protein sequence ID" value="ABX05204"/>
        <property type="gene ID" value="Haur_2566"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2566"/>
    <dbReference type="eggNOG" id="COG1286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092720_4_4_0"/>
    <dbReference type="OMA" id="GIAGYYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2594-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="18095" checksum="C3001C348B776FBE" modified="2008-01-15" version="1">MRLTILDWVLIGILLWYSVLGFYWGTIRQLLALAGLITAIAIAGRIYPGVTDLLISLIPATAPGFISVFAFLLSLLAVTALVSAIATWLRLKVGLLFLGRADHVIGALLGLVQGIVLIGACLAGCVGLPQIGIIDAIQQSSLAEYWGPVVLVIVNLLPETFVPMNQMLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0C9</accession>
    <name>A9B0C9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2600"/>
    <dbReference type="EnsemblBacteria" id="ABX05238">
        <property type="protein sequence ID" value="ABX05238"/>
        <property type="gene ID" value="Haur_2600"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2600"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010499_0_0_0"/>
    <dbReference type="OMA" id="ANYIARW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2628-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731769" evidence="1">
        <location>
            <begin position="23"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="797" mass="87893" checksum="2122660F58B165DE" modified="2008-01-15" version="1">MSRSSKLISIVTLFLIMLSAITKPSAPVAAVEPQIPSSPGTWSQDFGLYIKTAANSYTPLRPIEWNGTLYAILNGHRNFESGVGYWNDQQWLKIDGLNGQVDVLTVHQNRLYVAGRFTIAGKNLNLAYWDGNLWTAMPMHVVQDGPFLLASYANQLYLGSEALLIDDQAYGSLARWDGEQWHAAAAGIEGVVFTMLSRPDGLYLGGSFLYNGQATSLLYWNGSQWQTVGGGVYGHVVDLKWANNQLYISGNFTSTLVPSMRNVAAWNGTNWNTFDTGLTGWVHNVTVMDGELYALHRPTDSSGYEHLHWDGSEWIFLADLGSMDYSWLFSPRAVFVQYKQELLLVGEISYYSSAVEPTSQGDSTLRWNGTEWEPMNSHGLLTRMATAIATVDENLLVASSNFYWSQGVASLAQFGSNQHWQKLVDRRSTSDPVQALEAFQQSHFMVSYYTLYEAASTTWNQIGAFRVVRAIAQSNNKLYVAGDFEQFNGVTAHNLVTWDGTQWQALNAPASFDQVVLIEAHGNHVYISDGFQLARWDGTQWTTLATNVVNIGSIEATTNGVYIAGTFSSVGGVTAPKIAYWNGTAWSGLSGVISGSILDLEMGADGLYVAGNFFGLNNGIVSPGILRWDGSAWHGVGGGVQTYRSFGIVNNGTVQRLAATPTRMFMYGDFNRVGNQYESYTLAVWEYGDEPLIKAKPDYAFTNRPQAVTVNVLANDWSYHPSQLQLVNLTAPSHGTAVISGNSVVYTPYPQFTGIDTLTYTVRDPINAVTTTAQLRLYVWNTPNVVLNELYLPAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F5</accession>
    <name>A9B0F5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4542"/>
    <dbReference type="EnsemblBacteria" id="ABX07173">
        <property type="protein sequence ID" value="ABX07173"/>
        <property type="gene ID" value="Haur_4542"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4542"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067347_1_0_0"/>
    <dbReference type="OMA" id="DGIEVYY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4597-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="29436" checksum="4F5BD8F1DE65B62F" modified="2008-01-15" version="1">MLLDLHCHTIATPHHSHWTPTELMAAAQAAGIQVIGIADHNTTSQVTAFAEAAQAAGLDFIGGVEFDSAFNGKLWHTLVYGANPNDPGILGLCEAVVRRNHADAQRLLEQTRSAGHDLPSLAQIAVDRPANLADVAHGLVRDGIWPSQTGVDPESAGMAYLLTNQPEAYNPLSVDEIVQVAHAAGGVAILAHPGREKSVYAIPATAADFVALAAIGLDGIEVYYPMHSSEQVAFFVQQAALHGFLISAGGDSHGPRDPFSPQPAARCRDLLARFGIDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0G1</accession>
    <name>A9B0G1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ordered locus">Haur_4548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4548"/>
    <dbReference type="EnsemblBacteria" id="ABX07179">
        <property type="protein sequence ID" value="ABX07179"/>
        <property type="gene ID" value="Haur_4548"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4548"/>
    <dbReference type="eggNOG" id="COG0692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_3_0_0"/>
    <dbReference type="OMA" id="PDNGYLM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="50"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="225" mass="24874" checksum="1C5FE7DC520EA80A" modified="2008-01-15" version="1">MALTIPALWQPVLADETSKPYWNDLEAFVAAERAEQQVFPPEDQVFSALELTSPEQTKVLLLGQDPYHGPGQAHGLCFSVLPGIKAPPSLKNMFKELKTDLGCVVPNNGYLLPWAKQGMLMINAVMTVRAHTANSHKNRGWEKFTDAVIRQVNAKPEHVVFVLWGAYAQKKASLIDNSRHTIIQSAHPSPLSADNGFFGSRPFSKINAALEAHGQSQIDWQIPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J0</accession>
    <name>A9B0J0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4577"/>
    <dbReference type="EnsemblBacteria" id="ABX07208">
        <property type="protein sequence ID" value="ABX07208"/>
        <property type="gene ID" value="Haur_4577"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4577"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_1_0"/>
    <dbReference type="OMA" id="MCGLIKR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4632-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18687" checksum="920E9D88C524DFDA" modified="2008-01-15" version="1">MQTIRTARLIIRRFGLADAAFIVQLVNQPSWLRWIGNRNVHTLDDAETYLSSGPLSMYERYGVGLCGVELAGKLIGMAGLIKRSPEAEIDLGYAFLPEYWGQGYATEVAQALLNYAIHMLKLPRIIATTQLENQQSIKVLERIGMQFEGIIHEGEKSLRLFGYGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0M1</accession>
    <name>A9B0M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4608"/>
    <dbReference type="EnsemblBacteria" id="ABX07239">
        <property type="protein sequence ID" value="ABX07239"/>
        <property type="gene ID" value="Haur_4608"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4608"/>
    <dbReference type="eggNOG" id="ENOG50314C3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116689_0_0_0"/>
    <dbReference type="OMA" id="TCSSKHA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4665-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="20863" checksum="7451540B2D1945D3" modified="2008-01-15" version="1">MIVGRLPDVPLDADLPISASLISQGLEHYQAVARWIATLPFGRNTNPLDWRLVLSEKRGTSSTKHAFLAELARELALPINLYFGIYLMDGKNTPGVGETLASNNLPSIPEAHCFLRYGRWNIDVTRSPKAEPILQFFEEQQINSEQIGDFKRTVHRNFLLKWATSQGLSLTKAWAIREACMAALSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T1</accession>
    <name>A9B0T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1153"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03801">
        <property type="protein sequence ID" value="ABX03801"/>
        <property type="gene ID" value="Haur_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1153"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022796_0_0_0"/>
    <dbReference type="OMA" id="HDDIGWA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1175-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047669">
        <property type="term" value="F:amylosucrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11324">
        <property type="entry name" value="AmyAc_Amylosucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044077">
        <property type="entry name" value="Amylosucrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="89"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="657" mass="74569" checksum="49D59BA1A4FC4BE2" modified="2008-01-15" version="1">MQPLTVQTMHLPNPTTFDDLLDQQIANSRDRDIFRLRMQRHFGDCLEALGALYAQHPAWPQLLEQLPERLITAYAQRRDALKIHDLAREIQPDWFAEATMVGGIYYVDRLAGTLRGVIEHIDYLQELGLTYVHLMPLLQPRHGPNDGGYAVLDYRSIDQRLGNVADFIELSDLLRTNGISLCIDVVVNHTAKEHEWAVKARAGDAQYLDYYLSFADRSLPDAYEQHLPEVFPDFAPGNFTWYAELSEHGRWVWTTFNEFQWDLNYTNPMVWLEMLDILLYLANLGVDVLRLDAVPFMWKRLGTNCQNQPEVLDLLQAWRAAMRIVCPATIFKAEAIVAPDDLVQYLGLGRRTGKLCEIAYHNSLMVLLWSALASQRADLFTQSLLNMPATPSNAAWITYVRCHDDIGWAVTDHNAALVGEDGPLHRQFLSAWYSGEFAGSFARGEVFQYNPLTNDRRISGMTASLAGLEQALETTDPAAIELTIRRIALLYAVIFSFGGIPLIYMGDELGMLNDHSYLHDPTKANDNRWLHRPAMDWCLAAQRHDPTTLAGRLWQVLRHLIQVRQHTPALHSAGQTLPIWTQQRHVLGVVRVHPLGRILILGNLSATPQRVSLAVIQQAGLVGRLYNLLDNDSLNIDTQSHEIILDAYQCCWLSIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B105</accession>
    <name>A9B105_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05283">
        <property type="protein sequence ID" value="ABX05283"/>
        <property type="gene ID" value="Haur_2645"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2645"/>
    <dbReference type="HOGENOM" id="CLU_619319_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2675-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="442" mass="48130" checksum="BD24016BBF073206" modified="2008-01-15" version="1">MEYGHCEGMAVLSILFQRGILNPADFGAARTRDLVLEGNQKLQREIAYWYATMIPNPGRAARIIAPPRDLVAVLRTAFANTQTAFYTLRFSKLDRSGGHSVVPMGLRDISANEVAIQVYDSNSPTIARELIVNTATNTWSYSPALDPNQTSDDYNGTAQSLTLGLAPIEPRQGQQTCALCAESDPLLNTTASSDNPIILPPTTTNDGMGNVNQGNADISNPEFITPWMDLAPSNPLVDSWSSPVLKYFVLQPNADGHFVLSAPSENQTNIPVSIRSIGRGYTFEVETTVASGFPSEVIVGSQGNVITFTTQTTTSPTMYLGFETPTDDFDFYIEDFDLSADDSFRLEVDASNKLVGLRAITAIPDESVTFSLSMERIDDQGIEIFNSPDEGISLFENEILLIDFSQWSGNGGTLRMGYDDNLNGLIDANEAFVIEDVGDTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B187</accession>
    <name>A9B187_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_C25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4643"/>
    <dbReference type="EnsemblBacteria" id="ABX07274">
        <property type="protein sequence ID" value="ABX07274"/>
        <property type="gene ID" value="Haur_4643"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4643"/>
    <dbReference type="eggNOG" id="COG1572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_307349_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4700-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029031">
        <property type="entry name" value="Gingipain_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038490">
        <property type="entry name" value="Gingipain_propep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732323" description="Peptidase_C25 domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="3">
        <location>
            <begin position="563"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1017" mass="113357" checksum="25302A79C8C2F8A6" modified="2008-01-15" version="1">MLQRWLIGCLVVSLMLIRQPVIAQITTATLTLQRHDQQLHINVQLPKPTLQPNSINIAGWQNDATPDQPALPRSSHWLVVPAGYQLRLKSVNPQQLQHYQQQLSLTPSSGWQVDPLAPSKAIALSAPSVAVKQAQYPTTWANLGQSVQVREQQLVPLTIFGAQWQPSKQQIVVPSSIDIALEFVASTEQPSLRADPFWNELLRQQVLNPSDLQNPALRPAFATTTPVTNGVRVSFANPGISEIRWSDLQAAGVPSQWLNQSANLQLWQGRNQLPRLLTATGMIFYLPPYNRDQSLQGSVIVRWNGQQPGNVLVSESVNSANPSLSYYSETLRLEEQKLYLSAFPASGTNRWWWQYWYSPGSGQSAQPLQINWNLDNATRFDQPARLRLRLHGGKLGNRHQAEIRLNNRLLTTVTITGFQLLESTINLPSGWLSATNQLTITPMSTERETSFLDWVELDYQRQAQAVAGQLQWSSSQANQSISNIISENPLLFDVQTPLAPRRLIGWNLQQGQLSWQTSGNRRYLVQSQRQTPLSSVWFSQPDLSSTSQQADYLLISYNPANSSSWSDALQPLITQRASQGLKPLLIDVQQIYDQFGDGRVDQQAIADFIKYAYHNWQAPAPSFVVLVGDGTADPHDYADIIGQPVTNFIPPYLADVDPWLRETAADNRYVTVAGNDTLPDLFLGRIPARSLSDVEHVVAKILSYEATPSNADWLNKLLFIADDPDVSGDFPWLSNEVVEILPPTVDDQQLYYTANTNLTNFRAEIVNQINNGQFLVNYVGHAGIDVWADPTIFNQQSVASLSNSALPLMLSLSCYAGHYQQNDLESLAEMLVLQPEHGAVGMWAASGLGIAHGHDYLNRGFVNSIINDGWRLVGPATIQGKLDLAAANISPDLLDTFSFFGDPALRLPLPTNNAWQPQADYYEVLQYSQANRLTPLANDQADFSQIISLEQPQHGQVWLDADQRSVRYTPDPVYNGLDSFNYQVRNLSLNQTLSATVTISVTAIAPQLYLPLTIADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G0</accession>
    <name>A9B1G0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4716"/>
    <dbReference type="EnsemblBacteria" id="ABX07347">
        <property type="protein sequence ID" value="ABX07347"/>
        <property type="gene ID" value="Haur_4716"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4716"/>
    <dbReference type="eggNOG" id="COG0448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_14_0_0"/>
    <dbReference type="OMA" id="QEWDVDE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4774-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732330" evidence="2">
        <location>
            <begin position="19"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="NTP_transferase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="407" mass="43983" checksum="A5482189066DEAE9" modified="2008-01-15" version="1">MRVLALIMAGGASPSLSALTAGRAAAATPFAGKYRIIDFTLSNCVNSGIYDVGVLSQHQPRSLHEHIGVGKPWDLDRLQGGVRVLHPFPTPDGGGWQRGTADAIRYHLDVIEERPVDYVMVLAGDHVYKMDYRPLLDLHMQRGADITLAVHSVPPHEAYRYGMVSVDGEGRVTKFEEKPRRTSSALASMGVYAFRKDYLVDLLYRDQAVDFGSEMLPRIVNEANVCAYTFNGYWADVGTVQAYYEANIALLAETPALDLYDPEWVVRTRSFERPAAQLGASARIERSLLCDGCRVDGHVSGSVIGTGVVVGAGAIIRDSVIMPDSVIEPGVVLDNCVVDKQVVIGRDCRIGEGSIGTPNAAQPQLLNTGLSVIGKAARISASHTIGRNVVVTARSFVDQDLASGETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G3</accession>
    <name>A9B1G3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4719"/>
    <dbReference type="EnsemblBacteria" id="ABX07350">
        <property type="protein sequence ID" value="ABX07350"/>
        <property type="gene ID" value="Haur_4719"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4719"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105789_3_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4777-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="18849" checksum="9941D7CB1FF13697" modified="2008-01-15" version="1">MSDPTLIDSMLRWHLPLMSRTLETLGHILARVSQQQATTLRDGADGWTVLEVVCHLRDYDQIFQERASSILEQDNPLFQSYNPDQLARERDYNASELHAVYAELCVSRTRYVEFFQSLSPEQWQRHGTHPKLGVFSLADALMQVTGHDLIHMEQITRILLQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T1</accession>
    <name>A9B1T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2735"/>
    <dbReference type="EnsemblBacteria" id="ABX05373">
        <property type="protein sequence ID" value="ABX05373"/>
        <property type="gene ID" value="Haur_2735"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2735"/>
    <dbReference type="HOGENOM" id="CLU_914569_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2766-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="32826" checksum="708DB19B81F0EF0C" modified="2008-01-15" version="1">MPEPIQPTTPLTPPANPEQPVATNVLQPQVTQVLDSSTQALPPNPSYGQSPQAYGYQQPTQYGQQQGYGQPQPPYGQQPAYYQQPPQAYGYQQQPVAYGNPAYMGPPPIISDINAPDRGLRWVGMNVLGFFVASMSFLSLFFGLAMVVAASYVDSNSNFENIENIANADILVLFGYGVCAALTAAIVALIQRGALHNKVSLWPWIGKTALAVGILLPLSTFLSGTVINMLEPAESNAWMFIVLATLIFGITSFGTAFVQYLEVKEVANRPMQWVITTGLTWTILGGLVLGGLFGFFAMAIEGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1V1</accession>
    <name>A9B1V1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BamHI-like type II restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2755"/>
    <dbReference type="REBASE" id="16534">
        <property type="entry name" value="HauORF2756P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05393">
        <property type="protein sequence ID" value="ABX05393"/>
        <property type="gene ID" value="Haur_2755"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2755"/>
    <dbReference type="HOGENOM" id="CLU_2954251_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2786-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011338">
        <property type="entry name" value="BamHI/BglII/BstY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004194">
        <property type="entry name" value="Restrct_endonuc_II_BamHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02923">
        <property type="entry name" value="BamHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="59" mass="6920" checksum="06A5A95FD56C3603" modified="2008-01-15" version="1">MYKYLTDRIGNYTEIEPYFDLWRSLQIRNGILMVIAIEHDSLDHTVPLIPKGTDGRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W6</accession>
    <name>A9B1W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase, PHB depolymerase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2770"/>
    <dbReference type="EnsemblBacteria" id="ABX05408">
        <property type="protein sequence ID" value="ABX05408"/>
        <property type="gene ID" value="Haur_2770"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2770"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_500360_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2801-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731797" evidence="3">
        <location>
            <begin position="24"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="544" mass="57524" checksum="9B52E7F201E301C1" modified="2008-01-15" version="1">MKRGWLIVLLLLGILASFWSPQAASAGQWITGSVTTSAGSRNYKLWVPTNYSTSTPTALVVLLHGCTQTPDDFARGTEMNNLADNQTFLVLYPEQPTSSNANRCWQWWDSQHQTRGAGEPSIIAAMVTSIQASYNVDPSRRYVAGISAGAAMSVIMGATYPDIFSAIGVVGGLEYKAATSVLNVSTAMQSGGPNPEAQGLAAYQSIGTRANLVRVMVIHGTADSVVTPINGQQVVQQWLTTNDYLDDTQRNYSVDATVDQTISGTVPNGRSYTRTIYNNATNQPIIEHWAINGMGHAWSGGSSSGSYTDPQGPKASNEFWRFFSQTSASPTPTTTPAASATSTPPSITPTNPTSTPIAPSPTPSAGQSMQFPSWGLEDGLVAQTTFGGYVLIPSMYVGDSGSTSLRGILSFDTSAIPDGATITSVNLSLAYEQSAIGTPWTGLGSLVADLNQGCLSLTCYLELSDFGTTTTASSAMSFQQTPNGLNGSANSTGLSAINKQGRTQIRLRFENLTNANSQADYVRIAGGEAMLTSNRPVLTVTYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B212</accession>
    <name>A9B212_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4731"/>
    <dbReference type="EnsemblBacteria" id="ABX07362">
        <property type="protein sequence ID" value="ABX07362"/>
        <property type="gene ID" value="Haur_4731"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4731"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_0"/>
    <dbReference type="OMA" id="NWNKQLT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4789-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07124">
        <property type="entry name" value="ALDH_PutA-P5CDH-RocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005932">
        <property type="entry name" value="RocA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01237">
        <property type="entry name" value="D1pyr5carbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="50"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="517" mass="56171" checksum="82C5396535F04E75" modified="2008-01-15" version="1">MLPEYRNEPFVDFSVKANADAMRTALSKVGDELGRTYPLLIGGEHIELADTFDSLNPAKPSQVVGSFAKATVEHANQAVEVAATTFESWRNVAAEERARYLFRAAAVMRRRKFEFMAWLVYEVSKSWAEADADVAEAIDFMEYYGRQAIKFGGPQPVVAYNGEENELRYVPLGVTVVIPPWNFALAIMVGMTTAAIAAGNTVVLKPASASPAIAAQFVRLLVEEAGLPDGVVNFVPGSGGAMGDALVDHAKTRLIAFTGSKEIGLRIFERSAKLQPGQIWLKRTILEMGGKDGIVVDETADLDAAADAIVASAFGFQGQKCSACSRAIIVDSVYSTVLKKVVDRTKKLTMGDPTDPKHHMGAVVDQKAFDKIREYIEIGKSEGRLMLGGETGDGSEGYFIPPTIIADIAPEARLSLEEIFGPVLAFIKANDWKHALEIANNTEYGLTGAVFSRSRERLEEARRDFHVGNLYFNRKCTGALVGVQPFGGFNMSGTDSKAGGPDYLLLFTQAKTITDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B297</accession>
    <name>A9B297_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4817"/>
    <dbReference type="EnsemblBacteria" id="ABX07447">
        <property type="protein sequence ID" value="ABX07447"/>
        <property type="gene ID" value="Haur_4817"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4817"/>
    <dbReference type="HOGENOM" id="CLU_1041196_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4876-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="28250" checksum="1D4BC476CCF62D27" modified="2008-01-15" version="1">MQCPQCSAAVADSSRFCTSCGATITQPAAVDKTMALPNLPPMANPVDKTQAINPTQVPTVQPNYGPPAPVQSNYGPPAPPNVYPQQGFSQPQNYGQLPPANYGQAPMGYAVPNQSGYAAIPAGNGSIPAILMIVSALAILIGAFLPMIDTDTVTESLFQVLSYADEPSSQDMNNYQAVIAILYGIPICAGLGMLMGMLAYFKRRNLWGVLNLIIAIIAFGCSGIIVLGAVASNVTNEMGSGLWLMFLSSIFLFVTSIAFLIRKKQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C5</accession>
    <name>A9B2C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03970">
        <property type="protein sequence ID" value="ABX03970"/>
        <property type="gene ID" value="Haur_1325"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1325"/>
    <dbReference type="HOGENOM" id="CLU_1710765_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1346-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="17173" checksum="70AD83B606435F6C" modified="2008-01-15" version="1">MQAFDIANAGNFLDGGMNAVRIAMNAAKAGKTYACIQYFHNETVTYCIPESSESVEHLIALVDTMVVADPGIKTAMVMNPQSHMLWMVDRNTHHGYLMEESILQLCAGYICWECGHGQATPFNRCLMCTMDNTCQPSPLRWVHTYRDDRAAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K7</accession>
    <name>A9B2K7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endoglucanase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2820"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05458">
        <property type="protein sequence ID" value="ABX05458"/>
        <property type="gene ID" value="Haur_2820"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2820"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026903_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2851-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731822" description="Endoglucanase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="6">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="633" mass="69860" checksum="DD533185C117158C" modified="2008-01-15" version="1">MSQKQRSFRTRLAMIGGLVTLLLAGQPATTKPTAAAAICEVTYTISNQWSTGFTANVSVKNLGIGLNNWQVGWTFAGNQAITNLWNGVLTQTGAQVSVSNPAWAASLPSNGTASFGFQASYTGSNAIPNAFTLNGVSCNGDQPSPMPTNTAIPSIPPATNTPNPPTNTPIATTTGTPRPTNTPTSVIPTVTNTPRPTNTPVPTTVNPTATSTPTGNNNNDDWLHTNGNQIVDSAGRPVWLTGVNWFGFNATERVFHGLWSANLTSMMQSISQRGLNIIRVPISTELILEWKAGVFKTPNVNTYANPELEGLTSLQIFDRFVMLSKQFGIKVMIDVHSAEADNSGHYAPLWYKGSFTSEQFYQAWEWITDRYKNDDTVIAMDIKNEPHGTAHDNQTSSQFAKWDNSTDINNWKYVCETASKRILAINPNVLVLCEGNEVYPKAGASYTSSNKNDYYFTWWGGNLRGVRDYPVNLGSNQDQLVYSPHDYGPLVFNQSWFYPGFTKETLYNDVWYPNWFFIHEENIAPLFIGEWGGFLDGGANEQWMKALRDLIKEHYLHHTFWVLNPNSGDTGGLLGYDWATWDEAKYALLKPALWADRNGKFVSLDHQIPLGGTATGTTITQYYQQGNQAPSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S0</accession>
    <name>A9B2S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2883"/>
    <dbReference type="EnsemblBacteria" id="ABX05521">
        <property type="protein sequence ID" value="ABX05521"/>
        <property type="gene ID" value="Haur_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2883"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_1_0"/>
    <dbReference type="OMA" id="SHRVPWK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2914-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="348" mass="38944" checksum="9DBA52EDD9D4C31D" modified="2008-01-15" version="1">MTRQKVLVTGGAGFLGINLLRYLDAKGYDLVSYDFADWTYTDLKDHITIVKDDIRNVAGLDRAMQGVDFVVHTAAALPLYPAEDIFSTDIDGTRNVLEVAKKHGVKRVVHISSTAVYGIPDHHPLVENDRLDGVGPYGKAKVMAEYVALEYRAKGMEVPIIRPKSFIGPERLGVFALLYDWAIDGHNFPMIGNGKNRYQLLDVEDLCDAIYLSMTLPAEVANDTFNMGAKEFATMKEDYQAVLDYAGHGKKIIGSPATPAIWTLRALEFLRVSPLYKWVYETASKDSFVSIEKAETQLGWKPKFSNQDALIRNFKWYIDNRNSFANASGVTHRVPWKQGAIGLLKKAF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Z9</accession>
    <name>FMT_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fmt</name>
        <name type="ordered locus">Haur_4832</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B2Z9"/>
    <dbReference type="SMR" id="A9B2Z9"/>
    <dbReference type="STRING" id="316274.Haur_4832"/>
    <dbReference type="EnsemblBacteria" id="ABX07462">
        <property type="protein sequence ID" value="ABX07462"/>
        <property type="gene ID" value="Haur_4832"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4832"/>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033347_2_0_0"/>
    <dbReference type="OMA" id="CCPVVAY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037022">
        <property type="entry name" value="Formyl_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000118483" description="Methionyl-tRNA formyltransferase">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <sequence length="306" mass="32837" checksum="2B7A9B2AA8FA96D0" modified="2008-01-15" version="1">MRILYLGTPEIAVAPLELLHASGHEIVGVVTQPDRPAGRKNVLTAPPVKLAAERLGIPVFQPETLKDPAAVARLRAFEPEVGVVAAYGEILRKQVLAIPALGYLNIHPSILPLYRGPAPVTGAILAGDDLVGVSIIKLTAKMDAGPILGQMVMPLANDARAGEWTAQLMRQGGELLAQVLPAYAAGQIQAQIQDDSQASYTQMISKNDGLINWNLPALVIERMTRAYDPWPGTAVKLNDQPFKILRAKAHTSWSGTIQPGTLFEQQGQILVATGSGALELLEVQPAGKRPMAANDWRRGAKDIEQL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B302</accession>
    <name>PUR7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="1">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purC</name>
        <name type="ordered locus">Haur_4835</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B302"/>
    <dbReference type="SMR" id="A9B302"/>
    <dbReference type="STRING" id="316274.Haur_4835"/>
    <dbReference type="EnsemblBacteria" id="ABX07465">
        <property type="protein sequence ID" value="ABX07465"/>
        <property type="gene ID" value="Haur_4835"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4835"/>
    <dbReference type="eggNOG" id="COG0152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061495_1_1_0"/>
    <dbReference type="OMA" id="EFCYKND"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000095988" description="Phosphoribosylaminoimidazole-succinocarboxamide synthase">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <sequence length="247" mass="28041" checksum="CE825156653D53EA" modified="2008-01-15" version="1">MQYGTKLAEGKTKIIYAHPEDQSLAYMVQKDSISAGDGARRNEIDGKGAISGRTSANVFALLNRSGVRTHYQSDPEPGVMLVERCEMLPLEVVMRRLATGSYCRRHPETPEGTRFSPPLVEFFYKDDANHDPQIYLEGIVEKGLATAEEVSFIEQEGTRVFELLEQTWAERGVQLVDLKIEFGRTADGSLIVADMIDNDSWRLWPDGDKSKMLDKQIYRNLQTVTEEALQNLKAKYEEVRDITESFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B317</accession>
    <name>A9B317_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4850"/>
    <dbReference type="EnsemblBacteria" id="ABX07480">
        <property type="protein sequence ID" value="ABX07480"/>
        <property type="gene ID" value="Haur_4850"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4850"/>
    <dbReference type="eggNOG" id="ENOG5033M2W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_986543_0_0_0"/>
    <dbReference type="OMA" id="VIWEYGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4910-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043715">
        <property type="entry name" value="DUF5656"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18900">
        <property type="entry name" value="DUF5656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="31121" checksum="B6F6B5C08976BFC7" modified="2008-01-15" version="1">MKLTPRFDRILPLISLVVLGLMVVFLLESNPDYPLVARISNDLPVISVAWFIIALLVIIISTGADLLAKAHPALEHRELLRLPGPLSKIEIVPLFWVLPSAVVVGSFAFFRLFQETLQGTAFILVLVVCGSLLTATLVAQHYVLDRDTEVRDKARVGLQAVAYLVAFGMFSAIANAHYRMIFTGILAFSASVPLAYRLLARNVNDHQRPLSLALTVVGVVIAEAAAMLSFWPAPFLIVGTLLTALFYVMMNLLHHAQAGTLDRRIGWELGIVGAAVFVILTATTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B320</accession>
    <name>A9B320_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4853"/>
    <dbReference type="EnsemblBacteria" id="ABX07483">
        <property type="protein sequence ID" value="ABX07483"/>
        <property type="gene ID" value="Haur_4853"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4853"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112038_0_0_0"/>
    <dbReference type="OMA" id="YMIGIED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4913-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039248">
        <property type="entry name" value="Ptase_RsbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35801">
        <property type="entry name" value="PTHR35801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="21066" checksum="940790D5B1C86546" modified="2008-01-15" version="1">MRLNWSAQTRSKYGQSVSGDGYAVIESQNSILIAVIDGLGGGAEAAKPTKLALEELHQHATRPLKELIERCHKALHGTRGAVIGLLRLEFDHLRASYIGVGNIGIHVISDRVIKPISKNGILGHNQLPSLLEMTYTFNLGDIFVLYSDGISTRMITDSALHHAIENPEALAISLMERYGKTTDDVTILIAQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B326</accession>
    <name>A9B326_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4859"/>
    <dbReference type="EnsemblBacteria" id="ABX07489">
        <property type="protein sequence ID" value="ABX07489"/>
        <property type="gene ID" value="Haur_4859"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4859"/>
    <dbReference type="HOGENOM" id="CLU_1608597_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4919-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18823" checksum="5E011ED03BB7D85E" modified="2008-01-15" version="1">MAKLNWHDQRPLILLDIDGVINMFGRLGREQQQIPPGIPVQYPPQIHASIARLAKIGQLIWCSTWLQLANTGLHSDLGLPELPLIEPLPENPTAILWKLNSVAKHLADWQTPIFWIEDGFRPQVHTWAQQRSKQGRFTQLIDVRETGLVPQVVDQLERTLAHFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B394</accession>
    <name>A9B394_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1413"/>
    <dbReference type="EnsemblBacteria" id="ABX04057">
        <property type="protein sequence ID" value="ABX04057"/>
        <property type="gene ID" value="Haur_1413"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1413"/>
    <dbReference type="eggNOG" id="COG2268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_373299_0_0_0"/>
    <dbReference type="OMA" id="RDNIRAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1435-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="PTHR13806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="6">
        <location>
            <begin position="39"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="276"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="744" mass="81949" checksum="AF663F27FB3D1392" modified="2008-01-15" version="1">MEQIAVLVGITLLVVILLVVVFFALVNHFYVKAPADRTYVRTGGSKPKVVFNGGSWVIPAFHEITWVDLRTMDIDVERTEANALLTIDPQYADIRAIFFIKVNPIAEDIERAARTIGGKEVNTDSVKRLVESKLEGALRDVAATFTLMSLHQEREKFVERVQNLVRSDLAENGLVLEAVSITTLKSARQGSFGTDDVFGAQVARANAEVIQQALKQRNEIDQMTQTEIAKRNATAEQERNTIERQKQLEIARRNASTSQEQNDIERSSELEITRRNADVDQEKLNLERNLSQARATQQREILIRESEERTAAERVAYEQQQAAELSRVEKERTIAEAEKLKEQAVMLAEQRKQQAIQLAEQERQREVQRSQVLREQAVQVADRERQVALAQEQAKLEQAEKERLAIAAEREVAEQGVVTVQERAAAEREAQIQIINAERDAKREIINRKNEVELETFRQIKQAEADAEALNKKATAEASAAIKMAEARRTEAQAMSDAEILRAEATKATVASQGLAEAEVIKAKADAARVEAEAIRERGLAEAEAARAKALAEAEGQKALAEALAAHAGVAQELELERIRMHAQVEIGVAQAKAMGEAMAAMDFKLYGTPETAQQILRMIGLADGVGSLINTAPAPLKELGNRLINRVLPANGNGDAEKSASNDNGLNLTAAQPVLREAALIASQYLSADELQTLTVGAALEQVLGVASEEQQAVLHKVQGMLQLMPQLADQPLSSVLMLVQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A7</accession>
    <name>A9B3A7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1426"/>
    <dbReference type="EnsemblBacteria" id="ABX04070">
        <property type="protein sequence ID" value="ABX04070"/>
        <property type="gene ID" value="Haur_1426"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1426"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049717_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1448-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="34433" checksum="51858984B4B95EE5" modified="2008-01-15" version="1">MSSLQVIFGTGPAGSTLAEELISQGQRVRCINRSGKADLPAAVEVVAGDLLNQGQVNELCQGAKVVYHCANVHYAEQTKIMPQFQQTIMQASAAAGARLVVLDTLYVYGSSQGRPMTEATPFAPHTRKGRMRADLVETYLAAHRAGTLEVTLGRAADFFGPRVLNSSLGDRVFPMLLQHKPAQLLGNIDLPHSFSYIGDVARGLALLGQHPAALGQAWHLPVMPALTQRAMLQTIGTLLDYPVRSIALPKMAIQAFGLMDSFMREFVEMFYQYTEPQIVDAQAIERQLGLAATPLEQALQTTINWYRGQNQQKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F5</accession>
    <name>A9B3F5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1474"/>
    <dbReference type="EnsemblBacteria" id="ABX04118">
        <property type="protein sequence ID" value="ABX04118"/>
        <property type="gene ID" value="Haur_1474"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1474"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_10_0"/>
    <dbReference type="OMA" id="RCANTQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1496-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="144"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="38814" checksum="08ADC371EA2C889C" modified="2008-01-15" version="1">MNNPATILIIDDLAVARASMNAVLQGEGYHLVFAENGLSGIAQALELLPDTILLDVMMPDMDGFEVCRQIRANPLLAEIPVVMVTALDDRESRLQGLRAGADDFLSKPIDSLELKTRLQTITRLNRYRRLQDERRQVERLNQEIIDAYNAGIEAWSRALDLRDKETEGHSKRVTEMTVRIAEALGITGDDLTQIWRGALLHDIGKMGIPDAILHKPGPLTAEEWVIMQKHPTYAYELLRPIHYLEPALDIPYCHHEKWDGSGYPRGLQGEEIPLAARIFALADVWDALRSDRPYRAGWPVEQIREHIAGLAGSHFDPALVPLFLQLVEEAPQPVLLQHYAPATLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R0</accession>
    <name>A9B3R0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2994"/>
    <dbReference type="EnsemblBacteria" id="ABX05632">
        <property type="protein sequence ID" value="ABX05632"/>
        <property type="gene ID" value="Haur_2994"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2994"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_8_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3026-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="98" mass="10962" checksum="32FF7405EE125EB5" modified="2008-01-15" version="1">MTAALPTEIQAFLRALGNETRQTILFLFANHQQLTVGEIAELAQIGQSTASEHLTMLKRAGLLISTRQGKEVIYQADTQRMVAYAEELVVYLKTCTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R7</accession>
    <name>A9B3R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YbbR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3417"/>
    <dbReference type="EnsemblBacteria" id="ABX06053">
        <property type="protein sequence ID" value="ABX06053"/>
        <property type="gene ID" value="Haur_3417"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3417"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039811_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3454-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012505">
        <property type="entry name" value="YbbR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07949">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="459" mass="48725" checksum="ECEBFE2AA11EF285" modified="2008-01-15" version="1">MNKLAGSPLRAFVAAVLASIIWVFVSFTENPQQVTPFTNLPIRAEGLSSNLTLVDGEGRPIPVPDAVVNLNVSGPQDTITRITKQNVQPFINIAGLEPGSHEVAVQARSIPSRSDLDFQSFQPATVLVQIEQIITASLPLTITTVGQPPTSYEASLPIASVNGEMIKQVTITGPASQVNKVVGGEITLDLSSQTSNLRTRRNIIAVDIAGRDVEGVTVSPELADIEVRILSSSGIKRVPIIYTTLNSPPAGYRAEVVLEPAFVTLIGSAQRLTEVEFVETQPLNLPNSTQSYTATIKLRFPIGVTPRDAQAADSTIATIRFVPISTEIVLNLPLVPRNLPAGLELSYQPKQLEVTLRGNAQNLQNLNNLALVLDLAGRNAGSHSIQPSLNLPTGITLAKPLTTISVTLSAIIVPTAEPTSPIEPTEPATTPIATPTVTEPISPTEPISPTEPISPTLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X6</accession>
    <name>A9B3X6_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
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    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3476"/>
    <dbReference type="EnsemblBacteria" id="ABX06112">
        <property type="protein sequence ID" value="ABX06112"/>
        <property type="gene ID" value="Haur_3476"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3476"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_5_1_0"/>
    <dbReference type="OMA" id="WVIIEAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3513-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="1">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="22182" checksum="B250700ABAB49E61" modified="2008-01-15" version="1">MRAAVLTGFLGTGKTTLLLAVANALADRGEYVAIIENERGSVGIDGRYLQSQGMTVRELRAGCVCCDLALPLQITVQRLSEHYEPDWLLLEASGIAKPELLKASLQHPMISQINWRFIALVDPVRFGKMWHDSYGLGQLLRGQINIADVIVLPKSDLVEPSVLEHVAAEIRSLRPDVPVIPFTADDPAATTLMVRAFSEPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B467</accession>
    <name>A9B467_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4970"/>
    <dbReference type="EnsemblBacteria" id="ABX07600">
        <property type="protein sequence ID" value="ABX07600"/>
        <property type="gene ID" value="Haur_4970"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4970"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068892_1_1_0"/>
    <dbReference type="OMA" id="PIGYPGI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5033-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="47"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33247" checksum="DB87A759124E07F7" modified="2008-01-15" version="1">MQLDLLERLQQWHNPVLDRLFLWITNIGGEDFYLLLGPLIFWCVGINLGVRLLVMLLGSFYTNAWLKDWFDTARPAAEYPERFVLSEGAKATALEDDGSWSPSFPSGHAQHTLVFWAFVGLWLRQRWAWAIAGIMILLVSFSRLYLGVHWPIDLLGGWFFGSLIVVASIYLTPIISNLPSKQQERLALAVAAISLIGLLVDPGADRVKMLGFLAGSLGTLGLQQRYAQFQVQTVWWRQLIKIVLGISIVFVLRALLKSILPETLIADGIRYLIIGVWTTFGAPLLFRLTIAKPAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B476</accession>
    <name>A9B476_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4979"/>
    <dbReference type="EnsemblBacteria" id="ABX07609">
        <property type="protein sequence ID" value="ABX07609"/>
        <property type="gene ID" value="Haur_4979"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4979"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131367_1_0_0"/>
    <dbReference type="OMA" id="GQWIVED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5042-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17474" checksum="56995AC06983FE65" modified="2008-01-15" version="1">MGQSITSATLDFVILLLRISVIFFLYFFLYQVVRVIRRELQVVGTGTGGAGVLAGAAQNLYGKLIVMSSGDTGLQRGYAFELGAVNMIGRRPDSDVALNDSFLSSEHALLEWRGDSWWLEDQRSTNGTFINDIEVADPTPIVYGDIIRIGRIELKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C7</accession>
    <name>A9B4C7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Catalase</fullName>
            <ecNumber evidence="12">1.11.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_0032</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0032"/>
    <dbReference type="PeroxiBase" id="5539">
        <property type="entry name" value="HaurKat01"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02684">
        <property type="protein sequence ID" value="ABX02684"/>
        <property type="gene ID" value="Haur_0032"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0032"/>
    <dbReference type="eggNOG" id="COG0753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_2_0_0"/>
    <dbReference type="OMA" id="WTCYVQV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-32-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX02684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="485" mass="54471" checksum="EF25B5CF9C6BBEF7" modified="2008-01-15" version="1">MDEQEQLTTAHGAPIADNQNSLTAGPRGPLLMQDYQLLEKMATFNRERVPERVVHAKGSGAFGTFTVTNDVTAYTKASIFGAVGKQTPMLLRFSTVAGEHGAADAERDVRGFAVKFYTDEGNWDLVGNNTPVFFVRDPYKFSDFIHTQKRDPKTNMRSPQAMWDFWSLSPESLHQVTILFSDRGLPISYRFVHGFGSHTYSFINAQGERFWIKFHFRCQQGIKNWTNAEAAEVVGVDRESSQRDLFDAIERGEYPSWKLCVQVMPEADAETYHLNPFDLTKVWPHGDYPLIEVGTMELNRNPENYFAEIEQAAFEPSNIVPGIGFSPDKMLQARIMSYADAHRYRIGVNYAALPVNKPHSPVNTYHRDGQMRFDGNGGGSVNYEPNSFGGPVQNERYAEPALKISGDADRYNHRDGNDDYTQPGNLFRLMNADQQQQLFNNIAAAMQGVPEFIQLRQIGHFLKADPAYGRGVAAALGLDISSLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E8</accession>
    <name>A9B4E8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0053"/>
    <dbReference type="EnsemblBacteria" id="ABX02705">
        <property type="protein sequence ID" value="ABX02705"/>
        <property type="gene ID" value="Haur_0053"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0053"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_756002_0_0_0"/>
    <dbReference type="OMA" id="KRDYNTI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-53-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="40309" checksum="155002BBE451F579" modified="2008-01-15" version="1">MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQALQAWHRSSYSPLIVAGASSALAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWPRHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQSQLLRLQQTLTQATDTLGIAPITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRPAYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIPAAGCTYFPKIMLDQTQIDHVAQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQTILPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4L1</accession>
    <name>A9B4L1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1532"/>
    <dbReference type="EnsemblBacteria" id="ABX04176">
        <property type="protein sequence ID" value="ABX04176"/>
        <property type="gene ID" value="Haur_1532"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1532"/>
    <dbReference type="HOGENOM" id="CLU_1303475_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1556-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="211" mass="23633" checksum="1E27B70C9A1EAE44" modified="2008-01-15" version="1">MNTPLPTASHEIMRQRLVEYAHAVALGAPLDAALQVVADHVETCASCRAELFDALDASYALYSNSLSLVDNIPAPSLKFLRQHSLITSAAPETVGYRFMIEFSDEMLKHMQIQLQYTGQMRGQRLIGTYRQSSVSIPDVTIEMYESMQPKHAVLHCYIQVPERDPFDQAGTQVMVVSPTYENNGTTDADGFVLFDRIPIEELARLKIKILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T4</accession>
    <name>A9B4T4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulator, Fur family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3019"/>
    <dbReference type="EnsemblBacteria" id="ABX05657">
        <property type="protein sequence ID" value="ABX05657"/>
        <property type="gene ID" value="Haur_3019"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3019"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_4_2_0"/>
    <dbReference type="OMA" id="PHYHIIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3051-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="144" mass="16007" checksum="E9AA4D32D4A31606" modified="2008-01-15" version="1">MAIMQPEERARRLLRELEHHGYRPTPQREAVCWALARHGGHPTAAEIVEVVKQHGIGQATVYNTITTLEKLGVIQSMPLNTDEHTRYDLDTTPHMNFVCSQCGAIIDCHAPQLDLMLAQIASTAGATFEAANVVVYGRCERCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X9</accession>
    <name>A9B4X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05702">
        <property type="protein sequence ID" value="ABX05702"/>
        <property type="gene ID" value="Haur_3064"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3064"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_4_0_0"/>
    <dbReference type="OMA" id="PNPYFFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3096-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="27811" checksum="A6EA6C3608F570A0" modified="2008-01-15" version="1">MPIRGCLIDLDGTIYSAGTLIEGAVAAIEQLRAAGYQLLFLTNTDSQLPETLAAKLQARQIPIQAHEIMNPLQAIATYLANTDPNLYILAPRTVKTWLEQQYPPKADQPVSHVVLAHCGEVDGYASLNVAFRHLLQGAEFLVSQPGRNYLSNTGLNLDTGAFAALLEYASQIAPTILGKPTKTFFEQAMQALNLSADEVVVVGDDLTTDIVGAANSGMASVWLRTGKGQDQTLIPSMAQPTWVLASIAELPALLAEVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y0</accession>
    <name>A9B4Y0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Haur_3065</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3065"/>
    <dbReference type="EnsemblBacteria" id="ABX05703">
        <property type="protein sequence ID" value="ABX05703"/>
        <property type="gene ID" value="Haur_3065"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3065"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086979_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3097-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX05703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="26450" checksum="49B010DAB354710E" modified="2008-01-15" version="1">MQIDMNDFVMRLVAIVLGVTIHEFSHAFVALRLGDPTAAQEGRVSLNPVVHFDPLGAFMMFFVMLGYAPMAWGRPVPINVFRIRWGRRGFALSSLAGPTSNLLLASIFAIPLYINGGMWLSEQLYTFLYYVIITNIGLAAFNMLPLPPLDGFNTFAGLLPQGWATPMERLRRPANIILMILILLPWMINRLNLGQLDLDPRILDAMIAPIFQLFQRIVLPVAGCCHAVGHNHDHAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B506</accession>
    <name>A9B506_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3091"/>
    <dbReference type="EnsemblBacteria" id="ABX05729">
        <property type="protein sequence ID" value="ABX05729"/>
        <property type="gene ID" value="Haur_3091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3091"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753997_0_0_0"/>
    <dbReference type="OMA" id="YMYAQRT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3123-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="20"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="41084" checksum="38659E08605C398C" modified="2008-01-15" version="1">MSVGLWQTPEPTAQPQLVQTLVIGAGLIGSYLALQSQADVVLDARHVAGGASGRNGGLLLTGIANSYQAACAEYGRDLAQSLWRTTIRNRELMIEWATKLGSPVRRCGSLIFAYSEQEHAELAHAAALMHEDGFSTEWHAEDPTKRGFWGALHNPDDGAIQAALLTAALLRESGAQLYEASEVYALESTADGVLVRSRTGNWLAQRVLVATNAWTGLLLPEFSQLVIPARGQLLATAPIEPILSQACYCDYGFTYFQQTPAGNLVLGGFRNRAVAEEQTFADCTTPLIQDLLDGFLQRHFPEAAAAPIERRWAGTMGFAPDHRPLVGRLRRDDRIAFAVGFSGHGLGLGLVAADELLAELAGTPAALFSARRFSETAHLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B551</accession>
    <name>A9B551_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06188">
        <property type="protein sequence ID" value="ABX06188"/>
        <property type="gene ID" value="Haur_3552"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3552"/>
    <dbReference type="HOGENOM" id="CLU_2316449_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3589-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="10683" checksum="223B2849C765A98B" modified="2008-01-15" version="1">MQPKRLLPAFAAKITSSASLIKLALVFLNGSNTKQILQLLSPKLLKQAQKANDRAVMMPQLAQTSARAAHADCVQSPVSFVEIGQKVNATNLIQALQMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B569</accession>
    <name>A9B569_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3570"/>
    <dbReference type="EnsemblBacteria" id="ABX06206">
        <property type="protein sequence ID" value="ABX06206"/>
        <property type="gene ID" value="Haur_3570"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3570"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_92_13_0"/>
    <dbReference type="OMA" id="VEIYDRW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3607-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="354"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="376"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="571" mass="63228" checksum="F1B45B54ECB07B3F" modified="2008-01-15" version="1">MTSQTVVQNSAFELEQVLVVIERADAIASSMTLDPLLDRMLALLIEIAGGEAGTLYLVDDDEIVFQVVHGDPASQHLVGMRLPINIGLVGATIRAAQPLWIEDINADPRWDRRLGEANSLQLRSLLSLPLLLEEQVVGVIQIFNPQRSEPRLLKLLGNRMAAEVEKARLLKKSQQRESRLSALVEIVGHIGSTLDRTTLLNLIIDYARILLDAEASSLFLTEPESGDLILQHSTGHLHERVQSVRLAKGRGIAGYVAETGETICVGDVKRDQRHDGSVDQMTGFETRSILAVPLRTRCITFGRERAQSEEHLIGCIEVLNKRDGRFDDDDKLLLQTLARQAATVLEIADLYADVNELFLDVIQALTAAIDAKDPYTEGHSKRVSEFAVAIAEELELEPSFIHHLRIGAILHDVGKIGISDGVLKKPGRLTDDEFGEMKSHPEIGERILGHIRMLQTELPVIIQHHERLDGSGYPYGLAKGQISLGGRIVAVADAFDAMTSDRPYRRGLPTEEAFRRLRAGADTEFDAVCVEALWQALNRGRVRPQRLRDDIGDHRIINDATPFRTPLTPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B570</accession>
    <name>A9B570_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3571"/>
    <dbReference type="EnsemblBacteria" id="ABX06207">
        <property type="protein sequence ID" value="ABX06207"/>
        <property type="gene ID" value="Haur_3571"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3571"/>
    <dbReference type="eggNOG" id="COG1625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037396_0_0_0"/>
    <dbReference type="OMA" id="CFIDQQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3608-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007549">
        <property type="entry name" value="DUF512"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045375">
        <property type="entry name" value="Put_radical_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04459">
        <property type="entry name" value="DUF512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19238">
        <property type="entry name" value="Radical_SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="58443" checksum="EEEA0A99A2D6B1E3" modified="2008-01-15" version="1">MEYQPNLSNIRPGNGGVIQAVAAGSTGAQLGLQAGDAILQVNGRVMRDVIDFRFAMTEDQVELLVRQAGEERSIQLTKNPDDMLGLDFVEPLFDRLRTCNNKCPFCFLTQMPKGFRKTLYLKDDDYRLSFLYGNFVTLTNLKEEDWDRIAEQRLGPMYISVHATDRTLRAILLGKPDVPDVLEQIRRLGDLGIDVHTQVVACPQLNDGPALAQTIHELGQLYPIVQSIAIVPVGLTRYRFEGKKPQSIKAAIRVHESAEWIDSNWEAQPIWQEEAPVANELFQAAKEGNLGFCARLGAATEVELRPYRGDEAAAVIDICEPFQEYYMAEHGSVLVYPSDEFYLLAGREQPDGSLYEGYDQLENGVGLVRQFQDEWAEIVPSLPSAVDKPTRMLLACATLAAPVLQQVAEQLSRIENLTVELCPVVNQFFGEMVTVSGLLTGGDVVAELQKHGPADIVMLPKVMFDHSGTRTIDEWTVEQIATALGAQVTMARMPHEIRRVVRQLSRQAKPRSQRRYLAQASMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B598</accession>
    <name>A9B598_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3599"/>
    <dbReference type="EnsemblBacteria" id="ABX06235">
        <property type="protein sequence ID" value="ABX06235"/>
        <property type="gene ID" value="Haur_3599"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3599"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_0"/>
    <dbReference type="OMA" id="DDTPCHR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3638-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006522006" description="Peptidyl-prolyl cis-trans isomerase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="84"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="237" mass="24889" checksum="7BACBCCF48870C1E" modified="2008-01-15" version="1">MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNTSSPGMPKQYASEPAMTIDVNKQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYDNVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSNLLFDKAGVLAMANAGPNTNGSQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C3</accession>
    <name>A9B5C3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-1,6-glucosidase, pullulanase-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0096</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0096"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02748">
        <property type="protein sequence ID" value="ABX02748"/>
        <property type="gene ID" value="Haur_0096"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0096"/>
    <dbReference type="eggNOG" id="COG1523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004744_5_1_0"/>
    <dbReference type="OMA" id="DKIVPWY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-97-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051060">
        <property type="term" value="F:pullulanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011839">
        <property type="entry name" value="Pullul_strch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024561">
        <property type="entry name" value="Pullul_strch_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040671">
        <property type="entry name" value="Pullulanase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045041">
        <property type="entry name" value="Pullulanase_PULA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43631">
        <property type="entry name" value="PTHR43631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11852">
        <property type="entry name" value="DUF3372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17967">
        <property type="entry name" value="Pullulanase_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02103">
        <property type="entry name" value="pullul_strch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pullulanase_N2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="CBM_48" evidence="3">
        <location>
            <begin position="142"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="342"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3372" evidence="4">
        <location>
            <begin position="726"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="891" mass="99250" checksum="00A0CF53F8277673" modified="2008-01-15" version="1">MLDQSVVEEQPSVGQLDRLRAYWVRRDTIVWNIHALPNARYELHYSLDGSLELTPQGIQHGTVLPLERDPLGLDSTLAAAFPHLQGLPVLRLAPEHHDLVATILRGQVAVQAYHADDQSLIDATALQIPGVLDDLYHYTGELGVSFDEQKRPILRLWAPTARSVSLLLYADSAKGTRAIRSGMMFDPQTGVWSIVGKPSWKNQFYRFLVDVFVPSTGQFEQNSVTDPYSLSLSTNSQHSQIVDLQSQRLKPKGWSKLAKPSLTQPTDIVLYELHVRDFSITDSSVSAELRGTYKAFSQVESNGMQHLQRLAKAGVSHVHLLPVFDIATIEEHRPDRTRIDFDYLASLPADSTEQQAYLFPIRDRDGFNWGYDPRHYTTPEGSYSTDPDGSTRIYEFREMVQALNQIGLRVVMDVVYNHTHSSGQASCAVLDRIVPGYYHRLDADGNVCNSTCCANTASEQHMMEKLMLDSLRTWAVDYKVDGFRFDLMGHHLKRNMLAIRAMLDSLTLAEHGVDGKAIYVYGEGWNFGEVADGARGENASQYAMAGTGIGTFSDRLRDAARGGGPFVGFQVQGFATGLLDRPNVYEQRAFVERHYQVAVLSDVVRLSLAGNLAEYPILSCEGQQTLGGHLYINGKPAAYGLRPDDHIAYVSAHDNETLFDGVQVKAPLESPIAERVRMHNLALSLVALAQGIPFFHAGDELLRSKSLDRNSYNSSDWFNRIDWTGQQNTWGSGLPPSADNHEHWATVGPLLANPALKPTPEDMAFSYAHFQTMLQIRRSSGLFRLNSAELIKQKVWFPNTGPDQVVGLVLMVLDDGVGEQCDQQFSRIVVAFNGSHHDLSYSDASFGHYNLQLHPLLANGYDPVLAQASFDRNLGSISVPGFSCVVWVEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I8</accession>
    <name>A9B5I8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Big_10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0161"/>
    <dbReference type="EnsemblBacteria" id="ABX02813">
        <property type="protein sequence ID" value="ABX02813"/>
        <property type="gene ID" value="Haur_0161"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0161"/>
    <dbReference type="eggNOG" id="COG2373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_244681_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-164-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041280">
        <property type="entry name" value="Big_10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17964">
        <property type="entry name" value="Big_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Big_10" evidence="2">
        <location>
            <begin position="61"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1591" mass="173369" checksum="E5CC98DE86307CC2" modified="2008-01-15" version="1">MRLLEKLARWWWRWLLTTISLLGTALLGVIVASIAGWVPQPSVLRLTPLAGSRELPPATALEFNFNLPMDRSSVEDALVITPPVRGRWHWEGRARARWQPEFGWTPGTTVTVQLRPTAQSMLRQTLATTVTTQFTAAPAPLLVFRSPLPNAIIAPNTPILLRFNRAMIDYASQTERGLAELSIEPNAASQVRWLDDRSVLVQAQWQIGQHYQLKLQDLNDLLGIPVQTTEWQVQVSEPNLIAPPTTQTLQADQALEWAFEGLLDQTTTQQLIKRIQFTPAVSTTWQVQYQPDPQPQTIIQALPEAAWPAQTLTTSLQLSQPITQVWQIQPNLQLIGSVPGRGGSLAVDDPLRLLFNQTPERQQLVEQLFIEPEVANVAININNQQALISAAWQPSTVYTLTLAGSAPLTFRTQTQAQPLQIEGAAYSLLLPETTAELRLSGRENSRLTANLYAVDRAVLAAALQQPQTPLNPQRYNLQPQQQWQIAAGPERTISITPTQAALLLQVQAPNAELVQHVLIWTPYRAQLLATPEQAQAWIVDLVNRQPVAAANLSILAGANQLATGQSDSQGLWQSSIQGSSGRLVLLGGEPQAPIVAETIIRPQRQAPSLSSQLLLDRQSYLANQQLTIIGSSEFAADGMTTPTLTLAVLDPSGQAIAPEQTLVLSQSLWITKVQLAADVQPGLYEVRLRYANQVIASQNFVVNQPDLAYRVVLPELQATNAIVSAEIISDLPSQHGLWRLLDQRNRQVNAGSWHSNAAGIAQFDYQQSQTLLGDYVLEIQLGEQVSYHPSQIHYPAQLAAKAEQQLLNPNQPATINFQLRDQQGMALSNRALQIEVQGAISSTQSLRTNAAGEVVWRTNGLRAGLWLIRASSPDAASVEVPLWVLGAKSDQLIGRSQSSLVETTELALAPLTNLAATNVLVSWFEGSSIRQQIQPWVAGQSIAITPSLSNTQQLEVALAWLDAEQLISSSSQIPFQAVAPLDLTMVVSGSQLVLATQRAGRPVASMVGLSFQSIQTSASQQRLVRTASNGQAVLDLQGFGEGWRIQALASDGLNSAEATTLYAANPLIDAQMLLPERLIVGDQLSVTARLNLLATRGGIPSVSLSVDSAYLAALAEPTTGNSGRIYTTTQALVAANLGTTTLTATIEVNQQTQIITKALTIQPPSQVRLQQSRLLTEATDITWQVPTANQAASINIVIASLAQASQALPSQLPGDDPLTLAGRIALSRYAAQPAQAEIELLAKQQLTNGSWSWDAQAGDLQLTALIVQLIATEQRSPQLRQLEDQAARWLALVSPLDPDLRSEMLLALAHSGKTVEAQITSLLKNRQLTTAQRLRLIYALVLLDSPQADQYLLEVSQMLAQPLTPSAWMSRTRQAALIGLIFERSQPSSALRAQVLKLIAEGWNGTTWEDLPSSVAVFQLTQQDFPTRGDYRLGLNGAALSDYDQASSLMLPITNQLNVQIEPNGPILLASQASWQNPATQAYLLHSSSEDQLAYGEQWLWQGYLVLEQDLSLLQLRLAAPSGVEWQLGSATGLNWHDGLFSAANVRAGIYPIQLLGVARHKGQFAWPAPQLTSGGQIVELKQTAPPVLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P4</accession>
    <name>A9B5P4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1634"/>
    <dbReference type="EnsemblBacteria" id="ABX04277">
        <property type="protein sequence ID" value="ABX04277"/>
        <property type="gene ID" value="Haur_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1634"/>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012431_0_1_0"/>
    <dbReference type="OMA" id="EWQYACK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1658-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="29472" checksum="5E9741BE96C09AC6" modified="2008-01-15" version="1">MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAAFAMAQVPVTNALYAEWIKHSGQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSEVNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKESMRGGLAPVGSYPQAASPFGVYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRFRLHPERSTHLLGFRLAYSLLESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W6</accession>
    <name>A9B5W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3122"/>
    <dbReference type="EnsemblBacteria" id="ABX05759">
        <property type="protein sequence ID" value="ABX05759"/>
        <property type="gene ID" value="Haur_3122"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3122"/>
    <dbReference type="eggNOG" id="COG2133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024435_3_1_0"/>
    <dbReference type="OMA" id="GINHHWT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3154-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735477" evidence="2">
        <location>
            <begin position="25"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="3">
        <location>
            <begin position="140"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="418" mass="43900" checksum="6DD5046BBA839EFE" modified="2008-01-15" version="1">MRKALLLISLLGLLAACGEQQVDAPIAPTTVPLNQAAGSSTTPVATATTSIVPSPEPTTSAGKPARNAPTAVVEPTDAVTLPDGFGISVFQSKLAGPRMLAIGPDGAIYTAERGEDRIVRLPDRNADGLADGVEVIADGFDSPSSMIFDQAGNLYVAETTKVIKLTQPDAEGKYTQRQTIIDGLPAGGHSTRTLLFSPDESKLYVAVGSSCNVCNEEDERRATVMEYDPDGSNGRIYAKGLRNAVGITWRPGTNELWATNNGRDMLGDDQPPETVNVATSAGLDFGWPRCHSGRIADPEFGKDANACQGVTPPAVEMQAHSAPLGLAFGNGSNFPEPYQSGLFVAFHGSWNRSSPTGYKVVFIPVTDGKAGNAQDFATGWLTDAGAVWGRPVDVIVGRDGSLYISDDAGGAIYRVFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B665</accession>
    <name>A9B665_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3640"/>
    <dbReference type="EnsemblBacteria" id="ABX06276">
        <property type="protein sequence ID" value="ABX06276"/>
        <property type="gene ID" value="Haur_3640"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3640"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_0"/>
    <dbReference type="OMA" id="WYAYAMI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3679-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="76"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="33712" checksum="A5DC915DA8009DE7" modified="2008-01-15" version="1">MGSQLLTPAERRHQWRRRLTPYMFLLPALLIFGIFMLYPIIASLQLSFESQLNPNSGFSLDNYRRLFGDTVFRKALINTVFLLVFQVPLQLGLAMVLAVLLNSAVLKFRTAFRLIYFLPAITALFAVALIFRLLLNDEKGLINYVLNGLGVQPVPWLTNAWPAKFSLVMAITWRWTGYNMVIYLASLQSIPTELYEAAELDGAGAWAKFWAITVPMMRPTILLTTVLSTIGTLQIFDEPYLLTRSGPSNETLSMATLLYRTAFQNAEFNYASAIAYAMVLIIAVFSLLQFRIAQRGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q4</accession>
    <name>A9B6Q4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1720"/>
    <dbReference type="EnsemblBacteria" id="ABX04363">
        <property type="protein sequence ID" value="ABX04363"/>
        <property type="gene ID" value="Haur_1720"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1720"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OMA" id="IDDLHHK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1747-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030287">
        <property type="entry name" value="FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF675">
        <property type="entry name" value="PTHR24220:SF675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="8"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="37169" checksum="FAFD6573775941FE" modified="2008-01-15" version="1">MQTANLAINCRGVSKTFNATTVLDQVDFQLPQGSLGALLGPSGCGKTTLLRLIAGFETLDQGQIWLGQREIANSHRQVPPEQRQIGMVFQEYALFPHLTVGQNIGYGLSRQTHKQQRIDELLELVGLSGLAQRMPHELSGGQQQRVALARALAPKPQLLLLDEPFSNLDAGLRDQVRTATKQILRQVGATALFVTHDQEEALSLADQVTVMLGGKVLQSATPHELYLRPTSRAVAEFVGEANFLPGVARENRVECALGQLLLTKPMHGPVTLMIRPEALNLVPDPSGHGQIMGQRFYGHDQLIDLQIGNLTIAARTGPRLDLAPKMQVGVSVQGPVVAFQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Q9</accession>
    <name>A9B6Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate reductase/succinate dehydrogenase flavoprotein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04368">
        <property type="protein sequence ID" value="ABX04368"/>
        <property type="gene ID" value="Haur_1725"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1725"/>
    <dbReference type="eggNOG" id="COG3573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022946_0_0_0"/>
    <dbReference type="OMA" id="PEDHWPR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1752-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="UCP036654"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="PTHR43260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="6"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="551" mass="59862" checksum="C77EB33324AE79E5" modified="2008-01-15" version="1">MHYDADVVIVGAGLAGLVAAAELADAGKKVILVDQESEQNLGGQAFWSFGGLFLVDSPEQRRLKIKDSYELALQDWLGTAAFDRPEDYWPRKWAEAYLAFAAGEKRQWLYDQGMRFFPVVGWAERGGYGAIGHGNSVPRFHITWGTGPGVVAPFERRVRAAAQKGLITLKFRHRVNQLLLNGGAIAGIEGDILEPSSLPRGAPSSRKVVGSFTFHAQAVIVTSGGIGANHDLVRKNWPERLGQAPKTMVAGVPDYVDGRMLAITEAAGGTIINPDRMWHYTEGLQNWKPIWTNHGIRILPGPSSMWFDALGQRLPVPLFPGFDSLGTLKHLMHTGYDYSWFILTQKIIEKEFALSGSEQNPDLTNKSVRQVLGRVLPGATPPVEAFKRHGADFVVRDNLADLIKGMNALTAEPLLDAAAIEREIQARDREMTNPFTKDMQITALRGARNYIGDKLIRVAKPHKILDRSAGPLIAVRLNILTRKSLGGLQTDLSARVIGQDGQPISGLYAAGEVAGFGGGGMHGYRSLEGTFLGGCIFSGRTAGRAAAEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B726</accession>
    <name>A9B726_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3257"/>
    <dbReference type="EnsemblBacteria" id="ABX05894">
        <property type="protein sequence ID" value="ABX05894"/>
        <property type="gene ID" value="Haur_3257"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3257"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_828391_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3292-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="335" mass="36322" checksum="2B4AFDCBBD4063DD" modified="2008-01-15" version="1">MAADVVQSDYEQLGQVATRFQKLHDQQTQMEAMLRQTYQQLRTDWKGDAAVAFFGEMDDSIFPALKRLQTTLTSASALTTQISQIFRQAEEEAAKGIQFDGGGVAAGGGAGAGASFSAEGGSFDAGGGGGAGLDPAISARWATLTPAEQAAVLQSISNEICDKYGIEHVPVTVSDLADPPGLDLFGYRNDQGVFIDLDNMGDPDRVLNTVAHEVRHEVQRQMANLANPSNFDKFLRSIGIQAEPTWPMNDVTEAMANEWHENFNNYITPESDFAGYESQPLETDARNYGETYRDNLTLTDFERHIPTPKPEPLPVPIPGPSPTPPATTPTPRTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B730</accession>
    <name>A9B730_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3261"/>
    <dbReference type="EnsemblBacteria" id="ABX05898">
        <property type="protein sequence ID" value="ABX05898"/>
        <property type="gene ID" value="Haur_3261"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3261"/>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037618_3_0_0"/>
    <dbReference type="OMA" id="INSEFRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3296-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="22655" checksum="7D87F36874EE2F05" modified="2008-01-15" version="1">MDYTNIRQYIAATRLIVVMPHCGRSFYANGLGGQQIEEFLAAELPQLIDAQYTTIRQREGRAIGGVSMGGYGALRLGLRYPQHWSAVFSHSGAVDAPRWIDDPSNMVIFGPVDSPIRQEYSLFRMLEQLVVPIPAMHFDCGIDDFLVEENRLFHHALRQQHIPHIYRERPGGHTWRYCDENLAASLSWVCQQLDLANQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B752</accession>
    <name>A9B752_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_3699</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3699"/>
    <dbReference type="EnsemblBacteria" id="ABX06335">
        <property type="protein sequence ID" value="ABX06335"/>
        <property type="gene ID" value="Haur_3699"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3699"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_5_0_0"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3741-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="11">
        <location>
            <begin position="332"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="393" mass="43902" checksum="C494E109EF7821E1" modified="2008-01-15" version="1">MLTIDEILSRGVSEVIVEANVRRKLNAGKPLRLKLGIDPTRSDIHIGHAVALRKMRQFQELGHTVVLIVGDWTAQIGDPTGRDESRPRLTVEETKSNAKYYMDQVFKVIDPAKTEVRWQSEWFGQFDLEKAFGLIGRFTVNQMLAHETFRKRYEAGQQLTVLELMYPMLQAYDSIAIKPDIEFGGTDQKFNILAGRQLMEQMGMESQDVILVPLIIGTDGRKMSKSFNNSVDILMSPNDKYGKIMSMGDDVLPVYYEVWSDAPLAEVKAMSEAIKAGSVNPRDLKMQLARDIIRQLDGEAAAAEAEAEFIRVFQQRDLPTDMPEVALSEAANIVDLLVSTKLAASKGEARRLIDGGGVRLAGEKISSYDSLVQPVGEQILQVGRRKFVKLLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D7</accession>
    <name>A9B7D7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3784"/>
    <dbReference type="EnsemblBacteria" id="ABX06420">
        <property type="protein sequence ID" value="ABX06420"/>
        <property type="gene ID" value="Haur_3784"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3784"/>
    <dbReference type="eggNOG" id="COG2142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1903820_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3826-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="15079" checksum="B21014C3E150FB6F" modified="2008-01-15" version="1">MVHRDVISVTSRAQKVKVEPGAGTLLWILQRLSSYGLLLFLPIHLYFTYFTKLDTPALTYNGMRETFSAFPLWYVLNEGLLLICALFHGLNGFRNVIYDWTTNSAVRHTVNFLLIVLGIAGAILGFWTLWALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J0</accession>
    <name>A9B7J0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0311"/>
    <dbReference type="EnsemblBacteria" id="ABX02963">
        <property type="protein sequence ID" value="ABX02963"/>
        <property type="gene ID" value="Haur_0311"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0311"/>
    <dbReference type="HOGENOM" id="CLU_1508618_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-314-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734614" evidence="2">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19637" checksum="02FEC6302EA1B534" modified="2008-01-15" version="1">MRILRFLFVALALLVLLPNRAFADNPNEQVLIDEVRGAYRVVATLAPNPPAVGEALLRVVITDATSGQPSPLNLVQLYAAPDSIGREELFTMLPENQDRNAGRYTSDRLRFTISDQWTMRLVLGAPEGEMVFTTKVQVDSVFKEIGEAAVIAVPATLVGLAVVFIGYKIWRKKRQAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7K4</accession>
    <name>A9B7K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0325"/>
    <dbReference type="EnsemblBacteria" id="ABX02977">
        <property type="protein sequence ID" value="ABX02977"/>
        <property type="gene ID" value="Haur_0325"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0325"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388195_0_0_0"/>
    <dbReference type="OMA" id="ENDIPDF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-328-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="604"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="711" mass="76829" checksum="0CB4215882D5F97A" modified="2008-01-15" version="1">MIFILQSIALAISIFNAIICLWLGMTVALDGGRERGPRLAAAGLLMAGVFFLIHAAIIGRGPPVVDVGLPFWWRVISVVSLLAPYAWYATMIWYTGVSGKSLRIHKLLLFTMGIFIGILGLVLTAIYPLPQEARILALKIVPAWLVANLPFIVAGYLLALIMCFSLPIHALLTGPGRRNNLPHQAWLRVRSWLIRTSLLGLLAGIVALIGAVIVFSQGAVGRTPEVAWLADRAIELFFQLDVMVLIVVAAALGAAGQAMGAYAAFTDRPLPQWNRIDQWRWLVAIAGGFALMVGVSSALQVASIYIVLFATTLASLAYGLLSWRYRVEHEAFMERLRPFVGSLHFQDRLLDGGASLSASVEGLVEAVSRDVLRAERACLLLRDAVPGLPNVISYHWGQTPIPLLEQLPISNERRTSGIRLEAQSGAEWAVPLWDGRGLAGALVLGSPQAGAVYSEELMEVAAACCARLTDALAGERAARMLGDVLRQRIAEVKVLGSQGRRTLHDDVLPQIHAALIHLSAVSANDPMAQQTIQALSEAHTKLSALIRSLPPATPHRLAQGGLAQTLHDMVLVDFGNAFDQVSYTVAPAAEARLADTPQFIGEVISYALQETLRNAARHARGNDPRRTLQMRVQIDWQHGLVVDICDDGVGMQPHQSSSSGSGSGLRLHRGLLMVIGGSLNIATPGQGGTHIHIQVPEELWNLPVLEPEEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z0</accession>
    <name>A9B7Z0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3286"/>
    <dbReference type="EnsemblBacteria" id="ABX05923">
        <property type="protein sequence ID" value="ABX05923"/>
        <property type="gene ID" value="Haur_3286"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3286"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_7_0"/>
    <dbReference type="OMA" id="QQGKYEQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3323-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="41"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="25130" checksum="FA4624D6EDBC37FA" modified="2008-01-15" version="1">MNKSVATKKRQARTRKPQGGLPREVKMLLWLSVPVLLIVAVVMLTKAGAEPAQTVDVSRLIYPDSPVLGKTDAPVTIVEFLDPECESCRAFFPIVKDVLAQNGDNVRLVVRYFPLHNNSVLAIAATEAAGNQGKYWEMQELLFNKQSEWGEKQTPQTALMLQYAQELGLDGDQFAKDLSDPKIMQKIERDNADAQALNVRGTPSFFVNGKEVSSLSQAALQSAIDDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B819</accession>
    <name>A9B819_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3316"/>
    <dbReference type="EnsemblBacteria" id="ABX05952">
        <property type="protein sequence ID" value="ABX05952"/>
        <property type="gene ID" value="Haur_3316"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3316"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105965_0_0_0"/>
    <dbReference type="OMA" id="AMNALYI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3353-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="251" mass="27507" checksum="E678C578E17C4CED" modified="2008-01-15" version="1">MMKTTQPAHPIAWTLGNLLLFCGMYLLLYVGGMYADDFYNRLAARGDSTLPIAAPIIATPEPAITTFQAPTLNQQTASDQPPTLVTSDHSTISRIQIPRIEVDQKVIEVGWELQDDVATWQVAKYAVGHHQGSANPGEPSNIVLAGHVGGSAPVFDRLIETQPGDQIVLYSNGQQYLYVVQSNERVQEVGVSEEQRLTNAAYMNPTSTETITLITCWPPAGPNAFDQRIIVRAVPYTIATEQPAGSNWQMR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B2</accession>
    <name>CLPX_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpX</name>
        <name type="ordered locus">Haur_3829</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B8B2"/>
    <dbReference type="SMR" id="A9B8B2"/>
    <dbReference type="STRING" id="316274.Haur_3829"/>
    <dbReference type="EnsemblBacteria" id="ABX06465">
        <property type="protein sequence ID" value="ABX06465"/>
        <property type="gene ID" value="Haur_3829"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3829"/>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_8_2_0"/>
    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000097959" description="ATP-dependent Clp protease ATP-binding subunit ClpX">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="ClpX-type ZB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="122"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="432" mass="47228" checksum="B574301E73F758D4" modified="2008-01-15" version="1">MAQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPILPPTLPIPHAIRDHLDEYVIGQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLVGPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDVETILLRLIQAADGDVDRAQMGILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPFDTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHFGFIPEFIGRMPVVAALTPLDKDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAIVERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVITAETVRDGAMPTLIRRTSSRSRAGKQPTTKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E0</accession>
    <name>A9B8E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3859"/>
    <dbReference type="EnsemblBacteria" id="ABX06493">
        <property type="protein sequence ID" value="ABX06493"/>
        <property type="gene ID" value="Haur_3859"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3859"/>
    <dbReference type="HOGENOM" id="CLU_1480119_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3901-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="20359" checksum="B31CC4E1E39E39EC" modified="2008-01-15" version="1">MSAKPTNEWRFKILLASLVIIFMFAGLSQASGKTSPLDHGVDNPYPMPTRTRVPFVTRTPRPTHVPITRTPRPTRVPITRTPEATRTPWPTPLATRTPLATRTPEATRTPWPTRTPEATRLPITRTPEATRTPWPTPLATRTPLATRTPEATRLPITRTPEATRTPWPTRTPEATKTPTPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8F7</accession>
    <name>A9B8F7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3876"/>
    <dbReference type="EnsemblBacteria" id="ABX06510">
        <property type="protein sequence ID" value="ABX06510"/>
        <property type="gene ID" value="Haur_3876"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3876"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1608596_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3918-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18373" checksum="4388284BB0F998B1" modified="2008-01-15" version="1">MQQQTEQLSDGQRLNAAQIWAFLAKAAVGRLATHDHAHNQSNLTPLFFVCEAPHIYFATQPGHKLNLLRRYPQGVGLQADAFDPESSTSVFVWGRYRDVPLGAEYAHATRLLAFKYGTGFWQQILDQATKALKAGPRAVITTISQATTGCIQIERIGGRRWEHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J1</accession>
    <name>A9B8J1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07655">
        <property type="protein sequence ID" value="ABX07655"/>
        <property type="gene ID" value="Haur_5025"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5025"/>
    <dbReference type="HOGENOM" id="CLU_1832423_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5088-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025844">
        <property type="entry name" value="Herpeto_peptide"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14409">
        <property type="entry name" value="Herpeto_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="16418" checksum="697F3EE1D09F590A" modified="2008-01-15" version="1">MTTRWFADRMTRYQLLHTHPDWSNRQFAATTQRSRAWVKKWKARLGSPPHPDPQMVCQSQSRARKTPASPWTERVITRILALRDTLSAQYNRVVGAKTILAYLQRDPDLANEQRTASPVTIWKILRQHQRITLSHDMVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q4</accession>
    <name>A9B8Q4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine acetyltransferase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07718">
        <property type="protein sequence ID" value="ABX07718"/>
        <property type="gene ID" value="Haur_5090"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5090"/>
    <dbReference type="HOGENOM" id="CLU_1370569_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5152-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="199" mass="22238" checksum="9E1053695AF2926A" modified="2008-01-15" version="1">MTLTDLATLLWWDIAVNRGLSWDCIRACLLMIEVRCEQYGYHQYCHGRLPRLGWYLIRFFGSIMQWFLCRANIPGTVTIGRGLRLPHPQNIIIAGYAVMGEFCTIYQNVSIVWNGFKPTRPQTPSIGDRVLFGTGCILIGDIVIGSDVLIGAGAVVNCSIDSGHRVTSQPPRITARPPSLQAAKPGSSRHLHDPYSIWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8U9</accession>
    <name>A9B8U9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07763">
        <property type="protein sequence ID" value="ABX07763"/>
        <property type="gene ID" value="Haur_5135"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5135"/>
    <dbReference type="HOGENOM" id="CLU_1882898_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5197-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15495" checksum="6C3858BF11D0BAEC" modified="2008-01-15" version="1">MDNKKYSNFSSISESDFNDSNVNVNSSGNITQNVYRNTGNGSQYIYNGIGNQNISNQNISNQNISNQNISNQNISNQNISNQNISNQNISNQNISNQNISMKYIKRDMDHRKYDDMIRIYIILAFIFAIIVIWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9B2</accession>
    <name>A9B9B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5299"/>
    <dbReference type="EnsemblBacteria" id="ABX07926">
        <property type="protein sequence ID" value="ABX07926"/>
        <property type="gene ID" value="Haur_5299"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5299"/>
    <dbReference type="HOGENOM" id="CLU_1813154_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5361-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="15558" checksum="2FC5097761D8C585" modified="2008-01-15" version="1">MATTSKSIRVGERSMQLLDALRIQLGDQYLSEAALLNEATRRGLLLLAVEAWHAEAGQYGGYSPKELARVLRHELTAVFNFLLEQDELPPMLRIAPAPLPMTVAPMVAAEPVTAPEPTAATVEIDTSVMDLMELAGQDEEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF6</accession>
    <name>A9AUF6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0424"/>
    <dbReference type="EnsemblBacteria" id="ABX03075">
        <property type="protein sequence ID" value="ABX03075"/>
        <property type="gene ID" value="Haur_0424"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0424"/>
    <dbReference type="HOGENOM" id="CLU_1658410_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-430-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="162" mass="18512" checksum="BB17EFE14E132241" modified="2008-01-15" version="1">MQQILIACGSNQLGQIFALVGVLVLFFINLGIKWFFLAKTRRSARRSLFIDSFGLMFMTGVVTVFVFISAYILPTFLFVIEIGFFYSYQIFIWAIVCIVDTFLIERWLLKPKAQAISLNDDQQLQVEAVPMSYQPAWAVALQSNTLIVILVALFFQMIDSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUS2</accession>
    <name>A9AUS2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1956"/>
    <dbReference type="EnsemblBacteria" id="ABX04599">
        <property type="protein sequence ID" value="ABX04599"/>
        <property type="gene ID" value="Haur_1956"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1956"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_312548_0_0_0"/>
    <dbReference type="OMA" id="KEFRRCE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1985-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="488"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="938" mass="105950" checksum="6EED9874EB01EA5D" modified="2008-01-15" version="1">MARVDDRPLFYAAAQSFVDRALRADDSLFTPGVAVWSAANLDDLYQRFVGQPDESADSFMIKFQRQLHEAQPTIIQLAAELQFVYYLISRKITGRAKRDQINTILKWSPEPVSIPHELDGALDQGIANTGTAYQTYKFYQLSFIIEFMQHWKGLSQAARTTALADPWEFKQILFSLPIKTAYAAREMLLHLVHPDSFESIVSRDHKANYARQYAHHKQTTSNDIDRQLWEIRRALTPQYGANFSFYAIQHDETQRPDFPVPLPLGPKLRPYIQLVAMLSTNSYSAEQIVDVLGQANPPLVQLTARPNADDLLDVLQLLRLVEQLPDDRYRRWPHLNDLHEETMLRYSALTLVLPDSEANDDYWLPIMAMPFDGVAHPAEAWPGPALLRDWYREAGLIEQGEHSWLRSRPAALQPIANPTTPTAHAINSFLEHIERVQRSQRSTMDSALQDQPLPQLTTAVLNERIAELQRELLVNRVTLLRIYRALIAGQHVILSGPPGTGKTHLAQRLPEIFWRDTDASISLRMPTSPALPPTEPPIEERHTRHGYAVQIETATETWSSRDIIGGIVPQLQRSAGGKTLVYGVRHGCLTSAVLSNYAGYDGENVPNPETLQRTEVMVKQQRYRGRWLVIDEFTRAHIDAAFGSLLTTLGGQRNAPLSIPTDDGVVVQVPLPRDFRIIGTLNSFDRHFLNQMSEAMKRRFVFIDLLPPSSDDADEEQGIAAYRALLRLSDQKLDTIASNDAAGRATWRGVLNVNREINRDGDGSRVNYRLEVENQDAKDVLDSFWRIFSAIRVYRQLGTAQAEAVYAATFAGHAIGLSWHDALDYALADTLADQLQVLNRDEQRALLAYLAYAHNPKEFSEQLKTIIKSLPLPRQASHLTQLQTASPKHASGSINIANIDELTMTHISQIFDLGTELLLDQTSQFAQRLRTFSSERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUT6</accession>
    <name>A9AUT6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3890"/>
    <dbReference type="EnsemblBacteria" id="ABX06524">
        <property type="protein sequence ID" value="ABX06524"/>
        <property type="gene ID" value="Haur_3890"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3890"/>
    <dbReference type="eggNOG" id="ENOG50331AP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116730_1_1_0"/>
    <dbReference type="OMA" id="REPATHD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3932-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="173" mass="19467" checksum="96A2F3529FDFB76F" modified="2008-01-15" version="1">MSITQHPILAPLIAQSNHIDVKTRQIQTTQPEHELRRFIAAMIGYNPRWMQSLYAIRWGFVRLLGMRQQGIPNSNQLRPEQVPMQVGQNLGFFKVTAAAEGQYLVASASESHLTAWLAIVLEPLGGNNYNLHTVTIVCYHAWTGPVYFNVIRPFHHIVVNQMIKAGLAGQPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV14</accession>
    <name>A9AV14_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3970"/>
    <dbReference type="EnsemblBacteria" id="ABX06602">
        <property type="protein sequence ID" value="ABX06602"/>
        <property type="gene ID" value="Haur_3970"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3970"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_0"/>
    <dbReference type="OMA" id="WDELTIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4012-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="121"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="376" mass="41285" checksum="DB41338FF8EBA391" modified="2008-01-15" version="1">MRIELTEQQASAKAAFRAFVDHEIVPYADQFDREERVPAAVIQKLAREGYLGQVVPEEQGGTGSDMVTFGILNEELGRGCSSIRSLLTVHSMAAFAVLKWGSADHKSRFLSRLVSGEIIGAFALSEPNVGSDAKSVETSARLVGDRYVLNGRKRWMTFGQIADVFLLFAQVEGKVTAFLVERNSPGFSTEPITGILGTRGSMLAELRLDDCEIPKENRLGGLGFGLAAIGTSALDIGRYSVAWGSVGIAQACLEACVEYTSTRRQFGVPIKDHDLVRQMMTNMITNTKAARMLCYQAGYLKDSGDSRTVMETWIAKYFASTAAMKIAADAVQLHGANGCSEEYPVQRYFRDAKIMEIIEASTQLQQMNIAQYAYEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV84</accession>
    <name>A9AV84_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nicotinamide mononucleotide transporter PnuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0513"/>
    <dbReference type="EnsemblBacteria" id="ABX03162">
        <property type="protein sequence ID" value="ABX03162"/>
        <property type="gene ID" value="Haur_0513"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0513"/>
    <dbReference type="eggNOG" id="COG3201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076589_2_0_0"/>
    <dbReference type="OMA" id="WPDAYIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-521-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034257">
        <property type="term" value="F:nicotinamide riboside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006419">
        <property type="entry name" value="NMN_transpt_PnuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36122">
        <property type="entry name" value="PTHR36122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04973">
        <property type="entry name" value="NMN_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01528">
        <property type="entry name" value="NMN_trans_PnuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="24305" checksum="0E09471BF1AD9024" modified="2008-01-15" version="1">MDLASFFDINTIAFTLFGYPMSYLELAGTIFNLWSVWLVGRGRISNWPIGLIGVVLFFVLFYQIQLYADTFEQVYYFFTGIYGWWHWSKPKEQAAKPRYSSRNYNLLALGITVVGTLILAFIIGNLDQWLPAYFPAPATYVLIDSLTTVMSFTATILMAQRRIECWYYWITVDVIAIWLYSVKGTLLVALLYAIFLVLASNGWRLWRKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC1</accession>
    <name>A9AVC1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="7">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1969"/>
    <dbReference type="EnsemblBacteria" id="ABX04612">
        <property type="protein sequence ID" value="ABX04612"/>
        <property type="gene ID" value="Haur_1969"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1969"/>
    <dbReference type="eggNOG" id="COG0415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_2_2_0"/>
    <dbReference type="OMA" id="WQWSASS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1998-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="486" mass="55386" checksum="85E3F0A1930C69D3" modified="2008-01-15" version="1">MPVICWFRRDLRLTDHRALYAAAEASAGAVIPVFILDDTILHDGYVGAALIAVTLAMLEALDHDLQQRGSRLIVRHGQPLAELQRLVSETQASGVYWNRDYLPYAIKRDSAVKHWLREQGLQAHSFHDSVLVEPEGLKTKTEQKPYVVYGSYVKRWSELAYHQAEQLVPAPSKFVAPPSDLASLPIPSLADLGFELQQTIPQVGETIAQQRLAQFFDRRQKLSVLKYTKAREVPAEAGTSQLSVDLRMGTISIRQCLKQAVDLLTEPLNAEQRQGVDTWLKELAWRDYYTQLIYHNPYMLNGSLDPRYDQIIWRNDPSEFLAWQQGQTGYPIVDAGQRQLNQMAWMHNRVRMISASFLIKDLLIDWRWGERYFMQQLCDGDPTANNGGWQWAAGSSGPSAQPYFRIFNPIAQSKKHDPDGQYIRRFVPELANVPDHYIHEPWTMPPAVQAHVGCVIGRDYPAPLVEHSFARERALAAYRTALQTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN2</accession>
    <name>A9AVN2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4000"/>
    <dbReference type="EnsemblBacteria" id="ABX06632">
        <property type="protein sequence ID" value="ABX06632"/>
        <property type="gene ID" value="Haur_4000"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4000"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_0"/>
    <dbReference type="OMA" id="TIDICRV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29913" checksum="3A07F900D3A7CAEB" modified="2008-01-15" version="1">MTEKQTDTANYSLTVRNMNVYYGTFRAINNVSLNIERNKITALIGPSGCGKSTVLRSLNRMNDLVNGARVEGEVLFHEQNLYANDVDAVEVRRRIGMVFQKPNPFPKSIYDNIAFGPRINGWKGTKSEMDDLVERCLRQSALWDDVKDKLKESGLALSGGQQQRLCIARALAVEPEVILMDEPCSALDPISTLKIEELMMELRQRYTIAIVTHNMQQAARASDYTAFFLMNDQRAGELVEYGPTGDLFTNPKDKRTEDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN4</accession>
    <name>A9AVN4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4002"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06634">
        <property type="protein sequence ID" value="ABX06634"/>
        <property type="gene ID" value="Haur_4002"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4002"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050643_0_0_0"/>
    <dbReference type="OMA" id="ICVMEVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4044-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="5"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="31179" checksum="61155C1E305B7CA1" modified="2008-01-15" version="1">MDFTAALPANPLEKPGYRLDFQDEFATEQLDQAKWLPYYLPQWSSRERSTPRYHLANQRLILEIQADQAPWCPEFDAQTRCSSLQTGVFSGALGSPDGQHRFNQACVVRELQDSIRTYTPQYGYFEMRAKATIGPNNVVALWMIGFEDQPEYSGELAIMEIKGWNIGATGLKLGYGVHPWGDSQLTDEFFEDEVAIKVSDYHIYAAEWTPSQIDIYLDNRKLRTIQQSPNYPMQFMLGMYDLPLRQPTTAQYPQQFEIDYVRGYQPLHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS0</accession>
    <name>A9AVS0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gmad1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4038"/>
    <dbReference type="EnsemblBacteria" id="ABX06670">
        <property type="protein sequence ID" value="ABX06670"/>
        <property type="gene ID" value="Haur_4038"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4038"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_440661_0_0_0"/>
    <dbReference type="OMA" id="TELDIGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4081-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018910">
        <property type="entry name" value="Lipoprotein_LpqB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10647">
        <property type="entry name" value="Gmad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732179" description="Gmad1 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Gmad1" evidence="3">
        <location>
            <begin position="281"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="596" mass="62276" checksum="6E27CBE5B1AFCC3C" modified="2008-01-15" version="1">MKLLLRQRVSLALVVVALAACQQAPQPTARPLQNELTILALTPTGTATPTATVTLTPAPASPTTEPSATPTRTVGPSPTKGASPTAGPSPVGTPRATPASTPTANQSSSFCTQPFGAVTDERFSARLNNAGLDRTPNGDRLFLELTSSSGPVNGVVRCVPPAAAQLLAGDSAIASVIQIDLPLWRHDDLWRSSSVTLTKVLKLDTLQHVRSVVSQSSSDSAGVLIEIGLDQALPFTVQLDGGRLNVVIADSATATLGDDPLAKSNGSPSAPKQPVVFASKGDLYRYESSRVVPITTTLAIESAVAISPDRTQIAFCRANPDGLPTQGALWTSTIDGDNETLVADVGGCAEPAWSLDGGIIWFTAPWSDAAPDSYRLWQVKANGGDASAVSPLDEWSRRMPHALPDGSVLTVGHTDGGQGGLLISNPLSGTDGLLGQASLGNYRSVGQAQVSADGTRIAVEALRADGGADLLVLDQTGKQLDAITDQWWVRPLSWSSDNKLYYLNVACRSGQVLNYSLHSRQGSNDSQIIKGATLGDLGSVAVVDDALLYVRALQSPDNERGAEPMISGPSELWLYDLSNTARTRLIAADDGITSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVZ3</accession>
    <name>A9AVZ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0583"/>
    <dbReference type="EnsemblBacteria" id="ABX03231">
        <property type="protein sequence ID" value="ABX03231"/>
        <property type="gene ID" value="Haur_0583"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0583"/>
    <dbReference type="HOGENOM" id="CLU_1382465_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-592-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="197" mass="22353" checksum="B2B36BA50C814E82" modified="2008-01-15" version="1">MKDISDKYIRKRIDDYSINNSYSIVSRIVMRQYLQKNFLIGIVLFLFILIVSISMNGLFLVKMIAASIISIGLLSFFTFFETILYTDKKAYILFLIIKHFQQTNIQPYQLTTLKDITALEASIVGTKTASTLIIITILITLGPVIVQKVHPLATAIATIVLLLILFTQILQGYADALIRQAIAMYEEQQALLKKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW13</accession>
    <name>A9AW13_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FolC bifunctional protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0603"/>
    <dbReference type="EnsemblBacteria" id="ABX03251">
        <property type="protein sequence ID" value="ABX03251"/>
        <property type="gene ID" value="Haur_0603"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0603"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_2_0"/>
    <dbReference type="OMA" id="YFEMGTL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-612-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="53"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="296"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="435" mass="47123" checksum="415C2D29B486C190" modified="2008-01-15" version="1">MLQTYQDAMDWIYSFLDSEKKLPKNPTEFNLPRVKAMLELLGNPQLRYPAVIVAGTKGKGSTCAFLESIIRQSGLKVGFFSSPHLHSYRERMQINRELISQSQLVDLINQVRPLLEPLDPEVGSPTTYEIGVVLGLYYFATQAIELAVLEIGLGGRYDAINTVNPVLSVIASISYDHTAILGDTLAKIAYEKAGIIKQHVPVISTVQQAEAAEVIAQVAAEQAAPLFIAGMAGLQEQASGVVAEYPLVIVPEQLGLKGEFQMQNAQLATSAALLLRELGFPISDDAIRQGLATTQWPARFEQIANEPLTLVDGAHNGDSARVLLQALKQNYSNRPLTLVLGTSSDKDIQAIIQQLSNSATHLITTCSRHPRALAPEKLAELIQQHVNRPVHQTNSVAEALTLAQQLTSAAGLICVTGSLFVAAEARETHGLAQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW51</accession>
    <name>A9AW51_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0641"/>
    <dbReference type="EnsemblBacteria" id="ABX03289">
        <property type="protein sequence ID" value="ABX03289"/>
        <property type="gene ID" value="Haur_0641"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0641"/>
    <dbReference type="HOGENOM" id="CLU_1882897_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-652-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18319" checksum="8B6C38E4E053F40F" modified="2008-01-15" version="1">MAHTKAVTYNFKNRDFDASVNGEYIGSFPTDLDARMACNRLVLELIELDNRAVEDAEEAMAIGVVEPVAEASAEVPLFEVVDLIPMPAVTATTYANTPIDALARTMVILSRNWQRAIRAGRYADAERIEAHEQAVRSQFRSLSSPSLPPVPVVQQRPTTSRRINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW55</accession>
    <name>A9AW55_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2064"/>
    <dbReference type="EnsemblBacteria" id="ABX04705">
        <property type="protein sequence ID" value="ABX04705"/>
        <property type="gene ID" value="Haur_2064"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2064"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_1_0"/>
    <dbReference type="OMA" id="FHEAFDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2092-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734369" evidence="4">
        <location>
            <begin position="25"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="35032" checksum="95147572C3D2B171" modified="2008-01-15" version="1">MTWLKRGFLVIISLLCMACGQSTATIVPPPMDTNTSNKPVIIATTTQIEDILSVIGGDRISVVGLVPRNGDPHEFEPTPADVQRVATAQAVFMNGAGFEGWIDELIRNAGGQRPVVDLSVGIPLGTIASGFAESGETDPHIWMNPQHMLIMVDTMVTNLIQLDPAGATTFNANATAYKQELIALDAYAEKELAAIPANRRKLVTAHDAMGYFAARYNFDIVGAVIPSATTEAAETSAQDLATLIDAIKAAGVPVIFAEVSNNPKFIEQVAREAHVRVDTLYVDSLGEKGSDAGTYLDFFRTDVQKIVQALKFVLTCKKLFKPLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW76</accession>
    <name>A9AW76_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2086</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2086"/>
    <dbReference type="EnsemblBacteria" id="ABX04726">
        <property type="protein sequence ID" value="ABX04726"/>
        <property type="gene ID" value="Haur_2086"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2086"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="TKTQHRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2114-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="27"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="347"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="380"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="592" mass="64898" checksum="371FB79B9FDBD5C2" modified="2008-01-15" version="1">MKAWQLMLRLIRYRPAIYGFGVLIWSIFFISPLLPGLINRAIFDQLSGAAPAVFGIWTLLALLITTEISRRLLTQLGTAMDISVQYNIAGLLRKNMLKRILAQPGAQALYTSSSAAINNFRDDVEEILTFSIWLLDVFGNVLFSLIALGILLQINQQVTLVILVPLLIVVSAFTVANQRIQRYRQASRAATSKVSDFLGEMFGATQAIKVANAETAVIGHFQQLNDQRRQFMVKDRAFTALLSSVYANTISLGTGMILLLAGEAMRTGNFSVGDFSLFVYYFSMVTRLPSLIGLLLTHYKQAGVSFQRMQQLLKDAAPSALVEHGSITPDQQLDFSPAKALPALQRLDISNLSYCYPNSQAGIKAIDFRLERGQFVVVTGKVGSGKTTVLRALLGLVPAHGTILWNNQPIEQPAEQLIPPNCAYTAQVPRLLSSSLHDNLSLGLNLSANELQQAIETSVLAPDLQHMPAGLATELGSRGVRLSGGQLQRAALARMLVRSSELMIVDDCSSALDVTTEQQLWQGLRQHPTTWLVVSHRCAVLQLADWVIVMDAGQIAAQGPLNDLLETSPAMRELWQAEPSNQKLLLGVDAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE7</accession>
    <name>A9AWE7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ordered locus">Haur_4074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4074"/>
    <dbReference type="EnsemblBacteria" id="ABX06706">
        <property type="protein sequence ID" value="ABX06706"/>
        <property type="gene ID" value="Haur_4074"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4074"/>
    <dbReference type="eggNOG" id="COG1077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052037_0_0_0"/>
    <dbReference type="OMA" id="MDIFQPS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4117-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="200"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="333" mass="35486" checksum="7C4FAE190D061181" modified="2008-01-15" version="1">MARKIGIDLGTANVLVYIKGKGIVLSEPSVVALSRKTNKIRAVGTDALAMLGREPESVEVIRPMLNGVIADYETTKAMLEHFIDKTRGFGKPDVMICIPAGVTTVEMRAVRDAARKAGARRAYLIREPLAAAIGANIPVAQPSGNLIIDIGGGTTEVAVISLNDIVVSNSVRVGGNKFDEAIAAYIKRKYNMMIGERTAESIKIEIGSALPLDRPLTMQVRGRDQVAGLPRTIEVDSNEITDAIQEPLEAIISAVRSVLVETPPELSSDIIDKGMVMTGGGSMLRRINELLTEVTGVPCYVADQPANCVAIGTGLALENLEILRESLSGSDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWF3</accession>
    <name>A9AWF3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4080"/>
    <dbReference type="EnsemblBacteria" id="ABX06712">
        <property type="protein sequence ID" value="ABX06712"/>
        <property type="gene ID" value="Haur_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4080"/>
    <dbReference type="eggNOG" id="ENOG5033AAZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820784_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4124-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="338" mass="37167" checksum="66FDE119EF7001C7" modified="2008-01-15" version="1">MTDDPLTSNQAELAEAEPRRSSSAPPQLRAAISRALSRRKAELQSQSVAEETVAVEIAPTIVAEPEPPMPLRQERYRVAASRALSRLRPSSETPQIANSTSNRGRDRTRTRLRPPTLPNQPLPKLPTDQPVRRELPAAVVAALQPDSLPAPEIQRPPLWVAFVAGLGWTAMLLWVFFGGLSPQSGFGVRSLFGLATVALGLTTWLPMQWALRLPALTWRGTVGWAIIFWILAFVPAPTTTIAAGLPDLPIYLIFLSGVFLASNAMVLPIVYVWGIRRYHNRAQRFDVRRSHRQAAEAGIFCSLCVLLAAMNIFEPVTVLLLIAILVLSEMVILSLQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWK0</accession>
    <name>A9AWK0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_MA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4127"/>
    <dbReference type="EnsemblBacteria" id="ABX06759">
        <property type="protein sequence ID" value="ABX06759"/>
        <property type="gene ID" value="Haur_4127"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4127"/>
    <dbReference type="eggNOG" id="ENOG5033Q65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_579870_0_0_0"/>
    <dbReference type="OMA" id="FHEGIAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4173-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039568">
        <property type="entry name" value="Peptidase_MA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13485">
        <property type="entry name" value="Peptidase_MA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735273" description="Peptidase_MA_2 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_MA_2" evidence="3">
        <location>
            <begin position="62"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="456" mass="50663" checksum="1E4E1D18D6C06745" modified="2008-01-15" version="1">MRRLLCLLIILLLWPHPVAAQTNLPQWLERKTTYISILYPQGSEAEAERYAGYSDAIYEEVTAVVGYRPAPPLTLRIYPTKELYQQVNPAARWLEGIVAHAHTGRREISIAVQQTVGMSDEELRNNVRHELMHIIAAELSDGRLSTMWQEGIAQYVEVPTSQSGYKIALLKQALENNALATWRLLDSAGAVYDNPELGYPQSWSMVSFLIQRYGMARFLAFLEALRTASGYRSALSQAYSLSAESLESEWLAQLPTWIDGGWKQAPSVAFDQASIETALAAGRYSEALTAAETALTIKDDPAIAALREQARKGVRAEDAAAAARVALLEGRYAEAKTAIEQALPLFADLARIDRQKLLNDYLQRADQGLKAQQLLETARRDLNGIRIVAARNNIEQAANLFSQLGDNNGRSQAAQLLESLNLRLKIVGIGLIVVVGLGLAWNIDRRRAMRKRMLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN0</accession>
    <name>A9AWN0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4157"/>
    <dbReference type="EnsemblBacteria" id="ABX06789">
        <property type="protein sequence ID" value="ABX06789"/>
        <property type="gene ID" value="Haur_4157"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4157"/>
    <dbReference type="HOGENOM" id="CLU_083853_2_1_0"/>
    <dbReference type="OMA" id="DERAEGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4203-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="15993" checksum="10F6C54B7604B1C3" modified="2008-01-15" version="1">MARYRVMGILTDRAALDGLLQQLHQSDVKPDDIGVLYASDATVEAKQDRTEVAAGAAAGVTAGSVVGVVAGLMSFAIPGIGPALGAGILGSTVAGAAAGGVLGAFSQIGLGNDLAASYEQALKAGETILAIDNDNADQAGVVESLLRERNIELVNTFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWQ2</accession>
    <name>A9AWQ2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0655"/>
    <dbReference type="EnsemblBacteria" id="ABX03303">
        <property type="protein sequence ID" value="ABX03303"/>
        <property type="gene ID" value="Haur_0655"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0655"/>
    <dbReference type="eggNOG" id="COG3567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_598220_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-666-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021145">
        <property type="entry name" value="Portal_protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05133">
        <property type="entry name" value="Phage_prot_Gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="457" mass="51406" checksum="35F8A18ACD881711" modified="2008-01-15" version="1">MGMFPPTATSSIISQHLHGQRVADDFQRLQQFRAAWEAYRKQDTPPLPIEAGRPNDNVRVNLIKLIVQTSVSFLFGDQVAFSVPDAPPDDPRIQYLDRIWNAAKKMTWLYKQGINGGLCGHIFARIYPEQPLPRIVILDPATVTVRWAADDLDRVECYLIDYSAYEWQGNREVLVSIRQRIERTDTGWRILDQRSQPDKQAFDTLHEAPWPYPFPPIVDSQNLAAPNEYWGEADITPDLIALVNAGDFTLSNQQRIVRFYAQPLTVAKGMDPAQLKHGRDRTVFIPPNADLSIVEMQSELAASLDHHSRIKSSIHEVAQTPEIATGKVEDLGNLSGLALQILYGPLLQKTVQKRMLYGDFLSELNRRLLMIGGFPETTTTVVWDSMLPTDPQAERVVAQADRTLGVSEATLLTQLGYDPAHEREQRQAETPPDHDPMTSKGDADDSNPDAAAPTERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU9</accession>
    <name>A9AWU9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0702"/>
    <dbReference type="MEROPS" id="S09.B04"/>
    <dbReference type="EnsemblBacteria" id="ABX03350">
        <property type="protein sequence ID" value="ABX03350"/>
        <property type="gene ID" value="Haur_0702"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0702"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_6_2_0"/>
    <dbReference type="OMA" id="EDCGYTN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-714-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734390" description="Hydrolase_4 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="75"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="32308" checksum="1C5BD695AABC11F0" modified="2008-01-15" version="1">MKRKLWLGAGLSAAASALAGIAAYAAHRLSGPTAALKRETLFAFTPFETGVDWEEVRFNSVDGLQIRAWWLGRPESKRVVIGCHGHRGRKDELLGIGSGLWRAGMNVLIFDFRGRGESDDSICSLAYHEVGDLHGAIKYVEARLPEAQIGVIGYSMGAAVSLLGSADQPAVKAVVADSSFAEMANLVDFALANRRLPPRPLRALADQITAQRYGYRFEAVRPIEALIRYGQRPLLVIHCTGDTVIPVVDAYDLYAAAQGPKELWIVEDMPHCGAYFADRPAYVKRVAEFFERYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY1</accession>
    <name>A9AWY1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0734"/>
    <dbReference type="EnsemblBacteria" id="ABX03382">
        <property type="protein sequence ID" value="ABX03382"/>
        <property type="gene ID" value="Haur_0734"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0734"/>
    <dbReference type="HOGENOM" id="CLU_1508621_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-746-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19910" checksum="25701354992A8F29" modified="2008-01-15" version="1">MHRPNDSYFAELEQELAALSLAEREAILRELRSHYDDAAADPTADDQILRLGLPFQADQFGRKLKRIHRSAKREAAKHRTMMIIATVIASIAIVLSFVFPWFDGNLLAFILGGTAAICSILSVVGIWLPKQTIGQWLFWSGSTGLTLIGLPSVISFSSFYLIFGPLLLWTGTRLQRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX64</accession>
    <name>A9AX64_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CRISPR-associated protein Cas6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2232"/>
    <dbReference type="EnsemblBacteria" id="ABX04872">
        <property type="protein sequence ID" value="ABX04872"/>
        <property type="gene ID" value="Haur_2232"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2232"/>
    <dbReference type="eggNOG" id="COG5551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063836_1_0_0"/>
    <dbReference type="OMA" id="FELKTHA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2260-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019267">
        <property type="entry name" value="CRISPR-assoc_Cas6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010156">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045747">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10040">
        <property type="entry name" value="CRISPR_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01877">
        <property type="entry name" value="cas_cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRISPR_Cas6" evidence="5">
        <location>
            <begin position="146"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="274" mass="30931" checksum="08B6A7ED9E7F3666" modified="2008-01-15" version="1">MLAQPELIACVLELTATHGTQLERTQGHRAHALFLHLMQESDPVLAEQLHAASQTKPWTVTPLPQQARRLHNGETYPLRIAFLQASLYWPFAQTFLQRPNRQLRLGSSNFNLQAIHTTKQHSPWAGVSSWQSLIDQAQPTDEISLWFATPTCFKLGRDRQGKQRVGLIPDGQSVFQSLLRRWNAFAPTPLASPEQIEQLDIQIKRYQLRTEMLHAQDKQLGFMGKVSYKLDGDAHERRILATLADAALYLGIGAKTTQGMGLVQRISTQQPEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH3</accession>
    <name>A9AXH3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WYL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX06893">
        <property type="protein sequence ID" value="ABX06893"/>
        <property type="gene ID" value="Haur_4261"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4261"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_813018_0_0_0"/>
    <dbReference type="OMA" id="RYLENCR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4308-MON"/>
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    <dbReference type="Pfam" id="PF13280">
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            <end position="330"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="39246" checksum="649165A910B0B023" modified="2008-01-15" version="1">MNTKRQARGIKRSSVMKVQRQMLLLRCLGSGPKTSDALIDEVNSQMLEAYPKAAREALRHDLRALREVFGCVIEYTASVGYRLVSVGDLALLNLTNDEIAALRFLDATYTANSTLPDHQQVRRLVERIIDFLPIERRGALNVGEPILQQAGPVAPYEHDPQIMRSLRKALAQRREIRFRYTSSQRDGEETHRVGPVNIFTRDGHMYLLGYCFDGPQQMVERVGRYVDYRIDYISKNSLTILPRVLPPALPKRPTWTVKYELRDVVARNKKVAHWFADTDIQYRDDGSALVTATVHNLWQTRQILLRYLENCRVLEPPELIDMMRATAQGLRDLYPPSTNEIG</sequence>
</entry>
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    <organism evidence="2 3">
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            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX04975"/>
        <property type="gene ID" value="Haur_2335"/>
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    <dbReference type="KEGG" id="hau:Haur_2335"/>
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    <dbReference type="OMA" id="DAVCFTT"/>
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        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
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        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
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        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
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        <property type="entry name" value="PTHR40082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="1">
        <location>
            <begin position="18"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="29294" checksum="9C97566875A38776" modified="2008-01-15" version="1">MSSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQIDLLILLTGVGTQQLIDAAASVGLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAASPYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRERGAVLHEHSVYEWQLPADISPLLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQALINLGIQQVIMPEQPFMGQMVQRILDHVSVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY67</accession>
    <name>A9AY67_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4317"/>
    <dbReference type="EnsemblBacteria" id="ABX06949">
        <property type="protein sequence ID" value="ABX06949"/>
        <property type="gene ID" value="Haur_4317"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4317"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_002755_1_2_0"/>
    <dbReference type="OMA" id="FIIPCFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4369-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="745"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1216"/>
            <end position="1242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1263" mass="131649" checksum="916045F2A0A2CF8D" modified="2008-01-15" version="1">MLWFTRQSLKRSPITIMISVVLIIAGLVASAGLKRELFPDISFPIVSITTIYPGASSETMDSEVTSVIEKAVNGLSGVQAVQSTSSESFAFTILTFDVDVDPKDAKVEVQEKISSLALPENAQKPTIGTFDFNSLPIVVASVSGENLSNVQARVDGELIPALSAIPGVNNVAVTGGQQEKVLITLDPEKMAANNLTQAQVVQFLQANNLVFPVGTITDEGRSLPLRITHKYSSTNEIENVVVGIKGVDLTGGAGGGLGGATGGFGGAAAQPTAAATPSPTQAPTQPVTTSLIPAALQGFGITSPDQITPAVIAQFPDAGLSQITLPLALALSDESQAALAQRYPEAEVPAELVAFGISAPDQITPAVISQFPAAGLAQFPINLALALPEASQTALSEALAAAPAAPPTPSNGASALPPEFANFGITSPEQITPELIDQIPAQFLSAFTPELIALLSDESQAAIAQKLNNPDAAGSTGVPEALLIRLKDVGTVEVGAVGGSTVTRTNGQASLGLEISKDTTGNTVEIVEAVEAEFAKFNNGDLKIQIVSEQATPINQAVSAVLTEGAIGAVVAIVVIFLFLRSLRTTLVTAVSIPLSIMVALILMRLQGFSLNVMTLGGLTVAVGRVVDDSIVVLENIYRYLNKGANRREAVIEGTKEVAGAITSSTLTTVCVFLPLGLVGGIVSKFFLPFALTVTYALLASLIVAITIVPLLAFLFIRQTKEEPENTWMQRAYTPALLWALRNRAWTLVIAFALLLGSFGFVNFLKFTFLPDSSEKLISIQVFTPAGTDLDSTVAKADEIEKLLLPQRDAGKVRDIQTVIGSAGGANRNRDQSGGASAPNSARFSLTINNDNVTDPTAFAKELEAQIKGVAGLDSVAAEVISQGGGPGNAGLDITLVSSDINKLREANDKIMAAIGGNNASDRFDIANVKSGLAEVKPELEVAVDPKKAIGSGTSTAQIALQIRALLTGENAGTVQLDGTDKPLDIYVQVDPAALDAEKLKALEVGTINPVPLSEVATISEVPGASSIVRINGDRATSISGQFTSDDTFSTQAAVEAEIRDNIGLPEGVIIQAGAQAQSQTDTFNDMFLALGVAVILVYLVMVLSFGSLMNPLIILFSLPLAIIGVLTSLFITGKPLGITTMIGVLLLIGIVVTNAIVLIELVEQYREDGKPVYESLVQAARVRLRPILMTAIATMVALLPLALGLKEGGFIGADLGIAVIGGLFTSTFLTLLVVPVVYSLIESVKTRFGFADKHGKPEADVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB2</accession>
    <name>A9AYB2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0846"/>
    <dbReference type="EnsemblBacteria" id="ABX03494">
        <property type="protein sequence ID" value="ABX03494"/>
        <property type="gene ID" value="Haur_0846"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0846"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_2_0_0"/>
    <dbReference type="OMA" id="DRFDFMW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-860-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="176" mass="19796" checksum="25BB6EBDF4AF9BE2" modified="2008-01-15" version="1">MQTVKMVISGAVNAGKTQFIRAISEIEVVSTERKASDDTKLLKGETTVAMDFGRITISDDLVLHLFGTPGQKRFDFMWEILSEGMLGLIVLVDSTRPETFRETNRIIDFFTSQRDAPYVVAANKQDHENAWAPDELRLALRLPAHVKIVPCVATQKDSVKNVLLELLYVIMQRSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD6</accession>
    <name>A9AYD6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ASPIC/UnbV domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0870"/>
    <dbReference type="EnsemblBacteria" id="ABX03518">
        <property type="protein sequence ID" value="ABX03518"/>
        <property type="gene ID" value="Haur_0870"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0870"/>
    <dbReference type="eggNOG" id="COG4658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432058_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-884-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UnbV_ASPIC" evidence="2">
        <location>
            <begin position="566"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="645" mass="70505" checksum="A33A3BFBF909350B" modified="2008-01-15" version="1">MIRSLWQKYHGRLIVSLILLICFGLAREPQLSAAERSELAKSFQFTPAILPTLSGYPQSTIRTVNPSLAHISAWISSVGAAIAINDLDADGLSNDICYVDPRIDQVIVTPVSQANLRYLPFALNPSPRPYNPTTMAPMGCLPGDFNEDGVLDLLVYYWGRTPLLFFQQPTDGSLTAERFVVEELMSQSERWYTSAGLLADFDGDGHQDLILGNYFPDGAQILDENSSKAESMQASMSRAFNGGNKHFLRWTARPDQPFGVQFMPVEQVLERELNHGWTFALGAADLNGDLLPELYIANDFGPDRLLLNQSTPGKLKFSLLEGQAGFNIPSSKRVGHDSFKGMGVEFSDLNGDAIPDILVSNITTNYGLHESNFAFLSTGDQTGFTQGLAPYRDHSEALGLARSGWGWDIRVADFNNDTSLEIVQATGFVKGTVNNWPELQELATGNDALLADPASWPSFQAGDDIAGHQINPFFVRDATGRYHNLAAELNLDTPHVTRGIATADVDGDGRLDFALANQWESSWFYHNTSPINTKALGLRLRLPLDVNQPLAVLSGYQSDPTPSLAAIGASATITLPDGRTLVAQVDGGNGHSGKRSYDLHFGLGELKGDSQINVEITWRTRDGEIVKTRQLLKPGNYTILLGSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD8</accession>
    <name>A9AYD8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0872"/>
    <dbReference type="EnsemblBacteria" id="ABX03520">
        <property type="protein sequence ID" value="ABX03520"/>
        <property type="gene ID" value="Haur_0872"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0872"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082704_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-886-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="48"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="32591" checksum="1519914D7C2FF170" modified="2008-01-15" version="1">MSLESGLINEVKGKLADQRGTLSSIRQPSRPDQWHDHDQTTHYSAAVERVIGVMRGQSHELLRLEQLADIANLSPFHFNRIFRQTVGLPPGKFLSTLRLDRAKRLLLTTDLSITTICFEAGYSSLGTFTTQFTQVVGVSPRRLRLLRATFETPRLDRLHHQYVHETKPDQQALTVHGSIIAPESFSGSIFIGLYPIAAPLGQPVSCVFLNALGDFQLKAEKPGRYHLFAGAIPWSNDPLAYLLPCEQTAWFARTASVIMLRSDTFTSCGVMSLRRRRPTDPPLLTIPSALTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYG8</accession>
    <name>A9AYG8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MLTR_LBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0902"/>
    <dbReference type="EnsemblBacteria" id="ABX03550">
        <property type="protein sequence ID" value="ABX03550"/>
        <property type="gene ID" value="Haur_0902"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0902"/>
    <dbReference type="HOGENOM" id="CLU_082999_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-916-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MLTR_LBD" evidence="1">
        <location>
            <begin position="120"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="290" mass="33915" checksum="399A573A57E2FC08" modified="2008-01-15" version="1">MTEQAPQLNANDAFIEAAERIRILHKRDLEDAIRDRKRPKLSASPFSQQAIWLEFPTYKRLLEKRAKITVPEVIVRGVATLLECNISERNILLSAAGYKPDPEILSGAALEQHLERYRSIVHNLTIPGFILNHVWDILEVNSLMNRLFEHYMSGFASIPVDDRNILNLMFDPRYGFKRLFSVDIIQWELMARSYIYNFRQATKGFELETWYRAKINYLSQFADFNLIWKQVEANLYKEYDTSLTYFTSQFFGFRSIYITESEKFPYPRINAYISEDLTASIALLATPNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN0</accession>
    <name>A9AYN0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2368"/>
    <dbReference type="EnsemblBacteria" id="ABX05008">
        <property type="protein sequence ID" value="ABX05008"/>
        <property type="gene ID" value="Haur_2368"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2368"/>
    <dbReference type="eggNOG" id="COG3544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074343_2_0_0"/>
    <dbReference type="OMA" id="IPHHQDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2396-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735333" description="DUF305 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="3">
        <location>
            <begin position="50"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20420" checksum="39EAF7A4B44884F3" modified="2008-01-15" version="1">MRRFMMFLGLIVVLSGCGATSQTNSSTNDHGGDHATEAPTTDHGSMSMSDLQFLDGMIEHHRGAIAMAKDAQSQASDPQVQELAKQIIAAQEPEIVQLQAWRKAWFGDAPASDLSALHMGSMDVPAGSESYDRRFLTAMISHHDGAIAMAQSIKASTQRAELKTFAEAVITAQTAENQQMDTWLQEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ23</accession>
    <name>A9AZ23_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4431"/>
    <dbReference type="EnsemblBacteria" id="ABX07063">
        <property type="protein sequence ID" value="ABX07063"/>
        <property type="gene ID" value="Haur_4431"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4431"/>
    <dbReference type="eggNOG" id="COG3211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018570_1_0_0"/>
    <dbReference type="OMA" id="WDIFVFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4486-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="DUF839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="63722" checksum="959AE68F5EAE0273" modified="2008-01-15" version="1">MTSHDQRAERKSIWHDLLERRINRRTLVASGAAAAAVAALPLDLQTAEAAHYHAPLSAPALAQRQAQGSLPFKPISPSTADDLILPEGFRYDLLAHRGHDMGDGSLFGENADFLAFFPIDMLQKGLDQNRPQFGFTRSDLSSTDGLLLVNHEYINPMFISGYTGSGAKSGDQINAEKHMVGMSVIRVKRNSDGRWYFDQTDTAHNRRIDATTPITLTGPAAQLDGGPMAIGSLGNCSGGVTPWGTALSCEENFQDYPNPAPTGYGWEPEIYGKRHYGWVVEVDPFDKNSMPRKHTAMGRFRHENVAVRVGSDGTVVAYMGDDKADSCVYKFVADRKLTNLADRPGNMQILESGQLYAADFANGKWILLDYNSQSALQSAKDSKGNLLFSSQADVLADTQAAAMALKATPVDRPEDIEIHPLDGSVYVALTNNTGHGNFHGQIVRMAETDNNPAATSFEWSIFAVGGSQSGFSSPDNLVFDGEGNLWMVTDISSSRTNKGIYKFQGNNGLFFFRTSGPDAGIAFQFASGPVESEMTGPCWSPDGRTLFLAIQHPGEESKSLTELSSHWPIGGNEVPRSGVVAITGFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ24</accession>
    <name>A9AZ24_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="4" type="ordered locus">Haur_4432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4432"/>
    <dbReference type="EnsemblBacteria" id="ABX07064">
        <property type="protein sequence ID" value="ABX07064"/>
        <property type="gene ID" value="Haur_4432"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4432"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_4_2_0"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="211" mass="24096" checksum="C81584741A40BEB0" modified="2008-01-15" version="1">MAVRRVLQIEDPTDAVVLRAKAKRITSFDQSLAGLVDDMIETMREARGVGIAAPQVGVSRRVVVIEEPAQYEEHEDGTQTQIAPAVLYVMVNPEIIKASEETHMLQEGCLSLPGRYTKVPRNKWVTIKYYDLKGREQRLRHIPAEDYKVGHIAQHELDHLDGIMFTDRMTEESKLVDYRKESESARLKRRGLLARKKRPDAELESESTTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ36</accession>
    <name>A9AZ36_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">(R)-citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4444</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4444"/>
    <dbReference type="EnsemblBacteria" id="ABX07076">
        <property type="protein sequence ID" value="ABX07076"/>
        <property type="gene ID" value="Haur_4444"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4444"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_7_0_0"/>
    <dbReference type="OMA" id="KSWDFHV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4499-MON"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043714">
        <property type="term" value="F:(R)-citramalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="3"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="531" mass="57889" checksum="B37606E4EB0A17D4" modified="2008-01-15" version="1">MQIFLYDTTLRDGTQREGLSLSLADKLKIARELDRFGMHYIEGGWPGSNPKDAAFFAEAAKMEWKHAKIAAFGSTRRANSKPETDANLKALLDANTPVVTLVGKSWTLHVTEVLETTLEENLAMIRDSVALMKAHGKEVIYDAEHFFDGYRADNDYALATIKAAAEAGADWIVLCDTNGGSLPDWISAVVQRVKGKINTQLGIHTHNDSELAVANSLAAIVGGCRQVQGTINGYGERCGNANLISIIPNLQLKMGMFCVLPDQLQRLTELSRTVSEIANLNPDEHAAYVGNSAFAHKGGIHVAAVAKVEHSYQHIEPVQVGNRKRVVISELSGRGNIKMRAEELGVESTGLERGVLERVKLLESKGFQFEAAEGSFELLVRRAAADYAAPFKLLDVVTIVEQRRGVEMQAEATVKLQIGEEIYHTAASGNGPVNALDQAMRKALLSRYPELAEVHLVDYKVRILDSESATGATTRVLIEAAMGDERWTTVGCSENIIEASWQALVDSLELPLVRARSNQPVLLKHAATVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZB3</accession>
    <name>A9AZB3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03659">
        <property type="protein sequence ID" value="ABX03659"/>
        <property type="gene ID" value="Haur_1011"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1011"/>
    <dbReference type="eggNOG" id="COG3093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846681_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1028-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="37532" checksum="11DB3E723CF3705E" modified="2008-01-15" version="1">MDHRYQAYTFAELLRLFFERSRDEQINQNALAQKVGVAVPTLSNWFNGKYTPRFKDQVLRLAQALGLTALEADLMLCSIKQAWNTYGTPHDVLQKYTIVRYREELLSSRHSPSAADVSLATVYATWQLYFHDLFVGNNQHWGLGYKDDGVCRVERTITDGAYQLTLHNRFHNDVFIGGDSHCFAPPIYYLSVYAQRVAGESENDGFALIFEEMSDASHAIFRIRDQPQLASVISTRNGGDSFQIHLDRKRVPTIRPGEVNQLGMLVIHNQHRFFVNNSLIGSAEIERIPYSRLDVGIISQSMAPVICTFQDFRVYIPPNIYEQPECVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZB7</accession>
    <name>A9AZB7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1015"/>
    <dbReference type="EnsemblBacteria" id="ABX03663">
        <property type="protein sequence ID" value="ABX03663"/>
        <property type="gene ID" value="Haur_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1015"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_2_5_0"/>
    <dbReference type="OMA" id="GFGMSPK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1032-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="28"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="561" mass="59964" checksum="CD6C42F698BC816A" modified="2008-01-15" version="1">METAIKQAASAAVEFEQPRYTKRETLLTMLSVLLVMLLASLDQTIVGTAMPKVITDLHGFDRYTWVTTAYLLASTVMVPIYGKLSDMFGRKPLFIFGLIVFLIGSGLCGAAQSMNQLIIFRGLQGLGAAALMPIALAIVGDLFTPRERARWQGITGGVFGISAILGPTAGGWLTEHVSWRWIFYVNLPLGIIALLTLVFLMPTLGRKAQRVKIDYIGSILLVAGTVPLLLGFTWAGSQYAWLSAQVLSMFGLSIVFLGAFIAFEAWLERNNGQPIIEPSLFKNSIFRISVLITIISNMALFGNIFFLPLFVQGVIGTSITNSGLIMTPLMLTAIICSVVAGQIVAATGKYKIIAIVGMAISVLGGFLLLQLDINSTNTNVAIDMVVLGLGMGAGMSLYTLITQNALPNKIGQATSALTFFRSIGSTIALAAMGSVMNSAYLPAFKAAIPAEVAQNVPAESLAAFNNPQILLSPETQSLIQAQFAQGGQQGEALYNTLLGAVKYGLVDGIHHVFIFSFGITLLGFVVVFFLKEIELRGGRKKAEAQIEQTGEAGAAGMAAFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZL9</accession>
    <name>A9AZL9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05163">
        <property type="protein sequence ID" value="ABX05163"/>
        <property type="gene ID" value="Haur_2525"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2525"/>
    <dbReference type="eggNOG" id="ENOG50348KE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1282171_0_0_0"/>
    <dbReference type="OMA" id="LWFVPHL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2553-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="26560" checksum="0522C84D50FD2E1C" modified="2008-01-15" version="1">MQIVFLLMSGALLLLAVLLLWFVPHLLGQQEHRAKQETQQLKALLSDVLGEQEVVARRQAQLGSSLGHLQDQLETLHTSFPATVAKLAAQPADFSRPLIEHLDNRLNNLHCQLDGWMNERRQHSKQVSQQENESWAYLMSLLGTMQDQLGDVSQQRPRRPLREPQRVEFGSSAVVEDLRDEVESLRAISEEIAALQWRLRRTVASASKPNHPHNQQQPMSLLGANEPVRSVRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN1</accession>
    <name>A9AZN1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PBS lyase HEAT domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4453"/>
    <dbReference type="EnsemblBacteria" id="ABX07085">
        <property type="protein sequence ID" value="ABX07085"/>
        <property type="gene ID" value="Haur_4453"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4453"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_851984_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4508-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="35751" checksum="0FA65D668A61C14B" modified="2008-01-15" version="1">MLRPAILPLRDVQMQPIEQTETYSSAEMQALAQHPEVEQRQTIAYDLRFSTNPLTLAILIDLLNDPDQAVQINAIRSIGLWGARRNSPSLMQPATQALLALVQQSHEQMLLDHGLISLGEIGDQLSIDWCLSQLINQPRSRLCAATALGMLKAEKARPWLLTILADPCQASIVRTTCIEALSQLAFDLPTNQTLIAALQDSVAEVREKAGLALCKLGDFSAFKPIWAYIRLETAIKPSQVAHALALFGDQAFEPTLAFLNDPDPNLRYWAALALGMFHDSRAIPALIALLNDQAQTHTRAVVATAARKSLNRLQNLAVGNPDSTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU1</accession>
    <name>A9AZU1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Haur_4513</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4513"/>
    <dbReference type="EnsemblBacteria" id="ABX07145">
        <property type="protein sequence ID" value="ABX07145"/>
        <property type="gene ID" value="Haur_4513"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4513"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_3_0"/>
    <dbReference type="OMA" id="DAKYGEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4568-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="346"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ABX07145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="465" mass="49294" checksum="070BCE28EA6B42DF" modified="2008-01-15" version="1">MAQYDVVIIGSGPGGEVAALRAVQLGLKVAVVEKEQVGGVCLNIGCIPTKSLLHCADLLEETKEGKKFGVITGEVSFDLKGAMGHKEKVVKTMRTGLEGLFKKKKIDLFRGFGRLAGTNKVAVKGNDGTETVIETKNVILAVGSTPRALPFAPFDEQRIVSSTGALSLPEVPKHLVVIGGGIIGCEFASMYRTFGSQVSIIEMLPRIVATEDEEISAELAKAFTKRGIKLYTGSKTKAVNKRADGASVVFEGPDGKEQTLEADYVLIGTGRAPLTKNIGLEEVGVTIDERGYIPVNATMQTNIANIYAIGDVVPTPWLAHVASAEGVIAVEHIAGHHTNPINYDIIPSCVYCSPEVAHVGLTEAQAKERGYNVKVGKFPFAAVGKATAIGNRDGFVKIVADAEYGEILGFHMIGPRVTELVAEGGLALSHEATVESLLATIHAHPTLYEAMHEAGHALLDGTLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZU8</accession>
    <name>A9AZU8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4520"/>
    <dbReference type="EnsemblBacteria" id="ABX07152">
        <property type="protein sequence ID" value="ABX07152"/>
        <property type="gene ID" value="Haur_4520"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4520"/>
    <dbReference type="HOGENOM" id="CLU_2012102_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4575-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="14412" checksum="1C84EAD5A9440CF0" modified="2008-01-15" version="1">MQFSQQVFDYYLQYITAAWFGRNDLPPEDLSGYKAYVEELKLHLTKHHDEQIFKAALEESLTTDAVDYERYSGGTYPFEPEEVQAIMHYIYQTLWPEAELPAVAPPIKWLDLSVNQWFASKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV3</accession>
    <name>A9AZV3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4526"/>
    <dbReference type="EnsemblBacteria" id="ABX07157">
        <property type="protein sequence ID" value="ABX07157"/>
        <property type="gene ID" value="Haur_4526"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4526"/>
    <dbReference type="HOGENOM" id="CLU_1568610_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4581-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="19713" checksum="6734E1A9B0527D09" modified="2008-01-15" version="1">MNYYFFDQLTRWLERRGMDYTRPMQTNPQAADVHLRWVAPLPLIGKVTNDLAFWDFDRLAIEPEHQAYALEQANLAQLTLVEAGFARKRWLRLHLPSAITVAVSARRFSAECIKLVEQPFFAWTGGYSCSMILLNPRGYSIIHQRTWPRSSLPPKIAINFVQTMLKTLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B003</accession>
    <name>A9B003_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1062"/>
    <dbReference type="EnsemblBacteria" id="ABX03710">
        <property type="protein sequence ID" value="ABX03710"/>
        <property type="gene ID" value="Haur_1062"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1062"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_3_0"/>
    <dbReference type="OMA" id="YPIAYGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1079-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="287" mass="31994" checksum="198A8F603D19B7DC" modified="2008-01-15" version="1">MYNARTEQRRAWLQASPALIWLGFFFLAPLVLILIYSFQGRADDGTVLWNWSLANYQKLFADGAFWRTLWLSTWIALVVTAITLVVSYPLAFFMATRSPKIRGVLVLAVMIPFWTNFLVRIYAWKVLLGNNGVLNRFLGQFDLGPLQIINSPSAVIMALIYGELPYMILPLYAALERFDWVQLEAARDLGAGRFQTFWRVLLPQTLPGITAGSILVFVPTVGTFAVSDILGGTSVNMVGNTLSLQFGSASNWAYGSAISMIFMLLLLGAILLYFKATREVNDGENPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B068</accession>
    <name>A9B068_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2539"/>
    <dbReference type="EnsemblBacteria" id="ABX05177">
        <property type="protein sequence ID" value="ABX05177"/>
        <property type="gene ID" value="Haur_2539"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2539"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008466_0_0_0"/>
    <dbReference type="OMA" id="VNYDTPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2567-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="301"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="702"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1131" mass="128699" checksum="9EA6F6F4B22FE9AC" modified="2008-01-15" version="1">MQIPYVIDNIEQRLADVLRYLLSRASDQSLDIATAYFSIRGFEQLRHELETTGQVRLLLGDKPVAADDLGMRPDSSAFLRHELNAEAFTERTLRLVEQLIRFLRRDEVEVRLYTGLLAGEKGRRAFLHAKCYLLYGRLPAANVFDPLTPIVGIVGSSNFTGPGLVSNHELNLVHKTLLTDAELDDAEAKATVAQHAAQLSAAPLELEHERMLKSEIGTRAILDLSRWYEQQWQHALDYKEQLIELLENSKFGGREYSPYEIYMKALYTYFKDDLAERDQQPATRSAVELAEFQEDAVRKARRILAQYDGAIVADSVGLGKTWIGKKLLEDYAYHQRQKALVICPASLRGMWERELHSATIAAQVLTQERLGLDEFDGREFFDVDLILVDEAHNFRNKRAKRYQQLELLLAANGRRGRSGSRKKLILLTATPINNNIFDLYNQINLFTGNDRSYFASAGIGDLYKYFLAARCESLEAGSIRIFNLLEEVVIRRTRQFIRRAYPEALIHGEPIRWPTRQLHSVEYDLQAAYSGLYQNIIGSIEGLHLAHYNLEAYKLRPSDQDEFELGRQAALVGIFKSRFLKRLESSIEAFRISIRRSLAFVKTFAEYVQDGIVLDSVSFQQAMRLLEADEEDSDDSTPSSQASALDEHAAASLIIAKLPKLEASKYDRRRLHRALQADIDALNEIWHAIKHIQASHDAKLLQLQSLLASQLNGCKVVIFTYYKDTARYVYQALTEASNAEWLATLGNPTIRRIDSSVKTTDRTRIVSHFAPRASNQPELVGTSDEVQILIATDVLSEGHNLQDCGHLLNYDLHWNPTRMVQRAGRIDRLGSNFDLLHVYNMFPERELEALLGLVRSLTSKIDLINQTGFLDASVLGEVVTPRDFNTLKRIADEDHSVIEEQESFLELASSESLFAELQNVLATDAQRWLTDLDDGIHSGIERRNAKGLFFYFTAPRDGSTAHFWRYYDLEKQTITDNRYTIMQLIACSPDTPRFAPPYSEVDIFAIHDTILNSILRDVQQQVTATVVDKIVAPEQNVIAQLLHNNLAQPGVDRGEVRELRKMLKEPQVGAVVQRLRKTLNRYNADNDLLALLEVLRELYQTQGRSNLEPSGPVSMITRDDLTLVCYEYIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B9</accession>
    <name>A9B0B9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2590"/>
    <dbReference type="EnsemblBacteria" id="ABX05228">
        <property type="protein sequence ID" value="ABX05228"/>
        <property type="gene ID" value="Haur_2590"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2590"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_357072_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2618-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734459" evidence="3">
        <location>
            <begin position="24"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="94"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="711"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="785" mass="86940" checksum="01CBA851D78DB478" modified="2008-01-15" version="1">MRKHSWFTIIALLSLLWVLPAPAQSQSQDDKPKVVITHQVVTEKNALSVEAYFSVRYNDGRAVPVNEISSTVLDLKNGEPPVQAVPQDPTTPIKIALVMDQSGSMNPFIEEVKRAANQAIDQAPANAKIAVFTFTRMNSVDVYLPAFDFSDDRNAVKDYINQNYRSEPGGETCLYTAAHQATDFLLNTLKPEERRAIILFTDGKDEDINGNQCSDKTVIDVTTKAGPTQGTKTPIYTIGLCSADCARIQPESLRQISENTQAISLVGPRDQMSAAFITIMDSIKNQKYTSGFLRPCVETQVTLEVQLISGDTIAGIIPIGAHKCYNPTVSEAKIANLNPLPEKQKYSFNFTTTNTSPVNMVGVELQVLGPSQTLVYTEPIAVSISPQETKTIPMEMSDTKLTVAGNYTLHVLGYSSDGFTFRIGSPSERSEILATQAFAHSPIPITFEIRSNPVVDYETNTIRIDDVEITDEQSIIDPKFTYYKVRLFREDMQLFESERIQLDPTNPKIAIPLADIPQELIPTEQQSQLNLQIILETSNIQPIESPFKSFLFPVKPKEPFLKRYGVYVLIALVVIAIAAGFWYLWRNRKPKAGNVPMPYNPPTQAFNRIDLPGVNPASRQNANVPQQPQQQSAVRPAPHSAVNQPARPQSPVSNANASIPTAHFDGMQDNGATMIYNPPAAASRQQQLHVRVVQTPDPSQIQNKTITMFPCTIGRSEASVIVTGDKLLSRQHVEISLIGGQFYVADLSKNGLFINEQRQQANTPIQLRLPTTIRLGQDTYIELSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0H8</accession>
    <name>A9B0H8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
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        <property type="protein sequence ID" value="ABX07196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Haur_4565"/>
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    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3833">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_016047_1_2_0"/>
    <dbReference type="OMA" id="LSFGYWI"/>
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    <dbReference type="Proteomes" id="UP000000787">
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
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    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
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    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        <location>
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    </feature>
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    </feature>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="380" mass="40855" checksum="8D1700B9D94896AC" modified="2008-01-15" version="1">MANSSIAQPTSRKGLFARGRGAGRQLEWWQQLLLQAFCLTVAVSVLFPIMWIVTLSFKEAGSARPLKLEVIPPSLSSITLSSYQAVIEQPLSKSAGDISFWKLMGNSFFLAAGVSFFSVMIGVAAAYAFSRLNFVGRKLIFLSIGFILLMPGIATLAPLFAMLAKISTSLEVLRIIYFTMAGLLIAGLALMTISRIRSDDFRAGSAAFLVGGLAVAALFLWGGTQIEIPKNARPFELGRSLYGVGLAMISGALPFAIWNLKGYLDTIPKELEEAAIIDGASPNQIFFRIILPLATPALAVTAFLGFMAGWTEFALTARFINKADNYTLAIALQTMTGQYATVSWSNFAAMSIMISLPVSIVYLALQKYIVGGLTLGGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1186"/>
    <dbReference type="EnsemblBacteria" id="ABX03834">
        <property type="protein sequence ID" value="ABX03834"/>
        <property type="gene ID" value="Haur_1186"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1409">
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    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
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        <property type="entry name" value="Metallophos"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="32549" checksum="4AB19612D082CE4C" modified="2008-01-15" version="1">MASTILHLSDLHAGPPFNPEKAQQILEAAWQIKPTLTVLSGDFVQRADIRSQWLTIRDFVAQLPQPTIAVMGNHDVPLYNALYRMLRPNYYYKKYISPILEPVWGNDDFVAVGVNTTRSFTVDGGKLTDQQLLELERSLARYPDSLCKIVVMHHHPVMPPGETRDVIQNAAAALRTFDRSNVELVLCGHTHASYIGNTLEFDPDLRQGTVIVQAGTATSRRGRRWYRGKNAFNVLEIEHMRSVITQYLYLEDAGRFLPVSQHQFPRRSAGAYALPLNEAVLEIVEPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B101</accession>
    <name>A9B101_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2641"/>
    <dbReference type="EnsemblBacteria" id="ABX05279">
        <property type="protein sequence ID" value="ABX05279"/>
        <property type="gene ID" value="Haur_2641"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2641"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_117133_0_0_0"/>
    <dbReference type="OMA" id="EADCLYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2669-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="159" mass="17835" checksum="6FCAA8366185C929" modified="2008-01-15" version="1">MQIREAAVDEHSQALEIIRQAFVEYEAILDPPSSVGWETVESFRSRMGDGGVLVVESHNQLIGCVLYERRGSDTLYLGRLSVLPAYRGRGLAKQLIVAVEAIAQAEQRQIITIGVRLALPHLIAMYQQLGYIITEYHSHQGYPEPTYVTMQHQLRTTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B180</accession>
    <name>A9B180_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4636"/>
    <dbReference type="EnsemblBacteria" id="ABX07267">
        <property type="protein sequence ID" value="ABX07267"/>
        <property type="gene ID" value="Haur_4636"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4636"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_2_0"/>
    <dbReference type="OMA" id="TMEFESF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4693-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="138"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="442" mass="45535" checksum="DDE3C3789DC9A72F" modified="2008-01-15" version="1">MAKKLEMPKMGYDMVEGTLAKWLKKPGDEVSRGEPIAEVETDKVTIEIEAFEAGTILKFLVNEGETVPVGAPIAEIDDGSGDDEAEAANASVTPSSDAPAVGEGGEAAPPAPAVVAQPEKVEATPAASAPATSTGRLFATPAARGLAEQRGVDLAGLKGSGPDGRIVKADVLAAAVAPKAAPAATPAAAPAAAQAAPVASPVPAPVGLIFAPPAPNSVYTEEPLSRLRQTAAKRMVESQQQVPPFFVTSTIEMDAIQALLPKLREAHGGKLSVTELLLKACAIALKKFPALNSTFAGDKLLVHKDVHISVAVATDAGLLAPVVRNCDSLSLGAISNQMRDVIGRTRDGKAGLDDLQGGTFTVSNLGMFDVTNFIAIITPPQSAILAVGSTIATPVVRDGEIVIRQLMNVTVSADHRATDGASVAQFLVELKNLLQNPFKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A4</accession>
    <name>A9B1A4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S10 serine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4660"/>
    <dbReference type="EnsemblBacteria" id="ABX07291">
        <property type="protein sequence ID" value="ABX07291"/>
        <property type="gene ID" value="Haur_4660"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4660"/>
    <dbReference type="eggNOG" id="COG2939">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032786_0_0_0"/>
    <dbReference type="OMA" id="TATAWYH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4717-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="PTHR11802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="494" mass="55828" checksum="2E563D93B45F6E3E" modified="2008-01-15" version="1">MADAGSAEKRSDSESPKPPQEIVSVTHGRVKIKGNDVPYTATAGTIVLYEDDPEFKQAPKAKATVFYVAYTRSDVDDQTTRPITFSFNGGPGSASVWMHLGLLGPKRVLMADETGNLPAPPFRLVENEYSLLDQSDLVFIDPISTGYSRAATGENPNQFHQFTKDIESISDFIRLYTSRAKRWLSPKYIIGESYGTTRGSAITNYLQNRYGMYLNGIMLISSILDFQTVEMDPGNDIAYVVILPTYAATAWYHNKLDAKLQLSLSDTLAEVEAFAAGEYATALLQGDSLAEGKRRSVVRKLARYTGLSERFIDHSNLRIDLMRFTKELLRDQQRTVGRLDSRFVGIDRDPTREAFEYDPSYAVIHGPYSATFNDYVRRELKFESDEPYEILTSKVRPWKYDKHENQYVSVTEALRSAISQNPYLKVFVASGFFDFATPYYATLHTFNHLGLDQTLRNNIVIKHYEAGHMMYTHLPSLAELKSDLEAFISQTKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1H1</accession>
    <name>A9B1H1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate (FAA) hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1208"/>
    <dbReference type="EnsemblBacteria" id="ABX03856">
        <property type="protein sequence ID" value="ABX03856"/>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-1230-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
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    </evidence>
    <sequence length="342" mass="37336" checksum="41CDBA2BAE22634D" modified="2008-01-15" version="1">MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDAAIQVVSAVVDLLGGGGDGIEWDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDFYAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPDSDLVMPRTSQLDYELEIAAVIGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLDEIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGTVGTGCLLETTHGEGPWLEVGDVVELEIERIGILRNTIVDRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
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    <name>A9B1H6_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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        <property type="gene ID" value="Haur_1213"/>
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        <location>
            <begin position="9"/>
            <end position="30"/>
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    </feature>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX03861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="29433" checksum="6CF174BC2E02B76B" modified="2008-01-15" version="1">MASLRVGHWVWVGYLFVWAWSVPLLAFDLVPAGGEFMATVMLVVPGGLTAWWLIQRYGKLGWLSSIIIAVGSWLTEHLGVTTGWPFGAYQYNGVLLPEIVGVVPLAIPFAWLLVVPGALELSRMLMPKVGFWPTVLGAASLAMLFDLVIEPVAVYVNRYWTWLETGPMFGIPTANFVAWWGLAFILALATEMLGQRTNNLPQSPKLNLPIAIYLLNLALFTIVNLTHQQLAAGALGLLLLAGFGWRLHQRQIGWHWRYDQLIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R8</accession>
    <name>A9B1R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c assembly protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ordered locus">Haur_2722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
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        <property type="protein sequence ID" value="ABX05360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2722"/>
    <dbReference type="EnsemblBacteria" id="ABX05360">
        <property type="protein sequence ID" value="ABX05360"/>
        <property type="gene ID" value="Haur_2722"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2722"/>
    <dbReference type="eggNOG" id="COG1138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015041_3_0_0"/>
    <dbReference type="OMA" id="SYWGMQL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2753-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
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        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
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        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
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        <location>
            <begin position="119"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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    </feature>
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    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="489"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="4">
        <location>
            <begin position="91"/>
            <end position="295"/>
        </location>
    </feature>
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        <location>
            <begin position="400"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="781" mass="85277" checksum="4C53D5BBDF64B621" modified="2008-01-15" version="1">MNLFMFGTLLLVVALVAAFTATTSYTLLIAGQRTALSWGRWSVRIAAVSILVASLLLLALFYFGRYEFDYVYNYSSNDLELRYKLSALWAGQQGSFMIWALVGLLAAPLLLRRSREFEPFVLMPLMAVQVAIISFMLINNPFALRFDVAKQIIYAEDGRGLNELLHNPWMVIHPPILFLGYGLLAIPFAYAIAGLWRRDYDGWVKAALPWTITAWVILTTALTLGGYWAYETLGWGGYWAWDPVENSSLLPWLTVTALLHGMLVQRAHGGLRRANFSLAIVTYGLVMYASFLTRSGVLGDFSVHSFTEDGLGTTMAAVLVVGLVVSLGIFFQRWRDVPINKLSESLFSRDSLFVLGMFCLVIITLIVGLGTSMPLFSKTPILRDGLRTTFAKAFDIAASQDGRFSLQPSFFRTVTPPFGLVVIGLMTIAPLLGWRGGNMRKFIFALRMPAILAVVATVVGLLLGVRKPLSLAYLGLGSLGLGVNILMIVRTVRGGWMRIGGYAAHIGAALLVIGFVGSSAYSSPDINMTIPLNTTQTAFGHKITFEGYATRTNNQGAEKGVIDLAVQRGDGEIQDAAPQLYLNPRDGQWISNPAIIREWWGDLYISPGKYLAASNPNLLTLAQGQKGSVGPYSFVFQNFDYSLPEGHSGAEAQTDEITIKARLTFYDEAGNATTIEPGLRAVANVGNQPEPYTLADGNQVLISALSLENRQVELQIVGLDLPVLPERADIFVSTKPAVGLVWVGTVVMTLGGSLAATRRFIEHATKRRAQASVPEAATQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B282</accession>
    <name>A9B282_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4801"/>
    <dbReference type="EnsemblBacteria" id="ABX07432">
        <property type="protein sequence ID" value="ABX07432"/>
        <property type="gene ID" value="Haur_4801"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4801"/>
    <dbReference type="eggNOG" id="ENOG502ZVNV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2409956_0_0_0"/>
    <dbReference type="OMA" id="TILAREF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4860-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="96" mass="10061" checksum="53CF014AE516C68E" modified="2008-01-15" version="1">MEFSVIGLLLMLLIAAVCGAAGQAIAGYSMGGLLASIGVGFIGALLGSWLAANLGLPELLTFNVEGKPFPIIWSIIGATLFALLISFMRAPRRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B294</accession>
    <name>A9B294_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4814"/>
    <dbReference type="EnsemblBacteria" id="ABX07444">
        <property type="protein sequence ID" value="ABX07444"/>
        <property type="gene ID" value="Haur_4814"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4814"/>
    <dbReference type="eggNOG" id="ENOG502Z81A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_733146_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4873-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="40824" checksum="FFA16940608512C5" modified="2008-01-15" version="1">MRQYLDRYVKPLWQTYSSPGQPLRPTNTRALHTIYGIWLFAFVLKLMGSGWDVAWHFRFLRDDLAPPHMINTVGTIIVIMLVMFHTWTGYGVDRLTLRLMQAGISIFLIAIPLDLINHRLFGLDITSWSPTHALLYLGTAVMLLGVLRGWLLLTPESPIKTVFGIGFWAFLLEDFLFPLGQQEYGVTAIEAMRIGKPYADAELLLEAGANPERFAIPVPDWLYPLWLITSLVLVLVAARLIMRGRWTATLVAGSYLLYRVVSFYILRGMEFPPSFVPIFFIGTALAIDIGITYRINPFVAAFGTLFMFYAGAWISDQITLMPVVPAYTIPVAIILLCTIWVGALWIERSPYVERWRTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F3</accession>
    <name>A9B2F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1353"/>
    <dbReference type="EnsemblBacteria" id="ABX03998">
        <property type="protein sequence ID" value="ABX03998"/>
        <property type="gene ID" value="Haur_1353"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1353"/>
    <dbReference type="HOGENOM" id="CLU_952400_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1374-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="292" mass="33051" checksum="E7D48F028FDCD327" modified="2008-01-15" version="1">MTKFRGAIEYEKPPPDEHNDIQNLITNFRRLNNMFIAVSFVHMAFTMLAFTHGLVGFAWFIVACATMAMVLGIDLALMWLSAYIGIQLKHKQPIGFWNWLAFIIALAVEVTFNTASLIIHMPPSMGFFGYLIAGTFGSFVALIIYASATAPNRLRQTIDYIKHLERVDAENERKRLEAQRKQQRQTAMQERFEPSESHNETIAMLPEPDESAALRTTNGKSAISADDIHAILKVLYEKNITEFKTKQDLRRLLGFTSTSSGTKAFDTLQRYAMVEAGESGYEIIWENANAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L8</accession>
    <name>A9B2L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2831"/>
    <dbReference type="EnsemblBacteria" id="ABX05469">
        <property type="protein sequence ID" value="ABX05469"/>
        <property type="gene ID" value="Haur_2831"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2831"/>
    <dbReference type="eggNOG" id="ENOG5030SMY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2537945_0_0_0"/>
    <dbReference type="OMA" id="RFRYIPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2862-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="83" mass="8888" checksum="1E2A3505E9D4378C" modified="2008-01-15" version="1">MAAPIDRAQILEALRTADTTISCYLDLESGSVISIDDTAADADTEAKRNEIMEGYGERFRYISGGQTGADDAAVQTWLDGEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N0</accession>
    <name>A9B2N0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2843"/>
    <dbReference type="EnsemblBacteria" id="ABX05481">
        <property type="protein sequence ID" value="ABX05481"/>
        <property type="gene ID" value="Haur_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2843"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2874-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14468" checksum="DC40B1EB548808A8" modified="2008-01-15" version="1">MANILAIDDSGLMQAFWVRILSRSQHNVITVSSGDEMRGVLATMNPQLIFLDLSFPGENGFELLQHIRSYQHCLEIPVIAVSGYAGEDTRQACREAGFTDFLAKPFSLAELRGMLARYLDHATNPRALAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B347</accession>
    <name>A9B347_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4880"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07510">
        <property type="protein sequence ID" value="ABX07510"/>
        <property type="gene ID" value="Haur_4880"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4880"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_0"/>
    <dbReference type="OMA" id="FAWQERD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4940-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="19"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="393" mass="43109" checksum="DF7D3BE1B89F0CED" modified="2008-01-15" version="1">MRIVALAPFGLRPKATLSRRALPMLQAAATRGDDVHVLAPSDLYPADAGSTSVIKQITVEHGPAFGQGSAAMLRSVSWMLKRCLALQPDLVHLFKPKGYGGMALPLIRRLRPKLPIFVDTDDWEGTGGWNDRLDYPRHIKMMIDWQERNLPKLADCVTVASQTLANQVILFGLPTNKLLYLPNGVDLPRRQLPERSLARAQLGLTQDPIILLYSRFWEFPVSDVVAMMVGVLAQIPTAKLLVIGAGEHGEEQQLTLLAQRAGINQALDNRGWSEQSTIDAALAAADIALYPMDDTLLNRAKCSAKLTEQMQAGLPIVAAAVGQVAEYLDQTSAVLVEPSNSGALAQAVIQLLQQPQQRQSLGRVAQARIEKLFNWPAQSQTLLQRYDACYKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B0</accession>
    <name>A9B3B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1429"/>
    <dbReference type="EnsemblBacteria" id="ABX04073">
        <property type="protein sequence ID" value="ABX04073"/>
        <property type="gene ID" value="Haur_1429"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1429"/>
    <dbReference type="HOGENOM" id="CLU_1728850_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1451-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="151" mass="17873" checksum="FD08BC99639B6A79" modified="2008-01-15" version="1">MHVRLWNRLRRFSLTDLYALMIIIFIVWQFGSMAFYQIFGVETFIDWQPIPLYPPHVEPVVRSETPTEQSLRFTTADSVEDIVEWYDNEFNPKTRRQYDRVVEDQTPVALRIKYQFCTGMAITLNVTSDQTIKEVSLVQHKYSPRDGFCSP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-08-10" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R2</accession>
    <name>LON2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lon protease 2</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-dependent protease La 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lon2</name>
        <name type="ordered locus">Haur_2996</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="1">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B3R2"/>
    <dbReference type="SMR" id="A9B3R2"/>
    <dbReference type="STRING" id="316274.Haur_2996"/>
    <dbReference type="MEROPS" id="S16.001"/>
    <dbReference type="EnsemblBacteria" id="ABX05634">
        <property type="protein sequence ID" value="ABX05634"/>
        <property type="gene ID" value="Haur_2996"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2996"/>
    <dbReference type="eggNOG" id="COG0466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_3_0"/>
    <dbReference type="OMA" id="VLDCVPM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000396574" description="Lon protease 2">
        <location>
            <begin position="1"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="3">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="601"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="688"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="731"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="365"/>
            <end position="372"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01123"/>
        </source>
    </evidence>
    <sequence length="815" mass="90406" checksum="979C3FE5B4B20427" modified="2008-01-15" version="1">MADDRQLVDEISAATTLELPVLPLINTVLFPTMVTPLFVARELSMAAIEAAMSADRQIVAVAQRAIEIEEHDTSQLYQVGVIAHIERVLKLPDGTTSVLVQGQQRVQIVDWLATEPYINAQVQIIEPDHESSLAIEAMMRGVLASYEKVVKLSRTMPDDAYVAALNLEDASALADLIASTLPLDIVRRQQLLELFEVEERLRRLSVVLSQEIDVLELEHHIQNQVQKEVDKSQRDFFLREQLKAIQTELGQEDPLTRELNELHDRIVAANLPAKAQAKALEELGRLEMMPPAAPEYSVIRTYLDWLLELPWSKTSADVADLEVAAKVLENNHYGLKKVKERILEFIAVRMLAGDSTKSPILCFVGPPGVGKTSLGRSVAEALGREFVRLSLGGVHDEAEIRGHRRTYIGAMPGRIIQTMKDAGTINPVFMLDEIDKLGNDFRGDPAAALLEVLDPEQNNTFADHYLDLPYDLSKIMFITTANMLDPIDEPLLDRMEIVELPGYIEEEKVQIARKFLIPKQIEANGLKQHPITISDEALRQIIRTYTWEAGVRNLEREIGGICRKIARRVAEKKRYPRRITPTMLTDFLGQPPFDYSRANDRDEIGVATGMVWSSNGGDVVAIETAIVDGKGTTTLTGQLGDVMQESAQAALSYARASSRRLGIDGKRFEKIDIHIHVPEGGVPKDGPSAGITLACSVISALTHRPLRRDVAMTGEITLRGRVLPIGGLRDKILGAYRAGITTMLIPKKNLRDLEEVPNNVRRQITVVAVEHMDEVLPIAFVSNPLERGSQHTSDGDQTSVVLPTITQPQLGSVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U8</accession>
    <name>A9B3U8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C2 calpain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3448"/>
    <dbReference type="EnsemblBacteria" id="ABX06084">
        <property type="protein sequence ID" value="ABX06084"/>
        <property type="gene ID" value="Haur_3448"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3448"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768974_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3485-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="2">
        <location>
            <begin position="149"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="360" mass="39874" checksum="80447992D9596AE4" modified="2008-01-15" version="1">MPAPIVLIDYEQIDQQSQRFQRQAEIVSQLHQQLNQTYQQLQVDWHGTAAKAFFDEMQTTIFPSLSRLKEGLITAQQVTLNVNSILREAETEAASLFKGAFDGISLPVIGTYRNPSANIPTLTNLEYRRLEHPVFAQGAGDSNAIAMDDVKQGLLGDCYLMAGLAAIAKTNPDVIRKAIRDNGDGTYTVTFHPEAESGIKKIFGMRSTVEVTVTNEFPHTKGAIDPAFAKLSNDSEMWPMLIEKAYAKYKGGYANIELGNAGEFIELLTGNDSVHTNVADVDFATLKRQVDQGDAVTTGTPDKLNNPPQFVSEDHAYVVQHVDLNNKTVTLYNPWGTEHPTISFDEFKANYEQVAVNEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3V0</accession>
    <name>A9B3V0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycine cleavage T-protein barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3450"/>
    <dbReference type="EnsemblBacteria" id="ABX06086">
        <property type="protein sequence ID" value="ABX06086"/>
        <property type="gene ID" value="Haur_3450"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3450"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_6_3_0"/>
    <dbReference type="OMA" id="RHHELGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3487-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCV_T" evidence="2">
        <location>
            <begin position="6"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="3">
        <location>
            <begin position="249"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="35730" checksum="ACA59265C398C5CF" modified="2008-01-15" version="1">MNEQAYRAASEHAVYLDRSSAGCIEITGRDRLVLINRLSTNAVLNLALGTGQITVLTTNIGRIIDLITVFAIDDDTIWVITSANRGAQLTTYFGRNKFYGDQFKVRDVTESVHQMRVYGSQATAMLERLTSQSLEHVGLWQHLSAEIDGCPVRLARIRPMRGAGWAIFADLAAADALCEAFDDANAALLDRPTYHTLRVEAGYPALNELNEEFIPLEANLWDAVSFNKGCYIGQEIIARMDSRGRLAKKLQGLGLSGAVEVPATLTKNGQDAGTLTSVVWSPALNQYIGLGYVRTGHELGSELTIGEQQATVVELPFIAQTEPTTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X9</accession>
    <name>A9B3X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06115">
        <property type="protein sequence ID" value="ABX06115"/>
        <property type="gene ID" value="Haur_3479"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3479"/>
    <dbReference type="eggNOG" id="COG5513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1747135_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3516-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734545" evidence="1">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="15812" checksum="39D0CB14500C38F5" modified="2008-01-15" version="1">MRKGFLLLVLTSVLAACGTAESTPTTVPTATVAATPTTDSAAYPTPDLAQSEINPMMIESVAVSVKESMPPQVSVEINGMLNDGCTSFHEAKQSIDGNTIKIEVTTIRPKDAMCNQQISPFSTIIQIEGELKPGEYTILVNDVAEALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y8</accession>
    <name>A9B3Y8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3488"/>
    <dbReference type="EnsemblBacteria" id="ABX06124">
        <property type="protein sequence ID" value="ABX06124"/>
        <property type="gene ID" value="Haur_3488"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3488"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105789_1_0_0"/>
    <dbReference type="OMA" id="GWTIRQV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3525-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="18121" checksum="676FDFFE78C4EA43" modified="2008-01-15" version="1">MSEQRDQWIAQIEQLPAQLTELVRPLSPSQLTTQFLANEWSVAQNIHHLADSHMNSYIRCKLIASEENPTLKPYDQDSWAAFGDAQQADVEISLQLLRSLHARWVQFWRELPEDDWQRTGFHPENGPVSLISLVETYANHGLGHIDQIQRTLAAEPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4B3</accession>
    <name>A9B4B3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0018"/>
    <dbReference type="EnsemblBacteria" id="ABX02670">
        <property type="protein sequence ID" value="ABX02670"/>
        <property type="gene ID" value="Haur_0018"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0018"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_12_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-18-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="22125" checksum="AB814C6EF89D5F84" modified="2008-01-15" version="1">MSNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVEDDSRDMSDLLRQVGALPNLWQGLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLVRQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIMLIDGLTWRKGLYPEHDLTLYAAGLKHTIKYLLSGTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4M0</accession>
    <name>A9B4M0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1542"/>
    <dbReference type="EnsemblBacteria" id="ABX04185">
        <property type="protein sequence ID" value="ABX04185"/>
        <property type="gene ID" value="Haur_1542"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1542"/>
    <dbReference type="eggNOG" id="ENOG502ZISD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2669130_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1566-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="8594" checksum="9FABC58FBE2DBC37" modified="2008-01-15" version="1">MKQRFPRHQKMTIVHGILSIVLIIDIVQLWLLIATMNSYLGGDSGVPLPALIFSCICLLLNLGLLRFLYKLDRTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W6</accession>
    <name>A9B4W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3051</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3051"/>
    <dbReference type="EnsemblBacteria" id="ABX05689">
        <property type="protein sequence ID" value="ABX05689"/>
        <property type="gene ID" value="Haur_3051"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3051"/>
    <dbReference type="eggNOG" id="COG3845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_0_0"/>
    <dbReference type="OMA" id="VGREMSH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3083-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="261"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="511" mass="55257" checksum="BBE15CEA5EA42D46" modified="2008-01-15" version="1">MTANVVPALEVRNITKQFPGVLANDQISFTLLPGEIHAFLGENGAGKSTLMNILYGLYDPDQGEILINGELAKIKNPADAIRLGLGMVHQEYALVDTLTVTENIILGTELRNGPILNAKEASQRVRELSEQYGLAVPPDAIVGDLPVGVQQRVEILKALYRNVNMLILDEPTAVLTPQEADDLFRVMRELADQGKALIFITHKLREVREVADRITVLRRGKVVGGADPKTASEGQLAALMVGRDVVLKVDKTAANPGDAVLKVRNLKLRDDRGLTVLDDVSLDVHAGEVLGIAGVQGNGQTELVEAITGLQHLPTGSIELLGKDITNRPPRSITEQGVAYIPEDRKGTGLVLGYSIRDNLVLSTYYKAPFTKGLTFNDAAIDENAKELIETFDVRTPSATTTAGSLSGGNQQKIIVAREFTRENRLLIASQPTRGIDVGSIEFIHNQIIKQRDAGLAVLLVSAELDEILSLADRVAVMYHGKIVGILPIAEATRERVGLLMAGIQEQPNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X2</accession>
    <name>A9B4X2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiopurine S-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.</text>
            <dbReference type="EC" id="2.1.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.67" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3057"/>
    <dbReference type="EnsemblBacteria" id="ABX05695">
        <property type="protein sequence ID" value="ABX05695"/>
        <property type="gene ID" value="Haur_3057"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3057"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085515_1_0_0"/>
    <dbReference type="OMA" id="LWCGDFF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3089-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00812">
        <property type="entry name" value="Thiopur_methtran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025835">
        <property type="entry name" value="Thiopurine_S-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023956">
        <property type="entry name" value="Thiopurine_S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="216" mass="24798" checksum="167B85A78E696AE2" modified="2008-01-15" version="1">MEATFWINSWQQGGSATSFHRRDIHPYVEHFATPEFLQGKRVLVPLCGKTNDLRWFSQYAEAVIGVELVTTAIEQFFAEQELDYVQPDPTTYVSGNITILNRDVLSLTTADVGNIDLVYDRAALVALPHEMRNQYRATIDQLLPVGGQQMIITLEYAPLMATPPFSITPTEIEFYYGERYFISHFAAPSQPEHRMVAKFNLQFLKEHGFLITRYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B534</accession>
    <name>A9B534_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3535"/>
    <dbReference type="EnsemblBacteria" id="ABX06171">
        <property type="protein sequence ID" value="ABX06171"/>
        <property type="gene ID" value="Haur_3535"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3535"/>
    <dbReference type="eggNOG" id="COG3176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058962_0_0_0"/>
    <dbReference type="OMA" id="YLRLGAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3572-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="29581" checksum="43253E02BA38258F" modified="2008-01-15" version="1">MTLATISSTTPRLTVKCATTSAEIEQALRLRYRVFVEEANNSRLWNDHGLEYDVFDQWCDHLLVIDQNCDQVVGTYRLLPGERALAHQGFYSQTEFDLAKFSHLANALELGRSCIAADYRGTRAIQMLWGGIANYLAERPHSHLIGCASMNHDELPDVSALYSMLRQHNVITDRYHVQPLASHRMADLRCLPMTCSEREMVRRLPPLIKGYRWMGAELAGEPAYDPLFHTTDFFVVFETSQMTKRYQRHFASSYQATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>A9B537</accession>
    <name>A9B537_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">accA</name>
        <name evidence="12" type="ordered locus">Haur_3538</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3538"/>
    <dbReference type="EnsemblBacteria" id="ABX06174">
        <property type="protein sequence ID" value="ABX06174"/>
        <property type="gene ID" value="Haur_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3538"/>
    <dbReference type="eggNOG" id="COG0825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015486_0_2_0"/>
    <dbReference type="OMA" id="TPWQRVQ"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="278" mass="30277" checksum="9E235AE4C3FAC962" modified="2008-01-15" version="1">MTTLTELLPWDKVQIARNPQRPRTLDYIRVLCEDFFELRGDRHHGDDQALVCGISKIDGRSVAIIGHQKGSDTKENVRRNFGSPHPEGYRKALRVMEHAKKFNMPILTLIDTAGAHPSMAAEERGQAEAIARNLLVMADLPVPIIATVIGEGGSGGALAIGVADRLLMLEHAVYSVASPEASAAILWRDSSKASEAAKAMKITAQDLHSFGIADTIIPEPEGGAHMDVPVILQAVASALREQITTLSTLTIDQLLEQRYAKYRAIGRFRQAQTTLVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B559</accession>
    <name>A9B559_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3560"/>
    <dbReference type="EnsemblBacteria" id="ABX06196">
        <property type="protein sequence ID" value="ABX06196"/>
        <property type="gene ID" value="Haur_3560"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3560"/>
    <dbReference type="HOGENOM" id="CLU_1452587_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3597-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="172" mass="19438" checksum="EDC65025D095B4FE" modified="2008-01-15" version="1">MKQQEQSTTNGQSLEIFFFKRTVINQFEGPNQNPTTALQTIDLAEASIVLNQTDLVDYNWPQQQLRIRNPQGVLAKDRPAEMDIEGFFVLVFNQQRIVMGRVRSNSTAMAADYPLLLDTIESYSNQQAISVYQLRSNSGTIRSDAPHSFPNPDPTIGEAVKEHLRQLGKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B580</accession>
    <name>A9B580_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3581"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06217">
        <property type="protein sequence ID" value="ABX06217"/>
        <property type="gene ID" value="Haur_3581"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3581"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_0_3_0"/>
    <dbReference type="OMA" id="YASCPAI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3620-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="183"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="378" mass="41180" checksum="33142B20CC782779" modified="2008-01-15" version="1">MHVVQVIDSLYRGGAQQLLVTFAIEAQRRGIKTSVVCLKDEDRGSNLVERLNGLGVEVLRLAAPKMLAPKRIWQLTRWLRRNQVSVVHTHLTYGNVVGILAARLANIPVVATMHLAGFDPSIANRQQQFEAQVVQRLAQQIIAVGYTTRDAYQPIMPNRQLHVVHNAVVAVPEISPEQRQTTREAVLGDPNLTMLINVGRFAAIKDLPTLIDAFALVHAQHPQARLVLAGEGDQRPKIEAKINAHQLPAVVNLLGARDDIPVLLRSADLFVNSSANEGLPIAVLEAMAAGLPIIATKVGDVPHVVREQAGITVAPHDHQALAAAINQVLSEPSQIQAMQQAAQQIIEQYHSPSAWVDQLLSLYTAAHEGVDQREAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B596</accession>
    <name>A9B596_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 type 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3597"/>
    <dbReference type="EnsemblBacteria" id="ABX06233">
        <property type="protein sequence ID" value="ABX06233"/>
        <property type="gene ID" value="Haur_3597"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3597"/>
    <dbReference type="eggNOG" id="COG3103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_677517_0_0_0"/>
    <dbReference type="OMA" id="RSIDGEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3636-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="342"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="406" mass="42401" checksum="85B717C45A615C76" modified="2008-01-15" version="1">MSQVALTPRSQPTTVWQLRRKKVPDQLSLPADYVPTDYTSLPTPEEPKKGGGLGMILVVVVLFLALGAIAYAVWGQGSGEEDVVPTKVPTTALTIDRASMIVSDGKLTAQISITTDAPDESQVGAILLEDGRPFEFFDTDAMTTTVSGGKARLIIPEMEGHEDGRKSSEYTVQVTVASADGDVLAKADEAIEIKGDALDRFLGDTAVTPIDVTPTITDPISGTMVPTPADGSTPVTQVTPVQPTAAPGGLPVPLDNVVISRPGIVYTTPFGPANQRGNVTAGEIARIVVKMPVNGEVWYLVAISQSGQSGWLNSSTIDLPATEVNKITPVSGDAPFAVAFNGGNVRSAPGGDVLTQVDAGVNVSLINRSSDSAWFKIKLPNGSEGWVVGQILTINPAVLNTIPVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C6</accession>
    <name>A9B5C6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0099"/>
    <dbReference type="EnsemblBacteria" id="ABX02751">
        <property type="protein sequence ID" value="ABX02751"/>
        <property type="gene ID" value="Haur_0099"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0099"/>
    <dbReference type="eggNOG" id="COG3372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_544884_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-100-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008508">
        <property type="entry name" value="DUF790"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39640">
        <property type="entry name" value="PTHR39640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05626">
        <property type="entry name" value="DUF790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="500" mass="56232" checksum="FCEE22E718F0505C" modified="2008-01-15" version="1">MSFTPADFKYTSRTGELGRQLYPHQLRDDRYLAAIDYAIGYYEQMLGRARREFEAATLLEFFGDPKLARGLVACLSQTYRWHQPQLAEVLDQPTYAQLVERGLRNSADFRALLYAHANQTHGFILPSERWPAVSQLAAELGLTPSQFERVLYLDDEQEALLVRSAERPEPSAIVALYNFHSLETGLRNCRSLQLRLDGDINALAVSAHNLAQRYNLRYELSEPEDCIATFVTLTLHGAKDALGNWTRTGRRIARCALRLLAAHPNAASEGLIQVHMQGKNSLIKLAKRELTVLGGTARQQPDNLGDSWETTLEQQFSQAWSRLVSKSQNAGWRIRRDPVPFSLAHRLLVPDFIAQRGSERIPIFVPATEAMAASLAQRLVGQPKVLVVIAKSYQNLLRNCQVAKVMYQTTPDMLTVLAQLEQLTPAQAPLDRWSRLALRFDQAGFVAETELLEILECRNPVEISLALRGWREGTAQYVPNLGLFTPQKLRELGSMLGKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H5</accession>
    <name>A9B5H5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0148"/>
    <dbReference type="EnsemblBacteria" id="ABX02800">
        <property type="protein sequence ID" value="ABX02800"/>
        <property type="gene ID" value="Haur_0148"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0148"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_12_1_0"/>
    <dbReference type="OMA" id="RHVHLSI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-151-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="302" mass="32631" checksum="56498C5EFC70AD59" modified="2008-01-15" version="1">MEQSIVVFGDLNLDTSVSIGQFPLHEGDTLFSFDGISDAIGGAAANVAVGLTALGHQVHFGSVVGQDRMAELVQQLAQAKGLATNSIRPDWPTTSRTVVLIDAAGNRQCINDPKAVHRYRYPEAALPTLFEQSQWVYCSTQNWCRYVAQAARDAGSTVIVDVQALVDIDEYHRDFLQAASIIILSTEQLAMHSHEFMRRLWQQFEIDIVVATHGNHGATLGVRATNTIEYQPAFELGSVVDKTGAGDAFCAGFIAGLASDLTPRQALSFGQYVAASKIAIKGSTNGFPERTHVLQALAQLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5M4</accession>
    <name>A9B5M4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1614"/>
    <dbReference type="EnsemblBacteria" id="ABX04257">
        <property type="protein sequence ID" value="ABX04257"/>
        <property type="gene ID" value="Haur_1614"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1614"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_709350_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1638-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="389" mass="40688" checksum="591BD487C0A4471C" modified="2008-01-15" version="1">MSSTVQQLIQQGVQAARAGNHAEARLVLRQAITADPQNEQAWLWLSAVEATNGEKIAALQQVLAINPANAAAKRGLDLLKPTQIDFANLGQTSTAAPAKASFSPPPARAAGNASLLQPRPNFEVNSPASPISQEFGTLASATPAPIPAQTLETPAVQATVAETKPTPEPTNAVNYNNDLVGSLRPAIAKGPKKRSVLPTRSELIISAILLVLLIGGFNLVRSALAGRLGGLRGSDEISASERATSQALIGWNANVPTPVVEVITDSGQAPQPQPTQPVASGSIHESRSYFLTIGETVIASDGKQVTINLVLQNPSNQPLTFRAADFTIQTNLGSFPIASNSPLMNTLTIPANASHAGTVLARTNTGEFQSIKLVWRPTSGGISKTITLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V0</accession>
    <name>A9B5V0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3105"/>
    <dbReference type="MEROPS" id="M14.007"/>
    <dbReference type="EnsemblBacteria" id="ABX05743">
        <property type="protein sequence ID" value="ABX05743"/>
        <property type="gene ID" value="Haur_3105"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3105"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019326_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03859">
        <property type="entry name" value="M14_CPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033810">
        <property type="entry name" value="Carboxypeptidase_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735303" evidence="2">
        <location>
            <begin position="28"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="3">
        <location>
            <begin position="457"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="632" mass="67841" checksum="CD2C6034EDC0F663" modified="2008-01-15" version="1">MKPSRIVRLVGSLALAAGLMAPLSALGQTRQPVQQTEPLDQARAYHLEGVTTREDRNAIAATGASIDAVHGKVLDITANAEEAAAIERLGFKLVELPELTDFPGADSAYHNYAEMTSNIAAVVASKPSIVSRFSIGRSYENRDLIAVKISDNVATDENEPEALFIGQHHAREHLTVEMTLYLLHLLVDNYGIDNRITNIVNSREIYIVFSLNPDGSEYDVATGSYRSWRKNRQPNSGSSYVGIDLNRNYSYKWGCCGGSSGSTSSDTYRGTAAFTAPETQAIRNFVASRVVGGKQQIKTSISFHTYSELVLWPYGYTYDAYPSDMVRDDYDAMAALGRTMASSNGYTPQQSSDLYVADGTYEDWAYGVHRIFAYTFEMYPRSSSPGFYPPDEVISRETTRNRESVLYLLEQTDCPYRVIGKEAQYCSGGGTPTPTATPGPTATPGPTATPNPVVTVFSDDFEANQGWTTNPNATDSATTGAWERGDPEATDSSGAKQLGTTVSGSNDLVTGRLAGSSAGAYDLDGGSSSVRSPAFTLPSSGNLSLSFSYYLAHGSNASSADYFRVSLVTSSGTVKVFEKLGSATDVDAAWTAATVSLNSYAGQSVRILIEASDASTASLVEAAVDNVSVTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X2</accession>
    <name>A9B5X2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3128"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05765">
        <property type="protein sequence ID" value="ABX05765"/>
        <property type="gene ID" value="Haur_3128"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3128"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054222_0_0_0"/>
    <dbReference type="OMA" id="EVAHEAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3160-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="250"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="437" mass="49223" checksum="8A2053B61D8E68F9" modified="2008-01-15" version="1">MNFLLIQPLDYLFVSGGAHKANRFLMEGLVERGHKCIVLYPLEENREKNGKEKLLKQLEQRQIQVVDASHPDLVHYHMNGVDVYASGGSLSFFTKLIHRITNEFHIDWTIVTEDRSFLWVEVAHEANPGRAIFLSHSQATLPFGPECFVDDPTKTRTLQQMADLICVSEYLQRYAKEWGNLDSTVLRFPSYGSGPFPFLANFDQGAVTMINPSMLKGSPIFIELAQRMPEVQFAAVPTWSTTGKDRAILEALPNVQFIQPSPDMNEVLKHVKVLLVPSLWGESFGQVVVDAMLRGIPVLASDVGGLPEAKLGVEYLLPVTQIREYSSISAKVYTAIPVVPAQDVTPWETTLRRLLNDREHYNDLAQRSQAAALNFINNIGIEHFERYFLNLQPRQTSVVPSLTPDPKVQRAAQLAALPAEQRALLAQRLKQRRGEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X6</accession>
    <name>A9B5X6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3132"/>
    <dbReference type="EnsemblBacteria" id="ABX05769">
        <property type="protein sequence ID" value="ABX05769"/>
        <property type="gene ID" value="Haur_3132"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3132"/>
    <dbReference type="eggNOG" id="COG1682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478006_0_0_0"/>
    <dbReference type="OMA" id="WLNPMAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3164-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="314"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="570" mass="63734" checksum="C56CA6B488A38EB3" modified="2008-01-15" version="1">MAQTINAARTINGQRRRLGGFHWFLLLLTIGMTLLISAPTLFFQTVQYDASATIQLDTQRYRSFMAEQTLQNQLCDASRNVVKSILPKFGSNTFGSACAALAADGSLILTAQATSPENAQAAADYTAQKLIQHIRAAGGRDSLRRLMEYELGLLLKNQPANDELGRRLRELIGVQAFDFSLHASTDLPTINAEDLNDLIRAFEVRFDQIAFELRQPDLPAERARDLKTARGLIGTILTDVLYSDPRYQSDDSQISAAYIKQAAILPTQARSQNFALKFGLALVVGIVGGILLVLADRAIGIVDKVRELWEYRELIRNLVLRDLRSRYKNSALGYVWSLLNPLLMISIFYLIFGLLLNSNIRHFHIFLMVALLPWNYFIGGMAEGMMSVISNANLVKKVYFPREILPITTLISNLVNFMLALPIMFLIMFITGAPIKATLLLMPVIIVIESMFILGMILFLSSVIVFYRDVSHIMGIVLQLWFFITPVFYPLDNIASANYAKLVRWLNPMASIVDFYRDIAYGGVTTIPDYPTPGLPSLDGVARTGLTALIVLCFGAYVFNHYSARFGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B628</accession>
    <name>A9B628_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3184"/>
    <dbReference type="EnsemblBacteria" id="ABX05821">
        <property type="protein sequence ID" value="ABX05821"/>
        <property type="gene ID" value="Haur_3184"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3184"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_969374_0_0_0"/>
    <dbReference type="OMA" id="ARRPPHY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3219-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="27973" checksum="54DD426A589D34B4" modified="2008-01-15" version="1">MLDLEQTEDVGTLLSAGREAAQRGDKTTARNALRKANRLAPNDVPVLIALAEVVGTFNERRLLLEQALQLEPDNIAAQGALAALKSGAANPHPAVNLPPIDPTPLMAPTSETLYCYRHPTVETGLRCIQCARPICSKCSERTPVGFICPECRKERRSPMYQVEPLDAVKAGAISLVLGGVGAYLLSPFGIFLFFLMGGVIGEMIMRAIDWATRKRGLIMQIAAAGSFAVGAILAAVFAVGFKIGLILFLGFGVFIIVARLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B698</accession>
    <name>A9B698_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3673"/>
    <dbReference type="EnsemblBacteria" id="ABX06309">
        <property type="protein sequence ID" value="ABX06309"/>
        <property type="gene ID" value="Haur_3673"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3673"/>
    <dbReference type="HOGENOM" id="CLU_1264732_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3712-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="30118" checksum="7E5CD96D1DD8A29B" modified="2008-01-15" version="1">MGQINLILVEGSNDKFILIELIKRRLNSIINNPSQADHDKALIIKHNDTRLRIEQSGSKEKAIHDLKFIFSGFNDSQQQTHDKISIIEELRVRLMQQDDENDDIVIGLILDADKDAQKTYAQVHTILAEKYPDVVPILPVEGLVLHAVDQPRIGVWIMPNNRDQGTIEDFFISLIRPDDALWQEVQHTISAVRKKADLTSLMFTEKDLRKAQIFTWLAWQKNPVVQMSKAIERNHAALNLNCEPVELFINWLTRLFDLPDSA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6J3</accession>
    <name>RPOB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="1">RNAP subunit beta</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoB</name>
        <name type="ordered locus">Haur_0244</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B6J3"/>
    <dbReference type="SMR" id="A9B6J3"/>
    <dbReference type="STRING" id="316274.Haur_0244"/>
    <dbReference type="EnsemblBacteria" id="ABX02896">
        <property type="protein sequence ID" value="ABX02896"/>
        <property type="gene ID" value="Haur_0244"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0244"/>
    <dbReference type="eggNOG" id="COG0085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_4_1_0"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000141702" description="DNA-directed RNA polymerase subunit beta">
        <location>
            <begin position="1"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <sequence length="1217" mass="135539" checksum="BD7775738547848D" modified="2008-01-15" version="1">MPQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQREGLRELFDEINPIDDFTGKNLELSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKTTGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSPGVYFKEEKEPTSGRSLHSAKLIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALFANVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRYDLGKVGRYKLNRNLWEKSRLFEGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDIDHLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEAATPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEGPNIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARAGARVDAELAKIIAIGVLNGQLLREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKIHPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVSCRHAEDFVQAPIASVDYMDVSPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQVVVARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEVIADSSSTQNGELALGQNILVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDILVGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISPGDKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAASRLGFRIATPVFDGARDEDIIKALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYILQEMLTVKSDDVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADDLISLDGINLSGMEKGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6N5</accession>
    <name>A9B6N5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1701"/>
    <dbReference type="EnsemblBacteria" id="ABX04344">
        <property type="protein sequence ID" value="ABX04344"/>
        <property type="gene ID" value="Haur_1701"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1701"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_0"/>
    <dbReference type="OMA" id="MACTMVY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1725-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="280" mass="31995" checksum="F995E81E1DAD5328" modified="2008-01-15" version="1">MFTVGEFARIAQVSKRFLRYYDELGLFPPASIDHANGRRYYSAEQLPALNRILVLKDLGFSLDQIRDLTHDQISADQMQTLLRQKKAEIEAHLHAEMQRIHRIESRLNALNDFDKPLNVVLKPMPGQPVLSTRIIAANFESGLQAMQHIRQHLPISKRYGLCFCICQDSNSSIYDMDLEIGCFIEQTTHRPVRISPQLELQFNHHPASKLMATSVVQGPLERILTSYEQLGRWAELNGYRPIGMPREISLQLPQTADASDLLTEVQFPIEPNENMMSSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B771</accession>
    <name>A9B771_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4">4.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Beta-thionase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Serine sulfhydrase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_3718</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homocysteine + L-serine = H2O + L,L-cystathionine</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3718"/>
    <dbReference type="EnsemblBacteria" id="ABX06354">
        <property type="protein sequence ID" value="ABX06354"/>
        <property type="gene ID" value="Haur_3718"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3718"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_0_0_0"/>
    <dbReference type="OMA" id="RTPVFKF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3760-MON"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004122">
        <property type="term" value="F:cystathionine beta-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005857">
        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="345"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX06354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="463" mass="50315" checksum="685560AC6E54BA41" modified="2008-01-15" version="1">MTETATMAMPQIHDTILDAIGNTPLVRLNRVNRGVRAQVLAKVEYMNPGGSVKDRIGIAMIEDAERSGRLKPGGTIVEPTSGNTGAGLAIAAAIRGYKTIFVMPDKMSDEKIRYLRALGAKVVITPTAVEPDDPRSYYSVSKRLAEETPNAILAGQYWNQANPEAHYRTTGPEIWRQTAGKIDAFIAGMGTGGTISGTAKFLKEQNPNIQVVGIDPVGSLYTEYFRTGQLGPAFGYKVEGVGEDFLPTTMHFQYVDDVVQVGDKESFVMTRRMVREEGLFVGGSCGMAVAGAMRWLRAQNWDESKTAVILLPDSGVRYISKIFSDDWMRENGFLESEPISQLLDIRPRSVISAKATHTVAQVIQDMKANDISQMPVVRDDGTLVGLITEVDLLDYLLSGAGQMDHQISDIVSSAVATVGPDTSIDALTEVFSRGQVGVVVDESDVVRGIITKIDMIDYLANKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B780</accession>
    <name>A9B780_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06363">
        <property type="protein sequence ID" value="ABX06363"/>
        <property type="gene ID" value="Haur_3727"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3727"/>
    <dbReference type="HOGENOM" id="CLU_1560837_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3769-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="19416" checksum="BFC90CDB394FC1AB" modified="2008-01-15" version="1">MAHSDVYDPIHNELWALSVMASTLDNVRVRVSGLQPDVQQERPQGFERSLAHVIASLRRGEAELIEVFEKALKAENPSLNTIFNRYPKAFVLNPAEELGSFMDSRETSLGLLRSLTSEQWERKVNDPERGLVSLSQLAVERANLDLEEMDYMAQLRQAILRLEPIQGNDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E7</accession>
    <name>A9B7E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02920">
        <property type="protein sequence ID" value="ABX02920"/>
        <property type="gene ID" value="Haur_0268"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0268"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798707_0_0_0"/>
    <dbReference type="OMA" id="HRANILY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-271-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735342" evidence="1">
        <location>
            <begin position="25"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="220"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="347" mass="38439" checksum="9D771327AFCEACB3" modified="2008-01-15" version="1">MRLRFLLMMILVIGSLSFSPKPAAAQTSLCFADVPGISNCISGRFLSYWQQNGGLAVFGYPLSPAQSETTANGTFTTQYFERQRFELHPELAAPYDVLLGRLGAEIYERNHGNWRNAPKTNPSTQGCLVFNETGRSVCEPFLSYWLNHGLLDGSLNAYEQSLSLLGLPLTEPLLEQNPDGDWVMTQWFERARLEDHGAKGVLLGRLGAELKAQPTPSYPSEITALVDAINRQRNQAGLSSLTINPTLNQAAQIHSDDMARNNFFEHTGSDGSNAGQRMQRVGYSWRAWAENLAAGYTDAQAIIDAWMQSPGHRANILYADVSEIGVGIARNPNSEYQIYWTVNFGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7L1</accession>
    <name>A9B7L1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0332"/>
    <dbReference type="EnsemblBacteria" id="ABX02984">
        <property type="protein sequence ID" value="ABX02984"/>
        <property type="gene ID" value="Haur_0332"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0332"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_529738_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-335-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045232">
        <property type="entry name" value="FAM234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419">
        <property type="entry name" value="PTHR21419"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732591" evidence="5">
        <location>
            <begin position="22"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="580" mass="63174" checksum="741C7B2E7F9C3383" modified="2008-01-15" version="1">MVLRRMMFVLLVIFSLSTVSATSLETPSAEPLDAASPASPAATNAYTMRAGFPATKPNGSYFSSPTVVDLFKDGSPEILSADATGCIWGYNIYGQLLPGFPWMTGGACANTPRINGSLVVADINEDGLLEIVVGTRGKGTSVGQRGKVIVYQRNGAILSGWPKEMEWAYITNGNFPEVVHVAVDDIIGDSKLEVIATTTNEAGSNTDYAPNVHAWYYTGNVVTGYPKSSDKGSGIWGHPALADLDNNGKSEIFVGRDELYFYRYKNDGTQYAGWPIQTYTHVNQTTWNVHDYIEFTRSGPAIADLDNDGSYEVIAAGKVRTPDGDPHNNYDPQSASAVFVTEPDGTRRPGWTDAKRAGAPLDVNFTPNNPIVVADLDGNGEKEFVVTFDDGTIRAYRENGTQIWSYFYAEEPVQGAPTRKVFGSEVVIADVTGDRKLDIVFGTYSFDRLYAGIVGLYALDARNGALHSGFPLSLPNEGTASDNSAGSQKGIQAAPTISDIDNNCYVEILAHSRAGNIYVWETLGRNLPELMPWPMSRQNLQRTAWVQNPPEPRQHVFAPEQIQGGDFNVYLPMTRMGCDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U4</accession>
    <name>A9B7U4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1829"/>
    <dbReference type="EnsemblBacteria" id="ABX04472">
        <property type="protein sequence ID" value="ABX04472"/>
        <property type="gene ID" value="Haur_1829"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1829"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055286_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1857-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="352" mass="40426" checksum="43EAF81F85971CED" modified="2008-01-15" version="1">MILIITKLLTDTTVVSVRELLEAQGQEVVVLSQEVMEQNASFRINQSADGHAQAILRLGEREINFATDVSAAWIWRSWRPEPLLERYQQLAKQTDEWNFFSSEWGALYKGIVLALKCHNIFCVNPPPFHEAFEEKCGQLWTAADIGFKIPDTLFTAHLPYAQDFYEQHADSIIYKPFRPFFKMIPPKDQEPSKIAKLLTNRVSKQHFSNARNAVPTPGIFQPYVEKAFELRIVVVGREIFSCAIHSQSSERAREDWRRYDIPNTPHQIYALPDDLAAKVRTYMDRLQLVFGSIDMIVTPEGEHIFLEINPNGQFDWIDRLTGMPIYEHFAAMLQAASIDYPIPLAQEAVNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7W4</accession>
    <name>A9B7W4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular HAF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04492">
        <property type="protein sequence ID" value="ABX04492"/>
        <property type="gene ID" value="Haur_1849"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1849"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_794036_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1878-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014262">
        <property type="entry name" value="Extracellular_HAF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02913">
        <property type="entry name" value="HAF_rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="37622" checksum="2CD1E9F3023D33A2" modified="2008-01-15" version="1">MLGSSKRIGCGLIVIGLLGLTQSQSRLMHAQTPTPPNPGYTSRTVGTMGGHDAYARDINDFGRIAGGSETELSDTRAFVWRRGTFTEIPPLGGGDKSYGHGINDSGFVVGESNTYTHEQRAFYWTGGDPIDLGTLGGPSSIAFDVSNGERIVGRSSTSTGETHAFMWYRNTITDLGTLGGTYSTAREINDHKVIVGSSTNASGVNRACIWKNGQIIDLNIPAVQSYGVAINNSEQVVGTMVMTNGISRAFIWDDGITTILSTTTPYSTFANDINNLGVIVGTTYDTDGYSKATVWRNGTVLYMWPEDTGLTEHQTSAASINDANQITGSDRISDWDYFSTDIMLWQLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B816</accession>
    <name>A9B816_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3313"/>
    <dbReference type="EnsemblBacteria" id="ABX05949">
        <property type="protein sequence ID" value="ABX05949"/>
        <property type="gene ID" value="Haur_3313"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3313"/>
    <dbReference type="HOGENOM" id="CLU_758142_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3350-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="40238" checksum="CCB4E6FE9088BEFC" modified="2008-01-15" version="1">MKRFYIVLVLISLLSGCDIDQPQPTVVVIPTLDLRPTPTLLALATVRPTPSINQPTTVPLATPSVGTNTVISASDQLLVDKNDVVRTQFGPLSPSQQWLITQSITQEQFELHAPGLSFIALSRSYQGQALGWSSDGALLLWRSQAQPDLLQAIEPFSGQSATVLTSTNGLIQAALMTNSALYYAAGDDDLRIMQVGGNTQEQVIIRLPKRQLLAGGLQLSPNRDQLALLLQVRDQTALELQLFDLPSNQIRLLDQSQRGTNTPRLVWNARGALAYYLGDDFRIYEPSLNTIQATNLGVEPLAWLDDGIIVRSLDRNALVYWSPTQVYPINDSAGEPRYANDLQALDQTQFLLLNQGAIWQIQLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B839</accession>
    <name>A9B839_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3336"/>
    <dbReference type="EnsemblBacteria" id="ABX05972">
        <property type="protein sequence ID" value="ABX05972"/>
        <property type="gene ID" value="Haur_3336"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3336"/>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796066_0_0_0"/>
    <dbReference type="OMA" id="HIIVCGC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3373-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="130"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="267"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="39565" checksum="2719DA6D5EE3C87F" modified="2008-01-15" version="1">MKPAKTPSRKARWRRLIAASLRDGWIVFRDSGIWLGLWLLLWLGFTLAIWAGTRPVLAFNQALYQAFSQMTLNPVPLPEPWWLQVLFYLAPALNIILLARGALNMGILLFDKRNRREAWQMALASTYRDHIIVCGLGKIGYRVVGQLLASGCDVVVIDAHNDGPFHELVMGQHVPVIIGDARQPELLHEAGLRHATSLTVVTGDDLTNLDIALTARELHPDIHIVMRVFNDSLASKLSSAFHIQTAFSTSALAAPTLAAAALGRGITNALYVAGKLLSTVEITVARDGIFDGRLIQTVENQHDISVLYRRGRNGEDLRPRGDERLSSGDQLVIIGPLAAINQIQTLNKPNAAPHAPYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B896</accession>
    <name>A9B896_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase T-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3813"/>
    <dbReference type="EnsemblBacteria" id="ABX06449">
        <property type="protein sequence ID" value="ABX06449"/>
        <property type="gene ID" value="Haur_3813"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3813"/>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_6_0_0"/>
    <dbReference type="OMA" id="WTIDCCE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3855-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010162">
        <property type="entry name" value="PepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF2">
        <property type="entry name" value="PTHR42994:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01883">
        <property type="entry name" value="PepT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="5">
        <location>
            <begin position="171"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="360" mass="37809" checksum="2921A6C9E4D6C052" modified="2008-01-15" version="1">MAINQERLLDTFCTLVRIDNPSGEEAAMAAHLIERCQALGLECEQDAIGNVIARLAGVGSPLLLNAHMDSVAPCHGKQPVIRDGNIYSAGDTVLGADDLAGVTAFLEGIQAVLESGQPHRAIELVFTVQEETGLYGARALDYSKLQAKQGLAFDLNGDVGAICIGSPAHDSFTATITGVSAHAGVAPEKGISAIEVAAHAIAAMPLGRLDDETTANIGSIHGGKANNIVPDSVVVKGEARSRNQAKLDAQWHIMRNAFEQAAAKFGATVEIEHKQHYGPSVLAPDAEIVQLLNQAIRAIGLEPSLVVTGGGSDVSIISNNGIETANLAIGYENIHSVDEFIPIVQLQRAAQIVEQMLLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8C4</accession>
    <name>A9B8C4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3841"/>
    <dbReference type="EnsemblBacteria" id="ABX06477">
        <property type="protein sequence ID" value="ABX06477"/>
        <property type="gene ID" value="Haur_3841"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3841"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_278586_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3884-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735531" description="DUF11 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="766"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1140" mass="118729" checksum="8BC2E2B56EF38270" modified="2008-01-15" version="1">MRRMLQFLAIVMLVIGGTWPQFQANAAQSEPNLQAPTALNAVADDQFWNNDNLVADANNKINAITTLNNDLFVGGLFSRVGGIDAARVARWNGERWFALGSGISGANAKIEAIDASTSGNVYAVGEFASAGGVAADSIARWNIATQQWSALATNVNGSVDAVVVVPDANGDIVYVGGSFTSIDGVSANRIARWTNGTWSALADGLAGTNAQVFAVAFNPSNTAQILAGGVFTSANGLVANNIALWDGNAWQSLGTGTNNGVNGRVRFVDFRSSNFVVVGGSFTSAGVVLPVGGSAAWRGGNTWEAFTGRGFNPIASNSEIRAIAELPGRIFVGGNYFGLVNSSGQVTTGNLMGLWNGTTWQFIPNSPFKISQIERIGTTEQFFVTGESTNILNPSGFVSLFIPTPTGSNQPHQFLPLGGTISGPDNAVFAVHASASGVFVGGEFNRASDQAINNIALFNPTTRTWSPLFGKTENGTNDTVRAIAPFGSDQLIVAGDFSEAGGINTAGVAKWDIGDQQWFEISNSINGSVRAIAINGSEIVIGGDFTQIDGTTVNHIARSTNGGNSWSALGSGIGGPVHALVFRSGTLFAGGDFSTASGVSANNIARWNGTAWQALRGGTDDIVFSLAAFGTQIAVGGSFNLADGVAGTSAIALVHPTTGVWSPLAQGFGIGNTVQTLAVRGTDLYAAGTFFYSQPNPTRPTNIARWDGTAWQALGSGISGGTGNADSVKGFAMSVRGDDLFVGGIFDAAGSKSSKRFAQWTQPEVDLAVSLRDSADPVQVNTPFQYNVSLINQGIITATSVIYEQTFDSSVSFGNISASQGTCSFSNATTLRCTLGTLTPNARATVVVNATPTQVRTITSRGTLSSPADEPITANNQQQISTQIIAPGNPVPTISSITPNSFVQQAIGLPVQISVSGTGFVASSKVFVDGIERPTTFLNNVQINFSMPVNTALGNHSVIVRNPTPGGGDSNSVNLAVLRNNVGFSSITPDTGGVDVGLQTTFTISWTHTTDPWRIIDSLDLRLVNADGIGLWARFTEGVSGTFSLLNSEGDIIGTAIAETPNILSSDTAELDVEASSFAGSGPTGFSMNVTFNVTFNEAARGRYNIELYASDDHGELQGPDVLGTFDVGIHQIFLPMTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J8</accession>
    <name>A9B8J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07662">
        <property type="protein sequence ID" value="ABX07662"/>
        <property type="gene ID" value="Haur_5032"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5032"/>
    <dbReference type="HOGENOM" id="CLU_028885_2_0_0"/>
    <dbReference type="OMA" id="HDFRERI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5095-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="53"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="407"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="511" mass="57772" checksum="B19EFC0D7954B78A" modified="2008-01-15" version="1">MTLYPQSILPVPASTAHALHAAFPNGNRYIDLRAEFGTLFTDDHFCALYPATGRPVVVAPWRLALVCVLQFMEGLTDRQAADAVRRCMDWKYVLSLDLTDPGFDFTVLHDFRERIIAADATHDLLTRFLTACQARGLIKTRGTHRTDATHMFASVRTLHQIECVLETMHWVLNTMPDHDPAWVEAHVPPAWFERYGLRADRMRFPKDTSKRTALATTIGQDGATLLDWLAQPATPHVLRDLHCIAVMRMIWMQQFYRCTIPGAEQLRLRTMDEKPATAHLIQSPYDVEARYSSKRDTVWNGYKVHLTESCDDGYPDLIVHVATTSATTQDFRMGASIQDAVAAHGLTPAIHLMDGGYVDSHLLVHAQQYDTMVIGPTFGSYSRQRREDHGFALAAFAIHWEAQTVQCPQGQMSVKWTPGQTTHHGKAACRACSVRAHCTAAKDEPRQRTLRPQQQHHALYDARAREQTAVFKHQLRAGVESTMAQGALRFGIRRSRWDGLGQCIWVHAVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L0</accession>
    <name>A9B8L0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07674">
        <property type="protein sequence ID" value="ABX07674"/>
        <property type="gene ID" value="Haur_5044"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5044"/>
    <dbReference type="HOGENOM" id="CLU_030671_3_0_0"/>
    <dbReference type="OMA" id="TEFQIGK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5107-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="24304" checksum="6520697674658DB6" modified="2008-01-15" version="1">MAQFIDLSHIVEAGMITYKGIPAPIICDFLSREASRNNYAEGTEFHIGKIELVANTGTYLDSPFHRFADGKDLSELTLTQIAELEAVLIRHDLANGRAIEAEVFAGVDLKGKAVLVNTNWSQHWRTDQYFEGHPYLTAAAAEYLVQAHATLVGIDSYNIDNTDTNTRPVHTILLGNNIPIVEHLCQLDQLPTSGFHFSAVPVKVKHFGTFPVRAYARID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L2</accession>
    <name>A9B8L2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_C25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07676">
        <property type="protein sequence ID" value="ABX07676"/>
        <property type="gene ID" value="Haur_5046"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5046"/>
    <dbReference type="HOGENOM" id="CLU_830768_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5109-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C25" evidence="1">
        <location>
            <begin position="4"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="34782" checksum="AE2E124DD8337B39" modified="2008-01-15" version="1">MLVLALVGDGSADPRDVLGYGQPPLIPPFLAEVDLWLGDTACEACYGQLDGADPLADLLPDLPVGRWPAKTVEDVTALIAKQHRYATAPWGAWQSTVGSVADNAEGALDFPQLAAQSEAVYPITMTLHRAYYDPQATSADPAWYEAHARAVRERVLAIWQAGAVLMQYTGHSHAYQWAVTDPRIEPRGLLDLNAVGDLRNGERLPLLLALTCLTSAFHQPSPRGTTLDEALVLHPDGGALATWGSSGLGVAHGHDHLQHGLVTAAMTLPRPTLGQMTEAGVLELAITGQCCIDALRTMLLLGNPATVLRVSPTPQRVWLPLVGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8M7</accession>
    <name>A9B8M7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07691">
        <property type="protein sequence ID" value="ABX07691"/>
        <property type="gene ID" value="Haur_5063"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5063"/>
    <dbReference type="HOGENOM" id="CLU_2301988_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5125-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="10661" checksum="EDFAA6949639CA0A" modified="2008-01-15" version="1">MSAALDSVVVLWTVGWAVVTVLALLLRRWLVTRLATGVVTLPPPPLGSWLPTQDAVTTALGPWLAQVGVPPLPLGVWLAVDWSRAIPAQIPVTQGVHDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B919</accession>
    <name>A9B919_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07833">
        <property type="protein sequence ID" value="ABX07833"/>
        <property type="gene ID" value="Haur_5206"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5206"/>
    <dbReference type="HOGENOM" id="CLU_036902_5_0_0"/>
    <dbReference type="OMA" id="KGHINRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5268-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="11"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="37881" checksum="D91689ED3F61BC25" modified="2008-01-15" version="1">MNRSPVYHCFVGIDIAAKTFVAAYAEPGHAASSPRTFDQTEAGFAAFQAYLPATILPTQILIAMEATGSYWIRLAVTLHQAGYAVAVINPKHIHNFAKSLPRRAKTDALDADVLLRFATERQPSCWTPPPTVYHELRQRLLARDALLAMRTQARNQQHALSQWPVVVAEVTAHFNTVLAALDTQLAMLEREITTTMQLGDWAASATLLLSIPGIGLHATAWLLVSTLNFTLCATPEAAVAYAGLNPLARESGTSIRGRPRVGRGGNARLRTVLYMATLSASRYNPPIQALYTRLRERGKAVKVARCAAARKLIHLAWAIVKTGQPFDPGYQQKLREHRVMVAITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B931</accession>
    <name>A9B931_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_5218</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="6 7">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6 7">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07845">
        <property type="protein sequence ID" value="ABX07845"/>
        <property type="gene ID" value="Haur_5218"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5218"/>
    <dbReference type="HOGENOM" id="CLU_058798_0_0_0"/>
    <dbReference type="OMA" id="TKVTVEH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5280-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0614">Plasmid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="114"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="36662" checksum="A111FFA103CDEDD1" modified="2008-01-15" version="1">MPQPESEPIESLIDRWWTNPGDDLTAATRTRYRSALRRLCRWFAAAERRSLLLADLHPISLAGYREALKQTDAASTVNTHLSAIRTWCVWLVDQGYLATNPAQRLKLVKRTTPSAPKALSPAHVNALLRQAQFTRYPLRNTAILQVLIQTGMRISECAALCWHDIQYGERSGHALIRAGKGNTVRTVPLNESARCALASYVAPLLGVQPSLHKVARAWPQRQEGDPRCPLWTSERQHALSLREMSHMIHQLVRDTSARKLLPASTTPHSLRHTFATRYLARHPHDLVGLARLLGHRSITTTQIYIQPTAEQLAARVDQIDLNAYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU96</accession>
    <name>A9AU96_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0364"/>
    <dbReference type="EnsemblBacteria" id="ABX03015">
        <property type="protein sequence ID" value="ABX03015"/>
        <property type="gene ID" value="Haur_0364"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0364"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_0_1_0"/>
    <dbReference type="OMA" id="LWPASIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-367-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="282" mass="31127" checksum="E7CEE91912CF0CE2" modified="2008-01-15" version="1">MARVKIITDSTADIPPALAQELNITVIPIYVHFGDQTLRAGIDISNEQFYRRMAEGGPYPYTTAPAPGVFEQYYRQFSREYDGVFSIHLSNRFGGVVKSATIARDKLPASLTRVEVIDSTSTSLGLGMVAIAAARAALDGASIDEVHRVVMQTIQLTHVVFFVDSIDYLERSGRLSQASAMLGSMQRIKPLLILDDGEIVPYDRTRTRAKAIEGLFTFIEDFPKVEQVAIMHSTTPDDVEKLLEKIDPIYPRDQVMIVEYGPALGAHLGPNAMGVVVYEGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE9</accession>
    <name>A9AUE9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0417"/>
    <dbReference type="EnsemblBacteria" id="ABX03068">
        <property type="protein sequence ID" value="ABX03068"/>
        <property type="gene ID" value="Haur_0417"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0417"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_2_1_0"/>
    <dbReference type="OMA" id="MMAAIME"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-423-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="16046" checksum="900870DFCAEB1343" modified="2008-01-15" version="1">MEWQKGDYTISTDSARLDHTAIIAALHETYWAAQRQPTTIVRSLTHSFCFGVYYNQQQIGLARVVTDYAVFAYLADVYILAEHRGHGLGKWLVQTVLAHPDLQGLRRWLLATRNAHGLYAQVGFIPIVSAEPWMEIFNNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV3</accession>
    <name>A9AUV3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3907"/>
    <dbReference type="EnsemblBacteria" id="ABX06541">
        <property type="protein sequence ID" value="ABX06541"/>
        <property type="gene ID" value="Haur_3907"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3907"/>
    <dbReference type="eggNOG" id="ENOG5033Q6F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_965666_0_0_0"/>
    <dbReference type="OMA" id="EAGYYQS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3949-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="31871" checksum="3E47B38C07D58A64" modified="2008-01-15" version="1">MSSRYLEMVRGQRRNRGGGFQFTAKTLLVVLAVCAMVGSAVYWWGIQSVLTPNKMIAGSFTLILVLAPPSLVSFLIPWSPAGMLLQKINARTLGYVVVVVCALILVYYSFTLQYQWWGTQAVVQDSNIVLLQVLVGLIGFIFIPALLWTPVSSEELVEQIRQAHLVRRYELQTQADIAILRNTLLRAQEKALIGFANLTVQEKEELASVMRGLVRGIDTTMKELAQSVKAVSGTVTPFAALEDNEDIKGYLDYVADSLMDTSMNPGTKPTNTTSMDRSPMDRPGGYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL6</accession>
    <name>A9AVL6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3984"/>
    <dbReference type="EnsemblBacteria" id="ABX06616">
        <property type="protein sequence ID" value="ABX06616"/>
        <property type="gene ID" value="Haur_3984"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3984"/>
    <dbReference type="eggNOG" id="ENOG503470Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1270412_0_0_0"/>
    <dbReference type="OMA" id="PPAPRYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4026-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="196" mass="21021" checksum="C412F147D6CD8DBD" modified="2008-01-15" version="1">MANRNRKSTDSTKTTAVERVDIDRSYKFMIMTSFILNVVLIIGLVVLAIALFGYKTGLAPLKPTIAKLTDTIDGLSNATIKASVPLNEQLPITLQVPVSQNTNVRITQAVPLQVPADITLPGVGYLKASVALNLPEGLELPVYLSLTIPLQASVPVSLTVPVNIPLKDTELGPQFRSLGELVQPLADLVNGEPTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS2</accession>
    <name>A9AVS2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell cycle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4040"/>
    <dbReference type="EnsemblBacteria" id="ABX06672">
        <property type="protein sequence ID" value="ABX06672"/>
        <property type="gene ID" value="Haur_4040"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4040"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_2_2_0"/>
    <dbReference type="OMA" id="TGMAMPF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4083-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="380" mass="41673" checksum="D553F7D997F9A738" modified="2008-01-15" version="1">MSTSIRARSWREFNPIMVVAVLLLLAISVPMVYTTTVGAAGTLVFGLGSSFAKHIVWVSMGISLMFGLAMVDYQLLRSLAIVLYIAALGLLGMVVALGQVKYGAQSWIGSSQLSFQPTEPAKLMVIIALAAFWSKHGDEPSPWKSVFISLGILAVPLGLVMLQPDFGSGMVMIGIWLVMSLVANTRWVQYGILTLFSAPVVVLAWLKFDEYQRERLTVFLTPERCETDLEFRMRACWQIIQSRLAIGNGGLGGMGLLRGVQSQLNYLPVQESDFIFAVTAEELGFIGAAVVIVLQLIIIWQIWRVVERARDPFGRLMAAGVAGLLLVHCLENMGMNLIMMPMTGIPLPFLSYGGSFTLTVLMGIGVVLSVSIRSKRWSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT9</accession>
    <name>A9AVT9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphodiesterase/alkaline phosphatase D-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4057"/>
    <dbReference type="EnsemblBacteria" id="ABX06689">
        <property type="protein sequence ID" value="ABX06689"/>
        <property type="gene ID" value="Haur_4057"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4057"/>
    <dbReference type="eggNOG" id="COG3540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022808_0_0_0"/>
    <dbReference type="OMA" id="DHEVRNN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4100-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732180" evidence="1">
        <location>
            <begin position="25"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD_N" evidence="3">
        <location>
            <begin position="38"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="2">
        <location>
            <begin position="139"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="585" mass="63113" checksum="6DC2BBA9774793AF" modified="2008-01-15" version="1">MRRLFGLCCLCCLLAGSWSGSSSVGRTNLLFPPADLPQGVAVGDVTATSAVLWARSASLGSVSFEYSLNANFNPVAGSATVSITDTMQPAKTSISNLQPATSYFYRATTLSNTSFAGRFRTAPTSGTYSNLRFGASGDQQGALAPFPALANADQRDLDLFIHLGDSIYADIGSPVLGTTAKTLAEFRLKQTESYSTRLNLNTLADLRATTAWLATTDDHEVANDHAGGAAPSSDPRFLPTNASYINDTDYFEAGYQAFVEYNPVNALFYGATGDLRTANERKLYRYQPYGNTAAFFVLDGRSFRDQKLPAPNNTPSEIVAFLTAVFSPTRTLLGQAQLSQLENDLLAADQANITWKFVIVPEPIQNLGTAAANDRFEGYAAERSRILSFINDHAIENVVFIAADIHGTVVNNLSYQTAAGQPQIPTNAWEISVGSVATTSPFGMRVAAGALSTGIISSTTYNNYLQLPNDQQDAAAEGWLNTVLNVFGYTPVGLQDAPFAERTTLLQGRYFAGHYFGWTEFEISQPDQTLRVSTYGIDTYGTSELANNPGEVVSRMPVIVQQFEVDPIVSISPTLILNYLPAVTK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-04-25" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD5</accession>
    <name>KVDS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">(+)-kolavenyl diphosphate synthase</fullName>
            <ecNumber evidence="2">5.5.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Class II cyclase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Diterpene cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2015" name="ChemBioChem" volume="16" first="772" last="781">
            <title>Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus.</title>
            <authorList>
                <person name="Nakano C."/>
                <person name="Oshima M."/>
                <person name="Kurashima N."/>
                <person name="Hoshino T."/>
            </authorList>
            <dbReference type="PubMed" id="25694050"/>
            <dbReference type="DOI" id="10.1002/cbic.201402652"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>COFACTOR</scope>
        <scope>DOMAIN</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of (+)-O-methylkolavelool. Catalyzes the conversion of geranylgeranyl diphosphate into (+)-kolavenyl diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2E,6E,10E)-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54676"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="ChEBI" id="CHEBI:138311"/>
            <dbReference type="EC" id="5.5.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="5">The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity, presumably through binding to Mg(2+).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.29" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AWD5"/>
    <dbReference type="SMR" id="A9AWD5"/>
    <dbReference type="STRING" id="316274.Haur_2145"/>
    <dbReference type="EnsemblBacteria" id="ABX04785">
        <property type="protein sequence ID" value="ABX04785"/>
        <property type="gene ID" value="Haur_2145"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2145"/>
    <dbReference type="eggNOG" id="COG1657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041269_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2173-MON"/>
    <dbReference type="BRENDA" id="5.5.1.29">
        <property type="organism ID" value="2656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106242">
        <property type="term" value="F:kolavenyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="PFTB_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000443953" description="(+)-kolavenyl diphosphate synthase">
        <location>
            <begin position="1"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DXDD motif" evidence="5">
        <location>
            <begin position="311"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="C7BKP9"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="25694050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="25694050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <evidence type="ECO:0000305" key="5">
        <source>
            <dbReference type="PubMed" id="25694050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="521" mass="58496" checksum="DE1EBE4662E3E4AF" modified="2008-01-15" version="1">MSLIVDILIDDLRALIRDLGQNGGLMSPSVYDTSQALRLYPTPSEEHVWPAVNWLISQQQSDGGWGNPSMPLSRAVPTLAAILALRRHCQRRSTFDGLLEAKRFLRRQLEYWEKPLPDNLPVGMELLLPYMLEEAYREEHQDDIDDVPIKLRLNIPLAPYRELIALGEHKRSLIQQKKPRAGTAPVYSWEAWASHADPELIDGSGGIGHSPAATAAWLFAANHNPNLRNEIAGAENYLRQASLATSESAPCIMPTAWPIPRFEQSFSLYALVTGGILDFPSIQDVLKPQIADLHQALKPRGIGFSDDFMPDGDDTAAAVAVLIAAGYPVDLAILNQFEREPYFVAYHGELQPSISLTARAVHALDLAGVDISRWWKIFIDAQKLDGSWSGDKWNTSWLYTTCHVLIALKNSPYKTAMKEAVAALQVHQHPDGGWGIINRSTTVETAYAVLALQNLREAGLLDDDDIHMLQRGYNWLCIHYRPFRMKEYQCWLNKEIYCPQRIDRAYELSAMLAVTLGELKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE5</accession>
    <name>A9AWE5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04795">
        <property type="protein sequence ID" value="ABX04795"/>
        <property type="gene ID" value="Haur_2155"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2155"/>
    <dbReference type="HOGENOM" id="CLU_806024_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2183-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="37477" checksum="A5EB223C91E0B3E4" modified="2008-01-15" version="1">MWIIIGFCAQCLWWEQPQQVKPTSVAQIEPTAVPEAANSAPATGNQANDLIDQLTDPQKTAEKLKTLQSYRLRSITKISTKNAESSNESISETLEERINQPLAVHLEVKTNTPDPTNSTWLIDGSVYQVQDTGTEQICNATVLDPQMMEQTFDMARSFNGGMLNVLAASFEPQLIAESESVNGMTAAHYHVESDTAGMLIKGDFWITPEGILIKSTSSMDISSEGNSMITETSIELDQINQIAPFAVPASCTQVADTMMGSLPTVDDVQNLLMDESLMSYSTSMPMSDVIDFYKTELANQGYTVSSIYENAEGTMLQAVNSSHTFNLTIGTAMNGLTGVLVQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV4</accession>
    <name>A9AWV4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0707"/>
    <dbReference type="EnsemblBacteria" id="ABX03355">
        <property type="protein sequence ID" value="ABX03355"/>
        <property type="gene ID" value="Haur_0707"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0707"/>
    <dbReference type="HOGENOM" id="CLU_1213479_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-719-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="24521" checksum="58FFAFD558760B2B" modified="2008-01-15" version="1">MICSACQANIRDTAQHCTACGAKINQPSAATGPLPQAKLAKPRRRWVKSWWSFILGVLSTGLILPLIGIIALWIFGGTNEARTPSPVPDERPDISVDIDHSYIEQAIATNPDFQNPQVILGNHPKGGVAMTVTLGYPLPLVGVQDIQARTQIAAIDGKLVVTTEHVGLGENGRLSIPGSIIENMLSSTLNQEIDKRLRSNPQLEIAIINTSTSNQVLRVAAIITTKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV8</accession>
    <name>A9AWV8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0711"/>
    <dbReference type="EnsemblBacteria" id="ABX03359">
        <property type="protein sequence ID" value="ABX03359"/>
        <property type="gene ID" value="Haur_0711"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0711"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_0_0"/>
    <dbReference type="OMA" id="YRAHQAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-723-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="247"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37281" checksum="21E401DD6668B046" modified="2008-01-15" version="1">MADAAALLAQAQTQLANALQALRGEAAQLRERHTAIAQQGRQMYRTADELAVQRTFAEQLGTPAVGRLRQQEAELRSKMANLDAETSATAEALKRLEQLIRQIEMSSTSLSGTTTIGQQNDPWALALRGQIIQGREDERLRLAREVHDGPAQVLANVLMGLEHAMNLHQSNSPQIEPFLHELRSAARQGLHEVRGFIADLRPGALDQGFPTALADYVQKYQQTTKVKVTIDLLHWPNRLPAEAEIVLYRVTQEALQNIHKHARNANVLIRSMLQGNLLIVTIRDDGPGFDPREVVRRSGKESWGLTSMRERVALLGGDFAIASRPGAGTEVTIRITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV9</accession>
    <name>A9AWV9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0712"/>
    <dbReference type="EnsemblBacteria" id="ABX03360">
        <property type="protein sequence ID" value="ABX03360"/>
        <property type="gene ID" value="Haur_0712"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0712"/>
    <dbReference type="eggNOG" id="COG2764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_17_2_0"/>
    <dbReference type="OMA" id="MTVKLTP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-724-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="16404" checksum="4801E4A9A1B86999" modified="2008-01-15" version="1">MTIAVTPHLNFHGNARQALEFYQAVFEGELVLTTYADVGAPKDTPIADTIMWGQVTTASGFRLMAYDVPTTEQLPALQTVTSRAHGLTLTQASFFISLRGQQVNEVMELWAKLAEQATIIEPITQTPWSQLFGMLTDRFGITWVVDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX15</accession>
    <name>A9AX15_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2183"/>
    <dbReference type="EnsemblBacteria" id="ABX04823">
        <property type="protein sequence ID" value="ABX04823"/>
        <property type="gene ID" value="Haur_2183"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2183"/>
    <dbReference type="eggNOG" id="COG5617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294533_0_0_0"/>
    <dbReference type="OMA" id="GNYHSAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2211-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1081" mass="122328" checksum="C53033F05A16E20C" modified="2008-01-15" version="1">MRYHFMQRRVPINPHLLTALILVIAFHGILLVSGNFKRTYDAYVHIFFADHYRRTWFDHWDYRWYTGFPLISYPPGSQQSIGLLGMVIGLLPAFVVVQLAALLNLTLGMYRFAKLWVSEEAAGYAALLIVFSSSICETVHVFGQLPTTFSLGFLLNTLPFVKRWLSEGDWRDLIRAWLLHAATTAGHHVTTLFGAVFFAGPVILLALVEAFRQAKADEDTLHPARITRSNIRPLIVRRLRRIAPPLIRTAIYGPGLIAALVLVVLPYWLWSSSDPISQVPIPHASRDSFIENPNAGIVFWLLPYGSTLLVLPYLFYKGFFSRAWPMALSISALFLLGTGGTTPIPKALLGGAFDILTLDRFTFWATILFTPLLGEFVVSMRHGNLARYLRDQFGNKMWRITQVCCVLIYVGVAVFTSNFTQFRRFQPDAIDPVPLVAFIEKDEHWRWRYLMLGFGDQMAWVSAQTTATTVDGNYHSARRLPELTTTPVERLEGAKFRGIPGIGSLQQFLAVPDKYNLKYVFSNDQFYDPLLYFSGWHRIQRLENGLVVWEREDIPPLPEILPRREIPWFQRIIWGVVPPTALGLGILALSAGLWGPRLRRMLRPLLPHRIPIIPYERWWYTFDQLLKRWSVVPATNDQRRTRWQIWRTLWQKLPKLKPAPPSAHAVRNGLLGLILLASIFTGWRHYAQVQQSPEAVVLAYYDDLDFRRFSAAYARLDPQTRPTYDQYLLELSVQGGLVASYGKLDSVIVNDLGGDQTTRIVDVETRWVTALNEYPTRERLILVKRDSQWYIPTAKVDVRVPPDTFIRQAAIDWFAAGRRRVTTTITSFADVQDRPKLSVLSSRLVSYRGRTSIVGEVLNLDVDPADLTVTGILFDENDRELTRYNAQSVINHKILPKEVTPFRIDFEGVAGAVLSDTLTAGEFNPNAFSPVSFPSPIDHFIVYAKAVVTNRDLNRGLAVQDVVVHAHAEPQQIELTAINNGTEEATIPHILLTYYDANGDVAWVDHAFVASSIRPQRSTVVSIPIIPASAIQIIKTDGDTVVNALVEAGIPDAEPSYFLTLPATTGYSAVRISIHGYFAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX46</accession>
    <name>A9AX46_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2214"/>
    <dbReference type="EnsemblBacteria" id="ABX04854">
        <property type="protein sequence ID" value="ABX04854"/>
        <property type="gene ID" value="Haur_2214"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2214"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095331_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2242-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24737" checksum="7B3DADE72239F1C8" modified="2008-01-15" version="1">MPTTIPALPCADLDQTIAFWSSLGFTVSYTQRKPNPYAVINADDYCLHFFGLKQLAPAENYSTCLIIVPEVEQLHQQFSQHLRTSLGKVPAQGFPRISRMKPGQSRFTLTDNAGNSIIFIKQGVEDEAAAQAYKNPERNPLQRAIAVAARLRDFKNDNQTAAKTLDHALARYPDAPSSDYAQALLARIELAQALEQDQQLEQLTAQLNSIELNPEQRQQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXN5</accession>
    <name>A9AXN5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0801"/>
    <dbReference type="EnsemblBacteria" id="ABX03449">
        <property type="protein sequence ID" value="ABX03449"/>
        <property type="gene ID" value="Haur_0801"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0801"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026152_3_1_0"/>
    <dbReference type="OMA" id="NKTILFP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-814-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="203"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="43926" checksum="FFFBC1C84765318C" modified="2008-01-15" version="1">MKGRRAGLFVLVLLLIIGLLSDVTLLPLVAMLGIMALLAVELWEWRMFKHVDYQRELGHTHLFPDNRTTLSITLRNRKFLPLPFVNLHDLVPVGITLEQIETQPAASPNYRVLARAFGISSYQQVTRQYTILCPQRGLHRFGPANLSASDPLGLSISRATINEIDRLIVYPRLLTEPELGLPLRELLGTIRASQRLLTDPVVPIGIRDYTQSDPLKSIHWTATARRGQLQTRIYEPVTALTVMCILDIETIVPSYLGVNKFQGERLISMAATVCSALHKAGHAIGLWSNAALVEGNTAIQLPPNRSPKQASAILEVLAQMSLYSRLEIAKFIGREQSRLPLGATVLLISAVDTPAHRSALARLREYGYAPVWLYLGQHAPKVAGVKLIHSHQREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS0</accession>
    <name>A9AXS0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0836"/>
    <dbReference type="EnsemblBacteria" id="ABX03484">
        <property type="protein sequence ID" value="ABX03484"/>
        <property type="gene ID" value="Haur_0836"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0836"/>
    <dbReference type="eggNOG" id="COG3597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059930_0_0_0"/>
    <dbReference type="OMA" id="NIDHTDA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-850-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="42195" checksum="E932CC8F575E0454" modified="2008-01-15" version="1">MSRFSDVTNIWSTIKEIDVRDIRDQADLPCRIALLGHATFGRDLIMRLLTLGAQRFPARTPQVSIIDLPLGREQATDLNRVDLIVLTLDASQALSYDEFLAYEKLAILPVPLLIAVWGTNLPKSSESTHQADLQASPAVLLDPQAEPATQRKMLAKAVLELVPEALHIAAARRYPGLRSEVTNNLISSVSLSNATFAFTSGIPEMIPVLNLPLNAADMLVLTKNQALLAYRVALAMGAEGDFSAMIRELLPVVGGGFLWRQLARQLVGLIPGIGLLPKVAVAYAGTFVTGIAAWRWYERGELVSKAELQSLVKAALEEGRQRAKALIGNRKADDDPTASAKPSFRQRIGAVLNPKNWFKALRARLRRKPKSIQKTTEPTDQSNSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY16</accession>
    <name>A9AY16_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4266"/>
    <dbReference type="EnsemblBacteria" id="ABX06898">
        <property type="protein sequence ID" value="ABX06898"/>
        <property type="gene ID" value="Haur_4266"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4266"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054176_1_0_0"/>
    <dbReference type="OMA" id="WMLTGGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4313-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="24"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="274" mass="30700" checksum="3373B5FBA9CC9E45" modified="2008-01-15" version="1">MIDNRGSDRYIIDTPESIEFGYDVAGIGTRFVAAVIDTAFFSILLFIAQRVYIGTDNNPSDAAYRIFFFFCIFTVLVYYIAFERFWNGQTPGKRLLGIRVVQEAGKPLTFTGSLIRNLLRLIDFVPAYYSTGLLTMLIDKRARRLGDLAASTFVVRDRQRVTLEMLLQSTRDDKVASALKDSGATLPNITALRPSDMDLVQNFLLRRAVLAPDRRLRIATQLAYALFGRLGYSVPGDPEQFLQQASDQYVLVRAQALQAAPAPVPVNPYDGHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY41</accession>
    <name>A9AY41_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4291"/>
    <dbReference type="EnsemblBacteria" id="ABX06923">
        <property type="protein sequence ID" value="ABX06923"/>
        <property type="gene ID" value="Haur_4291"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4291"/>
    <dbReference type="HOGENOM" id="CLU_2479074_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4343-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="87" mass="9839" checksum="EE8566290C833949" modified="2008-01-15" version="1">MLVLLRSLHGHSTILATAPSELHGQMINCKKGDHSTCSWRIDWELRFSTSAWQHLDRERLTVKSPRPLVCNGALMRVEDLCKIAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY82</accession>
    <name>A9AY82_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA-4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4332"/>
    <dbReference type="EnsemblBacteria" id="ABX06964">
        <property type="protein sequence ID" value="ABX06964"/>
        <property type="gene ID" value="Haur_4332"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4332"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2865">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020570_0_0_0"/>
    <dbReference type="OMA" id="HIYYAAR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4385-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="777" mass="89166" checksum="6954E56FB0B41FB0" modified="2008-01-15" version="1">MTFSDEQVSAVSERWMRLDLHIHTPASEDYAEPEVSYLDILRAAAAHQLDIIAFTDHNTIRGYEQFRDELALLERFVQADRCTPEERERYGEYQQLLAQLTVLPGFEFTSHYGSHILALFAPTTPLSVLEAVLLQLGIPAQELKAGSCSISNTKHVTEAYEIIHRAGGIVIAAHVNAHAGVVSESIRFGNSGQSRVAATQSPYLHALEFVHFYASHESYLSPNFYNGQHTYYERPMFCIQGSDAHRISRADADDPESKKVYGVGDRYFEALLPEASFDALKALFNSKQIDKVRVPRRDQKQWEIDNVRLNGDSRHLIARPATEEYLAQAWHDIAALANADGGVLLIGTDGEQTVSPTVISEQIKHLVAQHLDPQPSLSLELMQYQERDVVRVEVKTDELPPYVASNGTVYVRRDDQTHVANREELLQLARRALVRSTMSPLDNGEDLELPRSGVEIVSEQKRNAVWTYEVRDLRTTTGVERDRAQGLWAYAIARHEELRDAKIDLNEDVRWYGRLGVWRTFQQGNRTKYDLIHRDASGVIDHIFYGVSEWGLGEGWRSLLGINDNFGVDLNVNDDHAPISTPRGFTAPIDDEQTDGEDDWMPWGDRKYRWKGRGGLWRIYGNDEKIRFDLAMKNKEDEDFQTFNDVTRAKLTEAWLNLIRVKPPTTGIEVVAMEESDFGRSFRFRNLRSGEVSDPWRDQDLEQGTVREYAARMFLEDLPIDEASVRWWGNIGYMRPMRSQVDLVYRDEDGVDHIYYAARREELENEWRELLELWDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY88</accession>
    <name>A9AY88_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4338"/>
    <dbReference type="EnsemblBacteria" id="ABX06970">
        <property type="protein sequence ID" value="ABX06970"/>
        <property type="gene ID" value="Haur_4338"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4338"/>
    <dbReference type="eggNOG" id="COG4214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_1_0"/>
    <dbReference type="OMA" id="VFTTITN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4391-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="411" mass="43171" checksum="C3C304AEF1049DF2" modified="2008-01-15" version="1">MMKTQPTNLAAAPNNWREALAERFRQGNLGSLPVIIGLIIIALVFQSINKNFLTPLNLTNLMVQIAAMGTISTGVVLILLLGEVDLSAGQVSGLAAAVMAVLVSRHNLPAAVAIIGAIVVGALVGLLQGWWISTFRVPSFVVTLAGLLAWQGSRLRVLGDTGSINITNKFINDIANYKLPIWLGWVLGIVSVVVYTLIVFNEYRSRRAAELPTGSLNGVFWRVGVVGASVLAGVAMMSVNRNANAAGNPIQGVPSAVIIFLTFLIIFDFITQRTRFGRYVYAVGGNTEAARRAGINVNRIRITIFMLASALAACGGILAASRLNAANQSSGDGDVLLNAIAAAVIGGTSLFGGRGRIWSALLGALVIGAIANGMDLLALKSSIKFIVTGSVLLLAVTIDAASRARRENSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB6</accession>
    <name>A9AYB6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PpiC-type peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0850"/>
    <dbReference type="EnsemblBacteria" id="ABX03498">
        <property type="protein sequence ID" value="ABX03498"/>
        <property type="gene ID" value="Haur_0850"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0850"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034646_6_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-864-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="157"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="315" mass="34800" checksum="7D1387DBBC418A13" modified="2008-01-15" version="1">MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNASGLDANTTRQQLLDQMILQKVILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYEAFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQFHLFHILLSSDTVSESVALEQANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQLSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRAEEVPFPESVTVFQDQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYM5</accession>
    <name>SYN_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="1">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">asnS</name>
        <name type="ordered locus">Haur_2363</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AYM5"/>
    <dbReference type="SMR" id="A9AYM5"/>
    <dbReference type="STRING" id="316274.Haur_2363"/>
    <dbReference type="EnsemblBacteria" id="ABX05003">
        <property type="protein sequence ID" value="ABX05003"/>
        <property type="gene ID" value="Haur_2363"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2363"/>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_0"/>
    <dbReference type="OMA" id="DNMDLAE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000128208" description="Asparagine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <sequence length="447" mass="50948" checksum="076AFAEBC17B2296" modified="2008-01-15" version="1">MALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEVFARAKELTQESSCYIHGTLRADERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEHRHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPILTATAAEGTSDLFATEYFDLGNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNMELQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGATVAPDNAPLADLEWGDDFGAPHETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCADLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQWYLDLRRYGSVPHSGFGMGIERCVAWLAGTRHIREAIPFPRQLYRIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN2</accession>
    <name>A9AYN2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_2370</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2370"/>
    <dbReference type="EnsemblBacteria" id="ABX05010">
        <property type="protein sequence ID" value="ABX05010"/>
        <property type="gene ID" value="Haur_2370"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2370"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_0"/>
    <dbReference type="OMA" id="TACSIGN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2398-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="4"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX05010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="422" mass="43419" checksum="53AA37E46FF559B1" modified="2008-01-15" version="1">MRRVVITGMGIVSPLGCGVDVVWQRLLAGQSGIGPLPEQISAGLASTIGGMVPSLADDPQAGFEPSAVANSKELRKMDRFIVLGLAAAAEALKQAQWQPQTEEAQERTATLIASCVGGFSTITQAVRTLDSKGPQRLSPFTVPAFLINLAAGHISIRHGFRGPIAAPVTACAASLQAIGDGARLIHSGEADVAVCGGTEAALDPVSLGGFAAARALATEFNDRPSLASRPFDQARDGFVMSEGAGVLVLEDLEHALARGATPLVEVVGYGTTADAYHITSGPEDGSGAARAMRLALRQAQISARDVQHLNAHATSTQVGDRGELAAIKQVFGENSGLAVSATKSSTGHLLGAAGAVEAIFTALAIRDQIAPATLNLDDPDPASEGIDLVAKQPRPMPIEYALSNGFGFGGVNASVILKRWQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV6</accession>
    <name>A9AYV6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate/quinate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4364"/>
    <dbReference type="EnsemblBacteria" id="ABX06996">
        <property type="protein sequence ID" value="ABX06996"/>
        <property type="gene ID" value="Haur_4364"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4364"/>
    <dbReference type="eggNOG" id="COG5322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388768_0_0_0"/>
    <dbReference type="OMA" id="CLAETIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4417-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="691" mass="76146" checksum="CA8BD798B4E1E13A" modified="2008-01-15" version="1">MKEVVCITLGRSRRDFSFTTTLLGEELRVRRIGADGDVERVKQLIREHDGKVDAIALGGVIANFRVGKASYQHNQAYTIVNQARVTPTADGVLLKATLERWTVAQAVSREPGRFNYRRVLVFSGIERYSLAESLSGYNVDLRFADPKVHYGLPFTLSSLSQLERYAKFAMPDLAKKPYRRIHPIGKGATHDSRLEKDCAWADVLAGDFAFIRRYAPQDLRGRTILTDDPSPAEIEDLRQRGAHTLITLTPKISEEHPFVSADVLEAMILAVTGKRTLDEATVLQITADANWEPHIQRLTNDEELEKFAFVIHPLSTKFIYKDPRFKVFKFVPQRWVERAMAHLPPLYLSRMKGIKSTGTGKEIEGILLTLGATPRELMRRPTAFTYRRLIKAARMAERMGAKLMGLGAFTSVVGDAGITVAQKSDIGITSGNSLTVAATLEAAKQAVILMGGRVDQGTAVVIGATGSIGAVCSRLLAQAIGDVVLIAPRPERLIALKKQIEAETPNAKVTIATKADDYVGSADLIVTTTTALNTKIVDIERLKPGAVVCDVARPPDIKEDEAAKRPDVLVIESGEITLPGEVDFGFDIGLPPGTAYACLSETALLALDGKFEDYTLGRNIEMDRVKEMYRLFKKHGLKLAGLRTFDQYVTPEMVAEKRRLADHRRHELGLPVTTESETLTSEMPLEVGGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYX0</accession>
    <name>A9AYX0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4378"/>
    <dbReference type="EnsemblBacteria" id="ABX07010">
        <property type="protein sequence ID" value="ABX07010"/>
        <property type="gene ID" value="Haur_4378"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4378"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_764555_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4432-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="41698" checksum="162ACE6B213CD389" modified="2008-01-15" version="1">MGYAADLCNQATQLFRQGQFRSAASLLEQGIVAARQESDGDNELLCYQKLTAALMNLDQSQQALEVATTMLARARQLREPHYELVATIRLCSALIDLDLKGRWGEIKTLLLDCLQQAQARNTTAWQLDCLRLLASNAMTMQEYDDALQYAQQGLGLIRHDTYSADFYRYVFYRVLQRLHSHREEPAEALRYGLLSFEYAQREGNPAWMITARRYLAHLHYQQGNLQAAFDLFCENVASALAYDSASDHQDATMWRAEIALQLKLGERALDFSREALELARKRLHSRDEAWALLANVRALHALNRADEAWYFANEAYQFAQTQQLEHRQKEAREWIETLTKQQQPPKSATKQGSWFDRLIGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY7</accession>
    <name>A9AYY7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07027">
        <property type="protein sequence ID" value="ABX07027"/>
        <property type="gene ID" value="Haur_4395"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4395"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_7_0"/>
    <dbReference type="OMA" id="INISTMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4449-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15802" checksum="76A338FA3DEA9D03" modified="2008-01-15" version="1">MEAHYHLCFQVGRVARQLISHYNRVLAPLGLTTAQYFVLVAIKPDEAPTMGELSNRTYLDNSTLTPIVDRLERDGWLERMSDPTDRRTTRIQLTSSGLERLPDARQRGDAVENAMREQLGDPLVDLLTDGLRKVARIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ87</accession>
    <name>A9AZ87_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0985"/>
    <dbReference type="EnsemblBacteria" id="ABX03633">
        <property type="protein sequence ID" value="ABX03633"/>
        <property type="gene ID" value="Haur_0985"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0985"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_0"/>
    <dbReference type="OMA" id="DREMGMQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1001-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="132"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="292"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="434"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="704" mass="79143" checksum="47A188DF0B86CA4A" modified="2008-01-15" version="1">MSKASIVIVEDEVIVALDMAQALKAAGYNVIGSFSCGEAALEFIAEQCPDLIVMDIHLQGQLDGISTAEQIQKRYGLPIIYLTAYSDSETLSRAKATEPYAYLVKPFEDRDLLSAIEMGLYRHRVDQRLRRMERLYSSTLNSVDDAIITTDIYGLIKFANPTASSLLNRPNDALIGQFIGDVVQLLDRETKITYQFDLPYLIQQANHHMLLPRQILVNDQAKFVVAPSISQIREEDEAIAGIVLVLRDMRDLDAAEEHIRHQALHDALTGLANRNVFINRLQYILDHYHLHHHHAVLFIDLDRFKIINDSLGHIVGDKLLIQVGQRLERCIRSHDLVARLGGDEFTILLDGVNDIHDVLRVTDRLLSVVAEPYHIDGYKVFTAASIGIVVIDDHYKHYHEVLRDVDSAMYRAKSQGRGCRAVFDEEMHVEALRTLQLEVELRRAVERDELCLHYQPIIKLATGELSGFEALLRWNHPTQGVIGPASFFAIAEETGILAQIGWKLLRESCQQICAWQNEFQFHPPLELSVNFTHRQFFQANLIQQVQSILAETGMPARHLCAEITEGVMMQSNRAVEVMHELHDLGVQVHIDDFGTGYASLSLLHSAPIDVLKIDRTFIQPESGASKHSIAQLISLMARSLGCAVVAEGVEDAQTAQMLIEMGCDFGQGWWYSKALPPEEARVLIRNFAQGTVMVPVPLNAKVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ93</accession>
    <name>A9AZ93_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0991"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03639">
        <property type="protein sequence ID" value="ABX03639"/>
        <property type="gene ID" value="Haur_0991"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0991"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_0"/>
    <dbReference type="OMA" id="VVCVSRY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1007-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="37"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="230"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="346" mass="38434" checksum="1B63452671764A49" modified="2008-01-15" version="1">MLKPLYISPLGKGGVDIGIQNITRSMQRAGHQPSLRRLSHLFNFAPMAAKLALGRNWWQGHDLVQARSRCAWALRAPGLPLVTTVHHIVTDPLLQPYSSPQQRLFYRLVEKTYDGLSVRLADEVICVSRYTQEQTRLTYGDRPTTVIYDGIDTEVFTPAPDFQRTNDLPEHPAPIRLLFVGNRTRRKGFDLLPKIMDQLGPQYVLYYTESFQGVQAAPPHPQMVRIGTPDRDGLIAAYRSCDVLLFPARVEGFGIVAAEAGACGKPVITTNASALPEVVNHGETGLLCELDNVQAFVQAIQELGEDPARRLQMGQAARERVASNFGYDVLARELAAVYRRALFGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZC6</accession>
    <name>A9AZC6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1024"/>
    <dbReference type="EnsemblBacteria" id="ABX03672">
        <property type="protein sequence ID" value="ABX03672"/>
        <property type="gene ID" value="Haur_1024"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1024"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_949671_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1041-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="22"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="35706" checksum="85C6D88041D7A265" modified="2008-01-15" version="1">MQINPALAQAIEADSGFELTQVEFIGAGWFAQAYRFCSQAKHYVVRISKHYHDFLKDVYAYQHWGQQLPIPAILAHGQFADGWAYAISPHIAGQTIVSLEAAELRQIQPALFKSLQQLHQLKLGPVTGWGSVNSQGHGRYQSWAEEVLDIGNYKFDFDWHDWIKRDDQTGTLLRQGYRLMEQLLSTISTERSLIHRDFGFDNVLCQPPTIVAVLDWADFGYGDWVYDIAQQSCYGQAEIYLQPWLKFAQQHDLIPDNFEKRLHCYWLRMNLTDLIVSQLRNDWHWQRKIVAELSWLIENPVVVRLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD1</accession>
    <name>A9AZD1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2435"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05075">
        <property type="protein sequence ID" value="ABX05075"/>
        <property type="gene ID" value="Haur_2435"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2435"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_6_5_0"/>
    <dbReference type="OMA" id="SSHNDAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2463-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="12"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="451" mass="51178" checksum="491C748B2FAA1223" modified="2008-01-15" version="1">MHPWANDVQCYQIYPLGLCGAPIRNDQTSEPIARLKQLHTWIEHLQHLGSNLLYLGPVFESTAHGYDTIDYFTVDRRLGSNNDLQQLIAAFHAAGIRVLLDGVFNHVGRDFWAFRDVQSHGQASSYSDWFAGLDFNQHSPYGDQFSYQGWHGHYDLVKLNLHNPAVREHLFQAVSQWIAQFGIDGLRLDAADQIDHDFLAALAAHCKSLRSDFLLIGEVVHGDYRQWANPTMLDSVTNYEAYKGLYSSLNDRNYFEIAYSLNRQFGAGGIYRAMPLYNFVDNHDVDRIASTLHNPAHLYPLHLLLYTMPGMPALYYGSEWGLLGQKTATSDQALRPALPQPDQIQAQQPDLLAAIRQLSQLRHEYAALRYGEYAQIYVQAEQLVFVRWTKQQTIVVALNAAPTAQTIRFVVPFGEGSLLEDRLNGGEIKVQHGQLQLTIPATWGQIWQLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZE5</accession>
    <name>A9AZE5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ureG</name>
        <name evidence="6" type="ordered locus">Haur_2451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2451"/>
    <dbReference type="EnsemblBacteria" id="ABX05089">
        <property type="protein sequence ID" value="ABX05089"/>
        <property type="gene ID" value="Haur_2451"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2451"/>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072144_1_0_0"/>
    <dbReference type="OMA" id="VDLTIYV"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="PTHR31715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="5">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="23869" checksum="B4655DE0AD70703A" modified="2008-01-15" version="1">MTEQLLRIGIAGPVGSGKTALAHCLTSHLTKRYSVAVVTNDIYTKEDAEFLLRQGVLPAERVRGVETGGCPHSAIRDDASMNLEAIADLCATLPDLQIVFVESGGDNLAASFSPELVDYWIYVIDVAGGDKVPRKGGPGVTRSDLLVINKIDLAELVGASLDVMNHDAKQMRGELPLVFTNLKDETGLDQVIAWIDHVYASPRPEPIHVHDDHHHHHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK1</accession>
    <name>A9AZK1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2507"/>
    <dbReference type="EnsemblBacteria" id="ABX05145">
        <property type="protein sequence ID" value="ABX05145"/>
        <property type="gene ID" value="Haur_2507"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2507"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_4_3_0"/>
    <dbReference type="OMA" id="IICVGEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2535-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="513" mass="55747" checksum="62AD5A77E74AA788" modified="2008-01-15" version="1">MSLLKRLGSTPTSPEPTPPAQPVQPMAGEQSMPEYRSSSLTPLSPPPPAPSSPPMPGGNLSALAGSSSGLSGGTINTSGFLVLADRDAHRKMLELSLWIVDKIQASVGSQTQLQRNEDSERLIQERFTTFVRQSTTNLDQDGTKLLYQMVLDELFGFGPLEQLIRDDTITEIMVNSATVVYVEQKGKLTLSPVIFASEDHVLKVIDRIIRPLGRRVDRKWPMVDARLPDGSRVNAIIPPCAIDGSSLSIRKFSKKKLQVSDLINYGSMTKEMADFLNACVVSAMNLIVSGGTGSGKTTLLNVLSNFIPDHYRICTIEDSAELQLGKDHVIRLESKPADVDGSGLVTIRDLVKNSLRMRPDRIVVGEIRDGAALDLLQAMNTGHDGSMSTVHANTPRDAIRRLETLALMSGLDLPVAVIREQIASAVHVIVQQARLRDGSRKVVAVTEVQGMESGQVVLQDIFIFEDQGTAPDGKVMGVLRPTGTRPRFTPVLEAKGFKLPPSIFGATFPGMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP0</accession>
    <name>A9AZP0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4462"/>
    <dbReference type="EnsemblBacteria" id="ABX07094">
        <property type="protein sequence ID" value="ABX07094"/>
        <property type="gene ID" value="Haur_4462"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4462"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_0"/>
    <dbReference type="OMA" id="DHIDVYR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4517-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="35044" checksum="FD0E780B99E105A8" modified="2008-01-15" version="1">MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFTNEQLVGKAFKGRRDQIILATKFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLYYQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETIRRAHQVHPISALQTEYSLWSREPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNLALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAELAAINAVLPINVAVGTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ5</accession>
    <name>A9AZQ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4477</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4477"/>
    <dbReference type="EnsemblBacteria" id="ABX07109">
        <property type="protein sequence ID" value="ABX07109"/>
        <property type="gene ID" value="Haur_4477"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4477"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469115_0_0_0"/>
    <dbReference type="OMA" id="GVGFNMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4532-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="210"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="344"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="581" mass="64154" checksum="A646136F15972F85" modified="2008-01-15" version="1">MSDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVIVALSSVIFFGFWWWRLQSWRPAPELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFILIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMHFIFMVVSATIAAATIQGIRLRTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERFGEMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLPYSNRVVRVAAVRDITEQRHFENLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYSEMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTITDLDAEVVRLEYETIDLALAIGSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISVQRLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLARALGGTIELDSRLGIGSTFTLHMPEHPTKPNVPSPQMSHANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV7</accession>
    <name>A9AZV7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4530"/>
    <dbReference type="EnsemblBacteria" id="ABX07161">
        <property type="protein sequence ID" value="ABX07161"/>
        <property type="gene ID" value="Haur_4530"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4530"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_0"/>
    <dbReference type="OMA" id="NITITCH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4585-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="72"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="257"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="55129" checksum="EB0FE882C0AD211E" modified="2008-01-15" version="1">MRMAMQLHARGGLALNQLIRLVYLMAIAVGMLGLGLIGYGLWLARFDWWHWFLISLGALWLLLHIGLIVMLQRKRRAIQQLTAVVDVLATADLSVRAPNLGTDELGELAQSINLAAEHFTSLLDTQRRETQRERAILAAIDDGVIVCDQLGQIILLNTAAYNIIAMAEAERLQTNHEQPNLSLRFYAALEAVQPALDQALGRPHIKPAERVCFAGRTYRLSANPIWIDDRRIGAVAILQDISARVESERLRSDFMALAAHELRSPLTSIRGFADMLLWSNPEHFSAEEISYIEGIGRNIQRLTELMNDVVELARLETQRNEHTPQPVDLRQVLSAVLDEFRPRAERKKLQLDCLLPNELPLLSLDPLHIRQISHHLISNAIKYTPEQGQIQIEVQQRIDDILVVVRDTGIGISLREQPRIFGRFFRNDNPLSRAAGGTGLGLSIAKALVEMNHGSIYFESIEEEGTTFYVAFPLALVCEPLPYNPAALADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B025</accession>
    <name>A9B025_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="9">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_1084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 9">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1084"/>
    <dbReference type="EnsemblBacteria" id="ABX03732">
        <property type="protein sequence ID" value="ABX03732"/>
        <property type="gene ID" value="Haur_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1084"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_8_1_0"/>
    <dbReference type="OMA" id="NIAGMQV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1104-MON"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="452"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX03732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="524" mass="55909" checksum="4CAD24A1BA93C460" modified="2008-01-15" version="1">MDRILVTEKIGAEGLAALKEVAEVDVRLDLTPETLLEALPQYDALIVRSQTKVTAKVLAAGTKLRVVGRAGTGVDNIDLAAANQQGILVVNAPASNSIAVAELTIGLMIGLARNIPQAHTALQNGKWERSKYGGWEVRGKTLGLVGFGRIASEVARRARALEMNIIAYDPIINAERAAQLGVTPVTLDELTSRADVISLHIPLIDATRNLFDAQRLSQMKKGSYIINCARGGVIDEEALFEALESGHLGGAALDVFAKEPPTGPIVTHPKAIVLPHLGASTEEAQALTAADVAEGIVDVLAGRSPRYAVNAPFVAPEEWAIVGPYLDLGRKLARLSTQLVDLPAQSYQIVYNGALAGLTSEPIKLAVLQGLLEGGSEGRVTPVNAPFLARERGLTINETHRPDAETYTELLQLVVTTSDGVVHTFGGTVVRGEAHIVQINEFWLDLVPTSSMLFTFHQDRPGFIGRIGTLLGTADINISAMHVGRSSPRGTAIMVLTVDEAIPSETLTDINNQVDIERAYSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B097</accession>
    <name>A9B097_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2568"/>
    <dbReference type="EnsemblBacteria" id="ABX05206">
        <property type="protein sequence ID" value="ABX05206"/>
        <property type="gene ID" value="Haur_2568"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2568"/>
    <dbReference type="eggNOG" id="COG3861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_651767_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2596-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="421" mass="41743" checksum="C3211E02FF4C16E4" modified="2008-01-15" version="1">MTTTVIGVFNSDAQAQAAVRDLQALGITNDAISVVARDTSRAVDADGNLVTVSDDHMTAGEGLTVGAVWGGLVGLAALAIPGIGPLIGAGALVSALTGAVAGAATGGIAGALINAASVPEDQANVYEDRVKAGSTLVTVHANDHMAAQVRTTLRQAGAERFQWDSDTDYDQSNEQAYADSSKVGTVGGGAAGAVTGASIGAAGGPVGAVIGGVTGAVVGGAIGAAGDTTGEKMNDRTHDSDYPHSTAYDTTNAYSSNATYDQMTTVDTTREAIANRDYSTTNDTPVSNRIENAVRDVTTDDQGHDTFRAADQAYDNSSKVGTAGGGAAGAVTGAAIGAVGGPVGAVVGGVVGGVTGAAIGAVGDTVGEQADTETGAFSHDNQAQYRGTANAVGDKLRDAGNSVERKLDRDIDRDGDVGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0S4</accession>
    <name>A9B0S4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TROVE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1146</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ro 60 kDa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1146"/>
    <dbReference type="EnsemblBacteria" id="ABX03794">
        <property type="protein sequence ID" value="ABX03794"/>
        <property type="gene ID" value="Haur_1146"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1146"/>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533084_0_0_0"/>
    <dbReference type="OMA" id="GHMKDMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1167-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040322">
        <property type="entry name" value="TROVE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008858">
        <property type="entry name" value="TROVE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037214">
        <property type="entry name" value="TROVE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14202">
        <property type="entry name" value="PTHR14202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05731">
        <property type="entry name" value="TROVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140864">
        <property type="entry name" value="SSF140864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50988">
        <property type="entry name" value="TROVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="TROVE" evidence="4">
        <location>
            <begin position="35"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="546" mass="61393" checksum="61609C5598E42215" modified="2008-01-15" version="1">MVALLRRVVFLPYNLEVAMNIVRRLFARTPDAAHGLNHEGFPTYQRSLAERYMQTLLTNTIGSTFYASQGSNYALALELHQAMLAHNPLFAAKALVYAREQGTMRLQPIIGLVVLSTVDLGLFHLIFKRIILTPGDLQDFVQIVRSRQIRPGMGRAIKQTINDWLLNLSEYHVIKYGGTNAGSMTLRDVLRLTRPQPIDDRTNALFSYLIDRERWRTTWAEQASTLLPQIAAVEQLKRTSDPTEQRALVEAGRLPYEIVTGTGKPDLAMWRTLIEQMPYLALLRNLASLQRAGVFHDAAMIEYVVGRLGDLEALRRAKILPFRLHAAWLAFTPLSEQEKLIQQTLEQMIEMAFVNMPEIPGRVVVAPDVSGSMRGSINPKSQVRYVDVAGIFAGSLYRSNPTAQLLPFNTSIVQMETWRETKLMWLTKQITAKLGGGTAVSAPISYLYERREVVDVVIAITDNEEWARDSDSGTSFVSVWRKYLAKVNPKAQAFLITIAPYPHAVAPPDEPNVSFIFGWAEHVPAYIAQSLLGYADQLSTIEQITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B106</accession>
    <name>A9B106_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoglucanase</fullName>
            <ecNumber evidence="7">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2646</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2646"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH9">
        <property type="family name" value="Glycoside Hydrolase Family 9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05284">
        <property type="protein sequence ID" value="ABX05284"/>
        <property type="gene ID" value="Haur_2646"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2646"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006010_0_0_0"/>
    <dbReference type="OMA" id="YPWHTCE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2676-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02850">
        <property type="entry name" value="E_set_Cellulase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004197">
        <property type="entry name" value="Cellulase_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033126">
        <property type="entry name" value="Glyco_hydro_9_Asp/Glu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018221">
        <property type="entry name" value="Glyco_hydro_9_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02927">
        <property type="entry name" value="CelD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00592">
        <property type="entry name" value="GH9_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00698">
        <property type="entry name" value="GH9_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="3 5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5 7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM2" evidence="9">
        <location>
            <begin position="702"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="684"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="554"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="603"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="812" mass="85848" checksum="874D35DFA8C4FE55" modified="2008-01-15" version="1">MTVHFQRRKRSRTLIAACSTVALTASVAFGNISSVFGVIQHESRNTTPANLPAAAVAASSLIRVNQHGYLPNAIKRASLVNSSNSPVAWQLRNSSGTTVLSGNTTVFGYDASSGDTIHIIDFSGYTGTGSSFTLAAAGNLSHQFDISSTVYRQLKYDALAYFYHNRSGIAITMPYAGRNDLTRPAGHVGIAPNRGDTNVPCAPGTGCSYSLNVVGGWYDAGDHGKYVVNGGISVWTLLNQYERNQYLGSSAADFGDGRMSIPENSNGVADLLDEARWELDFMLRMQVPAGQPRAGMVHHKMHDANWTGIPLRPDQDSQDRVLRPPSTAATLNLAATAAQGSRIWRFIDPTYSARLLSAAETAWAAARANPNVIALDSDGTGGGSYGDPQVGDEFYWAASELYITTGKAEYKSYLQSSSYYQDVPSDYSSREPAMTWGTTEALGTISLAVVPSGFNSSELAGVRNAVISAATVFANNTTGQGYGTPFNSTSTGYPWGSNSFVLNNGIILGLAHDFTGNVSYLNAMSQGMDYLLGRNAMDKSYVTGYGENPLQNPHHRFWAFQANSGFPRPPAGAVSGGPNSALQDPYAQSIGLPGCNAQKCFVDHIESWSTNEITINWNAPLAWVAAYLDEKAGSVIPPTATPIPPTATPIPATATPRPATATPIPATATPIGPTATATPIVPTATPRPATATPVPTNTPVVPTQTNSSCQVTYTISNQWPTGFTADVVIKNNGAAINGWNLAWTYAGNQFISNLWNGNVSQVGQAVNVTNVNWNGYLGTGATASFGMQASFSGTNAKPTAFSLNGIACSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B157</accession>
    <name>A9B157_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2697"/>
    <dbReference type="EnsemblBacteria" id="ABX05335">
        <property type="protein sequence ID" value="ABX05335"/>
        <property type="gene ID" value="Haur_2697"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2697"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_13_3_0"/>
    <dbReference type="OMA" id="VRSAQMC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2728-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="16"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="11931" checksum="5CD4681FB6169753" modified="2008-01-15" version="1">MYNNQSAEDIAARIAAGEDLYLLDVREPNEWEIASIAGSERKAMSQINDWWGELPKDREIVVFCHHGGRSAQVCQALATQAGFTQLTNMTGGIDRWSVAVDSSIKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B198</accession>
    <name>A9B198_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RDD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4654</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4654"/>
    <dbReference type="EnsemblBacteria" id="ABX07285">
        <property type="protein sequence ID" value="ABX07285"/>
        <property type="gene ID" value="Haur_4654"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4654"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1018906_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4711-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="7">
        <location>
            <begin position="83"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="28761" checksum="7C465969806A6C84" modified="2008-01-15" version="1">MSNPYQPQDPNNPYGQQPQQPQQPYGQQPQQPYGQQPQQPYGQQPYGQQPQQPYGQQPYGQQPYGQQPFVQGGYAVPSAAGMYASWGIRFGAYFLDVLILLIPSVIINLITGIGVTANFNLTGSTSSASSLGMYIIGSLLNLIINIGYFAYFHGTTGQTIGKKIVKIRVIRRTNQPMDFVVAVKRLAITIASTVINLVIGMISFNSIDDIAAGNLSAATASFGFLGIISFVIGIATLLDYLWPLWDGQKQALHDKIADTLVVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D8</accession>
    <name>A9B1D8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
            <ecNumber evidence="11">5.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4694</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4694"/>
    <dbReference type="EnsemblBacteria" id="ABX07325">
        <property type="protein sequence ID" value="ABX07325"/>
        <property type="gene ID" value="Haur_4694"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4694"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_9_2_0"/>
    <dbReference type="OMA" id="VDCGNGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4751-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="256"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="371"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="446" mass="48984" checksum="42F831EBA9C34F9C" modified="2008-01-15" version="1">MQVNPGIFKAYDIRGIYPSELNEDVAFLIGRAFASFLQAETVVVGRDMRTSGPSIFDAVTRGLMHQGADVINIGMVSTDQYYFACTKLGLPGMMVTASHNPKQYNGFKMVKKMPQLLSGDAGIQDLRKLVESEAFDEPTRQGSMSELDLSEEFIESVLQLIDVASLKSLKVIADTGNGMVGPILQRVYERLPVELIGLYLDPDGTLPNHGLDPLQPENRAELEARVVSENADVGFAFDGDGDRFFAIDNRGQFISGDFMTALMGQYFLEKHPGAKILYDVRASWAVPELIGAAGGVPLMERVGHAFIKARMSNEGAIFAGEVTGHYYFGDFNYADSGVIPSLIILEMLSKKGKTLSELLAPLEATYFISGEINTKVADVKAVLATLAEKYSDAEQHTMDGLSVNYLDWHFNVRGSNTEPLLRLNLEARSKELMEAKRDEVLAIIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1F7</accession>
    <name>A9B1F7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-phosphofructokinase</fullName>
            <ecNumber evidence="3">2.7.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fructose 1-phosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4713</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14213"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.56"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.56" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4713"/>
    <dbReference type="EnsemblBacteria" id="ABX07344">
        <property type="protein sequence ID" value="ABX07344"/>
        <property type="gene ID" value="Haur_4713"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4713"/>
    <dbReference type="eggNOG" id="COG1105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050013_0_2_0"/>
    <dbReference type="OMA" id="GETRSNI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4770-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008662">
        <property type="term" value="F:1-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022463">
        <property type="entry name" value="1-PFruKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03828">
        <property type="entry name" value="pfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="9">
        <location>
            <begin position="8"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="34837" checksum="2A4B9F906058B4CA" modified="2008-01-15" version="1">MSIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFLGDQNTELFDKLFAEKQIDDQFIRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAIRATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAAGKQVVLDTSGEALRYGLAASPTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVAIPPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVEQIRADVVIRPCNAQLDVLQRGANQLKGVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N7</accession>
    <name>A9B1N7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1274"/>
    <dbReference type="EnsemblBacteria" id="ABX03922">
        <property type="protein sequence ID" value="ABX03922"/>
        <property type="gene ID" value="Haur_1274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1274"/>
    <dbReference type="eggNOG" id="ENOG5032EMQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617354_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1296-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731790" evidence="1">
        <location>
            <begin position="22"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="161" mass="17276" checksum="F02F19DAF8289B05" modified="2008-01-15" version="1">MKLVRRLASGLMLLMVMGVLAACGGSAAEAPEVRAEKFFSDFAAAFNDPKLSEAATQEKWADTLSKYFVPEQQAAQKTEILTSLQQLGSLGAELNVKVENLKVEKVSESGDDAEIKIASGTMSMSVLGQEQKTDMATEGFGSSGSSTSKMKKVDNVWYIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B224</accession>
    <name>A9B224_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4743"/>
    <dbReference type="CAZy" id="GH57">
        <property type="family name" value="Glycoside Hydrolase Family 57"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07374">
        <property type="protein sequence ID" value="ABX07374"/>
        <property type="gene ID" value="Haur_4743"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4743"/>
    <dbReference type="eggNOG" id="COG1543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008192_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4801-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037090">
        <property type="entry name" value="57_glycoside_trans_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015293">
        <property type="entry name" value="BE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09210">
        <property type="entry name" value="DUF1957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="3">
        <location>
            <begin position="14"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1957" evidence="4">
        <location>
            <begin position="372"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="478" mass="53938" checksum="5EE74446EAACBD54" modified="2008-01-15" version="1">MEKPTTDQPTDLCIIMHAHAPFVRQPGPSSHGEEELHGLMADCYIPLLRGLADLIEQNKAVKMGLAISPILLHQLNDPVVQKHMLHHLDEAIVQAERRLEATKADEHAAYLAQFYLQLHQRTLHVFEKQWSRNVVAMTRELVEAEALEVLGHTATYPVPHLYDRPTLRTQVEIGTIALMHLLGQTPSVLWSAEDPVSPEWEQILKPLDMRALVGTANPELRGQALSWLSEARQTAVITPDQRLLTHIRSVGLGYPGDPLYRAPMEIPMDDGMLSRDGSAYDPFYAYARARMHARHFTAVLSETASNGQPLVIVADMELFGSGWFEGGLWLRTLLEELPSHFRLVTPSTLLKRHKPSVVVPPQHFAGIIDGRLSAAHRQLQAAVAQYPQAYGDREQVLNQAAREFLLAQSGDWDRWVGTPGADYANARRSEHLQKFDWLMQLLPHETLLPVAAREFAALQERDNPFPTLNYRLFGNFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B247</accession>
    <name>A9B247_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonucleoside-triphosphate reductase</fullName>
            <ecNumber evidence="5">1.17.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.17.4.2" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4766"/>
    <dbReference type="EnsemblBacteria" id="ABX07397">
        <property type="protein sequence ID" value="ABX07397"/>
        <property type="gene ID" value="Haur_4766"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4766"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002384_0_0_0"/>
    <dbReference type="OMA" id="FHCNLAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4824-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="4">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="755" mass="85172" checksum="87CB088055972F55" modified="2008-01-15" version="1">MTEQVTLTPLDDRQVAPPTTIIKRDGREVTFDVARIERALTRCFAGLGRQPHTTVAELAQRVVNILAAKYTTTPTVEAVQDTVEVMLQAAGEFEAAKSYILYRAEHAKKREQRPVPEAIRHAFAESDQYFPSPLQKFQFFDKYSRFDYDLGRRETWIETVDRSVNFLREISDNKLDDADYNRVRQAILEMRAMPSMRLLAMAGPAARRNNIAIYNCSYLPVDSIDSFVEALIISMSGCGVGFSVEHKYIEQFPRVKRQSGAPATQYVVEDSAEGWADALRFGLETWFAGNDVTFDLSQLRPAGAPLRIKGGRASGPEPFRQMLDFARSRILARQGSFLRSIDAHDIMCSVGNAAVSGGVRRTAMISLFDYDDHDMLTAKDGDFDRENSQRWNANNSAVWPASGLTQLEIIEQVLAMVKSGRGEPGIFNRQSAIDMRPSRRKPAEFGTNPCGEIILRPYQFCNLTAAVARADDTFETLREKVEVATIIGTIQSMATHFPGLRPQWSENCQEERLLGVDITGQMDSKVAQDPEVQRRLLEIAVEVNREYAEKLGINQSVSITCVKPSGNSSQLLDCASGLHSRWAPYYIRNVRVSTHSPIYKVLRDAGVPMDPENGQTRDDATTWVVHFPVKAPENAITRNSRGAIEQCNYWLQNKLNWTEHNPSVTITYKPDEVMEVMKWIWENREVIGGMAFLPSFDANYAQMPYVEIGREEYEKLAAEFPPIDFSKVYRYEEEDLTTAAQELACMSGACEIDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B249</accession>
    <name>A9B249_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine phosphatase with GAF(S) sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4768"/>
    <dbReference type="EnsemblBacteria" id="ABX07399">
        <property type="protein sequence ID" value="ABX07399"/>
        <property type="gene ID" value="Haur_4768"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4768"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006040_0_0_0"/>
    <dbReference type="OMA" id="NRETFRA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4826-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="43"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="225"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="386"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="560"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="737"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="913"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="1258"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1480" mass="165946" checksum="F63F7FCB8E02D248" modified="2008-01-15" version="1">MTQRTRKPTLKNRVEALEAERHQTQRALDALYRIGLACRGQQDSFELLRTIYQELQTVWNFDACFIALSDQYDDSAYRIAMLADEGVIEFSEHDPIGPLTGYLIRQRQPLLFRDLAIERETIGLPRLLQFGSDKLSRGWMGVPLVIGTSALGVISLQSYTVGAFDETDLDLLTRIANSMAVALENALLSHRQAELTGSLERQIELRNADLFVISDIAAMLTQQLPLTEMFGLALDFMLELMHLNAGVVCSLSGSELQPIVQRGMQHGSLPESFAPLDSIFGVAISSNSAIVDNHTHSKYWQMAQLSHLGTTLAIPLRRHETVIGVLMVGQTEQRAFKTEEVELLQVVSNQLALALEHGNILAQQRRQIAELEALSAISTATVRALNLSTLLHQLNDAIRSFLPVDVFYMAIYDPERQLLTDSIAIEDENEATYLSEEAMPRKGSFTDWVLSKCEPLFLRHVSRDIRHYPTIIRRTIKGSPSESWLGVPMLDANRRPLGVIAIQNYRPYAFSDRDRFFMQSVASQVSLHVLNVQLYQQRERQLAELNALQRISSLLGSTLEIEAMLRAIDAVLTEFLHIDGFFVMLNHPQSHMVEAVYALNREGEGDFRWMIGLIPPEHTPTWEVLHTRKPLRFGDISQETSTEVAPEDNEVRISSDRTKAWLGVPLNDQTTNVIGLIAIQSFQANVFSNRDEQFMAQVGQQLTLAIQNARLFAQRERQLAELNTLKLVGELLNRTMDIHEMFRGLNPLLTSFLKIDGFYILLNNPQTYVIEDLCVVERGELLDYGSMIGTSLPLNTPTAWILRNGKALRFNNTITDIPKLYPELKTVQVNDEVALSWLGTPLINHRGEVLGAITTQSMNASHFSESDEQFMLQVAHQLGLAIQNARSFAQRERQLAELDAQQGITQLVTSTLDLYEMLRSMDLVLRSFLNADAFQVVIGNADRVETAVVLEEGKEVETAVIGHPLPEGSLTRWTYLHVKPLRMNDIYRDWALYPDLQEPPVPTNSGFMHSWLSVPLIASDQPLGVLAVRATRPAAFGPSDEQFLFNVGRQLALSVRNARLYAAEQTAHRTAETMREIARVLNTTFNPDEVLDLILRELRKVITFDSTSVMLPSNNLLRIVARQAQDEQLAVEWRELTFPLDQTSGAGRVMLSGQPLVVPDTVSDPQWTRSPMPSVVRSWIGVPLISKGVVLGVLNINSLQPNAFTQSDTDLAMTFANQAATALEHARLYQESVTRVEQELEIARQIQSNLFPRSLPVAQGVELAALCLPARETGGDFYEVTELRDGRWALMVGDASGKSIPGAMLMAVARSIVRSEAWDHEIPQIVMQETNRWVTMDIPRHTFVALAYATFDTLDYSLALANAGQLDPIIRRANGDLEYATAPGPHFPLGIMANTPYETASYQLEPNDMVLFYTDGVVESKNTSGEMWGFDRFETLLREHDHSLTSAEWVNLVIDEINQFIGDHPQHDDITLVALKVAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D2</accession>
    <name>A9B2D2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1332"/>
    <dbReference type="EnsemblBacteria" id="ABX03977">
        <property type="protein sequence ID" value="ABX03977"/>
        <property type="gene ID" value="Haur_1332"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1332"/>
    <dbReference type="HOGENOM" id="CLU_2584930_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1353-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734501" evidence="1">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="8610" checksum="9EC4312AC9AD9663" modified="2008-01-15" version="1">MALIPLMVTGTAQPRMAALIRATTHLAAAVNGVCASFVGMFKWVDGNAAYRLVDEIDKAADHQVRGIVKQAIEVLLFRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D3</accession>
    <name>A9B2D3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1333</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1333"/>
    <dbReference type="REBASE" id="16525">
        <property type="entry name" value="M.HauORF1333P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03978">
        <property type="protein sequence ID" value="ABX03978"/>
        <property type="gene ID" value="Haur_1333"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1333"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006958_2_0_0"/>
    <dbReference type="OMA" id="FPDNYFF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1354-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="415" mass="47653" checksum="5F19F26327C5E251" modified="2008-01-15" version="1">MPITLKTIELFAGAGGLGLGFLLANHPGVNFRPLCAVDFNVDACTSYNMNMQWLHQNAPHLQTTQASKAYLRKVESLNVNAVKRLFQLQQGDLDILMGGPPCQGYSSSNRQASKETRDELNNMVKSFLDRVQDFSPKMFLLENVQGVTWTASTDEMRIPSEQLSFIDNEEIADVKDYLVHRARELGYHIWYSVLDAADFGVPQHRKRFFLFGIRTDLTTDPNIRLEKFINPYRTSTLTTVAQAIEDLPVINNGEHWKGNNYNPVANGYITMMRSFMNNNVLFDHFTTNHQEYVLERFRNIPEGENWKSIKNIMNTYKNVNKTHSNIYRRLQRNAPSHTISHYRKAMTIHPVQNRGLSFREACRLQSFPDWYRFSGTRESAQQQLANAVPPLLSSKVALAIADYWLSLPHNALMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G6</accession>
    <name>A9B2G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04011">
        <property type="protein sequence ID" value="ABX04011"/>
        <property type="gene ID" value="Haur_1366"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1366"/>
    <dbReference type="HOGENOM" id="CLU_879335_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1387-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="36468" checksum="C2C053FAC6C4E4EA" modified="2008-01-15" version="1">MEDLNINENESVMGIGVRWTKTSHETHKQEESVIDIPESIRANLRNLHALYLYGLPAKLDGNNKVIRKSITYQKSWPSAWHVFDDEMKNRIKTVGIALEIDSQFMLINCNLEGFGRFLYPETQIDTLFNQWVDIGVYDFLNLSDLQRYKNRRKKLGANVNIISMSQVNIGILRAWTYLENCIIRITSSWERLTKYALPAYFGLIPPKKDSEWKTLFDESIPTKIKGNDNQCYFFDAFNKIRIAYIGKTSELKVLRNALIHELSPRPIGAISTSANQPHTLDGLHKLVVVEHDKFREALLLFAGIIRSKTSENQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H5</accession>
    <name>A9B2H5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1375"/>
    <dbReference type="EnsemblBacteria" id="ABX04020">
        <property type="protein sequence ID" value="ABX04020"/>
        <property type="gene ID" value="Haur_1375"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1375"/>
    <dbReference type="HOGENOM" id="CLU_1893321_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1396-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14349" checksum="57C6AF5FA86E61E8" modified="2008-01-15" version="1">MLPMRPNEFTVMQATHTDAMRDHCVLMEPQTSAGRNNKPVITYTDAGSAVCGFNPSTANGVASEEVLDSTAVVITKPTLRLPTGTVIRASWRVRITHRNGQALTSPLAFDIVGDPSTVGTAIVVELATVTREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R1</accession>
    <name>A9B2R1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2874"/>
    <dbReference type="EnsemblBacteria" id="ABX05512">
        <property type="protein sequence ID" value="ABX05512"/>
        <property type="gene ID" value="Haur_2874"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2874"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_5_1_0"/>
    <dbReference type="OMA" id="IVAGDTW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2905-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="37171" checksum="D50BC59F09547448" modified="2008-01-15" version="1">MMTAFCHHSKIVGKKRMLMDKVERLISIIMILLKKELVSANEFAQLFNVSKRTILRDMDALSLANIPIYAVHGVNGGYGIMQEYKVDKRLLSSSDLQNILTALSGLEQIFLPEEVERTIKKIEAMVGQLALNRAIYLSFYAWEGRSELLETLKTCQESILKKRLVLFDYTDKDGTITQRMIEPYELHFSESTWYLKGFCLDRQAYRSFKLARIDHMTMDTRVFPSRDNSTTQGHEAPYLPQLITIKAWIAPSIKDQIIERYGRKNLEVQHSGVLLATMEIPHNQLGFQFLASFGRQLKVVEPQAYVEDFQQYLAQMLAHYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R9</accession>
    <name>A9B2R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase T2 asparaginase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2882</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of a beta-linked Asp residue from the N-terminus of a polypeptide.</text>
            <dbReference type="EC" id="3.4.19.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + L-asparagine = L-aspartate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21016"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="EC" id="3.5.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2882"/>
    <dbReference type="EnsemblBacteria" id="ABX05520">
        <property type="protein sequence ID" value="ABX05520"/>
        <property type="gene ID" value="Haur_2882"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2882"/>
    <dbReference type="eggNOG" id="COG1446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021603_1_0_0"/>
    <dbReference type="OMA" id="YTYDGGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2913-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008798">
        <property type="term" value="F:beta-aspartyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04702">
        <property type="entry name" value="ASRGL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033844">
        <property type="entry name" value="ASRGL1_meta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="196"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="219"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="5">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="30359" checksum="AC1C5F0850E35ED0" modified="2008-01-15" version="1">MPLAIAVHGGAGDIPDSLRPDHAAGIQAALRAGKAVLQAGGTALEAATAAVIVLEDLPAFNAGYGSVLNREGFVQMDAGLMDGTSLDVGAVAAVEGIKNPILAAQAVLKTPHILFAKADAEAVAREAGVEFVDNASLITPRRHAQWASGDRDFKVDSGSTDSETIADTVGAVALDGLGNIAAATSTGGMSGKPLGRIGDSPIPGGGFYADSHAGGCSTTGWGETIARVLLARRAIENLERGMDVQAAAEAAVAVLGQRIEGGEGGLILVASSGQIGAAFNSQRMTHAYWNNLDDQEQIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B324</accession>
    <name>A9B324_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4857"/>
    <dbReference type="EnsemblBacteria" id="ABX07487">
        <property type="protein sequence ID" value="ABX07487"/>
        <property type="gene ID" value="Haur_4857"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4857"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_0_2_0"/>
    <dbReference type="OMA" id="YELTTIM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4917-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="32763" checksum="6EF554655BF63A4A" modified="2008-01-15" version="1">MTHTTPDNFLGLDQQYSTLETSKVVVLPIPFEATVSYGGGTVNGPSAIIEASQQVEFYDREFDTEPAKNWGVHTLPSVEVNDQDPDSAMQSIAQAVEATARLGKLVCVLGGEHSVSGAVAQGLHAVHGDFVTVQIDAHADLRDQYEGSKHSHACAMHRILDVGAGDLLQLGIRSLDISEAHMIKTDPRITTFYSEHVHDGLHLPALRDFVRGKQVYFTIDIDGLDVGLVPATGTPEPDGLTWREVLEITRILVQESAKVVAFDIMELAPIENLHSPNFVSAKLTYKVMSIIMAKQADLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B382</accession>
    <name>A9B382_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04045">
        <property type="protein sequence ID" value="ABX04045"/>
        <property type="gene ID" value="Haur_1400"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1400"/>
    <dbReference type="HOGENOM" id="CLU_2093462_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1421-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="12968" checksum="3A27CA88CC9CBA83" modified="2008-01-15" version="1">MIELLICTLGCAISLATEHLALWDHPWRLRPPITYMIGMLTIIAWFTVFCLLIDPLYVFFGVALLLLSGGAGLVVILGYWLRRVLTVKDQAAFTAGQLSRSVPSPITQDWIDGHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3E5</accession>
    <name>A9B3E5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_1464</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1464"/>
    <dbReference type="EnsemblBacteria" id="ABX04108">
        <property type="protein sequence ID" value="ABX04108"/>
        <property type="gene ID" value="Haur_1464"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1464"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_0_3_0"/>
    <dbReference type="OMA" id="RPWLFAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1486-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="29"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX04108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="39079" checksum="F491445993095DFC" modified="2008-01-15" version="1">MQLMPDTLTQALPESFQLGSMRIFPNMVLAPMAGVTDSVFRRLVLSLGGCGLVVSEMTNAASVSPKAMKRHRLLDYLPEERPISIQLSGNDPDLVATAARFVEELGPDVIDINCGCPSPKVTGGGHGSALLKDLPKMQQMLKAVYAAINIPFTLKFRAGWDEQSLNYIDTAKIAEDAGCAAITLHPRTKVQGYSGDADWSRVAEVVQAVSIPVIGSGDVRTPADALARLEQTGVAAVMIGRAAMANPWIFRQIAQLRAGEPIFVPTPSDKRDLLVRYVDMCAETMVERQALGKLKQLIGQFSIGLYASNQLRRDVQRANEIEAAKAIIANFFEPFISGAVEAVEVPDEIAVIKEGCENGANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L9</accession>
    <name>A9B3L9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2953"/>
    <dbReference type="EnsemblBacteria" id="ABX05591">
        <property type="protein sequence ID" value="ABX05591"/>
        <property type="gene ID" value="Haur_2953"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2953"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_5_0_0"/>
    <dbReference type="OMA" id="FRSIMTH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2985-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="153"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="279"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="422"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="549" mass="61571" checksum="978BDBED25B119C3" modified="2008-01-15" version="1">MGTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREYYGMDSQQLQDLIDADFNQPSYTEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTKHPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRIIENVPGMVYQFLLEPDHTMRFPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYINGQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLSGQMQYLNPAARRLLQLEPTDQVSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQTAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAEAERQRLHEEVIRTQQQALIELSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVAGLLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQQMNVRYRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Q0</accession>
    <name>A9B3Q0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2984"/>
    <dbReference type="EnsemblBacteria" id="ABX05622">
        <property type="protein sequence ID" value="ABX05622"/>
        <property type="gene ID" value="Haur_2984"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2984"/>
    <dbReference type="eggNOG" id="COG3541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084778_1_0_0"/>
    <dbReference type="OMA" id="RWKHAMH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3016-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018775">
        <property type="entry name" value="RlaP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34817">
        <property type="entry name" value="PTHR34817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10127">
        <property type="entry name" value="RlaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="34525" checksum="4A99C041A24BBEC9" modified="2008-01-15" version="1">MQPKLHLALGTHVVLLRTIDNQAKHSVAQVVATPCEHSEYYTVRCVDGTLLQLTRQDFGLRKQFNDPLLGLEQPQLAENRQWIHYRCVVGSRAYGLDTPESDTDWRGFFVPAAAVDWGLATVPEQYEFVETQEHYWEVQKFLNLLLRANPNALECLYTDMVEHASPLALELRAMRHKLLTSRIYQSHNSYVLAQFRLLERDLRTHGSLRWKHVMHLIRLLLSGIHALRHGELRLRHVAEHDQLMAIRAGELEWDTINRWRIALHAEFEQAYAATKLPILPDLAAANAWLLQVRRAQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R5</accession>
    <name>A9B3R5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutL</name>
        <name evidence="8" type="ordered locus">Haur_2999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2999"/>
    <dbReference type="EnsemblBacteria" id="ABX05637">
        <property type="protein sequence ID" value="ABX05637"/>
        <property type="gene ID" value="Haur_2999"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2999"/>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_4_2_0"/>
    <dbReference type="OMA" id="AHERIMY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="208"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="445"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="631" mass="69786" checksum="57172ABB09F6E00E" modified="2008-01-15" version="1">MPIRVLDPTLAAQIAAGEVVERPASVVKELIENSVDAGATEIRVEAREGGKRELRIQDNGCGIASDEVETAFLRHATSKVTEIEDLFSIRTLGFRGEALPSIASVAQVTCLTRTAADEVGTELRIAGGEIQAKTPRGCSVGTTFTIRNLFYNTPARLKFMRSDATEMSQISTIVTQYALAYPNIRWTLLLDGKLALQTPGNGRLLDALIELYGIDVGREMISVDRTSEAEDETVRVHGFVSQPSTFRAARSYMHLFVNQRWIKPQGNLVYMIEEAYHTLLMKGRHPIVALNIELEPEAVDVNVHPTKSEVKFRNQSHVYGALTKAVREALAAQSTIRAWTGFGANESVNRRVELRSPNGERRGSSNDAPLFDDAPAAPRPQVNNYPDDDFDSTVNLPPIAKQARFETPTTSQTSSFLPPQQQAFDPAYAPSMPAPGEAKLPMLRVVGQVNETYIVAESSDGMYLVDQHAAHERVVYERLMAEHQDVPIERQTLMLAQPIELPPAVTRLLSAHLADLEQWGFEAEEFGEGTLMLRAVPSGLHVGQIATALMEIADHLSYEGGATSDDRREKMLTTIACHSSIRAGKTLTHEEMRQLLQQLERCEMPRTCPHGRPTMLQITQGQIERQFGRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3S8</accession>
    <name>A9B3S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3428</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
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            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3428"/>
    <dbReference type="EnsemblBacteria" id="ABX06064">
        <property type="protein sequence ID" value="ABX06064"/>
        <property type="gene ID" value="Haur_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3428"/>
    <dbReference type="eggNOG" id="COG2847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100939_0_3_0"/>
    <dbReference type="OMA" id="MTIEVEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3465-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007410">
        <property type="entry name" value="PCuAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36302">
        <property type="entry name" value="PTHR36302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04314">
        <property type="entry name" value="PCuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735433" evidence="1">
        <location>
            <begin position="18"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="19164" checksum="166301B40ED1A08F" modified="2008-01-15" version="1">MKRLMLGLLVLILAACGSETTSTTAPSTSNGAANTLGSLTIEGSFARPAFAAATIMQTPTMATTPVSPTMGGGMSGGSAMMGSNSAAYMTIRNSGTADNLISASTDVAGKVELHTVVADGDVMRMEQVEKIEVPANGEALLKPGGFHVMLLEVKQDLKVGDTIDLSLTFEKAGTITLKVPVQMPSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T0</accession>
    <name>A9B3T0_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3430"/>
    <dbReference type="EnsemblBacteria" id="ABX06066">
        <property type="protein sequence ID" value="ABX06066"/>
        <property type="gene ID" value="Haur_3430"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3430"/>
    <dbReference type="HOGENOM" id="CLU_2058137_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3467-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14599" checksum="4263E23866D7188B" modified="2008-01-15" version="1">MSAFKHQPTRHWPRHIQAVSWIILIQLALFCPMACIAHCWWWSMPSHSAGAAQHSATMLVCELHAEHSDSAPQPIPPLPAGLAAFYPMVLLLLAGWVLASHGWRGFAQQHALWSTYHPQIITPPPRISAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3W6</accession>
    <name>A9B3W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3466"/>
    <dbReference type="EnsemblBacteria" id="ABX06102">
        <property type="protein sequence ID" value="ABX06102"/>
        <property type="gene ID" value="Haur_3466"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3466"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631304_0_0_0"/>
    <dbReference type="OMA" id="NDQSARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3503-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="116"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="434" mass="49162" checksum="F0F3BAD61C271EE5" modified="2008-01-15" version="1">MSRLSPSVLVIILLVSCLFIYIGPAQYQANQGLVGIILLLIVLIGLFLAFSRGSVAQRESSRNMLGTLTGITAVSCAALLGQQALNGNLLGLMCAPVLLAGVYMVFLAMTARIGQHVEEGEVLLIQRRMDHQHIIRPPGLHSPIVPALEVGVAVMPTYNIQTDVEVEMVDTASLHTVDKIVVDTQSRIIQRFPDDGSSMPVEMRYEGFLKLPYNYPNRDHIFKEIADRRNMDVMQVRMSADFWIEAIQSQLRRDVEEDLRAIIHDNTFYNPEKRSYGKLAPADISARRAEIAAQLKNRVQEKVQQWGIEVLDIGITQVVLNPDRIKAFYRAITADLEIQTANRLSEQEIKRTIAMADAEAYQRKKLAETDLEIQRQRNEIENASSLQMLQDWMNTIIADNPEMKPDDLKHLLTLALDEHEKRKAYREHNLIEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B449</accession>
    <name>A9B449_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peripla_BP_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4952"/>
    <dbReference type="EnsemblBacteria" id="ABX07582">
        <property type="protein sequence ID" value="ABX07582"/>
        <property type="gene ID" value="Haur_4952"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4952"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_756006_0_0_0"/>
    <dbReference type="OMA" id="NGFRMYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5015-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="52"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="40523" checksum="6A5C7A27057A7983" modified="2008-01-15" version="1">MLVPFAVDRSAIAEQFEQGLRSALAPSIHDGMIKDVHVVVEEVGAGVILLEQKIQQLLGNRHIDILVLWLQSGLIEYITPFLERMPRPTLVVNLGENIPRTSEQHPWIVQHSLGLWQAHYALGRWAAEQLSRSTVHALSHYDSGYDLHYALLEGFNQAGGETVGHYLSHVAPDRGNFTPLWHYLAETPSDLLFYTACGPEAKQFLAAWADSPLLGKRSLVVSPMVWFEIEPELRSKLALTTCLPWHPDLLSSANAATNPFEALAQLLGLEAGACLAQALLKSPNSDDQGLLHALSNVAWMTPRGSIERYSSQQTSVPQLYLIQAHPTDQTSNQVIALELATLDLNPLLRTIEQAPRSGWLNSYLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B466</accession>
    <name>A9B466_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4969"/>
    <dbReference type="EnsemblBacteria" id="ABX07599">
        <property type="protein sequence ID" value="ABX07599"/>
        <property type="gene ID" value="Haur_4969"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4969"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_21_1_0"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5032-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="33"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="214"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX07599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="584" mass="64891" checksum="FA082209BD67BB66" modified="2008-01-15" version="1">MTTFTELGLGEATLRAITELGYEEPTPIQAQSIGLMLSGNDIIAQAQTGTGKTAAFSLPTIERIDPKAMGVQALILTPTRELAVQVSDAISAYGKYLNIRALPVYGGQPIDRQLRALKRGVNIVIGTPGRLMDHMERGTLDLSTVRTVVLDEADEMLNMGFVDDIEYILERAPKDRQTALYSATMPDEIARLARKYLRSPQMVTIEREQLTVPQIRQVYYEIGARDKFEVLTRILDLEMPTSAIIFCRTKAMVDELGEKLLARGYGAELLHGDLSQAMRDRVMKRFREEQVEILVATDVAARGLDIEHVSHVINYDIPLDPEAYVHRIGRTGRAGRSGVAVTLVTPRERRQLRTIERMTGAPIQRLRLPTIADVVARRREAFKDNLRELIEQHNEQGGLEQYLVLAEELAEQYSPTDLAAAAFKMMLGEPDLTAEDPLEMVEDEATFDARRGDRRDSRDNGRRGDRRDNGRAGERPGERGGDRAARGPRSGGDRNNGGRSFREEGMTRLFVDIGREQGVRPADIVGAIANESGLPGRAIGAIDIFDNFTFVDVPDEAANRVLAALGRTQIRGVKITPTLARPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B494</accession>
    <name>A9B494_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SAM-dependent methyltransferase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07627">
        <property type="protein sequence ID" value="ABX07627"/>
        <property type="gene ID" value="Haur_4997"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4997"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014042_1_0_0"/>
    <dbReference type="OMA" id="YFPAIRQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5060-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="40"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="37841" checksum="B54868D1B404CAFE" modified="2008-01-15" version="1">MPVVTLTDRIEWAIVARESLFDERHQAGLRLFNGFLEGEPQLVIDLYATTAVVHNYADPPQAGEALVEQVLAWLPTRLPWLEAILVKTRHSDDETAQNGVLRYGTSLATRIREHGVWYALDLTMNRDASLYLDTRNLRQWILANLADKTVLNTFAYTGSLGVAAVAAGAKRVVQTDRNRRFLNVAKTSHTLNGFPIHKPDFQTDDFWLHMNKFKRKDELFDCVIVDPPMFAATDHGVVDLTQNYTKVLNRVRPLMEHNGTIIAINNALFLSGEEYLALLEKICADGYVEVEQYIDIAEDFTGYPTTRLSKPITNPSPFNHSTKIAVLKTRRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C8</accession>
    <name>A9B4C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0033"/>
    <dbReference type="EnsemblBacteria" id="ABX02685">
        <property type="protein sequence ID" value="ABX02685"/>
        <property type="gene ID" value="Haur_0033"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0033"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_0"/>
    <dbReference type="OMA" id="DQALDIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-33-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="302" mass="34013" checksum="B884E509A683F7CE" modified="2008-01-15" version="1">MEIHQLLYFVAVAETGGFSRAAQRCAVSQPSLSQQIIKLEHELGQALFERLGRTIRLTTAGQALLPQAQQLLTQWRSIKQHVSDSVEQHACRLAIGIIPTLAPRFFPNVSQAFQHHFPRTTLSIVEHTTSQLLIQLIEYSLDLLIASGPIEHPLIQIEPLFDEVLLVALPHDHQYAQRSVLQLNDLYHMPLLALHDDHCLSQQVDAFCYEQYLEPQVVGRVTNLTTIQRCVAAGLGMAFVPQSLTQAEPHPNVVYRRLLDAQPQRKIIAAWHHQRPPSSSVLDLLRTNLGASQKAEVKRQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G6</accession>
    <name>A9B4G6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0071"/>
    <dbReference type="EnsemblBacteria" id="ABX02723">
        <property type="protein sequence ID" value="ABX02723"/>
        <property type="gene ID" value="Haur_0071"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0071"/>
    <dbReference type="HOGENOM" id="CLU_914566_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-72-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33349" checksum="29C9AE09C2040F90" modified="2008-01-15" version="1">MQQSPSSTPTPMTFFNLIREAINLLRRYSGLFMGLAALQVGPFLIGSLWLQANGIQARATAQLNVIMAEMQRRIDNGQTGDGMWVLDYPRADIAPYLLALFGFGFISIFIMRNLAMAASVIAVGDHYRQATPRWASVVLSSLRRLPALIAWGCICVLGLVIALFFAIVPILGTILALGLLWFFGVRLSLVPQIIVAEQVNVFRAIHHSWILTRGAFGRITNIWITLVVLLAVLASYITTIISAIAMALFGETSALTIAMTEGFSTVTSIMILPMAYIGFTLLYYDQLRLAYSGIPTNPSITAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P3</accession>
    <name>A9B4P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1565"/>
    <dbReference type="EnsemblBacteria" id="ABX04208">
        <property type="protein sequence ID" value="ABX04208"/>
        <property type="gene ID" value="Haur_1565"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1565"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_801308_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1589-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="174"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="376" mass="42428" checksum="E8C4F17647785F84" modified="2008-01-15" version="1">MDELELIPHVSNNPLAPDFTTVMKQRSAVADQISAQHSFIEYRLRQRPQTIRRHNTDLKIFADFLASIGIVIPVDEQEVPILATEPNAWAEMSVGIVTTFRTWMLNEGYALGSINIRLGTVRLYCRLAHQAGVLSLEAWSRIHTVEGYRRREGDGIDAQREATETPTRLSTKKAAPHILDQSQIRELKRAARNNPINRTPEVGWRDYLIVCLLVDLGMRCGEVVVLKWEHIQGKILLVDRPKVDKVQKHRLIGDTAKALREYQKVIAQPLELKTPLLAAFDHKGNHVGFGISERAIHKRIVQLGKLIGINNLAPHDLRHSWATRVAQTNIPVQALRDAGGWTNLNTPNRYIAQQAVANDGVTLHSDDRLLEDDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T1</accession>
    <name>A9B4T1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3016"/>
    <dbReference type="EnsemblBacteria" id="ABX05654">
        <property type="protein sequence ID" value="ABX05654"/>
        <property type="gene ID" value="Haur_3016"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3016"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533984_0_0_0"/>
    <dbReference type="OMA" id="ANCTIST"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3048-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="303"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="396"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="510" mass="56110" checksum="CA17DB793F3AD3DC" modified="2008-01-15" version="1">MTSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLNALQFEQNRLDTALVSWSTWDDTYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQALVYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLGIVRFQERIVLVAARPIIDSQGQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIPIDEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFLLNRVVISRVLRLSSEIKHVANNLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAEAERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLIPFRDDMLVMPLVGAIDQARANHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEIAQSLVAFGQQLNQLTTFSSLQAGIAWSIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W3</accession>
    <name>A9B4W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3048"/>
    <dbReference type="EnsemblBacteria" id="ABX05686">
        <property type="protein sequence ID" value="ABX05686"/>
        <property type="gene ID" value="Haur_3048"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3048"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_674000_0_0_0"/>
    <dbReference type="OMA" id="RIAYIGQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3080-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="44370" checksum="F2BD6F4FC2F311B3" modified="2008-01-15" version="1">MRRRIRWLLLIGGVVGLGLAVGIGWWQRDQPAVKLNRTLVQDQAGNIQLIDSHNQQLTLTNDASSIVQYIQVTPAPDGQHVAYIQLTPTVIEIRVQAFDGSPARTVFSDFNLRPFYLSWSPNSQMLAFLASGTTMELYVVPADGSEVAHKVRDGQPSYFAWKPDSSALLLHTGGGTPVGNTAVHSVQSKDLTFFKETAGDFQAPAWNADGSARVVVVADGEINQLMQIDQAGQQALSEPTSEGFMFVLSPDRAKVAYQTFGLQTRSGLMIQTIATGKSQSFETARPLAFFWSPDGRSVALLVADARPRGPSGDAGIVKVSRQAQSGVQVHWEVLDVESGQVKRLKSFVPSGPFLNVLPYFDQYAASLTFWSSDSQYLLNNSSDGVWQVHVETGAEQQLTKGAFGVAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y1</accession>
    <name>A9B4Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3066"/>
    <dbReference type="EnsemblBacteria" id="ABX05704">
        <property type="protein sequence ID" value="ABX05704"/>
        <property type="gene ID" value="Haur_3066"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3066"/>
    <dbReference type="eggNOG" id="COG1418">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124473_1_0_0"/>
    <dbReference type="OMA" id="FERMPRF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3098-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="167" mass="19036" checksum="52777F96EDA9F2BA" modified="2008-01-15" version="1">MSALMRLGQLWAALRAKVTPAERALVQQLLASHEYPLFERMPLYDQRHCLDVYTTLVTAGEQDAELLRLALYHDTGKVDRQGRPVSLIWYGIAVVWKQLAPRFYAWAAQKPRWWCRSIYRYAHHGPLGADLAAEAGCSATIVATIRHYHDDAPTGLAARLRWADDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Z3</accession>
    <name>A9B4Z3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">R2K_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3078"/>
    <dbReference type="EnsemblBacteria" id="ABX05716">
        <property type="protein sequence ID" value="ABX05716"/>
        <property type="gene ID" value="Haur_3078"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3078"/>
    <dbReference type="eggNOG" id="ENOG502Z879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040789_0_0_0"/>
    <dbReference type="OMA" id="AHELPGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3110-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041261">
        <property type="entry name" value="R2K_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18299">
        <property type="entry name" value="R2K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R2K_2" evidence="1">
        <location>
            <begin position="137"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="33325" checksum="3268B3254E0EC861" modified="2008-01-15" version="1">MLILFPAEPFNLPHVDAAYAAEVAASAQLRLAWAVIDLEALFDGAIKQALRRVPVASAPTLAIYRGWMLSLAQYQQLAQGLAAKNYQLINDPAAYAACHHLPNVLPLLGDQTPASLVFPQSQGLDAASIAAQAAVYFNQQALIIKDYVKSRKHEWYEACFIPNASDQAQSARVIQTFIERQAEALVGGVVLRAWHPLQIWQTHQQSGLALAYEYRSFWLDGTLLWATPYWDHQPSQPTPDWSRYTALAQQIQSRFWTLDLALTQTGDWLIIELGDAQVSGLPDHADAQELLQALAQQLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B564</accession>
    <name>A9B564_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mur ligase middle domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3565"/>
    <dbReference type="EnsemblBacteria" id="ABX06201">
        <property type="protein sequence ID" value="ABX06201"/>
        <property type="gene ID" value="Haur_3565"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3565"/>
    <dbReference type="eggNOG" id="COG0769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022308_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3602-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="2">
        <location>
            <begin position="153"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="1">
        <location>
            <begin position="388"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="538" mass="58080" checksum="34E434CA1774E5D2" modified="2008-01-15" version="1">MLEFRDIRALEGPNGYDHAPVALVRLVGETVEIDAWLKQVALACANYGIAHTEPVLQQHPSLGEYAITWRTATPESLALLLEQLAGTDAAASSAEIQAMLEQEQIPNPLHDLAKQHLPLWREAEAWWVGYGRYRQNAAQFDLSTYQTLPIIAISGTNGKTTTTRLIDFSLRTAGYQTGRTDTDGVWINNQAIEQGDWTGFGGAQRVLSHPAVEVAVLETARGGLLRRGLAFNHCEIAVLTNVADDHLPDRGLATVAEMAHFKATIVRAAQKAVILNADDPVLVEVVAPQATAPIIWFSLQATNPLIVQAQQNQQACLYLDANQLILASAGQTQALIAVAELPLSFGGVAQHNIANALAAAAALFAFGLSAGQIALGLAGFQPNAEHNPGRLNQFQRDGITLLIDYAHNSDGLRVLLASAAPLRAANRHIAMVFSGTGDRTDQQIQEQMTIIAQHVDRLILKRDPWFLRGREPGVLEPLMIAAATAAGLDPAAIAELEGDEAAFNELTQPAKAGDVLIWIVYKDRASKIAIAQAWERNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C5</accession>
    <name>A9B5C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0098"/>
    <dbReference type="EnsemblBacteria" id="ABX02750">
        <property type="protein sequence ID" value="ABX02750"/>
        <property type="gene ID" value="Haur_0098"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0098"/>
    <dbReference type="eggNOG" id="COG4990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069568_0_0_0"/>
    <dbReference type="OMA" id="FNAHNLV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-99-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026935">
        <property type="entry name" value="BtrH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032369">
        <property type="entry name" value="DUF4872"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14399">
        <property type="entry name" value="BtrH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16169">
        <property type="entry name" value="DUF4872"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BtrH_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4872" evidence="2">
        <location>
            <begin position="152"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="35776" checksum="7E82F37EF81C3B8C" modified="2008-01-15" version="1">MLAIKPFIGQHCETTTSGTLLYQQGIELSEPLLFGLGEGLSFIFWHMNSMPMPFIGGRVKPDQLTETLAKQLNLKLERQETSSSTKAWAIVKDLLDQGQVVGLKLDCFYLEYFSNPIHFAGHYVAIYGYDHDHAYLVDTHQQGSIVQTSLASLAQARAAKGSMASKSMAYTLKPQGSYDLAQAVRQAIINNAQAYLNPPITNVNYKGIRKASAALQPWFEASANIEYDFCTTALLMERAGTGGSLFRKLYRDFLAEASTIIAAPQLRQAEPTFTTISENWQEVANLLDQAGKQHDLGAIQKASRLMNQIAEQEYTAMHLLATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U8</accession>
    <name>A9B5U8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ordered locus">Haur_3103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3103"/>
    <dbReference type="EnsemblBacteria" id="ABX05741">
        <property type="protein sequence ID" value="ABX05741"/>
        <property type="gene ID" value="Haur_3103"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3103"/>
    <dbReference type="eggNOG" id="COG0341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050012_0_0_0"/>
    <dbReference type="OMA" id="AFEWRMA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="35589" checksum="7CC746E6F0B45B15" modified="2008-01-15" version="1">MLDLVRRRYLWFAISILTIIPGLISMLVFGLNLGVDFSGGARWEIHIPSISETRDGLENDVNAVFAESGIEGARTQLSQGTTNNQQFVIAFVRSKSVQSDSAERKAVETGLTSKFGADTRIETVQTVGETVRGRSIRNAIVAVFIASLAIMGYLWAAFRGTPNPIRYGVCAIIAMLHDVLVVIGMASILGWLIGLEVDALFMTAVLTVISFSVHDTIVVFDRVRENVRRSSDDYERVVNRSIVQTLTRSINTQFTSFFTLTALLLFGGESIRSFVLILLLGLISGTYSSIFNAAQLLVVWENREWRNWFGRGKDKVKPATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Z2</accession>
    <name>A9B5Z2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3148"/>
    <dbReference type="EnsemblBacteria" id="ABX05785">
        <property type="protein sequence ID" value="ABX05785"/>
        <property type="gene ID" value="Haur_3148"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3148"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3180-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="11"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="15568" checksum="31D20E921B977E5E" modified="2008-01-15" version="1">MLKSKEAGIATLVVIEDQPDTLLIIRSTLHQQGHQLHFFPNGRVATAQAVQALHPALILLDVQLPDQSGFDLIGSLRSIAPCIALTGFSDMSIVERAKALGFFGFLGKPIRPAYFPQQISRLLAGEAVWEHTWAGDVPVPIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B612</accession>
    <name>A9B612_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3168"/>
    <dbReference type="EnsemblBacteria" id="ABX05805">
        <property type="protein sequence ID" value="ABX05805"/>
        <property type="gene ID" value="Haur_3168"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3168"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048478_0_2_0"/>
    <dbReference type="OMA" id="HCPGQVC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3200-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37730" checksum="2618AFA0A0838B90" modified="2008-01-15" version="1">MEQRVLRFETHTGVRIYSLPVEVFPQFYANVYLVIADGLVCLIDTGSGHGNSNTDLVAGFAAIQALWGEKLSLADVNQIILTHAHIDHFGGLGFVRQFTQAPTAIHIADRRVITNYDGRLLFASKALSRFLRHAGVSAEQHQHLMGMYLHNKDAFRPQPIEQTFEDGDRLCNLFEVIYTPGHCPGQVCLRLDEVLFSADHILARTAPHLAPEMITPGTGLEHYISGLRQVAKLDGIELTLGGHEQPIENLAQRLEQIFASNQRKIDRISDLLKAQPQTVAQLSAAMYRGLQGYDQLLGIEKVGAFVEYLYLRGYVRPVNIAPDNDDRDPINVMYELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C3</accession>
    <name>A9B6C3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0174"/>
    <dbReference type="EnsemblBacteria" id="ABX02826">
        <property type="protein sequence ID" value="ABX02826"/>
        <property type="gene ID" value="Haur_0174"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0174"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_591704_0_0_0"/>
    <dbReference type="OMA" id="NTELGQD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-177-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="306"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="456" mass="51069" checksum="5B824CA57DE57EBC" modified="2008-01-15" version="1">MSTYVIDGQELHIRDNRRNAPVALLIHGWSSSWFTWTPLLQALGTRYSYMAVDLPGYGRSPAPKHPITIDWYADLMAKLIEEASDRPVVVLGHSMGGQIAMTLALRHPMLVERLILLNPVVSGRLSTFINLFVAPHILLERTRLGGKILSYLENTPLSYINQLMKPILFAERAAISQQDYDRIRADARRPGQGRVRAACYEAMKMGDLRGKLKQIQPPAQVIWGAEDNTVPLRDAGAVADEWPQADLRLIPNAGHWPHFEQYETTMRYIASFLGLPILPSLPNDQVQQQRDLDVGEIAQFLSNTELGQDLSESQRLRVAGLCHQHHFAPQDVLALEDSSGDELFIVQDGQVDVLVRISNELGIEESRRVNVLMAGQIAGEMALIQGKGGRRTADLRAGKSGATVLSIDSRYLFALFEDDASLGLKLMQNLARSLVQRLRVQNWQLQLAEQRAEVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H9</accession>
    <name>A9B6H9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0230"/>
    <dbReference type="EnsemblBacteria" id="ABX02882">
        <property type="protein sequence ID" value="ABX02882"/>
        <property type="gene ID" value="Haur_0230"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0230"/>
    <dbReference type="HOGENOM" id="CLU_2537943_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-233-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="83" mass="9912" checksum="A86E0CC2BDF1A402" modified="2008-01-15" version="1">MNGFVIGLTLTMIVGGLVLIIGPIYLRRRWDNETQRNWEHDEFDRKVKRYNDDIANRQRDYDIVNVLSGRETPTVVDRYRDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K0</accession>
    <name>A9B6K0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcxB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0251"/>
    <dbReference type="EnsemblBacteria" id="ABX02903">
        <property type="protein sequence ID" value="ABX02903"/>
        <property type="gene ID" value="Haur_0251"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0251"/>
    <dbReference type="HOGENOM" id="CLU_1452583_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-254-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025588">
        <property type="entry name" value="YcxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14317">
        <property type="entry name" value="YcxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="119"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="21929" checksum="946C62B3F03594BF" modified="2008-01-15" version="1">MQPTELNYQLNFNDYQEANLSIFKHIPKYQEALNLNRYYVLLLYVLGIGMLAFFVAALFQFDRLSVWLIVFGLILIGIWVIYTNRDMREFTLDYFKKSYQLEKANFESPVRLTVYPTYVQQINAFSSVEFKWLFIQAILDEAEHIILVTHNNRVVVIPKRAFKSPADQQIALQQFAQYHADAQLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K8</accession>
    <name>A9B6K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate ABC transporter, periplasmic sulfate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic sulfate-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0259"/>
    <dbReference type="EnsemblBacteria" id="ABX02911">
        <property type="protein sequence ID" value="ABX02911"/>
        <property type="gene ID" value="Haur_0259"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0259"/>
    <dbReference type="eggNOG" id="COG1613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055615_0_1_0"/>
    <dbReference type="OMA" id="KDFGGWK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-262-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902358">
        <property type="term" value="P:sulfate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01005">
        <property type="entry name" value="PBP2_CysP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005669">
        <property type="entry name" value="Thiosulph/SO4-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30368">
        <property type="entry name" value="PTHR30368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00971">
        <property type="entry name" value="3a0106s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732530" evidence="6">
        <location>
            <begin position="24"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="37030" checksum="B0E2CC683186F1C5" modified="2008-01-15" version="1">MKRLHFSLLSLLLVGLLAACGEASQTTTSNATVTTITLGAYTTPREAYAKLIPLFQAKWKADTGGEVKFEESYQGSGAQSRAIVEGFEADIAALSLEADINRITDAGLITHDWKAGTHSGMVSTSIVVFAVREGNPKGIQDWADLAKPGVQILTPDPRTSGGAQWNILALYGAAKRGQITGVPANDEAAAQAFLASVLKNVVVFDKGARESITNFEKGVGDVAITYENEILVGQKGGQTYQMVIPTSTILIENPIALIDKSVEKHGNRQAVEAFINFLHSREAQEVFAEFGLRSVDADVAKATAERYPAINDLFTINEFGGWSKATPEYFGDDGVYAKVLAQVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K9</accession>
    <name>A9B6K9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0260"/>
    <dbReference type="EnsemblBacteria" id="ABX02912">
        <property type="protein sequence ID" value="ABX02912"/>
        <property type="gene ID" value="Haur_0260"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0260"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432626_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-263-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="632" mass="68874" checksum="9C07764585D9F946" modified="2008-01-15" version="1">MSIVLDQLTKRYEHHTVVNRVALQIHDGEFFVLLGPSGSGKSTILRMIAGLAPVDTGRIVLHGRDVTDLNPQARDVGFVFQNYALFEHMTVDENVEFALRIRKVERKQRTERRDQLLDLVGLAGLGKRLPRQLSGGQQQRVALARALAHNPAVLLLDEPFGALDAKIRTDLRRNLRSIQRELGITTIFVTHDQEEAFELADRLGVMNMGRLLEVGTPNELYQRPQTEFVATFLGSANVLLGQCNDIGVQVGSMTFPLQTSSPAEHHPAVQVVIRPEDVVLARTEAALRCPALGQATVETQTFVGAFERIRLRLPALPDVHSIAPVRPFGEQAILIDALRNPDEARNLPIQSGDQLWIGVRRLHALSQRGLNVLMLADNQPVAETALNIGGNLARLAHARATVVARDGSEASLRARIQAVREQLGAGLPHLQTRLSTASLIETVRKETEHEPCDIVVLGTEARNAERDATQLLSVAQQHVLLVPPSAKPCNKALICVSDGEPSKEDVAFAGRLLGSVGASATLVSVASHSNDIERLERFLQTSAASLRRHEVVTETKVLVGNVAQTINAEIKRGGYDLVIVGAPLGAYSSNYDLGSVVGPLLSQISVPVLIIRSSYLQPMPERLALNVLETVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L8</accession>
    <name>A9B6L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1684"/>
    <dbReference type="EnsemblBacteria" id="ABX04327">
        <property type="protein sequence ID" value="ABX04327"/>
        <property type="gene ID" value="Haur_1684"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1684"/>
    <dbReference type="HOGENOM" id="CLU_1018513_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1708-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="273" mass="31572" checksum="149ADDAF148EFF52" modified="2008-01-15" version="1">MRWLSYFFLIVILLGLSIIVIAVAPIFGLVITGSLVIVLYLVFYLWPIIGAWLSWYSLGLIYQPKKKLRYWGFAILSTIYGLGILCLTIHDLWPFGDWILLGNSLGILVRSGLYEWRVAQGRLRRLSINLLVAVILPLTVKAFVEYPLIKAQDCMMQVALDQTAEKLAQRQLQHGKYPPYLAFDLEFDANALDGQCQALLQKTDRSSLSIADYEYSTWLYQPTATGYRLGYWSRAIRLLESTLFYRVCWYDPSTQRSDCQFTTEEIVYQFKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R6</accession>
    <name>A9B6R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1732"/>
    <dbReference type="EnsemblBacteria" id="ABX04375">
        <property type="protein sequence ID" value="ABX04375"/>
        <property type="gene ID" value="Haur_1732"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1732"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_3_0"/>
    <dbReference type="OMA" id="CPKGISL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1759-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="27724" checksum="6E081BCCC0ADDC21" modified="2008-01-15" version="1">MKLKLHIWRQDNAKTAGKMVSYDANHVSPDMSFLEMLDVLNQELITKGEDPVAFDHDCREGICGACSMVINGIPHGPQRATTTCQLHMRSFKDGDEVYIEPWRAEPFPVIKDLAVDRAALDRIIAAGGFISVGTGSPPDGNAIPISKEISDLAMDAAACIGCGACVAACPNGSAMLFTAAKVSHLNLLPQGEPEKDQRVINMVAQMDAEGFGNCTNYAECQAACPKEISIQFIAKMNRDLIRAKLREGNNAGSGKTGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B711</accession>
    <name>A9B711_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3242</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3242"/>
    <dbReference type="EnsemblBacteria" id="ABX05879">
        <property type="protein sequence ID" value="ABX05879"/>
        <property type="gene ID" value="Haur_3242"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3242"/>
    <dbReference type="eggNOG" id="COG0382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029423_0_1_0"/>
    <dbReference type="OMA" id="RWFLITT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3277-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="34993" checksum="B1426C5056C9E4CD" modified="2008-01-15" version="1">MQQPYKAVQPQFSKMPKYLLLTMRPKQWVKNIFVFAGLIFANDLLLTNPQSLLRVLATFGLWCLIASSIYLINDLVDIEKDRDHPKKRYRPLASGHLAPSSAIVATLIFLVIGLPLAWMLSREVAIILAVYVVMQLAYSFRLKHVVILDVFIIAAGFVFRTVSGAVVLGIDISPWLLICTGLLSLFLALAKRRHELVLLETGAGSHRRVLDEYSTELLQEMISLITASTLIAYILYTLNPTNPHIPTSPFPLMLITVPFVIYGIFRYLYLVYKKDEGGSPEELLLKDLPMLADIVLWGITVVSISYIFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B777</accession>
    <name>A9B777_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06360">
        <property type="protein sequence ID" value="ABX06360"/>
        <property type="gene ID" value="Haur_3724"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3724"/>
    <dbReference type="HOGENOM" id="CLU_2023983_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3766-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="13833" checksum="A3808747B2BAB2F3" modified="2008-01-15" version="1">MEVVMQNLVNDTMNSIMIWTIGGLVFSFVLIVVLRRAFGPNKKLLQQGLPGQATIINVYQTGMMVNNNPQIGLVLQIDGPLGQYQTETKAVIPMISIPQFQPGAVLPVKIDPSNRNNIALDIYGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7B8</accession>
    <name>A9B7B8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoprenylcysteine carboxyl methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3765"/>
    <dbReference type="EnsemblBacteria" id="ABX06401">
        <property type="protein sequence ID" value="ABX06401"/>
        <property type="gene ID" value="Haur_3765"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3765"/>
    <dbReference type="eggNOG" id="COG2020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065200_5_2_0"/>
    <dbReference type="OMA" id="NRRGEWW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3807-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="16521" checksum="A1193D1EFA516BEA" modified="2008-01-15" version="1">MRSTIYVVIQFMCLGLLAISTPLNTLPNLWLLGFGLGVGLGVWAIISMRIKNLSIMPEPLNNAQLTVNGPYRWIRHPMYTALVICSLALVMLEPQVWRWLVIVLLMINLWFKAHYEEQLLSQRFANYASYQQRSKRFIPWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F3</accession>
    <name>A9B7F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0274"/>
    <dbReference type="EnsemblBacteria" id="ABX02926">
        <property type="protein sequence ID" value="ABX02926"/>
        <property type="gene ID" value="Haur_0274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0274"/>
    <dbReference type="HOGENOM" id="CLU_1530501_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-277-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="175" mass="17607" checksum="FDE56A755543DC5A" modified="2008-01-15" version="1">MVIGVLFTCGGLVTTGAGIFINRFVAEQLRSQQITTPADASIPNAPVTGIATALSMAALIQHHAADSSNGLSYAQMGRFAVASGDPSGTNTVDAALKDAKGQPVANQARTTQLTAAGLVTSLSLSAMALGASYGAMALGLGFFILGLIITGLGYALRGLITPEVAARFGIQPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J3</accession>
    <name>A9B7J3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02966">
        <property type="protein sequence ID" value="ABX02966"/>
        <property type="gene ID" value="Haur_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0314"/>
    <dbReference type="HOGENOM" id="CLU_684711_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-317-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732583" evidence="1">
        <location>
            <begin position="26"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="43423" checksum="71DCF15698F241DA" modified="2008-01-15" version="1">MVARQIVKAVAAGLLVVGLSTPAFASGTLTNKFTDYNTVDVKDTVNVMDYGMATAIGDFDDIAGVQTFVSAVRKDDGNLRVSAYYVNTTTNTKLGADIEDGGAMNDVAIDRVGSSGLVVAAVEMNDRSLKFIAYDVTTGTNGRTIDRLNDHIPSIPDLSFVSDVQIARVGSLNRGQFVTIVRRQDGTMRLDSWKVVRNNNNTVTFTWLDFVDGGLQIGDEIAMIRNTTNLWQFATVHKNSNDLMNIRVWNVDQDASGSINFLSGVVYGTSIEGFDVAFSSQRLLTARYKSDGTTVIEMWNVDPFTNQISLDASGSLSTGSSNGVQIFDMGGGDLVLLRENILGSLFQNTLSTSGSVITLDPGGDQHMFTDGFSGVDGGDGRLFYAIADADVNKLTHQLWLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M1</accession>
    <name>A9B7M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Deoxynucleoside kinase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0342"/>
    <dbReference type="EnsemblBacteria" id="ABX02994">
        <property type="protein sequence ID" value="ABX02994"/>
        <property type="gene ID" value="Haur_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0342"/>
    <dbReference type="eggNOG" id="COG1428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1286817_0_0_0"/>
    <dbReference type="OMA" id="RWTATIT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-345-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="dNK" evidence="3">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="9"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="138"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="203" mass="23310" checksum="D809F1242D429325" modified="2008-01-15" version="1">MGKLITIVGNAGIGKTTLTKLLCRDQRFFAALESHVERPFQQLFAQNLQRYALANQFDYLLLRAEQERFIRAQSGIGVQDGGLDEDFWVFTQHFQHQGYLSAAEFELCQRLYTELRAGLGQPDLIIKLDAPLDVIIQRYEQRNRPLEIAQRDDLAQLGTLLDRWTATITTPLLSLDWSSSALPTIEQQQQLIETILKQLRIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R2</accession>
    <name>A9B7R2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1797"/>
    <dbReference type="EnsemblBacteria" id="ABX04440">
        <property type="protein sequence ID" value="ABX04440"/>
        <property type="gene ID" value="Haur_1797"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1797"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_3_0"/>
    <dbReference type="OMA" id="RAWNDRS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1825-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="36002" checksum="CD18A2A8426517EE" modified="2008-01-15" version="1">MDYRDLGRTGWQISTIGFGAWAIGGDAWGKTDDATSLATIHTAIDAGVNFIDTADVYGDGHSERLIAQVLRERPGEIVVATKAGRRLNPHTAAGYNRENLTAFVERSLHNLNTEALDLLQLHCPPTDVYSMPEVFEVLDNLVRAGKVRYYGVSVERVDEALAAIEYPNVQSVQIIFNLFRYKPIEQFFAAAKAKRVGILARVPLASGLLSGKISAATTFEASDHRNYNRHGESFDQGETFSGVDYATGLQAVEELHALVPIDVSMAQFALRWILMFDAVTTAIPGAKTPEQMRANAAAAELAPLDAATMAQAQAIYDRLIRPLVHERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7T9</accession>
    <name>A9B7T9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1824"/>
    <dbReference type="EnsemblBacteria" id="ABX04467">
        <property type="protein sequence ID" value="ABX04467"/>
        <property type="gene ID" value="Haur_1824"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1824"/>
    <dbReference type="HOGENOM" id="CLU_3008107_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1852-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025844">
        <property type="entry name" value="Herpeto_peptide"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14409">
        <property type="entry name" value="Herpeto_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="56" mass="6080" checksum="44A8278D768B7383" modified="2008-01-15" version="1">MEFETTQINETPMIFGLTYLEEEAAEIDDVVGCFVVDGYSGTGCDDSDMPPGTQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7X9</accession>
    <name>A9B7X9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ornithine cyclodeaminase/mu-crystallin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1864"/>
    <dbReference type="EnsemblBacteria" id="ABX04507">
        <property type="protein sequence ID" value="ABX04507"/>
        <property type="gene ID" value="Haur_1864"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1864"/>
    <dbReference type="eggNOG" id="COG2423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_3_0_0"/>
    <dbReference type="OMA" id="YRMAGAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1893-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023866">
        <property type="entry name" value="SbnB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="PTHR13812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03944">
        <property type="entry name" value="dehyd_SbnB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="332" mass="35855" checksum="514FB0B8409C5C47" modified="2008-01-15" version="1">MQQSLTLLKGHEVGRILDGAELTLIDLVRVAYEAHQAGLSSLPHSSFLRFPNDPLNRIIALPAYLGGAQPSAGIKWIASFPGNLSHGIQRANATITLNDPQTGLPIAFMEGAQISAKRTAASAALAAKYLHSNPQETRVGLVGCGVINHETLRFLLAVFPSIREVLVFDTQPAHAEHFQAACSDQFGMNVQVVASIEALLQRTSLIALATTAITPHIDDLSMCAAGTTILHTSLRDLNPRLIEFCDNVVDDREHVLRANTSLDLAQQALGHHHFVRCNLAEITSGQVPARPNPEQTTIFSPFGLGVLDLALAQWVLGQAREYTIGLTLNDFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B804</accession>
    <name>A9B804_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3301"/>
    <dbReference type="EnsemblBacteria" id="ABX05937">
        <property type="protein sequence ID" value="ABX05937"/>
        <property type="gene ID" value="Haur_3301"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3301"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_2_2_0"/>
    <dbReference type="OMA" id="DWSNGMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3338-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="377" mass="40487" checksum="39CA60BC4881D913" modified="2008-01-15" version="1">MTRHFAIVDTTLREGEQWANAHFSSEDRLAIANLLVQFGVEYIEMTSPCASPQSTADLRSIAALPLGNTKLLTHTRCNLDDVRLAAECGVAGVNILFGTSPYLRQWSHGRSIEAILEEVGPVVRFLQERNIEVRFSCEDSFRTPLPDLLRVYQAVDLLGVQRVGIADTVGIATPRDVERVVGAVRNAVRCDIEFHGHNDGGCAIANAYAALEAGATHIDTTILGIGERNGIAALSGLIARLYLSEPESVAGYALPMLAQLDHTVAAILGIQVPFNACITSETAFAHKAGLHTKAVLANPSTYEAIDPKAFGRERNVLIGHRLTGRHALQSRANTLGLDLSDTTIIAIAAQLKAAADDQPLTLDEVDALLRSSTLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B837</accession>
    <name>A9B837_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_3334</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3334"/>
    <dbReference type="EnsemblBacteria" id="ABX05970">
        <property type="protein sequence ID" value="ABX05970"/>
        <property type="gene ID" value="Haur_3334"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3334"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_0"/>
    <dbReference type="OMA" id="FWDSGER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3371-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="8"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="179"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX05970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="32450" checksum="88024DAD3F3AC8BF" modified="2008-01-15" version="1">MARIYDNITQLIGNTPLVRLGKVNTTGATVLAKLEFFNPASSVKDRIGLAMIEAAEAAGLINPNDTTIIEPTSGNTGIGLAFVAAAKGYRIVLTMPETMSLERRKLLKGFGAELVLTPGSEGMPGAIRRAEELAAENPGSFIPQQFKNKANPAVHQRTTAEEIWNDTDGAVDILVAGVGTGGTITGVASVLKERKPGFKAIAVEPTASPVLSGGKMGPHKIQGIGAGFVPDVLDTSVIDEIIQVTNEHAFEWARKLAHEEGLMVGISSGAAAWAALQVAARPENAGKTIVFIVPSNGERYLSTPLFDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H6</accession>
    <name>A9B8H6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07640">
        <property type="protein sequence ID" value="ABX07640"/>
        <property type="gene ID" value="Haur_5010"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5010"/>
    <dbReference type="HOGENOM" id="CLU_2058138_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5073-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="14085" checksum="30A55D0E62BF640E" modified="2008-01-15" version="1">MHQRYGSTATIYLSLSIRRRAKRVIDDLAQSSPNEYITLREAAYEYDMEYNSILKYVLAGRIASRILLPEEIPDVLWQRLEPRVQANVKKHQGLRVTTTQAMEEYMRTRQKRGKKRRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8M1</accession>
    <name>A9B8M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5057</name>
        <name evidence="3" type="ordered locus">Haur_5220</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07685">
        <property type="protein sequence ID" value="ABX07685"/>
        <property type="gene ID" value="Haur_5057"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07847">
        <property type="protein sequence ID" value="ABX07847"/>
        <property type="gene ID" value="Haur_5220"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5057"/>
    <dbReference type="KEGG" id="hau:Haur_5220"/>
    <dbReference type="HOGENOM" id="CLU_945849_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5119-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="294" mass="33665" checksum="E3BD27E84240D433" modified="2008-01-15" version="1">MAAPQRTREPSPAWQQLEMKLTCPKQHVYELIRPVVLFDQPVAERAAETATAERTLYRHVQTFRQHGLGATQRPATAPIRAAARLPAEAIAYLLAIKAEYPPMRHYELATICLVRFGRRPSIKTVKRALATNSLPMLTTRRFPPYHTIPDIVERRRAILRLITEGWTKKSIAGYLGISRKTVHGVLKRWDTEGLAGLKRRSSAPHRHGRRLASMVQHHVRRLQRNPLLGAWRLHAALRREGIHVSPRTCGRLMAINREVFPELRPPEPPPKKDPQPMPFAAQYRHQSPRGYPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N4</accession>
    <name>A9B8N4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07698">
        <property type="protein sequence ID" value="ABX07698"/>
        <property type="gene ID" value="Haur_5070"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5070"/>
    <dbReference type="HOGENOM" id="CLU_350831_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5132-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="692"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="802" mass="92203" checksum="4656BBCC940EAB4E" modified="2008-01-15" version="1">MQYRFINKIIIGIILSIIILAINIEFWKKSGVGFFVNPNNNKIMFIEKDLIEKGVDLKIDDRLIAIYNKKWEDVVNDWNFSRFEPNINEHIPITIDRNGSIIHLEIIKSAPSLDNQINKIVNIIISLCCIITGYKLSSKSFYEGIAPSGIGILWFGVGVVVGLHLFAGQGAVRLLITLEWIMITFLSPYFTIMHLFFPYRPESIFNIRKFENKGIYIFFTMNVFLLIFIWDYKENLLSIVAKLNIILPVFLLISFILSTLILFKAYKINNISHIRRQIRILISTYCMVICLWIVFLITPMYIFETPITSQINHIATILIPMSYMISGTAPDLYRFDKLFLIILSYIISFSIDIIFNITLFNILNKPIHENHIAASICIILLFHPILLLVRKYIPILKKENDYKYFNQAIIDLSKTLESDQLTRPIVTSLGKVFNNPSMGIYLRREIDDELLNCVYNDRMPNIPEKINLKDLNIFDDNADIMKILDFRNKIQRDISNNNNYASMLLYDPQITLLCPIYHPQYKLLGLIAVGRRNDLDPYRLQDIEELQKLINASSMAYGNSYLYTQKSIAERTVRELFSSLKNIQDITAKKIAREIHDEIINVNIKLNIETIQNLVGYIDDQFILDQLDLLLTGEKDTAYSLRMICESLHPSGIDDPLGFIPVLSNQIDQIRCIYKGIIDIVVINKIIPISTSIQHEIIRVVKEAVLNSIKHANATTITIEICYPNSNNSALRVIISDNGSPKQPVLNRPGHFGIRNMKERIYMIGGRIEIQSDINTGTRVSIFVPLNSGVSVEQPDLLGIYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q5</accession>
    <name>A9B8Q5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07719">
        <property type="protein sequence ID" value="ABX07719"/>
        <property type="gene ID" value="Haur_5091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5091"/>
    <dbReference type="HOGENOM" id="CLU_365936_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5153-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="581"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="642"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="762" mass="84591" checksum="C60BF074558915CA" modified="2008-01-15" version="1">MSAVSPLSSTPQHGWFEHLHLRRYSRTMLFDIMVLIACIMPGIMLSHQQLQEPWNAFRVARAQLSTNQGSVADYTTSAGAYRAEHVGSDLIHTALINATDWPLDGLVLAPIGALMLALAYYGIAILLSPSRRWAAGIALFSSWYYPGIYSQFGTQTYVWVYSLLIGFLIVFFQWLNHPKRSYEWLLTAIFLATFLHYHTTPLWMIGLMIIGTAASKRAQRTTSSSYRYSWLLPLSWLAWDITFESVLRNGWQQLQAVNTNTIGQSFLSKVFGPLLQRTPAGLDPFEIAPINPPLATWSTLLCLLILIVPVGWWMITQLHVARKTRDFHALIATPRHIFIWAIIGIAMAHTIMYLLYGALSFRVIPVLFPLLIPMIWRDAPWKSWSMGLLILLVGSAIVGFFSFAPTIQPDMTAAQTGRASRLLAKNSTILSDANLYGSLALQRAIDNQTINLAWIDAPLYRAMVDGQPLPTSIDAIAIAKTTKPLITSHWQYFAAWMVSNPMIEHHPSMNQVYASSVLSVLQPINHALPMTVPSDPPTKSLMWFVPALRLLGAILGLFLIPGLAIFWVAQRKQIFGADLDIRTILACTIALSVLNLTVMGYLVHLSGMNINGIVVLTMMLPVASLIALRLKGQRFMIAFRWWRYGISIVIVLGCWLGFATHGVLAQPTAMPALEVFATQATTGSLTIEVANNTDTATPATVVIETPEGSVLMTTQQVLPAHRVTDIPWVIPATAAHQPAVIRVITDQQPPLTLWFAQVPTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8R9</accession>
    <name>A9B8R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07733">
        <property type="protein sequence ID" value="ABX07733"/>
        <property type="gene ID" value="Haur_5105"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5105"/>
    <dbReference type="HOGENOM" id="CLU_1253548_0_0_0"/>
    <dbReference type="OMA" id="INGVHYG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5167-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="SSF159941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="25113" checksum="3AF0B1C1C26080E8" modified="2008-01-15" version="1">MPRRRPNPGICAWCGEVTTPSRVIAHLAGCAPYQAAIAAADERTSTRDTIYHLRAQDAQTPFFWLDLAVMGTARLHDLDHYLRAIWLECCGHLSQFSDGRRGPALAIERPIHTVFQPGSTLTHVYDFGTSSETTITCLGTRVGAALTPYPITRLMRNQPPDDRCTVCQQPAIWFCAWCVGADTAWEPRCDGHAAIYHDAADDDAEVIRAVNSPRVGMCGYNGPAEPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W4</accession>
    <name>A9B8W4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07778">
        <property type="protein sequence ID" value="ABX07778"/>
        <property type="gene ID" value="Haur_5150"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5150"/>
    <dbReference type="HOGENOM" id="CLU_034461_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5212-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03487">
        <property type="entry name" value="RT_Bac_retron_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000123">
        <property type="entry name" value="Reverse_transcriptase_msDNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00866">
        <property type="entry name" value="RNADNAPOLMS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="584" mass="67429" checksum="520FA446A7E759E9" modified="2008-01-15" version="1">MSLHLSSDPDTLRQQFFQLKSRDDLLNLLDISQQQLLYYLYICPENKRYRHLRLRKKRGGYRTIYAPATHLKIVQQKLSSILQLIYEQKPAVHGFVPHKSIVSNAAMHLNKTYVLNLDLQDFFPSINFGRVRGLFMNQPYYLNEEVATILAQICCHRNTLPQGAPTSPVISNMICAKLDRELLRFAQANRCVYTRYADDLTFSTNTRQPPSKLVRRTEATASIELGRDLVSIITANGFQVHPEKSRLQVKGRRQEVTGLTVNHFPNVPRRLIRQIRAMLHAWRKFGLDAAQQHYYAHYCHRQYPVFKPRPPFRQVLIGKIAFVGMVRGKHDQLYLRLRDQLLNLDPTYRAAVEKKAEETFILSTPLIKTEGKTDWKHIKHALRVLQAQGLYAGLSLDFDESLTEGGSSELKKTCYYLSRVKQAQIIIALFDRDEPNIIREVADGDRFKAWGNQVFSFVLPIPDHRTHTPDICIEFLYPDNNLLLVDEHGRRLYLSSEFHETSGRHKENPAISCLLSSKFKKDAKLSIIDASVFDANHRSIALAKDAFADYILHDQVPFNRMNLDGFKPIFDMIIAILRAETNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUH9</accession>
    <name>A9AUH9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0447"/>
    <dbReference type="EnsemblBacteria" id="ABX03098">
        <property type="protein sequence ID" value="ABX03098"/>
        <property type="gene ID" value="Haur_0447"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0447"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="RMGYKWN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-453-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="229" mass="25665" checksum="CDC6CDB21B3AEFE3" modified="2008-01-15" version="1">MSRILIVDDDPAILSGVSTLLEQAGYEIAQAASLAQARSHLQAFNPPSLVILDLMLPDGDGFELCRQIRQGGQYLPILMLSARDELQDRVEGLTVGADDYLTKPFAPAELVARVRAILRLAQHQRETIGSFECGKLRFDCELQRAWWDEQLLELTPKESGVLLQLMRQPSHVWGRLALLQTVWGTNFLGDSRIVDVCVQRLRAKINQLDANADPIQTVRGFGYRLKCEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUL0</accession>
    <name>A9AUL0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1894"/>
    <dbReference type="EnsemblBacteria" id="ABX04537">
        <property type="protein sequence ID" value="ABX04537"/>
        <property type="gene ID" value="Haur_1894"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1894"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061564_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1923-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="240"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="37725" checksum="E11A678260099EE8" modified="2008-01-15" version="1">MSQPTEQALVTKRLKTTVYWLLGGSLISMFLYMVLGDWIAVGSFAVTSGLLGTAYWLILRQHNQSAVVLMNMAALCLVIVGSFRFFTLLSIATVTIISIVLVLPFVDSRRLLGICGLAWVVSIISIANRLRIDQFPWAEMPIRVSLNSVSILVVMGLLWQIHRQLTNSLQASERSNQALRASQQSLEQQVEQRTAALQKALQEVQAQADSQAVLAQQLAEQQTTIRSLSVPILPITQHSLVVPLIGDLDAERLGTLVEQILTNLKSQRTRHLILDVTGVPTLDRDAGHSLLKVSNAARLLGAKTTLIGVRPDVAEMLVSIGLDLRSIGSEKDLQSVVYGLVRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM0</accession>
    <name>A9AUM0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="7" type="ordered locus">Haur_1904</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1904"/>
    <dbReference type="EnsemblBacteria" id="ABX04547">
        <property type="protein sequence ID" value="ABX04547"/>
        <property type="gene ID" value="Haur_1904"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1904"/>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_6_0_0"/>
    <dbReference type="OMA" id="YVFHPYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1933-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="242"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="37977" checksum="C3E7CCEB8D565DC7" modified="2008-01-15" version="1">MHDLEHQAAEPSLWDNPQQAQSILQRLARMQEELKMWDSLAVDLATLRDLLQLSADDADSLSQIEREVNGLTKSVDQLELSILLGEKYDSTNAFISIQSGAGGVESQDWAQMLLRMYSRWGESQGFRTTIVDMMDGEEAGIKSATLELRGPYAYGYAKAEAGIHRLVRLSPFDANHRRHTSFARVEVLPEVDDAAEVKINPEDLRVDVYRAGGHGGQGVNTTDSAVRLVYRGGTPDEIIVTCQNERSQLQNKETAMNVLRARLLERELARQVAERAKLKGEHRDAAWGNQIRSYVLDDRRVKDHRTNVETSNTQAVLDGEIDLFIDAFLRWRTEGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP2</accession>
    <name>A9AUP2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolysin A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TlyA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1926"/>
    <dbReference type="EnsemblBacteria" id="ABX04569">
        <property type="protein sequence ID" value="ABX04569"/>
        <property type="gene ID" value="Haur_1926"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1926"/>
    <dbReference type="eggNOG" id="COG1189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058015_3_0_0"/>
    <dbReference type="OMA" id="VLMVKPQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1955-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Haemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="PTHR32319:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="7"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="28574" checksum="98AC41222D84B047" modified="2008-01-15" version="1">MTKVKKHRLDVLLVELQLAPTRAKAQALIMAGEVIVNSQAETKAGTMIDPAAQITLKSSLPYVGRGGLKLAHALDSFNINPQGCVALDVGACTGGFSDVLLQRDAAHVYAIDVGYGQLDWKIRQDPRVTVLERTNIRYLEHLPHAEQQPAPLATCGVVDVSFISLGLVLPAMLRLLTADAWIVCLIKPQFEAGPEHVGKGGIVRDSAVHRQVIERVAQQANNLGLGLTGLTRSPITGAEGNIEFLGYFQRNAVATIALPQALIGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR4</accession>
    <name>A9AUR4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1948"/>
    <dbReference type="EnsemblBacteria" id="ABX04591">
        <property type="protein sequence ID" value="ABX04591"/>
        <property type="gene ID" value="Haur_1948"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1948"/>
    <dbReference type="HOGENOM" id="CLU_1530501_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1977-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="18910" checksum="B92D71C3B10B25A5" modified="2008-01-15" version="1">MKALRLFPKLVIAVGIIFALGGVGTIGAGIYINDFVGDKLAAQQITTPEDASIPNTPVTDIATALSMADIIQHHAAESGQGLSYAQMGRFALPDGAPVGTNNADEALKDANGKPVANSARNTQLTAAGLVTSLSLSAMAFGASYGAMALGLGFLVLGIIITGLGYALLGLITPEVAKRFGLQPVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV06</accession>
    <name>A9AV06_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3962</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3962"/>
    <dbReference type="EnsemblBacteria" id="ABX06594">
        <property type="protein sequence ID" value="ABX06594"/>
        <property type="gene ID" value="Haur_3962"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3962"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_4_0"/>
    <dbReference type="OMA" id="YCAANIF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4004-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1473"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1582" mass="169986" checksum="5518ABDBF4B44EFA" modified="2008-01-15" version="1">MIDRESQDFEFDTAVAIIGMAGRFPGANTLDQFWHNMTQGVQSIRFFSDEELLAAGVDPDLMSQPEYVKAGTVIDNIDSFDSAFFGFTPREAELMDPQLRLFLECSWEAFEDAAYSPETYQGLVGVFAGSAISTYMLNNIFNNAEVFRKAGMLQVGVLNSSDSLSTWVSYKLNFRGPSVVVQTFCSTSLVAVHMACQSLLNYECDMALAGGVAISVPHGTGYVYQEGGIVSPDGQCRTFDADGQGSVMSNGAGVVALKRLDQAVADGDHVYAVIRGSAVNNDGIRKVGYTAPGLEGQSSVIAEALAHAGVDPATVGYLEAHGTATALGDSIELAATIKAYKQQTDQTQYCALGSVKPNVGHLDRAAGVTGLIKTVLALKHREIPPSLNFEQASPEIDLPNSPFFVNTTLRPWETDGRTPRRAGVSSFGLGGTNAHVVLQETPLEAPSGRSYPQQLLLLSAKTDSALQTMAANLASFLRAHPEVDLADVAHTLQVGRTAFNHRRALVARDRDDAIAQLEAAGARGLTANQTDRDRPVAFLFPGVGDHYAGMAADLYTHEARFRAVVDECCTLLNPLLDQDLLAVLYPESGRGNGAPAAGLDFRQLLAGLPAGTPAGTLHQTELAQPAVFVVEYALVQLLASWGIRPQALLGYSLGEYVAATVAGVLSLEDALRLVALRARLIQNLPAGAMLAVSLGEDDARRYVRGDVALAAVNSPSASILAGPAAALEAVARQCAADEVACRWLETSHAFHSAMLEPARAALTDLTCSLTLNPPAIPYVSNVTGTWITVEEATDPGYWARHMCQTVRFAAGAGALLEGEPALILEVGPGQALASFVKQHSACSRERMGQILSALPASHGRQAELSHVLETLGRLWLAGVNIDWAAFSAGEQRRRLSLPTYPFERQRYWVDADAHGKSGSSLANDEFLNSADRIADVGDWFFVPSWKRTSPPSPILGAPLFADQHTWLLLVDDSGLGLVLAERLKQHGQTVVTIAPGAAFAAIDPASYTVRPAEREDYISVIKKLAREGIEPSRVLHLWLASPAESAGESPAEVDGILERGFYSLLALTQALGNQGVERCEVNVVTTGVHAVVGQEAVNATKSTVIGPCKIIPQEHPNLTARSIDVIWAPDRQGCEELVDRLVVELASTPTGVVIALRGQHRWVQAYEQIHLPEFSHPHARLRDQGVYVITGGLGGIGLALAEYLVASVRAKVVLIGRTALPSRERWDDIIAAEGTESGTGHRVHCIRQLEASGAEVLVLQADVADAGQIAAAIDQAVARFGAINGVFHAAGVPGVGLMQLKTAEAAASVLAPKVQGTLAIAQAVRSLPLDFLVLFSSVAAAAGGGQGQADYCAANIFLDSYAQLHHRDNGVTISIGWGEWHWDAWSEGLQGFTEEVRAFFIASRRTFGIDFADGMEALRRILAYDLPQIFVSPRDLTFLVEASQRSFAAFLKMREDREQSRYPRPALAVAYAAPRNDLETRIATIWSDVLGIDPIGIDDNFFDLGGNSLLGLDLFGRMRKALKLDNFPAYVLYESPTVELQAAHITNLQQPAIAHDDGDEHEDEQRRMQLNYFVDLDEMGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVG1</accession>
    <name>A9AVG1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2009"/>
    <dbReference type="EnsemblBacteria" id="ABX04652">
        <property type="protein sequence ID" value="ABX04652"/>
        <property type="gene ID" value="Haur_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2009"/>
    <dbReference type="eggNOG" id="ENOG5032YRU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192336_0_0_0"/>
    <dbReference type="OMA" id="HMELVGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2038-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025629">
        <property type="entry name" value="DUF4287"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14117">
        <property type="entry name" value="DUF4287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="73" mass="8219" checksum="DE22BDACACC9D4C9" modified="2008-01-15" version="1">MTQEKPPKGPASYFPSIEKTYGYPIDHWMTILDSMVGKTHMQMVAALKTEHNLGHGHANALVAYYRSQQEPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ6</accession>
    <name>A9AVQ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4024"/>
    <dbReference type="EnsemblBacteria" id="ABX06656">
        <property type="protein sequence ID" value="ABX06656"/>
        <property type="gene ID" value="Haur_4024"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4024"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019327_2_0_0"/>
    <dbReference type="OMA" id="GMQGAWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4066-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Amino_oxidase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="547" mass="59583" checksum="40AF8EA1BFB0C3CE" modified="2008-01-15" version="1">MAQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAHIMIHLTPVVRELELHKFGLEYIDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDAHAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFKGEKGTHPLDILRRLFTSYGHLINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAMAARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPEQLPNGLVERVGRIRVGNGFGMAVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLNRAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLWGQYHPYQLSNGEDWDSIAEREADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPELSEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGVVAWAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW9</accession>
    <name>A9AVW9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0559"/>
    <dbReference type="EnsemblBacteria" id="ABX03207">
        <property type="protein sequence ID" value="ABX03207"/>
        <property type="gene ID" value="Haur_0559"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0559"/>
    <dbReference type="eggNOG" id="ENOG502ZSEP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1330419_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-568-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="21276" checksum="E9536BEBBCE7577A" modified="2008-01-15" version="1">MAGVIGTVNQLTSPIWAGDFLDREHLMPGGAKVDASQFLATDGAIITLSANALVSATSISVTALANPIPANTMLRFGAGKYAYSTAAAAAGATSIAVEALPVALSSGDKATYNGSGTKPVTIVSGTLIGRTWAERDAGTAFGPAADADEEIYFLAFDISDATKNNDADLYRYNSIVKETFVPGWAGLSSTLKAFVRSHYQCTVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY9</accession>
    <name>A9AVY9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein, Crm2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0579"/>
    <dbReference type="EnsemblBacteria" id="ABX03227">
        <property type="protein sequence ID" value="ABX03227"/>
        <property type="gene ID" value="Haur_0579"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0579"/>
    <dbReference type="eggNOG" id="COG1353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012640_1_0_0"/>
    <dbReference type="OMA" id="YVAAIPW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-588-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038242">
        <property type="entry name" value="Cmr2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024615">
        <property type="entry name" value="CRISPR-assoc_Cmr2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013407">
        <property type="entry name" value="CRISPR-assoc_prot_Cmr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040942">
        <property type="entry name" value="Minimal_Cpol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12469">
        <property type="entry name" value="DUF3692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18182">
        <property type="entry name" value="mCpol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02577">
        <property type="entry name" value="cas_TM1794_Cmr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="344"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="628" mass="71194" checksum="DA3404F33434789C" modified="2008-01-15" version="1">MNRSLLLIALGPVQEFIEQARRTRDVWFGSWVLSHLAKKVAQTLPREGLIFPTGDSLPSPEAENSDPSTERISYSNQILVIVPDAQAAITHAKAAFDQEIDQFVNILLKTKQINWLEGLSEEQREQQLIKQLKDLFEFQYVYVDLPDDQHYAQQRKKLYQLYAARKNTRNFGLIDWQQDPQNMKRSDKSSLDGWHTLIANGAKSGENLSAVDLLKRMLKPQDLDQAYPKGLDGFPSTSHMAALAFAEHVNQSTLARQGWERYINNLRSTGYRITEYLPRVQRFDRIALFPSENTNRDFFDGSLVFESRLGEDFANTDLNTVIIKQARGYLEDFITAYAKQRPNPYYAIIAADGDKMGNLIDSISDVQIHRDLSKVVTTFAKDAAQILENDYQAAVIYAGGDDVLALLPLHTLLAATKKISDLFIEYMQPLAEQQAVSTPTLSVGVAIVHHLEALQDSIQLARKAEKLAKKPRNALAIILSKRNGSDKTIVGQWDTEFYQHLTKLVELHCQQTIPDGFIFELDELLKRFDFGLINDRTELQQTLKIIEHETLRILKRKQIQSAGEATFLAADVINLLQNIIGYCSSHSSNSDQADQYLRDFIAMNLVARELANVQALFEKTQPQGVPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW23</accession>
    <name>A9AW23_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_0613</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0613"/>
    <dbReference type="EnsemblBacteria" id="ABX03261">
        <property type="protein sequence ID" value="ABX03261"/>
        <property type="gene ID" value="Haur_0613"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0613"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037123_1_2_0"/>
    <dbReference type="OMA" id="IELHITF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-622-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="302"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX03261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="39349" checksum="5319BEE553B12499" modified="2008-01-15" version="1">MWSMRIGNVSGIPIKLHLSWLILAGLSIYSFEQMFTLNGQSGLPLALLGTLLLLCSIVLHEVGHALMARRLGLRVTAITLFLTGGLTELADDVDLPQSEFKIALVGPLVNVGLAIVAFVGAWFSQGVWASFWATLAIVNGLLAVFNLLPCHPLDGGRVLRSIFWFLNDDLLRGTLQASMVGRYLGNGLMIIGLVALFSNALTGSLLLLMGWMTNRAAVSNFVQTTLNYTLSRALVGEVMTRSFRTVSPHLTLDLFAGQYLLGQAEPAFPVVHSERLIGMISVQHLYRYAMGEWRSVSVGDAMTPKADLPRLNVGDSMQTAYYTMLGQRYDSLPVTDGDAVVGIVRHRDVVAFVQSALKINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW68</accession>
    <name>A9AW68_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2078"/>
    <dbReference type="EnsemblBacteria" id="ABX04718">
        <property type="protein sequence ID" value="ABX04718"/>
        <property type="gene ID" value="Haur_2078"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2078"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081790_0_1_0"/>
    <dbReference type="OMA" id="FRGWVAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2106-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="37"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23711" checksum="AE02E5FC8B4E2FDA" modified="2008-01-15" version="1">MIDEYSARARQSVAGRDASLLIGRALFENTLGAHAKILVVGAGWGDEIAALATANPGWQFVGVDVSEDMLRLARSRFATAPLPNTIALHHTDVRDLDDENFDAATCILTLHFIADDGAKLAMLQAIHQRLKPGGPFFVVDGIRDLDDAAFQEHVAAWKRHALNNGMPGEMVEPMVANTITLPLVSEQREVELLHEAGFGKIRKVYQGLHVNGWLAVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW80</accession>
    <name>A9AW80_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2090"/>
    <dbReference type="EnsemblBacteria" id="ABX04730">
        <property type="protein sequence ID" value="ABX04730"/>
        <property type="gene ID" value="Haur_2090"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2090"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_10_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2118-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="496"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1033"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1146" mass="127074" checksum="D3BFE3AE2203505D" modified="2008-01-15" version="1">MSYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGICLRRTPQLIVWMLAILKAGATYLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNTIEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPKGVLISHANALTFLAWAETTFSVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSAVQTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVERTASRPPAIGQPLTGTTCVILDAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLPNPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRGFRIELGEIEAQILRLAPLQAVVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGKLDRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKRIEQTWQLQLSITRLFEQPTLAAWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWFAEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEMLRSSIQLIAGIPQQTIMLKPVWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGVLWAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPLPALATDYPRSTHMQGLGISQTYQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQRSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQTWLDLLQQTRMVALQAYQHQALPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLLVQPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHYSNKLPTLQPMAAPPQTALEQTLADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQLLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATALQQIKTMSASTKQALQQKAAGRISQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA8</accession>
    <name>A9AWA8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2118"/>
    <dbReference type="EnsemblBacteria" id="ABX04758">
        <property type="protein sequence ID" value="ABX04758"/>
        <property type="gene ID" value="Haur_2118"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2118"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_3_0_0"/>
    <dbReference type="OMA" id="NQYKGLP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2146-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="39439" checksum="0E12E0530C748A12" modified="2008-01-15" version="1">MNYTVFFRRIRESRLFWVLTAWAVILGFNALFIPEFFRINIQDGHLYGNLIDVLNNGAPLMLVALGMTLVIATGGVDLSVGAVMAISAAMGAVLINPAPGDKLVSNEILTRNATNTPLAIIVLATLAAGTLCGLWNGLLVSRAKIQPLVATLILMVAGRGIAQLITNGQIITIYYTPYFWFGNGYILGLPVSIYIVTAVAIIAWVGVRKTPIGLFIEAVGINPKATYYSGISAKNVQLLAYTFSGFCSALAGLILSSYVHSADGNNNGLNYELDAILAVVMGGTMLSGGRFSLLASVLGAMVIWTFTLSMYTLGVPANALLAGRAVLVLLVILLYSDRRLVKRRSVRADTQPKSAVITPDENRDLPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC5</accession>
    <name>A9AWC5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">msrQ</name>
        <name evidence="9" type="ordered locus">Haur_2135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="7">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MsrQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2135"/>
    <dbReference type="EnsemblBacteria" id="ABX04775">
        <property type="protein sequence ID" value="ABX04775"/>
        <property type="gene ID" value="Haur_2135"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2135"/>
    <dbReference type="eggNOG" id="COG2717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080662_0_1_0"/>
    <dbReference type="OMA" id="LHFFWMR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2163-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="52"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="214" mass="24775" checksum="B99EF631BF0F2454" modified="2008-01-15" version="1">MVSQLKRHWLRYLVHVACLVPFGLLIFDYLTDQLTVNPIQAATLRTGKTALVILVLSLACTPIKIFTPFKQVTMLRRPLGLYAFFYVCLHLLIFVGWDYGFDWEFISEAIGEKRYMIVGLIAWLLLIPLAITSTKGWMRRLGKRWRLLHRLVYVIAGLVILHYVWLVKADVREPLAYGAAIGLLLLLRLPVLRRWLPKRQIQPANQPERPTETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWC9</accession>
    <name>A9AWC9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphotransferase (Aminonucleoside antibiotic resistance)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2139"/>
    <dbReference type="EnsemblBacteria" id="ABX04779">
        <property type="protein sequence ID" value="ABX04779"/>
        <property type="gene ID" value="Haur_2139"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2139"/>
    <dbReference type="eggNOG" id="COG0645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108932_1_0_0"/>
    <dbReference type="OMA" id="WLDTSRQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2167-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="182" mass="20395" checksum="BED67BB3195083E2" modified="2008-01-15" version="1">MASNAVIVVITGAPGSGKTTVAKHLAQRFDLSLHIPTDELRSWVVSGRVEPIPVLTPPAIEQLRLAREVVSTTAGLYQKHGYSVIVDDVLTSADLQAMFAQADQSQLHKILLCPVFERVIERNYERYRQFDQQKWQPVIANIYQDLCRHNTPDQGWIVLDTSNLNVTQTVDAILHPIRSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWE1</accession>
    <name>A9AWE1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2151"/>
    <dbReference type="EnsemblBacteria" id="ABX04791">
        <property type="protein sequence ID" value="ABX04791"/>
        <property type="gene ID" value="Haur_2151"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2151"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_908438_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2179-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005073">
        <property type="entry name" value="Peptidase_M74"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03411">
        <property type="entry name" value="Peptidase_M74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="50"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="100"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="32496" checksum="5C037F2C7525DC3E" modified="2008-01-15" version="1">MKALVWRIASFTLIFGITLGSIGSAQAFSAAFFHTISKGNRGTDVKAMQYLLNISADGVFGSGTESSVKSFQSSRGLGADGIVGPNTWNALIVTVRRGDNGNAVKAVQTLLNAKRNAGLTVDGAFGAGTESAVKSFQSHAGLSADGVVGPTTWKNLIWHYEYTDFSANICDQDPDGNGNANWGVASTVAQIEAAASDFAGYGKGKVPLGDISFEHGGDIPGHASHETGLDVDLWPIRTDSKQCTGSRITWQSSTYDRAATRNLVKAIRAAAPNQITVIYFNDPVLISEGLTTSYPNHDNHLHIRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG1</accession>
    <name>A9AWG1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Silent information regulator protein Sir2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4088"/>
    <dbReference type="EnsemblBacteria" id="ABX06720">
        <property type="protein sequence ID" value="ABX06720"/>
        <property type="gene ID" value="Haur_4088"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4088"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_0"/>
    <dbReference type="OMA" id="YRIEEIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4132-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="244" mass="27031" checksum="5B48EBBA051FA30A" modified="2008-01-15" version="1">MVLSLDLRRYRNIVVLTGAGISVASGVRPFRGPNGVWNEWDIERCATRTALEQSPQLVWQAFGPLRSQLQTTQPNAAHRALARFEQSLGKHQRFTLITQNIDGLHQLAGSRNLVEFHGSLRQSRCSDEQCDQPSFVDQRAHTQTLPLCPTCGKPLRPDIVLFEEAIPVWAETQAKRSLRECDFFLAVGTSGTVFPAAAFARTAQMLGARTMLVNLEPHAADDSAFEEQQIGRAEELLPTLLGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH9</accession>
    <name>A9AWH9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4106"/>
    <dbReference type="EnsemblBacteria" id="ABX06738">
        <property type="protein sequence ID" value="ABX06738"/>
        <property type="gene ID" value="Haur_4106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4106"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030724_0_0_0"/>
    <dbReference type="OMA" id="NERQDYF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4152-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045983">
        <property type="entry name" value="GUC-dom-containing_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19363">
        <property type="entry name" value="DUF5939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="433"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="612" mass="68035" checksum="46E54D6FC54C18B8" modified="2008-01-15" version="1">MALKPFRLKQSTIVPLGLAEVWEIAAQTSKVNHAVGLPPLVYSERTRSDGVREVVGNARQYGLPVQWVEHPFEWIYQKELRVERVFEHFPPLDRLIGGTILVPHTSISTEVETFVDVFPKNLLGYPVGWFVANQMITGQAAFFRSVAQKPNATNYFPPARKVRANRNVLQELRNRMRDLPCDQQLIDRLFELIQTQRDEDVATMRPFVLADAWGAERISLLRVFLYATWTGLLDMNWDVLCPNCRVAREPSPHLRDLTATAHCEVCNIRYDLNFDEYVELRFSVNPKVRSASNATFCALGSPALNEHIVAQARLKPNEQRELMVQLGPGGYRLRMLGIEQRCTIQAQAAGATNAIINLTATGPDQAALTLALEPTTLNVHNTTDREQLLIIEHDAWGVGRVSASLVSTLPEFRSLFSSEVLAPGLGLAIKNLTILFSDIKNSTPMYEQHGDSSAYAMVRDHFDVLFKAIEQHNGSIVKTIGDAVMAVFASPNDGVAAALAIHHNMQQANQARPERPPIVIKIGLHTGTCIAVNANEVLDYFGTTVNAAARAQGLSVGDDVVLTSDVMESAGVRAILSQHNLLSEPFTHNLKGISQVFTLYRLMPMAQREHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWX8</accession>
    <name>A9AWX8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0731"/>
    <dbReference type="EnsemblBacteria" id="ABX03379">
        <property type="protein sequence ID" value="ABX03379"/>
        <property type="gene ID" value="Haur_0731"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0731"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_11_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-743-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15194" checksum="5A9FF5797B17F151" modified="2008-01-15" version="1">MNRIHLNIPSDLVFERVVRASAAELGSTMGFPRERVEDLKLAVSEAVTNAIEHGGGGGVAGSVEVIFSLHADQLEVEIIDHGKGIEHFNTERRVVEEDNLEAGMLRGFGSYLISELVDQYEVQSSGTGTSLRLRIFKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY3</accession>
    <name>A9AWY3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0736"/>
    <dbReference type="EnsemblBacteria" id="ABX03384">
        <property type="protein sequence ID" value="ABX03384"/>
        <property type="gene ID" value="Haur_0736"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0736"/>
    <dbReference type="HOGENOM" id="CLU_2069880_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-748-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="13663" checksum="E8D41BC3F2D14958" modified="2008-01-15" version="1">MTRVDWFVFGFLAVFAVLVLFVFRKRWQGALGWLTLASAFVSGLVYTRNAEGLFGSVVIAVAAVIGVGLVGFDYYRFERPKRRARLEADDPLTPPSPFKIRRRPTLMQRRRFQREVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY6</accession>
    <name>A9AWY6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0739"/>
    <dbReference type="EnsemblBacteria" id="ABX03387">
        <property type="protein sequence ID" value="ABX03387"/>
        <property type="gene ID" value="Haur_0739"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0739"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075826_0_2_0"/>
    <dbReference type="OMA" id="FNWLMPY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-751-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20939" checksum="2554CF0401C3328B" modified="2008-01-15" version="1">MRVITGSAKGRQLKGPPDIGTRPMLDRVKESLFGILEGFNAFEGRALDLFAGTGSLGIECLSRGAEWADFVEARSHVAAVTKDNLKTTKLAERAKVWNVSVDKFLQIIDEKTKYAIILLDPPYAMEGIPDLVVRVAEHGILDPNGVLVLGHWPKLVMPPQLGPLSLLKHRRIGDSCFSIYELSPALPPQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB6</accession>
    <name>A9AXB6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4204"/>
    <dbReference type="EnsemblBacteria" id="ABX06836">
        <property type="protein sequence ID" value="ABX06836"/>
        <property type="gene ID" value="Haur_4204"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4204"/>
    <dbReference type="HOGENOM" id="CLU_1413432_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4251-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="192" mass="20888" checksum="64F0B045B9F85A40" modified="2008-01-15" version="1">MMLRRPSQQQLVAVLRATLPLLLAAFLGGLLALALQPDPPTQTIIQVVTPTVLKAAATEVLPAPAPTPLPATPTVIVFPEDTISLELVTLRRDLEFTVGSLHLLRATIRIQNARIAHHDLQTSNVEAQLDLAQADLDAAFPLVSDEVRAAIQGLNEQINYLRDDLAIRPETIDSRLADLTEQVLVLANRDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI4</accession>
    <name>A9AXI4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asp23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0750"/>
    <dbReference type="EnsemblBacteria" id="ABX03398">
        <property type="protein sequence ID" value="ABX03398"/>
        <property type="gene ID" value="Haur_0750"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0750"/>
    <dbReference type="eggNOG" id="COG1302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113198_4_4_0"/>
    <dbReference type="OMA" id="SADCYLI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-762-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005531">
        <property type="entry name" value="Asp23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34297">
        <property type="entry name" value="PTHR34297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03780">
        <property type="entry name" value="Asp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="116" mass="11898" checksum="D89894FB776C4B1B" modified="2008-01-15" version="1">MNQPFGTVTIAPDVLSAIVSLTAQDVAGVARLGSVPGQQRVGSMLGSGTANADGVAIRVVDDSVSADCYLIAQPDVNLLDLGARVQSAVTEALNEMVGMPVSAVNVYIQDVEQNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL1</accession>
    <name>A9AXL1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0777</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0777"/>
    <dbReference type="EnsemblBacteria" id="ABX03425">
        <property type="protein sequence ID" value="ABX03425"/>
        <property type="gene ID" value="Haur_0777"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0777"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_0"/>
    <dbReference type="OMA" id="VYYKPKY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-789-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="40643" checksum="79DE8B2A598BDBB2" modified="2008-01-15" version="1">MASITFDHVDKIFGDVHVLKDLNIDIPDQEFLVLVGPSGCGKSTALRCLAGLEEITGGQIMIGDRVVNNVAPKDRDIAMVFQSYALYPHMTVFDNMAFGLKLRKVPKPEIKRRVEEAAEMMAIGHLLDRKPRQLSGGQRQRVALGRAIVRDPAVFLMDEPLSNLDAKLRVQTRAEISKLHQRLKTTFIYVTHDQTEAMTMGSRIAVMRDGIMQQLDSPQTLYDHPVNKFVAGFIGSPSMNFIKGTLTKGDGRLFFDGGSFSVPIPNSRRAHIESHVGKEVELGVRPEDVHDAALLPPGINGDAVVETTVDVTEPMGSEIYAYLQSGQHSIIGRFDPRTSARPGQPIRAVYDMEKMHIFDIATEKALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXS7</accession>
    <name>A9AXS7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2253"/>
    <dbReference type="EnsemblBacteria" id="ABX04893">
        <property type="protein sequence ID" value="ABX04893"/>
        <property type="gene ID" value="Haur_2253"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2253"/>
    <dbReference type="eggNOG" id="ENOG502Z8AD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021406_1_1_0"/>
    <dbReference type="OMA" id="EAQHIVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2281-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025584">
        <property type="entry name" value="Cthe_2159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14262">
        <property type="entry name" value="Cthe_2159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734405" evidence="1">
        <location>
            <begin position="24"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="617" mass="61715" checksum="CEB2B3ACD3062C2B" modified="2008-01-15" version="1">MKPFTRALITSMLVAILAACANSQTTSNSNPTSSNSQAVVSATSATTTSPTVVVPTVESIDEALATKATPHDTSADLAWDTAELVEIKLSDSTITASSPNVKVEGTTVTISAAGTYQLSGSLSDGQIIVDTTDNDLVRLILNGVTIHSSTSAPIAIMQAEQVAVILADGSQNTLSDTIDASANATTEEDLPNATLYSKADLAIDGTGSLTIQANGNDGITGKDGLVINSGTIDISAVDDGLRGKDYLVVNGGTISINAQGDGLTADNEEDPTKGYISITGGTFTINAGGDGLSAVTDLLIDTGDLTISAGGGSSASVSADASAKGLKAGQNLVIADGTITIDAAEDALHSDSNVTINAGTINLAAGDDGVHADANLTINGGDLAISTSYEGLESAVITINDGAISLVAQDDGVNVAGGDGSSMQGGGMGRPNRNDSFAAGTYFLYINGGTLVVNAAGDGLDANGSIEMNGGLVLVHGPTEQMNGALDYDGGFALNGGILVATGSAGMAQAPDTSSTQASVLINYSSAQAAGNLVQILDQSGKAIVSFTPSKQYQTLVFSSPELQQGASYTINSGGSLQTHSASGLSSETANAGGTAYASFSVSDIVTQVGQRMGRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXW4</accession>
    <name>A9AXW4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2290"/>
    <dbReference type="EnsemblBacteria" id="ABX04930">
        <property type="protein sequence ID" value="ABX04930"/>
        <property type="gene ID" value="Haur_2290"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2290"/>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381197_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2318-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="726" mass="80254" checksum="1D41F972632FC1D3" modified="2008-01-15" version="1">MRSTIRLLIGLAIAGVLLLGSRLGVNAYQPARGLPIAGTWDTTFAQNLQQPATISSLTIDQNGDLYVLGDFHYVNGQAINGLTKWDGTTWETFNLEPDDINKIRAVTTYSDTLYIAGRFKTLQQQILNGVAAWNDTTFQALGSGLSGTLEEAAAEPIAYALHVYSDTLYIGGNFSFFNGGESYGIAQWNGAGIAQSVEFNSTVGSFISTPEGIIAAGEFWTVNFEPAQLARREYNRWTPINFGWPSMTLQAYTIHDTPYLVTRSRYAPYPSQLYRWQNSQRQLIGPTHPGAIDMLVGFDDTFYMQSGNKLWFLNQNQWVPAQLPFEISKLTALASDGETLYLAGDLTVDGQSRQLVAWDGSTTQSLGSFVGKQNVQSITGDFGQPMIATKPITVSNSGTIQRWNGSQWNTLAFGDTTISEAQLQTLGQRAYVLLNVPRALNSAAPASNIWHWENESWQSGVLSTTSSIKWHRSGQQLFTVLLPLQSNLPITGVVEFDGETLTQRLAINSLSPYEEQVFVHHNEFYLLIIAPWQWVDFLHIYKWDGIYWQSLPTQSLAKIDHYFAAWNNQLYMANTDGQLYRFDQAMQPIQIAQFDGPITTMQSLEGGGLYIGGDFMQVDGVTTGPIARFDGTTFRGLPSYPNGTVRKLAVDYNQLYIVGDFSKVGQVDSLGVAVFSFATPELTPTPTNTPTPTSTPTPTPTATISPTPAEISYRVYAPLTWAKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY07</accession>
    <name>A9AY07_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin--nitrite reductase</fullName>
            <ecNumber evidence="5">1.7.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.7.7.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2333"/>
    <dbReference type="EnsemblBacteria" id="ABX04973">
        <property type="protein sequence ID" value="ABX04973"/>
        <property type="gene ID" value="Haur_2333"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2333"/>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015667_2_3_0"/>
    <dbReference type="OMA" id="MGMTHGD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2361-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048307">
        <property type="term" value="F:ferredoxin-nitrite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="48"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="124"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="300"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="377"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="54371" checksum="C7D8A48713D831A5" modified="2008-01-15" version="1">MAVQIETIKKVKNGLDVLPDLYRYARLGFDAIPEDELERLKWYGLLHRKQTPGFFMQRLRIPNGILSTRQMRAIVSISRDFGRNTMDLTTRENIQLRWLRIEDVPEVFQRLQNVGLTSQQTGLDNYRNVMGCPLAGLHHAEIFNAAPIAQSVSLALLGREFSDLPRKFNITISGCSHDCAHSRANDIGMTPAAKEINGYRVLGFHVALGGALGGTSPQLGQDAGIFLTTEQALPFCRAVLTVFRDNGSREKRTEARLKWLIREWGMPRFMAEVEKVFGQAFFSAGESLLIEHSGDHLGIHQQQEAGFVTVGLLVPVGRTNAEQMVEIADLADAYGTGELRLTPDQNILIPNVHETCLERLLAEPLLQVLQPHAPGALRGLVSCTGRDYCHFALSDTKELSLQVATELASLIPAERRVDLKVSGCVHACGQHHVGEIGLQAQRLRLEDGTIVDAFDLFVGGNHQQLATLKARKIPVDQLAGRIAAELAVMDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY10</accession>
    <name>A9AY10_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NO3-/NO2-ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CmpA/NrtA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2336"/>
    <dbReference type="EnsemblBacteria" id="ABX04976">
        <property type="protein sequence ID" value="ABX04976"/>
        <property type="gene ID" value="Haur_2336"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2336"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037398_3_0_0"/>
    <dbReference type="OMA" id="GPKKDMA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2364-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734414" evidence="2">
        <location>
            <begin position="29"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="407" mass="43930" checksum="A88BF2978D6E5A19" modified="2008-01-15" version="1">MSKISRRNFLKTAASLGAAVAMPSFLTACGGSESASETGERPIKIGFIPLTDCASVVMAHTLGLYQKYGVNVEVVKEASWANVRDKLLTGDLDAAHCLFGMPFSVYTGVGGKAESELKIAMILNQNGQGITLSSALAKEVGYGDPSKLKALISQRPADKPATFAGTFPGGTHDIWLRYWLAAAGVDQNSVKIITIPPPQMVANMRIGEMDGFCVGEPWNGVAVKEGIGETVLATQDLWAGHPEKALVVNPSFAEKRRDDLKKIMKAILEASKWLDDFNNRSEAAKVIGGQAYVNAPADVIEARLKGQYNLGATLGERTFEPSKSMVFYQDGAVNAPQRSHAIWFMAQYVRFGLLPSAPDYTAIADKLIMRDLYAEVAKEMSLTVAGDDLQPFTVTLDQQTFDPKSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY90</accession>
    <name>A9AY90_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4340"/>
    <dbReference type="EnsemblBacteria" id="ABX06972">
        <property type="protein sequence ID" value="ABX06972"/>
        <property type="gene ID" value="Haur_4340"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4340"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_3_0"/>
    <dbReference type="OMA" id="YTDGWLP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4393-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735103" evidence="1">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="47"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="374" mass="39035" checksum="8E18F27260CB12DC" modified="2008-01-15" version="1">MNVRRSAFTSLLLILISSVIAACGSESATTAPTTGTGGTTSSGGKVVALFLPDAKTARYETADRPYFEAKMKELCPDCQVIYNNANQDASLQLQQAEAALTNGAKVLVLDPVDSAAAASIADKAKAQNVPVIAYDRLILNSDGVSYYISFDNESVGKLQAESLVAQLDKQGIANPTIVMINGSPTDNNAKLFKAGAHSVFDPLVSAGKLTIANEYDTPDWSPDKAQDQMQQALTSMGNKVDGVYAANDGTGGGAIAAMKAGGLSPLPPVTGQDAELAAIQRILAGDQYMTVYKAIKPQAEAAAELAFALLEGKTSDKATSKVNNGKIDVPSILLTPIAVTKENVKDTIVKDQFHKVDQICAGDFAKACADAGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYG4</accession>
    <name>A9AYG4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0898"/>
    <dbReference type="EnsemblBacteria" id="ABX03546">
        <property type="protein sequence ID" value="ABX03546"/>
        <property type="gene ID" value="Haur_0898"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0898"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741544_0_0_0"/>
    <dbReference type="OMA" id="KVCVACR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-912-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="182"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="48416" checksum="DDAEE4EC83624C05" modified="2008-01-15" version="1">MSLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVLPAPRRIQLEGEKISLRALEQMVHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQLAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIACGNPLVANAEKVQPMSQTLRYTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIVNHLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAWIGSVGDSRVYLFNRKGVSEHTQQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRSVGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRDAVFEASSPQACCGSLIAIANSRGARDNVTVVLLSAEERTDQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYJ3</accession>
    <name>A9AYJ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-acetylhomoserine/O-acetylserine sulfhydrylase</fullName>
            <ecNumber evidence="5">2.5.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0927"/>
    <dbReference type="EnsemblBacteria" id="ABX03575">
        <property type="protein sequence ID" value="ABX03575"/>
        <property type="gene ID" value="Haur_0927"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0927"/>
    <dbReference type="eggNOG" id="COG2873">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_4_0_0"/>
    <dbReference type="OMA" id="TYTLFAH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-941-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="426" mass="46048" checksum="7F11DA4ECCC980E7" modified="2008-01-15" version="1">MADEVKFNRFETLALHGGQKPDPTTGSRAVPIYQTTSYAFRDTDHAAALFSLAEPGNIYTRIMNPTNDVFEQRLALLEGGIGALALASGQAAETFAILNVAEAGDNIVSATNLYGGTYNLFHHTLPRWGVQTRFVDASDPENFRAAVDERTKAFYLESIGNPKLQIPDFEKIAQIAHEVGVPLIVDNTAATPFLLRPIEHGADIVVHSATKFIGGHGTTIGGVIVDAGKFDWAASGRFTQYTTPDQSYHGLRFADLGAPAYILKARVQLLRDFGSCLSPFNSFLLLQGLETLHLRLERHVQNAAAVAKFLTEHKNVAWVNYPGLPGHPSYELAQKYLPKGAGALVGFGLKGGLAAGRSFIDKLQLFSHLANIGDSKSLAIHPATTTHQQLTDEERLATGVTADYVRLSVGTEAIDDILADLEQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYK5</accession>
    <name>A9AYK5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2343"/>
    <dbReference type="EnsemblBacteria" id="ABX04983">
        <property type="protein sequence ID" value="ABX04983"/>
        <property type="gene ID" value="Haur_2343"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2343"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_0"/>
    <dbReference type="OMA" id="WGGDTRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2371-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="12"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="136"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="136"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="28510" checksum="EFE8F6FADF9D8CB4" modified="2008-01-15" version="1">MDTFNVELRDKLILVVDDEPRLVTFMRVNLEAEGCRVISAENGRKALEKVREDMPDAVLLDIMMPGLDGYETLRRLREFSSIPVIFLTAKDEEDDRIRGLELGADDYIGKPFSHRELVSRLRAVLRRHYVTPTQAVSTTKIDDRLTVDFDRREVLVNGERISLRPTEYRLLYHLVQNAGFVMPHETLLAKVWGPEYRDESHYLRLYVTYLRQKIEEDPANPHYILTERGVGYRFVDFKKKHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYQ8</accession>
    <name>A9AYQ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2396</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2396"/>
    <dbReference type="EnsemblBacteria" id="ABX05036">
        <property type="protein sequence ID" value="ABX05036"/>
        <property type="gene ID" value="Haur_2396"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2396"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_0"/>
    <dbReference type="OMA" id="AKDYPLM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2424-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="99"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36219" checksum="33ABAF136F02E5AC" modified="2008-01-15" version="1">MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLSDAPLLEQYFNYLRSLSRGEFGISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVLGIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLAFQAGWFPLRHAYSDALSVDWGSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMFSYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLMITFAVLGANLLVDILYVWLDPRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ58</accession>
    <name>A9AZ58_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0956"/>
    <dbReference type="EnsemblBacteria" id="ABX03604">
        <property type="protein sequence ID" value="ABX03604"/>
        <property type="gene ID" value="Haur_0956"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0956"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028676_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-970-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="434" mass="47560" checksum="437F966E6982A887" modified="2008-01-15" version="1">MHTQKPVVVIGGGLAGLTAANYLARAGKQVIILERAKHLGGRARTNREHGFEINFGPHALYLKGAGARVLRELNVLPFGSKPIAPDVLLAEQQLYPTKSIKAALSTSLLNRRAKWQFLRSFAKLPFTNPTHYADRSFAQWIAQQADEPRARQLLAMFGRLTTYGAANDLQSAAATLENIKTGLAGVLYVDHGWQVIVESLINKARQTGVELRTSQRVQAIQPSHAGVTIQLADGTNIQAEAVVLAVTPQAANELIGTSQHFQRHYQRLLPITAACLDVGLRQLPQPQRRFLLGVDRPYYAVAHSSYAKLATQGQALIHVMKYLDPRQTYDPKQTRAELEQLLDQYQAGWRDQLVTNQFLPSITVSYDTPQVQFGGLAGRTPVVLNDCPNVYLAGDWVGIEGQLADASFASGYTAAKQLLQPATQSQMRSVGALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ63</accession>
    <name>A9AZ63_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0961"/>
    <dbReference type="EnsemblBacteria" id="ABX03609">
        <property type="protein sequence ID" value="ABX03609"/>
        <property type="gene ID" value="Haur_0961"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0961"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735235_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-975-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="376" mass="44077" checksum="B4E3477C0A20D4E8" modified="2008-01-15" version="1">MHWSGWIILLVVTLIGGWWFYQQYRHLRIEEQTRYAALEPDPDRVMRENLDYTVGDTHILFIFAQQNQAIKLIQAQKYAEAEAIYQRIMHYYQKFDPANQANFLVALQHYAVMLLEQGEISKAEQHLRDILAKQTALLGADHDNTLSTIQSLAQCMTASERYAEAETYYRQIIHSFDDLTSADDLKGEVLFFSLIDFANFLIERKSSEALLQYQRLQELQKIYFADQTKFEYYLKERLAFTQYAVMDNPELAIEQYRNLLDEIISKYGKNNKYYLRVGHFFAVVLDETEQHAEACQLLEQMYPHLTEHYPTDDPFVYHVAFNYITSLSHNQQPEPALAITDQLLEQLEAQESTSPWLEHFQALRQQLLDQKAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH0</accession>
    <name>A9AZH0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRISPR system Cms protein Csm2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CRISPR type III A-associated protein Csm2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This subunit may be involved in monitoring complementarity of crRNA and target RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated Csm2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2476"/>
    <dbReference type="EnsemblBacteria" id="ABX05114">
        <property type="protein sequence ID" value="ABX05114"/>
        <property type="gene ID" value="Haur_2476"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2476"/>
    <dbReference type="eggNOG" id="COG1421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131491_2_2_0"/>
    <dbReference type="OMA" id="VAYHKYF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2504-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010149">
        <property type="entry name" value="CRISPR-assoc_prot_Csm2_III-A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03750">
        <property type="entry name" value="Csm2_III-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01870">
        <property type="entry name" value="cas_TM1810_Csm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="144" mass="16504" checksum="F4D8CA99DE114656" modified="2008-01-15" version="1">MPEISEQEREAIIAGDDVEKLVEAAQKIGEKLARNRLTTSQIRGIFGTVRRIEMDWVMPSLQQQRAEAVRRAQREFALLQPRLAYQAKRERGGAVQALSDELTPAIKLVLKAKADKPDIFYQRFRNFVDFFEAILAYHRAFGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH3</accession>
    <name>A9AZH3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRISPR system Cms protein Csm5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CRISPR type III A-associated protein Csm5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2479</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This subunit might be involved in maturation of a crRNA intermediate to its mature form.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated Csm5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2479"/>
    <dbReference type="EnsemblBacteria" id="ABX05117">
        <property type="protein sequence ID" value="ABX05117"/>
        <property type="gene ID" value="Haur_2479"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2479"/>
    <dbReference type="eggNOG" id="COG1332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036878_3_0_0"/>
    <dbReference type="OMA" id="TPVHIGS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2507-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010173">
        <property type="entry name" value="CRISPR-assoc_Csm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38007">
        <property type="entry name" value="PTHR38007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01899">
        <property type="entry name" value="cas_TM1807_csm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="362" mass="41548" checksum="C43CD48F5F853A34" modified="2008-01-15" version="1">MTNYGLTIETLSPVHIGAGGPDLRRNIDFAIFNNVLYLLNVDAVLEQILPENPNDRLYQQILNTPDLGSFLTADLLSKHPELYYYKLEGVSKLETMRPVIKHWTHAPYIPGSSLKGALRSAWVRQHYQQRNLILDLQQLSDRREWAFQAQEARLLSPKASRPSQNPNYDLFRAIQVSDSQPAPADALRLYNAVVFPAANQGIPLDLEAIKPRVALQARIKFDDYILDKQAKQFGVREQGFSVEALKQAWREQGLARIQQELTFWTGRREGEHLQQFFSNLAQQANTAPDNCFYIDIGWGTGWKSKTLGDIIKTPQLAQLMRRYRLSRKEYREGDRFPKTRRAARDTKGALRVPFGWVKVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN2</accession>
    <name>A9AZN2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4454"/>
    <dbReference type="EnsemblBacteria" id="ABX07086">
        <property type="protein sequence ID" value="ABX07086"/>
        <property type="gene ID" value="Haur_4454"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4454"/>
    <dbReference type="HOGENOM" id="CLU_1145967_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4509-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="242" mass="27899" checksum="9B40215A00516BA9" modified="2008-01-15" version="1">MQWYDCGYLVMTRIQRPSDLDPLLFPETMYALRDCSFNALPEHWWRYFSADPSNLLAKELADWYTKNEAGLLLPNLFTTIELAQEFAQKLSNWPEELQIVRIGLAAAYHEQFMAEQTAKRPSEQPEGFLTMLQQPKQLPIQQGQWLGVELGWFNYSSIHSWVCESEHQRLIQHDAPVDCRPNQFGLLKSLAAAEYLIPQISIYNGINDDTPAPNVYPFCLIAYEPSLMNTKLHMPNLATSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN4</accession>
    <name>A9AZN4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4456"/>
    <dbReference type="EnsemblBacteria" id="ABX07088">
        <property type="protein sequence ID" value="ABX07088"/>
        <property type="gene ID" value="Haur_4456"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4456"/>
    <dbReference type="HOGENOM" id="CLU_1693100_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4511-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17961" checksum="074FEE993815C398" modified="2008-01-15" version="1">MGQLLDGAAFLSQTNAMQATLRQLIGGALWFHGPSCDLESFVIRVGEPRTREIQYYQLTINCAWRLRQQQQILLSSEDWLYDDDNNIEFEPSVAKFWAKHDPASLIIWSIEVKPQSGDLCFSINYDYKLDILINAAAGQHWVLHRDGLEIWRYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZR7</accession>
    <name>A9AZR7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4489"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07121">
        <property type="protein sequence ID" value="ABX07121"/>
        <property type="gene ID" value="Haur_4489"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4489"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_2_0"/>
    <dbReference type="OMA" id="FVFDQHD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4544-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="207"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="417" mass="46844" checksum="99CFD93C60DD5CA3" modified="2008-01-15" version="1">MGYTILSIASTSFFADYGAHVRIWEETRALQKLGHRIVIATYHNGDNMPGFEIRRSWDVPWVKRTMVGASHHKMYLDVALSWRALRVAMEIKPDLIHAHIHESALIGSVLSRMFKIPLVFDYQGSLTAEMLDHGFLKRDGMFYKPFHWLEDKINRTADAVLTSSFNAANMLRDDWKFPAERLYTVPDSVNTDRFKPFDGSAEWHAERERIRSELGIPAGRKIVAYLGLLAAYQGTNVLLEAAQIIRQQRDDVHFLIMGYPDVRSYLALAESLGVADIVTMPGRILYKDAHAYLALGDVAVAPKMSATEGAGKIPNYMAVGLPVITFDTPVSHEILGDAGVYAKFGDAQSLADEILGLIDNPERRHNLAQTVRTRAVNEHSWELAARQIEAIYERVLAKRAGNPLPEFPTSLQREQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B027</accession>
    <name>A9B027_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1086"/>
    <dbReference type="EnsemblBacteria" id="ABX03734">
        <property type="protein sequence ID" value="ABX03734"/>
        <property type="gene ID" value="Haur_1086"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1086"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1106-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="280" mass="30894" checksum="B050452418DA8724" modified="2008-01-15" version="1">MPSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRSYQAEISDFTQLRAALQTIKQQETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYIIAMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQSFKKLFGPYATSKLALSLWNQALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQQQFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B043</accession>
    <name>A9B043_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1102"/>
    <dbReference type="EnsemblBacteria" id="ABX03750">
        <property type="protein sequence ID" value="ABX03750"/>
        <property type="gene ID" value="Haur_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1102"/>
    <dbReference type="HOGENOM" id="CLU_996667_0_0_0"/>
    <dbReference type="OMA" id="IGSEYSW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1122-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="30668" checksum="110ECDD447FFB158" modified="2008-01-15" version="1">MWNLFRAEWTKTYKRPANIGLLLITLAIILITFVAQTGIALYNGKEDTGWTAAQFAMMFPNGFLFPSIILSAIGSMLAVVFMGNSIGSEYSRDTWKVLLPRRARRSDFIIVKIAICLLFMICLIIISLIFGQLMGLIGTAILGGTLFDFDSFSLGTLLKSLIPVLLQLVVFSSITLLVTMAGRSTIMGIVFGIVGNTIFNLAMSFSTLAAKILPNAHISNLEANWLYTGEEQTMMFEGVDRVFGTHISLSTSLMVVAAYIFGSIMLGILLFQRRDMAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B070</accession>
    <name>A9B070_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2541"/>
    <dbReference type="EnsemblBacteria" id="ABX05179">
        <property type="protein sequence ID" value="ABX05179"/>
        <property type="gene ID" value="Haur_2541"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2541"/>
    <dbReference type="HOGENOM" id="CLU_820782_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2569-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="338" mass="40478" checksum="8B6640CEE4F01937" modified="2008-01-15" version="1">MNSINIIFSGSIIIMLVILTFEIRKYGIVYLKNKEVREENKKIRLELNSLNEKYHELIMINNELVLDNNQLTLHKNEIINSKKANILSDKKINKYELEYQMLIELYNQMNIEFNKKNVLIEKLRAKMILFDLFIEINNKYRKYHGNESDNRKMISNYIYKLFFDIEQGLSKYYNEKIKLRTTILFPKIENLDLLKEYLRVYAYFEIGNVSIYDVEFYIGEDLEKRKEKSGVAGIAYIEKRVVYAQFSMSNDKPIKKNPDAQHHIFLPIEQEEKGILEYLMIYAQYINVSDKLNGVICIDSMKNDLFDDKNLVRYFNEFVFYNIEQFLGRYADDIMNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U2</accession>
    <name>A9B0U2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1164"/>
    <dbReference type="EnsemblBacteria" id="ABX03812">
        <property type="protein sequence ID" value="ABX03812"/>
        <property type="gene ID" value="Haur_1164"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1164"/>
    <dbReference type="HOGENOM" id="CLU_164819_1_0_0"/>
    <dbReference type="OMA" id="KMFHYRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1186-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="10589" checksum="532E0FA0F3E1044C" modified="2008-01-15" version="1">MSEQIDPELEELETEPAPRKTNAVEDEAFDYSVSKAGKVFISWYGKQVLILSGAKAQHFLANIANLDGEAAQLVMAKITGNFKRGNERLAKQKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K4</accession>
    <name>A9B1K4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1241"/>
    <dbReference type="EnsemblBacteria" id="ABX03889">
        <property type="protein sequence ID" value="ABX03889"/>
        <property type="gene ID" value="Haur_1241"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1241"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011856_0_4_0"/>
    <dbReference type="OMA" id="NSNAPYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1263-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="466" mass="50323" checksum="E9D28989F2D6F65F" modified="2008-01-15" version="1">MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEHFLARYSDTLTGSTGPRYWGFVTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAISMLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLNHDVARMGLYGLAPIPVLSGAPHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNSVDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVPYDSAMQFTRHSALQVEVFHNSAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSAGYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFTLAGNPDSTTIQAYLDAVRASGAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S0</accession>
    <name>A9B1S0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2724"/>
    <dbReference type="EnsemblBacteria" id="ABX05362">
        <property type="protein sequence ID" value="ABX05362"/>
        <property type="gene ID" value="Haur_2724"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2724"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_4_0"/>
    <dbReference type="OMA" id="PCKRAIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2755-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="49"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20906" checksum="51C255C34CA5D44D" modified="2008-01-15" version="1">MTSESETSAKQGLSRKEWLWLGAGIVVAIIVIATVAILTSGGSKPQTVVGIDRPVPDMVLKTVDGGSFNPTEYKGKPIIINFWASWCEPCKEEMPALVRTAERYGDKIAVVGINLTDQDNDQEIRRFIQRYAVTYPIALDNERVAQQAFGIFNIPVTFFIDSEGIIRYTRINAITESEMDHVLSELLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W2</accession>
    <name>A9B1W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2766"/>
    <dbReference type="EnsemblBacteria" id="ABX05404">
        <property type="protein sequence ID" value="ABX05404"/>
        <property type="gene ID" value="Haur_2766"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2766"/>
    <dbReference type="eggNOG" id="COG3956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094174_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2797-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29940" checksum="54E18114C6AF473D" modified="2008-01-15" version="1">MSNQRSMVSAVKQGSLTIVGTGITMIAHLTNEAHAWISKADQTFYLVMHPLADEWIHKLNPQAESLAHFYQADQPREQVYAAMVEHIWAAVRQGLRVCVAFYGHPSVFVTPTSDLVQRGQREGLRVNILPGISAEACLFADLAIDPGLHGYQSYEASDFLVRPRRFDPSTPLVLWQIGVIGYFKVVHDQLDSRAGLARLVAHLQAFYPARHEVTIYQAAILPIEEPTIQRVLLKDLAEQQVSAYATLYIPAYGDAQLDQSLAREFGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z2</accession>
    <name>A9B1Z2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="7" type="ordered locus">Haur_2796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2796"/>
    <dbReference type="EnsemblBacteria" id="ABX05434">
        <property type="protein sequence ID" value="ABX05434"/>
        <property type="gene ID" value="Haur_2796"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2796"/>
    <dbReference type="eggNOG" id="COG0216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_0_1_0"/>
    <dbReference type="OMA" id="ISDHRVG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="365" mass="41181" checksum="ACE981C41F777239" modified="2008-01-15" version="1">MEPEILARLARVEARYIELNDEMTQPDALSDHVRLTTLAREQTELGELVGRYREFMQAEKSVEEAKALLREENDPELREMAQLEIDELSARMEAIGAEVRVLLLPRDPNDEKNVIIEIRQGEGGDEAALFGADVYRMYQRYAEIRGWKTEVMSLSENGIGGFKEVIFEVQGQGAWSRLKYEGGVHRVQRVPATEARGRIHTSTITVAVLPEVEETAVEIKQEDYRIDVYRSGGHGGQGVNTTDSAVRIVYKAGTPEEIVVVCQDTRSQIKNRESALNVLRARLYAREQEKRQKELGESRLAQVGSGERAEKMRTYNYPQDRITDHRIGQNISNLPVVLDGALDRLIDALVTFDNAERLKALGMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B269</accession>
    <name>A9B269_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4788"/>
    <dbReference type="EnsemblBacteria" id="ABX07419">
        <property type="protein sequence ID" value="ABX07419"/>
        <property type="gene ID" value="Haur_4788"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4788"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2167479_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4846-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="110" mass="12496" checksum="49A52A0A72015D32" modified="2008-01-15" version="1">MSMTMDAAIDALFDHLAKQTPPEFFAEILDDVGWLIDDPTMDLHRTLRGWLIGDELEKVKVALSMQSMALLESDAERHAIAEQLVGRWPELEPLCRSSPQLRTTTLPNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E0</accession>
    <name>A9B2E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1340"/>
    <dbReference type="EnsemblBacteria" id="ABX03985">
        <property type="protein sequence ID" value="ABX03985"/>
        <property type="gene ID" value="Haur_1340"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1340"/>
    <dbReference type="eggNOG" id="COG5412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1989554_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1361-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="125" mass="13308" checksum="25D5DBBBDC248D55" modified="2008-01-15" version="1">MEHARDDGQALSNRDRQQSQVNHSEAGSPGISNIPRGAEVFTAEETKGMAARMVVPQGGMVGTMANALPTNQPSAPSIINQITIDARQATNPAAIKAAVEEVWNKKMKDILGSATIRLKTNPFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E3</accession>
    <name>A9B2E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1343"/>
    <dbReference type="EnsemblBacteria" id="ABX03988">
        <property type="protein sequence ID" value="ABX03988"/>
        <property type="gene ID" value="Haur_1343"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1343"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_8_0"/>
    <dbReference type="OMA" id="LVITDYM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1364-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13345" checksum="771E597FB51D2B6F" modified="2008-01-15" version="1">MTTHILVVDDEPSIRELFEDVLGDEGYVVHTVATGHQALAVYQTMPLDLIFIDIMMPEMDGITLCRRITTIPGMTQPPIILMSGGTTVTTIDGPYQAFLAKPFDLTNLLQLIHTLLSSEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G8</accession>
    <name>A9B2G8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1368"/>
    <dbReference type="EnsemblBacteria" id="ABX04013">
        <property type="protein sequence ID" value="ABX04013"/>
        <property type="gene ID" value="Haur_1368"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1368"/>
    <dbReference type="HOGENOM" id="CLU_596866_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1389-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="458" mass="48618" checksum="8AA72BEE711BB0CB" modified="2008-01-15" version="1">MTTMQLLRNGSVVIDFMPAGVNPTEGTTCYWLVDGSWQPQVPQRDRRLISNGEQFQPSVQSFAVNIFGGTNEDQAWAAYHALMVLLDDAERFYEEGYSSAVVWRTKPSDTTVHSDMLVMGRAGDTPMVGTSPTLIQDNDVWWILNVPVTFLCRPLRCAASSVSSSTSASANIATIHQPNFSGSAAPLESPTNLTLNVAAATNGATISGLIAVAPRGKMVKSAAWLFAPSPSVFGWSRQIQASGVYATDNLVCFYNFPSVTPSYSPNGVLTDIGPLNSRSVIQWAMLKTTAPFLITPVVRSNGALIEGRATLVDSATPIIVPLGQTSAPYLITGHQLKLTNLTNAGAIYINAILTIAADAGGWSVIPFASLPLPSTTTTITVDARYLSNPDASLTYTSAGVTQAVPTDSNPLALTKDLQLDVNLFAVNGNAWSATTENAASARTMTVQASRLNGAIIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2R2</accession>
    <name>A9B2R2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2875"/>
    <dbReference type="EnsemblBacteria" id="ABX05513">
        <property type="protein sequence ID" value="ABX05513"/>
        <property type="gene ID" value="Haur_2875"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2875"/>
    <dbReference type="eggNOG" id="ENOG5033XBV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1487124_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2906-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20405" checksum="140220AB421D3D85" modified="2008-01-15" version="1">MALFNHQLAEQITALVLQRYRSLGQALGATTLAEEAAAETAFQHNLNLLIEVANGRHMRSEIMLRRIELALEQLLDLLLGNALQSKAVFPEDFWQSEIGILVSRTRWWISAEDLITISNAAALAFGQNNQANRMRISRAIDNGLLDWVPDPSVANPQQNRRVLRSQVERLRDLSRLPELGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2S1</accession>
    <name>A9B2S1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2884"/>
    <dbReference type="EnsemblBacteria" id="ABX05522">
        <property type="protein sequence ID" value="ABX05522"/>
        <property type="gene ID" value="Haur_2884"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2884"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_4_0"/>
    <dbReference type="OMA" id="YYQIARS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2915-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23920" checksum="45162034A00EBD68" modified="2008-01-15" version="1">MSVDVEVLRQFTRFAALDPLALRDLARAMEVRSFRPGQYLVLEDDPRFGLFGILEGRVRLSRTASDGREQVLSIAETGELFNIEPFVDAGPAPATARAMAPTRCVHLPTAALPDVLRSHPEFTLILLRDLAAQARDLAVLLEDLAFRTVRARLARILLHEAADGTAALTHQELAARAGTVREIIGRTLRQMSDEGLVELARGHVLVLDMQGLAALIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V6</accession>
    <name>A9B2V6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cellulase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3383</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3383"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06019">
        <property type="protein sequence ID" value="ABX06019"/>
        <property type="gene ID" value="Haur_3383"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3383"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_467623_0_0_0"/>
    <dbReference type="OMA" id="MWITEFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3420-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731836" description="Cellulase domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="261"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="586" mass="67387" checksum="C6256B86E0EE0234" modified="2008-01-15" version="1">MRRRWVRLGLLMLIAMGVVLPGTKAEATPPPPLAQYFPETGQSAVNYFWQFWKNTPNAMRVLGYPISLPFVQESFTEPGKFYLVQYFERAILEEHPENFNHPTNGNKYFVLGRLLGKELAKGRENEPAFKPVANPNNGTVWFPETQHTLTNTPGPFLTFWRNYGGLSVFGYPLSEPFQELNPDTGKVYWVQYFERNRFEYHPEEKPEFQVLLGLLGKQYYNEHKTEPKLAVKEWFFRYHTRAEAIPVDFIYGYNVQAFYQERDRLYQLVNNAAFGWIRQQAPWEDLQAADGTIYWGELDKVINDAHAKGIKVLLSVVRSPEWASENGTHGLPSRRNFPKFGDFMQRMAQRYKGKVQAYEIWNEQNYAIENGGVVAPAAYYVDMLEYAYKGVKAADPEAIVVSGSPTPTATNRTDIAVDELIYFAQMFAIPKFWNNVDVIGAHFGGTYNPPDTKWPDNPGPGPGWRDNSEFYWRRIEDVRQVLVNSGNGDRQIWVTEIGWATANTSPGFEYGNSNTIEEQGAYLERAMYMARYDYAPWVGAMFVWNLNFAVTSPDPLHETASFGVLNPDWSPRPAYTRLQQFAATHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W4</accession>
    <name>A9B2W4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3391"/>
    <dbReference type="EnsemblBacteria" id="ABX06027">
        <property type="protein sequence ID" value="ABX06027"/>
        <property type="gene ID" value="Haur_3391"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3391"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="RSFIVIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3428-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="123"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="25087" checksum="C9C489F0EF211710" modified="2008-01-15" version="1">MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGFEVCRRIRAQSIVPVMLLTVRNSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGGERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQYLLANAGRVVSNEQVTIHVWGHHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B335</accession>
    <name>A9B335_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4868"/>
    <dbReference type="EnsemblBacteria" id="ABX07498">
        <property type="protein sequence ID" value="ABX07498"/>
        <property type="gene ID" value="Haur_4868"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4868"/>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051474_3_0_0"/>
    <dbReference type="OMA" id="WQVARID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4928-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="47"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="202" mass="22234" checksum="CCDFA1F44E402953" modified="2008-01-15" version="1">MQSPAKQWLRRSIRGLLASLCLAAVIFISTGYIVYRQAQRAELRPVDALLVLGAAQWDGEPSPVLEARLTEAIRLYRLGYARRIIVSGGTGLNDTRSEASVAYDYLIEHSIDPTLIISVAQGSDTRSTLLAVHDEMQRQQIDSLLIVTDPPHLLRALKMAHDYGITSFGAPVKANSPTTNWASIKATSREALAYLAYVLLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B3</accession>
    <name>A9B3B3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRISPR_Cas6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1432"/>
    <dbReference type="EnsemblBacteria" id="ABX04076">
        <property type="protein sequence ID" value="ABX04076"/>
        <property type="gene ID" value="Haur_1432"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1432"/>
    <dbReference type="eggNOG" id="COG5551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050021_0_0_0"/>
    <dbReference type="OMA" id="RHQKPPL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1454-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019267">
        <property type="entry name" value="CRISPR-assoc_Cas6_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10040">
        <property type="entry name" value="CRISPR_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRISPR_Cas6" evidence="1">
        <location>
            <begin position="187"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="35215" checksum="99306FE218A35116" modified="2008-01-15" version="1">MELLPDLPLVHLRFAYRFMAETRLPRWKGALLRGGWGRALSKVFCIPTCENVSDCQIACPYRNLFAPEAPPNQLVGVREAPRPFIVRPPLDEQTQFSVGDRLSFDLILVGSAERYVIPIIAAFEHLGRLGLGEDRAMAELSQVDSFSSQRQQFIPLLKDGQWFGMAAQLQPQFFLDHAQRFESRWQLQFVTPTRLKQQGQLARQFDLPLIVGAALRRMQQMNSLYGTKLWNCDLDRLFTQARAAQFEAANTRWVEWGRTSAATGQNMQFGGVVGTIDFSRVTPELTALLLMASALHIGKAAVFGNGWFRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B4</accession>
    <name>A9B3B4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyanovirin-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04077">
        <property type="protein sequence ID" value="ABX04077"/>
        <property type="gene ID" value="Haur_1433"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1433"/>
    <dbReference type="HOGENOM" id="CLU_2035777_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1455-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15131" checksum="E2F15AF4CABD5EF6" modified="2008-01-15" version="1">MSVQEQAKEYVPAGSYQRTSQNINVTLTALCQKNDGSWVQSPPLSYSANQAGSITDLANMDGVLTLFTDNPANHNVSDNLGPFVPAGSYQRTSQQVSVTLNAVCQKIDGQWVPSQPLNYTAEQAANAKDIANRDGNLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y7</accession>
    <name>A9B3Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK domain protein ATP-grasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3487"/>
    <dbReference type="EnsemblBacteria" id="ABX06123">
        <property type="protein sequence ID" value="ABX06123"/>
        <property type="gene ID" value="Haur_3487"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3487"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_992956_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3524-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="76"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="32353" checksum="A1EB2C2F9FDCDC49" modified="2008-01-15" version="1">MNPNIRLLSLACERLGLTYEHLHSTENILRIVGPTRNWLFVNWKAPLNDNTMSEICRDKDYFYTLTHNWIKQPQTESYFHPLGPDRFAKYRAFDSLEAIADDVLAKFALPVMIKRNRGSGGLNVFRCHDREGIIRALTKIFDGASKDFDYIALAQGTIEIAHEYRAVFLDGQLILLYEKNIDQAMFEGNLSPLHWNGGRAVVIDDQALHTTISNFAASLFEALPLRWTGLDIAQDRNGEWWLIEANASPGFEYIARDAGDDVIVGVYTHVLQTLGVVSPKLVGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z1</accession>
    <name>A9B3Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3491"/>
    <dbReference type="EnsemblBacteria" id="ABX06127">
        <property type="protein sequence ID" value="ABX06127"/>
        <property type="gene ID" value="Haur_3491"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3491"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760240_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3528-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="40355" checksum="59B96916714994BF" modified="2008-01-15" version="1">MERQQVQVRLASSADYPAVIAVTYAAYAPQRAKSELYAYVYNETVESLSASQAKHPNWQILVVEEAGQIVAAVRVGTFSPTDTDLHLWRLSVDPAAQGRGYGKLLVQTVEQWASAQGYQSISLGALEVSPENQAMYERWGYRYHERREMTSAPGNFYAILHKPTERMANQTVATYETIADDYQQRRGAISAWTLKSRDRFMHYLAAPAKILEVGCGPGRDALMLREAGYQVVGLDPTWAMLQFAKQAEVALVAGDARSLPIAAASVQGVWAQASLLHLPHLEFSLALSEIARVLQPHGICYLSLKIGEGEQMQADGRFFAYHQPELVAKALAGVGLHVLEQWNIDDSRPNCPPWVKTIARKEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B492</accession>
    <name>A9B492_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Penicillin amidase</fullName>
            <ecNumber evidence="7">3.5.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4995"/>
    <dbReference type="MEROPS" id="S45.003"/>
    <dbReference type="EnsemblBacteria" id="ABX07625">
        <property type="protein sequence ID" value="ABX07625"/>
        <property type="gene ID" value="Haur_4995"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4995"/>
    <dbReference type="eggNOG" id="COG2366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011790_0_1_0"/>
    <dbReference type="OMA" id="EMDVRRH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5058-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008953">
        <property type="term" value="F:penicillin amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="821" mass="89939" checksum="511850D822766B1D" modified="2008-01-15" version="1">MATPAKRSLRDRPPLQRWFILFLRFLLIVVLLLLLASGGGYLYLRRSLPTTAGTLTLAGLAAPVDVLRDQYGVPHIYAQSETDALMALGYVHAQDRLWQMEFQRRIARGTLSEALGETTVETDRFLRTLGVYRAAESAYVALDPAAKTIVDAYVSGINAFLAEHSGGELSPEFTLVGVEPEPWVGADVLGWAKMMSWDLGGNYSTELLTMELVAKLGSEKTKDLVPHYPSDGPLIVPNPSGGSQAEQLLALSRRVEQGLGIGGGNIAGVGSNNWVIGPSKSATGKPLLADDPHLSFRTPSIWYMAEVEGGDLHSVGATIPGLPGVIVGHNQRIAWGVTNTGPDVQDLYRETLDPTGTQAMFKGSYEPLTIISDTIRVKDKGNLPLTIRVSRHGPLISDALNANNADDPDAPQREALAFRWTALDQTDNTINAYLAINKAQNWQEFQAGLESYVAPVQNFVFADVDGNIGYMAPGHIPIRANGDGTMPADGASGDYEWTGFIPFEQLPQSYNPPQGYIATANNKVVADSYPYFLSHEWATPFRAQRITKLIEAKPTLTMDDMAAIQADVHSTYAEELLPVLLNLVQPTSDQQRQAIAMLQNWNYSTAGDQPAASIFEAWTYYLTVPMVGDELGERLLETYGQRRQLIDLAIPAMLQDPNNSWCDDVTTTSSTENCNAIVTQALDVALKDLSFRMQDKPMEQWRWGTIHLALFPHNPLDAIGPLRGFFSKAIESAGDGSTVNVGHVADGEPFDQDRGPIYRHIVDLGDFANSRMINAPGQAGHFLSPHYDDLLERWQKVEYIPMTYGRAAVSAGEVEMLQLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H3</accession>
    <name>A9B4H3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04138">
        <property type="protein sequence ID" value="ABX04138"/>
        <property type="gene ID" value="Haur_1494"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1494"/>
    <dbReference type="eggNOG" id="ENOG5031XRX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1466278_0_0_0"/>
    <dbReference type="OMA" id="WMIMCIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1516-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="19312" checksum="23817109B66D3C38" modified="2008-01-15" version="1">MDQSISEAQADMRDGYYSGAAGILASALAWSIAAGVALTGSAERSIWALLLGGMLIFPVSILISKALGARGTHTKGNPLGQLAGASTFWLVFSMPLAYGLGQQKPSWFFMAMLLVIGGRYLVFATLYGMRLYWVLGLVLAAVAIALAFLAAAPAIAASAGAATEMVFAIICLVQHRQSLRQAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4M9</accession>
    <name>A9B4M9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1551</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1551"/>
    <dbReference type="EnsemblBacteria" id="ABX04194">
        <property type="protein sequence ID" value="ABX04194"/>
        <property type="gene ID" value="Haur_1551"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1551"/>
    <dbReference type="eggNOG" id="COG1496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065784_0_0_0"/>
    <dbReference type="OMA" id="CFADCVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1575-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29099" checksum="1C7CE38A12D84D87" modified="2008-01-15" version="1">MIEQIQRLLGYPELIHGISTRQGGVSVPPHATLNLGFSRPDDPSAVLANRRRFADRVGFRLDDVILAGQVHGTTVAVVGELQRGRGAIDRETTLPPADGLVTNQPGLVLWANFADCTPLLFFDPVAQAVGVAHAGWQGTVNNIAQVMISTMQAQFGSEPANILVAIGPAIGPCCYEVDQPVIGAVEQAFAEHTSQVLLRQLGKQRPHFDLWAANAHWLEQAGIQPANLIRMNMCTACHHDRFFSHRHERGATGRFAAVIGLREVHHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4P4</accession>
    <name>A9B4P4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1566"/>
    <dbReference type="EnsemblBacteria" id="ABX04209">
        <property type="protein sequence ID" value="ABX04209"/>
        <property type="gene ID" value="Haur_1566"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1566"/>
    <dbReference type="HOGENOM" id="CLU_1208440_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1590-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="229" mass="26706" checksum="F6B057BDE0C6D16D" modified="2008-01-15" version="1">MRSFILKLLGKKNNPSSPVLPKPIPIPMPPTPAVLGKWPVTSNGVLPTDHRFRWDETWRWINSLPKPRQHMLMQLGVGLIFPSFMLRHVAYTTHWYESPMDWLIYGRGLYAFFQQPDRLRSYLYGATISPVERTQLIELRSSKLFIGQQAAWKYIDSLECPITRELLAATLSYALPFLRDDPDYQTRYPTNPLDLYLFVVAASDVLWRIDKIQQIIDGEVNSLEEFDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4T3</accession>
    <name>A9B4T3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3018</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3018"/>
    <dbReference type="EnsemblBacteria" id="ABX05656">
        <property type="protein sequence ID" value="ABX05656"/>
        <property type="gene ID" value="Haur_3018"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3018"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_4_0"/>
    <dbReference type="OMA" id="HLHLMET"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3050-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="639" mass="67064" checksum="49072B6F87ADABB7" modified="2008-01-15" version="1">MTTTSVNSRHLHAEAQAELDELAALPWMMRLTAICLIATGLGWVAGSFAGVPTWLPWLLYVVAFASGGWFPLGNAWESLRQREFDVNFLMIVAAIGAAAVGQPREGAILMFLFALSNTLETYAMGRTHRAVNALLEMAPDQATLIAADGTQQVVAVADLAIGDRVLVRPGERIPVDGIVRIGASSINEAAITGESVPVDKGAGSKVFAGTLNTTGALTIEVTVAVGDTTLARIIETVAEARSQKAKAQDFTDRVIGQYYAYAVVVMTLLAIAIPLLFLDWSVKTTLYRAMALMVVASPCALVISIPAAMLSAMANAARHGMLFKGGRYLEAAAKIKVVALDKTGTLTTGQLSVMQTVDLGQRPTEQWLIAAAAVEAFSEHPLAKAIVAHAQDQKLNVPTAVDFQSITGMGAQADVHGELVQVGRPRLWGEAVLAQAAKLEAQGATVIGVGTTEQAWGLIALADTIRPDAKQAIAALHAAGVERVVLLTGDNQAVAQHVASQIGIDDVRAELLPGDKAQIIEELQQRYGPVAMVGDGVNDAPALATAQLGVAMGVAGTDVAVQSADVLLLSDDLLKLAEALRLGRRTQRIVWQNIAFAGGVIVVLIASALFGNIALPLGVVGHEGSTLLVVANGLRLLRR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B543</accession>
    <name>HEM1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="1">GluTR</shortName>
            <ecNumber evidence="1">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemA</name>
        <name type="ordered locus">Haur_3544</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B543"/>
    <dbReference type="SMR" id="A9B543"/>
    <dbReference type="STRING" id="316274.Haur_3544"/>
    <dbReference type="EnsemblBacteria" id="ABX06180">
        <property type="protein sequence ID" value="ABX06180"/>
        <property type="gene ID" value="Haur_3544"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3544"/>
    <dbReference type="eggNOG" id="COG0373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035113_2_2_0"/>
    <dbReference type="OMA" id="FAFKCAA"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000093146" description="Glutamyl-tRNA reductase">
        <location>
            <begin position="1"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="47"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="111"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="185"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <sequence length="414" mass="45982" checksum="F5117B3104B853BD" modified="2008-01-15" version="1">MQLVVVGAHQRTAPISIRERIAFAEAELAQALSSLRQIAVEGFILSTCNRVELYALVEEADGGRSLRQFLAQQRSIDLDELMPHVYTYLDEDAVRHLFRVASGLDSMALGEAQILSQIKTAYNAAQQTELLGTTMHRLIQAALTTGKLVRTETQLAHAQLSVVSVGLSLARQHLDLTNRSVVIIGAGRTGELALKHYLEYTSNITVLSRTFERAARLAEHHKVAAKPISELAAVLQASDVVISCTSSPELMLDFEQAQLLQAQRQRQWVLLDLAVPRDIDRHVGALPEVWLYDVDDMQAICERNRASKAAEVAGAEAIVERELIKWQEWWLTQAVLPTIRALRAHAEAIRLAELERTLARLDLSEQQQQAVSALTSAIINKLLHQPMRAIKDTAASPQLAHAAQQLFRLDFEAI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B550</accession>
    <name>GSA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="1">GSA</shortName>
            <ecNumber evidence="1">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="1">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hemL</name>
        <name type="ordered locus">Haur_3551</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B550"/>
    <dbReference type="SMR" id="A9B550"/>
    <dbReference type="STRING" id="316274.Haur_3551"/>
    <dbReference type="EnsemblBacteria" id="ABX06187">
        <property type="protein sequence ID" value="ABX06187"/>
        <property type="gene ID" value="Haur_3551"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3551"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_0"/>
    <dbReference type="OMA" id="AQTWRFP"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000201023" description="Glutamate-1-semialdehyde 2,1-aminomutase">
        <location>
            <begin position="1"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <sequence length="429" mass="45394" checksum="35E675D4A76DC45F" modified="2008-01-15" version="1">MINDASSAAFERAQALLPGGVNSPVRAFRGVGGVPRFIDHGAGAYLYDIDGNQYIDYVLSWGPLILGHAYPAVVEAICAQAQRGTSFGAPTELESELAELVIAAVPSVEMVRFVSSGTEAAMSAIRLARAYTQREKIIKFEGCYHGHADPFLVQAGSGVATLGLPDSPGVLKSATSNTLTAPFNDLEAVEALFKANAGQVAALVIEPVAGNMGFVLPREGYLAGLRQLCDQYGALLIFDEVMTGFRVAYGGAQAYFNVMPDLTCLGKVVGGGLPAAAYGGRREIMQMVAPAGTMYQAGTLSGNPLAMVAGIVTLREIAKPEVFERLTGVTSTLCQGFWKAAFKNGIPFQAHKAGSMWGFFFAGDEVYDFTSAKRADTAMFGKFFHAMLEQGVYLAPSQFEAAFVSTAHTDELVAQTINAAQAAFASIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B560</accession>
    <name>A9B560_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gln_deamidase_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3561"/>
    <dbReference type="EnsemblBacteria" id="ABX06197">
        <property type="protein sequence ID" value="ABX06197"/>
        <property type="gene ID" value="Haur_3561"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3561"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1459429_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3598-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041325">
        <property type="entry name" value="Gln_deamidase_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18626">
        <property type="entry name" value="Gln_deamidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln_deamidase_2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="185" mass="21151" checksum="2841A8339293D8BA" modified="2008-01-15" version="1">MQVNQDGSVSYADATLIFDDMANEADIPFNFKDDGCYARSYLMGNRIVERYGINPDDMFKVTILDRSPSDSNPTLTVPTDKMYPGFSSEDGTVNWTWHIAPAIKVQTPNGVEIMVIDPSLSTHPLSVDQWEALMNDPQSNVEIKDHSWYTPWDQVTPENKPFFDDHAQKTMEEYMRYCQEAGYCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B591</accession>
    <name>A9B591_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3592"/>
    <dbReference type="EnsemblBacteria" id="ABX06228">
        <property type="protein sequence ID" value="ABX06228"/>
        <property type="gene ID" value="Haur_3592"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3592"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_721135_0_0_0"/>
    <dbReference type="OMA" id="NAPYLWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3631-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="206"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="39042" checksum="11AB4C91AEE3AA9C" modified="2008-01-15" version="1">MHPLQTTIDQYAAQFDRRRMTILAAHVEEDNGTVLRGRVLDRSQHAALLALLPNVRDELIVLREQPEHGFATVTFGVLDVRWQATRDSELVTEASFGEGLEVLAHEHEWLQVITSDGYLGWVRRNGVVLHEQPSTYRSAATHVVTSRWLPLWGLEGDQIGLLPWGIRLEIDEFRDGKAFMRSPAGLPGWLEADSLTPVEDLCSVDSAGIEDMLQAIRQLIGVPYLWGGTTSFGFDCSGLAQAAYRWLGVQLPRDADQQSQIGRLISREQVAAGDLLFWGVLRNIEDYRHERINHVSIALDNEWMIHANQRNWSISLDRIDEVNAQVYQAQGNPGLVVIRRIREEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A9</accession>
    <name>A9B5A9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0082"/>
    <dbReference type="EnsemblBacteria" id="ABX02734">
        <property type="protein sequence ID" value="ABX02734"/>
        <property type="gene ID" value="Haur_0082"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0082"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082131_0_0_0"/>
    <dbReference type="OMA" id="EAPHRGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-83-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27340" checksum="BCE3A5387FAC8663" modified="2008-01-15" version="1">MFYVLMYQHICLSPHFDDAALSLGGALAGWHAAGERCLIVTICSAPPSGELNQFAAYLHERWGAASDPIAIRRAEDQAAANRLGADLLFLEQHDAIYRHAGYDSAAAIFGTPIADDLLWASLTTQLQALVQQYPDAIWYAPLAVGNHVDHQITHGVAAKVLSNVRWYEDLPYSARNNARDQRLAQVQPTLDQVIAIDQTLAIKLASVADYASQIFELFGTVAAMEQELSTYAASVAEQGFAERLWRGGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H0</accession>
    <name>A9B5H0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0143"/>
    <dbReference type="EnsemblBacteria" id="ABX02795">
        <property type="protein sequence ID" value="ABX02795"/>
        <property type="gene ID" value="Haur_0143"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0143"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065902_0_0_0"/>
    <dbReference type="OMA" id="ACPAIER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-146-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="175"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="259" mass="28136" checksum="C65A054A3243C474" modified="2008-01-15" version="1">MSLKYLLIGALTRDRTATGWQQGGTGTFAARALAAWGVATTIITPAHAKLIFDLPSTSTLVRLPSRATATFENRYQGDARTQWLHAAPTQLDWANLAPYWQQASLVHLAPLAQELTTIPPRKLFPQALIGLTAQGWLRHWDSSGRIQPKRWQPTPTELAQIDALVVSDEDVAGDVQLVADWAQHCGLVAMTQGSRGATIWVNAEVQHVAAYPAQVSDPTGAGDVWAAAWFWRIQQGSSALQAADWACQQAALQISGQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5U0</accession>
    <name>A9B5U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3095"/>
    <dbReference type="EnsemblBacteria" id="ABX05733">
        <property type="protein sequence ID" value="ABX05733"/>
        <property type="gene ID" value="Haur_3095"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3095"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041908_0_0_0"/>
    <dbReference type="OMA" id="GFENRES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3127-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="105"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="201"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="296"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="501" mass="54713" checksum="B77F054600D8CEFF" modified="2008-01-15" version="1">MTDEAQNVSATNGGEEQEEGVLQKLADKAREVVAEVKEELAEVKEEIGEALAEAREKASEVLAEVKERVGLGGDDEATEEAGATFEPSGDEDGTTPRRLADLHAGMELDGKVTSTALYGVFVDIGVGRDGLVHISEMSDQRIESPTDVVQIGDIVKVRVKSVDPDARRISLTMRSPRSEGRRRAPKRPEVNNDKLGELKPGDLVDGTVNGIAPFGVFVDIGVGKDGLVHISELSENRVEKAEDAVTVGQSYTFRVLEVDTGAQRISLSLRRAKEDFQERPKAPRRREVNLDVIAPGTVLDGKVSGIAPFGAFVDLGVGRDGLVHISELSEGRVGKVDDVVKVGDPVKVRVLEVDPDSKRISLTMRVEEAPTTPISTSGSSRLDRDWTNPASREERPREERRAVGGGNPGGNPGGGRRNDRRDRPAREPEIYSVGGTEEEDFGGNATLDDLLSKFGSGHDDRRSARRRYEKPEQEEEDGFENRESRARRDAIRRTLRDSQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V7</accession>
    <name>A9B5V7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase</fullName>
            <ecNumber evidence="3">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3112</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="3">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="2">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="2 3">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3112"/>
    <dbReference type="EnsemblBacteria" id="ABX05750">
        <property type="protein sequence ID" value="ABX05750"/>
        <property type="gene ID" value="Haur_3112"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3112"/>
    <dbReference type="eggNOG" id="COG3733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_5_5_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3144-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
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        <property type="term" value="F:primary amine oxidase activity"/>
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        <property type="term" value="P:amine metabolic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
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        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
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        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR10638"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0801">TPQ</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735476" description="Amine oxidase" evidence="4">
        <location>
            <begin position="32"/>
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        </location>
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            <end position="388"/>
        </location>
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    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="1">
        <location>
            <position position="172"/>
        </location>
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            <position position="172"/>
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    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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        <source>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX05750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="43749" checksum="4FC83C091131F211" modified="2008-01-15" version="1">MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEERSSEGIVLRGIRYTPPGGSQISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMVAADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSALVLRSVSHIGAYNYVSQWIFHDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVVEQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSDHVFRGPTFEPWTNNDVYVTENNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITFHHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B611</accession>
    <name>A9B611_HERA2</name>
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        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein transmembrane region</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3167"/>
    <dbReference type="EnsemblBacteria" id="ABX05804">
        <property type="protein sequence ID" value="ABX05804"/>
        <property type="gene ID" value="Haur_3167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3167"/>
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    <dbReference type="HOGENOM" id="CLU_053225_2_0_0"/>
    <dbReference type="OMA" id="YLCFLAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3199-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
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        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
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    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
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        <location>
            <begin position="48"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX05804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="32114" checksum="0667DF32CE4EC702" modified="2008-01-15" version="1">MQQAQTQRQPSRLFTMAIIGLAVFVVAAILLIGVAQGGQNVITLAVPAFMAGVLSFLSPCTLPVLPAYFAWTFGINSAGDESLAQKRQRTIISSLAFFAGLATTMVVLGMAITATSQAIRGISSNKDLFAQIGGVIIIVMGVMSIFGIGFTGANIKRSSSATVGSAYLYGLTFALGWTACIGPILGAILTLLISTGASIIAGATLTFIYVLGLALPLMIVATFFNKLGQGSKGWKLLRGRALEFNIGKRVVILHSTSVISGILLIAVGILLVTGQMSTLNDIALDNPISKWANNVQYDIQTFFTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B626</accession>
    <name>A9B626_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA mismatch repair protein MutS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3182"/>
    <dbReference type="EnsemblBacteria" id="ABX05819">
        <property type="protein sequence ID" value="ABX05819"/>
        <property type="gene ID" value="Haur_3182"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3182"/>
    <dbReference type="eggNOG" id="COG0249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030717_0_0_0"/>
    <dbReference type="OMA" id="CQNMNAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3217-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
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    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="4">
        <location>
            <begin position="423"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="618" mass="68314" checksum="C7EFE486835CC770" modified="2008-01-15" version="1">MSLPNQATPIETYRQRSASYQLELEQLRQRSDRFANLRLVLFGAALFAVIFGFANAPWWFAVAVGLLIGFVWVLIQHNTVEEQRQRTQALYQLNHYGVQRLERDWVNLPLRVPSLDIPADSYANDLDLVGRASLLHLLGHLPTALGLDTLLSWLLAPANPSTITSRQQAIAELAQNVQLREELHVAAHHVTAERADFEQFLVWTEQPAQVLNRMWVVWLARLLPIGPIAGLVAYLAGWTNVPYWLVLFILNIIVSNGLGLWANQVIMAVSARRKGFAGFGALFRAINEPQFQAALLRQAQSQLTANGVRADHQMARLSRLLSLADQRFSYFYIVLQGFSLWNIHIGWLLERWQRDVRGQARAWLTTLGEIEALAALATLQADHPNWTQAQLHTTDQVIASGLAHPLLRPDKAVANDLSIGPAGTLFLITGSNMAGKSTLMRAIGLNIVLAQTGSVVCASNLQLPVLRLATSMRINDSLEQGVSYYMAELLRLKMVLGEVEQARAAGQPALFLLDEILHGTNTRERTVAARHIIARLIGLGAIGAVSTHDLSLATAPDIAAISQPWYLTEHFERGDNGPSMTFDYQLRAGLAPSTNALKLMEIVGLVDQDVPLSVAANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B5</accession>
    <name>A9B6B5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3690"/>
    <dbReference type="CAZy" id="CBM20">
        <property type="family name" value="Carbohydrate-Binding Module Family 20"/>
    </dbReference>
    <dbReference type="ESTHER" id="hera2-a9b6b5">
        <property type="family name" value="A85-Feruloyl-Esterase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06326">
        <property type="protein sequence ID" value="ABX06326"/>
        <property type="gene ID" value="Haur_3690"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3690"/>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620764_0_0_0"/>
    <dbReference type="OMA" id="HEREWIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3732-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="49581" checksum="0CC8701A46688428" modified="2008-01-15" version="1">MWLTLILFVVGLGLAFGLGVMVGRQRGFALFSAPEATPLVNFEFKIPADTAPGDQLYLTGSFNQWRPNDPTYVLSRSADIAYGAWPFTNGLRLDFKLTRGSWSNVEKAADGSEMPNRTGIAASGAQVKGTVAAWADRQRDAAKIYDERVERVDFFSQALGITRTFYIYLPIETRSDENLRVPSLYLFRGHEREWINKTEDGTRGGNRNVIDVYEELRRQDQIGPMVMVFPGMTNANDGIHSLGINLHSPELVADPSIGTGLFEDFIYRDLIPYVETHYPVLFGGAHRSLDGFSLGGFISVNQALRHPNEWASVGAYDGLFFWDDPENAEIIAARDSVFERNLFDANFGVPRDHTFAAQHNPLTLLRIDGAQASKLQWLIEYGPESAEPNVNYYRGARLDELLREVGAHNRLSGVVPNANHSWQMADEHMRRSLPYHYQQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C2</accession>
    <name>A9B6C2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0173"/>
    <dbReference type="EnsemblBacteria" id="ABX02825">
        <property type="protein sequence ID" value="ABX02825"/>
        <property type="gene ID" value="Haur_0173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0173"/>
    <dbReference type="eggNOG" id="COG1146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_0_1_0"/>
    <dbReference type="OMA" id="DRMLYIH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-176-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8445" checksum="C0F3A9EB2BCBD47D" modified="2008-01-15" version="1">MAYVIAEPCVGTKDSACVKVCPVDCIYEGEDQYYINPDECIDCGACEPECPVSAIFSSDSVPEQWASYTQKNVDFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6M1</accession>
    <name>A9B6M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1687"/>
    <dbReference type="EnsemblBacteria" id="ABX04330">
        <property type="protein sequence ID" value="ABX04330"/>
        <property type="gene ID" value="Haur_1687"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1687"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_0"/>
    <dbReference type="OMA" id="PPYSLFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1711-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="16"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="310" mass="34240" checksum="CA4B6315079E6DB0" modified="2008-01-15" version="1">MEYRRLGKAGMRVSAVSLGAWLTYGGSVEGDQAAQCLRAAIDNGINFIDVADAYAYGEAEKVVGGVIRDYKRSDLVLSSKLYWPMSNNVNDQGLSRKHIMESIDKSLRHFGTDYLDIYFCHRFDANTPLEETVRAMSDLVQAGKILYWGTSVWEAEQIEQAVSIAKQYNGYLPQVEQPRYNMLDRHIEPAIIPTCEQHGLGLTVWSPLAQGLLTGKYNAGLPEGSRGATTKWLDRELNENNLNKVRQLTTIAGDLGLTTSQLALAWVLRLPQISSVITGATKPEHVLDNIKAGEVQLSADVQAQIEAILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P3</accession>
    <name>A9B6P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04352">
        <property type="protein sequence ID" value="ABX04352"/>
        <property type="gene ID" value="Haur_1709"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1709"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1358874_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1736-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="31"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="201" mass="23173" checksum="69FAA708635D41E0" modified="2008-01-15" version="1">MHDTMTSTTLYAACFEQDSLAQHEAYTTLWNMLYRVAYAMLHEYPDGDAITTDCTQKALIKIHRNIEQCQNPATFREWCMQIVRRTVLDELRRPEHRRRASMPDAEHGPWVAPIETLQLDDLRAILNEVIEEGPLSARSRRVVVGRYFSEQNDDILAQTESELAQKPVLASHIQVTRAKNLAALRRDPALIARLREFVEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R4</accession>
    <name>A9B6R4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04373">
        <property type="protein sequence ID" value="ABX04373"/>
        <property type="gene ID" value="Haur_1730"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1730"/>
    <dbReference type="eggNOG" id="ENOG502ZNTW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1625445_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1757-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18263" checksum="C2BB61563D8BF9BD" modified="2008-01-15" version="1">MNLKLFPKHYYAALEAVAETHQAALQKLMTEFEIYAANSGFSELIVTYNQAPTIIQRCAEQGIAISALSWWCHVTPANQTAFGCPHGFGGPVTRIGRLSECNQYPEFEIVPPTNGWPSQTQAIALHCAQQLTSFIAQQLPLEPFYRPCLQIGLALAVPDWQRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6T6</accession>
    <name>A9B6T6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1752"/>
    <dbReference type="EnsemblBacteria" id="ABX04395">
        <property type="protein sequence ID" value="ABX04395"/>
        <property type="gene ID" value="Haur_1752"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1752"/>
    <dbReference type="eggNOG" id="ENOG502Z7NX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046986_0_0_0"/>
    <dbReference type="OMA" id="VREGECK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1779-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734595" description="DUF11 domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="354"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="465" mass="50412" checksum="1386AA793E464F01" modified="2008-01-15" version="1">MRRMIVFAIVVLLMAACSSQWPSAPIAKSTPHNPANFPPSPQNSPTIGQCPVFPLDNIWNTPIDTLPVHPRSSQYIASIGGSETLHPDFGAAQWNGGDIGIPYVVVPANQPTVTVNFVDYPHESDPTTGSGQYPVPPNAPREHGSDHHVLVVREGECKLYELYNATKINDTTWNASNGAIFDLRSNSLRPDTWTSADAAGLPILPGLVRYEEVQAGEINHAIRFTIQRSQRAYVWPARHFASSITDQNVPPMGMRFRLKASFDISGFSSEMQVILRAMQRYGIIVADNGSDWYISGAPNPNWDDDNLVSSFDQIRGDHFEAMDSSSLQLNPDSAAVIASAAPQPSKLAEFGGVDQGQQLRYAITVVGTGSPQTMNDQLPDGLTIVPASATINPSNLAAPAISNNSVQWSGTIPNSQSAVISFRATVSTNERRVIINTAQINAATVQASIIANGYRVWSPMVRKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B767</accession>
    <name>A9B767_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06350">
        <property type="protein sequence ID" value="ABX06350"/>
        <property type="gene ID" value="Haur_3714"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3714"/>
    <dbReference type="HOGENOM" id="CLU_2569166_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3756-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="8580" checksum="718D357BCF0EEC5C" modified="2008-01-15" version="1">MHCPKCTNDMTTSALVTPDGVEIMVMGTLATGHRPLSAQVCSACGFTELYAAQWTEEIQQARETAVLEAEPIAIASAEPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E4</accession>
    <name>A9B7E4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0265"/>
    <dbReference type="EnsemblBacteria" id="ABX02917">
        <property type="protein sequence ID" value="ABX02917"/>
        <property type="gene ID" value="Haur_0265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0265"/>
    <dbReference type="eggNOG" id="COG1898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090940_1_1_0"/>
    <dbReference type="OMA" id="RGVFLEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-268-MON"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="20937" checksum="9AEF9C510B9FE8A8" modified="2008-01-15" version="1">MSLTVTQTALDGVVIIKPSVFADERGFFLETYHQIKFADLGLPTDFVQDNHSRSKQGVLRGLHYQDERQPMAKLVRCSVGSIFDVAVDLRVGSPTFGKWVGVELSADNFLQFLIPSGFGHGFVVLSEFAEVQYRCTGLYAPETEGAVRWNDPQIGIEWPISEPTLSGRDQAAMSLADYLENPAFRYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7F8</accession>
    <name>A9B7F8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02931">
        <property type="protein sequence ID" value="ABX02931"/>
        <property type="gene ID" value="Haur_0279"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0279"/>
    <dbReference type="eggNOG" id="ENOG5033PTS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512653_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-282-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="531" mass="57409" checksum="3EC829291A81023B" modified="2008-01-15" version="1">MRIIHRSEQTIQTAHHYAERAAHHGDAVFDGVSIPPEISARNWALEGTVHSTKIVTNQLDSTRYFLGPQVCITHDDNRRTTWAAHVEHAQADQAHGQLILSQFIGPNPAAAAASLSPAMRYVPQLERTIIAEGEIWRYHLTLNKFTGTIVTTWITRSAKGLQLWLDGTLVNTESSEVDFPFFGLSQVAVGHVATAPPPFGLLSYKCRNTGRLFIRRYVDGQLGPEVGLDVGEIRGGLSFGISGKQILARVDRITAGGLVPTLLRSADGGKSFDKPHAIDLGGYDQDFKLIPGYTEPIVDKGGAFHVPIILSNGRESVALNYIPEHETIVEAIRVTGGNPLGKLAVFPSTVGSKTSFGNGTSDGHGLIMILATEGRLFTSNSSAGGIYFPEAVLLNHEMPLIAGFAASECYSSGLKPNIVSMDYIYLEANSIGQVASPTLHYETWDMPLPLPQATAKSKGASVAITIQSDADVEPGKVVFNFDDPSIVITNSTITSLRTATLETNTPKLSGKKVSFDILTLFHRHYGEAMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I0</accession>
    <name>A9B7I0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0301"/>
    <dbReference type="CAZy" id="GH116">
        <property type="family name" value="Glycoside Hydrolase Family 116"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02953">
        <property type="protein sequence ID" value="ABX02953"/>
        <property type="gene ID" value="Haur_0301"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0301"/>
    <dbReference type="eggNOG" id="COG4354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006322_1_0_0"/>
    <dbReference type="OMA" id="TSPVMEN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-304-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014551">
        <property type="entry name" value="B_Glucosidase_GBA2-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006775">
        <property type="entry name" value="GH116_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024462">
        <property type="entry name" value="GH116_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04685">
        <property type="entry name" value="DUF608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12215">
        <property type="entry name" value="Glyco_hydr_116N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028944">
        <property type="entry name" value="Beta_gluc_GBA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydr_116N" evidence="2">
        <location>
            <begin position="44"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="DUF608" evidence="1">
        <location>
            <begin position="403"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="774" mass="86230" checksum="F6D2165F84264861" modified="2008-01-15" version="1">MTEQRHHSSIPLAAWQRPLGLDYPNAAIAAHDHGPIIDDGVFHGLPIGGMGSGAIGRNFRGDWSRWHLEVGKHVHRSVWPNQWSVFWQTASQQAAQVLCTTQPDTDELSSWNWNYPVGAGNYHALFPRAWFDYQHPDWPLELVQEQFSPVLAGNLKESSFPVGVFTWRVTNRGSETVRLGLMLTWEHTRAVEAAGLSLQRQHSAWNDGNTSGVTLTQTSDQALSSHNGTWALAVQAPESASVSQWTCWDVAQDAAALWQDFASDGQLADYPTSQKVAADQRSATAIAVTLELAPGASAVIPFSLAWDFPIVEFADQSRWYKRYTRFWGTNGDQAQALAVASLTNADAWRTAIEAWQNPILADDQRPFWYKSALFNELYYLVDGGTLWVDRAVGGPEPAADDVGLFSYLECYDYPFYGTLDVSFYSSWSILALWPELERGEILAFSKTVNDADDTVVTIVATQVPAIRKAAGALPHDLGAPKEQPLIKTNAYDFQDINNWKDLNLKYILRIYRDVSLWNDQAMLEATWDTIPTALEYVHQFDSDGDGLLDHSGADQTYDTWAMSGAASYSASLLICALEAAIRLAQRMGDHAQADAWSEWLAAARQSFETKLWNGTYFRYHTADTDLREVIMADQLVGQWYAGAIGLPAVAPREMIRSALQTVYRFNVMQYANGALGAVNGMHPDGTVDTSSNQASEVWSGTTYAIAAMMLQEGLDLEGWQTAWGAYNATYNELGLWFRTPEAWGIERTFRASMYMRPQSIWAIEHALAVRAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N3</accession>
    <name>A9B7N3_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0355"/>
    <dbReference type="EnsemblBacteria" id="ABX03006">
        <property type="protein sequence ID" value="ABX03006"/>
        <property type="gene ID" value="Haur_0355"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0355"/>
    <dbReference type="HOGENOM" id="CLU_2142437_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-358-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12400" checksum="351C943742DC1632" modified="2008-01-15" version="1">MLNPADQLLLKSLCNDLVAVEAQISELETQRESLRARISELVEQMGGKIQLRGFGTLQISNPSVIVSYDRKGIEQLVQQLAEAGNFALVDAIQTSRKESMRSGGLRIMREKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P7</accession>
    <name>A9B7P7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAAR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1782"/>
    <dbReference type="EnsemblBacteria" id="ABX04425">
        <property type="protein sequence ID" value="ABX04425"/>
        <property type="gene ID" value="Haur_1782"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1782"/>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151895_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1810-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="13185" checksum="CEBB2D323247FD43" modified="2008-01-15" version="1">MGKPAAKKGDQVTGSCMHTVQPPGGPPPPPVQVPHPFVGMINDQLSSDVKIGGQPAAVAGSKAMNTPAHIPTPPNLSFINSPNNQATLEGGSQTVKINGKSAIRAGDQATTCDEAKVKGVVVAVGTVMIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y3</accession>
    <name>A9B7Y3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05916">
        <property type="protein sequence ID" value="ABX05916"/>
        <property type="gene ID" value="Haur_3279"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3279"/>
    <dbReference type="HOGENOM" id="CLU_632788_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3316-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734620" evidence="1">
        <location>
            <begin position="25"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="433" mass="49238" checksum="C70CAE10CA7AE0D0" modified="2008-01-15" version="1">MKWQWVCRLGLLLSLGFFSNPVAATQSQTLSREIVSEHTITQLKLDGNWLAWRTWRTDFVNYTSELWVTNLTTGTSVSLGSIQNETYDFFIDNGRVIWRDKHHVYQYDLATQTNTILQVPHQQNHMRWTVAGDWLIWLELEGSPPQLTNQIWKWHLAGNQAPVLVGSEVATIYGIDSLQSDGEIISWAYATHVVVKNSVCSEIHYLALDGSQAPQKLTEPACNIGIKQNLLLNKNFYYCNNQHLYARTLANTEILINENNCRFDALYGFSGSGNFLVALNYGEHTTSQISVVGVDIRQKSMFTIDRFGYSDSGRPLIHIDNSLVAWSDNRGAKPVIHVRPIAEVVPTAPRQAADPLLENRSYYPESQHSLGGLFEQYWQKNGAWQCLAIRKAKNLAKSMPILVKLIRCNCLSVSATNITLNWLAHHMRFRWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B826</accession>
    <name>A9B826_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3323"/>
    <dbReference type="EnsemblBacteria" id="ABX05959">
        <property type="protein sequence ID" value="ABX05959"/>
        <property type="gene ID" value="Haur_3323"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3323"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048758_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3360-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11537">
        <property type="entry name" value="NTP-PPase_RS21-C6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025984">
        <property type="entry name" value="DCTPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029401">
        <property type="entry name" value="Nudix_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12643">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14803">
        <property type="entry name" value="Nudix_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29623" checksum="6A3393DA7EF28AF7" modified="2008-01-15" version="1">MYCLHCRQRLELRLRGGRERLICPECGWVHFTSAPAGVAAVIQNDFGEVLLVRRAGTFRPGLWCLPCGYLEHDEEMRQGLAREVLEETGLQAEIGEVIAVHSNLDREPPYPLGVWLRATVSGGNLQAGGDADLAQFFALDQLPPLAFNHDALVLAQLQQPADASVAALTQEMHAFVRSKGWYEANSKRPQTPRNLAISLTLEAAEVLEHLQWREEIVDQTEWQGELADVLLYLVQLADTTNVNLVEAVRAKLRKNATRVWDQPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B832</accession>
    <name>A9B832_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3329"/>
    <dbReference type="EnsemblBacteria" id="ABX05965">
        <property type="protein sequence ID" value="ABX05965"/>
        <property type="gene ID" value="Haur_3329"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3329"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_0"/>
    <dbReference type="OMA" id="HEHQPRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3366-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="260" mass="27170" checksum="A4CE5C260119AE73" modified="2008-01-15" version="1">MNLRNTVALITGAGSGIGKATALYLAAHGANVAALGRTEDELTETVETIQRAGGDALALIADITQPDELQAAVDQMLETWGKLNCVFANAGINGVWAPIEQLSLEEWQNTLNINLTGTFLTLQTTVPALKKQGGAIIITSSINGTRTFSNVGATAYSTTKAGQVAMAKMLALELAQFKIRVNVICPGAIETSIDESTEKRAIETVAVPAEFPEGDIPLTHGQPGTAEQVAQLVGFLASDAASHITGTEIWIDGGQSLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B841</accession>
    <name>A9B841_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3338"/>
    <dbReference type="EnsemblBacteria" id="ABX05974">
        <property type="protein sequence ID" value="ABX05974"/>
        <property type="gene ID" value="Haur_3338"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3338"/>
    <dbReference type="HOGENOM" id="CLU_942577_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3375-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734622" evidence="3">
        <location>
            <begin position="24"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="30883" checksum="7E133348F774DCDB" modified="2008-01-15" version="1">MKQWMSRMLLGVLAIALSGCVASQVETTISGDGSGTNTFKVGMDAETMAMMASMGGTEGEDPFKQTKDDVSGYPAEWSATTSDWKEKLGETEFQGVQINMKFANLATLNEQLSQFLTDSGSSDSPTGQALSNLKVTDDGETFTVSGNAMATDLAAAAESEGAGMPGMGDSLKKAVIVWQVTLPGEVSSVEPADIATVNGSTVTWKIPVDKTAQYTLKAVSTKSGGAGGSNLPLILGGVGLLVVLAGVGFFVMSRRKAAPVAAGYQQYGGQTYDPNAQQNQQQGYYDPNNDPNRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B872</accession>
    <name>A9B872_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3369"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06005">
        <property type="protein sequence ID" value="ABX06005"/>
        <property type="gene ID" value="Haur_3369"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3369"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_4_0"/>
    <dbReference type="OMA" id="DADNQYC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3406-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="39389" checksum="12D656E27B0E10D6" modified="2008-01-15" version="1">MATMPMSETYIQPSEPTRSHPWRVIIQIPCLNEEATLPDVLNDIPLDLPNVHFETLVIDDGSTDRTVEVARELGVNYIVRHRGRKGLPAAFQSGMDAALKLGADIIVNTDGDHQYPGSAIPELIKPILEGKADIVIGDRQTQNVEHFSTQKKLLQRVGSWVVRVASDTDVPDAPSGFRAYSKEAGLRLYVTSEFSYTIENLIQAGKRRLNVDHVAITTKPTRPSRLHRGNFNFVKRQGATIIRTYAQYEPLKTFTYFALPFLLIGGGLLLRFMIYYLIDPNQTYTRYLQSVFIGGVFMIVGILTFFIGILADLSGNNRRINEEILYRLRNLEVEVARRLPSNDSDEIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B892</accession>
    <name>A9B892_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SQHop_cyclase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3809"/>
    <dbReference type="EnsemblBacteria" id="ABX06445">
        <property type="protein sequence ID" value="ABX06445"/>
        <property type="gene ID" value="Haur_3809"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3809"/>
    <dbReference type="eggNOG" id="COG1657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_756004_0_0_0"/>
    <dbReference type="OMA" id="CPDGGYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3851-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735527" description="SQHop_cyclase_C domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="SQHop_cyclase_C" evidence="3">
        <location>
            <begin position="132"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="37102" checksum="355560E14B0B5600" modified="2008-01-15" version="1">MLRRAAIHRWLLVLVALFVAMPVAAQAPTEGAKAGAWIVTQAQADGSFPGFGLGETADAVYALKATGLKVDLNVQSFIEKNASAIAAKPGVAAKFVLAELLLGYNPRAVAGTDLVAAVTGSYKADSGMYGGDVTTHALALLALNAAGAPVENKAINTLNSVQIADGSWSFSGDTTAGAGDTNTTALVVQALVAIGQGKSEAVTKALSYLQSQQNSDGGFPYSKASSYGSATDANSTGLVIQAIVATGGNPTAAPWATATGNPLSALLSLQNASGAFRYDAATPDDNAFATYQATPALFYVTYPLTALVTAPQPTAVPSTPVATATPKPNTPITLPDTGAPALPLWPVVIVFGLACIVAGLRLRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H7</accession>
    <name>A9B8H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07641">
        <property type="protein sequence ID" value="ABX07641"/>
        <property type="gene ID" value="Haur_5011"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5011"/>
    <dbReference type="HOGENOM" id="CLU_309678_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5074-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025832">
        <property type="entry name" value="GxGYxYP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038410">
        <property type="entry name" value="GxGYxYP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032626">
        <property type="entry name" value="GxGYxYP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14323">
        <property type="entry name" value="GxGYxYP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16216">
        <property type="entry name" value="GxGYxYP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732005" evidence="1">
        <location>
            <begin position="21"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="GxGYxYP_N" evidence="3">
        <location>
            <begin position="54"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="GxGYxYP_C" evidence="2">
        <location>
            <begin position="579"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="951" mass="105240" checksum="3D93CA25995D90EE" modified="2008-01-15" version="1">MLRRWILLCLVIGIGLSVVPQDTSAQSAVYYTFDAHSLLMNQSDENFDKVAFLLSVQGNVNRESPRLFIKQPQMISVKGSDYSPDTLWKNAIQSSFIWLNPRQYQETVLTDINQVITTFAASSYGIDGSVVWDKDRPWTLNIAASIAGARNLAIVRKQSPIYATLTAHYPVVVDLTTDPIQGFMTTKSSAYQWLLQEYLLNSANPHRLEPTLASLKDGYALKNRAMNTLYFGRWISLEMDAAIARKALIFDLSPNADLGSPEEQCQAPSSDYTTLTTLLQNVRNRKGTQPIEVMGFLDFRYIYCEGNGQPHPTDEQRRLQNVVTALEHPFAKVISQYGGMMTVGGIGPADAANGSFFRHSPGVRYIPQSPAMTPETLLRNDYADGYPLNFSFEKGGVSQWTMWTTNYATYAGTNLPHGSTFLEMNTSTTDWQNGKNTLYQDVPIALLRGSRYQLRLSARRNPSEVGSIQGGIALWGKRANGSYTQLNHCPFTLTSGSWVPIACDTDIREDGLHGIRLQIALYTPDKNYDFDAITFLGPNTLRVNPTKTFGLFYMGDYDGPGAAYSTLMADVNDEKSYNELIWTSKITTTVPVAWAIAPSFRDAYPSAYAYLAKTKGPYDYFMMPNSGPNYTNPLHFDSLASGRPRVGPFKQQTATLNREVGYRVGWVLDGAESHLSYSDPTVRSIFKIATPDGYIHNSNVPPIGPTDPSVATYDGHAAILRKTTDLVDHATTDTDGADRLIAHVLAPQAAQFQVYRSIFVSSNFISHVVSTAKTKNLQFANRFAALDPMSFFGLYKSQHGLYPRLRMSMVSDTLPQVMYTGQSYAVQVTIRNDGWDIWRPKPSGATDCDGSGLAYKGCDRFVWTFQPPTNPIIPTGPGAIPTVTYPSGNRIDFGTTIAPGATTTVNLMLTIPANATLGYHTFQADLVQEGYGFGETYGNQPWQGRVLVATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N7</accession>
    <name>A9B8N7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA_GG_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07701">
        <property type="protein sequence ID" value="ABX07701"/>
        <property type="gene ID" value="Haur_5073"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5073"/>
    <dbReference type="HOGENOM" id="CLU_838806_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5135-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="RNA_GG_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_GG_bind" evidence="2">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="37247" checksum="00AFB2727EC2EC70" modified="2008-01-15" version="1">MRTIMDQLIIISNLAARLQETNDLAITHLKRTLTILGYDHTLSLITEAEALVAQGGIPTNDNTRKRTLGGTFFYLVRRDVSWKDRITIFGLSPSQQAQIFSWKTREVVYNEFSNPGITSSIQSTLSGKPSHAVIQPKRVILSFKIVPPTIGIAKDIQPPQDETFVTAYVSRKHWLRLVDQGYSDTNVTLKGQLFYDEGLEGLSFYAYKLKHTPEALSGISYQCVTSIDQVLIKKNLVLLKTIYNPSVSTIPNYLPPAPTNPTETMLYINRKAWKGIASDRPIHIDGFAYHDPLFSGITVSVRAIKSRGLPKHMRTENEHPHHDLEQTNSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X5</accession>
    <name>A9B8X5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07789">
        <property type="protein sequence ID" value="ABX07789"/>
        <property type="gene ID" value="Haur_5161"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5161"/>
    <dbReference type="HOGENOM" id="CLU_1141345_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5223-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="243" mass="27805" checksum="C21AD16EA9BCDC96" modified="2008-01-15" version="1">MRDRIPFLATFRRTYGRSLNVSLFTIIISGCILYGHPSLDSYQARMLWGLSSAIGVTVVVCFTIAHRLLRAVKTRLVHSRIPFVAAFMRTYGRSLNISLFSIISCGSILYVNPGLDREHATILWGMFIVGGLTVVVLFYVGYRILAYGIQRLVKKKKGIDFINGLDKGDLFRLFDFMEYERDVSHVRFRNATIFQTLCDLTIIAKKEIRVGNARSSGYFVTDWAKARILKQVQRVFVDKKTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B917</accession>
    <name>A9B917_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07831">
        <property type="protein sequence ID" value="ABX07831"/>
        <property type="gene ID" value="Haur_5204"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5204"/>
    <dbReference type="HOGENOM" id="CLU_067293_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5266-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="268" mass="29149" checksum="03A4E0E63E931DB8" modified="2008-01-15" version="1">MMIVHRVRPFVVFLAAFLAIGSSLWLGDRLDQSASPIEPAYFLPIGLTFAIWGLIFLTGFLYACYQFLPSQQSRPIHAQIGWWMALTNGLTAGWNGTAGHAGTLGTPAFRAEYVVLTVFILAIMLGVLTYVLLLLRKHRSLLAAPDQWFIEFPVLLFFAWLNVAAIANMTAALMALGFTGAPYGAWWAVGMIGIATIVSLTMLHVMPTRFTLWVYAAVIGWGLIGIGINNLDRSLAVVAACSGAIMVVGIGSVLQRSRLHARTLHQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9B1</accession>
    <name>A9B9B1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5298"/>
    <dbReference type="EnsemblBacteria" id="ABX07925">
        <property type="protein sequence ID" value="ABX07925"/>
        <property type="gene ID" value="Haur_5298"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5298"/>
    <dbReference type="HOGENOM" id="CLU_1560841_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5360-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="18675" checksum="3312B2771F0E957A" modified="2008-01-15" version="1">MPTTVQPVQTATVHIPQSKPRAKRMGLYDKVGQTIALGMALALALGIWLVGAKFTLDFLASMGVNLASLSYGQWLIPLAISASELWLWPKGSSIWQRWAVWLGVLLFDVGSSWAGFTEWAGGRYVPLFAGFTMPSEGFPLHGLALVLGLAFAFLPEKIGRWAVSELRTLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUB5</accession>
    <name>A9AUB5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UV damage repair endonuclease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0383"/>
    <dbReference type="EnsemblBacteria" id="ABX03034">
        <property type="protein sequence ID" value="ABX03034"/>
        <property type="gene ID" value="Haur_0383"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0383"/>
    <dbReference type="eggNOG" id="COG4294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017168_0_0_0"/>
    <dbReference type="OMA" id="VFDAHHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-386-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="PTHR31290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0228">DNA excision</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="33717" checksum="A6F7CD37A8529B5B" modified="2008-01-15" version="1">MRYLGLSGRILKRPDLQAPNQQQLSQWVLYLYDVLRYLEQQQIHCYRLPAWPYELLNTWPEAAEQFQLIGNYAQQAQIRLTYHAPSNVLLNSHDPLIRQYALTYLTSAAAYLINLGCDDPVIVVHIGAQYGDRASALAQSVTSLQQLEPAVINVLALEADGRVWSLLDALHIHAQTSIPVIFDWLHHQLYNPAQLNDTEALNYALATWPVQRKPKVHFSSPRTEIRLGQRQQLLLPTWHEHSDLANPFELISLLRLPYQREYDLMLEVKAGDLAIERARNDLQRFAPEISDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF7</accession>
    <name>A9AUF7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0425"/>
    <dbReference type="EnsemblBacteria" id="ABX03076">
        <property type="protein sequence ID" value="ABX03076"/>
        <property type="gene ID" value="Haur_0425"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0425"/>
    <dbReference type="HOGENOM" id="CLU_1658410_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-431-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="18928" checksum="A8ACF67F0851DD40" modified="2008-01-15" version="1">MQQIVIACGINPIGALIELVFWIIGIIMAIWFMVVFKAWAFPRSQWFNRRAPMLKSFIMLMTGATVVILVMTGIYFLAPAIFNYRWGFVRQYHVILLLAICVHDALAMNYWLNQSYAQTLSLDPNQQMQVDPACSHWYQPWVIAFSTNLLLFLCLMPVFRLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ1</accession>
    <name>A9AUJ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1875"/>
    <dbReference type="EnsemblBacteria" id="ABX04518">
        <property type="protein sequence ID" value="ABX04518"/>
        <property type="gene ID" value="Haur_1875"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1875"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_2_0"/>
    <dbReference type="OMA" id="VRITHQN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1904-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="966"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1959"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1990" mass="222902" checksum="48E9F83C00FF9864" modified="2008-01-15" version="1">MNADIEDIYPLSPLQQGLLFHSLYDPDSGAYFEQFTCQLRGILQLDAFRRAWQHVLERHAALRTVFVWEDLAEPLQVVYRAVQLPLDYHDWRELDPQTHTAQLEAYFQTERQRGFDLSQAPLLRASLIQLSDDCYQFVWCNHHLLLDGWSMALLLKEAFSYYSAFCEGRALRLAQTRPYRDYIAWLQKQDQAKAEQFWRANLSPISAPTPLVIERPNYALLGPEQPCEQRIVLDLAATETLQIMARQHKLTINTILQGAWALLLGRYSGERTIVFGSPVSSRPAQLAGSNAMVGLFINTIPVCITIKPQAAVSEWLQALQQQQVEAQQYHYTGLNQLQTWSAVPRGIPLFESILVFENYPLAAWQQSGNATLQLQDVRFIEQTNYPLSIEAVLAPNLVIQVFYDQRRFEPATITRLLEHLQNLLLSFATAPQARLASIDLLTAAERQVMLRDWNTTNVPLPSSIYLHKIVAAHAQATPDAVALRFGQQHLSYGELNRRANQLAAYLRAQGVPPGSLVGLCVERSLELVLGILAILKAGAAYVPLDPRYPLERLHYMLNDSQAQVLLTQHSLSQQIRTEQQRVIYLDHDWPTIAQYPSFELAVPLWPESLVYLIYTSGSTGRPKAVPITHRGLANLAYAQIQAFELDAQQRILQFASLSFDASIFEIVMALWSGATLVLADQETLLPGPSLIELLQQQAITHITVPPSALKVLPEAELPALSTVIVAGEACPAELVARWGLDRRFFNAYGPTEATVWSSLALCDDPNQKPSIGRPIANTQLYILDQYLQPVPVGIAGELYIAGPGLAWGYLNRPELTAQMFVPNPFSAEPGQRLYRSGDLACFLPDGSINHLGRVDHQVKIRGFRIETGEIEQCLCEHPLVHEAVAIARDEPNGQKRLVAYVVATPDNQPSSAELRTFLQTRLPEHMLPAVFVLLASLPLTPNGKLDRHALPAPKTTRHAEQALFDAPQTANQQILAEIWADVLGLAQVGIHDNFFELGGDSIICIQIVARANQAGLRLTPKQVFEQRTIANLATVVGTGPQIQAEQGLVSGAVPLTPIQQWFFAQNLPNFHHWNQSALLEVRQPLDLTLLSQVLYQLHIQHDALRLRFQFGTDGWQQINLDHAATPSISLIDLADLPLEQQSVAITEHANQLQACLNLSTGPVLQVALFNLGADRSGRLLVVAHHLIFDGVSWRIFFEDLATAYQQIAQAKPIQLPAKTSSYKAWAERLVEYSQSTTLQAELTYWNQQIGELPSLPIDFPEALADNSEASQALVTVALDAPTTALLLHEVPKAYHTQINDILLTALARCLSQWSGQAALLIDLESHGREDLFDDLDLSRTIGWFTAIAPLRLTLAESGELGADLQSIKEQLRQVPQHGVGYGILRYLGQQPIQAQPQVGFNYLGQFGYGLSADSPLAWAYESSGADHDPAGLRPHLLEVGGSIVDAQLTIQWMYSTNLYRSTTIEQLAHSLMHELRAIIAHCLQPDVGGYTPSDFPLATLPAADLAQLNAQYRQIDDLYPLTPTQQGMLFHALYEPESTVYFMQISWLFEGKLDLAAFQAAWNHTLNQHTILRSCFVWQGLSQAYQLVHPTVEMPWEYLDWRELEPEQQAINLAGLLEADKTKVFDLSQAPLMRVTLVHLAEHSYHFIWSQHHILLDGWCTNILLKEVFRAYEALVQGLPIPLSQPAIRPYREYIAWLQRQDLAQAEAYWRKRLQGFAKTTPLPPASGAQQAGVDYAVQKLPLDPALTTAIYTLLRQHQLTMNTLLQGLWACVLAHYSGQHDLVFGSTVSGRPVDLAGAENMLGLFINTLPVRVRIQPTLSIIEWLQDVQAQQVEMRQYEYTPVAQVQRWSELPPRQPLFESAVVFENLPMDSSNQGQFNDLTMSNIQSFIQNNFPLTIRGAPSATTFELHVLYDRQRFATTTVLALLGQLEALFKAVQHQPSASLADLAQRLEDFDHHNQKAQAQQSETSSLQKLKHVKRKAIRGQQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM5</accession>
    <name>A9AUM5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1909"/>
    <dbReference type="EnsemblBacteria" id="ABX04552">
        <property type="protein sequence ID" value="ABX04552"/>
        <property type="gene ID" value="Haur_1909"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1909"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_8_0"/>
    <dbReference type="OMA" id="TQMLELC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1938-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="119" mass="13414" checksum="E72DB15913C3A967" modified="2008-01-15" version="1">MVAGKHILIVDDEDSIADMIADALRDEGYTVDVAYDGRRGLELAQRIKPALVLTDVMMPFMDGIKMAELVQREFGATSPPFVFMSAVDCRDQTQLYGQFLFKPFTLDILFDTIETIMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP8</accession>
    <name>A9AUP8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04575">
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        <property type="gene ID" value="Haur_1932"/>
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    <dbReference type="KEGG" id="hau:Haur_1932"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_066192_44_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1961-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="8927" checksum="D0D3151659B990A2" modified="2008-01-15" version="1">MIEGILSNRIRLLRFINGEMTQADLGQRIGVTRQTIAAIEAGKYAPTLEAAFRIAHVFQVPLDEVFQWIPHDGAGMNYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU2</accession>
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        <submittedName>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="316274.Haur_3896"/>
    <dbReference type="EnsemblBacteria" id="ABX06530">
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        <property type="gene ID" value="Haur_3896"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3896"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_7_0"/>
    <dbReference type="OMA" id="FSWYGSR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3938-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
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    <dbReference type="Pfam" id="PF01497">
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    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="28994" checksum="101F5169BD093EB4" modified="2008-01-15" version="1">MWYNSLFDITDDLGRLLHFEHVPQRIVSLVPSLTEYLFWLGLAEQIVGITDYCIVPAEQVAAVSKVRGTKNPNREQIIGLAPDLIIANKEENRQRDIAALEAAGLTIYVSDIESVQQAMLSLAKLAGIVGRAEQADSLIAAIQAELTRKPTTQQRVATAIWRDPWMWVGQATYAADLLACCGASNCLADPTGRYPRLELAEIAALQPDCILLPDEPYAFSQADADELQGLAAQITCCDGQLLTWYGPRIPLALQTYRRLLQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU3</accession>
    <name>A9AUU3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3897</name>
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    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3897"/>
    <dbReference type="EnsemblBacteria" id="ABX06531">
        <property type="protein sequence ID" value="ABX06531"/>
        <property type="gene ID" value="Haur_3897"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3897"/>
    <dbReference type="HOGENOM" id="CLU_1298373_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3939-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="22826" checksum="F344C24913857F75" modified="2008-01-15" version="1">MSFRNTQPSSSQSAPTSPPTTPTPTMQLPELLQASIALAGKPSEPPFGLVRGRGSLKNALIYVAIGAFVSGILILVIGLLIYHFPARLAGQSLLINVLGHTAGFAALISFIAQRQRLSFRQRDEFATALAMAWPPSTLVIGGIFYLLGGFISFVGNLGNLALSLLFMAASLKALRVLFSKPYEETFVSVGYSLLLYNLILSFVTYIVVQLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV26</accession>
    <name>A9AV26_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0453"/>
    <dbReference type="EnsemblBacteria" id="ABX03104">
        <property type="protein sequence ID" value="ABX03104"/>
        <property type="gene ID" value="Haur_0453"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0453"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_4_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-459-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="26095" checksum="1DE3813B8C758081" modified="2008-01-15" version="1">MPTILSVWAHPDDEAFGPVGVLAQAHAAGYRTVIITATHGELGQISPELAINPENLGSVRLEELHQACQAIGVDRSIVWDYPDGGLALANATELRDKIVEVLNAEQPAIVLTFGPDGIYGHPDHIAISMATTQAFAQYLALHPTIEQPRLYYQSVAPNSPRSVNAASSNEYPDPLPATTIIDVSEYADTKRAALEAHATQRHDWQQFLDQADWFNTVYLHRVYPSFGLNDQPETTLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV47</accession>
    <name>A9AV47_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0474"/>
    <dbReference type="EnsemblBacteria" id="ABX03125">
        <property type="protein sequence ID" value="ABX03125"/>
        <property type="gene ID" value="Haur_0474"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0474"/>
    <dbReference type="eggNOG" id="COG2740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147970_1_1_0"/>
    <dbReference type="OMA" id="CVGCQEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-480-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="11853" checksum="3248569859EBD5EE" modified="2008-01-15" version="1">MAAQKQSPRPRHVPQRMCVACRRTESKRQLVRLVRLADQSVVVDPSGKQAGRGAYLCAERPCWTNALKRGALERALRVELSAIDQQALQTIADQFPDAEPAVEAAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVJ9</accession>
    <name>A9AVJ9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase XerD-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2047"/>
    <dbReference type="EnsemblBacteria" id="ABX04690">
        <property type="protein sequence ID" value="ABX04690"/>
        <property type="gene ID" value="Haur_2047"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2047"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2569163_0_0_0"/>
    <dbReference type="OMA" id="TERCTHV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2076-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="81" mass="8990" checksum="3F299A5B5B7A9935" modified="2008-01-15" version="1">MNRTGLCRAFGLSVATCGIQQHATVHTLRHSWATHLLEAGVNLRIIQLWLGHRSPVTTALYTHVSQHAEAIACTTSQRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL4</accession>
    <name>A9AVL4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3982"/>
    <dbReference type="EnsemblBacteria" id="ABX06614">
        <property type="protein sequence ID" value="ABX06614"/>
        <property type="gene ID" value="Haur_3982"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3982"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4024-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="29954" checksum="738BBC777FFA4DCE" modified="2008-01-15" version="1">MKLLDKVIVITGGSRGLGLAMAEAMLSQGAKVVIAGRDQASLEQALAQLKRQSSHVLATTCDVGDLAAIEALRDQTIAQFGKLDVWVNNAGVAGPYGATVAIHPRDYRRVIDTNIFGTYHGSITALKYFQQQGHGKLINLFGRGDTGPVPFQTAYGASKSWVRNFTLALAKEHRNQGIEILGFNPGLMTTDMLTDVQVMAGYESKLEALSTILRMWGNPPSVPAQKAVWLASKATDGRNGLSISLLSPPRLLLGALKEAIRRVRGKPAPALPIKLTTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM6</accession>
    <name>A9AVM6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3994"/>
    <dbReference type="EnsemblBacteria" id="ABX06626">
        <property type="protein sequence ID" value="ABX06626"/>
        <property type="gene ID" value="Haur_3994"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3994"/>
    <dbReference type="HOGENOM" id="CLU_279244_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4036-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732176" evidence="2">
        <location>
            <begin position="30"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="158"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="446"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="694"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="916"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1129" mass="122125" checksum="7C937B81A31E8EB4" modified="2008-01-15" version="1">MSLVLRRFGMIAFMVMFILALAIGSSAKAAPLADDVSIDLGDAPSSNNNFGLMMDAYSGVPAKYPTVFSTVPNGPSHILAKLIHLGPGVSQEDEADSGFDADGPNNIDPSANTPDQDRYDNAFLSPLDINSLPNCQPTQLRYQVTVDPSWTGGTIKLYTNLWFDWDRSGYWGGATFACPNASTTEWSVQNDVNVITGPGTYIFSTSAFLPVNTNSNKPLWMRISLSETPATNDDGRGPANRWKYGETEDYLLTGSDEPTPEPTKTFTPTPVPTRTFTPTPPPTRTFTPTPTNTATATSTNTPPPTRTFTPTPTPSGNDIISDLGDAPDSTNHFSTGMLAYAPATGARYPTVFDPSTGLPEGPLHYDAKQVVLGNLSTFEREADIGPDADVVNNIQPSTNLPNLDKADDAFYLGVPTVNSFIPACQTEALDYQVTVNSVPAGVTRLYVNVWIDWNRSGFWGGSTQCNGGLANEWAVQNQMIPVVSGNYVTPNFLSGIQTSNLGDIWIRITISDSPATNDDGRGPSSGWKYGETEDYLLRYTSNPTPTNTPTHTPTNTPTNTPTPTIATPPPPTPVSDLGDAPDSSNNFAVNMTTYVTGVIARFPTVFGGPAPIGPFHRDARRYHLGRGVTFEKEADISFDMDYTHNISPTLNMNDQDRADDGLVSPRTLQGYKHCVSTRFTYTVTNNTAGPLTVYFNSWWDWNRSGNWGGTLQCPNGLSNEWAVQNQAIVLNPGVNTFTTPAFFPYHPPQRAGIWFRMTVSPTPASAADGRGPTAGWEFGETEDYIFMPDLGDAPDSNNSAGASILAYSPATQGFFPTIFNRVPAALPKGPLHQNLGMPYMLGKSLTAETDADIGLDDDATTNIQTALNRGNYDRADDTFAGGPPTANSFGHCRANTLPYTVRLPNNPAPTGSMVAYVNVWIDWGANGQWGTNYGCVDSLGITRTAREWAVQNQVVNLSGPNVYSLVTPVFYSYQPTLPFKPVWLRITISNTPATAADGRGPTAGWEYGETEDYQLKVLLTHVVSGHVFDSAGLPLVDANVYLYRRGTTGNPAPELVASAQTDEQGFYEVSGEANGDYLIFVEQAGYQSIWYKDAATADQAQPISVDELGVNRIDVTLVPNGEPEPTYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM7</accession>
    <name>A9AVM7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3995"/>
    <dbReference type="EnsemblBacteria" id="ABX06627">
        <property type="protein sequence ID" value="ABX06627"/>
        <property type="gene ID" value="Haur_3995"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3995"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_416636_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4037-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="594"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="658" mass="75003" checksum="180654519D404D84" modified="2008-01-15" version="1">MNQPDLLAYNLATLEKMLAEALRHAREGDVLFLASSPLATCQIIERWYVADTPQGSAELGRAVQALLWWLIERIRPHGERHWLALPWRAYNVLAGFYIEGLRIADLAEAMGVVEQTIYPIRNQAVQSLAKLLLEELQQPSTTLPNHAIIGLYPQLTVAEQTLARMLAFNQQPLAQRWLEHWLELNAIAEPIIQQLADHGLIKSESLALVEKLRPFLQSQISAPERRRWHQQLAELLQPSEPLQSIQHWLQAQAYDQAASLIIAEHQTIVDNLQGRALRELLAQIQAHDIQQPQLWFRLKLVSGDVAMTMNDVQTALGEYQAALAANEPLLKAEAYYKRGKAFRSQSTMEAQAHFNYSIAILERAAPNDPLRYRVCLEQAWMWFQDQRDFEQAQTSLAQAASLIDPLDRGAWAELANARGMFYAHRGEHAEAINQHQAAWLAANEVNHSLLMTHIAHNLGYDYLDLGHYSQALDYFEQSLNLANRTGNRRMQGLCQKSIGACCFWMQEFTLAVEHYLAAYQIFAAMHNHNWQANTCYDLAEAYAELGQSQLMRHYYAEAIQLAQASGLDRLLNDLHGLAENYPGLYPPTIELNERQQRIFDYLKQHPSITNRDYRELTQISPKQAARDLNDLVERNVLVRSGDGRSTSYQLPQSKANEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW8</accession>
    <name>A9AVW8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0558"/>
    <dbReference type="EnsemblBacteria" id="ABX03206">
        <property type="protein sequence ID" value="ABX03206"/>
        <property type="gene ID" value="Haur_0558"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0558"/>
    <dbReference type="HOGENOM" id="CLU_766772_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-567-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005564">
        <property type="entry name" value="Major_capsid_GpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03864">
        <property type="entry name" value="Phage_cap_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="361" mass="39817" checksum="17273F85ABAF4FA2" modified="2008-01-15" version="1">MDIASLLNQARADGTLTRLMRNVLAQFGRPQRRYLGAELLPERMVEENQYTEESIRYRTIVANGGTRYGPAQKKGGDLIGTFDVKLANSDIARELSGRDYDILLRYLGRNASMDAIAALTNWAETTLNLALIEVNEAWRWQAIVDASVIIEGDNAFREPVALTNPAGHRVNVADDWADPTYDPFQDIYAMADLLQSKGYTVGRMFAGTPVLTKLARNPKVAARTSHFVANNGGALELVAGRASLMGVNMALQMDGLPPIERYDLRYNTQNGDVRFLHEQAFVLVALTGRNEELDIPDGEQTLITDTLGYTAIGKPAGHSEPGRVINTEFKTDKPPRIEGQAWQTSFPILAEPEAVAVLKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW05</accession>
    <name>A9AW05_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0595"/>
    <dbReference type="EnsemblBacteria" id="ABX03243">
        <property type="protein sequence ID" value="ABX03243"/>
        <property type="gene ID" value="Haur_0595"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0595"/>
    <dbReference type="eggNOG" id="COG1283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737107_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-604-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015114">
        <property type="term" value="F:phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030147">
        <property type="entry name" value="NptA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="PTHR10010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="PTHR10010:SF46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="391" mass="42515" checksum="39985A9E5E042DF3" modified="2008-01-15" version="1">MSEHQSEQDVGVDSPATPSLLQRNRWLRRLMKFGFVVVGLFFFILALRLLSKGAGGLGPFLTKTLGIENALNTLGFGWLFAYGVLSGSPVAGIALSFLDSKVIDPLQAFTMITGSRLGASFIVLVIGFIYFLRGREKAASLSIGVLALSVTATTYLPALAIGYWLLTDSGLDQVRIALPSAIFDFVEQVFDPIVAWLIRTIDSGIVNIFGTTPATTGVLPATSVVIFVVGVGTLLFAFNLLDKALPQVDAEHNAFGRVGGLIYRPWAMFLLGAFVTSLTLSVSVSLSILVPLSARGFIRRENTLPYIMGANITTFIDTLIASLLIKDPFAFTVVLAEIISITVISLIILVFLYRPYERLILRLLDRVVNDTPMLVTFMVVMVVTPILLLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW77</accession>
    <name>A9AW77_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2087"/>
    <dbReference type="EnsemblBacteria" id="ABX04727">
        <property type="protein sequence ID" value="ABX04727"/>
        <property type="gene ID" value="Haur_2087"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2087"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_9_0"/>
    <dbReference type="OMA" id="PTHQVED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2115-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="24"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="339"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="372"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX04727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="579" mass="64001" checksum="3B5437DCA82C5EC3" modified="2008-01-15" version="1">MQFPLARYRRLLATYLKPQRGRVLGLGCLVFLGIGLQLLNPQIMRRFLDSALAAQPLEQLTKLALLFMGIAFGQQLLALGAVYLSEQIGWTATNALRADLTAHCLHLDSSFHNHKTPGELIERIDGDVTTLANFFTQFIIQLLGNGLLLLGIIVALALEDWRVAVGLIVCVAAAISLLQKMQRVGVPLWGESRQASAELFGFLEERLAATEDIRSSGARNYVMQQLYRQMLVLYRKTRKAELATAWLYNAGQSMFIIASGLGLGIGIYLYQQQQTTIGGVYIITAYIGLLTTPLEQILRQIQEFQKASAGILRIDELRQQRPAIVDGTGPTIPQQALDLRFEQVSFGYNTDTPVLRALSFELPAHQILGVLGRTGSGKTSLIRLLLRLYDPHQGTIRLGGIDIRNTSLADLRRSIGFVSQDVQLFHASVRDNLSFFDHRIADQQLLAALETLGLTNWLNSLEHGLDTLIKPNGLSAGQAQLLAFARILLKDPRLIILDEASSRLDPASEAIVERALDRLLAGRTAIIIAHRLATLQRADAILVLDAGTIREFGPRQALLQNPQSQYSQLLQHGITEVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW81</accession>
    <name>A9AW81_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2091"/>
    <dbReference type="EnsemblBacteria" id="ABX04731">
        <property type="protein sequence ID" value="ABX04731"/>
        <property type="gene ID" value="Haur_2091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2091"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2119-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1830">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041464">
        <property type="entry name" value="TubC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044894">
        <property type="entry name" value="TubC_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18563">
        <property type="entry name" value="TubC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1031"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1145" mass="127974" checksum="CAE1932D28FBFF16" modified="2008-01-15" version="1">MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAPIPRLEDDQPVALSFAQQRLWFLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERHTILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAECYQQLLAAFEAPFDLAIAPSLRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRDLAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERLTNLNQTHGTTMFMSLLAGFFALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLRADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQPERKLDQQPLFQALFALQNMPTGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYAQFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAIALSYAEQAISYQQLAEAADQLVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAYLPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATTILNLDQLPTTKLTQLPTIHPDQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEIWGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLALRLIIFGGEALDLASLAAWYQAYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLIGLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLKQAALTAQRFVPDPWSSTGARLYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQHERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQLDVTLEQASSIAPNNPIQALIAAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELLRVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQKLQQATPEQRQQALASKRQERTVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWI1</accession>
    <name>A9AWI1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4108"/>
    <dbReference type="EnsemblBacteria" id="ABX06740">
        <property type="protein sequence ID" value="ABX06740"/>
        <property type="gene ID" value="Haur_4108"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4108"/>
    <dbReference type="eggNOG" id="ENOG50344S9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1803541_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4154-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="16340" checksum="994C422C21C03E05" modified="2008-01-15" version="1">MRLWRKTVVRATLLFSDSGVMVEAYDEYMFSETSPPLVVGKYREIPAPRGAAVFAIQFTHVITEIFQTLQTFKLQYYLPQQPNSFLEDYLSGPGADADLSLRAVATGADSLNRDQKRVICTLLSKSDPQAWERSREFRQLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN1</accession>
    <name>A9AWN1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4158</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4158"/>
    <dbReference type="EnsemblBacteria" id="ABX06790">
        <property type="protein sequence ID" value="ABX06790"/>
        <property type="gene ID" value="Haur_4158"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4158"/>
    <dbReference type="eggNOG" id="COG2215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030955_0_0_0"/>
    <dbReference type="OMA" id="THTISIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4204-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731682" description="Nickel/cobalt efflux system" evidence="8">
        <location>
            <begin position="24"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="447" mass="47631" checksum="2D0B7DCF856C6F16" modified="2008-01-15" version="1">MKRCLCACWLLLLFASQPQTAQAHSLDQLFQDMRVQIQPTQIVLTVHLIAGPLITPRLWEHLDTDRSQTLDQIEIERWCAEFNRNLELAFDHQALSLTLYEVSEFPTTKADFIGSNATNLTWTVQAALGPIATGEHLLSLKSNNYHDISVVDWSKTRGRAGIVAQDASTMDLHSAQFPIKWPSNFRSDGAIALPTAEPSAPQQPSSSLVARLQTGDSSFGLIAATLGLAFGFGAVHALQPGHGKTLVAAYLVGSRGTIQQATLLGAIVTLTHTASVFALGGLMLLFSAWATPERFIPILTFVSGVLVAGLGLRMLWERLQALRSGNQGHSHGGLFHSHGDGGAGHSHVSNRKLLGLGISGGLVPCPEALVIMIVAATLGRIGLGLAMIVAFSAGLAAVLIGIGIVLVTLGSRLIKTSQPDARWLRWLPIASAGVVTILGIGLMLQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWY2</accession>
    <name>A9AWY2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0735"/>
    <dbReference type="EnsemblBacteria" id="ABX03383">
        <property type="protein sequence ID" value="ABX03383"/>
        <property type="gene ID" value="Haur_0735"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0735"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_3_3_0"/>
    <dbReference type="OMA" id="YGYQMIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-747-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017799">
        <property type="entry name" value="Tscrpt_reg_PadR_acidobac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03433">
        <property type="entry name" value="padR_acidobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="111" mass="12667" checksum="7F10E3DF894EEDDF" modified="2008-01-15" version="1">MFERELLKGSLGLMLMALVEQGPMYGYLIAKEIRALTDDVIDLKEGSLYPALHRLEKEGMIEGFWQRREDGVDRRYYRITAAGQAVLDERRAQWSRFSAAVSKVVSDAPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX99</accession>
    <name>A9AX99_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4187"/>
    <dbReference type="EnsemblBacteria" id="ABX06819">
        <property type="protein sequence ID" value="ABX06819"/>
        <property type="gene ID" value="Haur_4187"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4187"/>
    <dbReference type="eggNOG" id="ENOG502ZGA1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2464815_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4234-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="88" mass="9874" checksum="879B5D697D537731" modified="2008-01-15" version="1">MRKKVARALFNDQPVEQSTPPKLISFGSNRSDQCTLYDAPAKFEQCLGCEYRRGSKGLGILCGHRFGLDPTYINGVLTQIQDDEIRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXA5</accession>
    <name>A9AXA5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recX</name>
        <name evidence="5" type="ordered locus">Haur_4193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
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    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RecX family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABX06825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX06825">
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        <property type="gene ID" value="Haur_4193"/>
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    <dbReference type="eggNOG" id="COG2137">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="term" value="P:regulation of DNA repair"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="Regulatory_RecX"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF02631">
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    </dbReference>
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    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="26215" checksum="CCAC6953FC5625AA" modified="2008-01-15" version="1">MPTGTITMLEIQQRDHERVNLYIDSVFALGISLRTLEQQGLYKGKVLSEADWQAIAKAEEIDKAYNAALVFLAARPRSSQEIRTRLRQREFPDEHIDFALEKLAQLGLVNDEAFARFWVENRQQHRPKGARAIQAELSQKGVKRELISEVLHELTDQDEEQERAFSVARTALRRYANEPTKMAFSRKMAGLLQRRGFGFDTIKPVLDQLWQELQSNGEADETEADDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC0</accession>
    <name>A9AXC0_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4208"/>
    <dbReference type="EnsemblBacteria" id="ABX06840">
        <property type="protein sequence ID" value="ABX06840"/>
        <property type="gene ID" value="Haur_4208"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4208"/>
    <dbReference type="eggNOG" id="ENOG5030T61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2508185_0_0_0"/>
    <dbReference type="OMA" id="RWATIER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4255-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="8977" checksum="FDD58B3D1EC4EBA4" modified="2008-01-15" version="1">MNMIVTSATMPSDAELAALSAAVVSVLAEVVAEPAITVAPNTWQASAKLSRQGLRPARTGVRPRWATIERLRRRAAGGFYGITGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXL6</accession>
    <name>A9AXL6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0782"/>
    <dbReference type="EnsemblBacteria" id="ABX03430">
        <property type="protein sequence ID" value="ABX03430"/>
        <property type="gene ID" value="Haur_0782"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0782"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1473265_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-794-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AhpC/TSA"/>
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        <property type="entry name" value="PXL2A/B/C"/>
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    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
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    <dbReference type="PANTHER" id="PTHR28630">
        <property type="entry name" value="PTHR28630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AhpC-TSA" evidence="1">
        <location>
            <begin position="12"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="20838" checksum="FEB8A97B55993F85" modified="2008-01-15" version="1">MGKMTAVASNPMTDLWVLNETGERVGFESLWQEKPILIFFMRNIGCGICRQTLLNLRDYDQAFKDAGWQIVVLMMGNVELVSRFRSMYNIPFPIYVDQSLQVYDYFEIVEGSWLQVLSPQVLIRQAKLLVGGMELLNGAGSMRRLGGAAAINRAGQIVYHHVANPIYRYPEWSSVLQTLQQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXT9</accession>
    <name>A9AXT9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2265</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2265"/>
    <dbReference type="EnsemblBacteria" id="ABX04905">
        <property type="protein sequence ID" value="ABX04905"/>
        <property type="gene ID" value="Haur_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2265"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_12_1_0"/>
    <dbReference type="OMA" id="YSTTDTK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2293-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="380" mass="40991" checksum="C5FC43B3CB3A6D8D" modified="2008-01-15" version="1">MKSHFTRIVAHVFTVGLMASLISCGSTQVTPTVSQSAQSVSASNADPALVEASKKEADGILIYSIMSEKNWQPVIQGFNAKYPWIKVTTADLGAYEVFERYYTEAAGNARTADFISTTAPDGWINFIDKGEVQSYVSSEDAQIPELGKIAQGVYAASTDPMVFIWNKQLVADPPQTMAELISMIEKDPSAMQDKLVSYDADGEGFGYGLNWFYTKAKGADGWKTLEAIGSSQPKILTSGGKMIDSVLSGESSIGYFVSNITVQPRLEAAQQLLGYSFVPDAQVVAVRGMAVTKHAASPNSAKLLLDYILSAEGQMAFSQGGLTAYRPDIAASAPLHLSQVSQAVGGEQNIIFSRPDKALADPQQRSQFLNQWKQALGRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXX5</accession>
    <name>A9AXX5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 13 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2301"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04941">
        <property type="protein sequence ID" value="ABX04941"/>
        <property type="gene ID" value="Haur_2301"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2301"/>
    <dbReference type="eggNOG" id="COG0296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158008_0_0_0"/>
    <dbReference type="OMA" id="DFNDWEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2329-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9561" checksum="C01E85CC10AEB620" modified="2008-01-15" version="1">MRVTFNIPAPLTAQTITLVGEFNNWSETATPLLRSGEGWSTTMDLPPNHSYQYRYLADGRWLNDWSADRYEPNEFGGANSVVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY6</accession>
    <name>A9AXY6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04952">
        <property type="protein sequence ID" value="ABX04952"/>
        <property type="gene ID" value="Haur_2312"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2312"/>
    <dbReference type="HOGENOM" id="CLU_1114619_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2340-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="28563" checksum="CC9AC4200F749151" modified="2008-01-15" version="1">MLWKDITSNKREYAIPSQGILVIETENDIAEYTYLKSLRFIQEGFYAPSIKIELYFHIPTIKYDTVENVIIQKDSSITGFIDKINNQGYITMLRYLLIATYHALVVPETSKPTHGSRYSYRGQSSNNYYSDSRRSLPRTKGESNRVSIHNWHQSLSKSQHIVVAHKRFIEDGYDAPHDKYLQAKAAGVILELGYTWVQEHTRGGIDSHPNNNQALVTRFETPVSVTSNIRKCLPSASASLQQPKPKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY98</accession>
    <name>A9AY98_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4348"/>
    <dbReference type="EnsemblBacteria" id="ABX06980">
        <property type="protein sequence ID" value="ABX06980"/>
        <property type="gene ID" value="Haur_4348"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4348"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_0_0"/>
    <dbReference type="OMA" id="HAMSHQV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4401-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="12"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="40556" checksum="A63467032A9B7502" modified="2008-01-15" version="1">MQEFFEFRLLPRVLYKSGLVAEMGAELSSLGATKAFIVTDAGLVKSGLVEQVQQALAETVEVVGVYSDVPPNSSVTVVEAAAAQARESGADLLVALGGGSPIDTAKAMRILITEGGNLLDYEGINVLERRLIPMVAIPTTAGTGSEASNFAVIKDEANNVKLSFTSPYLAPELAILDPQVTQSLPAHLAAATGMDTLTHAFETYVSTESEPMSDALALGAVEIVSNYLRDATHHGSTNEEARGQMLIASCMAGIAFTNSYLGAVHALAHATGGHFPLHHGLLNSIFLPHVVAFNASTVPDRYARLARAFGINTGGRPREEVIDDLIAGLRQLASDCGLITQLRDLGIPEDSLPMLAEQAFGDGAVYHNPVAPTVDDLLGILQAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYY9</accession>
    <name>A9AYY9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4397"/>
    <dbReference type="EnsemblBacteria" id="ABX07029">
        <property type="protein sequence ID" value="ABX07029"/>
        <property type="gene ID" value="Haur_4397"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4397"/>
    <dbReference type="HOGENOM" id="CLU_084423_3_0_0"/>
    <dbReference type="OMA" id="DETIWLL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4451-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025449">
        <property type="entry name" value="DUF4194"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13835">
        <property type="entry name" value="DUF4194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="24414" checksum="CD12A851D745E8B4" modified="2008-01-15" version="1">MSLVNFAEEYSQLSSTEQQLFADSVRRLLSDGLIWREDEQDRRIFAWLVRRIDLVRDYLAVAGWELHYAENLHIFHVFHRDGSHRRRFNRETTLWLLLLRLIYAEQYESLNPSLTRYPTTTVSDVYSRYGEFFPGQTIRKKGAFDEALRLFNGLKLVRAPNSKALRANDPDAVIELLPALEVIVPASGIAALAERLAEYQRPNSADEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ07</accession>
    <name>A9AZ07_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4415"/>
    <dbReference type="EnsemblBacteria" id="ABX07047">
        <property type="protein sequence ID" value="ABX07047"/>
        <property type="gene ID" value="Haur_4415"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4415"/>
    <dbReference type="HOGENOM" id="CLU_1576342_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4470-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="20152" checksum="53D7F66380F6EFF2" modified="2008-01-15" version="1">MSFFRQRRSLIVLSLLNIGLLLTTWWLLWRLLGLELTALPSSWRQQAPSWTDGQKVTAFFLLSLGLTLPRMLWQLLLEWNTSYQVEADGLTIRTLGLLQYYPWQALAQLRPNYSYDDYVQRIDVLIAPEFSQTRWYRRWFYRHYYNKVPLYATSGQLVSLLSQIKRHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ14</accession>
    <name>A9AZ14_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4422"/>
    <dbReference type="EnsemblBacteria" id="ABX07054">
        <property type="protein sequence ID" value="ABX07054"/>
        <property type="gene ID" value="Haur_4422"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4422"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_554088_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4477-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="291"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="5">
        <location>
            <begin position="377"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="53518" checksum="FDA691C1794E8B74" modified="2008-01-15" version="1">MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATSYGLVGIALVSLGLLCWLMLLLFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFGWFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLGMAFWRQPATRRSISWLAFAILFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSEAMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQTLALGNPLRLLENAVSPILDSAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLEQEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQRIIECQRVLMESLNQQPVQRLLIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAATLQAAVGQIIAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZG6</accession>
    <name>A9AZG6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2472"/>
    <dbReference type="EnsemblBacteria" id="ABX05110">
        <property type="protein sequence ID" value="ABX05110"/>
        <property type="gene ID" value="Haur_2472"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2472"/>
    <dbReference type="eggNOG" id="COG4132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_6_0"/>
    <dbReference type="OMA" id="LKREWRE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2500-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="76"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="299" mass="32597" checksum="FC0BF1507754BCC9" modified="2008-01-15" version="1">MAEQASERGRGAQWQHLDLRRINWSWLGTVPFFLFACAFLVLPSASLVIGSFQDNEGNFTLQNIADLGQPSILNAYLLSVQVSGVTALLGTLVGGLLAWAMVLGRLPRFVRAFLIPFSGVASNFAGVPLAFAFIATLGRVGFVTVLLKNLGFDLYDQGFNLYSFWGLSATYLYFQIPLVVLILTPAFEALRPQWREAAESLGASGGYYWRSVALPILTPALLSTVVLLFGNAFGAYATAYALTGGSLNIVPIMIGAQIQGDILHNPNLGYALAFGMMVIMTLVLALYSWLQRRSARWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZH1</accession>
    <name>A9AZH1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR system Cms endoribonuclease Csm3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">CRISPR type III A-associated RAMP protein Csm3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRISPR-associated Csm3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2477"/>
    <dbReference type="EnsemblBacteria" id="ABX05115">
        <property type="protein sequence ID" value="ABX05115"/>
        <property type="gene ID" value="Haur_2477"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2477"/>
    <dbReference type="eggNOG" id="COG1337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067743_0_0_0"/>
    <dbReference type="OMA" id="NPVIKDP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2505-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013412">
        <property type="entry name" value="CRISPR-assoc_RAMP_Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02582">
        <property type="entry name" value="cas7_TM1809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="27938" checksum="72A1030E6280EAFD" modified="2008-01-15" version="1">MSDQTPKIKIVGRIFVNFEIHALTGLHIGGAAGTLAIGNVDNPVIRNPFNSEPYVPGSSLRGKMRSQLEKLYGLAQNTSIGRDVSIHSAKTQAEYDNSPVLHIFGIPASDFLTEPIRLIVRDAALSEQTRAAFRDARTDLPYTEVKWEAAIDRVTSAATPRQQERVPAGAIFDGALTFTLYNDQDTKLFNTVIRGLELVEEDYLGGQGARGSGQVAFKNIMIRFQQHEKPVLEKGEIGSLAELRALWAAQGYAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN0</accession>
    <name>A9AZN0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4452"/>
    <dbReference type="EnsemblBacteria" id="ABX07084">
        <property type="protein sequence ID" value="ABX07084"/>
        <property type="gene ID" value="Haur_4452"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4452"/>
    <dbReference type="HOGENOM" id="CLU_2553631_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4507-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="82" mass="8863" checksum="24697A001630EBC4" modified="2008-01-15" version="1">MNQKSVNLLSLLSGFLGTFLGLVIAYQAISSDQLWPNLWGGLGFGLWGLDSLLDKKINPLAKSIILIVGMLCLVIYLIGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN5</accession>
    <name>A9AZN5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4457"/>
    <dbReference type="EnsemblBacteria" id="ABX07089">
        <property type="protein sequence ID" value="ABX07089"/>
        <property type="gene ID" value="Haur_4457"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4457"/>
    <dbReference type="HOGENOM" id="CLU_1260004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4512-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="25104" checksum="B78BE896F827E2AD" modified="2008-01-15" version="1">MTHQQTYINLGYYLSHEGSSCDHNNITTPEFFFTQDEQQPLVLDPICLDKISNVGAATDLLGQKLDAGFEFPYVFTTFELALEFVERFCSKRYQWQIIGIALPKQFVASSLAAVEALYTQPKPALYAMLQAQQAPHPAMQPLGFDILSFDIFCWESYLYRNVLPQKPILLDLNQHQLIEDYSEAVRLTRRIINREISWDGHPISLGNWVPCLIQSLVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP8</accession>
    <name>A9AZP8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formiminotransferase-cyclodeaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4470"/>
    <dbReference type="EnsemblBacteria" id="ABX07102">
        <property type="protein sequence ID" value="ABX07102"/>
        <property type="gene ID" value="Haur_4470"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4470"/>
    <dbReference type="eggNOG" id="COG3404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088419_0_1_0"/>
    <dbReference type="OMA" id="VAMVARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4525-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTCD_C" evidence="2">
        <location>
            <begin position="8"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="22356" checksum="4D97CC7F37337BFC" modified="2008-01-15" version="1">MTLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIRGLMDRSESLRRELQELADADVEAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPLRAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVRSALLNVEINLNTLEDQFYVRETRAEVAKLTATLHDDTEAVMALVNQQLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZQ3</accession>
    <name>A9AZQ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(P)ppGpp synthetase I, SpoT/RelA</fullName>
            <ecNumber evidence="5">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4475"/>
    <dbReference type="EnsemblBacteria" id="ABX07107">
        <property type="protein sequence ID" value="ABX07107"/>
        <property type="gene ID" value="Haur_4475"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4475"/>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012300_3_0_0"/>
    <dbReference type="OMA" id="DWISSPK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4530-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="78"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="417"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="669"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="751" mass="85867" checksum="8FAFEACACC2BC5BD" modified="2008-01-15" version="1">MDLAPHMPSSFNDDATHSESTKYITATPASSPLVHESEALISRMRTYWPLDEFQLIERAWDVAKVAHAPQIRKSGEPYFLHPVQVAHILVDMKLDPESVAAALLHDVVEDTPITLEQIRADFGREVAHIVDGVTKLSKLEAKSIEEAQAITYRKMFIAMADDPRVVLIKLADRLHNMRTLGAMRPDKQQRIARETLEVYAPLAHRLGIWQFKWELEDLSFRYINPEKYSEIGRQLNLRRETRERIVQRVIARLKQILDRDNIKAEVTGRPKHIYSIARKMERKSVSLDQIYDQLAVRVMVNSVDECYRVLGLVHSTWIPIMSEFDDYIAVPKESMYRSLHTTVVIPGEQPCEVQIRTYEMHEVSEYGIAAHWRYKEGFGNKHDQSFETKLAWLRSAINGQRDLDPTEFFETVKEDVLRDQVFVLTPKGKIIDLPKGSTPIDFAYRIHSEVGNRCIGARVNNKPVPLYYQLQHGEIVDVVTSKVPRGPSRDWLEYVKSNGARTHIKRWFRRQENDVNISAGRELIDKELKRLGVRPTMEELIRANAMKNSEDFLAAIGNGDLSPRQAIQRVISDKGAEEEPLAAIPTIAPPSKPVKPGTIIVRGETDVYTRIAHCCNPVYPEAVIGYTTRGHGITVHRMDCHNVLHERNRERLIDVDWGGTTEKQSYPVPIRIEAWDRVGLWRDVTNAIADGNINIQAVQQLDNKHHGRATLLATIRIESIDQLSRILDKLNRVKDVIEARRENTVAGTMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0N9</accession>
    <name>A9B0N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4626"/>
    <dbReference type="EnsemblBacteria" id="ABX07257">
        <property type="protein sequence ID" value="ABX07257"/>
        <property type="gene ID" value="Haur_4626"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4626"/>
    <dbReference type="HOGENOM" id="CLU_1014793_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4683-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="274" mass="32007" checksum="E3203912888ACE00" modified="2008-01-15" version="1">MLRLFLLEQHDSVLRQVELQHVLEQADQMRQALRLQGYTALGPALQTWDTYAQRVLYQPIAHVFDPKLGPEYRVHQIEARLVAEVILAIDAQQRYNLAGIYDQLYEQGLEPLAAPLIPVLPLVGVEPRVQAYIPVLPLGARALWPRHTWWVRKLGWQRPVPELGQQLTWRDQWQHTWPPFLRLQLAALIIILLLSMPWAMLQWWLGAEPQILLFKSFEIFTALRWFGMIGSMLLGVVIWRQRGSAIQAWNRFWATTPTPPLLIIELESEKQREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0P6</accession>
    <name>A9B0P6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1118"/>
    <dbReference type="EnsemblBacteria" id="ABX03766">
        <property type="protein sequence ID" value="ABX03766"/>
        <property type="gene ID" value="Haur_1118"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1118"/>
    <dbReference type="HOGENOM" id="CLU_1330418_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="22943" checksum="FBA881718043BBEF" modified="2008-01-15" version="1">MFIGMYLAIWLALAGAIWWSIRSKNSIGRMQHLLGISLIEPIITVIMLIGMYPVLLEWAWQENMISIASYQLINSNDVLNSVLATVSVGLALLPLLLLFDEQAVVRSVAWQAGLIGLFRWGCLLGLGFLLSADLHPWINTFLVVGYLIMIALTIYLLNAKLRGRLDQAGSPLPVETEQLFQGQPIVYVDPNLQPMIMIDPPKDEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U1</accession>
    <name>A9B0U1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1163"/>
    <dbReference type="EnsemblBacteria" id="ABX03811">
        <property type="protein sequence ID" value="ABX03811"/>
        <property type="gene ID" value="Haur_1163"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1163"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_395749_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1185-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="262"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="696" mass="78352" checksum="AF93351681C22D1F" modified="2008-01-15" version="1">MLFGTIAEYLVALGMPSSARTYLIITTILVLSLIWIETSHWAHRTMTMMELAGAALLLIKIFAVSTTMLTLALLPFPQLRTVIASSLAIMGLLTLYRELRRRLRAGDRSPSSYTGGVLVVIQFLCMVLLTVSGIAIILELLLVPARILDSDTRFIDAIKNWVELLATLCVLLTMYYLGFYLARRLLKSGSFSWIDPPNWRTLLPHLKYSLMPRWGIPPLAESDLADTVRMAYIEHIVGSKAPRDVAKAAKIEPVAHPQRGFTFAVIGDPGEGDESQIAPPIVPEQSALAQQGPANPAYPTFTILSSDIVYPAGELMDYERTLYRPYASDSSTSPLIYGLAGNHDWYNDLKGLMLNFGYAAAHVESRDPQLQQWAKALKTGPWARYGYPWGQLRWNEVQSLRQRYGLTRLGGDLNEPRTHQRLPFFELSFDPVPFVLLAVDTGCIGSVDPIQLQWLETCLLTAFNQQKIIAVVLSEPLYVNGAFADHPGMRQLYELLRRYETHVVIGGDTHAFQHYEARYITLRGTQHIAHHLVNGGGGAYLSKPVDLHWHTPSGMTPLESRFVYRDDEQDIVDQVMLREVFPTAQQLRAKFNGKIELDDQMWGLRRWLVGQEPTILNRGYTNALNHDRSPLLQSLVTFNMDETLNGWRLRITPWFTTGPDNQLEPQEPIDILAPNRANERVVTRDLVPSPASILAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0U5</accession>
    <name>A9B0U5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1167</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1167"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03815">
        <property type="protein sequence ID" value="ABX03815"/>
        <property type="gene ID" value="Haur_1167"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1167"/>
    <dbReference type="eggNOG" id="COG3858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037415_2_0_0"/>
    <dbReference type="OMA" id="WYEAHDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1189-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="89"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX03815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="418" mass="46743" checksum="97776454CCD35617" modified="2008-01-15" version="1">MFRHLFRGVLAIGILVWIVFLWQFIDLRIKHSRAADAAAQALLPRATSTALPVPTFVAPTLQPLPNTVADGQGGSELPASANDVRGVHPKTGRYVAAWLPTSFDAEAARATFEANKDILDEVSPFWYGVRPDGTLIADVGSRDAELVQIAKENNVLIIPTVHNIEDLEAASVVLATPESRTNHINIIMDEVRTYGYDGIDIDYESLALDYEDEFTAFMTELGAALHAEDKLLTVAVHAHTGRPDYQNYADLGKVVDRLRIMTYDYSWRGSEPGPIAPMFWVKAVAEYAKTQVDPSKIQIGISFYAYDWPGNGGFGVARTYTEVEEIKATYQPQIRLVEEDGGQQIQESTFNYAGRTVWFSNYRSLTAKMEMVRENDLAGIAIWRLGSEDPQNWTYIRESLKQDPLIVQRSINRYLPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B199</accession>
    <name>A9B199_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4655"/>
    <dbReference type="EnsemblBacteria" id="ABX07286">
        <property type="protein sequence ID" value="ABX07286"/>
        <property type="gene ID" value="Haur_4655"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4655"/>
    <dbReference type="eggNOG" id="ENOG5033U38">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1325261_0_0_0"/>
    <dbReference type="OMA" id="HQGEGGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4712-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="23700" checksum="7216258A9F270EBE" modified="2008-01-15" version="1">MSDGMPTHELDLVVGSMITVSPEDDRAMFEEEKAWVEDVQDLLREEGVEVDLLSMPGAEVYNGGIATFADLYNLRRLAAHSEKGSDLDNLPANLEDDEVDPVLANIWEGESQTKYPHLINHQGEGGYYLPVDFAEPIWLSYEGEEADEEEWEEGSEDVVSFGSSVALSRELTELEGHVRNLRGAEGQAAHQALHELRAAAQHSIENNLPLILW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A3</accession>
    <name>A9B1A3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_4659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4659"/>
    <dbReference type="EnsemblBacteria" id="ABX07290">
        <property type="protein sequence ID" value="ABX07290"/>
        <property type="gene ID" value="Haur_4659"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4659"/>
    <dbReference type="eggNOG" id="COG1232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009629_3_0_0"/>
    <dbReference type="OMA" id="WFDQWFG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4716-MON"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="476" mass="51992" checksum="7FA8C00475D117EC" modified="2008-01-15" version="1">MDVADQPRIAIIGGGIAGLSTAWYLQQQGLTNIQLFERDQRLGGKLRTSHVALPDGAGELLVEAGPDAFISQKPWGLQLARELGLEDQLISTEPARHKVFVLHRGKPEPLPDGINLVVPTEFWPLLRTPILSLPGKLRMLLDLVLPARQSNTDESLADFVRRRFGAEALDKLAEPLMAGIHNAESDRQSLEATFPRFIEAERSHGSVIRGILAAKLKAGKPKGQQLSPFISLRGGIEQLITALVEQLNVEIRTNCGVQALRYDPTNASAYQLTLDDGTKIDADAVVLAVPSFVAAELVAPWAEALAERLKAIRYVSTGTVSLAFRRSETNMAFDSYGLVIPRSEYRLINAVTINSRKFAGRAPADYMLLRAFVGGSKHPEVLRLDDQALTQLVRDQLKSIFGLTAEPIWSGVARWNEANPQYDVGHFQRMDQLEALCPEGLLLCGSGFRGVGIPDCVRQGQATAQAISQLFALANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B2</accession>
    <name>A9B1B2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4668"/>
    <dbReference type="EnsemblBacteria" id="ABX07299">
        <property type="protein sequence ID" value="ABX07299"/>
        <property type="gene ID" value="Haur_4668"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4668"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051050_1_0_0"/>
    <dbReference type="OMA" id="PNFLHQG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4725-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="21"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="28806" checksum="ADF5938E42448B85" modified="2008-01-15" version="1">MQINVTYIGTATVLLEIDGLRILTDPVFDPAGSARVYQVRPQVEFALYKQTPAALPASEIGAIDLVLLSHDDHYDNLDDAGRALLPNAGHVLTTESGRQRLQQQGATNVQGLAEWQSITVNTPQDLPLTITAVPAQHGPVELLPIIGEVIGFVLEYPAFEHGPIYISGDTVLFDGITAIAERYAIGTVFLHVGAAQFAPTGPTLFTFDATQAYQAAQLLKPQSLIPIHFDGWQHFSQGQAEIDQAFAGSDIQPRWLDLGVETKLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L4</accession>
    <name>A9B1L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1251"/>
    <dbReference type="EnsemblBacteria" id="ABX03899">
        <property type="protein sequence ID" value="ABX03899"/>
        <property type="gene ID" value="Haur_1251"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1251"/>
    <dbReference type="eggNOG" id="COG4929">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105410_0_0_0"/>
    <dbReference type="OMA" id="SIMQGDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1273-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025833">
        <property type="entry name" value="GDYXXLXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14345">
        <property type="entry name" value="GDYXXLXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="18232" checksum="2CAF108F19D4AE9B" modified="2008-01-15" version="1">MSIRYGLIILSLVACLGLVNFSVVQREAIINTGRVVYLELMPVDPRSLLQGDYMELYYNTFPRGYNRNIPSRGTVVLTIDQQNIGTFSHFETSEQALAANQQRLKYRSRGYDVQLAANTFFFQEGTGERFNQARYAELHINEAGEMALVGLRDKDLNLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R6</accession>
    <name>A9B1R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2720"/>
    <dbReference type="EnsemblBacteria" id="ABX05358">
        <property type="protein sequence ID" value="ABX05358"/>
        <property type="gene ID" value="Haur_2720"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2720"/>
    <dbReference type="HOGENOM" id="CLU_2682781_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2751-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030888">
        <property type="entry name" value="Put_ccm"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04391">
        <property type="entry name" value="CcmD_alt_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="74" mass="8190" checksum="ADD6E70EC39D3127" modified="2008-01-15" version="1">MNGLTDPGLAMYVAAAVTLVVWLGIFAYLLKIDRQAKALRQALQERQANPANQTNNAPIRPERVSPERKETSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1U1</accession>
    <name>A9B1U1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="13">PRA-CH</shortName>
                <ecNumber evidence="13">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="13">PRA-PH</shortName>
                <ecNumber evidence="13">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">hisI</name>
        <name evidence="13" type="synonym">hisIE</name>
        <name evidence="15" type="ordered locus">Haur_2745</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="13"/>
    <dbReference type="EC" id="3.6.1.31" evidence="13"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2745"/>
    <dbReference type="EnsemblBacteria" id="ABX05383">
        <property type="protein sequence ID" value="ABX05383"/>
        <property type="gene ID" value="Haur_2745"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2745"/>
    <dbReference type="eggNOG" id="COG0139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_3_1_0"/>
    <dbReference type="OMA" id="ERSCFHQ"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 13 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="14">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="13">
        <location>
            <begin position="117"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ABX05383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="23633" checksum="FA9A949E76731D37" modified="2008-01-15" version="1">MVELTYDSQGLIPAVVQHARSGEVLMVGYMNAEALAKTQTSGLVTFWSRSRQQLWTKGETSGNVLKFIAARTDCDNDALLILAEPTGPTCHTGSRSCFHTTLDGTKREGSAVPLAFVSQLFEFLREREQTRPIGSYTTYLLEKGVDKIGKKIGEESAEVIIAAKNGNADELRNEASDLIYHLFVLLLNQGVSPEDVWFTLRERHGRQREEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2I7</accession>
    <name>A9B2I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1387"/>
    <dbReference type="EnsemblBacteria" id="ABX04032">
        <property type="protein sequence ID" value="ABX04032"/>
        <property type="gene ID" value="Haur_1387"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1387"/>
    <dbReference type="HOGENOM" id="CLU_1747133_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1408-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="16491" checksum="84F0F409999D4A68" modified="2008-01-15" version="1">MDSLLIGAVVWLIGLTIVVMVGAWMFARGYLSVVRENVSLKAELHAVRDAAKRELAALSAQFDLALSALRREVINARERWTIDAYALMDAQLYIQALEDTCHHHQIPLPKKPRRAGLDRPTTSPRTDDQHTGLDPIDELLSPLGQGASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L0</accession>
    <name>A9B2L0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2823</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2823"/>
    <dbReference type="EnsemblBacteria" id="ABX05461">
        <property type="protein sequence ID" value="ABX05461"/>
        <property type="gene ID" value="Haur_2823"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2823"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_0_0"/>
    <dbReference type="OMA" id="WVLASHQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2854-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="43332" checksum="8AD32F376EBE5883" modified="2008-01-15" version="1">MRRSPFYGWWIVSMLGFTEMTSWGVIYYAFSVLLTPMQRELGWSQAHFTGGFSLALFISGIVALPVGRWLDQHGARGLMTLGSCLAAILVVAWANVQSLLAWYLIWAGLGLAMAAILYEPAFAVVATWFQQKRQHALTILTVGGGLASVVYVPLVTRLLGTLNWREVLLWLAAILAVLTIPLHGLVLRGKPADLGLLPDGGSLAVATVTPNPTIQPSMSLGNAIRASSFWWLALAFGLTTMATFTLGVHLISAIQAQGYAPEIQALAVALLGGSQIPSRIVIGSVGRRWPQVQLAWMLCLLQSAAFAIFLFVPNVTGLLLFACLFGAGSGALTPTRAALVADVFGTAQYASISGALALLTTTARALAPVLASLLVGLLHSYQPLFGLLLLMCLISAAAIYLIRGASNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Z0</accession>
    <name>A9B2Z0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphoglucomutase</fullName>
            <ecNumber evidence="9">5.4.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4823</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4823"/>
    <dbReference type="EnsemblBacteria" id="ABX07453">
        <property type="protein sequence ID" value="ABX07453"/>
        <property type="gene ID" value="Haur_4823"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4823"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_7_1_0"/>
    <dbReference type="OMA" id="DTRFMSE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4882-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="6">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="7">
        <location>
            <begin position="162"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="8">
        <location>
            <begin position="271"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="5">
        <location>
            <begin position="406"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="471" mass="51626" checksum="46B12268CA63A92B" modified="2008-01-15" version="1">MASAIKFGTDGWRAAIAEEYTFDNVRIVTQAVADYLHEAGLAPRGLVVGYDTRFGSERFAAATAEVLAANGIHVYLTEKATPTPVVCWSILCKKAGGASIITASHNPPSDNGYKYKPEYAGSASPEVIARLEDRLEKAPVKRMALREAEKQGLVERINGTPDYVAQIKQMVDLEAIKREGWTIINDAMYGAGAGFLPLLLDGGQTKVVPINDTRNPLFPGMRSPEPIDDNLTKLKNVVKQSGAFAGLAYDGDADRVGLVDEKGKFVDQLRVFGLLTYYLLEVKGWRGPIVKSLSTTSMVNRLAELYNVPIYETPVGFKHIGPKMIESNAIIGGEESGGFAFAKHLPERDGILSSLLLLDLFLKRGKTPSETMEELFSKVGPHFYDRLDITYPAEQRDTILKRVDSARPDALAGLTVNSITTQGGYKYHLQDGSWLLIRFSGTEPLLRIYTETRSPELVEKLLAEGRVIAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Z2</accession>
    <name>A9B2Z2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4825"/>
    <dbReference type="EnsemblBacteria" id="ABX07455">
        <property type="protein sequence ID" value="ABX07455"/>
        <property type="gene ID" value="Haur_4825"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4825"/>
    <dbReference type="eggNOG" id="COG1832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112567_0_0_0"/>
    <dbReference type="OMA" id="MVMDRCP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4884-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="130" mass="14032" checksum="0190B506FB3A25CE" modified="2008-01-15" version="1">MSDIKQLLSNAKTIAVVGLSNKPDRASYGVAEYMQRAGYKIIPVNPVLKEPVLGEQPVASLSDIKEPIDIVDIFRRAEDVPPVVEEAIAVGAKAIWMQLGIVNHEAAAAAEAAGLEVVMDKCIKVEHMQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B338</accession>
    <name>A9B338_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4173 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4871"/>
    <dbReference type="EnsemblBacteria" id="ABX07501">
        <property type="protein sequence ID" value="ABX07501"/>
        <property type="gene ID" value="Haur_4871"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4871"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025121_0_1_0"/>
    <dbReference type="OMA" id="YALTYWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4931-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025231">
        <property type="entry name" value="DUF4173"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13777">
        <property type="entry name" value="DUF4173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4173" evidence="2">
        <location>
            <begin position="243"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="493" mass="54314" checksum="F097C2F88D5AAFFC" modified="2008-01-15" version="1">MTRQQQLALYLLPVAFGLALIADLLGLFHQLWGINFVLWTLLSSGAIVGLAFKQAQALPKETWLWLVVANIASLGFVLRDNGAILFWLGLCWVLAWMLIFSQPYRAHWQLASIRGWIVSGVVAGFGAAFGSFAASIHLPLRVGNFTSAKLRPILIGLGLALPLLCVFGGLFASADAVFENIFADLFNWNLDWLFEHAFVVLFSTWAILGCGWILFAAPKPDIALSQRPSLFNIGKIEVGIILGLLNALFGLFVLIQIRYLFGGEQQIAEGISYADYARRGFFELVTVALLVLPTLLVGSWLSEQRTEAQPLFRILALVLLVQVGVVLASAVSRMLLYIDAYGLTESRIQATALMIWIVLVALWFVATVLRQRGQYFANGALVAAMLVLIGLVLLNPSNLIVRYNASHRGVASFDGYYIGSLADDADAVPAIIEVLPSLPAEQNCQIATLLLDNWQENNDDWRSANLSRSNARQAVLQNERMLTDMSCPIDRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B397</accession>
    <name>A9B397_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1416"/>
    <dbReference type="EnsemblBacteria" id="ABX04060">
        <property type="protein sequence ID" value="ABX04060"/>
        <property type="gene ID" value="Haur_1416"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1416"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_2_0"/>
    <dbReference type="OMA" id="HRHDDFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1438-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="179"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="32793" checksum="31F9BB0C267D25A6" modified="2008-01-15" version="1">MSNKHQIEHIQLEHNALAPMFIAKLEPHHIPNVVNLPHRHSFHELLWIKAGTGRHWVDQQSYPLQAHTLALVAQGQVHVFEQAEALNGYYLRYDQAFLPNQSDEQQPSFRANGGLQLSAADSKIIDSLFELLAHEYQREDCLAKYHSLRHLLLTLLWQSQRLSQAADQPPQSANYAIYRQFLALLEQAFQQHHDIHYYADQLNLSKTQLAQIISQHSGQPPKRIILKRILLEAQRYLQFTTMPIQQLAQSLGFHDPFHFSKFFKQELGISPRRYREQSFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L4</accession>
    <name>A9B3L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ABX05586"/>
        <property type="gene ID" value="Haur_2948"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20622" checksum="618EF4CC1A6CE9C1" modified="2008-01-15" version="1">MTIAFEIRPTQAHEEWAVAQLFEGLHYYNTSLDHYFSLSPDWREALHTFLIDQALNQRGITMLAWHGSTPIGLLMLAGQQGSALFKHRNWAELLALYVVQEVRGLGVAQSLLNLAQAWASAQGYQRIQLYVTASNHRAKRFYQAQGWQCVQEIWRLSLDQGQQLADHAEHMNVCLSSQRE</sequence>
</entry>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2963"/>
    <dbReference type="EnsemblBacteria" id="ABX05601">
        <property type="protein sequence ID" value="ABX05601"/>
        <property type="gene ID" value="Haur_2963"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2963"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_107144_0_1_0"/>
    <dbReference type="OMA" id="YGLTIMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2995-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="15572" checksum="48E352D3A263F11C" modified="2008-01-15" version="1">MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRGPQGGHQLARPPQAISLLDAILVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLSEMTIADLCQRKHQQLDSPMYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3R6</accession>
    <name>A9B3R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3000</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3000"/>
    <dbReference type="EnsemblBacteria" id="ABX05638">
        <property type="protein sequence ID" value="ABX05638"/>
        <property type="gene ID" value="Haur_3000"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3000"/>
    <dbReference type="HOGENOM" id="CLU_965665_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3032-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="148"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="288" mass="30333" checksum="A0DAE7F7B9F01817" modified="2008-01-15" version="1">MVFGLTALAVVAYSGLSLLFKALASRTRPAQMVYASSVIATICGLIYFIASGESWSWPAAILAFLAGVTFYFATIARAKALEHSPASLVFAISNLDLVVAGVIILLLPAAWNMLQIGSVTINLPSQAGNPTLGNLLACVLTAVAVLIGAQVKGSEKLSNATYVCLGLLVVSSFAAVTYARNFGAQIGLLMFVDFAAGVIPGLHLTPQVRRHEWGWGAVVGLITFGGFVAMMHAQAMSDAATLPFVLLAINLKTPITAIIAVPLFREQLTARKIIAISLATLALFIWQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T7</accession>
    <name>A9B3T7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger SWIM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3437</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3437"/>
    <dbReference type="EnsemblBacteria" id="ABX06073">
        <property type="protein sequence ID" value="ABX06073"/>
        <property type="gene ID" value="Haur_3437"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3437"/>
    <dbReference type="eggNOG" id="COG4715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129107_0_0_0"/>
    <dbReference type="OMA" id="HIAAVEC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3474-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="16024" checksum="B5F3529FB17622E7" modified="2008-01-15" version="1">MDFPVISDAQIQAMAGERSFERGLEYFESGMVESVLQRGNMIQAVVCGSEDYLYDVAVHTKNAEQISTQCTCPYDYGPICKHSVAVLLFLLYCPEQVVQRPPIRATLDELDDSQIRSLLLDVAEQHPEITTLVEQHIERLGF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-02-09" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B488</accession>
    <name>NUON2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit N 2</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit N 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit N 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoN2</name>
        <name type="ordered locus">Haur_4991</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B488"/>
    <dbReference type="SMR" id="A9B488"/>
    <dbReference type="STRING" id="316274.Haur_4991"/>
    <dbReference type="EnsemblBacteria" id="ABX07621">
        <property type="protein sequence ID" value="ABX07621"/>
        <property type="gene ID" value="Haur_4991"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4991"/>
    <dbReference type="eggNOG" id="COG1007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_1_3_0"/>
    <dbReference type="OMA" id="YYLQWTA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00445">
        <property type="entry name" value="NDH1_NuoN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010096">
        <property type="entry name" value="NADH-Q_OxRdtase_suN/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01770">
        <property type="entry name" value="NDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000391163" description="NADH-quinone oxidoreductase subunit N 2">
        <location>
            <begin position="1"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00445"/>
        </source>
    </evidence>
    <sequence length="539" mass="57586" checksum="5D826568568881F3" modified="2008-01-15" version="1">MNFQIADFTRLIPEFLLLAIAAMVLLGDVLTRWSKGKEALNDRTEEAISMTLMGLGLAFVMVLIQGGFFSWMQFGDWKFYDFSIFQNLRSSGLDGSILGGAFVVDPLTHIGRLVFIGAAFVTVILTSKAKPSNNPAEFYALILFATLGMIFMTAGGELIMIYLGIELTSIPLYVLAGYFRRNPVSTEAGAKYYIFGALSSAILLFGMSLLLGLTLMNGQTMTTTPTSLRSVATAVELAFANPEGPSQGVAILALLFILAGMAYKVAIVPFHAWSPDVYQGAPTSMTAFISTASKTAGFFLLYRVLVTGFGAPSILGTAAIGTSTSFGGWTSLIAILAALTMLVGNLAALPQTNAKRMLAYSSIAQAGFLMLGLVGTQRDSGISLLMYLIAYTVTNLSAFGILALVEDAVGGTDFSNLNGLGRRAPGLALLLTVAILSLAGIPPLSGFFVKFYVFIAAWQEGAKWLVIFAVSNTVISLYYYLRFLKAVYFAPAETDEPIKVGFGPGIVMTAITLLIFGLGIVPTWLYGVLEQATIRIAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C6</accession>
    <name>A9B4C6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0031"/>
    <dbReference type="EnsemblBacteria" id="ABX02683">
        <property type="protein sequence ID" value="ABX02683"/>
        <property type="gene ID" value="Haur_0031"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0031"/>
    <dbReference type="eggNOG" id="ENOG502ZC42">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076890_0_0_0"/>
    <dbReference type="OMA" id="PHFVGMH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-31-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="36118" checksum="7DA27B26D352CFCD" modified="2008-01-15" version="1">MTTTAQFPEARRTTSGAGAILRQFWATSKGMTIFFLLSCFFLVLAIAGVTVDPREVLGQPVWMKSLKFAVSFVVYAPTVLWMFSYVKLRPRLMRFVMDACAAALSIEIVLFITQAVRGQPMHFNVATPIDETLWSIMGTTITVFYLINIVGFVVFLRQKPIADRVFMLSLKLGMGLMLLGFGLGFLMTNPSPAQMEVLQAGGSVPAIGAHTVGAADGGRGIAILGWSSEHGDLRIAHFVGIHGAQVLALIGWLLYNAKQRFNDKQRLALTWGAAVAYLGLVASVTVQALRGQALLQPDATTWISWIGLVVGSVLFTSVVVNQGSVARVQGSGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I9</accession>
    <name>A9B4I9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1510"/>
    <dbReference type="EnsemblBacteria" id="ABX04154">
        <property type="protein sequence ID" value="ABX04154"/>
        <property type="gene ID" value="Haur_1510"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1510"/>
    <dbReference type="eggNOG" id="COG4312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066898_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1532-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010296">
        <property type="entry name" value="DUF899_thioredox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05988">
        <property type="entry name" value="DUF899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="30090" checksum="0DB9A4C6456E1AE0" modified="2008-01-15" version="1">MTKSEPQPIAFVTDSASAMPNIVDRANFQATVDRLRSREKAHTREADAIAAERRRLPMVELDPLTPLVGKNGTVPLIEAFEGRQQLMVAYMMWHEGKTAAEQCPGCTMVISHANQLGYLHTRDVTLAVLCQGPFEPSNRYREFMGWTMPWYSVPEASVETLIAGRHFGMWACYLRKGDRVFETYWTTDRGCELMGSSFAMLDMTVYGRQEVWQQVPAGWPQPFDNTMCLPNTLQNDNPLAHRPIAQWSRVAEGHADNLQPAANEAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4J8</accession>
    <name>A9B4J8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1519"/>
    <dbReference type="EnsemblBacteria" id="ABX04163">
        <property type="protein sequence ID" value="ABX04163"/>
        <property type="gene ID" value="Haur_1519"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1519"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076095_0_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1543-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="24142" checksum="83DA5BDBB637D1B8" modified="2008-01-15" version="1">MNNRSYNQYCGLAYALELLGERWTILLIRELVAGPRRFKDLLNGLPGISTNLLTERLKHLELHGMIVRQVLAPPAGSTVYGLTDLGRGLEPTLIELGKWGSQFVPASSEHVHILTIGSYALTLKTFFRPELAQFRASYQWHVDGELLSITIDHGQLHIQQGPSQQPDAIIHTTIELYLQLLQGAISPQQAVAQGLMHIQGDLAALDRFLACCAINTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4S5</accession>
    <name>A9B4S5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3010"/>
    <dbReference type="EnsemblBacteria" id="ABX05648">
        <property type="protein sequence ID" value="ABX05648"/>
        <property type="gene ID" value="Haur_3010"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3010"/>
    <dbReference type="eggNOG" id="ENOG5031Y5Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065106_0_0_0"/>
    <dbReference type="OMA" id="WHGVLYS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3042-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="40495" checksum="5954B3D519CD7CFD" modified="2008-01-15" version="1">MASIGRIGRNVSSLPRPDEYPPSSITFDFMSMVFAAWWLIGLFADGAAHAANAVDTFFTPWHLILYSGFLAVALWIGGLQLRNMYKGYTLWRALPRGYLLALVGIILFAIAAPLDFIWHDVFGFELRLDALLSPPHLMLISGAMLFGTAPLRTAWIRMQQGEKLAGWRGGLAPMVMSLFFLMVTTAFMTQYAHPLASPKWLSLPYVGAPEIEMYRADLWGIASAHISTFVLISILLLSLRFWPLPFGSITLLVGGSMFLLWAMRASRVMQYWPVLVWAVVIGLAADCAMHYWKIDRHNRLGIRLLCSLLPAGFFLGYYLIIMAGPGLTWITHMWTGMIFEVAIVGLILSFLVAPPYEAPSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4U2</accession>
    <name>A9B4U2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tilS</name>
        <name evidence="9" type="ordered locus">Haur_3027</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3027"/>
    <dbReference type="EnsemblBacteria" id="ABX05665">
        <property type="protein sequence ID" value="ABX05665"/>
        <property type="gene ID" value="Haur_3027"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3027"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_0_1_0"/>
    <dbReference type="OMA" id="QQYGMNA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="404"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="28"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="486" mass="54889" checksum="3FDE1E767EED7DC7" modified="2008-01-15" version="1">MSQLLDIETTLIRDGRLASAACLVVAVSGGPDSLALLHRLTALATPYGWRLHVAHLDHGLRGEQSAAEAAFVAEIAADWGLTATIELRDVDQVAKQYHVGLPAAARATRYRFLAEVALQQQADAVVLGHQSDDQAETVLLHVLRGTGPSGLSAMRPRTEWVGWRVTAGMPHQAVGPALIRPMLNITRDEIEAYCDEQQLEPRRDPTNNSLEYTRGRIRHQLLPLLGEYNAKVVSALARTARLAAIETDYMQSELDRQWQHLIEFEPGAITFHREQWNHMHPALQRHAIRRAVYLLRPERDELTSSQLDHALSAMNSLQLFCQMPHNLVLHRKPHGWTMTVATTMQPTNDEPQLSIDEWPLNQQGMTPLPDERWRVIMELMPSRPEYNLSRWQGLLDANAIQGRLMLRQRRPGDRMRPAGGIGSRRIQDIMVDMRLPRELRAQWPLFVDDVGILWIPGLLMAEHAHPTPETTNFLLITLEDTHADAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B542</accession>
    <name>A9B542_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA binding domain, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3543"/>
    <dbReference type="EnsemblBacteria" id="ABX06179">
        <property type="protein sequence ID" value="ABX06179"/>
        <property type="gene ID" value="Haur_3543"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3543"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324471_0_0_0"/>
    <dbReference type="OMA" id="WRRVGQQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3580-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="207" mass="23334" checksum="DD726CABC51B1F96" modified="2008-01-15" version="1">MTELSIDIDPEWLSLSEASDLLGAAPSTVRRWGDAGLVPTKRTLGGHRRFQRAAVERMVNQQQPDHTPVPELGQTRHWHLDTRELMGQGWHARFDTNPTTERMRGLGQRLFGMLMQYVNSNELDERILAEAKAVGATYGREAREMGVSMHDTVEAFLFFRRAFAQLAKPQSVRPIDVATVVELRTRLDLFMDATLLGTIEGFEQAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D4</accession>
    <name>A9B5D4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Caa(3)-type oxidase, subunit IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0107"/>
    <dbReference type="EnsemblBacteria" id="ABX02759">
        <property type="protein sequence ID" value="ABX02759"/>
        <property type="gene ID" value="Haur_0107"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0107"/>
    <dbReference type="eggNOG" id="ENOG5030QD4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2131648_0_0_0"/>
    <dbReference type="OMA" id="QHLIAKW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-108-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="110" mass="12550" checksum="F82B3AC87EBEA02C" modified="2008-01-15" version="1">MAHGHDEHAPTEHEAHHSHAKLYVIIFFVLLVMTGIEIALPIINKAEIMAKQLEVALLLGLMTIKGAIVMMFYMHLKGDRRMFGTLFVFPIVCVLLMMLGFFALFQPELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F5</accession>
    <name>A9B5F5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol kinase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0128"/>
    <dbReference type="EnsemblBacteria" id="ABX02780">
        <property type="protein sequence ID" value="ABX02780"/>
        <property type="gene ID" value="Haur_0128"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0128"/>
    <dbReference type="eggNOG" id="COG1597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045532_1_0_0"/>
    <dbReference type="OMA" id="VNSCVGG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-131-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="33208" checksum="6762155F9B371E58" modified="2008-01-15" version="1">MSNEATLKISLIMNPASGTSEQGALLLETLAPMSGVTILTTDAAGEGERLARQAVADGAELVVAAGGDGTINEVVKGLIEAERRVPLGIIPLGTGNDLARTLALPTDPLEAWKLILVGERRKLDVIEIRTPRELHYALNVSAGGFSGQLNEAMSSEVKSAWGPLAYLRGALGVLPDLTSYRTTIQYDDQAPEQVDALNIIIANGRTAAAGVQVAPLANPEDGLLDVVIVHYGSIMQLAGAAARLLVNGNYLNSELVELRRAKKVQVISDPEIWFNADGELITNEPIVFEVLPQALEVVVGAEYQAVIEDVTTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5L7</accession>
    <name>A9B5L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1607</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1607"/>
    <dbReference type="EnsemblBacteria" id="ABX04250">
        <property type="protein sequence ID" value="ABX04250"/>
        <property type="gene ID" value="Haur_1607"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1607"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_0"/>
    <dbReference type="OMA" id="VLMVPHA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1631-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="128"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="38901" checksum="9151B35138B20BAE" modified="2008-01-15" version="1">MATTEPTITKKPTSDQALLSRKPRSLWSDARRRLFSSTVGRLGMLICAFLFAVAIITPLVQPLDQTLNRDTANKLQPPSWLMTAEERADAASKSIDKARKDIPWGRFERPFGTDQLGRDIFIRVLHGAPISLTVGTFAVILAVIFGSLLGLISGFFGGIIDTIATWLMDILLAFPSILLAIALTAISNNRESFSYKFSQQITELPILQTIFDPPLFNAMLAVAVVEIPIFGRIARAAVLSVRNQEYIHAAEAVGVSRMRMLMRHILPNSLTPILVQMTLSVASSITSVAALGFLGLGAQPPRPEWGSMLSTAREYVGTGQWWYALFPGIAIMLTVLGFNLLGDGLRDALDPRLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5P9</accession>
    <name>A9B5P9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1639"/>
    <dbReference type="EnsemblBacteria" id="ABX04282">
        <property type="protein sequence ID" value="ABX04282"/>
        <property type="gene ID" value="Haur_1639"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1639"/>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_442645_0_0_0"/>
    <dbReference type="OMA" id="WARLWLF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1663-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="599"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="617" mass="65036" checksum="2D9BACB768949B01" modified="2008-01-15" version="1">MNGQTLLTLAPFGLMMIIALVSWLTGQRLRTRLLGLIASGLTLVALAIVWWLAQGDLPLDVGQRAWLSSYGVGPNPLMRSLLTLHLDGLSLLFAAITLLLASIGFAHLALALGRGLVGYGRLWSGIAIMVFGSLLGILAGDLLLLAFGWGLALLGSTLARQVVGSDDQRTPSALGMSGLSGFAILVAVLSQSVRPEDVLDGSFVMADIGVGQYLRTWLPLAVGVGIALGFPPFGRVLSDDEDTTPALHGLIISAGVPVLAVYTFLRFFGLNLGTWPEAWFAALSYVGALASIVGAAYALRATRFGPLVGWQAVAQWGNVAMALGRYEPNLPLGGEHNTAVVMATLTITVTTLVATMLGAMALGTLERRSGSDLIAKQPALGAPLRAAGLAYALATAAAVGLPALPSFCARRWLMDYTGAGGWSMGVFFVSSGLLLLSFIGSNALFWRVDPQRPVTPVDAGRANDGLLLGLSLPLIGLSLAPEVLVWLLQPALRTLQAVPSPMDDLGSMSWGLRGSLVLGFMLLLFGCFRSQRQAIMPWNGGEQPDRDDGTAHLPAASSRMLSGLAVLGNPRPALRQSHGILQGLSSRIAWVLQFFSGRYYLTGILIAALTIVLLLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Q6</accession>
    <name>A9B5Q6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1646"/>
    <dbReference type="EnsemblBacteria" id="ABX04289">
        <property type="protein sequence ID" value="ABX04289"/>
        <property type="gene ID" value="Haur_1646"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1646"/>
    <dbReference type="HOGENOM" id="CLU_1336001_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1670-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="23050" checksum="E964C6B149B3EDCB" modified="2008-01-15" version="1">MATLTDSYFPFDQPQIASITDLDADGAPEWLFDHGRGFDLLAWVGDRFRINYAFQNQATRVFSATISLAPQLDGTQHVITSFLPDSSGNQPTMSQIEYGLRDGELEQRVPAAPDISPNYGDEYNYSSIATVYQALFERNDPLLALAILAQLEQPLPDRWSQHEAMVLKALALEYNGQFVEAQQLLNVVANDSETTGWSRFVQQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y1</accession>
    <name>A9B5Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3137"/>
    <dbReference type="EnsemblBacteria" id="ABX05774">
        <property type="protein sequence ID" value="ABX05774"/>
        <property type="gene ID" value="Haur_3137"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3137"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3169-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041612">
        <property type="entry name" value="YfiR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17922">
        <property type="entry name" value="TetR_C_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="211" mass="23387" checksum="4F55418EBEE4BD2C" modified="2008-01-15" version="1">MSAQELPLANNQRRGRPREFDRTNALECAMRQFWQHGYETLSMADLTTCLGINPPSLYAAFGSKQAFFLEAIDHYLATRGAYVYAVPSDQSSPRAMLAQLLQRAAEAFSDAAYPAGCFVLSSIATTYDSHEIEQAIVDRCQQRMSKINELVELGVQTGELPATTNADELAQFFICVLQGMSLQARLGASTNQLQAIVANALQLWPQTMRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y4</accession>
    <name>A9B5Y4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-alanine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Larimer F."/>
                <person name="Land M."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX05777">
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        <property type="gene ID" value="Haur_3140"/>
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    <dbReference type="KEGG" id="hau:Haur_3140"/>
    <dbReference type="eggNOG" id="COG0456">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="211" mass="23960" checksum="212A1E486DC64295" modified="2008-01-15" version="1">MYYFLKAMHEDDIPRVQEIERQSFSAPWSANTYRRELSSPATSRYIVARSSPSLPPDEPIMPYVPRRSLLQTLLPSVFTKPQPVSPFPLVGYAGLWLMVDEGHITTIAVAPSQRGQGLGELLLNGLIDQGIDMGATRLTLEVRISNESAQKLYLKYGFEPSGTRVRYYTDNGEDALIMWTDVITEPSYQHRLSELRERLALRLQRQAGMVE</sequence>
</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
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                <person name="Lucas S."/>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Tice H."/>
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                <person name="Richardson P."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
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        <property type="protein sequence ID" value="ABX05800.1"/>
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    <dbReference type="STRING" id="316274.Haur_3163"/>
    <dbReference type="EnsemblBacteria" id="ABX05800">
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    </evidence>
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    </evidence>
    <sequence length="550" mass="60177" checksum="BB4DCB7E254E7ACE" modified="2008-01-15" version="1">MQRFFRSFLIVIMLVLAACGEAAQPTTTTNQTSGPVVGANDLLISITYSPEKTKWLEERITTFNNQNVQSNGKRVIVEGKELSSGTARTQIRAGQLQTTIWTPSASTWLEVLKKESNNPTIAEADPQSLVLTPVVISMWKPMAEAMGYPGKEVGWSDMLALIQDTEGWGKFGQQDWGRFSWGHTDPDISTTALSTVLAELYAANGKTSDLTVEDINQEKSQQFLRDLAQGIKHYGSNTLVFSQNMQKYGMAYISAFPMEEITLIDFNKQAPNVPLVAIYPKEGTFIHDNPFIVMSDATADQKAAASVFYDFLLTPESQNLAMQQGFRPANVDVALASPLTAQFGVDPNQPRNSLATPPADVIVAAKNAWANNRKPANIMLVVDSSGSMRDDDKMDQAKLGVEVFLNRLPSKDNVGMIGFSSSPAVLVPLATRSENMANLQMQTQGLVPDGNTSLYDAIDLARQELENLKQPDRINAIVVLSDGADTASQLSIDQMLGNFGESSIQIFPIAYGADAETSILQQIADFSRTELVQGSTGDIDKIFENLSRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B655</accession>
    <name>A9B655_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase family 39</fullName>
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    <organism evidence="10 11">
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    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
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    <comment type="subcellular location">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ABX06266">
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        <property type="gene ID" value="Haur_3630"/>
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    <dbReference type="OMA" id="THGEARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3669-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="RgtA/B/C-like"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
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            <end position="35"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="199"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="680" mass="76962" checksum="3EABE7E1C0ABCA4B" modified="2008-01-15" version="1">MDERFRWWPTIRRYRLILMLLLVGAAAVRLGLWLLPSHQPANDEVEYLAVARDLLAGQGWRFYDAYPWLRAPLYPLYLAATLWLSNNDPQHALLFNIGLSLIHLWLLWLLGRDWAGDHPHAEKVGLWTAGLASGLLTFATFANLWMSETLWNVLWASSLLLILRWQRTKQLRFALAAGLTIGLTILTRSLPLAFVPVLIGWMWWNWRGWRSVQHGLALGLVACAVVAPWSLRNWLAYGRLITVETGFAYNLWAFSEPALELSEINTILAAIPNPAERADYASAKGRELLAADPSILARKPWTNTVYLWRIKPIEDRFIQANYYSDVALPYLIAALIFDDMWYVLCVVLALWGFARAPRDARWWLALLWVGYIVGSTMFTHGEARYRQFFWPIMLMYAAFSLAKLRVSTPIWQRLGASALGLIIGWVIIDHSPWQLLQQQISRGWWRWQADQALAAGDLAQAEAASLRALNRLPSADGWLALANIKEQFGQADAALEAYIAAANHNRDYPLASYRLGNYLLKRGDLAAAREAWANPYVDRTSLLDWAWRSADRSAETQIDLGAGLDIGLIEGFYPAENLNASTARWSTAHARLRLPAGEAGVVRLRIANPRPGDAPAANLQICVSEQHCIHAELGAEWRVLHLPLAESSNERQIELLAQPWQAPSDQRQLGIVVDWVELAR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D5</accession>
    <name>DTD_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name type="ordered locus">Haur_0186</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B6D5"/>
    <dbReference type="SMR" id="A9B6D5"/>
    <dbReference type="STRING" id="316274.Haur_0186"/>
    <dbReference type="EnsemblBacteria" id="ABX02838">
        <property type="protein sequence ID" value="ABX02838"/>
        <property type="gene ID" value="Haur_0186"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0186"/>
    <dbReference type="eggNOG" id="COG1490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076901_1_0_0"/>
    <dbReference type="OMA" id="GVFQAHM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000127543" description="D-aminoacyl-tRNA deacylase">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <sequence length="153" mass="16540" checksum="295C0514D5FC3207" modified="2008-01-15" version="1">MRAIIQRVANASVTVAEQIVGQIETGLLVLLAVSPSDTSDDLQKLADKILNLRIFPDAHDRFDRSLIDCQGQLLVVSQFTLYADTRKGRRPSFTGAAAPALAEPMVDQFIAYCRGQGITTASGQFGAAMQVQLINDGPVTIILDTAEWQHGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6E0</accession>
    <name>A9B6E0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0191"/>
    <dbReference type="EnsemblBacteria" id="ABX02843">
        <property type="protein sequence ID" value="ABX02843"/>
        <property type="gene ID" value="Haur_0191"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0191"/>
    <dbReference type="eggNOG" id="ENOG5031DS7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1282425_0_0_0"/>
    <dbReference type="OMA" id="WLIMVAF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-194-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="23745" checksum="B8CC8F37905CA09E" modified="2008-01-15" version="1">MTTLGPWIAFGLTLIVLSRAFGENPLFRFSQYLFVGLALGYTLTVVVTTIFIVPSGDMLDNPDSVGTALFIVPVLIGVLLLTRLRTQQFSWLANIPLSLLFGVAAAVAIAGTLLGTLLPQLQASFFSVTSFTDGSNLGAAIGKLVLVIGIVLVLLSFRFSKAATPEAADHTETLKPSLVAKFGRMWLLLSLGAVFAATLITYQSALIDRIQFLLRQIIGVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6E1</accession>
    <name>A9B6E1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0192"/>
    <dbReference type="EnsemblBacteria" id="ABX02844">
        <property type="protein sequence ID" value="ABX02844"/>
        <property type="gene ID" value="Haur_0192"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0192"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441265_0_0_0"/>
    <dbReference type="OMA" id="DSIFMMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-195-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006230">
        <property type="entry name" value="MutL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13941">
        <property type="entry name" value="MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="725" mass="78683" checksum="599CF4BFD264BA81" modified="2008-01-15" version="1">MTTADPAALLVVDIGTLFTHVALLELVAGEYRLLGRAQALSTLEPPIADAWHGILAAIREIEQLTFRAIAHVDGLMTPHRADGSGVDGMVVTTSAAGTLPIVLAAISNDTTGASLRRVARSSYTTVLDMVTLDEYGDPDLAEGESWIDYQLANLVRLPAATVLLAGGIDGGNSAPLERLAHMLGFTVLRLEQINSREFAHVIFAGNTAAYPGIEEALSTIAPITATANVLPAIGVEQLMPARLELIRSYNDRVLPKLPSFNRMRAMSSDMIRCTSDGFGPLVRFIAKHHGRNTLIVDIGAMTSAGYASDGTQLHLTVETNCGTAYGIAGLVDKVGVTNITRWLPFEMSDSALREHMLNRLIRPQIVPIDRESLLIEQALVREALRVVSNDLFDEQPQLASDLIIATGGALTHTMHPAQALLSIVDGLDFGRLQQYRDRSLLISDIYLDRDGLLALCGATAWKYPDASFCLLEQDVLRNGALASYLAINSSLRLGDLVAEVELVPVSGAPIIMQIHHGEIRRLPLALGKRATLRLRPTKQVQIGANLPGEVVETGLAAITGSALGLVIDARPRPLAQRNSDIPSRNQQWQWLNQLGVVDGLNPYAPQYDDQPLPFEMAPALTRIPDPAPAPAQMLPEREEPNAIPDWLREEGENANDLTMPPPSDFGVEEPLPDWLGGMDVPVSSDPVLDLGERRPSQPIAPADFSALRNELEEQNKPKRGFFRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G9</accession>
    <name>A9B6G9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpS</name>
        <name evidence="10" type="ordered locus">Haur_0220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0220"/>
    <dbReference type="EnsemblBacteria" id="ABX02872">
        <property type="protein sequence ID" value="ABX02872"/>
        <property type="gene ID" value="Haur_0220"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0220"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_1_0"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="13"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="195"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="195"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="36196" checksum="7D931FAF34EA7960" modified="2008-01-15" version="1">MGSLPRVFSGIQPSGNLHLGNYLGAIHTWVQEQNQYDNFFCIVDLHAITVPQDPAELRKNVRDLAALYLAAGISLEHATIFVQSHVPAHVELGWILNCQTPLGWLNRMTQFKDKSQKQETVAAGLMNYPTLMAADILLYDTQVVPVGDDQRQHIELTRDIAERFNHLYGETFVIPEALIRPVAARVMGLDDPTQKMSKSNKAANHSIPLLGDLKATRKAMMRAVTDSGSEIKFDETRPGVNNLLGIYQALTGKDKATIEAEFEGQGYGKLKGAVADVVIATLEPLQQRYNQLTADPAELDGILKRGAERAAEVANATLLRAYQQLGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6P4</accession>
    <name>A9B6P4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1710"/>
    <dbReference type="EnsemblBacteria" id="ABX04353">
        <property type="protein sequence ID" value="ABX04353"/>
        <property type="gene ID" value="Haur_1710"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1710"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1737-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="19"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17431" checksum="11A689D45646A496" modified="2008-01-15" version="1">MVGAAFRPKPTIVAPAQAKVMVIEDNADSMDLALLLLRERVNVAYCNARASGEAFFNWLSSPQVQQNPSLGMLDLILLDIRIPRENGYMVLQKLHVLPDFKRTKIVAMSAYSSREDVERMRAAGFDGFVAKPVSVKTFPDYIVRILRGEAIWDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X0</accession>
    <name>A9B6X0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3201"/>
    <dbReference type="EnsemblBacteria" id="ABX05838">
        <property type="protein sequence ID" value="ABX05838"/>
        <property type="gene ID" value="Haur_3201"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3201"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049717_1_0_0"/>
    <dbReference type="OMA" id="IGHQWAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="33828" checksum="E5F1ACA5AB39BB72" modified="2008-01-15" version="1">MMSGELHVIFGTGPIGKATARCLVSAGKQVRMINRSGKASHLPESVEVLAGDIYDQHFVAQQAQAATSVYQCAQPAYYEWTSKFPAMQAAVIEGVAQSKAKLVVMENLYGYGRSNGQPMTETTPFAAHTRKGKLRAQMSEQLFAAHNAGKIRATSVRASNFYGPEYQLMGDQVVKPALQGKKVNLLGKADVLHSFSYVNDIGASLAILGTDERGLGRPWHAPSPAALTQQEFVAILAKVLGKPVGYRTVNTAMVWLLGRFIKELAETVEMMYEWQAPFIMDSSAFSKTFELEATPIEQGIKAMADWFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X8</accession>
    <name>A9B6X8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05846">
        <property type="protein sequence ID" value="ABX05846"/>
        <property type="gene ID" value="Haur_3209"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3209"/>
    <dbReference type="HOGENOM" id="CLU_162021_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3244-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14437" checksum="9E3339AA4A4F0765" modified="2008-01-15" version="1">MLRTIRSLRWFGWYAVSTGLLAALAPNLLLSVFGMPTTTEVWPRVAGMLVGFIGVLHMNVSPIDLRRYAMTTVILRLSVPLIFGWWVITGAGPWQLLFFAGADVVGALATLWGLRVDQQMGNPRQTSAIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B715</accession>
    <name>A9B715_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_3246</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3246"/>
    <dbReference type="EnsemblBacteria" id="ABX05883">
        <property type="protein sequence ID" value="ABX05883"/>
        <property type="gene ID" value="Haur_3246"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3246"/>
    <dbReference type="eggNOG" id="COG0015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025566_2_0_0"/>
    <dbReference type="OMA" id="TQVNPCD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3281-MON"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="17"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="333"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX05883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="458" mass="51379" checksum="B8EDD6B12CB26773" modified="2008-01-15" version="1">MSEINQQALLAIGPLDGRYRKDVEALSGHFSEAALWRYRVRVEVEYLLFLARAPRIGLIEGIDGQLAGALRNLYRQFSVDDAVAIATWDRKVNHDVKAVEYWLREKLDLLGLGQYKEAVHFALTSEDVNNLAYALMVQESRDVVLLPALGNILGLLRDMQIEHAEAPLLAKTHGQPATPTTMGKEIAVFAARVNRGIEQLLHIRLTGKLNGATGTYAAHYAAFPDVDWITFSSAFVKFLGLEPTLLSTQIEPHDSIVEVGDALRRVNTILVDLSQDMWRYISDSVFGQASVAGEVGSSTMPHKVNPIDFENTEGNLLLANSLLEFFGRKLPISRLQRDLSDSTVLRNLGVAFGHSLFAYQRLLKGLRKLAFNTEKAYAELAGHPEVLTEAIQTILRRERYPEPYEAMKKLARGRQITLEDLHSFIDELEVRPEVREELRALRPETYIGLAAKLARKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B724</accession>
    <name>A9B724_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3255"/>
    <dbReference type="EnsemblBacteria" id="ABX05892">
        <property type="protein sequence ID" value="ABX05892"/>
        <property type="gene ID" value="Haur_3255"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3255"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_756003_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3290-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="316"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="38888" checksum="E1381EDA037A189A" modified="2008-01-15" version="1">MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIVALQFLPNQQLLVGVGYDGVYRWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTWNSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQIIAAYNKGSMLQAWNVATGAATTTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLAWSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSGLIELYDLTSKQVSNSLKGHAERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVLPATPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B731</accession>
    <name>A9B731_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3262"/>
    <dbReference type="EnsemblBacteria" id="ABX05899">
        <property type="protein sequence ID" value="ABX05899"/>
        <property type="gene ID" value="Haur_3262"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3262"/>
    <dbReference type="eggNOG" id="COG3881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1203504_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3297-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="24220" checksum="CAB81CAA8E7758EB" modified="2008-01-15" version="1">MYKAGELVKKSIIRVDTGNIIGSVADLLVDHDAGRIVGLLTSTGGLFREATIVEWAQVLVWVGDVILVKAGCEVLRANAIPHVHALLEKKIHLTGTPAIGRSGNKLGTIGELLLDETGLIVGYVITRGVLKGERQYVLSGGIAGIGSDAVVVYDEALRDTLEGLEPSIPDPKLTMVMPLTGTRLSVEAPATPANPAESKPSPTDVQRLSSNEIDAILRGDQPIPGATSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B735</accession>
    <name>A9B735_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3266</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3266"/>
    <dbReference type="EnsemblBacteria" id="ABX05903">
        <property type="protein sequence ID" value="ABX05903"/>
        <property type="gene ID" value="Haur_3266"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3266"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089201_0_0_0"/>
    <dbReference type="OMA" id="WSRNFLN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3301-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="27"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="31427" checksum="10F7D95222E3F13B" modified="2008-01-15" version="1">MAFGRSFWRETRASYAFVERNINLIKRYWGWEVVWLIYSIVNALSITFIGKAVGAITGQEFDQATINATILYLIVGTLVWHYLAVVFDCIAESVQWERWEGTIEYTFMAPISRLTHMLGTTIFAIFWGLFHTGIILAFVAVFFQISLENANFLGATVILLTGSISFIGLGIVAAVLPLLFPERGAQMTNIVKATILLVSGVYYPISVLPTWMQPLASVSPATYVLEGMRRALQNNAGPLDLWASYLLPLLGSGLLLVPFGLWIFLRGEEYAKRTGRLKRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B796</accession>
    <name>A9B796_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3743</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3743"/>
    <dbReference type="EnsemblBacteria" id="ABX06379">
        <property type="protein sequence ID" value="ABX06379"/>
        <property type="gene ID" value="Haur_3743"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3743"/>
    <dbReference type="eggNOG" id="COG1482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020529_0_1_0"/>
    <dbReference type="OMA" id="DYDRCND"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3785-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014628">
        <property type="entry name" value="Man6P_isomerase_Firm_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036894">
        <property type="entry name" value="PMI_Firm_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="35822" checksum="C105BA2D28227BED" modified="2008-01-15" version="1">MEAKTLPPIQLEARYDSRVWGGNRLAQWLNLPNAPSPLGEIWLVYAENIIAAGPLQGQTLAAAAERYGALLLGSVPFERSGSQFPLLAKFIDAADHLSVQVHPNDVYAHTVEATTGFNGKTEAWYLLQTEANAQLIHGFNHQTSREQCSELIANDRLPELLRYVPAHAGTTIFVPAGTIHAINAGVMLFEIQQTSDLTYRIYDYGRPREMHIERALDVLDYAASAPAETPPTRLDSRRTLLVKCRYFAMERWQLHGRVDSATLPTSFEIITVIDGSATLRSFHGVWELTLGTTLVLPASLGAYTYEVANSVTLLRCYVPTEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D5</accession>
    <name>A9B7D5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3782"/>
    <dbReference type="EnsemblBacteria" id="ABX06418">
        <property type="protein sequence ID" value="ABX06418"/>
        <property type="gene ID" value="Haur_3782"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3782"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3824-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="70"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="384" mass="41711" checksum="9D77D92070EBE4C5" modified="2008-01-15" version="1">MFTTMSTAPRDWLASRAEFPILSRKTYLNTCSLGALSSRVRAAVNQHLDLWEEYGASAWYKIWLGECAALRTTTERLFNAPAGSVALAPSVGVALSVIASALDYRQRPKVISSVLDFPTIPYQWLAHPEVEVVLLPSPDGVHVPLEAYEAAIDERTALVATSHVFFASGTIQPIAEIAKLAHAKGALCLIDGYQAAGQVPVDVVASDLDFYMTGGLKWLLGGTGIVECYVRPSLIQQLKPTVAGWFGHANQFAFDPNNFEFAPDARRFEVGTPALSAVYAGHAGMQIILDHGVAAIQQRTSELVAYLVAKLRDAGYQLTISGDPQQHAGIVMIQSAEHAKLVAALAEQGIIVDHRPGHVRVSPFFYTLETELDLFVERLQALSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7J5</accession>
    <name>A9B7J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0316"/>
    <dbReference type="EnsemblBacteria" id="ABX02968">
        <property type="protein sequence ID" value="ABX02968"/>
        <property type="gene ID" value="Haur_0316"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0316"/>
    <dbReference type="eggNOG" id="COG1235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044538_2_1_0"/>
    <dbReference type="OMA" id="CGPDFRQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-319-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="34"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="255" mass="28214" checksum="3884EAA1FCAD4567" modified="2008-01-15" version="1">MQLTILGCGGSMGVPMLACDCVVCTSTEPRNQRTRTAALIQSPTTTILIDPGPDLRLQGLRHNLQQLDAVLVTHPHQDHIGGIDDLRPFTLHTQRMLPLYANQFTLDRIRYQYDYAFASGESASTRPSLGLNLLDGSALQIGDVPIIPLPIDHGDWQILGFRIGDLTYMTDVSHIPEPTFEMLHGVKSLIIGALRHEPHPLHFTVEQALAAVARIQPEQAFFVHMSHSLDYNTEHATLPKHVQLAYDGLVLPIGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R3</accession>
    <name>Y1798_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0060 membrane protein Haur_1798</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">Haur_1798</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0060 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B7R3"/>
    <dbReference type="EnsemblBacteria" id="ABX04441">
        <property type="protein sequence ID" value="ABX04441"/>
        <property type="gene ID" value="Haur_1798"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1798"/>
    <dbReference type="eggNOG" id="COG1742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117653_0_1_0"/>
    <dbReference type="OMA" id="WLWAVEG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1826-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00010">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003844">
        <property type="entry name" value="UPF0060"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36116">
        <property type="entry name" value="PTHR36116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02694">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000089244" description="UPF0060 membrane protein Haur_1798">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00010"/>
        </source>
    </evidence>
    <sequence length="110" mass="12118" checksum="9FBC39AEB5CCC1B7" modified="2008-01-15" version="1">MQVFRAVVLFILAGLAEIAGGYLVWQWLRADRSIWFGVLGAILLVGYGFLPTLQPQVWSFGRVYAAYGGVFIVLSLAWGWLIDHNPPDQPSLVGACLALVGAAIILYWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z5</accession>
    <name>A9B7Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S ferredoxin, iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3291"/>
    <dbReference type="EnsemblBacteria" id="ABX05928">
        <property type="protein sequence ID" value="ABX05928"/>
        <property type="gene ID" value="Haur_3291"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3291"/>
    <dbReference type="eggNOG" id="COG0348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017386_1_0_0"/>
    <dbReference type="OMA" id="VQNITML"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3328-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="470" mass="53290" checksum="765905CAE4721D29" modified="2008-01-15" version="1">MQQLPAIDLLKLPGLRWLGRWRYARFALQMPLFAMAMLMVWDGMTGAQLAPKNSATVLVWVHYRGFLMLALLVVGNLFCMACPFMLPRNLARRWLKPRFKWPSWLRNKWLTTGLLVAFFFVYERFDLWASPWWTAWLIVAYFVAALLIDSSFQGAPFCKYVCPLGQFNMLSSTLSPIEVAVRQPQRCQTCQTKDCIVGRDEQPGCELWLFQPKKVGNLDCTMCLDCIHACPHDNIGLLARVPGQELISLEPRSGIGKIEQRSDFSLLMLVFTWGALLNAFGMISPVYSFYNWLTSQFAISSETFLLSVVFILALVIEPVALLGGAAWLFRRISGHSERLIAIINRFMKGFLPIGIAMWTAHYAFHFIIGFWTILPVLRSLLAEAGINFSWMPVTGLSPLVPQVMIYPFQIGMILLGSVLSAVITWQTTTTLTKQRQQLAWLPWALVIVAMAGSAMWLLSQPMDMRGILEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B814</accession>
    <name>A9B814_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3311"/>
    <dbReference type="EnsemblBacteria" id="ABX05947">
        <property type="protein sequence ID" value="ABX05947"/>
        <property type="gene ID" value="Haur_3311"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3311"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1693097_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3348-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="42"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="16987" checksum="2978A503A6BEADE0" modified="2008-01-15" version="1">MRLAGCRSQSEVLPTVVWAWPMVAWALAKDNYVRKLMQSPISFTQLTLAATNIEQMAAFYNSVLFTNFRKIKHGEHTLYEGFLVNIPLLLCPNAIAGVVAEQSRLQFHVCVPDLARALEKVVQHGGTIVTPPSAGGIKAAIVTDPDGNSLELIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B885</accession>
    <name>A9B885_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3802"/>
    <dbReference type="EnsemblBacteria" id="ABX06438">
        <property type="protein sequence ID" value="ABX06438"/>
        <property type="gene ID" value="Haur_3802"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3802"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_2_1_0"/>
    <dbReference type="OMA" id="FPYKRLF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3844-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="315" mass="33217" checksum="1DEC70E09D6FB4D2" modified="2008-01-15" version="1">MVAPASWPKLITGILLPGLTLAAIYFMISAGLSLIFGLMDVLNFAHGSLFMLGGYCAWTCNVWLDPNYAGHWPITIASGNLRFIIGLIVGTLVGAAVGSLIEISLIRPLYKRPIYQVLLTLGLVFVFDALVRTIPAWGSLSRAPIKPPMLTESLSLLGRRFPSYSLFLICLSVSLAVLIALVLRRSRIGLTIRAGVQDSAMVEAMGINVRRVFTGVFGFGSGLAALGGAVAASFIGVYPEMGLEYQLFAFIVVVIGGLGSYSGAAAGALLIGLARTFSDHLVLETGLPTAIASASTVLVMAVVLLLKPGGIFNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B898</accession>
    <name>A9B898_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3815</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3815"/>
    <dbReference type="EnsemblBacteria" id="ABX06451">
        <property type="protein sequence ID" value="ABX06451"/>
        <property type="gene ID" value="Haur_3815"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3815"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_1_0"/>
    <dbReference type="OMA" id="VDNFPGY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3857-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="5"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="316" mass="34395" checksum="80DB9201AD932BAD" modified="2008-01-15" version="1">MEKQKVTVIGSGPAGLTAALYAARANLTPLVIRGIQPGGLIATTSEVENYPGFPDAINGFDLADKMEKQAARFGTHFLDGIVEKVELGERPFKLHIDNGTIVETETLIIATGASPRKLGVPGELELANRGVSYCAVCDGFFFRDKTLVVVGGGNSALDESLFLTRYAKEVHIIHRRDQLRADPVLIERAQNNPKIKFIWDTVVTKVEGTVKVEGVALHNVKTGEESTFAADGVFPYIGHIPNTWLFKDQIELDENGYIVSPGRARTNVPGVFVAGDVEDHVYRQAITAAGSGCMAAMEASWFLDQIEHEQTSLAQW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8B9</accession>
    <name>SYFA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="1">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pheS</name>
        <name type="ordered locus">Haur_3836</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B8B9"/>
    <dbReference type="SMR" id="A9B8B9"/>
    <dbReference type="STRING" id="316274.Haur_3836"/>
    <dbReference type="EnsemblBacteria" id="ABX06472">
        <property type="protein sequence ID" value="ABX06472"/>
        <property type="gene ID" value="Haur_3836"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3836"/>
    <dbReference type="eggNOG" id="COG0016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025086_0_1_0"/>
    <dbReference type="OMA" id="DWHNFTA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000114882" description="Phenylalanine--tRNA ligase alpha subunit">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>shared with beta subunit</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <sequence length="346" mass="39289" checksum="FD98D422653B2D47" modified="2008-01-15" version="1">MFEQLDQIEKEAAAALASVQSLDDLAAWRTQWTGKKGALAQASQSIGKLDPKDRPAFGQRFGAIKQALSEQETTLEARLQSAALHQELEEDAVDISLPGRAANIGRLHPSTQSLRRIQHIFAEMGFQVWESREVESDEYNFELLNMPAHHPARDMWDTFYVQSDDPHQKVVLRTHTSPGQIHVMRTLNPEPIRVILPGKCYRYEPVSARSEMMFHQVEGLVIGKNITMADLKGTLANFARRMFKDDVKVRYRPSYFPFTEPSVEVDIECFICGGEGCRICKKSGWLEILGAGMVHPTVLRNGGYDPAEWSGFAFGMGPERQTMLRYDIDDIRWFFSNDGRFLEQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K2</accession>
    <name>A9B8K2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="CAZy" id="PL9">
        <property type="family name" value="Polysaccharide Lyase Family 9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07666">
        <property type="protein sequence ID" value="ABX07666"/>
        <property type="gene ID" value="Haur_5036"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5036"/>
    <dbReference type="HOGENOM" id="CLU_489819_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5099-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="556" mass="61043" checksum="C25BF028729458F2" modified="2008-01-15" version="1">MAATWKYGRILGHGVIGRLFGMILLRISEREASIILHRIQAALYSSRPFYSIHHRYNAATDWLFAYFFPDNLMGDLLIIFLNRRRPMAFITSSDLCLVLIHRSLRGRLLVWQAAIMVAMALLPGNSLAASPNQSYEVGPGRTYARLSDLVSADVLGPGDTVLVYPNGTASYNDTVIFDTHGTADRRITIRGVRVNGQRPILSSNNNYGIVFKGDHYIFEGFEVTGAVGNQYVIIHRADHILIRDTLIRDCPGTGLLGHDEDAGSLTLDHVEVTNCGNGLYQHPIYMTTGLPGAVFRMQYCYLHNQKGGNGVKSRANRNEIYYNWIEGSYYHELEMIGPDDGTGGSPDSPRHSDVVGNVFIKKQDFATLVRIGGDGTGQSWGRYRFVNNTLVGRSDGAVAIRAFDGLQSIELHNNVFTNANGTGMRIIRDTEATWHNGLRVVAGINNWIQAGSVSAPELIGTIQGTDPQFVNLATGDVRPSTNSPLINVGTSNPASPTGYPFPSPLMLPKQHPPLRTIAPVTVVDARPVVGAIDVGAYEIGIPPLYTNRVYIPIIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K8</accession>
    <name>A9B8K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07672">
        <property type="protein sequence ID" value="ABX07672"/>
        <property type="gene ID" value="Haur_5042"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5042"/>
    <dbReference type="HOGENOM" id="CLU_038153_1_0_0"/>
    <dbReference type="OMA" id="LDTQYFH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5105-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="374" mass="41606" checksum="F0FBCACB6A939B03" modified="2008-01-15" version="1">MITLNAIVQRSGAAYRAQCGTRLSDHQRRVMHAIEACRTEALGGQVFTCPACQTLRYSYHSCRNRHCPTCQQDAGAAWLTDQQALLLAVPYFLVTFTIPAELRPVARANQAQVYAAMFRASAAALQQVAADPRHLGGQLGMLGVLQTWTRDLRYHPHIHYLIPGVGRTATGQLVFPPAENFLLPMRPLAVLFRAKLRAALRQIPHGTVIPAAVWEHDWVIDCRPVGTGETALKYLAPYIFRVALSNNRLLSADDDQVTFRYRHSDSGENRTSTLPVNTFLDRFMAHILPKGFVKVRYYGFFRPAVRADLRRIQAQLWLLRRHGQFDPGIPQPAALARGAQITPCPVCGIQMQGRHLAPRSARAPPQSVNAPGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L8</accession>
    <name>A9B8L8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07682">
        <property type="protein sequence ID" value="ABX07682"/>
        <property type="gene ID" value="Haur_5054"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5054"/>
    <dbReference type="HOGENOM" id="CLU_2633250_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5116-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8117" checksum="D363C71F81A8B33B" modified="2008-01-15" version="1">MITVTLHGRVAHGTLEFDQPIAVPTSVADGTHTVLVAIAEPAVTESALATWPADFFDATFGSCPDLERPDQGVLPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8M5</accession>
    <name>A9B8M5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07689">
        <property type="protein sequence ID" value="ABX07689"/>
        <property type="gene ID" value="Haur_5061"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5061"/>
    <dbReference type="HOGENOM" id="CLU_1084923_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5123-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="256" mass="27650" checksum="35BC6B02FB6F4319" modified="2008-01-15" version="1">MSWIVTIGLTAMQEQRVREIGETVIATSNVFAAEYQLLALLDGDTPNPGLVVCRAVDAHGVATWLLGAALVMQMQAGTLQRCAMAVLDEDLATIVHTQLVPGLQVVAPILPSALTPLVRDLPLLGEPTGSTEHAAATYRALRRSLPLVLDARTAAQRSHWTLDDVMMVLHVVSGRLTQVSPAIQARLVEVGGIVGFRRWLQAQAQDGLWLNEQQQILLGLAQGKNYSELGYALGRSRDWIGRMVRSQVAPALAAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8V6</accession>
    <name>A9B8V6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrin alpha beta-propellor repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07770">
        <property type="protein sequence ID" value="ABX07770"/>
        <property type="gene ID" value="Haur_5142"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5142"/>
    <dbReference type="HOGENOM" id="CLU_025051_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5204-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="529" mass="56464" checksum="D8505B406AD1ECD0" modified="2008-01-15" version="1">MHVHFIKKRNPMVLVVVFIGIWLLTMMPPTRHTAAIPHGLTTHDWQILTSFFPPTQQAFFKASNTGPQDFFGSRVAVDDDTVVITAPQEDSSTTGVNSTPNEEASESGAAYVFVRTNGLWTQQAYLKPSNTSPGDAFGESVAIDQDTIVIGAFKEDSSTTGVNSMPNEEALNAGAAYVFVRTNGLWTQQAYLKASNTDADDAFGTAVSVSQDSIVVSAINEDSSTTGVNSTPNEEALNAGAAYVFVRTNELWTQQAYFKASNTGADDMFGRSVALYATTLVVGAYLEDSNTRGVNNPPNEAAPDAGAAYVFERVNGHWVQQAYLKASNPGETDRFGISVALESSTIVVGAYLEDSSTAGGQSDPNEQAPDAGAAYVFVRIMDTWYPQAYLKASNIDAGDRFGASVAVHGDLLLIGAYLEASSSSGIDSIPNNDAPGAGAAYLFLRTNHRWTQQSYLKASNTGLNDTFGIRGALYQGTIVIGAYQEDSSTVGVNPPSNEEASDSGAAYVYTTTMLVPNPHRAYLPWAGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y2</accession>
    <name>A9B8Y2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07796">
        <property type="protein sequence ID" value="ABX07796"/>
        <property type="gene ID" value="Haur_5168"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5168"/>
    <dbReference type="HOGENOM" id="CLU_962322_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5230-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="31558" checksum="997CDDB4E81224B0" modified="2008-01-15" version="1">MTNPPDPSPSTTFFKNAITTLSGITVYLVALLWLMGRSYSRGYHETLAIPPSSLVFSIWDYGELGWVLLWRVVVLLLCILLFQAGVPSTKKMPWKAAALMAVCLFVMAKGLGFSWLWAGIYGVIIPILIGGRAEWETLRGELPDAIRIPLMESFFAMALGIFLLEGGRVMALEHGQRAAVNTFKDDPIMTTDLVLTQPLLGLPMGSSALTTTDVYTYTKLLVVTTNTDQLFVTSALTTACLPTMVHVIQADTIQQQTYTTHPKGSMPCGTTIHTPPLSSTTTIPFTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B969</accession>
    <name>A9B969_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5256"/>
    <dbReference type="EnsemblBacteria" id="ABX07883">
        <property type="protein sequence ID" value="ABX07883"/>
        <property type="gene ID" value="Haur_5256"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5256"/>
    <dbReference type="HOGENOM" id="CLU_717230_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5318-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="44830" checksum="49440FB17F9B1A5C" modified="2008-01-15" version="1">MIILSLPLTVAIGRYGILPLLVIGASFHARRIYQDNKRLGILVIIKMLLGIGLLLISALTALVKPTIWWVHWIGSTSFHFSILFSYFAIDQYINNKFDLEIIRNRLFIGLVILSLFRIYLEFERRNNLYSFMENEVPSPTFNYYISTLLHYLPALYLNAIIANLYWVNIRKAKLTPSYFIRRLFCLCGFVMATFAFISLTATIPLAIFFTDQYRPYLNNVYHLGKPIILLFLMAGMTFPNRLFKAIAWPIEKFLIWRDREQYKLLIYLMDSYNTIIPSQQYRSRIKRSADYVMPVKRINASIGDGRLLVLSHLALHDPNPQKEAEYIFHLLRDQVVIQTPGSFQPPQSPHDITKYNIKVAKRLKALINANQGILEFHQVSDKVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU90</accession>
    <name>A9AU90_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0358"/>
    <dbReference type="EnsemblBacteria" id="ABX03009">
        <property type="protein sequence ID" value="ABX03009"/>
        <property type="gene ID" value="Haur_0358"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0358"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_2_0_0"/>
    <dbReference type="OMA" id="PRCHDEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-361-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="84"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="533" mass="57824" checksum="051ED61530D0BE18" modified="2008-01-15" version="1">MRRWNGWGDESKEYPVKAGILGLLKQLIGAGTAPSDVRLAEIVAQVPASRLPHHELISTDPELRIRHARGQSFADLVATRSGELGQIPDGVAFPQSSQAVRELIDWASDNNVSLIPYGGGTSVAGHINPVAGERPILTVSLAKLNRLMEINPTARLARFGAGIKGPDLEAQLRALGFTLGHFPQSFELSTLGGWIATRSSGQQSLGFGRIEQLWAGGRVETPRGSLELAPFPASAAGPDLREMLLGSEGRYGIITEVTVRIRPIPELDVVHAIFFANWEQAQTAARTIAQANLPLGMLRLSTPTETMTNLALAGHERVIGLLEGFLKLRGVGSEKCLLLVGFIGSQAQVKLSRQAVLSLMRRHGGVHIGQSFGKAWQAGRFRAPYLRNRLWELGYGVDTVETATTWENVTPLLNRLEHSLRHGLAAEHEQVHVFTHLSHFYPTGSSIYTTYAFRLGNDAQATLARWHALKTAASQAIVAAGGTISHQHGVGLDHRPYLEAEKGRLGIGALQQLGQHFDPQGLLNPAKLYEDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUJ0</accession>
    <name>A9AUJ0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1874</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1874"/>
    <dbReference type="EnsemblBacteria" id="ABX04517">
        <property type="protein sequence ID" value="ABX04517"/>
        <property type="gene ID" value="Haur_1874"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1874"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_2_0"/>
    <dbReference type="OMA" id="EYPTARF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1903-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1553" mass="173797" checksum="184B8664BD0440BF" modified="2008-01-15" version="1">MSDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQLDPQSALYNVPVVIRFGPNFDVALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFRLPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRVVLLRLTHEHHLIINLHHIVSDDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQLSGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKILLQHYTGQTDLLIGTPITSRTRPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMALDAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQEARQKMPENVLGYAEVDTGTSKFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVTSAERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLATYLQQLGVKPECVVGLCVERTPAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPLVVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQLQPSNLAYMIYTSGTTGTPKAVLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEILDIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNAMRLAFPQAAIHVLYGPTEATIICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPIGMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTGDLARYQVDGNLEFLGRIDQQVKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAFLQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLSTIWAEVLGREQVGIHDNFFELGGDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVSSTTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMPVLLEAPAELTQADLHSIVAQLLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKLDLSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLKTSSFKTWALALQEYAQSPEVAQQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEVAETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLVVDLESHGRAESIAENLNLSRTIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAELRFNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLHEPATITQLAERFMAALRDLLQGDSATSAAYVPSDFPMANLDQQTLNSLMKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP5</accession>
    <name>A9AUP5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1929"/>
    <dbReference type="EnsemblBacteria" id="ABX04572">
        <property type="protein sequence ID" value="ABX04572"/>
        <property type="gene ID" value="Haur_1929"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1929"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037493_1_0_0"/>
    <dbReference type="OMA" id="VAVTYCP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1958-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021516">
        <property type="entry name" value="DUF3179"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11376">
        <property type="entry name" value="DUF3179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="372" mass="41891" checksum="046A971F56484A5A" modified="2008-01-15" version="1">MSTRPQAPQPTAHEPTTRTFGHDWQTDFSRQLVDYREFTLGNPRRDGIPPINQPQFESIDQANDWLSPDDPVLVVSNQQHTTIYPLQILMWHEIVNDWLGELPIAVTFCPLCNIGVVFERQVANQRLTFGVSGLLRKSDLVMWDRQTESLWQQATGLGLVGHFAGSQLQMLPSLLVAWQIACEQAPTSRVLSRQTGFRRSYGQNPYIAYDQQTTPWLLQQRPNPQLPALERVVGLVIGNAALAYPFSILARRLVINDHYLDTSIAIFYQAGMASAVDAATIAQSHATGMGTAWQRQLDGMLLSFESRDHAIYDHQTNSRWDISGRALAGPLQGRQLTPIIHGNHFWFAFAALIGERTQTLRLYSDVDAMDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV2</accession>
    <name>A9AUV2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3906"/>
    <dbReference type="EnsemblBacteria" id="ABX06540">
        <property type="protein sequence ID" value="ABX06540"/>
        <property type="gene ID" value="Haur_3906"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3906"/>
    <dbReference type="eggNOG" id="ENOG502ZUZ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1394677_0_0_0"/>
    <dbReference type="OMA" id="EVPYRIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3948-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="20636" checksum="2159639E9522C5C3" modified="2008-01-15" version="1">MVGCTQPGGLNLQSLTQTPANATVSGSNPSTQPSSPSQTNVTGQPTQIQVPTVVVDGPTSQVNSTSVPVEPSSVVPTVVLTPPPSGNAAWEAQKVDVQQFAEPIAYDAPGAVMLWWYDPISGQYVGLGWVRSPLIASGEFRLRWSALAALAIPYTINVDYGLSLEPSVIQRIRRAGYSGDVIETFVYLAPDITPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV4</accession>
    <name>A9AUV4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3908"/>
    <dbReference type="EnsemblBacteria" id="ABX06542">
        <property type="protein sequence ID" value="ABX06542"/>
        <property type="gene ID" value="Haur_3908"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3908"/>
    <dbReference type="eggNOG" id="ENOG502ZFQ0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2583314_0_0_0"/>
    <dbReference type="OMA" id="LGRRCYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3950-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="9470" checksum="2D939FE76467F496" modified="2008-01-15" version="1">MRGRLHSTDERLIDDDLTELADELSIRLYATMGHRVYLLSRPDIIQLTKSYIDDLHPEDQDAICWLIWDLFQEGMQMEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV5</accession>
    <name>A9AUV5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3909"/>
    <dbReference type="EnsemblBacteria" id="ABX06543">
        <property type="protein sequence ID" value="ABX06543"/>
        <property type="gene ID" value="Haur_3909"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3909"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025669_0_0_0"/>
    <dbReference type="OMA" id="IWELFPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3951-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="683" mass="78035" checksum="B47BDAAAB8D3EAA8" modified="2008-01-15" version="1">MHVYARIDIEWSAAPALIHASLAARQGWLLGAVIADRWLWADQTWQITPNHSSQRLHWQAQSITQPSLKADLLLELLDSVSSTHVRATLHVEWPKTTFKLWRYWQRRRWLHNELTNVLQHWRDAWTTQSTPSDQLAQSHPRTWQAFHTMNALDQLQRIQALDRRWQQFEHGQLPNLPYSQTDQLPKADLAVDLVYAGGGLGLIHATLMARKGLNVLVFDRHQVGCAHREWNISQAELERLVATGFISWEILERQIIMARYHDGIVRFHAAGSAVAPAELHLPEVLDIALDAGALLDYARQQFLAAGGIIWDNTSFEHVYHDPKQQQTVVAVHKADQTQLIAARLLIDAMGATSPLTLATQPFAGICPTVGTVLSGAEHDQNLGDILISIADTQADRQLIWEGFPGREHELTVYVFYYDQVGAKAKYRHSLLDLFEDYFELLPSYKQLQANAQHLRPVFGYIPARHALNKPKPLAGVLALGDASAQQSPLTFCGFGSFVRNLSRTTDLLEQALEQALLAPQQLSLISAYQSNVSMNWVFSRFMTPWGRPQDVNELQNVFAHVLNRLGYDLARRFFQDQMTWHDYNRVVLGTLAFYPRIMQVAWQVLGWRDWLRWIGDWLRFSRAAFIAQFGQQLPSWLVGRLPKPWLFQYNAAYAEWRAMGWLKSSPEHQSQALGSQPSIKQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV95</accession>
    <name>A9AV95_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0525"/>
    <dbReference type="EnsemblBacteria" id="ABX03173">
        <property type="protein sequence ID" value="ABX03173"/>
        <property type="gene ID" value="Haur_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0525"/>
    <dbReference type="HOGENOM" id="CLU_823288_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-534-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="337" mass="38497" checksum="D5ADB21243B0F521" modified="2008-01-15" version="1">MNSGMPSRAGVSNRVCCTLFVNLWRNVQPILLMMESRRCMAPQSDRIQVRWRNGWTAIPHTILRDSRLSRSARLLWGILASYAGNEEAAWPQQKDLAQACAEDDKVPHIRTIQRWLKELETYGWLASIQTRHGNIYELFESQQRDTSVEETTPVSCQTRHQDRVRGDTSVVSEATPVSHGLINKNQLIRNNNNTPAAQPKKPTDTETYRLLRDRQVWTAKKHAHEPLEIIQAYLDHVGPNYPAAQIALDLKAGVHHRLTPEPEPSPPHTEPANDDRRPAWIGLDQWQGLTSNQRDALQYAQLVNGRIQAQYDDWTEMIYKRWGPLANRLVEAAGGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH6</accession>
    <name>A9AVH6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Xenobiotic compound monooxygenase, DszA family, A subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2024"/>
    <dbReference type="EnsemblBacteria" id="ABX04667">
        <property type="protein sequence ID" value="ABX04667"/>
        <property type="gene ID" value="Haur_2024"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2024"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_1_2_0"/>
    <dbReference type="OMA" id="QVEGYHL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2053-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01095">
        <property type="entry name" value="Nitrilotriacetate_monoxgenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="152"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="224"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000337-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="460" mass="51340" checksum="DF57DA99268412C3" modified="2008-01-15" version="1">MKPQRQMKLGAFLPAPGHHVAAWRHPNTPANAGLEIQHYTQVAQTAERGKFDMLFLSDGVGIRTHYKDEDELSRWGRIVQFEPLTLLSALAMVTQKIGLTATASTTYNEPFHIARKFASLDFLSNGRAGWNVVTSVTDVEAQNFNLQHQPDHATRYRRAREFMDVVTGLWDSWEDDAFIFDKATGRYFEPQKLHMLHHRGEFFQVRGPLNLARSPQGYPVIVQAGSSEDGQDFAAQWAEVIFTAHQTLEQAQTFYRGIKGQMIKHGRSPEQAKVMPGVFAVVGQTRAEAEAKYAILQELVDPVVGLGLLTGLLGDVDISGYPLDGPLPELPETQGSTSRQKLVYEQAQRQGLTIRQLYLSVAGGRGHRFILGTPSEIANQLEDWFVNEAADGFNIMPPSLPDGLNDFVDLVIPELQRRGLFRTDYEGTTLRDHLGLDRPLNRPNKSTAERATLAIARGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH7</accession>
    <name>A9AVH7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2025"/>
    <dbReference type="EnsemblBacteria" id="ABX04668">
        <property type="protein sequence ID" value="ABX04668"/>
        <property type="gene ID" value="Haur_2025"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2025"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_0"/>
    <dbReference type="OMA" id="HYTDRHR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2054-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="25"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="115"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="320" mass="34732" checksum="C9835E381B21F526" modified="2008-01-15" version="1">MTKLRCAILDDYQHAALAMADWSVVAEQVEVEIFSNYFSEQTALIQAIHDCEIVVIMRERTPFKADLLAQLPNLKLLITSGMRNASIDVAAAQAQGVVVCGTASRSEPPAELTWALILGLARQIVPENLALRTNGPWQQSVGMDLAGQRLGLLGLGKIGSNVAKVAQAFGMDVLAWSQNLTAERTQALGVQLAVSKEQLLEQSDIVSIHLVLGERTHGLIGAAELQRMRRHAYLINTSRAAIVDQAALIQALEQGWIGGAGLDVFEIEPLPAQHPFRSLPNVLATPHLGYVSQRNYKAYFGEAIEDIQAFLAGAPIRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK4</accession>
    <name>A9AVK4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1452</name>
        <name evidence="4" type="ordered locus">Haur_1724</name>
        <name evidence="5" type="ordered locus">Haur_2054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1452"/>
    <dbReference type="EnsemblBacteria" id="ABX04096">
        <property type="protein sequence ID" value="ABX04096"/>
        <property type="gene ID" value="Haur_1452"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04367">
        <property type="protein sequence ID" value="ABX04367"/>
        <property type="gene ID" value="Haur_1724"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04695">
        <property type="protein sequence ID" value="ABX04695"/>
        <property type="gene ID" value="Haur_2054"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1452"/>
    <dbReference type="KEGG" id="hau:Haur_1724"/>
    <dbReference type="KEGG" id="hau:Haur_2054"/>
    <dbReference type="eggNOG" id="COG3039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028885_2_0_0"/>
    <dbReference type="OMA" id="AKENCVE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1474-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="55"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="404"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="566" mass="63806" checksum="DF87C7D0933A3F4F" modified="2008-01-15" version="1">MTMRAALFGDYPIPEDTVELAHAIAPHGNRLMHLRDHFGMLFDNQQFSTLFSHTGQPALAPARLAMVTILQFMEDLPDRQAADAVRMRIDWKYVLGLPLADRGFDASVLSEFRARLVAGDGASILFETLLERLRDYGLLRTRGQQRTDSTHVLAAVRGLSRIECLGETMRATLNALATVAPAWVRCQIPPPWFDRYGPRADAYRFPKAAADRQRLAEQIGADGFELLTLLAAPTAPRELHVHPAVCILRRVWWQQYHAPNGPVRWREVADMPPSRMRIHSPYDRDAQYSTKRNMEWTGYKVHLTETFDADLPCLITHVLTTPSTIRDGEVLDQIHEGLARHDLLPSTHLVDTGYTDAAAMLTSQSTYGITLCGPIARDSAWQAKDPTAFDITRFQVDWDAKVVICPQGHASTKWISHQDRHGNPAIRVTFRPRDCRACPVRTQCTHTATAARGLSLRPREQHEVLQQRRHAQTTDAFKRQYAKRAGVEGLMSQATRVCGMRQSRYGGMAKTRLQHVLTACALNLLRSVAWVTGGSRHQTQTSRFVALRPPPALSQIREQTRLHSHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ7</accession>
    <name>A9AVQ7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4025"/>
    <dbReference type="EnsemblBacteria" id="ABX06657">
        <property type="protein sequence ID" value="ABX06657"/>
        <property type="gene ID" value="Haur_4025"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4025"/>
    <dbReference type="eggNOG" id="COG1479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011736_1_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4067-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="2">
        <location>
            <begin position="7"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="3">
        <location>
            <begin position="441"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="619" mass="71740" checksum="9564FDE2A2C0245E" modified="2008-01-15" version="1">MNKKTLTSLFAESIYQIPDYQRGYAWEEKQWKDFIQDIDALVDEQVTSHYTGTVVVYEGRDAEKRPYGRKKLKVLDVVDGQQRLTTTCLYLSVIIRALIQHGESDYERDIDDFLYAGATCKLNLNNETGDIFYDLLKTGYVNTPLQSPHQHRLVEAHRRFQHHISEQLQQRGGAGVAYLKELHYAITQKLNFTFYVIESEAEIGMTFELMNSRGKDLSVLELLKNYLMHWVSRNENNLADRETLTKLINRSWKDTYTNLGASSGNNEDQCLRIAWTLYCSHSPANWHGYEGFKADEYIPLRTFSKRTKAETKIFIEHFVMGLAEVSHHYASIINPTTTTALFEAERIWLSKIRHTGNIANFLPLMVAARKQYQAGQISEGAYIDMLKALECYAYRVFLWAARRSNAGKSSFYRWGYEIFTQPQLISDITRGIHQLTRYYAPEDDFINGNANPSDWYRTRNRLRYTLFEYELHLLATEGKNSEPRLGWDQLSDSTIEHILPQNPAKHSHWNGVWNKTAFNASVHDIANLVLTHNNASYSNFEFARKKGQPGLSPSYSDSDIRQERKLAAFADWTPKEFAERRNELIIWINQRWKTVGEPDNATLEVNDEADDDGIEHQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR2</accession>
    <name>A9AVR2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4030"/>
    <dbReference type="EnsemblBacteria" id="ABX06662">
        <property type="protein sequence ID" value="ABX06662"/>
        <property type="gene ID" value="Haur_4030"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4030"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_1_0"/>
    <dbReference type="OMA" id="DPHIWFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4072-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731664" evidence="5">
        <location>
            <begin position="24"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="305" mass="32780" checksum="A5C53640D53EA7A0" modified="2008-01-15" version="1">MQRKNLLVLLVLLLVSCGPSSFAQQTSANPPLRVAATVGMIADVVKHVGGEHVEVLGLMGPGVDPHLYKPSVGDVRILDDADLIFYGGLELEGRMTDMLEKLNRQKPTIAVTSQIDQSRLHATGGESFDPHVWFDVILWRDTIAIIVETLASYDPAHAADYQRNAAAYAQELTALDEEVKALIATVPSQSRVLITAHDAFGYFGSAYGFEVRGLQGLSTASEAGAGDVQSLAEFIQTRQIKAIFVESSVPQTTINAVQKAVQSRGWDVAIGGELFSDAMGDAGTEEGTYIGMVRHNVTTIVNALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVT1</accession>
    <name>A9AVT1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.79</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Haur_4049</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4049"/>
    <dbReference type="EnsemblBacteria" id="ABX06681">
        <property type="protein sequence ID" value="ABX06681"/>
        <property type="gene ID" value="Haur_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4049"/>
    <dbReference type="eggNOG" id="COG4021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044271_3_1_0"/>
    <dbReference type="OMA" id="WKQHTEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4092-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="PTHR12729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Thg1" evidence="12">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1C" evidence="13">
        <location>
            <begin position="134"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ABX06681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="252" mass="29629" checksum="CF448C349454648C" modified="2008-01-15" version="1">MNFDQLDQLMRVYETSNDLAVLPNIWMVVRIDGRSFTRLTKDVMNYQRPFDQRFRDAMISTVKHLMECGFPVLYGYTQSDEISLLLSYGCDVFGRKLRKYCSILAGESSGHFSLAIQQQASFDCRICQLPTDQLVHDYFRWRMEDAHRNALNAYCYWSLRDQALDPQTAHMQIANLSVAQKNELLFQHGINFNDLVAWQKRGIGFYWQTVDLQGYNPQTQMPTLTKRRKIHVEFELPQREAYSNLLASHFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW09</accession>
    <name>A9AW09_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Death-on-curing family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0599"/>
    <dbReference type="EnsemblBacteria" id="ABX03247">
        <property type="protein sequence ID" value="ABX03247"/>
        <property type="gene ID" value="Haur_0599"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0599"/>
    <dbReference type="eggNOG" id="COG3654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115697_7_0_0"/>
    <dbReference type="OMA" id="LLAMIEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-608-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006440">
        <property type="entry name" value="Doc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39426">
        <property type="entry name" value="PTHR39426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01550">
        <property type="entry name" value="DOC_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14699" checksum="8A0B5CFE429F73BE" modified="2008-01-15" version="1">MTHYLGLTDAFMLQAMVIQHIGGIHGITEQGFEKLATALAAPQQTMFGEDLYPDTFSKAAALFDALIHGHCFSDGNKRTALLAMIEFLARNGYAFNTPDDDSLYDWILLVAAERGMDREQQAAWIAQRCEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW62</accession>
    <name>A9AW62_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2072"/>
    <dbReference type="EnsemblBacteria" id="ABX04712">
        <property type="protein sequence ID" value="ABX04712"/>
        <property type="gene ID" value="Haur_2072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2072"/>
    <dbReference type="eggNOG" id="ENOG5032TJX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146077_0_0_0"/>
    <dbReference type="OMA" id="HWDECEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2100-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="109" mass="12162" checksum="7C6BE3E956E7B6BE" modified="2008-01-15" version="1">MDHQIHEPHAHIHSAHCGHTRIHHDDHIDYVHNGHLHAEHEGHYDDHVIAISATNPAACAPVACACTHDDCGHEMIPHGDHVDYLYEGRLHHRHGDHCDDHGPVTVVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWD0</accession>
    <name>A9AWD0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2140"/>
    <dbReference type="EnsemblBacteria" id="ABX04780">
        <property type="protein sequence ID" value="ABX04780"/>
        <property type="gene ID" value="Haur_2140"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2140"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_1_0"/>
    <dbReference type="OMA" id="TEFHVYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2168-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="72"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="306" mass="33753" checksum="1879619D9F371611" modified="2008-01-15" version="1">MQLSIVAPELQRYVRRIPPLPLGSAWGRRFVRWLGSRIPAKQFDGVTIEQRNDLNPPVRIYRPTVCHSTAALFWIHGGGMIIGQAAQDDQWCATTAQRLGIVVVSVEYRLAPEHPFPAPLDDCLAGWQWLQQQATTLAIDPARVVLGGESAGGGLAASLAQRLVDLGTTQPLAQLLFCPMLDDRTTTKAELTAIEHFVWNNRKNVIGWQAYLATKPGIDAIPAYAVPARRENLQGLPPTWIGVGDIDLFYQEDRLYAERLQVVDVDVTFEIVAGGPHGFQNWAFASAIAQAFIAKAHAWIQTQIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG3</accession>
    <name>A9AWG3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4090"/>
    <dbReference type="EnsemblBacteria" id="ABX06722">
        <property type="protein sequence ID" value="ABX06722"/>
        <property type="gene ID" value="Haur_4090"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4090"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_2_2_0"/>
    <dbReference type="OMA" id="DIIVAWN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4134-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="188"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="30367" checksum="DECD6324181F37F0" modified="2008-01-15" version="1">MSLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGPDGTEYQAHVVGRDPSSDVALLRVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGIINAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEVVGLFTSGFAGGEPIAIPVAVLTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLVGDILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWG8</accession>
    <name>A9AWG8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4095"/>
    <dbReference type="EnsemblBacteria" id="ABX06727">
        <property type="protein sequence ID" value="ABX06727"/>
        <property type="gene ID" value="Haur_4095"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4095"/>
    <dbReference type="eggNOG" id="COG5305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_391675_0_0_0"/>
    <dbReference type="OMA" id="WHAQDAK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4139-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="61"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="658" mass="73000" checksum="4B5A0C9B3176D410" modified="2008-01-15" version="1">MPKHPTRSLSFGLLIIALGLRFFRLSSQSLWLDEGGTWSEATGRSWLSLFGDLFSPRQSYPLYHLLMKAWTSVFGDSELALRAPSALAGTLAVVLLYHLAWRLSTPTVAWVAAGLLAINPFGLWQSQDAKVYSMLMAAVLWSNRVLLDLLDQTKPKQVWLWFASVVLCLSLHRLALLQVLGQVLVLALHFRQAAWRKWLWLGFGLLSLGFVAGIMFGLRQDPNAPPIGRTIGAFQAAWLLLGRLSFDRSSSDLTWRLLPVGLALASGLWLTWSHPRRNIILSLWLLPTLLFLAVLAAGSPLYEPRYLSFSLPLFCLILALGLAGIAQQRWLSAGSIVAITGLSAWLVFQQPYGIWSGNAVKEDYRGAVQSLAEHVAPDDVIIVQPPYIATLYQYYASRVTPDALPIARGFGRIGAIGYDQGEFDNDYAALLAGQRRGWLLIAPENAKAIDPPNPQYPQDDMGKVGINFLTADLNDKWRCTDLPYWEFNALRILCQSFPRPMQVENLALVGTWPIPKSATATWDNSLQLEGYQFQAWADGYQAGGTLPVQLAWRTNNVLVKDYRLFIHLVPALGAPVAAQVDTMPLNGGLPTSRWQANQAIHDQVSVPLPKNLAKGRYLVVLGWYDPTITEVAAQRLPVTASTAQHRANYIELGTVEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP4</accession>
    <name>A9AWP4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Na-Ca exchanger/integrin-beta4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03295">
        <property type="protein sequence ID" value="ABX03295"/>
        <property type="gene ID" value="Haur_0647"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0647"/>
    <dbReference type="HOGENOM" id="CLU_670435_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-658-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734385" evidence="3">
        <location>
            <begin position="24"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="292"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="410" mass="45147" checksum="1C0F36625D995E19" modified="2008-01-15" version="1">MRSIRYAIILFAIVILLPQKMSAAVAVDPPYYTGTSYNDNSLSLTYQGTWENVLNTGTYPYLGGYHKGTVGSSVQFAFNGNTITYMYETGPAFGKAEVFIDNKLVEIINQNSLYSKSQVSQSWTLSAGNHTIDIKLANGASGYFNIDAFIVDILPTNIVTPSWLDNTTTILMYQGALSGINGATGAIQNTLLEMSSGRGWWVITPAQSFTYYYTQSPNYDKVVITVDGEEIGIIDQESQNQVHQKWINFDIDANGKKFHTIHVMTIPNSNNQILNTTNLDALTFNPALDTETALSIEQNTYTVREGNTLQVKIKLSTAVSYDVSVAYKTTSLSAVGCNINQCDSIDDYINTQGSVIFSAGQTEKVVSIPITTGDVTEGTEFFALNLYSPSNASINEQNRYTRISILNRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWQ1</accession>
    <name>A9AWQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0654"/>
    <dbReference type="EnsemblBacteria" id="ABX03302">
        <property type="protein sequence ID" value="ABX03302"/>
        <property type="gene ID" value="Haur_0654"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0654"/>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027398_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-665-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="472" mass="52663" checksum="5E34B018A710EAC5" modified="2008-01-15" version="1">MLPYAHDPVAYAREVLGEVWWTKQELIARSLLTPPYRTLVKACHKVGKTHLGGGLVNWWYDSFDPGLVLTTAPTDRQVRDLLWKEVRMQRRGRAGFTGPKSPRLESTPDHFAHGFTAKDGDSFQGHHSPHTLFIFDEAVGVASVFWETAESMFNEGGAWLAIFNPTDTSSQAYAEELSGGWHVISMSVLEHPNILAELQGLPPPFPSAIRLSRVDTLLKKWCRALSPEEPKRATDIHWRDAWYRPGPIAEARLLGRWPSQATNNVWSDGAFQVAESLLLPASDEPCELGCDVARYGDDFTEIHVRRGGHSLYHEAANGWSTVETAGRLKQLANEYGRRCGVDGRAVAVKIDDDGIGGGVVDLADGYTFLGVSGARTAYDPEKYPNRRSELWFSVAERAMEQRLSFVALDAETRRELRRQAMAPTWKQDSQGRRVVEPKADTKKRIKRSPDGMDAVNLAYAPAPIVSFGPSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWX6</accession>
    <name>A9AWX6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0729"/>
    <dbReference type="EnsemblBacteria" id="ABX03377">
        <property type="protein sequence ID" value="ABX03377"/>
        <property type="gene ID" value="Haur_0729"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0729"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741234_0_0_0"/>
    <dbReference type="OMA" id="ICDWIMP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-741-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="364" mass="40137" checksum="01007CF606260C48" modified="2008-01-15" version="1">MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLMLETVPRLPGWEMSAVSLPARELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTVFRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDPQTGMMHLANAGHNYLIVINNQVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLLQAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPITADEWWQALSLVGTTRTPDQCLELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQSTKGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX14</accession>
    <name>A9AX14_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2182"/>
    <dbReference type="EnsemblBacteria" id="ABX04822">
        <property type="protein sequence ID" value="ABX04822"/>
        <property type="gene ID" value="Haur_2182"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2182"/>
    <dbReference type="HOGENOM" id="CLU_677516_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2210-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731692" evidence="1">
        <location>
            <begin position="21"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="406" mass="43355" checksum="6DC8C6FFC55A85C5" modified="2008-01-15" version="1">MRWMLLLLSACWLIACQSQQSLPSAPTRITIGVAPTSVVGADLPILLEVEPNWNGLVNLTMQTSYAVHSQAVTIVNGQGTTSLISPWNEQRGDVTIVAQVGQVQARATTSFQPGMVVEPLRPLVGARSIIANGATWSMVVVIPHDQFGNPIADASAVDITAQRPNQQLTRITVKTAHLLAWQRLYSQTVAGKTLISATSQDRLGPQAELLEVAGWPVDISIQLGQLPTRISADGHSFIPVQTNLIRDAFGNVMPDGTSVVFEVNDGTGLKRLINSVTIRGVAEAQILSPNQATTLTIQARIFRVASEPLIVDVPPNGGFDFALQAVVATDVISITAGPISGSLQQYVPDGTIAVLQVTGPARFEQTSDVVAGYIQTTIRRSLLPAGRYTLICRVGDKQAKLLLVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXB5</accession>
    <name>A9AXB5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver and ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4203"/>
    <dbReference type="EnsemblBacteria" id="ABX06835">
        <property type="protein sequence ID" value="ABX06835"/>
        <property type="gene ID" value="Haur_4203"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4203"/>
    <dbReference type="eggNOG" id="COG3707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_65_0_0"/>
    <dbReference type="OMA" id="QKTSMDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4250-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008327">
        <property type="entry name" value="Sig_transdc_resp-reg_antiterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036382">
        <property type="entry name" value="RR_antiterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="125"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="21834" checksum="55B595EAC3EB413E" modified="2008-01-15" version="1">MPQTRIVIADDESLIRMNLRETLVGLGYLVVGEAGDGVSVINLARELRPDVVVMDIKMPKLDGIQAAKVLTEEKIAPVLLLTAHSDKELVERARDAGVVGYLSKPFRDSDLMPALEIARARFEEFLTLEQQVGDLKETLETRKIIERAKGMLMDSQGLKESEAFRKIQQLSMNTRKSMREVASALLLANQMEQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXG1</accession>
    <name>A9AXG1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M14 carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4249"/>
    <dbReference type="EnsemblBacteria" id="ABX06881">
        <property type="protein sequence ID" value="ABX06881"/>
        <property type="gene ID" value="Haur_4249"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4249"/>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028657_0_0_0"/>
    <dbReference type="OMA" id="YDPNRDW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4296-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="9"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="557" mass="62732" checksum="F090CA7BD2F6B428" modified="2008-01-15" version="1">MPEIDYTRYYRFAELVEALEGFAAEYPDLISLQSIGKSYEGRDLWLATVTNVATGGPREKPAFWVDANIHASEVTGAMAGLHLIDTLLKGYGNDAECTRLLDRTTFYILPRFNPDGAERALTTPYVVRSSVRPYPYAERIDGLYQEDINGDGIILQMRLVDPNGDWRVSEHDPRVMVKRKPYEIGGTYYRILPEGLIQNYDGVNIKLSRAVEGLDINRNFPVDWRPEAEQYGAGPYPTSEPEIRAVVQFIVDHPEIHSGLTYHTYSGVLLRPYGDRADDQMNLHDLDVFKALGKHGTELTGWPSVSVYHDFRYHPKDVITGVFDDWVYDHLGMFAWTVEFWDLVGSAGIKDRKFIEWFKEHPEEDDLKIMQWVDEHGEGLCFYDWTAFEHPQLGPVEIGGWHPMYAFRNPPPAKLLETIAPVTQFALAHAAIAPFTTISSFELEALGDNVYRLQAVVQNEGYLPSYGSQKGRERKATLPLEALLNLPEGSSLKLGQAKTTIGDLEGRSGRVSFFGFSNGSTTDRTKVEWVVHVPNPGVIELTIQGGRGGIARAKLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXV6</accession>
    <name>A9AXV6_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0749 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2282"/>
    <dbReference type="EnsemblBacteria" id="ABX04922">
        <property type="protein sequence ID" value="ABX04922"/>
        <property type="gene ID" value="Haur_2282"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2282"/>
    <dbReference type="eggNOG" id="COG3879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040273_0_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2310-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010273">
        <property type="entry name" value="DUF881"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37313">
        <property type="entry name" value="PTHR37313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05949">
        <property type="entry name" value="DUF881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26357" checksum="4A877CB7F705A13C" modified="2008-01-15" version="1">MNRFRIRRGILRQSLLTLMCMLIGFAVVTQLRTYENIANDVVKLSPEQRAELMISLIDRNAATEREIIALRQQNEDYRRTQSNGTSTLDQLANDLNRYKLHTGAVQVQGGGVTITINYPLRAADVIALTNEVRNASGEAIAINGRRIVARTRIEEDDNAELYLDGQIQHAPYTIQAIGDKETLMGALNRVGGLLRIWNEIDGVDITIEPTNVITMPRVSNQPEFRYAQPAPKEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY19</accession>
    <name>A9AY19_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4269"/>
    <dbReference type="EnsemblBacteria" id="ABX06901">
        <property type="protein sequence ID" value="ABX06901"/>
        <property type="gene ID" value="Haur_4269"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4269"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408752_0_0_0"/>
    <dbReference type="OMA" id="WFHILAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4321-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="457"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="647"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="678" mass="76303" checksum="E8B64D9E08207B95" modified="2008-01-15" version="1">MQLVGSTLFRDRSSIFAEPWRVWLAAVGGLVLWAVLLLTITYQWQAQATITLGDYYDPPFLQGNFSPGEVSQGNNRSFRWTTGEATLAVPLAGRGSWTTKIDLLTQHPDASPVEATLNFAPNVAVALPDSNETRIIHAFIPATATSNGNLAIGLNSNLYQEQTASARTLGVALFNVELASTTGRPWLPPLLAVVLLSIILLGIAASILLTGINWTWAVGLSAALGVGLALPVMLARVPHTFWLPNLAVLAVLSVGLVAALRKIVPWLMHKGGIELEPRTLTILLGLFLFGFWVKAAGQVYPYMIAIDIHWHMERVRWILDGRLAEMYKPGAFNESVMPEKEFGKDRPIIPYSPFFHIFATSFALLPFQMETTAKIFSSIIDSSYIFLIYFFARSFDFSRRVGLLAAAFYNVVPLTYLLHSWGNVPTTFGMWWTFMSIAFVIGAWGKLDQRKVWWSFAALLTVAFLMYTVMAVFLGLLLCIWMSYIAITKRSERRQARSVITAMLVGVLGSTIVYYGLYIPGIIEKTIPYFTTTFTEGQEAVGAIQYQPTAYDNFLAYRTRLWNHGLMIPFLLLPFALWVIARLRTRQPETRLWMGSIWMCAMVTVSLLFTVIDRNVPMVDKHIIFLIPVWAILMAMLMDMALKRWRWSSILFGLAYLGLFAMSIELWTRRIATVKQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY78</accession>
    <name>A9AY78_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol alpha-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4328"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06960">
        <property type="protein sequence ID" value="ABX06960"/>
        <property type="gene ID" value="Haur_4328"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4328"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_1_0"/>
    <dbReference type="OMA" id="ANSKACH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4381-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="194"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="41673" checksum="3319CCD42D929D2E" modified="2008-01-15" version="1">MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSIPTYGSGSSTSLPICIESNRRLREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFHIRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETAQAIFGTKDEYTIIASGITIDRFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGPLREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGLPVVAAANAGYAGVLANHPGNLAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYSWQVIGDQIMEFYKKTMAQTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD9</accession>
    <name>A9AYD9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine dioxygenase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0873"/>
    <dbReference type="EnsemblBacteria" id="ABX03521">
        <property type="protein sequence ID" value="ABX03521"/>
        <property type="gene ID" value="Haur_0873"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0873"/>
    <dbReference type="eggNOG" id="COG5553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1335999_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-887-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="PTHR12918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="23086" checksum="157FCC4ED6D7970B" modified="2008-01-15" version="1">MMKPLELIQAIRMIKRQALAQSTQLAQLRQALIAFVSEPANRQVNLTNTSCGLYTRILLNSFDDDFQIVVVLWGPQSASPIHDHNGTVGAVAALAGHTIEAKYQILRTEAQRAWLQKQETSVLEATYVTPILPDETSQLHDMVNATDTWAATVHIYLTPITDFYIYEPQPDGTYIMVERKLWFDGDNAWQTWQTPLQQEVLGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE2</accession>
    <name>A9AYE2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0876"/>
    <dbReference type="EnsemblBacteria" id="ABX03524">
        <property type="protein sequence ID" value="ABX03524"/>
        <property type="gene ID" value="Haur_0876"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0876"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1757940_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-890-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="17624" checksum="64C89C51EED6932E" modified="2008-01-15" version="1">MADSQSVPPIELVTYINVVPARVYETLTTGAGWDAWFTQGTTIDPRPGGKIHLRWQNFGAGRWTAEDGGPVLEALPAQRFVFQWSPSGEPTTVAFTLKPLGTGTFVHLVEQGYKQTTSSLQACLGCATGWGEALTLLKFYLEHGITYGTVPPAAAELVAIQAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYK7</accession>
    <name>A9AYK7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2345"/>
    <dbReference type="EnsemblBacteria" id="ABX04985">
        <property type="protein sequence ID" value="ABX04985"/>
        <property type="gene ID" value="Haur_2345"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2345"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_0_0"/>
    <dbReference type="OMA" id="GKQMRPM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2373-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="35236" checksum="8918B9E20F444E12" modified="2008-01-15" version="1">MTHTLKQLEIPSTLRHDLQAVEDRIMQRVESQSALITAAGQHIVSSGGKRLRAMMVLLASQLGRYRLSDSLHAATAVELIHAASLVHDDLVDDADRRRGKVTVHAKWDQGVALMVGDYLFAVAAGEMALAPDPRVIQIFAESVMTISASELHPVMATLPTATALEQYYAKIGGKTAALFEAAAAAGVVCGGGSPEEIEAAARYGYDIGLAFQIVDDILDFVSTEETLGKPAGNDLREGTITLPLILAVKDHHEHPLVNLLDQYEQLSDEQVTQAISQVKQLGGIDQAIAQAREITQRGLAALDIFPPSDAKELLREIADYVLDRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2020-12-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ08</accession>
    <name>A9AZ08_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="12" type="ordered locus">Haur_4416</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4416"/>
    <dbReference type="EnsemblBacteria" id="ABX07048">
        <property type="protein sequence ID" value="ABX07048"/>
        <property type="gene ID" value="Haur_4416"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4416"/>
    <dbReference type="eggNOG" id="COG0595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_3_1_0"/>
    <dbReference type="OMA" id="KNTCVFE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001587">
        <property type="entry name" value="RNase_J_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01292">
        <property type="entry name" value="UPF0036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="18"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="363"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="569" mass="62035" checksum="70739D62D8CA0A2C" modified="2008-01-15" version="1">MTKNKLRVIPLGGASEVGRNMWVFEYEEDIVICDMGVMFPESEMMGVDLVLPDITYLRDKVANIRGILLTHGHEDHIGAVPWLIGDLGFPTVYGTTLTLGLLSNKLKEHRLTDKVATKVIAPGDKFQLGCFTIEPFHIAHSIPDSVGFGLTSPAGLALYITDWKLDHTPVDNWPTEIDRLVDFGRRNPIVLVTDCVRVESKGYTPSERVVGDAFDQIFATAPGRVIMATFASNISRVQMAINAAIDYGRKVVPVGRSMENNTSIARELGYLEVPDGTLIRAGDMKNLPDDQIAIVCTGSQGEPMAALSRMANRDHRQISIQRGDTVVISASPIPGNEVSVYKVIDNLYKLGANVIYGSDLPVHVSGHAAQEELKMLLNLVQPQYVIPFHGDYRHLARYKQLAEGMGFNGDNVLIAEGGSIMEFSQNYGKLVSRAPVGHVFVDGVSVGDIGGAVVRDRQMLSKDGILMVVVSVDLQTGNLVAGPDIVSRGFVSTRDSTDLIEGAKEAVRASFSESYVVPARAFSDGEETAEGNSPAVSSPAARKIKEVVGRFLYERTRRRPMVIPVVMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ12</accession>
    <name>A9AZ12_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4420"/>
    <dbReference type="EnsemblBacteria" id="ABX07052">
        <property type="protein sequence ID" value="ABX07052"/>
        <property type="gene ID" value="Haur_4420"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4420"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_0_0_0"/>
    <dbReference type="OMA" id="WRETSYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4475-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="149"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="29751" checksum="225167BA32355DB4" modified="2008-01-15" version="1">MTNYYEMFKQHEESIVETIITTLQTQIPTYGKISRDDVRKRVIAGLDPYARDLDTEHPKAFPDYWRETSYLRAQQGIPIGDFLQVLLLSTDIMIQGLRQAYPDSTADQINVIEKGHQITTAAIAAVYEGFQQHKDEIISSQTYALAEVSSPIVPVYEGVLVLPLIGSIDSMRAGQIMESLLESINTYSADVVILDITGVPVIDTGVANYLLQSARAARLLGSTVVLVGIGAEIAQTIVQLGIDLTGIVTRANLQSGIEYALDLQGLAIRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ88</accession>
    <name>A9AZ88_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0986</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0986"/>
    <dbReference type="EnsemblBacteria" id="ABX03634">
        <property type="protein sequence ID" value="ABX03634"/>
        <property type="gene ID" value="Haur_0986"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0986"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329221_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1002-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="539"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="619"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="683"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="360"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="872" mass="100186" checksum="4D5FBB0A3AACD150" modified="2008-01-15" version="1">MSFLQQSDADAVPTIALGQPATPWQLALNQFVTLVANESLGGESLPHYFKPWLTHLTTWLLFIPTDPKTLLQGFVLGQADRYQLLAQATRLAWLEQYYFSAPQALLAPQRLAKPTEFGLPLPSTNEPVWLIPLRAYGRLWGIVVLEVAEASPPSEHPLYVMVAQAIANLSLHLDARYAREYEVQAYQRMQMMSESSHILAHTGLNLDRMLMALSKHLCQHFSDGCMIQILSMSQPSQIQQEIFHHQQTDYRTQLYRMSAEWADQLAPDSLRYQVLISNQPLALNIYEHQLLLEASEFQPLLGEYKLHSVLMVGLYWNEHPVGILSLLRTHINLPFMQEDLEIARDIGTRFVEALEQTRLYAELREQEQALMLMVRRLEEQVEERTNELSNKNVQLNRELDRRRKTEEALVESQALLRSFYASTPVMMGVVEITPEADLVLLTANTMTVKQWQLAASYAEMTMSQLGIPQADIDRWIQYFQRSRTKGQPERFDYNDPFDSNIIYTATIGPVNTASPIGQRFCFVLEDITASRNLQQSLEESKHLVEQINASIPCIVYKYDVKLNQITYINRSLESMLGYGTNEMLEMQEMDLRSLIHPDDLIQIDAYLPSLYTSKPGTIIQNRFRIKHRDGQWRWIIGYDTVFQTDETGYASSILSALQDVSELYSHREQLQASLEEKMVLLQEIHHRVKNNLQIVSSLLNLQARQISDPNTRDRFLESQSRIHAMALVHEQLYRSSDLRYIDLAEYIKHLVQFFRRSHTNRPTLSINIQIEPVNLNTDTTIQLGLIINELLTNSFKHAFVAQETGLIWLKGSYDQQFVELEIGDDGIGMPTDRQPSNSMGLELVHALIRQLGASIQQLSTDGTVFKLTIPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD5</accession>
    <name>A9AZD5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional activator, TenA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2439"/>
    <dbReference type="EnsemblBacteria" id="ABX05079">
        <property type="protein sequence ID" value="ABX05079"/>
        <property type="gene ID" value="Haur_2439"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2439"/>
    <dbReference type="eggNOG" id="COG0819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077537_3_0_0"/>
    <dbReference type="OMA" id="FYIIQDY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2467-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034641">
        <property type="term" value="P:cellular nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046483">
        <property type="term" value="P:heterocycle metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901360">
        <property type="term" value="P:organic cyclic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="1">
        <location>
            <begin position="11"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="209" mass="23521" checksum="7B5B37F57708EB64" modified="2008-01-15" version="1">MVFMDYAANFWQANRLLAQACLQHPFVQGLATGQLSVERFADYIGQDSFFLQSFARAYSLAAAKAPNWASVCTFHQLAGGVIQELQLHQAFAADWQVDLNVVQPNPATQRYTDFLQLTAWSSDLGTLAAAMAPCMRLYAYLGQNLASTQAASQRYSAWIETYSSNEFEALVRQLEQLVNQHSYNLASAAQAYRYAMQCEYDFFEAVWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A9B015</accession>
    <name>A9B015_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1074</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03722">
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        <property type="gene ID" value="Haur_1074"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1074"/>
    <dbReference type="HOGENOM" id="CLU_1967519_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1091-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14798" checksum="B126FA195496EAC5" modified="2008-01-15" version="1">MLQTFLSAELTDQYYLLQACIDFETSLIVSQTHTVLKTLLAILDRPYAAAPELGLVGIGCVMLTQKNLTIKLCFTYVDYDEYQHHQRVNFVFHLLAIIGQQFPFAQNQFYDILKFWLDAYQTEYLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0B4</accession>
    <name>A9B0B4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2585</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2585"/>
    <dbReference type="EnsemblBacteria" id="ABX05223">
        <property type="protein sequence ID" value="ABX05223"/>
        <property type="gene ID" value="Haur_2585"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2585"/>
    <dbReference type="HOGENOM" id="CLU_1048757_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2613-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29566" checksum="0E6C2CB80BA8AA17" modified="2008-01-15" version="1">MDGLILERNEFLVLLEAARTNKIIGLDNETLVPHDQATHLAALNQGVQGLVAKELATINEDEVVMIEREILEFSQIVAFPDIAFITTRDTPNVGSQLFLHYVNQLGVVEQTLPNEQQHRLAFLPDMLVLFDRLAFLLEVQPSKAFEASVRLSQSEFMAIKELAENRAEAEAFNRLSRAGLDEQAAQALIAAIQAPIFSASLAILRCEDTEIVDAINPAILQGPTSAWAIQLDEADLETFEVQSIDQTWLRQHIQHWFEQLATAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J4</accession>
    <name>A9B0J4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4581"/>
    <dbReference type="EnsemblBacteria" id="ABX07212">
        <property type="protein sequence ID" value="ABX07212"/>
        <property type="gene ID" value="Haur_4581"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4581"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_7_3_0"/>
    <dbReference type="OMA" id="HTRREGT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4636-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="15022" checksum="4605D07AFE422FE3" modified="2008-01-15" version="1">MVEHEDGINPAMVERGRQMLHDDESYFLMAETFRALADSTRVKIVGCLLEQELCTADLAAILNYSESAVSQHLRVLRQLRLVKQRREGKLVFYSLDDDHVRVLVLVCLNHIRHGSTPDPSVAPILAVLEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0K6</accession>
    <name>A9B0K6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4593"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07224">
        <property type="protein sequence ID" value="ABX07224"/>
        <property type="gene ID" value="Haur_4593"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4593"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_1_0"/>
    <dbReference type="OMA" id="HRILFFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4648-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="26493" checksum="C47E7DDA226A0937" modified="2008-01-15" version="1">MMLLSVLIPCYNEAATIANMLERLAQITIPMQWIAVDDCSRDDTYQVLQQLTATYPHMQVVQHRQNRGKGAAIRTALAHATGNIVIIQDADLEYDPHDFYELIKPIEAGLINVVFGSRFMGRHTGMYFWNAIGNKGLTFLTNLLFNCWISDMETCYKVMRTDIMRSMNLVSNDFRIEAEITAKVLMQGERIFEVPITYLGRTYEEGKKMHPKYGFLTVWALFRLRLLGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0W6</accession>
    <name>A9B0W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1188</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1188"/>
    <dbReference type="EnsemblBacteria" id="ABX03836">
        <property type="protein sequence ID" value="ABX03836"/>
        <property type="gene ID" value="Haur_1188"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1188"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_534075_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1210-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732310" evidence="7">
        <location>
            <begin position="22"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="468"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX03836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="541" mass="57201" checksum="A3BB7C58183F6687" modified="2008-01-15" version="1">MSRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTVAVIDSGVDMNHPDLVDVLRTDGFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVAGGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINMSLGSMLPLDSEDIVEAIKEADAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGIYSTMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAEIEKTADDISAQNPIKRYGPITYFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLIMLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAPPPPIHYDQAMAQQQRNLASQPIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAISGDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B136</accession>
    <name>A9B136_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2676</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.6.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2676"/>
    <dbReference type="EnsemblBacteria" id="ABX05314">
        <property type="protein sequence ID" value="ABX05314"/>
        <property type="gene ID" value="Haur_2676"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2676"/>
    <dbReference type="eggNOG" id="COG1564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044237_1_1_0"/>
    <dbReference type="OMA" id="ITYCPEG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2706-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="SSF63862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="SSF63999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPK_B1_binding" evidence="6">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="217" mass="23325" checksum="8F5E44D650B2D95D" modified="2008-01-15" version="1">MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLEIMQARKVEIQRFPAAKNETDLELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPALIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDVAGVRTEGLRYPLRDEDLPIGPARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B149</accession>
    <name>A9B149_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2689"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05327">
        <property type="protein sequence ID" value="ABX05327"/>
        <property type="gene ID" value="Haur_2689"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2689"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023845_4_0_0"/>
    <dbReference type="OMA" id="ARHIYSA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2720-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="36409" checksum="48593ADAF46C04BD" modified="2008-01-15" version="1">MNCSIIILNWNGRALLADCLNALLPQCDASIEVLVVDNGSHDGSAAWLHQHYPQVRLLALTNNRGFSGGVNVGLHVARGDVLLLLNNDAIVEPNFISAILAPFQHQPTLAASAGLMTFAHRPEIIASAGIQLYRDGVATDAGLLQPVAQLASQPSPIWGGSGGAVAYRRAALADVGMFDEGYFAYLEDVDLAWRLQLREWQTVLAPQAVARHIYSATGGEGSPFKDWLIARNRWRVILRCWPTPLLARALPLMLAYDGLACAQAIVRRRWTTVSGRLHALRQLPQLRQQRQAIQARRTASIAELDHWIKPARSPLAIWRENQALGQLIAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B161</accession>
    <name>A9B161_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2701"/>
    <dbReference type="EnsemblBacteria" id="ABX05339">
        <property type="protein sequence ID" value="ABX05339"/>
        <property type="gene ID" value="Haur_2701"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2701"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1341274_0_0_0"/>
    <dbReference type="OMA" id="AVICQAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2732-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="19020" checksum="5F744978676F0C5A" modified="2008-01-15" version="1">MAQAQLLYIGTEQGVVLLSNPGRIDRWISVGIELADQAIAAVICQADAPMQATVWNSNQAWQTKDGGQSWQALEPAPSLIAPSQSIELTGQPPATIRIASDPNQLERSSDGESWQHLAIGQVGEWSCLISVAYQIDSIYAATKAGQVWVSSDRGRTWALLKQQLAPITALAIGRVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1D1</accession>
    <name>A9B1D1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isopentenyl-diphosphate delta-isomerase</fullName>
            <shortName evidence="6">IPP isomerase</shortName>
            <ecNumber evidence="6">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl diphosphate:dimethylallyl diphosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Type 2 isopentenyl diphosphate isomerase</fullName>
            <shortName evidence="6">IDI-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fni</name>
        <name evidence="8" type="ordered locus">Haur_4687</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homooctamer. Dimer of tetramers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IPP isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4687"/>
    <dbReference type="EnsemblBacteria" id="ABX07318">
        <property type="protein sequence ID" value="ABX07318"/>
        <property type="gene ID" value="Haur_4687"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4687"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065515_1_0_0"/>
    <dbReference type="OMA" id="WDWGIPT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="IDI-2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00354">
        <property type="entry name" value="Idi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011179">
        <property type="entry name" value="IPdP_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43665">
        <property type="entry name" value="PTHR43665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003314">
        <property type="entry name" value="IPP_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02151">
        <property type="entry name" value="IPP_isom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="10"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="176"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="68"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
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        <location>
            <begin position="294"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="344" mass="36086" checksum="8738E219737F3A2D" modified="2008-01-15" version="1">MTETATEGRKIDHVNIVIKEDVNAKGITTGFGRYHFEHDALPELDMRRIDLSTTFLGKQLKAPFLISSMTGGAAPTEKINLQLAEAAQALGVAMGVGSQRAAIFDPSVAASYQVRRVAPDIALFANLGAVQLNYGYGVEQCLRAVDMIQADALILHFNALQEAVQPEGDTNFAGLLQKVEAICRALPVPVIAKEVGNGIGAKTAKRLVEAGVQAIDVAGAGGTSWSEVERFRHRTQAGQRIAATFAGWGIPTTEAIKQVRAALPNIGIIGSGGLRSGLDLAKAIALGADLGASAAPNLLAQNDGGSEAVYEAILAVIDELRISMFCTGAANLAELRQTPLYSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1G8</accession>
    <name>A9B1G8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional activator domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4724"/>
    <dbReference type="EnsemblBacteria" id="ABX07355">
        <property type="protein sequence ID" value="ABX07355"/>
        <property type="gene ID" value="Haur_4724"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4724"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_1_1_0"/>
    <dbReference type="OMA" id="THARTFR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4782-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="94"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="713" mass="79689" checksum="52DCE548D4BE1ADC" modified="2008-01-15" version="1">MDLHCYFLGQPQIVYNQTAIHVTNAKAVALLAYLACHNQPQPRERILGLLWAESSSSAARKNLSNCLWQLRQQLGESCILSHDDRLSLGEAVWSDLQALWQLDQPDHATLLNCYRGPLLDGLNVRDAPEFELWLLHERNRLLQHYLQLLEQALQTTNDQQQKLQLANHGLGVDPLHEPFVQAAIQACLALEQRANALQHYTNFQHQLEQQLGLEPAAATQALRLQILGTSTNPTIKPPHLPTPRNTSKLIGREPDYALLHAAWQRSLQGQLQVVLLTGELGIGKTSLWQTWLGQIREGHQVVVARGLEITQLLPFAPFLAWTDQTALLDWLFGAQSPLSPYWQSELARLIPDFKQREIIPPLSNATPAEERRRIFEAMLQVLALFADQPLVLVLDDAHWADQLSLGWLGYAAERLQSKPVLIILTYRANQVQGELANLIWHWQRNHIAQRHELQPLSPRESEQLVLQQGGDQQRSAQLYRRSRGNPYFLHELLHAPSEQIPSSLADVVGLRLTNLPSAAQALLSAAMILGINSRLELLQQVSHCAEDQALDMLDLLLQQGILAEQAGQYQIAHPLIGEVWQQQLSPARRQVFHRRAAEALAESYAGMLPMVAVQLASHYEAAGKAHEAARYAEMAGYHALIMAAGSEAVVLYQRALTLEPTPLRQLGLGRAWVLQGDLAAARANFNAARQAFELLGDFEGAAQASLQLAASYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1H3</accession>
    <name>A9B1H3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1210"/>
    <dbReference type="EnsemblBacteria" id="ABX03858">
        <property type="protein sequence ID" value="ABX03858"/>
        <property type="gene ID" value="Haur_1210"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1210"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_549542_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1232-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="107"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="496" mass="53485" checksum="530D7EA917AD3247" modified="2008-01-15" version="1">MSGYADFELTINPKDAENSFVVHGRTAKGMQDSDSLILPVDDPRYQAFQTALDYNTPLTEDQVIDFGIVLYETLLKGKIWALFTAARETARSQGQSLRIKLNVDANNPALATVATIPWEFACDSAGIPLTTDHSICRFLTFPESVPVLSLGQEKLRIALVGALPAEMATTHPVDIQGELAAIHRSLEPLVTQNQVEIYEETQLTAPKLQRLVREWRPHIVHYVGHGDFQGTTGALILDDGNGKKHLSTARTLATLLRNTSVRLVVLNACKTSTVSSTALLRGIAPALMAANIPAVVAMQSSILDTAGKAFAEEFYRVLATGTPIDACVAEGRKSIIAYGFGQLDWGLATLYMRADDGVLFNIPTPSVPSNQVVTPTNETTPLANLTGGNSVSNLLGNNNTITGGNISIGNVVAGNHNQTTINHGVAQPNTPSAANNQQQALAAERELLALKQKNLNITKLQIEQYGIGVPVYLQNQHDELVKDIAAIQQRIAELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1R1</accession>
    <name>A9B1R1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1298"/>
    <dbReference type="EnsemblBacteria" id="ABX03946">
        <property type="protein sequence ID" value="ABX03946"/>
        <property type="gene ID" value="Haur_1298"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1298"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131559_1_0_0"/>
    <dbReference type="OMA" id="FLHINVL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1320-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14086" checksum="70EE012CBFCD2F82" modified="2008-01-15" version="1">MHALLSQLIVGTFPPLDLAQLRDQSELDGPLWSYTTDQLNLNLLRFRFGDGIPNHQNHEVDVLLIVLEGTAILEIDLVQQPIGVGSIVCVPRGAARSIQATSDELIYFSCHQRRAGLFPTITKHNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1T0</accession>
    <name>A9B1T0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2734"/>
    <dbReference type="EnsemblBacteria" id="ABX05372">
        <property type="protein sequence ID" value="ABX05372"/>
        <property type="gene ID" value="Haur_2734"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2734"/>
    <dbReference type="HOGENOM" id="CLU_1233655_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2765-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="234" mass="25262" checksum="B03A2B865709236B" modified="2008-01-15" version="1">MSNQLPPTTPIQPSNQPPANQPPGQWYGQQPYQATPQAYGNPTYSVPPQSVNATNSWLRWLGFNVLAMILSSVVFAVLFFILAIWLFIDGSQAGGIVDSINTQAGEVGFTIGLFATITGISGLVAGWIQRIGLHNRVSYGPWIFKTGLMTALTTAVSLAIFFFLINPNTSADNYQLINTLFLTASTAAIALATGLGQLSEVKKVSQQPFTWIIISVLTWTSLSGLAWGSFIFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B272</accession>
    <name>A9B272_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0135</name>
        <name evidence="3" type="ordered locus">Haur_4791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.49" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0135"/>
    <dbReference type="EnsemblBacteria" id="ABX02787">
        <property type="protein sequence ID" value="ABX02787"/>
        <property type="gene ID" value="Haur_0135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07422">
        <property type="protein sequence ID" value="ABX07422"/>
        <property type="gene ID" value="Haur_4791"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0135"/>
    <dbReference type="KEGG" id="hau:Haur_4791"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013584_15_4_0"/>
    <dbReference type="OMA" id="WVFGDRD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-138-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025960">
        <property type="entry name" value="RVT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13655">
        <property type="entry name" value="RVT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="94"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="560" mass="63685" checksum="111A332DF6E041E4" modified="2008-01-15" version="1">MMAETSAGAASRSEVEWHAINWQHVNQTVRRLQSRIVKATQAGRYGKVKALQRLLTHSFSGKALAVRRVTENQGKRTPGVDQVIWDTPEKKATAIRSLRRRGYQPRPLRRIYIPKKHGKRRPLGIPTMHDRAMQALHLLALAPIAETTADPNSYGFRSERAPADAIGQCFVALAKRKAPTWILEGDIRSCFDRISHDWLLAHVPMDKAILQKWLKAGYMEGTTLYPTEHGTPQGGIISPVLANLALDGLERILLEHCPRRTVRGIAAKVNLVRYADDFIITGRSRELLEQTVKPLVEAFLKERGLELAPEKTRITTIEEGFDFLGQNVRKYKGILLIKPSTASQRTFLATIRATIKANMALDAEKLIRLLNPIISGWTAYHHHVVSKAVFQSMGHAIYQALWRWAKRRHANKPKRWIKEKYFRPVNGNQWVFSGDSAGRPIRLVAAGYVPIKRHVKIRAAANPYDPAWEMYFETRLGVKIASTLKGRRQLLHLWKRQNGICPCCQEPITMLTGWHNHHVIRRIDGGTDTAENRMLVHPTCHTQIHSQRLTEVKPCLERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B279</accession>
    <name>A9B279_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4798"/>
    <dbReference type="EnsemblBacteria" id="ABX07429">
        <property type="protein sequence ID" value="ABX07429"/>
        <property type="gene ID" value="Haur_4798"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4798"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_1_0"/>
    <dbReference type="OMA" id="NWRPTFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4856-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="4">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="33734" checksum="96681773162B872F" modified="2008-01-15" version="1">MTQALCLGELLVDFVPTEAGLGVANTPLWQRAAGGAPANVAVGLARLGITSGFLGMVGADSFGDFLADTLAQHNVNIQGLRRTEQARTALAFVALQADGERDFMFYRHPSADMLFAPSDLDPRQFANVELLHFGSISASNDLGYQTTLRAIELAHANGAVLSFDPNLRAALWPSLEAARRVMLKLLPLAQIVKLSREEAEFLTALADPLAAAQSLWHERSQVIVVTDGSAGCWYQTAARSGHVAAPNVQAIDATGAGDSFVACLLAQLIQHPSLPADQTKFERALQRACIAGALATLVRGAIPGLPTAQQIEQFQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2C8</accession>
    <name>A9B2C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03973">
        <property type="protein sequence ID" value="ABX03973"/>
        <property type="gene ID" value="Haur_1328"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1328"/>
    <dbReference type="HOGENOM" id="CLU_2382180_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1349-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="94" mass="10177" checksum="C5C36533BBE40C0B" modified="2008-01-15" version="1">MRHDDGTISLSPRKNEQFSNAKEIGCQSLFIPANLQSAGFQVIQFDWKVKGPTNWLATFLAAECDYSSQVGATTIALGNSTAQTGSLCFTFTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2F5</accession>
    <name>A9B2F5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1355"/>
    <dbReference type="EnsemblBacteria" id="ABX04000">
        <property type="protein sequence ID" value="ABX04000"/>
        <property type="gene ID" value="Haur_1355"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1355"/>
    <dbReference type="HOGENOM" id="CLU_975815_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1376-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="31234" checksum="116545E95D470846" modified="2008-01-15" version="1">MLASHNRQSIKSLIIFGSGLAYVLSIVMMEVLVGFALGDISDSLIMQALVGIGILGTFLSACLIPLALHYWLAPGTQFIVGILFWLIDVVVLAINATTSYQLIKQLELSSFFTMWQLAIPFIGPAITIIGWGLVYLADDGQKDRQSDRLLETSKRALMREAEYARVSAEHEFAMKQIAQVKQSLMMALQASDIAKVAEQGAYNSALTITRQIVGLPIDTTIPPSRSAELPPVPPALQPVVPPMPPPRSTELPPLPVSSVPNQQPMQNEDDHWTLLFEQQANHPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J6</accession>
    <name>A9B2J6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1396"/>
    <dbReference type="EnsemblBacteria" id="ABX04041">
        <property type="protein sequence ID" value="ABX04041"/>
        <property type="gene ID" value="Haur_1396"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1396"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160607_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1417-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14937" checksum="92CDB5FFDCA51D05" modified="2008-01-15" version="1">MTTGLIYLIKSEMDARGWNQTKLSEISGIPDSTISKILKNPNQIPKLENLATLAQAFDIPLARIIAACGFDVSSAKSEDSQRLQTIVSAIPDFQRLVEEMMTFSPLDQADVLAYIEMRRLHRQKNINQEVDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2K8</accession>
    <name>A9B2K8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2821</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2821"/>
    <dbReference type="EnsemblBacteria" id="ABX05459">
        <property type="protein sequence ID" value="ABX05459"/>
        <property type="gene ID" value="Haur_2821"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2821"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_6_1_0"/>
    <dbReference type="OMA" id="WLFQIAN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2852-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="101"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="21165" checksum="5BFF01ABA816C8A7" modified="2008-01-15" version="1">MNQLDLTNLWQNLAQPLRRFLQARLADQAAVEDLLQDIFLAAYLKSAQLQDSERSEAWLWQIARRKLIDHYRVRRETSPLDEMQAAENNQQPPILAGFDACVQQMLDRLPSQDRWVLQRTAFEGISQQALSSELGLSFSGTKSRVQRARQKLRVLFDQCCVVERDPAGHVLGCHPHRQLIQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M8</accession>
    <name>A9B2M8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2841"/>
    <dbReference type="EnsemblBacteria" id="ABX05479">
        <property type="protein sequence ID" value="ABX05479"/>
        <property type="gene ID" value="Haur_2841"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2841"/>
    <dbReference type="HOGENOM" id="CLU_2206406_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2872-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="12222" checksum="21AC4CBD14468B1F" modified="2008-01-15" version="1">MDGMSALVVIIGAVGLITLLIMRTKTYRERLRFQARAMDRHMRTTNIRDDVRQDILDLLIRGDRLAAIQYAHEQTHLDLLEARTLVDDIEKALKKHDQTQGASSDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Q3</accession>
    <name>A9B2Q3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMMECR1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2866"/>
    <dbReference type="EnsemblBacteria" id="ABX05504">
        <property type="protein sequence ID" value="ABX05504"/>
        <property type="gene ID" value="Haur_2866"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2866"/>
    <dbReference type="eggNOG" id="COG2078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095686_1_1_0"/>
    <dbReference type="OMA" id="WAIEVIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2897-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="20976" checksum="5C7B29877114E444" modified="2008-01-15" version="1">MPKQAALIVQDPLVVLARQAVNRFIRQGELLPVTEPLPSDQRRSQGVYVSLIKAGQLRGCVGSVQPQQASLAKEVIYMAVAAAVHDPRFRPVQLDELDQLSYIVDLVENLALLKNKAAHDPVAEGLRVQRGRNQGVVLPNTTGITTFEQQRQLAYQRAGLELTISATLERFQVRRIIELSGNYQETISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U2</accession>
    <name>A9B2U2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2905"/>
    <dbReference type="EnsemblBacteria" id="ABX05543">
        <property type="protein sequence ID" value="ABX05543"/>
        <property type="gene ID" value="Haur_2905"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2905"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775619_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2936-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731833" evidence="1">
        <location>
            <begin position="21"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="37852" checksum="7A9364308040892F" modified="2008-01-15" version="1">MKKQLLIVGLIVGLAGCGAASNSVTTVPQVLTAPDAANLAGYCVDTAPITKPVIVGLEGNMWSINGDGTEASQLTTVKERTLIRDAAWSHDRKTLAYSLMLPPIDLAIPWLQSSIVCGIDAATGKGSLLAYGNIDVSLSEPSWASDNQSLYLTRRRTLLDAKNQFVGEEIAVARYALGSNQETVVVEGATTPALSPDGQHLVYVQPNVEIGFPSLMLAKLDGSAAQPLGQPDLPFKSIVAPRWSPDGSSIVMTVGGGPGAIGGGAEPSLAWWEVLLGVEIASAHGEPVSLWQVNANDGALKPLAQNIDDGRTAWNPDGEHFLFIHGYDGLMEYTLATGEDRALTPVQPYWFLEWASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2W5</accession>
    <name>A9B2W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3392"/>
    <dbReference type="EnsemblBacteria" id="ABX06028">
        <property type="protein sequence ID" value="ABX06028"/>
        <property type="gene ID" value="Haur_3392"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3392"/>
    <dbReference type="HOGENOM" id="CLU_2409253_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3429-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10738" checksum="DF91579C045CFECF" modified="2008-01-15" version="1">MITERSINLFNSSSLETTLYGFAMLGWSLWVTSHIGYYWLFMRQYRATATEPRPTLALFEAWLNPSQQRVLIIFQASSVGFGVLWLLTKWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B309</accession>
    <name>A9B309_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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    <dbReference type="KEGG" id="hau:Haur_4842"/>
    <dbReference type="eggNOG" id="ENOG5033CEY">
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    <dbReference type="HOGENOM" id="CLU_1132377_0_0_0"/>
    <dbReference type="OMA" id="QMLATIR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4902-MON"/>
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            <begin position="1"/>
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            <begin position="27"/>
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    </feature>
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            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="245" mass="25575" checksum="0965B6A011ABD7F2" modified="2008-01-15" version="1">MKTIGKWLAIVAIAFALVFVGGRLTSTQAQTPTTPDTTETQPTTPDSTTANPGQGFGFGKRGGRGGGMGQRGGMGIHHQLVEQTAALTKLTTADVRSKLVEGASLTEIATANGSSEQAVIDAAVAQMETNLSEAVTNGKITEDQKAERLATAKTEAPTLMNQKGVVSEKGPGRGGRGQHLLVQATADVTGLTVEQVQAEVQAGKTLEQVAQANGKTVDDIIANLRTKGEERLNTELERAREALTK</sequence>
</entry>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ABX07476">
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    <dbReference type="KEGG" id="hau:Haur_4846"/>
    <dbReference type="HOGENOM" id="CLU_1842366_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4906-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="127"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15829" checksum="A43AF895488EFA58" modified="2008-01-15" version="1">MYRVPHNPQPKYRWPMILMCCYYGFVGFLAILGSCTFFSIMIDSKMLGGNYILSLLWSSVLLLANVSRLGLLVGLLKFYRWAYYGALIIELLTIINLISQFVLHSGLITWPELASGLIGMLILGYLLQPKIKQQFLKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B318</accession>
    <name>A9B318_HERA2</name>
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        <submittedName>
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    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
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    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4851"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
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        <location>
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            <end position="98"/>
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            <end position="347"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
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    </evidence>
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        <source>
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            <dbReference type="Pfam" id="PF03816"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX07481.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="47383" checksum="199A21A6693ECD81" modified="2008-01-15" version="1">MECQDVRRQLAAGIRPAVRPPERAQMGFHIANCADCYALLEVLQVEEQRQLLTTLLEEPVLAAPTPTPALTKPTRRRWPLAVFAMLAVLVLGGSWWWWSTPEQVVGVQIEPSNTPAPVIAGGIAEPSVIPVIQPTATAQAIATTEPSVTPRPTSTPRPSATPRPLAAMTVAILGLDRRPGETEPARADALLVLHLNPRNQSAALVSLPRDLWVALPPEYGFSVKLNAAYMYGEGDNGDAEAGAELARQTLSTTIGQPIDAVVVTTFEEMITMVDLIGGIDVDVPKEIYDSRYPTFDYGYMEAHFLPGMQHMDGATALIYSRTRHADNDFERGKRQQQVLLAIFARLQNLMQANNSVDNIELVSSLYNTLEYTSIDLPTTLRLVLAIQNFEPAGIQRESIDLNYGYETSTSDGAYIIQPDLPAIQSRIAELFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B343</accession>
    <name>A9B343_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4876"/>
    <dbReference type="EnsemblBacteria" id="ABX07506">
        <property type="protein sequence ID" value="ABX07506"/>
        <property type="gene ID" value="Haur_4876"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4876"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1150625_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4936-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="241" mass="26896" checksum="CE4CC1085D6DCA92" modified="2008-01-15" version="1">MSRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDRLVRDYILLAKGEYGVLSEEKVAQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLVLANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSVAVVFTVEGVPLTDEDLPRIFDRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3C6</accession>
    <name>A9B3C6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1445"/>
    <dbReference type="EnsemblBacteria" id="ABX04089">
        <property type="protein sequence ID" value="ABX04089"/>
        <property type="gene ID" value="Haur_1445"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1445"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_473096_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1467-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="342"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="576" mass="63732" checksum="1DABAF8E0A48827F" modified="2008-01-15" version="1">MNEFDSVVEAIEAGWELDDILQLIVTNSQVLLDLQHGYIVLYEAEQLWLKANTSNLPTRVLAPTSAEARVIAMGRAVALEPIQALPLWRTLEFALKPDARSWLSAPIRLNGHTVGALAAFAEPSDNEPLREALRFMTVLADLAALALERGQFWLRHQRRSQFIALLRTISGIIQQQSLGDLAHTIAQQLCEIGNADLALMYIPSPETEEFVTLGLSDTPLALQIRELGLDHIPLASNALLHECYQTGQAQRLALTNEQWPELAQLGVQQLLIVPIHDTHERLGVIVLASLQDTRFDDDALNFLNFIGVRLGYALKNENLLEEVVQAERRRINEDERSNFIASVAHDLKNALTTVIGTTQLGMRKLRRGDQSYSEKAFSTIATKSQQALQLIEDMVDVSRLEQGTFRLFIQSIDLVQLVADEAEAARGLSQRHTIQLSSSLEHYELAADQQRLRQVLANLLINAIRYSPDGGTISVRIMDADHAPAPSNASISSESELEQAVVISVSDQGIGIPEHELPYIFERFYRGQGSTVASGSGLGLYISAAIMAQHGGKMWVESKLNQGTTFYCSLPAARVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3N2</accession>
    <name>A9B3N2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2966</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2966"/>
    <dbReference type="EnsemblBacteria" id="ABX05604">
        <property type="protein sequence ID" value="ABX05604"/>
        <property type="gene ID" value="Haur_2966"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2966"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_0"/>
    <dbReference type="OMA" id="KPTNVMV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2998-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="569" mass="60181" checksum="9EAA302C8C4F85A3" modified="2008-01-15" version="1">MTSWNGRQFGKYVLHNEVGRGGMARVFRATDTTLQRTVALKILAPQLASDPESSQRFEREAITAGNLHHPNIVTIFDVGEAEGLPYIAMEYIAGRSLQAVIDEQGALGLGYAVALLMPVAEALDYAHSQRAVHRDVKPHNILLNADGRVLLTDFGIAQAPVVNDKRLTRAGMFMGTPEYIAPEQASAQLVDGRSDLYALGIVAFEVITGQVPFTGTVPELLVAHTYTPPPAITSLVPGLPAAFDKVFERALAKQPSDRPPSAVAFIDALRTLSGRAGIMIPSKDDLRGLAVPAGSSAGKATVAMNALPSLQRQHDPNAQTDVGSIQPQARPAAPVPQPVPRPSNPNPTARVAPSAQSRPQAAPAQPRPRPTPPSSSNAARPRMRTRPVMRTATTSDPLKIIYPVAIIITLAVLGIVFWQRIGQGNRGLISLPTATQTSSLSGPFVPESTRIPTAVPSNTPEPTPTDAPTEPPSITPEPSATVPSNTPTRTTQPTRTVPPTRTTQPTTVVPSNTPVEPTPIQATPTDVPPPTPTNGPTVAPTQDLPTVTNPGVEPTVVYPLPRPAPSPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3P0</accession>
    <name>A9B3P0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05612">
        <property type="protein sequence ID" value="ABX05612"/>
        <property type="gene ID" value="Haur_2974"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2974"/>
    <dbReference type="HOGENOM" id="CLU_1914169_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3006-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="14455" checksum="FACA993659469F5D" modified="2008-01-15" version="1">MAVFVEQEAILELLQTSRAASLAAMQYVQPADLAQLIALEQQATYDCAAHANQSPQLVDAANSLDQWQQQRQQLAQAIAAIPWAGYTQRIQTAAGALYLGELVKRLIAAEHQQLSQLLHAGQHPAIIDQWAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z9</accession>
    <name>A9B3Z9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3499"/>
    <dbReference type="EnsemblBacteria" id="ABX06135">
        <property type="protein sequence ID" value="ABX06135"/>
        <property type="gene ID" value="Haur_3499"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3499"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_0_0"/>
    <dbReference type="OMA" id="RAWWVVS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3536-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="120"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX06135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="35573" checksum="4F2BDA6AA8450164" modified="2008-01-15" version="1">MAVSTTQVEAHEPKKEEYERPWLEVLKRFTRHRFAVGSVVVLSLMILAVTFGPLFMPFGETDSAVTKKDQPPGTEYTLPKDLYYNSIGGEVRTPKGTTLTFWLGSDNIGRDLLTRLLYAGRVSLYIAVAVTLLSELIGIIVGVMSGYFGGLVDAFAMRFVDFLNTLPLLPILLIISTILEPTINLLILILVFFSWTGGARLMRGQILSLREQEYVSASRALGASNLRIMFRHLVPNALAPNIVNASLALSGVMITEAALSFLGFGVKLPAASWGNMLKGVNTTILEKYTWQAFFPGLAIFICSLCFNFIGDGLRDALDPRAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4A8</accession>
    <name>A9B4A8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysA</name>
        <name evidence="6" type="ordered locus">Haur_0013</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0013"/>
    <dbReference type="EnsemblBacteria" id="ABX02665">
        <property type="protein sequence ID" value="ABX02665"/>
        <property type="gene ID" value="Haur_0013"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0013"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_1_0"/>
    <dbReference type="OMA" id="YCRSMAS"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="61"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="310"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="302"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX02665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="47268" checksum="9FEE692798D9B6AD" modified="2008-01-15" version="1">MEHAEVRRMPNAHVWPISASVVHERLQIASCDLAALAAEYGTPLYLLDAETIRTIAMRYSAALRHAYGSNVSIHYASKALLNVGVARLVHSLGLGLDVVSGGELAIAQRAGMPLDHVHLHGNGTPPAELAQAVEAGIGRIVVDNLDQLKWLADYCAKRPTPQTILLRIAPDVTAGAHAHIRTGAASAKFGMPLDDGTAAEAVRLALQAPGLNLVGLHAHIGSQMRDWAALREMIGRLLAFADQQRRERSWLLTEFSPGGGLAVAYMPNEQAGDIETYANTIANAVRLGCERYQIPLPRLIIEPGRSLVARAGVALYSVTGHKTVVGGSDYLHIDGGMGDNLRPSLYNAQYTAALVARPCAPPIAPVQLAGRFCESGDVLIREVALPAAEVGELVAVPVAGAYTLSMASAYNGVPRPALVLLDRGQAMLIQRRETYADLMARDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4I8</accession>
    <name>A9B4I8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1509"/>
    <dbReference type="EnsemblBacteria" id="ABX04153">
        <property type="protein sequence ID" value="ABX04153"/>
        <property type="gene ID" value="Haur_1509"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1509"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_5_0"/>
    <dbReference type="OMA" id="IGIDMAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1531-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28367" checksum="5494DB21F4F2891C" modified="2008-01-15" version="1">MLVKSGYAPIHDLQLYYEIHGSGQPLVLLHGGLGGIGMFADLLPALAEQYQVIGVELQGHARTNDIPRPLSYAAMADDVAALIQYLGFSQVDVVGFSLGGGVALQTAIRHQQLVGKLIVISATFRDTAWYPAVRAAIGQLDEVAAAAMVESIPYKFYQEYAPNPANWVQLVCKTGAMGKQSFDWSSDVAKLQSPCLVVQGDADSIPLRHAIEFFELLGGPQSHDPEQRSQSQLAILPNINHFNIIDRIDLLMPVINQFLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4N0</accession>
    <name>A9B4N0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1552"/>
    <dbReference type="EnsemblBacteria" id="ABX04195">
        <property type="protein sequence ID" value="ABX04195"/>
        <property type="gene ID" value="Haur_1552"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1552"/>
    <dbReference type="eggNOG" id="COG0325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059988_1_0_0"/>
    <dbReference type="OMA" id="IEWHMIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1576-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="248" mass="27517" checksum="187410EAC19FAF71" modified="2008-01-15" version="1">MPFDHARLLEQVAQIQQRISQAAQRSHRDPASVRLIAVTKTHPMLRINAVLAAGIHDLGENRVQEAEEKIALQTPEALAQTRWHLIGHLQRNKARRAAKLFSLIHSIDSVKLAEILNRIVDEEASVIPQPLPILLQVNVSGERSKDGFELAGGVHNSAWLDFVGEVRAIAELPLIDLRGLMTIAPYSDDVEGVVRPCFRALREVRDQLEQRLDRPLSELSMGMSGDFEVAIEEGSTIVRVGTALFGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R9</accession>
    <name>A9B4R9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3004"/>
    <dbReference type="EnsemblBacteria" id="ABX05642">
        <property type="protein sequence ID" value="ABX05642"/>
        <property type="gene ID" value="Haur_3004"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3004"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3036-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="583" mass="60566" checksum="55AAF94F5B7DFB5C" modified="2008-01-15" version="1">MPNTKRYLITGGIGFAVGTFFLWNYPNLALGSAIIGGLVIAALCLLYSAPLPDMVKGGLIAGLFGAVMTIVYGPDKPGVAIIAGMLSGLGAGLLAFQRKPQATPQAGAALGAGAGAIAGAWTALALFLTAFVIAPAAGVDASEFAEHLSETVILADAMGLASDILILLFVLVFCTITGALLGAAAGAARALPLRPNIPLLAVIALPVILIPLIDRAGNLLLLDALIPIYIFILLALGLNIVVGYAGLLDLGYAAFFAIGAYTTAMLSSPHLGINISFWLVIWVAAAVAAIAGLALGAPTLPLRGDYLAIVTLGFGEIVPILFRNLGGGPPTGTLTLRFFGLPIGIEQMDLTGGNKGINPISPPNLPLIGNFEPSNKIPWYYLLIIIMGLAIFFINRLRDSRQGRAWMAMREDELAADAMGINVVRTKLLAFSMGAMFSGFGGAFYGAFIGAIFPSSFDFSVSIILLCMVILGGLGNMAGVIVGGLLIQGADKMFIPKGAELFRDIADQRALTTGGSTVGVSALQDLTQQRLLLFGIVLVVMMLIRPEGLLPNERRKAELHSDDDPININSVAAEADADPSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W5</accession>
    <name>A9B4W5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Basic membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3050"/>
    <dbReference type="EnsemblBacteria" id="ABX05688">
        <property type="protein sequence ID" value="ABX05688"/>
        <property type="gene ID" value="Haur_3050"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3050"/>
    <dbReference type="eggNOG" id="COG1744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038813_0_0_0"/>
    <dbReference type="OMA" id="QYANSFT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3082-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732464" evidence="3">
        <location>
            <begin position="21"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="4">
        <location>
            <begin position="85"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="39576" checksum="0B8C7432CABEEFC7" modified="2008-01-15" version="1">MNKRMIAFMMLLVLMIPVLAACGTETAATTAPAATATTAAAAPTATAAAEVTASPATEATAVATAAATAEATTGASTPSDIKIGLVTDVGKVDDGTFNQFAFEGLKRAETELGVKIDYIETIDPKDYEKNIEQFASQGYDLIIGVGFLMGDAIKAAASKYPDLKFAIVDFAYEPALPNVKGLVFSEDESAFIAGALAAMVSKSGKIGAVGGKEQVPAVKKFVLGYEAGAKYVNADIQVSKVYIDSFTDPTAGGEAAKTQIAEGADVIFGAGGQTGSGAIKTAADNNVFVIGVDQDEYNTTFKKGPAPMLITSAMKRVDNAVFDVVKEVVDGTFAGGLYLGNAANGGIDYAPFHDAESALPADAKAKLDEIKKGLADGTITTGVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Y5</accession>
    <name>A9B4Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ABX05708">
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        <property type="gene ID" value="Haur_3070"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="AQFLNFA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3102-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    </dbReference>
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    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="172"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="38"/>
            <end position="319"/>
        </location>
    </feature>
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        <location>
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            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="385"/>
            <end position="392"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="604" mass="67097" checksum="9BFC38D8BD891BC7" modified="2008-01-15" version="1">MGFIMDGLDAEAYDRTYTDGQLLRRIMHYFSPQRRAMAIAAGAIFLNAVLDTALPIFVSISIDQLQVDRSLSTFIYLAVGLSLIATLAWVFNAVRQQLSSRAVGDVVLALREDACDAVLERDMSFYDTFQSGKVVSRVNSDTQAFSQVMTLTLDLLSRLLLVSLLIGYLFTIDVKLTFTLLGFAPIIFLFALGFRKIARRTITQSRRMTATVSSHIQETVSGIGVAKTFRQEPVIYREFHEVNEKSRSVNQKTRFVFSSIFPLMNGLAGIGTALLVYWGAVSVNNESLSIGDWFLFVQGLTMFWFPLTSIASFWSQFQLGLAAGERVFALIDAESNVVQNNNRKLTPVRGRINFKQVNFSYTPDEPVLRNFSLEIQPGETIALVGHTGSGKSSIAKLIARFYEFQHGTIEIDGVDIRELDLGDYRSQLGIVTQTPFLFDGNVRENIRYGKPDASDEEVQTVARLVGGGDWLGSLPNGLDTDVGERGGNLSLGQRQLVALARVLLQNPAIVILDEATASIDPLTEALIQEGLDVILKDRTAIVIAHRLSTVRHADRIIVLRKGEIIETGSHEGLLDQAGHYAELYNTYFRHQSLEYIESGVKNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B548</accession>
    <name>A9B548_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX06185">
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        <property type="gene ID" value="Haur_3549"/>
    </dbReference>
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    <dbReference type="OMA" id="VWAVGKT"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
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        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="HEM4" evidence="1">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="29328" checksum="A1A2F7707A4480A1" modified="2008-01-15" version="1">MTMHTPLTGKRIVLTRAREQMTEFAQLLADHGAETLYCSAIQTLPPDDWQPFDRALSQIEGFDWMIATSTNAVRAFFERYGVLGLPCNALNQLKIAAIGKATAKLLTDFGHAPDFVPHAYVAEQFLVEFQDIAGQRIFLPQADIARPLLREALIERGADVTAVVAYRTVPDPQVVALAELLRQQRVDVVTFTSSSTVRYTIEALHAAGMRNSQEFLNQTIIATIGPITSQTALDVGLHVDIEAAEHSTQGLVEALLEWAKTEKELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B552</accession>
    <name>A9B552_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3553"/>
    <dbReference type="EnsemblBacteria" id="ABX06189">
        <property type="protein sequence ID" value="ABX06189"/>
        <property type="gene ID" value="Haur_3553"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3553"/>
    <dbReference type="HOGENOM" id="CLU_1501531_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3590-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="179" mass="20648" checksum="47BFDED8155984D2" modified="2008-01-15" version="1">MTVYKSAATKYAVPFVVILVVATVILVSKNEFFDAAISFGLSTIPIGFTWLSHKWRFITADDYMHIDSLVLGKKINWNEVIAAEDMTYDNGMYLLRVINKDQMFEIPVTMLKGKDIVTIVNYVNQKNKQYEIPFNHGIPYFKSMYYQYKPNILSNIGYFAPALHDKTKVWNMVYGLSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B599</accession>
    <name>A9B599_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3600"/>
    <dbReference type="EnsemblBacteria" id="ABX06236">
        <property type="protein sequence ID" value="ABX06236"/>
        <property type="gene ID" value="Haur_3600"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3600"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_4_2_0"/>
    <dbReference type="OMA" id="LPAHIQY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3639-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="212" mass="22782" checksum="B0CC448D7BEB6270" modified="2008-01-15" version="1">MAPPVVLPDLQTLTVDAAAALAYLLAGNARFVANLPLEPHHDSLYRQQLTQGQHPFAMILGCVDSRVIPELLFDCGFGDLLVIRTAGHAIDEVTVGSIEFGADVLEIPLLVVLGHEHCGAVKATINMLDQHQTAPDRIAVLVDHLRPAVAEIDIHAPDRLDAAVRANVVHTVAELQRIPLLAQREQAGLLRIVGAYYSLVSGAVELLTTPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B0</accession>
    <name>A9B5B0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methicillin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0083"/>
    <dbReference type="EnsemblBacteria" id="ABX02735">
        <property type="protein sequence ID" value="ABX02735"/>
        <property type="gene ID" value="Haur_0083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0083"/>
    <dbReference type="eggNOG" id="COG2348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048411_0_1_0"/>
    <dbReference type="OMA" id="WEIFTAT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-84-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02388">
        <property type="entry name" value="FemAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="39925" checksum="A61B54253E9BCFCC" modified="2008-01-15" version="1">MSFALRELDAAQWSAELAANPAVHLLQRAEWGQLKAQFGWQPQRIAIYNQHGFCAGAQVLWRSQYGLRVAYVPRGPVWSADQAANRLLLQSLERLARKRWAAFLRLEPNLLDAGAADQLHSELLLAGYEQSRSMQPSASIHLDLQPELASLQAQCSKGHRADVRRAERQGVSIRVGTTEADLDQFYAIMQATSQRANFGIHSREYYAQAWRLFGGDQADGAARLLIAEREGRVIGSFLVFAQGTEAQYMYSGTNEEGLKFAASHALQWAAITWAKQRGCTLYDFWGIPEAFLALEATTDPAERERLDQAAQATGMAGVYRFKKGWGGQPVRYLPAYDRVFLRPAYWLWQRRRSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5I5</accession>
    <name>HIS6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="1">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ImGP synthase subunit HisF</fullName>
            <shortName evidence="1">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisF</name>
        <name type="ordered locus">Haur_0158</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5I5"/>
    <dbReference type="SMR" id="A9B5I5"/>
    <dbReference type="STRING" id="316274.Haur_0158"/>
    <dbReference type="EnsemblBacteria" id="ABX02810">
        <property type="protein sequence ID" value="ABX02810"/>
        <property type="gene ID" value="Haur_0158"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0158"/>
    <dbReference type="eggNOG" id="COG0107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_4_0_0"/>
    <dbReference type="OMA" id="IFHYKET"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135008" description="Imidazole glycerol phosphate synthase subunit HisF">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <sequence length="263" mass="28341" checksum="56D58C89A1F9D129" modified="2008-01-15" version="1">MLTRRIIPCLDVKAGRVVKGISFLNHRDAGDPVQLAAFYNESGADELVFYDITASSDERNIMVEVVENVARQVFIPLTVGGGIRTVDDMYRMLRAGADKVSINTAAVLNPQLIEDGAKRFGSQCIVLSMDARRINEPGQPSQWNVFTHTGRDPRPTGLDAIEWAKRVVDLGAGELVINSMDADGTGAGYDNELLSAISQQVGVPVIASGGAGKPEHLLAALHEGKADAVLAASIFHFGTYTVEAVKEYLANQGIPMRRTPRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B613</accession>
    <name>A9B613_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3169"/>
    <dbReference type="EnsemblBacteria" id="ABX05806">
        <property type="protein sequence ID" value="ABX05806"/>
        <property type="gene ID" value="Haur_3169"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3169"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1102167_0_0_0"/>
    <dbReference type="OMA" id="HDYLYTY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3201-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039248">
        <property type="entry name" value="Ptase_RsbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35801">
        <property type="entry name" value="PTHR35801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="26224" checksum="53A576A5A0C20231" modified="2008-01-15" version="1">MLELQVGVAKVGKYATPESGDTLEMIERPHGGFSFVLADGQGSGRGAKTLSNLVTTRAISMLKDGARDGAVARAVHDYLYAYRHGQVSATLNILSVDLSARSVLVSRNNPCPFYVIDEQGMTTYNEPSTPIGLYSMTKPVITKISLRPYVYVVVFTDGILHAGRRYNESIELDNYLGNFNVRQGRTAQEVTDDLLGRAVELDQNRPNDDMSVIVMAALPMESENKVRRMTVCFPVERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B640</accession>
    <name>A9B640_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3615"/>
    <dbReference type="EnsemblBacteria" id="ABX06251">
        <property type="protein sequence ID" value="ABX06251"/>
        <property type="gene ID" value="Haur_3615"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3615"/>
    <dbReference type="eggNOG" id="COG4101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090057_0_0_0"/>
    <dbReference type="OMA" id="HTWYGDR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3654-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017102">
        <property type="entry name" value="UCP037087"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037087">
        <property type="entry name" value="UCP037087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="136" mass="15028" checksum="73DB723208297378" modified="2008-01-15" version="1">MTDQASCVIIRPNEQTGFAGKQGLDYFSGIAAETAGSQAICMHMLRMPAGARAKAHHHENHETAIYMLSGTVEMYYGQQLEHHAVVNAGEYVYIPAGMPHFPFNPYTEEAVAIIARTDPHEQESVVLRPDLERLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B699</accession>
    <name>A9B699_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3674"/>
    <dbReference type="EnsemblBacteria" id="ABX06310">
        <property type="protein sequence ID" value="ABX06310"/>
        <property type="gene ID" value="Haur_3674"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3674"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_0_1_0"/>
    <dbReference type="OMA" id="YYDAARH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3713-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="27558" checksum="0B38EE133CE348F4" modified="2008-01-15" version="1">MPRWALLADVHGNRLALAAVLADLAQRHVDQIINLGDSVYSVLQPRWCAEQLAQIANISISGNQDRILFEQIPVEQQTLSYRFVQADLGPNERNWLTNQPATAIVDDIFCCHGTPSSDTTYLLEHVTPHGVLLHSEETIRAAIQGISQSLIVCGHSHIARTVQLSNGQLIVNPGSVGIPAYNDDQPYPHIIEAGSPHARYAIVERNAQSWQVEHFTLGYAWQQAAATAQHNGRDNLARWLQTGRAKLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6H7</accession>
    <name>A9B6H7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0228"/>
    <dbReference type="EnsemblBacteria" id="ABX02880">
        <property type="protein sequence ID" value="ABX02880"/>
        <property type="gene ID" value="Haur_0228"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0228"/>
    <dbReference type="HOGENOM" id="CLU_753926_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-231-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734589" evidence="2">
        <location>
            <begin position="23"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="367" mass="42654" checksum="E1D79ED66DCA142D" modified="2008-01-15" version="1">MLRRLLLAGMVLLLVGCQEPLAQLDCFRPLINTPTTQLPTGQRLVMIDRILAIEPAPTKPITLQFALVNNPSTQFSFNFNQKNNHVKFVDLENFFGIKPIATLECQDSFAPQHYSFVLEVIASTKTYTQPFDVEYKADINDFNYYGFQFTQSIDGILMTVTIIGIGLIFLSIMYGVILVILFRNKLYTKKLVVAILLSKLFLIIVIFHIDFYNFNQKPPLYCYSMIIVANETYQPLGEGIKMFPNAIQSQTTDLEFYPMYTDLYNDSERYIYNNDIYRYRFYLKHMPALHSVPTYPNCEREFDFTYIDMYKFKQNNEVSTIPIIIKPFYKDQLDNNADFILAYDFAGAILTLSILAIPMLLFIRSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L3</accession>
    <name>A9B6L3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polynucleotide adenylyltransferase/metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_0264</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0264"/>
    <dbReference type="EnsemblBacteria" id="ABX02916">
        <property type="protein sequence ID" value="ABX02916"/>
        <property type="gene ID" value="Haur_0264"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0264"/>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015961_6_2_0"/>
    <dbReference type="OMA" id="GWTFHGH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-267-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="4">
        <location>
            <begin position="33"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="6">
        <location>
            <begin position="175"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="5">
        <location>
            <begin position="312"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX02916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="517" mass="57528" checksum="7183430D28172967" modified="2008-01-15" version="1">MKISHIQLPQSSAYLSLRQALSVLKHLLGSQPAWVVGGTLRDLVIGRPLHDVDLVVNQPAIGLAQSLAKQLNASLVVLDAERDIGRVVLADGKYLDLAHLRAADLTSDLTDRDFTINAMAAPLYEQAQLGQIIDPHAGLNDIATGTLRMVQANALANDPLRMLRAVRIAAQLGWQLDPATDQAIIAHAELINQVAVERVRVELLAILATRWSASWLRYLDRVNLLPSLIPEIRPMYHHTQPNIHFLDVWEHSLETITAGEWLLAQLEHDQQPVPPAPPALADDWHPPAFFQQPATLRMLPNLTLQLQWAEQVVAQMQQPIGHTASNRALWKMAILLHDCAKPATRVDKPDGSVSFHEHQTIGADIARAVYQRLRFSNQEIEYMCKVIAGHMRPGQLYSQPETTAKAAYRFFRDLKESAVDTLLHALADHMATRGPLLQEHHWAYQAAWTDAMLGFYWDAEAEQKRVPLLDGHTLMQELGLAAGPQIGLLLEAIREAQAAGEVTDRESALALARRLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R8</accession>
    <name>A9B6R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate dehydrogenase (Or fumarate reductase) cytochrome b subunit, b558 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1734"/>
    <dbReference type="EnsemblBacteria" id="ABX04377">
        <property type="protein sequence ID" value="ABX04377"/>
        <property type="gene ID" value="Haur_1734"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1734"/>
    <dbReference type="eggNOG" id="ENOG502Z7RU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077968_1_0_0"/>
    <dbReference type="OMA" id="LHFYDFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1761-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011138">
        <property type="entry name" value="Cytochrome_b-558"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02046">
        <property type="entry name" value="sdhC_b558_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX04377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="24676" checksum="3406D826C8938BA9" modified="2008-01-15" version="1">MTGVLSFYRTSIGKKVVMAVTGLIGVGFVIGHMLGNLQIYLGAEALNKYAAFLKSTGELLVVVRVVLLTAVILHIIAAVQLTIENRKSRPQRYVKKQHVESTFASRTMRYGGIILLLFIVYHILHFTIGKAPGGPQPFDVHNVYNNVVYGFQNIWVSLFYIVAMLSLGLHMAHGVWSLFQTLGLNNRRFNRLLRNAALGIGTLLFLGNISIPIAVLVGFLKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S2</accession>
    <name>A9B6S2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1738"/>
    <dbReference type="EnsemblBacteria" id="ABX04381">
        <property type="protein sequence ID" value="ABX04381"/>
        <property type="gene ID" value="Haur_1738"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1738"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_10_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1765-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732538" evidence="1">
        <location>
            <begin position="33"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="91"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="38306" checksum="6E8096A851391A9D" modified="2008-01-15" version="1">MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEATATAASDTTTTSGNRTFTHALGEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYPKWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSLRGETIYDQLNAIAPTMMFNPYLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLVAQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHMLYITEEDNDPFQSAAIKPYWDSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLSESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7M9</accession>
    <name>A9B7M9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0351"/>
    <dbReference type="EnsemblBacteria" id="ABX03002">
        <property type="protein sequence ID" value="ABX03002"/>
        <property type="gene ID" value="Haur_0351"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0351"/>
    <dbReference type="eggNOG" id="COG1125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_5_0"/>
    <dbReference type="OMA" id="DKICIMN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-354-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="35891" checksum="88166F2F44F7501F" modified="2008-01-15" version="1">MSTIEFRNVRKIYPKAATAALADISLTINRGEFVILLGPSGCGKTTLMKMINRLIEPSSGTILLDGVDIQSINATKLRQQIGYVIQQVGLFPHMTVAENIAVVPKLLGWPKAKIQSRIDELLQLIQLDPAQFRQRYPAQISGGQAQRVGLARALAADPGVMLMDEPFGAIDAITRTALQDEMLRIQQQLQKTIVFVTHDVEEALRLADKIAILHEGTIVQYDTPLNLLRNPANHYVAELLGADDLVRRLSLIQVRHVLQPLPASYDSSLASIESSRNLRDGLNQLLASSDEQLLVVEHNQPIGMLSLAAIHAYLHPEVIHERHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7P3</accession>
    <name>A9B7P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1778"/>
    <dbReference type="EnsemblBacteria" id="ABX04421">
        <property type="protein sequence ID" value="ABX04421"/>
        <property type="gene ID" value="Haur_1778"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1778"/>
    <dbReference type="eggNOG" id="COG4228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118455_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1806-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="191" mass="20638" checksum="3389BED9046841F3" modified="2008-01-15" version="1">MALELAGIALQRVHRIQTLEQRAAVYHHVPGMAGDVSQQLGRHSVCLQIEGICYGAEAQTMLEQLRGIYLKQEPVEFIADIVGQGYVAKVTLDQFQVTQQAYEPDQYSYRLQIVEYAASSKSKVAAAQVNASIKTQAVQLTTLASLPDALAFGSLPEITNPVEPLKTALDPVREAASSLSDSLGALRSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U0</accession>
    <name>A9B7U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1825"/>
    <dbReference type="EnsemblBacteria" id="ABX04468">
        <property type="protein sequence ID" value="ABX04468"/>
        <property type="gene ID" value="Haur_1825"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1825"/>
    <dbReference type="HOGENOM" id="CLU_3008107_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1853-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025844">
        <property type="entry name" value="Herpeto_peptide"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14409">
        <property type="entry name" value="Herpeto_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="52" mass="5712" checksum="A35AE8DCAA6339E7" modified="2008-01-15" version="1">MEFENIKTEELPVIFGLTYLEEEAAEIDDVVGCLMPIDGYSGTSCDDIDAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B849</accession>
    <name>A9B849_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyhypusine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3346</name>
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    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3346"/>
    <dbReference type="EnsemblBacteria" id="ABX05982">
        <property type="protein sequence ID" value="ABX05982"/>
        <property type="gene ID" value="Haur_3346"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3346"/>
    <dbReference type="eggNOG" id="COG1899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057081_0_0_0"/>
    <dbReference type="OMA" id="FWSYFCQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3383-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="36745" checksum="43CEA53FB826CCF6" modified="2008-01-15" version="1">MSTTPISDFLRHNFRHFNAAAMIDASDAYVRHLENNGKMMITLAGAMSTAELGISLAEMIRQDKVQIISCTGANLEEDLFNLVAHDYYERVPHYRDLTPDDEAALLVRHMNRVTDTCIPEEEAMRRLERALVDEWTAADAAGERYFPHEFLYRILRKGVLEEYFQIDIKDSWMYAAMEKNLPIIVPGWEDSTTGNMYAAHCIQGEIKNIHTVRTGIEYMAYLAEWYIEISKTHSIGFYQIGGGIAGDFPICVVPMLHQDMQMGNVPVWGYFCQISDSTTSYGSYSGAVPNEKITWGKLEPTTPKFIVESDASIVAPLMFALILGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8D9</accession>
    <name>A9B8D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhs element Vgr protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3858"/>
    <dbReference type="EnsemblBacteria" id="ABX06492">
        <property type="protein sequence ID" value="ABX06492"/>
        <property type="gene ID" value="Haur_3858"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3858"/>
    <dbReference type="eggNOG" id="COG3468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1076766_0_0_0"/>
    <dbReference type="OMA" id="CPYNTVP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3900-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732619" evidence="2">
        <location>
            <begin position="33"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="27782" checksum="EA43E6FBEDD7394A" modified="2008-01-15" version="1">MFKFRSISSKRLTLFASSLGLLLIAGCSQTTQQTQNSSNYPGPQATATALIASTTRTPRPEPTKTKTATAVATPTRPATYPQPTKTLVAVATRTPRPEPTNIASPVPATPSQTLVATRTPRPEPTLTPRPAPTATNIPPVNPYPQPTTGSQPTLVIQPTAGVQPTTGTQPEPTQTPRSEPTANPYPQPQPTRTPRPEPTANPYPQPQPTRTPRPEPTANPYPQPQPTRTPRPEPTANPYPQPQPTRTPRPEPTQHPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E1</accession>
    <name>A9B8E1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3860"/>
    <dbReference type="EnsemblBacteria" id="ABX06494">
        <property type="protein sequence ID" value="ABX06494"/>
        <property type="gene ID" value="Haur_3860"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3860"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1314698_0_0_0"/>
    <dbReference type="OMA" id="EDEQWES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3902-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="205" mass="23370" checksum="125BAC14EC63ADCF" modified="2008-01-15" version="1">MGTCMNTLANAALIPLLIAAKQADRGAFVQIYEHYRNALLRFFYAHCSSADLAEELSSELWLRVVEHLPHFNLPLEHADLAFTGWLFQIARHLLTDGYRQRQRQAYEPLNEATALANSDPTAISELHAIQASLVHALAALTPDQREVVYLRFFAHYTSAQVAAYTGRTEYAVKSLQYRALHTLARSTELRQWYLGEKEPLFKFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8E2</accession>
    <name>A9B8E2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3861"/>
    <dbReference type="EnsemblBacteria" id="ABX06495">
        <property type="protein sequence ID" value="ABX06495"/>
        <property type="gene ID" value="Haur_3861"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3861"/>
    <dbReference type="eggNOG" id="ENOG5032TYH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_794037_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3903-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732004" evidence="1">
        <location>
            <begin position="25"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="39492" checksum="A13C352778D211FF" modified="2008-01-15" version="1">MNRSSSLFTLLIVAILLIPTSSQATTSTSTRRFIDQPWLNLYYTNLVWEDTGKCRAMFRVKTTDLCTHGPDSPEPQMAKSWAEELFYPNNQMHLSIEQSSQPCLDDSTNDYRTQVLYVRASDAQDNSSIIAPVLRKHLLGVNEIYNQSAQLTGGQRHIRWQLNQACQIDVQHVVIPPAADDDFGATINAVVAQGFNRDDRKYVMFVEARYYCGIATVQHDTQPSSANLNNHSVAYARIDAGCWNARVVAHEHMHMIGGVQPSAPHTTKSWHCTDEWDIMCYSDAPSYPDLEIACPEHSIRDIFDCGNDDYFHTNPAADNYLASNWNSANSLFLSQQSQYWRIYLPIASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H5</accession>
    <name>A9B8H5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07639">
        <property type="protein sequence ID" value="ABX07639"/>
        <property type="gene ID" value="Haur_5009"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5009"/>
    <dbReference type="HOGENOM" id="CLU_699754_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5072-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="394" mass="42910" checksum="AC6F05F62B7D9C50" modified="2008-01-15" version="1">MTLLERKRATVYDHVRVNQPLRDLHYQLPAWITIADQPYLAVGDDNGNGAKKIAVLDAKSRLITTRTPTAYKLAKAIRAGQGVITYRVNGGDSFWIGDDALRFDGDALPIGGTSQRLSDTRQRSFNAACMVETLIKARYKPGVYPLAVGFAIPNEEIESRDNDKMGVNPETRTALKTHLNGQTFVVERTDALGVVTNWTLRYEKIIPQAQSIGTLYAWSRTVDGSLEADGIRRVSIVDIGGGDTQLTEVELNPYRMSAERLGAGTISIARELAAKFHRLRLSDAQAQYALETQLLEESGREFPIESEVNAAIQSAGQDLVGRMLKVLQQPSAYVIITGGGVKLQGLRRLIEERAEASGKTAPRNYTIIDPSVADILNATGALLAVVYAAAGKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8N9</accession>
    <name>A9B8N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein, DeoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07703">
        <property type="protein sequence ID" value="ABX07703"/>
        <property type="gene ID" value="Haur_5075"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5075"/>
    <dbReference type="HOGENOM" id="CLU_041141_4_0_0"/>
    <dbReference type="OMA" id="WVLLARC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5137-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="145"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="331" mass="38397" checksum="A72A935D2376793C" modified="2008-01-15" version="1">MSDDRLRARAARLYGIGRYLYERGTQGARVVDLAQYFDVHRSRIYHDLQFMQQEGEPIYQDGTRWYLERDRYIHRLPINLREALAFYLAARLLSKQSDKHNPYVVSALDKLGSALANNHRNIGLHIQRAANVVRQRPSDQAFTKIFETFARAWADQCRVEVTYLSAKSKYSTWEQRTISPYYLEVSGIGYSTYVIGHDNKSNAIRTFKLERIAAANLRPFDTFEIPETFDPQERLGNAWGIIWPAEGEEPVDVRLLFAPAVAHRVKETIWHPSQIIEDLPNGGCRYCVRVGSTLEMRPWVRGWGRDVAVEWPLAFRQEMIDELQAALALYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q7</accession>
    <name>A9B8Q7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07721">
        <property type="protein sequence ID" value="ABX07721"/>
        <property type="gene ID" value="Haur_5093"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5093"/>
    <dbReference type="HOGENOM" id="CLU_711282_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5155-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="388" mass="42874" checksum="D2F0779ECEA382A1" modified="2008-01-15" version="1">MKRIVLIAAGFEKHCLRLQPWRYLCEVAAQLQQHGHAVTIISTGTDPASLLYGIPIIRLSSIAAHPRNHALQAALHACQPDVVLWHLGKTSMLHGHYHYPGALNIGIFTSPLYHLAQLRTIGMGRLLKNYELGAMHLVGALIPQRIFQHGYQRQQLDHVVVQTQTTKAQLIDLGIAAHDITVLAPGVDSDWLTKPTHETDGRTALGFHATDHVLVYFGSPAPLRGLHTLLHAFSAARRQHPSLRLLILSRRHPRELQRADAQLGRLFQQSEIAPYVRIVSGYLPSQELVRHVALGDSVVLPFDLVPSDAPLSLLEAHALGKPLITTDISCLPEFAAYGPHVLAEAANPPSLQQALLASSQHRYRPPTTPSLVQSWTEMGTQWHHLLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8R7</accession>
    <name>A9B8R7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07731">
        <property type="protein sequence ID" value="ABX07731"/>
        <property type="gene ID" value="Haur_5103"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5103"/>
    <dbReference type="HOGENOM" id="CLU_663543_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5165-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="44473" checksum="90CEAF8F7D20EBB0" modified="2008-01-15" version="1">MSHPSTPPTVIATLDIAKHTHWFAVFAPDLTPIIPPHPITTDATALQSVITTLAQLALAGPVALAMEPTSIYHLPWLHALTAALPPTVTCLLVHTTAVHHARTRLTAGRLRKTDARDCHAIAAAVRDGHGRPWSPPSPQQAQFRTWAAQEAATMETLTQLAHALQRLTDLLWPGLVARRNAASTPLVSSRLWTRHIIQTILLHHPDPHTWRSLSVAAIRARLKALGMRCGIGRATHLAAILAAQVVLPPEQTPPLAARLTTLMQQYCHHATHLAALHAEAETLVAASWAAVLCSIPGMSPVLAARYAAAVGDIHTITSAKALWSLAGLEPSIYASGVRSRVGQSSLAGRITLRQALIRIGASLSRHCPPVRACWLAARARRKPLAVALIHAANKANRLLFALAISQQPYQPGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z8</accession>
    <name>A9B8Z8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_5185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="8 9">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="9">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8 9">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07812">
        <property type="protein sequence ID" value="ABX07812"/>
        <property type="gene ID" value="Haur_5185"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5185"/>
    <dbReference type="HOGENOM" id="CLU_011263_15_6_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5247-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07484">
        <property type="entry name" value="Peptidases_S8_Thermitase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034084">
        <property type="entry name" value="Thermitase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="156"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="605" mass="64219" checksum="23FB72303FD60BD0" modified="2008-01-15" version="1">MNIRFLGALGLLMIVLALPRNSVAEHQRSSASHDSAITISTTAPAVPGQFIVQFRPTASRNQRQSTLAVLGAYVVRRIEPLNLDVLEIPALTKTSTSTAMDRILAHARDNHDIVFLEPNYIYTTTYLPNDSAYQNQWAWSMVRAPQAWDITRGSPNVTIAVLDTGIDREHPDLKAKVVSHGIDLVTADGIAHDENGHGTHVAGTAAAATNNALGGAGMCPLCQVLPVRVLNAFGSGTLDAVAEGIIYAADAGVQVINLSLGGPGSFALQHAVDYAWTHGSFLACAAGNNGTASLDMAYPAAYGNCFAVAATTSMDQTADFSNYGSWVEMGAPGVNIYSGWLYGGYHTISGTSMAAPHVAGVAGLLASFGLSNSQIRSRLCTSADRTAATGSAYTCGRLNAWRAVSAAIPTTTPTLRPTTTRTPTPSAIPQPGVTVMPSTPPAHAPTVTAVPTVAVPGNTLINSGFEDGNAPWEQVSAWNYALIIDGPAHTGRRGALLSGFINGGDALFQTVTVPAHGKLTYYLRVTSDDAPTQPRDYLRVKLYTTNGIPIATLRTWSNATLWNIWIVDSVDMNAYAHQTLRIQFETITDSQWNTWFAIDDISLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B916</accession>
    <name>A9B916_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07830">
        <property type="protein sequence ID" value="ABX07830"/>
        <property type="gene ID" value="Haur_5203"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5203"/>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_0"/>
    <dbReference type="OMA" id="NRPVVGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5265-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="289" mass="30948" checksum="F2020E471571E263" modified="2008-01-15" version="1">MSSSPASRIMLVTGANSGLGRATALGLACDGATVIMICRDAALGAAAQAAIIRESGNPAVDLIIADLSSQHAIRQLAQTVLARYPQLHGLINNVGASFPTRRVTVDGIESSLAINHLAAFLLTNLLCDRLIASAPARIINVGTRITTRMDFDDLQFEKRPYRALAAYSQTKLGTIHFTYELARRLAGTGVTVNCVHPGVFKSRLGQDDGRQSWFFRMLGLLGQYVLPDAAQAAKQIVYLATSPAVADITGSYFAAMRPISSPPQTYDRAANARLWDLSATLTKLDTEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B930</accession>
    <name>A9B930_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07844">
        <property type="protein sequence ID" value="ABX07844"/>
        <property type="gene ID" value="Haur_5217"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5217"/>
    <dbReference type="HOGENOM" id="CLU_002836_0_0_0"/>
    <dbReference type="OMA" id="CQCKKNQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5279-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1525" mass="177021" checksum="CE25E5BAE00D56E0" modified="2008-01-15" version="1">MPELGGPTTQSGVFYQNSISALYLGRLCDGVVRPQNELVVEVRVEAPDSVDDTIITFEDQHRLYIQAKEHIQKGTKPWNKLWKDFSKQFQKSQFQPSRDRLVLYTGETRELIHNLREICERSYESQDYNEWWGRLSQAQQGLLKDIIPLVSAVDDDDDKKFILSLFRHIDVEVFTLRQIERDLVALWMPASNESYQTVFRLLRDHVGEKGRQRGIFTLKILKLILLDHEIIINTPSIEITRTSIQRCNALLMQCRNTVASTGVFIKRVVVDKIVDWIKNTPDSDNVAVLLDQAGMGKTVVMRSVLSTLQHQDIITLAIKADQHLSGIVEYPELQTMLAFSEPVEAMIRRLAITGKVVVLIDQIDALSLSLAHDQRSLDVVLQLIAYLRNIPNVRIVLSCRTFDYHNDPRFRQTHIAHHFVLEELESTDVAVVLKKLDIEFAFLAEVAKKLLKTPLHLDLFCLAMEQQATPPNYQRMLPSLTNLQDLYGLLWQNVILRAGMTVPSATDREDVLRLMTEQMHKHQRVTVAQSFFMSRDTMHLEKAVNWLGSAGILVQGNASWSFLHQTFFDYCYAKQFVESNNSLTQMIISSDQGLFVRPQLIQILTFLRGSNHRLYIQEIHALFHLQSLRFHIKDLLFRWFGACIVPTNDEWSLAQRMLIDPLHRGRFLMAIYGNLGWFERMRGIKIQALLKYDDQILDSEVIPYLDSLTEVAQTDIMQILQPYIGRSNEWNNRLGWVLSHIRHWQTLHAAEALENLIRITDIESFKNSYDLDDVTKAYPRVGCRILRIILDKVLDSYLIECEKHAKKQNYDTKWFISLPNLSRSLEALNSGMLMESLQNASKLEPSIFLEELLPWIEKVCEISNQSDNTDNKYPDDILSHDWYDTTYPVYHTLIHSIITSLTILAKTESNIFHVYADRLASKPFRTTQQLLIYVYRDVADQYTEDAFKFLLGDNRRLMLGDADIYDSRQLINTIYPFLSHQQRNDLEQYILLFNPHWNWKVYGLDALRWWRQEQMFLLQSIPVQYLSDKGLARLQELERKFPNYRVSSDPQRGGGFTIPSPIPKTKAQALSNKAWLRIMKEDQTNNWYKRSSHRGGIGELAHVLTEMIKQEPDRFYQLASQALDFIHPIFAQAFIRGFSELHTHPDRFFKLVRLFGNKLNLEGKRTVTWLLEERINEGIPDDVISMLKSWIYTSANSDEQNWENNDDLYSGSINTVRGCALRVVMQALRKQEDQITLQHQWQVIDVIAADPSRVLRAGIIYELMFLFNNDSDRAIHIFEQSIQLYPILLLSHPTQEFIYYGMFYDCSKMLPYINALLNVNSEEAQRRGAELISIAAISSKVLTPEASIEVQEIASRVLTGRALWRRGAARVYANNLIYESFAICLDALSMLLNDDDDDVCSIIGDIFENLREDHFILLHTFIKNYATSKSVTTNTRAFYNYLSEYGLLDPDWTLSVIMLTLHNPYEKPRSQWATPREEAIRIVTRIYTHPLTDVELRKQAMDVFDALMERYTGQALKVLSEWDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B939</accession>
    <name>A9B939_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_5226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07853">
        <property type="protein sequence ID" value="ABX07853"/>
        <property type="gene ID" value="Haur_5226"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5226"/>
    <dbReference type="HOGENOM" id="CLU_000315_21_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5288-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013663">
        <property type="entry name" value="Helicase_SWF/SNF/SWI_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08455">
        <property type="entry name" value="SNF2_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="574"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="859"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1021" mass="115387" checksum="A82A7ED9C8C18E83" modified="2008-01-15" version="1">MRALTHDQAVFEVAGSQKKPYTVTITSDPYGVITDCTCPHAAKGALCKHVVAAAHTLADHLIAHPLNPWRSVFASFQALPRRRPTPMRLVFSLLERGATWTLMPYTIAERVIPQAVMDDPVALHRHLMTKDVLIQAKIPRTPLHPSHVPSTAEAALVVANMIITVSHQFFYGAAFPLSTVLDSVVQFLPNTILFMGDDYNPFRRMVQVCSDHAQIHLHGTATADGITITPMLHVGDTRATLDTADVRMLHSAPPWAIYRTMLVRYDDPGNILTLFGRYQHLHIPAADYPEFIERYLMPLAEHTPLSGDLPQQALVAADPQPRVYLREHESTVFAELRFGYADHEVAYDQQLPAETMRYHPDHATILRIQRHSTSEEHAWGELLRHGLKRGPQAGVATLRSGTTVATFLLTHVPALVAMNFSIYGEESLLGARINRHTPSISLRVSSGIDWFDLEAVVRFGETELHLAEFRRAIRKRERYVQLADGSLGAIPEAWLDRYRHLFAFGDLHAETLRFAPAHSTVVDAVLEETDQVDQRFKERSERLKTINGIEAQALPAGFETVLRPYQKAGYDWLHFLYAYGFGGCLADDMGTGKTIQTLVFLQSLVSRGQTSASSLIVMPRSLIFNWQREIARWTPELRVLVHTDHGRADTTAAFANADLVLTTYGTLLRDHDLLATYQFSYVVLDEAQTIKNPVSQTARAVRALRSEHRLTLSGTPVENSIMELWSQFAFLNPGMLGSLDHFRTEFATPIERDGDAHAAQLLRRMVNPCILRRTKDQVAPDLPARNERILYCAMEAAQHKLYQRYRDQYRAQLLSLIDDHGMNDSRMKVLEGLLRLRQICNHPRLVESTFRGRSAKFEQLLETLAILQAEGHKALIFSQFVQMLTILREHLDQQNVSYTYLDGKTQNRAAVVDRFQTDPHVHFFLISLKAGGVGLNLTAADYVIHIDPWWNPAVEQQATDRTHRIGQEKPVFIYKLIVRESVEEKMVHLQERKRALADSIITSEQGIVKALTRDDVADLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B973</accession>
    <name>A9B973_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5260"/>
    <dbReference type="EnsemblBacteria" id="ABX07887">
        <property type="protein sequence ID" value="ABX07887"/>
        <property type="gene ID" value="Haur_5260"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5260"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_488147_0_0_0"/>
    <dbReference type="OMA" id="HNAIPSI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5322-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="558" mass="63644" checksum="1D59C9BB66538D6A" modified="2008-01-15" version="1">MYRNPVGRIYPQSISQDTLLDYSSLDLTDVAFPHPPNRPITTLDLSRNQIKRLSINSTDANLITRIILHDNEISDLPSDIRSFRNLQELYVAGCPLTTLPTWLEELTHLRILDIGDTDMMDCPPVLRRLPNLSTLALANLPWMKLPHWFGDLPITTLSLYGMPQCDLSVIAELRSLNQLFLTRMHYTQIPTWLQACTRLTFLDLSDNPITTLPPWLGKLSLETLILGRIRLERYPDWEQWNSLTTLDLVGCENADAVFSKPFPQSLHTLILDTSTITAVPECIRLLRSLRDCRLAHTTITSVPTWLFEEVALQSLDLSYTHLEFPALTKPSMLITFIFRGGRTSTWPSVFDQMPMLQLFDLEDAYFDDPLVQPLKTTYHDLKNFTSPRTYSGIPFALAMPNLQTLHMSAPWPPTSVDTLHMMLEHCPQLQAISLLGWNLDTIPTSMQSLSDLRSLSVPYNQITEVPIWLQGMTKLRSLDISHNRLTQIPIWLRDMPHLESLDLSGNPLQTFPSWLKDIPTLSEVAFVFPPASLQCDHVLPEFLAAGIRLDVRHPRDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B987</accession>
    <name>A9B987_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5274"/>
    <dbReference type="EnsemblBacteria" id="ABX07901">
        <property type="protein sequence ID" value="ABX07901"/>
        <property type="gene ID" value="Haur_5274"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5274"/>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3950">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_437971_0_0_0"/>
    <dbReference type="OMA" id="SDGEQMV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5336-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="8"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="347"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="519" mass="59162" checksum="1EB25173B1810949" modified="2008-01-15" version="1">MRLHHCTIGHYRVLRNLQIKFNNTDNERLGIDFLVGQNGSGKSTLLQAITFIIQQLEKGSDVPFRFYLEYELGSANAKQSIRIYNYELDEDSNQKKLDRARADTRTVNTEWQERHGSLEEILPRVIILTTGREQEWQTLLKPSQQSVTLDPLEVLSGSLADSDIHAQHEQRLLSERVGASIVFEPSAQSESQKITFVPTEALPLVTLCGVLAELSHNGILNSMKDIFEDVRIRQVCAFSLRFRLNLAGSNERREIQELGRKATRAVHIGSDWLLYFDLTDQQQSSIQDLLGDRGGAFAFYQQLRRLSRNAIAAERVLQEVNIFVKRGPKDEDPVKDREIAQNAPLHPLAWLSDGERSFIGRMSLFSMLRDQDQLILLDEPEVHFNDYWKRQIVDRLATLLEDGKCHALITSHSSITLTDVPREDIIVLHRGEQYTQSAGSPTLKTLAADPSDIIIHVFDSPYATGQYAVKKVKAILDEVGQRNNKQAQQKLKDLLNEVGPGYWSYRIRRVLYRMSNDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU92</accession>
    <name>A9AU92_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0360"/>
    <dbReference type="EnsemblBacteria" id="ABX03011">
        <property type="protein sequence ID" value="ABX03011"/>
        <property type="gene ID" value="Haur_0360"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0360"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_100_0_0"/>
    <dbReference type="OMA" id="MYEPSIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-363-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009594">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06719">
        <property type="entry name" value="AraC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="206"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="313" mass="34320" checksum="93DC2AF41074EC4E" modified="2008-01-15" version="1">MPMTQEHQTAWERQHRAANYAEISTRIAHILPSDGMIEPLPGVHVYRVSGPTEPIHGVTVPAFCVIVQGRKMVLLAADQYHYDPAHYLLTTAALPVVGQITEATPEAPYLSLRFALSPALISSVMAEVGVTPVASQASVRALAVSSLDGEFMDVVVRLVRLFNSSRDAQVLGPLIMRELVYRLLMSEQGMRLRQIAIIGGAEHRIMGALAQIQRDFHQPLRIPDLAQAVGMSVSGFHSHFKAVTAMSPGQYQQQLRLQEARRLLLSEDLDAASVGARVGYDDAAYFTRAYKRLFGAPPIRDATRMRAVVMAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC9</accession>
    <name>A9AUC9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0397"/>
    <dbReference type="EnsemblBacteria" id="ABX03048">
        <property type="protein sequence ID" value="ABX03048"/>
        <property type="gene ID" value="Haur_0397"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0397"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_470730_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-400-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="360"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="579" mass="62750" checksum="6D067E7A6B2B01C3" modified="2008-01-15" version="1">MSALTYPSLPSPFEMIGPCGKQSTHRRFFMAKKAGIPYLIWWESRIPEALRKQQMVVQIANQAGSEVAILDVQALSLQQLLDTAGSLPAPVAAQYALGLIETAEFNHRQRTALTTSNLYGPSLLDLGSQGTIVPKIDPRAGQQAGPVPAQLLPINEPASPQTDSYYIGALIAWMISGQFAPQGNPLAMLPAIDGNLRSILQRATVANPSQRPSAQALGQQIQDWLSGKVTPVAKKKPSQWAWLAGAITTAAIMWLVIYGLSRQDKVTDTEFGQAQIEQGTGDFQPGTSSNGLAMLGDIDGVEVNRIDDTRHPEIDMYLSIMRPTGVVTDVPRQNVKVFENNNQIEGFSWVNLSRVQDPLNIMLVIDTSGSMGPSKEGLTDGGLDAAKIAALDFIDHLPSNANVGLIHFGTLVTVDHSLTNDIGAVRQSISELKPEGQTAIYDALAISYTQLRRAKGQTFIVLISDGADTASKGDNYDSIVAKATKANIPTYIIGLTSPEFDGQLLEDLQRDTKAMIYQTPSKEQLGGFYTEVAQEVSGQYRASFNIPDTYKTGDEIMLKVEVNAGDGLLVTKERKYIHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUH6</accession>
    <name>A9AUH6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0444</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0444"/>
    <dbReference type="EnsemblBacteria" id="ABX03095">
        <property type="protein sequence ID" value="ABX03095"/>
        <property type="gene ID" value="Haur_0444"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0444"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_51_0"/>
    <dbReference type="OMA" id="YARTHID"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-450-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="351"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="594"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="713" mass="80670" checksum="48593F3E436CC531" modified="2008-01-15" version="1">MKRFAWLRRKELRPLIALLSVALVSIALLQWNYYQMRSMIQSQITAFNGMTQARLNMKRGYLIAEQVLNGNQTLLPQDAIAYLDQAILAVDDWQQGKNPVVVFDQLLPPDPPTQQALTDYRQHLVSFRALLLQHLNRPQEQAQTTIDRRIAFSELESEAEQLENRLYLDLELSIKRQAERYSLMLVGWLIFLVIIAGVVYRLLGLQRLAVAQLAASEKQFRAQYRGIPIPTYTWRCIDDDFILEGFNDAAMIITQGAITKFVNQSARIVYRNEPEILHHFERCQREKITLHQEIRYEFKLINQVKDLYVSYVFIEPDFIMVHTEDRTDRNQLQMQLIRAQKMESIGRLAGGVAHDFNNLLTAISGYTTLAIDSAQQGFPVVEELTEIQHATDRAAMLTSQLLTFARKQQIQPKIVNINDLIMSMEKLIRRVLPESIQWRTVLNVNIDLVLADIGQIEQVLLNLVVNARDAMPQGGNLLVETNNVAVDANYARTHIDVPIGNYVLFAVSDTGIGMTQEVQSRAFEPFFTTKSDHEGTGLGLATCYGIIKQHGGHIGLYSEVNHGTTIKIYLPRSEQAQLDDAPSLIQNLPRGTETILVSEDEPQVRAVLVRMLQGLGYSVLEALHGSEALALLQAQALGTIQLLITDMVMPQMGGFELSQRVAELDPQLKILFISGYSEHSLAQHQQLAQQPLLLSKPFSLATLAQTVRKVLDD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUN9</accession>
    <name>TPIS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Triosephosphate isomerase</fullName>
            <shortName evidence="1">TIM</shortName>
            <shortName evidence="1">TPI</shortName>
            <ecNumber evidence="1">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tpiA</name>
        <name type="ordered locus">Haur_1923</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AUN9"/>
    <dbReference type="SMR" id="A9AUN9"/>
    <dbReference type="STRING" id="316274.Haur_1923"/>
    <dbReference type="EnsemblBacteria" id="ABX04566">
        <property type="protein sequence ID" value="ABX04566"/>
        <property type="gene ID" value="Haur_1923"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1923"/>
    <dbReference type="eggNOG" id="COG0149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_3_0"/>
    <dbReference type="OMA" id="QEVCGAI"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000096506" description="Triosephosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <sequence length="250" mass="26351" checksum="F56B700892CFE6D7" modified="2008-01-15" version="1">MRRPLLAGNWKMHYGVSEGVALVEALSADLTDLTDRDVLVCPPFTLLGSLAPLLDGTAVALGAQNMHYEAKGAYTGEIAPQMLKELGCSYVILGHSERRQYFGETDALINRKAHAALANGLKPIVCVGEVKAERDSGQAESVVVGQLRGSLAGLSAEQLRGVVIAYEPVWAIGTGDTATPADAQAMHARIRAELAALSDQATADAVIIQYGGSVKPDNVDELMAQPDIDGALVGGASLKAADFIRIVRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUP3</accession>
    <name>A9AUP3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1927"/>
    <dbReference type="EnsemblBacteria" id="ABX04570">
        <property type="protein sequence ID" value="ABX04570"/>
        <property type="gene ID" value="Haur_1927"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1927"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_227070_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1956-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="1681"/>
            <end position="1775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="2748" mass="293889" checksum="87348CB705068D0C" modified="2008-01-15" version="1">MIRETSKLARVVSMCLILLLALQMLVYPHATSAAPSNQATSNQSPITSLIRDRNEQLDPYLQRVAAADPDLFQAAALLAVQDVFNGNLPEIAGDQAIEEQISYYLNRAALGLPMQPSNLDPAQSSAMQDDAYLWESNQAAIGTTWQMTARPDGDPRLFAQEFDALAAAQMPAVAPDSAFAPTAPVVEAAPQPALDPAETVVIPALPSSPVKLKSQTFIPSRPTSSQFLANLPSQQAEAEFSGLRIQPQVALNNPVQTPHAKLVVTATAPLQTNFGSIITYTVTVSNTGGQAASLVELSQRLPANSILQGSVNDCVLKDGEQLVCAIGNLNVNQSKTYQVPVLMKGNGTLISTLTVKDTFIVNPDTKPATAKISTNVNSTNRTQQDVGKIVIAAEQFTTIFGQTEASGAVEIGFKKDGKYTYHLRLGPNDKIKWDAVGTPTIIETYGNVAQIQENFPLFKGDFTIDVTKDKPFIKPSPTITPTIKHLAGFQLLGSAVISDVAILSGEAGFMTELKVSLPGITTTSTLTPTANMTTTTNLLRPSSILTGTNPITGTNPVSGTVKKNTLRVTGVIKPGGKGDAKINEFEMYFAGLKVKVKNATFSGDKIKVKQALLTMPKELGELTGIISEIEVTSNSINFGGVGVKIPLPNIYPLGKPITATNPLTPTSLLAQSVALSETGAYTPAVSFIKNSATIMYDSNDGFSLQIDSTLDLHVADNDRKIPVELKIDWKGQVKGTIKELKLKIAGHDLEMKEVEISNAGLKVSEASFTITFPSEKKDEPKPPAAGDPPAAPKEGDKKKEDKKLTITVKKVSITKQGFAIGEGAIATDLPDFGLGESIRFTKNKVKFVVTNPITSPAMELEIEGTLKVLIKSSEMETKFAAKWDKKGKFSGKLKELTLTVASSKLELKNVEFNTQRFATNSASLTLPPILGSTQIALTKVVIDENGLSFGDAAVKIPVKFTIGKQNGEPSPTNSVTISGTLGLDYKQDRSYSFVFAGKVSITLASQTAEAEGLVRIDKDGKVTGDVDSFELTIAGMKLAIKEASIENGTVKAREATFAIPKEWGGLSVSVYNIEISKEGFSIGGGSFKLPEIKVGDMSLTLEGTLKKEGNGWIIAAGGELKLPNAGGAGCSGLGVSVEIFAGSNQTVAMRIAPASVDALNEFQLRKVGVVLKCTIPLGASGFDLTRISGTVTLTSNVTKIEMSATIESKMGIGSFRAVTADGNMSMEYVKNPYKFEIGIGASMKIFSMFEAARASAKMRFTDGAVPFLFTAEMNINAVIARGNMKLTAWTKDGAFNLVGRIYGEVGVKRGALVDRCWRIWMPWPFDDQDVCLTLPGSDLFFGAGMEFGKFKRGNGDAWGFKASVNIAGANYGIYVDTSGRFSVGNVDDYRLIDAPSLRRAKYLHDLNAQQQLNRASLSAEDLALFNDYSFNNQEIIISTVEMTRPGDLMINMLRLSYDTDIQVSLVRPDGLRMTGSNAAGNLNFSETLVDPRDIRDPITHQGNAAAPPMLQTSLNVTNAALGEWKLVLNRAPAYDFIINVSGTIYGPPISDLVVINQNDGNNSVDLAWTQSTPFTSTATIYASQDTITDTASYTKTNNVMRPDGIMATETITVDVGTVTKFSGYPLVSFDYAEGLQNADETLDLSSLKSGVYNLWLEVNDGQNPPSRHYFPNTVSVLHAWEPTWTTTSVITPSYGSLDVAWTKHPDPDVDGYEIHVRNEADQFDEDSYIVDVGDALSQTITGLNAGENYELTIIGYDSGTGRTSAAAPITATPLIAPFSITANPTELSLDAGVAGTSNLTLASSINPYPEQVFIEVTSLPEGFAAHITTPIVTPTLAGVQSSVVLTPAASLLGGTYTVTLVALSNGTERYLDIPVVLNEPNFMLRTSVDDLTLTNFNSTSVAIDATYQFSEQDEIFVDVLDIPFGVDWAFTRSSFMPGEQTRLILTDTIDLEYGDYPITLLAFDNEHAYTKTLTLAVTGFYIEVAEDQAARPHEIAAPYILNIDGNEWDSPIEFSIEEPADEELFFVSLSSATAEVGQLVNLELSALIDTAPGTYEVLLHASSEGYTQTLPLYVTVEANAMATDLVMGYQGLIGGYIVAGESYSYTLAPKNISLNPALDVSVIDRMLENSLVTLTDAAGCGVATNGAATTLNCSLGDIAAGSQHNATTLTWQINPEVAEGTLISHTSELVINDTSLYSETSAIDNVGELAFTVERLSDLALTVDYDQMVNAGELTTLTATITNTGPSDAANVVVEFYLPAGTSLASADVGCIQEAELVRCEVGVMGVDQVETFAIQLAVGANQRDYLETLIAVDSDSYDEDLLNNSVYSFAEVVAVADLSMTIAPNRTTINEGEVVEYLLTIVNQGSATANNLQIELDLPDEADIVEVRIGNVLETPESLTLEPGATLTATVGILYPEDDAGTPIQVEAFAFADEANEVNAISVDVAVANLAPSGIFTNTLVVNEGEFGILAVMIDDAGNEYDPLTVAWDLDNDGAFDDSTTAITRFDARSFDGTTTRPVAVKILDDDGGETIVNGTVLVRNVAPTVAAGPDQFQIYDQQFTLDVALTDPFANDTKTASIDWGDGEIDTIPLAAQVTSTSASHNFSAIGNYTTKVCVTDDNQGQGCDEVVLYAMCRDNGLLVRVGQQNQQISIILENASGNLAIPMSMPLSLYHGNTVLQTFVLDQPLAVGASRTLNYTWANAPLSANLRVATDDDGTGTKSTDLCSGSVYKWAINTTIYAPVIMVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY8</accession>
    <name>A9AUY8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3942"/>
    <dbReference type="EnsemblBacteria" id="ABX06576">
        <property type="protein sequence ID" value="ABX06576"/>
        <property type="gene ID" value="Haur_3942"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3942"/>
    <dbReference type="eggNOG" id="COG4655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_341243_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3984-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="378"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="831" mass="89648" checksum="2D65AD38988BD33D" modified="2008-01-15" version="1">MNLSRMTRRVAQPVAGQSLVFSAILFFVMIAFAALAIDTGEAFSRQRQQQAASTAASIAGLESMNSEIDGTDGAVQQAIRDALAANGITNAVYINGDWGNLDPSQNYYRAFYTQRGSRVEYPVGSGGQVSTEFNGLRVEVRSARNTIFGQALGIDTLEVSAENKATLCQCATNIFPLAVATQKMTGMLPGESKPIAWTKNKVGSSVEKDYFVWAEWQTLSGFNADNRLKESLGGTGDVIKGVTEATAPPGYANASNNGVINIDDWIKVSDSTLRPNAASLATALTALKNKPILIPTFTKLSYSGTTGNEKYTSFRSGGFVKVMVTNFDSTGITIQYLNSNYTCPCVDVPQPPPPPEVKLALDQKLVWYLPSINTTSYDISLVVDISGSMQWCYDSQRTCSVDANARWYRVKDFLAKFSYKMLDVWNAPAGQNMNNASLFPGEALVGKGGDNRIAAVRFSGNAVTSSPSFGFVTSPAGSDQASVSARTTTMRSNMNSLISWITKANMSGSTSGGRGLREGIRYFDNVSAHTRVDRFGRPIKLVMVMLTDGLTNVMYEGPQVNSQNSQKLKHTRSGGYKYCKDPADPTANNVLTVGGDNYPITDLPEVQANCPWNGQGAGNGYAKAPIVSLVEVATQARNRVSPQRPVNIYAILVGDQGRYDLQDLRIDQIASPGGAFYAQNPNALDYALDAILDDLAQPCYERDATIIAAGAKVTVYDSSNNPVAGMSNMSADTNGTLLFTVPEAGNYSFGATRSVTSWSEFPLGSGETINPSLYPANYLPQLYNRLRGAEDTIVQNRIQFNIPAEADSLIDLGKYTMIIAEAQQNKALCPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUY9</accession>
    <name>A9AUY9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3943"/>
    <dbReference type="EnsemblBacteria" id="ABX06577">
        <property type="protein sequence ID" value="ABX06577"/>
        <property type="gene ID" value="Haur_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3943"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1381971_0_0_0"/>
    <dbReference type="OMA" id="PLNCANP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3985-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="19321" checksum="966EAE523AF2426C" modified="2008-01-15" version="1">MLKLQKKRKQAGQALVEFALTITVLFTFLSGIIDGALAFFAYQGLKGAAYEAVSYGSLFPLRSDGTINTQEIRDRLRYESGAPNNNSGLRYVNLFDLDNSGGPDPEGVLNQRIQISFVDGAVAGTSPLNCANPATLARQFCDIRVSVRYTYRSFFFAASIFGADTIDLTATQQQTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA6</accession>
    <name>A9AVA6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0536"/>
    <dbReference type="EnsemblBacteria" id="ABX03184">
        <property type="protein sequence ID" value="ABX03184"/>
        <property type="gene ID" value="Haur_0536"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0536"/>
    <dbReference type="HOGENOM" id="CLU_1924682_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-545-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14537" checksum="AE6F95C9CDD26677" modified="2008-01-15" version="1">MEIDAIRSHLATTYPSVTSAIITKGKRTIEGEEYETIEFVKKVGTKGLDLVAALEEIPPAWDLFDLFSTKPPVPIEKLLAGGLTFGEAMLMNLDTELSKRFEKKYNREESALCLHLAELPASADQDLPLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC6</accession>
    <name>A9AVC6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1974"/>
    <dbReference type="EnsemblBacteria" id="ABX04617">
        <property type="protein sequence ID" value="ABX04617"/>
        <property type="gene ID" value="Haur_1974"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1974"/>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_352945_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2003-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="796" mass="84139" checksum="0EA92A4B753C3309" modified="2008-01-15" version="1">MPWELQIHHLDIRSVGDATVILALDNNVVQRSVLIDGGRADAAPIVHNYLANTLNLNTLDVIVNTHYDDDHLSGLISLMATANTNVYDNVRCFDQGRPPNNSDYYANAPYRANGANTSFKRGKDQYGNEYIIRAAPKKYEQYVTEIARVNTRVRVTSTVNSFYLTTYDQNDIPTNPGNRNGYTDTILMQWNYYAAYPTINYPAGGLPNVVNFDNPAWLIGQEIMWNGAVYVPGAPTITCIAANKYVSRAGVNAAPAFISTASIYNGPNRRMSDADINDQENKNDNAKSLAFIIEFNNHRYYVGGDIERPQEDGFTNPNTGNFQLGIRDYLVPQSRIDQRVLSMKTSHHGSATASSRTFISQLMPMATFISTGSGNHHDHPAQSTVNTLDGYPEQPILGDPNQRLRHPPAPPQSPQQPNPYYLTGYQNVLVNPPLSYGGIASRTAGDPANNIAGHIKLTVTEAQSQLAIVGQVYRGVVAVVNQINQSQNQNVDPVPIATAATKIGTAAAVAAVLGVNDQGLQAIINSCAWVGNDINNLSVVGAAITAMNTFVPTNPNDPNDTAAEAAKNAAQNVDNGARVGHVGVGASTAIGYAVTGANANVISVATSNAGATQTAATAAGNAATYIYNHIANSINGPDVAYADRQAGFAAAAALGGVANGNLTAANATILACAHALAMPIGADPNNAALYAGADQIAQWITAVALAMNLNNNLACLAGAVASASYYLGNPADVDLAVSEALKAIAVANNTADQAGNAALQAATLVQNDLCNVQFDEIDPNPLNLAGFVAENIAVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVF3</accession>
    <name>A9AVF3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2001"/>
    <dbReference type="EnsemblBacteria" id="ABX04644">
        <property type="protein sequence ID" value="ABX04644"/>
        <property type="gene ID" value="Haur_2001"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2001"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_16_0_0"/>
    <dbReference type="OMA" id="MVVNIPM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2030-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <end position="51"/>
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            <end position="83"/>
        </location>
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        <location>
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        <location>
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            <end position="409"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX04644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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        </source>
    </evidence>
    <sequence length="425" mass="45936" checksum="9711D59917E8B8D7" modified="2008-01-15" version="1">MSLDTLKPTTTNPIDNWSHIVWKPRFFAIWLGQASSLVGSALTQFVLIWWITQTVGTAQALSLAGMMALLPQAVFGPIGGIIADRWNRRLIMISSDLISAISMVILIVLFATEQIQLWHIYTLMFLRSTMQAFQSPAATASTSQLVPPDWLTRAAGMNQIILGLMSVAAAPLGALAMSLFSLEGALMIDVVTALLAITPLLFYKVPQTRQATEDQASMWHDFRSGFSMILHHRGLTLMYGLTLLMVAVLIPTFVLTPLLIQQEFGGGVERVALMEGMGGLGMLIGGLMISIMQFSMRRIVLVLVMFALSSAMVGLAGLVPSSLFWVAVVLWFISGVTYTIGNAPIIAIVQTIVPNQMQGRALSLYSTMIGLAGPLTLPLTGPLSELIGIRMIFIGGGFIAALVCCLAFLSPSILQIEQTPIATHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL0</accession>
    <name>A9AVL0_HERA2</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="47" mass="4931" checksum="FF57190B0A714BD7" modified="2008-01-15" version="1">MSMVKQHREPHRTQSIGWLRAAVLGANDGIVSTASLLVGIAASNASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
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    <name>A9AVP0_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="RIARRFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4050-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="184"/>
            <end position="205"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX06640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="25455" checksum="6B377AE91336E9A1" modified="2008-01-15" version="1">MELRRYVAIIQRSWWLVLGVPLLVLLVSLISFQPDPQRYRVNAKFAITHAPVGGNEVLPDMNIYNSWQSTQFIVDDLPSVVRTEAFAQAISTWIASNRNIQLDAGAVKGMITAVEQEHRIATIIVDADTADQATAIAAGSIAVLDEQGLQWWDRAQWGTLAVETLELPTTASALSRWPQPITRLALRLVLALVAGLGLAFLRHYLDRTVREQSDLAQLNVPVLVAIPKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVU0</accession>
    <name>A9AVU0_HERA2</name>
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        <submittedName>
            <fullName evidence="4">Anti-sigma-factor antagonist</fullName>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4058"/>
    <dbReference type="EnsemblBacteria" id="ABX06690">
        <property type="protein sequence ID" value="ABX06690"/>
        <property type="gene ID" value="Haur_4058"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4058"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061564_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4101-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="252"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="370" mass="39610" checksum="C3D580BD8B5F37B4" modified="2008-01-15" version="1">MAETIAPPRQIEDMLQTSNEQRIKLFSLVEGLALLAVMLILLVAGNGQQVQIGLSICAIVGTMLAVTFALRRSRYVEWLIYVNLASITLMLSLTGPIIGEVDGSVWVLFQVPPLIATIVLNTSRATTVICVASSIILSIIIGGELAGFIPIKFLVPKSALLINFFCQLLVLGIIATTVHLLVGRAKRAFAVVAKTEAKLAQQLANERELALQREQLNAQLSQSLAEISQRDSQIQAEQAAQAALRDQLRQLSLPVIPVLKQTVVMPLIGEQLANSSEGIEETLLNGISQHRAKIAILDVTGVPTIDTELGRRLIQATAAARLLGVQTIIAGIRPEVAQTLVSLGIDFSSVTTVASLQDGVAMAIKRLGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVW4</accession>
    <name>A9AVW4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0554"/>
    <dbReference type="EnsemblBacteria" id="ABX03202">
        <property type="protein sequence ID" value="ABX03202"/>
        <property type="gene ID" value="Haur_0554"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0554"/>
    <dbReference type="HOGENOM" id="CLU_1822676_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-563-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="141" mass="15046" checksum="8520C4A5997D1D6C" modified="2008-01-15" version="1">MAKKGVAQYQSFAKRFRVRIDGATRDLLNEAALAGEGYAKQNMMANNSIDTGFALNSIHAVLVDGQGVDSSTTDLPDKHGDVVQRTSAGLPAMGDNTSAVGCAANYAIYIELRAPFLFPALDQVKADFGGIVQVVRRKRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW54</accession>
    <name>A9AW54_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2063"/>
    <dbReference type="EnsemblBacteria" id="ABX04704">
        <property type="protein sequence ID" value="ABX04704"/>
        <property type="gene ID" value="Haur_2063"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2063"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1319463_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2091-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="23504" checksum="1D2B0FA8C2D7EB32" modified="2008-01-15" version="1">MTSTEPRPIIPSIMLRRLAPEDTWAVHQLFAALHTYNASLDARFRLADAWPQVLDEYLQHVCDHPHRLTLLAWAEAEPVGLLMLDGHTDSPLFQHRQWAELVALYIVPAHRGSGLAARMVAAGAAWAQDHGYDRVQLYVTRSNVSARQFYARRGFTPVQEVWRLDVAPRHRLAPHDPDCEAIYAQGHHLLSTHQHGIGEGHDDLGSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW64</accession>
    <name>A9AW64_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2074"/>
    <dbReference type="EnsemblBacteria" id="ABX04714">
        <property type="protein sequence ID" value="ABX04714"/>
        <property type="gene ID" value="Haur_2074"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2074"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_1_1_0"/>
    <dbReference type="OMA" id="ETVWRVK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2102-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="233"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="349" mass="38601" checksum="B84C045C4E3AF88A" modified="2008-01-15" version="1">MTRCFEGVSMSEAPAIPMTILTGFLGAGKTTVLNRLLREAHGRKIAVLVNDFGAINIDAQLVVGIERNDIVNLANGCICCTIREDLLTATLALLDRAERPDAIIVEASGISDPLAIAWTFRSPALRPHITLDAIVAVVDAERIYEQREQVMQVVDQIAAADMVVINKIDLVPPLHIHAVMTWIQSIVPRARIVAAEYGDVPVQVLLGSGIYRIALLPNQEVPEPHTHHHDHEWQTWHYQTTQPFHLRRLQHALHHLPPSIFRAKGIVALAEAPDRQAIVQVVGNRASVQLSTPWGLTSPYSQLVVIGQRKRFDVVALRQQFHACLASGDHELCDQRPSANAWSHPDQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW93</accession>
    <name>A9AW93_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S45 penicillin amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2103"/>
    <dbReference type="MEROPS" id="S45.003"/>
    <dbReference type="EnsemblBacteria" id="ABX04743">
        <property type="protein sequence ID" value="ABX04743"/>
        <property type="gene ID" value="Haur_2103"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2103"/>
    <dbReference type="eggNOG" id="COG2366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011790_0_1_0"/>
    <dbReference type="OMA" id="THEVPNN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2131-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="810" mass="89412" checksum="1D1D0C469817B74E" modified="2008-01-15" version="1">MRRIWKFTRWILLGLLVLGLITGTGGYVYLRQSLPQTSGTIELTGIQQPVTIVRDQAGVPHIQAANYHDGLFGLGFVHAQDRLWQLEFQRRLARGELSEVLGPATIETDRFLRALGLVDAAVNAWNALDPASQQAIQAYIAGINQFIIHHDGMDLPPEFTILGFSPRLWQPIDVLLTGKLQAWSLGANWSAEVLYSQLIAQVGPERAAFLLPAASPDDPLILPDATYSAGSAPAPTMASSNFCGANADSCTSLLTRVEQLHQQFKLAGSYVGSNSWVLAGQHTSSGKPLLANDPHLAAQAPSIWYLAQIQAGELDVIGATLPGVPAVMIGHNRSIAWGLTNTGVDVQDLVIERLDQAGNAEYLGKPYPLTRRDEIIKVKDQPDHMLQVRSSRNGPIISDVDAELQATNQVLALRWTALEPTDTTITALLQLNLASDWQTFRAALAWYQAPMQNFSYADVNNNIGLQIAGRLPIRANGDGRLPVEGWNQQAAWLRLSEFDELPFSYNPPSGMLVSANNQAVADDYPLLISRSWAPAYRAQRIWQLLSEKPTFDQADMQRMQADQRSLQAQQLLPLLLTAQTTNPQALQALELLKNWDASLTSDSAAAAIYETWYLRLARAIVVDDIGEQLWRSYSYHEQFFALAIPTILQTNDQAWCDDQTTAEPESCALLIGRVLEQTLAELSAEHGGEIEQWRWDSIHQAVFPHAVFAGIEPLDSWFGHTIGNGGDSATINAGPTDRIDFVQYGGPIYRQIVDLGALDNAVYIQTPGQSAHILSTHFDDLLEPWQRGEYLPMRLPQPAETQTTLRLQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW95</accession>
    <name>A9AW95_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD/TfdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2105"/>
    <dbReference type="EnsemblBacteria" id="ABX04745">
        <property type="protein sequence ID" value="ABX04745"/>
        <property type="gene ID" value="Haur_2105"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2105"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044153_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2133-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="45"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="352" mass="39200" checksum="0EAA3462F0C584EC" modified="2008-01-15" version="1">MEAKSGLKKQLGSIKRQALATDQQALVTTSFLSEGQNLPLVVRPSVAGVDLAQWATNNLAWLTTQLHHYGGVLFRGFGVDTAQAFETVISAASGELLEYRERSSPRSQVQGNIYTSTEHPADQTIFLHNENSYQQAWPRQIFFCCTIEPATGGETPIADVRKVYQRLDPALRQRFIDRGILYVRNFGGGVGLDWRNVFQTADRAEVDAYCERVGMQAIWGENDHLQTRRMGRAVATHPITGDLVWFNHATFFHVSTLEAPIRDGLLAQFKPEQLPNNSYYGDGSPIEPEVMETLRAAYHAETIMFPWERGDVLMLDNMLVAHARSPFTGSRQVLVGMAHPTTHGDVANAING</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP8</accession>
    <name>A9AWP8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0651"/>
    <dbReference type="EnsemblBacteria" id="ABX03299">
        <property type="protein sequence ID" value="ABX03299"/>
        <property type="gene ID" value="Haur_0651"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0651"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1110222_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-662-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="28388" checksum="69CE5FE21DBF6FAF" modified="2008-01-15" version="1">MTFVIDLRWRKHHRPVGTGWDYRPKGIKPSSAVIHTTNGNRGSSFEAEADYLEASSGVGAHYLVGQRGQIAEILPPIYRAWHAGAAKDDWINSRSIGIECHHAVGEAWTHEQRAALAWLCQRLMADWSIVLGAIETHRFVALPAGRKPDPSDWTDRSFYDWRAALIAPVQPAGTYPVALELKVAWQSSGGLWHPSQFAPGYALTPFFRHPDGHQYQLFERSGARFTPQGTIEWLFTEEVERLKQWWRTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWQ8</accession>
    <name>A9AWQ8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal recognition particle-docking protein FtsY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0661"/>
    <dbReference type="EnsemblBacteria" id="ABX03309">
        <property type="protein sequence ID" value="ABX03309"/>
        <property type="gene ID" value="Haur_0661"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0661"/>
    <dbReference type="HOGENOM" id="CLU_2117645_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-672-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="114" mass="12003" checksum="35C3C9F2C4DF98ED" modified="2008-01-15" version="1">MIYFTYVATPDDGFLPGIPLANLTATHGEQMADWQLRSVAAAAMYQPTPAGLAYLAERLPEPDPAPEIPSEPEPPAEPEPPADPGPPADPEPEPPIDPEPTPTATSVRRRGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR9</accession>
    <name>A9AWR9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0672"/>
    <dbReference type="EnsemblBacteria" id="ABX03320">
        <property type="protein sequence ID" value="ABX03320"/>
        <property type="gene ID" value="Haur_0672"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0672"/>
    <dbReference type="HOGENOM" id="CLU_1508620_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-683-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="178" mass="19745" checksum="306FB66DB90B40CE" modified="2008-01-15" version="1">MTTTPITITLTETLDLPKHGQHTVQITVTPPSTEPHHLAPLLQQATMTLFQQLDAALIRVQQPPRYLCGALCSVLVCPFLGLYLRVPQSTPLETLLAETVVDAKGDAHQLWTVALMAVPPALVLPHIPVLIHAFSIQGAKSWREYRGEGDTLLAERLHEWQHAIPEPVRTDEHWLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV7</accession>
    <name>A9AWV7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0710"/>
    <dbReference type="EnsemblBacteria" id="ABX03358">
        <property type="protein sequence ID" value="ABX03358"/>
        <property type="gene ID" value="Haur_0710"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0710"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="VYAMREK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-722-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="158"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="240" mass="26559" checksum="14F228B946196CBE" modified="2008-01-15" version="1">MELIRVLIIDDHPLFRQGICWSLGQEKDIEVIGQAENGAEAIKLTETLSPNVVLLDINLPGLNGLEVARVLKRRAPRMGIIVLSIHDDDEQLFNAIKAGAAAYASKEIDPTQLVGMIRDVAHGRYVINESVMSKPHVATRVLNQFRELSNVANNSEDTSSMFAPLTSREIEILDCIARGLSNKEIANQLSISGQTVKNHITSILSKLQVNDRTMAVIHAIQQGWIKLGYDESRESRSRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXC9</accession>
    <name>A9AXC9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4217</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4217"/>
    <dbReference type="EnsemblBacteria" id="ABX06849">
        <property type="protein sequence ID" value="ABX06849"/>
        <property type="gene ID" value="Haur_4217"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4217"/>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037408_1_1_0"/>
    <dbReference type="OMA" id="IYYAYVT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4264-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="140"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="204"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="452" mass="48563" checksum="A1BBE9F700D81A2F" modified="2008-01-15" version="1">MTKILDIRPALDDVRAALDAGSIDQATLLVASLHPADAAAILDELESDELYEVFARLNLEHGADVLIELDTDSQVELAETLTSDQLSDLLEQMEPDDAADVLVELEPAQIAATLAAMDPEDSDDVRQLMEHDEESAGGLMTSHVVTLRDRLNAQQAIDLLRGLQPEDESVYYLYVVDANDGLVGVVSLRSLVMAPAQTLLSEIMDRNVITASVETDQEECARLLARYDLLALPVVDAQRRIVGAVTADDIIDVIEEEATEDMYRLANLPQDEDVEDSLFRSSRRRLFWLFINLPTAILAAWVVSQFDGTVEKVTALVPFMPIIAGMGGNAGIQTLTLIVRSIALGEVATGQGFRALGREVGIGAINGVAFGSAIGLLGWLWQGKPMLGVVAGCAMLLNLVSAAIAGTVVPLTLKLFRVDPALASGVIVTTVTDVTGYSCLLGLATILIRYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR4</accession>
    <name>A9AXR4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0830"/>
    <dbReference type="EnsemblBacteria" id="ABX03478">
        <property type="protein sequence ID" value="ABX03478"/>
        <property type="gene ID" value="Haur_0830"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0830"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-844-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="453" mass="50446" checksum="66DF10558644683C" modified="2008-01-15" version="1">MLQDHAIVIGASISGLITAHMLSHHYGRVSVLERDSLPEAGDFRAGVPQGRHVHLLLIRGARELETLFPGINQELQDLGAQAVDMINDCRYYLKNGWTVPQPTDLKTLSATRPLFDWAIRRRLLQNPKIQFLAQHDALNLIGNSRHIQGVQVRNRQDGSEQSLHADLVVDTSGRNSKLAEWLVELGCGKVSETVLDAKLGYTSRLYAKPEGWNEWKGLFVMQQPPTIPKGAILLEVEGNRWIVTGGGVNHAKPPTDEDGFMQWLRELPSPILADLLSKSQPLSPTSGYGRTENRQRHYDRMQLPAGVIALGDAVCAFNPVYGQGISTATLGAILLGTHLKEQDRGSAAWGQRFQQALAKNNQFPWEMASGEDSRYDSSFKRPFFSKLIAPYFDQINQASLNSNVVFSEFIKTIHMIGNPNALFHPRVFIPVLLSKIRPKYSDAVPNLPLQVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY13</accession>
    <name>A9AY13_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2339"/>
    <dbReference type="EnsemblBacteria" id="ABX04979">
        <property type="protein sequence ID" value="ABX04979"/>
        <property type="gene ID" value="Haur_2339"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2339"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_0"/>
    <dbReference type="OMA" id="SVWAIFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2367-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="388" mass="42872" checksum="ACA3BBDFBE8B06B3" modified="2008-01-15" version="1">MQAITIIGGGIGGLCLAIGLQQRQIPVQIYEAAPVLRPVGAGILLAPNAMNLLERWGLAETARQRGLCLSNLGGSEFGVLDAQGRSLLAGFDLNVMRERFGQELVTISRAALHQLLLEALPADCLHIDKRLVGLQQTADSVKVQFADGTTIETACLIGADGLRSAVREQIFPNQRLRYSGQTSHRALVEFDYHELGQPVAAEIWGAQLRFGYTPVGGNLVYWYATSLAAQGQRDVSPAAARELLLTQAHDLPTVVKTLIERTPDAALLRTDISDLAHLKNWYYGRVGLLGDAAHATTPNLGQGGCQAIEDAWVLAEMLERYEQSQLAFLHYQRCRIKKARTIVDTSWRIGSLVHLPYAWQQTWRNRLLRLVPRSFGQRQTNGIYELNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY34</accession>
    <name>A9AY34_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4284"/>
    <dbReference type="EnsemblBacteria" id="ABX06916">
        <property type="protein sequence ID" value="ABX06916"/>
        <property type="gene ID" value="Haur_4284"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4284"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030340_1_0_0"/>
    <dbReference type="OMA" id="YATDEVQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4336-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="522" mass="58149" checksum="D983F45312B3CE32" modified="2008-01-15" version="1">MQTYPCKLTSPARERGGIDTIITGGMPLSRRSGRGVGGEGKPLHIEESRPTMKRLLSQAGPVVIVALWLALLPISLFRLYATDEVQYFAYLRSVYFDGNLDFANEYGYFADLGMQKGDPAVYNALLKDRSSDPPLNPITGLYRNVAPVGSAILWSPWYVVADGLVGVGIFGDAPRDGFSQPYIIAVCLASACYTLFGLLLSYRLARRWVGMWAATLATLSIWLASPLIWYTYIQVPWSHGAGFAMVALFITIWLGPTDQPLLAQGSQRSWVRWLALAIVGGLMTLTREQLGLFLLLPAVEGLVAYASLIRQGQWLQVRQLLAKHVFFVLIFALSLAPQLISYNILYGQPKPSGTVSGKLNLISYKFLHTLFDPRRGAFMWHPLLLVGLAGLIWLWRKDRLLTGLLSLGLFAQIYLNGAFGSTWHLQGSFGFRRLIECTPIFIIGLALLIERIRWPKAAIASLALVFIVWNGGLIFQAATDREIRGPGLRWNTMLADQLKVPQLVWQKADQLLFNRCEVVKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY43</accession>
    <name>A9AY43_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphohistidine phosphatase, SixA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4293"/>
    <dbReference type="EnsemblBacteria" id="ABX06925">
        <property type="protein sequence ID" value="ABX06925"/>
        <property type="gene ID" value="Haur_4293"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4293"/>
    <dbReference type="eggNOG" id="COG2062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084603_3_1_0"/>
    <dbReference type="OMA" id="SQMFWLT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4345-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101006">
        <property type="term" value="F:protein histidine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004449">
        <property type="entry name" value="SixA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00249">
        <property type="entry name" value="sixA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="18839" checksum="1264C6ADF8661D3C" modified="2008-01-15" version="1">MILYFVRHGIAEDWAESGLDQDRRLTERGRKRIRQCAQALRLLEIKPQIILSSPYPRAAETALIIAEALGTDPPVLKEQLQPDGANSHLLTECLNPDWNEVMIVGHQPNLSEYVAHLAGYGTNLIFKKGTVCRVELQGEHGQVSWLLPPKVLIALAEARQAKPAKPAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY72</accession>
    <name>A9AY72_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4322"/>
    <dbReference type="EnsemblBacteria" id="ABX06954">
        <property type="protein sequence ID" value="ABX06954"/>
        <property type="gene ID" value="Haur_4322"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4322"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_0"/>
    <dbReference type="OMA" id="GLERMKY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4375-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="41866" checksum="12D6907628DCE97A" modified="2008-01-15" version="1">MADLRPAILGGTPLATSPIRLVRPVLPEFATLAADVEQTLISGMVTKGQHLVAFEQAVAAHLGVAHAIAVSSCTTGLALVYRALGLNGPVIVPSFTFMATVSALIWAGATPRFVEIDPTTTNIDLDAVRAALTPDVQAIVAVHNFGNPAAIAELEAIAADAGIPLIFDAAHGFGAQYDGRPVGGFGTAECFSLSPTKLLIAGEGGIVATNNDELAHKIRTGREYGNDGKYGSDWAGLNARMAEYNAIMGRYSLEQLEQAARQRNQYAALYWAALFATPGIDFQKVRPNDRCSYKDYSITIEASEFGISRDLLSKALAAEGIDSRAYYDPPVHRHAAYAQFAPTEGSLPKTDWLAQSSLSLPIHSEMEFSTIETVCAAIKRIQLFGEEIIAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY74</accession>
    <name>A9AY74_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4324"/>
    <dbReference type="EnsemblBacteria" id="ABX06956">
        <property type="protein sequence ID" value="ABX06956"/>
        <property type="gene ID" value="Haur_4324"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4324"/>
    <dbReference type="HOGENOM" id="CLU_697888_0_0_0"/>
    <dbReference type="OMA" id="LADYHEV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4377-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="328" mass="37823" checksum="08775DF04ED33F8B" modified="2008-01-15" version="1">MSEPAVELLLAAWSSQPAANLTQLCAACSPNDWKVLAHLADYHEVEGLLWSVLRHQALPATLAEHWRERYYLAALRNDLRLEEFQRIQQLLNAESIEVALLKGMAFAPTIYRSLGQRQMGDIDLLVQRADLQRACAVLFAAGYGLSQYTVQTWPQQRRSGGEVRLQTPSGATLELHWWLFAGLWSRWAGLHTYPAWQLRQAHYQTFTLPVLEPISQLLHTAHHLAIGNQYGAGIGRMLADIDRLITAYAFDWQQVWHEAQRWGLAHMLWGGLRLAEQWFNSAIEWHWQPRTWRRALLERCLPSQKLLLGADPRLRRRWRYAILASALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYA2</accession>
    <name>A9AYA2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4352"/>
    <dbReference type="EnsemblBacteria" id="ABX06984">
        <property type="protein sequence ID" value="ABX06984"/>
        <property type="gene ID" value="Haur_4352"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4352"/>
    <dbReference type="eggNOG" id="ENOG502ZRM5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3011472_0_0_0"/>
    <dbReference type="OMA" id="KFIAQER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4405-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="62" mass="6602" checksum="B1E903C2F650FEDB" modified="2008-01-15" version="1">MRRFGAILAFLIGAVVGLVGGAALLAYAYQVAGLYPPDDATIKFIAQERGWFDPNTEETPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB0</accession>
    <name>A9AYB0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0844"/>
    <dbReference type="EnsemblBacteria" id="ABX03492">
        <property type="protein sequence ID" value="ABX03492"/>
        <property type="gene ID" value="Haur_0844"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0844"/>
    <dbReference type="eggNOG" id="COG3872">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038140_0_0_0"/>
    <dbReference type="OMA" id="LFQYHGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-858-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010787">
        <property type="entry name" value="DUF1385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07136">
        <property type="entry name" value="DUF1385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="33450" checksum="496AF0C41A1AFE9A" modified="2008-01-15" version="1">MAERFPYGGQAVMEGVMMRGLHRASVAVRSPAGQIVIRDRELNLERRVFWSRLPLLRGIQLLGDALVIGMWALMFSASVTDDQAEQPLSKGQTALLVTTSVGISIALFFVLPLLVASGIANWANLGIYSRETIEGITRLLIFVGYLVLVGRTAEIRRVFGYHGAEHKAVSAYEAGCPLTVEHVRPFTTIHPRCGTTLLLIVVVLSIPVFALLGTFPFWLRLLSRIILVPFVAALAYELMRLTASKATNPIVRGLMTPALALQRLTTREPDDAMLEVAIAALARVLAADGQTVESQPIAVDIRPALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYS1</accession>
    <name>A9AYS1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2409"/>
    <dbReference type="EnsemblBacteria" id="ABX05049">
        <property type="protein sequence ID" value="ABX05049"/>
        <property type="gene ID" value="Haur_2409"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2409"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_3_0"/>
    <dbReference type="OMA" id="LHQRERF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2437-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="7"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="253" mass="27306" checksum="D13C720577027418" modified="2008-01-15" version="1">MQSLRDTWLLFKHYLTMTMRNPVMVIVGLFQPVVQLLLFAPLLEPIAGTEGFPEGGAIGVFTPGLLVMLGITGSLFVVFGFIAELRAGVLERMRVTPLSRLALVLGRLLRDVTMLLLQALVLVGVAWLMGLRADPAGVALSLLIVVLLGLLVSSCSYAVALILQDENTVASLLNFLILPILLLSGITLPLTLAPDWIRNVAGVNPFAYAVDASRALFIGQLEHPAVWQGFAVMGVLSFLGVFWAVRSFRQGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZD7</accession>
    <name>A9AZD7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2441"/>
    <dbReference type="EnsemblBacteria" id="ABX05081">
        <property type="protein sequence ID" value="ABX05081"/>
        <property type="gene ID" value="Haur_2441"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2441"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_749282_0_0_0"/>
    <dbReference type="OMA" id="IMANAVM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2469-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="243"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="280"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="449" mass="49542" checksum="9349814C19A3CA8C" modified="2008-01-15" version="1">MSELVVVENYRFRYAQALVELGPWSFGLAQGECVLLLGANGAGKSTVCRLLNGLIPYRYAGQQTGSVSIAGHATEQLNSPTWSQLVGSLSQRPANQILGHTVARDLAWSLAQQGLPRPTIAAKVSELAERFGLLELLQRQPQSLSGGEIQRLALANLLARNPILVVLDEPCAALDAAGVQLVRHVIQQLQQQGTTVVIAEQRPQLLRDLATRALSFEKGQLIYDGTVSAIVQNEEWSVVQNKLKIKPMLTWHKLGYKRNQRPIFANFSEQLDCTQVGLVGPNGSGKTSLLQLTSGVLRPQTGWICYQQRPINQQRADQRATYLASPPQDLRSFFYRPTVAEELTCADPTWREQLIERFGLAELLARSPFQLSGGEQRRVALACALLHKPKILLLDEPTAGLDYAGRWQLRELLQTLAQQVSALISSHDLAWLASLTSRWLRLPQATAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZF2</accession>
    <name>A9AZF2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Silent information regulator protein Sir2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2458"/>
    <dbReference type="EnsemblBacteria" id="ABX05096">
        <property type="protein sequence ID" value="ABX05096"/>
        <property type="gene ID" value="Haur_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2458"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_0"/>
    <dbReference type="OMA" id="QCTACGN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2485-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="18274" checksum="957771408F88CF85" modified="2008-01-15" version="1">MLDVQPNAGHVALAQLEQHIPSVTIITQNIDGLHQRAGSTRVIELHGTINTVSCSAAEHGSLAWPDSPNLPFCSVCAAPLRPDVVWFGERLDLAKIQAAELASQTCDVFLAIGTSGVVAPAATFPMTARAHRARLIDLNLEDTPLSRHARHRLRGTAAQLLPALLAATWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK3</accession>
    <name>A9AZK3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2509"/>
    <dbReference type="EnsemblBacteria" id="ABX05147">
        <property type="protein sequence ID" value="ABX05147"/>
        <property type="gene ID" value="Haur_2509"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2509"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056890_0_0_0"/>
    <dbReference type="OMA" id="PRTYEQW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2537-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="194"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="40316" checksum="52A92CEA585B09E1" modified="2008-01-15" version="1">MPLPRIGLFADTALSTQKYHLEEHMQAVAQYLKRPATLDDIPAATALINRCSMEEANVIELDEAELGVEWQSSNFNLATDSLTIWDGETLIGVAGVFSEEPYVHGYGWTRIHSDYAADNIQQQLLDWLDQRVSQDIAKAPSDAAVSLYHGVLSTNHEVAKSLTNHGYSLVRHFWRMVIELADYTPQPVQLPEGLIIRPYDPATELPAVIHAVRDSFRDHWGYVESPFEQELKQWQEMIAREPNYDPALFYVICDGDQIAAIALCWKHITEDPKMGWVGTLGVCRPWRRKGLAKALLYHAFNEFSSRGQERVGLGVDTSSLTGATKVYADVGMKPVRQFDRYQKVLRPGIEIGTETAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZW0</accession>
    <name>A9AZW0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase with TPR repeats</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4533"/>
    <dbReference type="EnsemblBacteria" id="ABX07164">
        <property type="protein sequence ID" value="ABX07164"/>
        <property type="gene ID" value="Haur_4533"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4533"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388716_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4588-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="425"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="710" mass="76382" checksum="B5D0A335A7BD7CBB" modified="2008-01-15" version="1">MSGQATFQQGRYQVRNELFRDECGVMYLAVDGKMAGREVALRQLNDGVLDATSLQRLAQLNQAALPSVYDLFEEHGQRYLVLEYPRGQTLADVALGPRLREGVVLAWAKQIAEGLRYLHSQGFVHGDIQPQNIVLQDGRRIKLLGGLPAGCPKNAGSRYAAPEIWSGATATPASDIYALGATLHHLLTGTDPNTQPLMAFAPPDVRRPDLSPAVSHAIVKALSQQPQQRFANIEQFVVALSQTSSTHESAGDLPVIGFTPSILPSTPADGPTQRYVPSESSPIPVPPGRGSTAQYDQAMLEQLLIPDRDVGPAPSILPKRPAQQNSRAGLIVLGVFIGLALLAGAWLLFKPKSNVFVNATQVANNGLPTVTRDEGILLSDSAKTATALAAIPPPTQIPTLDVPRATADAIQTFTVATQLAFDDALDARYQRGMAYEETGQYGLALSEYDEILRQDPTYKDTQARRDRIKIFLDATATAGPQQTTIAGGTATAVAQPSPTALPATPTATPIGQIVGDSFDGSTLDPRLWAGETRDGTIQLTNGELQLAATSATCYPVVRTITDTLFPVNNFTLSVTFRYSDVTALGTGFMLADAMATPCGDTDRAGTSWGGIWQDGTQGLIVEFHRDQTADNELKDIRLPYSNGQIDTTEHTLIIQQRNGQQTFILDGNVLFTEQAGAQPQVLWFGNPSRTAIASPWTVLNILSVDLREEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B032</accession>
    <name>A9B032_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1091"/>
    <dbReference type="EnsemblBacteria" id="ABX03739">
        <property type="protein sequence ID" value="ABX03739"/>
        <property type="gene ID" value="Haur_1091"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1091"/>
    <dbReference type="HOGENOM" id="CLU_1048756_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1111-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="29280" checksum="77DD1ED45B72AFD5" modified="2008-01-15" version="1">MSSEAWRLGVAGQWQRLLLYPGGLSALVMVSLGWLVWRWLSPRQNPVGTEHPFDWLLVPLPLLALSLWPFAESSELRATLDLLSYWLLLDAPLLWAIGQDWRNGALAGLRAARWLVGLITGWPLLGLVGWIIASLHGGLLPNDLLILGEGWLGWLALALWLAGLLPYLQLGAWETAPTQGALAWALGARRLGHLALLAWLLQAQFKLAWLGSIWGFGALLLGLWLLLLGLTSWLRRYSQAQVGAWLWSGALVGLLGFGLSSWLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9B045</accession>
    <name>A9B045_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1104"/>
    <dbReference type="EnsemblBacteria" id="ABX03752">
        <property type="protein sequence ID" value="ABX03752"/>
        <property type="gene ID" value="Haur_1104"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1104"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_0"/>
    <dbReference type="OMA" id="LDKYATH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1124-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23912" checksum="69E8C39FA5B1F861" modified="2008-01-15" version="1">MQEQIRVVLVDDHVVVRVGLRAFLDTQPDIEIVGEAASGEEGVQVVSQVLPDVVLMDLLMPGIDGVEATRQVRGASPHTQVIVLTSYSEDERIFPAIKAGALSYLLKDVGPDALVAAIRAARRGEATLHPMVASRLMTELTSSRRSPLDTLTEREREVLTCIARGMSNAEIAEHLVIGERTVKTHVSNILSKLHLQDRTQAAIMALRERLVPLDDEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F4</accession>
    <name>A9B0F4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_2625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2625"/>
    <dbReference type="EnsemblBacteria" id="ABX05263">
        <property type="protein sequence ID" value="ABX05263"/>
        <property type="gene ID" value="Haur_2625"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2625"/>
    <dbReference type="eggNOG" id="COG0362">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_4_2_0"/>
    <dbReference type="OMA" id="VIMVKAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2653-MON"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="181"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="483" mass="51850" checksum="F64E33C7B749A840" modified="2008-01-15" version="1">MDATADIGLIGLAVMGQNLVLNMNDHGFVVAVYNRTTSKVDQFLANEAQGTNVVGAHSLEELVGKLKRPRRVMLMIQAGSAVDATIDQLVPLLEPGDIIIDGGNSLFTDSNRRTADLEAKGLLFIGTGVSGGEEGARHGPSIMPGGSPAAWPHVQPIFQAIAAKVDDGSPCCDWVGEGGAGHFVKMVHNGIEYGDMQLIGETYDVMRSLGLSADEMSSVFGEWNAGKLDSYLIEITRDILAFRDSDGAPLVDKILDSAGQKGTGKWTVVSALDNGIPLTLIGEAVFSRFLSALKDERVHAASAISGPADQPNVDRAALVNDLRDALYAAKIVSYTQGYMLMRAAAKEQGWNLNYGGIALMWRGGCIIRSAFLGKIEEAYRNNPELVNLLLDPYFSNEVQQSQAAWRRVIAHAVLAGIPVPALSSALAFFDGYRTGNLPANLLQAQRDYFGAHTYERIDAERGKFFHTNWTGKGGTTTAGTYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0J1</accession>
    <name>A9B0J1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC transporter, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4578"/>
    <dbReference type="EnsemblBacteria" id="ABX07209">
        <property type="protein sequence ID" value="ABX07209"/>
        <property type="gene ID" value="Haur_4578"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4578"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064090_3_0_0"/>
    <dbReference type="OMA" id="ELYTFGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4633-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="270" mass="29588" checksum="69A0EF78833F51F9" modified="2008-01-15" version="1">MLRNIFTKIMYERRRSLVWWGLGIILLIAMLMGFYPAMRNPATSEQLTKAMEAMPKEMLAAFGVTDVANLITPAGYIQGRLFGFMLPLIVMIFTIGLGSRAIAGEEEARTLDLILAHPIRRSTIVWQSFAALSVLAIAMGLITWLSLWIGAVLLDMEIGVAELGAASFNMSLMALCFGSIALLIGAATGKRAMSMAVATILAVIGYFANSLASVIDWLEPFQKLSPFYYADYNQPLKHGFHYLPILVLGGVIVLCGFAAVKLFERRDVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0X3</accession>
    <name>A9B0X3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ordered locus">Haur_1195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1195"/>
    <dbReference type="EnsemblBacteria" id="ABX03843">
        <property type="protein sequence ID" value="ABX03843"/>
        <property type="gene ID" value="Haur_1195"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1195"/>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_0_2_0"/>
    <dbReference type="OMA" id="HLEGHIY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="31"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="148"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="354" mass="37711" checksum="59EE13A7B1EE5FE1" modified="2008-01-15" version="1">MSQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHILTITPVINTVLAQVPGGWSAINAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHLEGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLNDHGDYRLLGQTRDDAVGEAFDKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLGERMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALRERLSATAKPIPVAYPPIWLCTDNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Z3</accession>
    <name>A9B0Z3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2633"/>
    <dbReference type="EnsemblBacteria" id="ABX05271">
        <property type="protein sequence ID" value="ABX05271"/>
        <property type="gene ID" value="Haur_2633"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2633"/>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008952_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2661-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="330"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="786" mass="89302" checksum="19310D4477E02A6E" modified="2008-01-15" version="1">MLTASEQLVTAIKLRELGLQREQALATYAEISQRLATIEDPHARINLLHEQLQQLTFAKQPLHPSITNMRLLSDPATPASSELTAWWSAELERELASGQLRAELVSIFGALFQEWLDHAEVAASYPEQAQSLVTQINQPSMATTHGVVLDAIFHDQFDPETRSELSKALQAEPDEIDSDTLCAILRRIAKDSFYSAATRSEARQILGDPIMRKELADALMIVRTQLADWRWPKSGVTAVAQFARTKWRLFLQEDLLTACLHHVVAEHWQEYFAKFCRVNSSLPLKKLKRIAQDRGYDRDLNKLIAESYAVSKSVNLWHTLRRPLALDAAEQLELYGNPQSIFASRAAEITRLQQWSQLAEYDSNYEHNLEVALRLINAEIQLGLHATPDQAIYVLKTDFRDYYPSLNQQFVLDVLQRMGLSQQQIGFFAEYMAVPLQVNQQATQQQIGIPNHRPISDILGELVLRLMEQYLELHAHVQIVRFVDDLTIIATDPDEMRKAWQALQTWCTSCGLNLNEQKTGAMAINDQLPSELPHQAPHWLFLTLDAQGTWQLDHSLIGEYINQTAQTITNTPAILNKIEVYNGACTYLCQAIGLRVNLGASHREQVRTTLWRYGQQIIQQGSMVAYIGDLIHQRLNNSVSLPEGWFHWPITAGGLGIQQPLIIAHSYQQAWQAATAPSVPTERLAWWQQNDNPWGKFYRHWLQKLAATEPEANSVLTSLTDDFIARGGEVRNGEQHGLSAYWRWVLALYGPQMLERCGSFRFLFTELVPLQLIARKSAHKLHGAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B118</accession>
    <name>A9B118_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX05296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2658"/>
    <dbReference type="EnsemblBacteria" id="ABX05296">
        <property type="protein sequence ID" value="ABX05296"/>
        <property type="gene ID" value="Haur_2658"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2658"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_025443_5_0_0"/>
    <dbReference type="OMA" id="ISIFELT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2688-MON"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
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        <location>
            <begin position="21"/>
            <end position="41"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="46476" checksum="CE706A5433B471DA" modified="2008-01-15" version="1">MAAINPWAKRLYQTGRWASNVVIWLVLWISCVAIIFLMIRYFSGAEWLSNLQGSAHFVAEFGMRLLMAAPFTLWLLLMLRPIRTRRWVVSHILKLTQRLRRQPKPQLEPAIDQLDREVQPTTNPTMSAKPLSRRRFLVESGLVGGVVGYAMLIEPYQIQVREVNLPIANLPERFRGMRIAQMSDLHINAYTTSADLARAVAQINQLNPDMVLLTGDFVDWDARFADAATEPFRQLRAPEGIYSVLGNHDYYSGKIDIIKQAIQRHDLGLLVNQHTILRRGADQLVLVGFDDPRHNRSGGPRLSPESINPEAALKGTPKNVARLAMVHNPVIVPHFVANYQLDVILSGHTHGGQFQVPILTDQLVGNAEYFVRGHYDLGKSQVYVNSGFGFTGPPLRFRSAPEITLINLVNAKA</sequence>
</entry>
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    <accession>A9B1A6</accession>
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        <recommendedName>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="gene ID" value="Haur_4662"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4662"/>
    <dbReference type="HOGENOM" id="CLU_1213483_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4719-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="InterPro" id="IPR019545">
        <property type="entry name" value="DM13_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10517">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51549">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="124"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="24596" checksum="8C295DDB147152C5" modified="2008-01-15" version="1">MKLRYSTTIIIFGLLTACGTAPTKVDEPFPTTSSAAMATAQPTMDSMMQTDALTMTDDMMQPTDAMSMTDDMMQPTAMPTADDMMQPTVIPTADTMIQPTVEPTTEARVEPTTVPAEPVVLGSGSFRGIDHKSGGIATLYQQPDGSNLLRLSDFFVEAGPDMYIFVAKAAEINQPSDLQAGYLELGKLKGSEGNQNYSLPADFDPALYANVVIWCEKYQVLMAVAPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1C2</accession>
    <name>A9B1C2_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX07309">
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        <property type="gene ID" value="Haur_4678"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4678"/>
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    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732327" evidence="1">
        <location>
            <begin position="25"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="338" mass="36920" checksum="291EC8DFE7A8395B" modified="2008-01-15" version="1">MPKRVMLILGLLLGLTLWPRAASAHEVCFPEDQSPHCLSDPFSDYWEANGGLPVFGYPITTVNREQNRETGKVYRTQWMERNRFELHPENTGTPYEVLLGLLGKDRLAQLGRQPDSAESGPKAGCLWFKETGHNVCDQGNGIGFKSYWQANGLKIDGLDAYARSLQLFGLPLTEPKMERNSSGDLVETQWFERARFEWHPNNPNNFKVLLGLLGKEVRGTTPPTTPPTTSPPTTANCTMNAPAVAEGAQAWVVYPEIASNTTQTVCVRLTISAKPKSGATATVEIDLASGTQSLIGLTDSSGIATIQFKVGSQSSGRRNDVRASFSTGQTATTSFIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1W9</accession>
    <name>A9B1W9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MLTR_LBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2773</name>
    </gene>
    <organism evidence="2 3">
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2773"/>
    <dbReference type="EnsemblBacteria" id="ABX05411">
        <property type="protein sequence ID" value="ABX05411"/>
        <property type="gene ID" value="Haur_2773"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2773"/>
    <dbReference type="HOGENOM" id="CLU_082999_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2804-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MLTR_LBD" evidence="1">
        <location>
            <begin position="116"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="32828" checksum="9DB481626F8349FD" modified="2008-01-15" version="1">MTVAKDRAAQINATFIEAAESIRIQRKRAFEDQLWHKKQPKQANPFSQQAIWAEYPTYKRLLEQRAKNQVAEHVVRGIASLLECPIHERNYLLRSAGYAEDPDILSGDALEAQLAQLQSLLDILQYPAFLVNQVWDILAINQPMVHVFQHFLGLNFERIPVEHRNILNFMFDPVNYSARKILSKGGLQWERVARNYVYNFQQANRACQFETWYQAKVASLMQLPDFERIWQSIDPSIKAHDMLSQGQTDNLVYGLRTIYISESDTYAYPRIHAYVDALGTKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B217</accession>
    <name>A9B217_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4736"/>
    <dbReference type="EnsemblBacteria" id="ABX07367">
        <property type="protein sequence ID" value="ABX07367"/>
        <property type="gene ID" value="Haur_4736"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4736"/>
    <dbReference type="eggNOG" id="COG1943">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101320_5_0_0"/>
    <dbReference type="OMA" id="SAQTIAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4794-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="78" mass="8714" checksum="AEB62F17E45E5AB4" modified="2008-01-15" version="1">MMPDHVHGFRSAPPTTAPMVIGKTLKRILAVDVFRTFLTLKRRHFWGSGLWTDGYYYGSAGTVSAQTIAMDIANQKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B232</accession>
    <name>A9B232_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4751"/>
    <dbReference type="EnsemblBacteria" id="ABX07382">
        <property type="protein sequence ID" value="ABX07382"/>
        <property type="gene ID" value="Haur_4751"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4751"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021290_2_0_0"/>
    <dbReference type="OMA" id="WDLTDIY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4809-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="207"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="605" mass="67376" checksum="E7FED93252BFAFAD" modified="2008-01-15" version="1">MTTAATVPSRQEVALADTWDATKVFASDAEWEQALDAYAQSIADIEQYQGRLAEGPATLLAALNYSDQLNERVGKLYIYASLFYSVDTTDQVAKAKMDRVLGVYSRTMASSAFIEPEIIAIGFATLKQWQAENADLARYGQYFHDVERRQAHVRSAEVEQVLGLVSDAFDSASSTHRILTDADLAYPAAHSTNGLELELTQGTIGLLVTDPDREVRRTAFENYSDAHLANKNTMANCLATCVKQHVFNARVRNYSSALAAALGENNIPTDVFHQLVATVRKNYPTWHRYWRLRRQALGYDQLHVYDIKAPLTTKKLEIPYTEAVDWIITGMQPLGEGYTSVAKRGLLEDRWVDIYPNKGKSAGAFSSGWKGTPPYILMNYNNDIFGMSTLAHELGHSMHSYLTWQNQPTIYSNYGLFVAEVASNFNQALVRNHLFNTNQDPDFQIALIEEAMSNFHRYFFIMPILAQFELEIHERGQRGEPLTAATLNGIMFDLFREGYGEEVVPDADRMGITWATFSGHMYANFYVYQYATGIAAAHALAEGVLAGKPDAQANYLAFLSAGSSLAPLDALKLAGVDMTSAEPVEAAFRVLASYVDRLEQLLGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B255</accession>
    <name>A9B255_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Penicillin-binding protein transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4774"/>
    <dbReference type="EnsemblBacteria" id="ABX07405">
        <property type="protein sequence ID" value="ABX07405"/>
        <property type="gene ID" value="Haur_4774"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4774"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_1_1_0"/>
    <dbReference type="OMA" id="VERANIP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4832-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_dimer" evidence="3">
        <location>
            <begin position="50"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="361"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="750" mass="81256" checksum="BE1B43D6EB3E925A" modified="2008-01-15" version="1">MRGRLIGLRVVSLIIFVVLLARLQQLQFGSSAATSRASIEQNITRRDYVAPQRGEIFASDGTTLLAASVPTSILGIQAESLPRKRAERNAVYMRLSMLLPFSDTFTLSPTTKLQEDPALAAAIYGISPILPADTNFAPAQSITVTVPMGKALTALQLSQAYTDVITLQPGVEKVLAKANLPGYLVVPVAKNIPDDVALAIRENALALPGVRVVDGFQRDYPLSAEVQSLSHLLGYMIRINDKQLARYNPTNDADGPRQYLESDLIGVDGIENYYESTLRGKLGTNQISVDVSDRIVGEPTVLQPMEDGKNLILNIDMDLQRASEAILQKWLDVADQRRVRLANTPGKDQAKYASYDPINKGVIMVMDVNTGAVLASVSLPAYDNNAFNRGEVEEITDLFTDEENTPLLHRAIAGKYPPGSTFKQFTAAAALDSDIINPGTQIQDPGFLIVRNEYNEALTNQYPNSNRRANGLINVSDALKVSSNVFFNTVAGGTDYVTNLKPTDPQIKGGLGIDRLYETVSGEFGFDKLTGIDLPGEDSGIIPNKEWKKQRRERWGVGDTYIAAIGQGDVQVTPLQLLRATVATANRGSVYQPQVVKAITDLNRTDTITLTPVIEHTIELAPEHWAIIREGMRRSVRDPDAYNRIANGNNKPAGAILTDLDRLDLAGKTGTAEYAEGPYLRSHSWFVGFAPFDNPKVAILAMLEGTGDLGDGSGTLALPAVVDVLRAYNGEAFPDINGNLPAPAAGSTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B271</accession>
    <name>A9B271_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_4790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
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            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
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            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4790"/>
    <dbReference type="EnsemblBacteria" id="ABX07421">
        <property type="protein sequence ID" value="ABX07421"/>
        <property type="gene ID" value="Haur_4790"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4790"/>
    <dbReference type="HOGENOM" id="CLU_2287635_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4848-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="101" mass="11350" checksum="2426D049B5AA28F6" modified="2008-01-15" version="1">MAMALCMIMQLDSNPANPWAVAEQFCRGYAEWITLTPQEITAMPHLIGLRTAIPVIWALSKTERPNPTNLVQAIRRMQASKAWMSHHHPQLISLLQTAFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2D7</accession>
    <name>A9B2D7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03982">
        <property type="protein sequence ID" value="ABX03982"/>
        <property type="gene ID" value="Haur_1337"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1337"/>
    <dbReference type="HOGENOM" id="CLU_2369011_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1358-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="95" mass="11294" checksum="D02BBA1B48221667" modified="2008-01-15" version="1">MGKKLNLEPIACESFGEARDKAAHIARYSQYRYLVWERGDDQYYYALATPQTVKQMMLDAGTQGLMRIYDRTGFLRLTWWVANNIRRQLLRTWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2E6</accession>
    <name>A9B2E6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03991">
        <property type="protein sequence ID" value="ABX03991"/>
        <property type="gene ID" value="Haur_1346"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1346"/>
    <dbReference type="HOGENOM" id="CLU_1710765_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1367-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="17395" checksum="DA5051E71B1BF3B0" modified="2008-01-15" version="1">MQTFDIANAGDFSDGSINAVRTAMNAAKVRKPYACIQYRYNETLTYYIPDSSESVEHLIALVDTIVVANPGIKTATVMNEQSHILWMVERNRHHGYLMEQSILRLCAGYTCWECGHCQATPFRCCLICSMDNTCQPSPLRWVHTYRDDCAAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2J4</accession>
    <name>A9B2J4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04039">
        <property type="protein sequence ID" value="ABX04039"/>
        <property type="gene ID" value="Haur_1394"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1394"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_661853_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1415-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732373" evidence="1">
        <location>
            <begin position="23"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="415" mass="46184" checksum="AB83A0C23BC21F77" modified="2008-01-15" version="1">MRRFLIALGVLALLGLPRAVSAHDMCFPSDKTPYCLPDPFSDYWELNGGLPVFGYPVTAKADELNKDTGKMHPTQWLERNRLEYHNENKGTAYEVLLGLLGKERLAQLGRNPASEPREAGAKAGCLWFEQTGHNICNIEGTVGFKTYWETHGLKINGMDKFSQSLQLFGLPLTEPKMETNSAGDRVLTQWFERARFEWHPKNGAEYKVLLGLLGKEVHDNAGSPPPATLAIVSHRTYVDSIDFRWIVGEVVNNTASNQQFVKVIANLYDAGSNLVGTETGYTILDIVKAGTKSPFSILILEPPANFDHYTLQIEARETTTAPLDTFAILSFGNRDSEIGNYRYVYGEVRNDTGVPVKFTKIAITCYTKESTVQQVGFGYTSLQNIAVGQSSAFEILLSQWSGVERCEAQVQARKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P7</accession>
    <name>A9B2P7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2860"/>
    <dbReference type="EnsemblBacteria" id="ABX05498">
        <property type="protein sequence ID" value="ABX05498"/>
        <property type="gene ID" value="Haur_2860"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2860"/>
    <dbReference type="eggNOG" id="ENOG5033BUK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183870_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2891-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="74" mass="7809" checksum="58830F84BFB1CA93" modified="2008-01-15" version="1">MSGDEIMTLVGRVAASVGWTLVSVLIFYGGARLYDLLDPIDYREEIKRGNVAAAIQLAAVTIALAAIVIMAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U0</accession>
    <name>A9B2U0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2903"/>
    <dbReference type="EnsemblBacteria" id="ABX05541">
        <property type="protein sequence ID" value="ABX05541"/>
        <property type="gene ID" value="Haur_2903"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2903"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_4_4_0"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2934-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="323" mass="36505" checksum="58802FA8218A0A51" modified="2008-01-15" version="1">MEPTANLTTIQVGEAEAGQRLDRLVSANMPDLSRTYVQQLITDLHIRVNGRGAKASLPVQIGDQIEIFLPLAKPTDIVAEDLPLDVIYEDADVLLVNKAAGMVVHPAPGHTTGTLVNALLYRYPHLTTSGDLRPGIVHRLDKETSGLLVIAKHDQARMMLTEQQMARRMHKKYLALVEGHWREPTGTIDAPIGRNPNNRLRMMVMPEGRYAVTHYQVLEVLGPYSLVRATLETGRTHQIRVHFSYRNRPILNDALYGHRKPKETFGIERHFLHAYHLGFRLPSTGEWCSWEVPLPAELEKILTTLRTRYETIVYPDPLIEAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B372</accession>
    <name>A9B372_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4905"/>
    <dbReference type="EnsemblBacteria" id="ABX07535">
        <property type="protein sequence ID" value="ABX07535"/>
        <property type="gene ID" value="Haur_4905"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4905"/>
    <dbReference type="eggNOG" id="COG3241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112845_2_0_0"/>
    <dbReference type="OMA" id="HNWVLVN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4966-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734524" evidence="2">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="3">
        <location>
            <begin position="54"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="15635" checksum="9B0FAC2030220136" modified="2008-01-15" version="1">MKKLSLALLLVVSLTLAACGGEAATTAPSTDNGAATSAPSTGGGSSTLTIDAAAGGTLAFAATAAETTAGEVTVTFNNPGALAHNLVIVKTGEEQAAVDASMASAPDFLPPADKALGHSKTIAAGASDTFTVSLQPGTYSFICTYPAHYAAGMKGTLTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3A3</accession>
    <name>A9B3A3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1422"/>
    <dbReference type="EnsemblBacteria" id="ABX04066">
        <property type="protein sequence ID" value="ABX04066"/>
        <property type="gene ID" value="Haur_1422"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1422"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1114264_0_0_0"/>
    <dbReference type="OMA" id="IIELTWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1444-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="137"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="250" mass="27073" checksum="F6FF150FFC952C3A" modified="2008-01-15" version="1">MAQTAELKLPGLLDSLGALCKFAYQAALDAGLNEHTAWEIELAVDEAATNIIQHAYSAERPGDVRLVCGRDGSRFVVRLFDRGVPFDPETVPPPDLTSSIETREAGGLGMYLMGRMMDDVQFNYNPETGENELHMSKIVGTRLPEDVRVVPVQGRIDATAAPALATIVHEAAETGGRRILLDLTGVTFLSSSGLRILLLLARELKGSNGELRLCSLQPAVAEVFTLTGFTQIFTIHRTRDEALAALADVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3G5</accession>
    <name>A9B3G5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1484"/>
    <dbReference type="EnsemblBacteria" id="ABX04128">
        <property type="protein sequence ID" value="ABX04128"/>
        <property type="gene ID" value="Haur_1484"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1484"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_1_0"/>
    <dbReference type="OMA" id="HTLAFIK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1506-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="52"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="170" mass="19896" checksum="35809C562008B6C9" modified="2008-01-15" version="1">MFGPVGRLGLVHKHNQLPLALEHTLSYIIQSVDVDICAGVECMVMQQVVEQSLTIQQMAEITGLSAHTLRYYERAGLLHDLVDRNQQNGYRSYTQRHINWIHFIKCLRATGMPIRDIRRYTELLHQGDHTVRDRLNLLKAHRLRVEQQLTEVQQHLEAVKRKISYYETLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3I7</accession>
    <name>A9B3I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2921"/>
    <dbReference type="EnsemblBacteria" id="ABX05559">
        <property type="protein sequence ID" value="ABX05559"/>
        <property type="gene ID" value="Haur_2921"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2921"/>
    <dbReference type="HOGENOM" id="CLU_2301986_0_0_0"/>
    <dbReference type="OMA" id="MSVWDFQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2952-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021857">
        <property type="entry name" value="DUF3467"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11950">
        <property type="entry name" value="DUF3467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="11040" checksum="830CC46D18513F5B" modified="2008-01-15" version="1">MSDQSPRAAYANQVQISGSPYDFTIDFACVEDVRNNTASVQPVARIMMSPQHTKVLALMLLKHVAAYEHAIGVIELPSALLNDMKLGNLEHFISQVNLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3J2</accession>
    <name>A9B3J2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="9" type="ordered locus">Haur_2926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2926"/>
    <dbReference type="EnsemblBacteria" id="ABX05564">
        <property type="protein sequence ID" value="ABX05564"/>
        <property type="gene ID" value="Haur_2926"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2926"/>
    <dbReference type="eggNOG" id="COG2262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019597_1_0_0"/>
    <dbReference type="OMA" id="AEMKTGR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="8">
        <location>
            <begin position="218"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="224"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="249"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="337"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="368"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="444" mass="49599" checksum="AB414D8924C1CBC4" modified="2008-01-15" version="1">MSNSVRERMHVTAKPKERALLVGGDIYNNREAWHIDDSLDELALLADTAGLEVVGTVSQKLDHPNPKTYIGPGKVREVADLRSETPYDVVIFDEELSPSQARNLEEAIKVKVIDRTTLILDIFAQHARTREGSLQVELAQYDYLLPRLRRAWTHLERQSGGGGGGSGVGVGLRGPGETQLESDQRIIGKRIALLKEQLADVHRHRELYRQNRQESGLPIISVVGYTNAGKSTLLNRLAQADVLAADMLFATLDPTTRKVALPGGRAVLMTDTVGFIQRLPTALVAAFRATLEEIAEADVLLHVLDLTHANVEEQFKTVIDTLSELKVQDKPILTVFNKIDKIDSPSDAEIVRMITELGLPIDRWVAISAQQNIGIDRLQTAIEQMLMERMVKFEVMIPYRANELVALWHERGMIESEEFGAEGTTLRGAVPRQFAHRFEPYRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3M2</accession>
    <name>A9B3M2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2956"/>
    <dbReference type="EnsemblBacteria" id="ABX05594">
        <property type="protein sequence ID" value="ABX05594"/>
        <property type="gene ID" value="Haur_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2956"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
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    <dbReference type="Pfam" id="PF12146">
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        <property type="match status" value="1"/>
    </dbReference>
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    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="25"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="277" mass="30431" checksum="38064FB94F409D81" modified="2008-01-15" version="1">MEHTTATFTGGNNTTIFYQTWRPAAPKATVVVVHGYAEHSGRYQHVAEALVAANYSVWALDHRGHGQSQGNRATVKHFDEFVNDLASFVRLVRDKEPNGPLFMLGHSMGGLISTLYTLDYGHNLHGLVLTGPAFKVDATTPKVVVKVGAFISKFLPNLPVAPFDPQWNSRDPKVVEAFKADPLNYKGGIKAQMGTSMINATKVIDQRAHEISLPVLLLQGLADRLVSPAGAMHAFGLFKSQDKTLHSYPGLYHEVLNEPEQTTLIPLVIEWLDAHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Y1</accession>
    <name>A9B3Y1_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3481</name>
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    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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            <taxon>Herpetosiphonales</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3481"/>
    <dbReference type="EnsemblBacteria" id="ABX06117">
        <property type="protein sequence ID" value="ABX06117"/>
        <property type="gene ID" value="Haur_3481"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3481"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120515_0_0_0"/>
    <dbReference type="OMA" id="KSHEDLG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3518-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="143" mass="15830" checksum="9E4371990A67F83B" modified="2008-01-15" version="1">MSNPLLDQTNLVVQLCITGTQAEMHDRIGAAQAAYQQAWAVAQTALDRCIAAHYCARHQPLATMLEWNQIALEEAKLVESSAISEFLPSLYLNLAWSYEQNAQLDQALEQYQACLTSLAALAEGSYRTMINDSALAALQRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3Z4</accession>
    <name>A9B3Z4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 6">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3494"/>
    <dbReference type="EnsemblBacteria" id="ABX06130">
        <property type="protein sequence ID" value="ABX06130"/>
        <property type="gene ID" value="Haur_3494"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3494"/>
    <dbReference type="eggNOG" id="COG0334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025763_1_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3531-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
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    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="7">
        <location>
            <begin position="181"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="416" mass="45246" checksum="4E738BD2A2D737A0" modified="2008-01-15" version="1">MIETTMATAQRQFDIAAELLALEPEVRDMLREPRRELIVHFPVKLDNGRVRTLTGYRVHHNITRGPALGGLRLQSSATLDEMQALAMWMTWSCAIVQIPYGGAKGAIVCDHRELTSGELERIIRRYVTEITPLIGAERDVIMPDLNTNEQTMAWIMDTYSMHHGYTMPSVATGKPVQVGGSQGHGQGTARGLCYTVRQAASKIGLDLAGARVVMQGSGSTGRLVLQFLAEMGCRIIAASDDTTGIVAESEAGIDVAALIEHRVQTDGVANLAGTKPISHNELLELPCDILVLAAGQNDISGANAGRIQAKIVVELANGPITPTGDSILANKQIMVVPDILANAGGIVVSYFEWVQGLQEFFWTEREVHGELATTMERAFNEVFTVAQERFVPLRTAAYLLAVDRVVRAMAMRGIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B439</accession>
    <name>A9B439_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ordered locus">Haur_4942</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4942"/>
    <dbReference type="EnsemblBacteria" id="ABX07572">
        <property type="protein sequence ID" value="ABX07572"/>
        <property type="gene ID" value="Haur_4942"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4942"/>
    <dbReference type="eggNOG" id="COG0101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_0_1_0"/>
    <dbReference type="OMA" id="FLYGMVR"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="8"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="145"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="29838" checksum="F639821D0A5BD158" modified="2008-01-15" version="1">MSRTLALCFEYLGTAFCGSQWQPGGRAVQTELETAWQRLTSETGRWIFAGRTDAGVHALAQVAHIVSDTPRSLDTIAKAINAITPPDISVHEAWEMPTGFHARFSARQRTYRYVFDSAPAPSATLSGRVLRLDHQLDWAAMQAALDTLIGTHDFAAFAGAGHEGSTTRTCMLAQLRPAEWLGRPVTVLHLQANAFLKHMVRNIVGTLLMVGDGRLSLEAWQAIIASRDRRNAGPTAPPQGLYLESIGYDPALQPLATSSRWDGTTYFRTYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-06-02" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B482</accession>
    <name>A9B482_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoH</name>
        <name evidence="7" type="ordered locus">Haur_4985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4985"/>
    <dbReference type="EnsemblBacteria" id="ABX07615">
        <property type="protein sequence ID" value="ABX07615"/>
        <property type="gene ID" value="Haur_4985"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4985"/>
    <dbReference type="eggNOG" id="COG1005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_1_0"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="413" mass="45005" checksum="476912CC43A7A0AB" modified="2008-01-15" version="1">MADALTQLGFASWLSVLIASIIKVTLILVGGSVGMMFLTWYERRAISYMQDRRGPNRVGPQGLLQPISEAIKTMTKEDATPREADRIVHFLAPVVMLGATVLSFAVIPWGRMFPVDLNAAVLFVIATGGLHSIGMMMAGWGSNNKFALLGGMRGVAQLISYEIPQVMAIIPVVLMTGSMSLQKIVEAQNDFGGLGWFVFSPVGLLGFALFFTASLAEGERTPFDIPEADSEIIAGYMTEYSGMKFAVFYLSNYMSNLAVCFITATLYLGGGNGPGVDALGGFAGGLLSLIYFLLKSFALFFIMVLIRATVPRLRVDQLMGFAWKFLLPLVLVNILSASFWVALLRWDQQWPQLTEWFGAPSTADATNWGRLAIAVVLTLLINAGAVALIMRLTNRNVQKHLYTTDEELALGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B485</accession>
    <name>A9B485_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
            <ecNumber evidence="10">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4988"/>
    <dbReference type="EnsemblBacteria" id="ABX07618">
        <property type="protein sequence ID" value="ABX07618"/>
        <property type="gene ID" value="Haur_4988"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4988"/>
    <dbReference type="eggNOG" id="COG1009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_6_1_0"/>
    <dbReference type="OMA" id="ILASAWY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5051-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="546"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="717"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="102"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="174"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="736" mass="80079" checksum="5506763A370A0188" modified="2008-01-15" version="1">MPFFDLAWLIPLLPLAAFVLITLVPPIGRSRKASYTTALVLLGLATVIAWGVLAQSISEGFPNAPLVAAASQESASEATAEGGHAETAIPTFGNFYAKSFAWAPDGSGFFKFGYRLDGATVLMLAMVTLAAWCIHLFSVGYMAHDEFPTGHQRQSRFFSYIALFTASMLGMTLADNLLLFFICWELMGLCSFLLIGFWFFKPSAREAAKKAFITTRIGDVGMMLGMMYIYNKAGSLTFGHEPGQIYNGEFLESIKTATSLIPGISAASLMAGLVFLGTVGKSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVFLVIRTFPIFAVSEVLPVVAFIGAFTALFAALIAVAQYDIKRILAFSTLSQLGFMVAALGIGAWVAALFHLLTHAFFKALLFLGSGSVIHGMEATVGHDPDKAQDIRNMGTLRKFMPITFLTYMAGFFALIGIPPFAGFWSKDEIILDAFLHHHYVVYGVLTAAAFLTAFYMTRQIVVVFFGKFRGYEPRKLAHAAAHGHDDHGHGDHDDHHHHHEAHDPHESPRSMTIPLIILSLFAVFAGFVNAGFLGIHWFADYVNPGGLIPKPDFMVAGIATAVALVGAGLGYLTYRNAFKNANDRDPLAGALGPIWTLLENRFYIDQIYDKTFIALTYGAGQVMNWIDRHVVDRVVNLTGLLTLFIGRINFIIDDFSLNTVTDDIGEGTIMVGDGVRQSATGKIQDYGAYIFGGVVLLALIYMYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D2</accession>
    <name>A9B4D2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0037</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0037"/>
    <dbReference type="EnsemblBacteria" id="ABX02689">
        <property type="protein sequence ID" value="ABX02689"/>
        <property type="gene ID" value="Haur_0037"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0037"/>
    <dbReference type="eggNOG" id="COG0674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017038_1_0_0"/>
    <dbReference type="OMA" id="GMPTRTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-37-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="34"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="236"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="611" mass="67031" checksum="04B5B2DAAF3F34D5" modified="2008-01-15" version="1">MAVVDYQTEQQPAEIAREDVNINDFAIIVATPNGSGSQTANNTILRACFNMGIPVTGKNLFPSNIKGLPTWYSIRLSKDGYQARRHKRDVLVAMNPASFGDDLQSLEPGGICLYPDDSRQELSRSDVTYFPMPVKELVKNSGVDASLRDYIANMVYVGVLAHLVGIEVAEIESALNKHFKGKQKAIASNMNVVNAAVAWAAANISTPSPFRVERMDKTKGMIMLDGNTSGALGSVFGGVSFVAWYPITPSTSLVDALNDYLPELRIDKETGKPTYAVVQAEDELAAIGMIIGAGWAGARSMTATSGPGISLMAEFTGLAYFTEVPCVVWDVMRMGPSTGMPTRTGQGDLLSAYFLSHGDTQHVCLLPASVKECFEFGWRSFDLAERLQTIVFVLSDLDLGMNQWMSEPFEYPTEPMDRGKVLDAEALTAVGDWGRYRDVDGDGIPFRTLPGTNHPKAAFFTRGSGHNQDAKYTERSDEWVANMDRLARKFETARTIVPAPIMVNEENATIGILSYGSNDPAIIEALDRLRELNINAAYQRVRALPFTKEVGEFVAKYERIYVVDNNYNGQMAQLLRMEYPELAGRIIAVASCDGLPLTARWVTESVQKGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q6</accession>
    <name>A9B4Q6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1578"/>
    <dbReference type="EnsemblBacteria" id="ABX04221">
        <property type="protein sequence ID" value="ABX04221"/>
        <property type="gene ID" value="Haur_1578"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1578"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_1_0"/>
    <dbReference type="OMA" id="MSWIFAS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1602-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="274" mass="30238" checksum="C61B5BC099803048" modified="2008-01-15" version="1">MLQDYGRMAYVAEYPQTTVRRKQRRAWLGSSRLWVGLSLLGLLLAWRGLVAWQQYPAFVLPTPEAVASRWWQELTQGALLQHTSRTLIEALGGFGLAFSASLVLGYILAHWHWLDRIVSPQLAIVQAIPIVAVAPLILIWVGADLRAKLLVAALVTFFPMLSSVIVALRSVPRDIREMAAISGANRWQSLWQIELPLALPGIFGGIKTGLALATTGAVVAEFIGGREGLGALINIARGLFDTPLIFAALLTLGLLTFGFYQLAMWLERRLVTWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q9</accession>
    <name>A9B4Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1581"/>
    <dbReference type="EnsemblBacteria" id="ABX04224">
        <property type="protein sequence ID" value="ABX04224"/>
        <property type="gene ID" value="Haur_1581"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1581"/>
    <dbReference type="eggNOG" id="ENOG5033MKI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1966628_0_0_0"/>
    <dbReference type="OMA" id="IDQANEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1605-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="15277" checksum="106EFB6CEF718ED5" modified="2008-01-15" version="1">MAEHPAPIDVGAILAEIRDGIRQRRANGLIDQANEPQLSDVDLKRLLAEVEATRVVSVHWPLHGETLPQKVIATLNKVVRRYLRWYINPIAEQQNAANDAIVRTLHGLVTTIDEQRAEIALLRARVVELERERQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4X6</accession>
    <name>A9B4X6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3061</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3061"/>
    <dbReference type="EnsemblBacteria" id="ABX05699">
        <property type="protein sequence ID" value="ABX05699"/>
        <property type="gene ID" value="Haur_3061"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3061"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="IMITARV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3093-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="227" mass="25175" checksum="31F80CC2846DBCF8" modified="2008-01-15" version="1">MSAKILIVEDERKIAVGLQNYLEGVGYSTITASDGQAGLDMARREQPDLVLLDLMLPMVDGFTVCRTLRAESSVPIIMLTARVEEVDSLAGLELGADDYITKPFSPRQVVARIKAVLRRVNGELEPPMIVRKSGIEIDLQRRTVVIEQNPITSLTPTEFDLLVTLVRSAGRPLTRSQLLDAVQGEEGEAYDRTVDAHIKNVRRKIEPNPSVPRYILTVFGVGYKFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B530</accession>
    <name>A9B530_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3531"/>
    <dbReference type="EnsemblBacteria" id="ABX06167">
        <property type="protein sequence ID" value="ABX06167"/>
        <property type="gene ID" value="Haur_3531"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3531"/>
    <dbReference type="HOGENOM" id="CLU_1452587_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3568-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735456" evidence="1">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="21711" checksum="A8A309A6239C715D" modified="2008-01-15" version="1">MKKYKYLLLIILFLISCTNKENIVDNNELKIYIFTNEDINSQKAANPHISDTLNLLSTIDLEHAAYIIHESDIIAYDWREQTIKIINSWHNRPQETPFFMHEGSKVIVVFQQQRIILTSLLSEDTARFIPSDETAMYSSFRQNHIFYSFRYGSLLQTAQSYPFLNPDPAIAEAVKQHLRQLGKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B532</accession>
    <name>A9B532_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3533"/>
    <dbReference type="EnsemblBacteria" id="ABX06169">
        <property type="protein sequence ID" value="ABX06169"/>
        <property type="gene ID" value="Haur_3533"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3533"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2865">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024970_3_3_0"/>
    <dbReference type="OMA" id="EREDWTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3570-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025831">
        <property type="entry name" value="RecG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038475">
        <property type="entry name" value="RecG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13749">
        <property type="entry name" value="HATPase_c_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AlbA_2" evidence="3">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c_4" evidence="5">
        <location>
            <begin position="290"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="459" mass="51487" checksum="B554C6C77EF09915" modified="2008-01-15" version="1">MLEQLLENGESEMLACFRERFRPEDLAETLVAFANGGGGSVVIGISGRVRPKVEGVQDIQAAEEAALEAALACTPPLVLPLPQQITSNQQTVLLIEVPPGLPNVYSLHGKYLRREGPSNAPIPPNALRQLLIERGEVGWERVRPENVTMGDLSEMKIQSYVARIGPPADVDPMGWLYRRGCLVRDAQTNYQPTNAGMLLFSITTERDYPQCELTLVRYTGNEMSDEFERVDIRTTLPDQVRRAELWLGEHMRRGSRMVGLEREDWTEYPPAAVREALVNAVAHRDYTVRGEGIRIAMFVDRLEVYSPGRLPGHVTIDNIAAERFSRNETLVQVLADLGLIERLGYGIDRMQRQMADAGLPPPEFRETAAGFLVTLRNKGMNVASNSTIDTAKWEALGLNERQIGALVYLTENRRITNRDLQDLSPDVSPETIRRDLSDLVDRGLILKIGQKRATYYILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5B6</accession>
    <name>A9B5B6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IstB domain protein ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0089"/>
    <dbReference type="EnsemblBacteria" id="ABX02741">
        <property type="protein sequence ID" value="ABX02741"/>
        <property type="gene ID" value="Haur_0089"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0089"/>
    <dbReference type="eggNOG" id="COG1484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062999_3_2_0"/>
    <dbReference type="OMA" id="GSPFEME"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-90-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="118"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="266" mass="30238" checksum="F986A437F4350A9F" modified="2008-01-15" version="1">MEKNLRRIDPSSFSISANIPRANMPPSSEEAAIPMEETCPICKGAGYFCMDVPINDPNFGHLITCQCKLAEKEGRQRDKLWQQSNLQAFETKNFDTFNSHIVGVNESFARAKAFAQAPKGWLLLVGGYGCGKTHLAAAIANEAVRREYQTIFMVVPDLLDYLRSTFGPNSEVAYDERFDKIRSIQLLVLDDLGAESSTAWAREKLFQIINHRYNNHLPTVFTTNVDLDKLDPRIASRLLDVELCRQTVIQAKDYRQTTRNNNIRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5N9</accession>
    <name>A9B5N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1629"/>
    <dbReference type="EnsemblBacteria" id="ABX04272">
        <property type="protein sequence ID" value="ABX04272"/>
        <property type="gene ID" value="Haur_1629"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1629"/>
    <dbReference type="eggNOG" id="COG1598">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114047_2_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1653-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="69" mass="7699" checksum="A2063B58BD372126" modified="2008-01-15" version="1">MRYAIVIEQGPNNCSGYILDVLGCVATGETPEEVKQRLQEAIVMHLEGEPIPPSTTLVDYIEFEPEINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5T7</accession>
    <name>A9B5T7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1677"/>
    <dbReference type="EnsemblBacteria" id="ABX04320">
        <property type="protein sequence ID" value="ABX04320"/>
        <property type="gene ID" value="Haur_1677"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1677"/>
    <dbReference type="HOGENOM" id="CLU_294369_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1701-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1030" mass="120363" checksum="A8335BBAE28D8220" modified="2008-01-15" version="1">MQTCLPSSWIERIKQLLGYTNHQPPTIPWLLVPIGDAELTDAEINQLFMTLRQYLLPSRLQSPLTQIRARLARFTHEDRLVFLYALRLVALRGGGLNRYWTLCCEQLFDSQIDLDNLRTNIAPEITSQWIRFYRETNAALFVPQHGKKNIKWPLAHAGLLVQDKRLLESFWRTMRLTWTSDEFQLLTHSDNIDDLELDLKKWLIDHQFTTTHLYQSIHNSEHSSITLDLIQYYLKELNQQSLNTNQVLSKNQINSIQMRCFRRFFYNHSQNQIELHCTLYFNQPQGKLWSDWDKKLVYWVFDDTFYKYTLNLPINSLNTLISIHVNGINYNTQIDLPIISNDEPVIFNEISGQRLRTWQLGERYLIALPSKSAADPNLQKLFSEYEAAIRPKGLWHDFVFKWVTVRLPSDDCSFIDLNEYATDYDFPVFEAYGTPTVSLLGGLEIGLINDIHYFHADQPPLIKIAGCWNKPLQIQLKKQLINDPSAQNVLQIYLPPQSELSDHFLEPELDSDSEIVFMLSIDGQLKLQWAYTYPEYQSTYYVLKSAVNIVFQDKVQPALTSAILKQSRLQIQAWPHAQLQIVAKSSLDSVTIPLSLDASGFVDLPLAVTQIMNLQRTSFIFWVAWRNIPISPIFDCYQPRMLDPDSIVTYLTEDRLEILMDLPQYQKSINLFAIVLGEYPWENQIWQQIKRIETGSVQFNLRLNPQVVRWLALFEADGQKPGSFLGFYELQKSQPSPAKTPKMTRQWQHFIQLMNQQVLPKRLGKLVLDTQTLDRWATLRQYLLDTNHWIELRRPTIIDTIIMLRAQAVFIPLVLTEHLPHIHTFNQNAHILYPYDINAFQRTMLITTNKIRVYGKIAHNEIYETDITTHWNIIDGEYKLFIDDHSQHTIYACRNCRLILMSKIAHQHLMQAGYTCHEKDIEQLRYPRVYLCALIGVEVIFRQFIKIIDDFIDNKPVGQFWESLFDELSLLMPQDKDIDPLTWLKGLQEIGMVVLAEAAQPTLPSTCQRLFLAYARALELVLTRIKELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5X3</accession>
    <name>A9B5X3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3129</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3129"/>
    <dbReference type="ESTHER" id="hera2-a9b5x3">
        <property type="family name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05766">
        <property type="protein sequence ID" value="ABX05766"/>
        <property type="gene ID" value="Haur_3129"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3129"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_13_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3161-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1371"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1436"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1464"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1496"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1525"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1580"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1614"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1642"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1665"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1707"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1755"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1013"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="10">
        <location>
            <begin position="1371"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1816" mass="200884" checksum="9685027463885CFB" modified="2008-01-15" version="1">MTEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLSQWQPESAAYHIPATFSIAGEINVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRSLDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLMLRGLLLHTAADHAELVLTIHHIACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFWQEQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAAFQVLLYRYSGQSDLIIGTPIANRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQTSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQTTSIQTVDSGEFGLQFGGAIETGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLSSSERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQLAHSLRQRGIGCDMRVGLFIDRSLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAVSLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNLALEPRSLMYVLFTSGSTGRPKGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYERATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDIRQLQPSVQLQNHYGPTETTVSMLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGARLYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNIGSIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEHELAGIWAEVLGLDQVGIDDNFFDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHLSGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQPLAQAMPKGYRLLAAELPGHDFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGIVLGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSLRHDAREVERYFTQAFAQKQSQQLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVIPHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSKSHKTSMPSLRIFFMVALGQLVSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMIIADTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHANGVIQLGSATGGLIAPFIAGGMVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKREEPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASISMSPLVLSFGGPAELGIVSAACALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAISLVNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALSSSLGWLFGVGPDRGIGLLMVVVGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRDTIQAQADGIIAVTAKG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5Y6</accession>
    <name>KCY_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidylate kinase</fullName>
            <shortName evidence="1">CK</shortName>
            <ecNumber evidence="1">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine monophosphate kinase</fullName>
            <shortName evidence="1">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmk</name>
        <name type="ordered locus">Haur_3142</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B5Y6"/>
    <dbReference type="SMR" id="A9B5Y6"/>
    <dbReference type="STRING" id="316274.Haur_3142"/>
    <dbReference type="EnsemblBacteria" id="ABX05779">
        <property type="protein sequence ID" value="ABX05779"/>
        <property type="gene ID" value="Haur_3142"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3142"/>
    <dbReference type="eggNOG" id="COG0283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079959_0_2_0"/>
    <dbReference type="OMA" id="RAITWWM"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000125288" description="Cytidylate kinase">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="15"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <sequence length="229" mass="24745" checksum="88F7FFF8B7C49491" modified="2008-01-15" version="1">MFFTMTTPHTIAIDGPAASGKSTLGKLLADHFGYIYFDTGVLYRALTYVALEQAVDLADAAALAKLAQTSNFEVLPPTIADGRQYTVLANGEDITWPLRAANVERNVSQVAAQSAVREALRDIQRQIGKAGHVVMAGRDIGAVILPDAQLKIYLDASVEERAQRRAQELNARGRSISYREVLDDLTRRDAKDAANTFLAADAITITTDGRSPEEVFQAILGLIGVEAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B601</accession>
    <name>A9B601_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3157"/>
    <dbReference type="EnsemblBacteria" id="ABX05794">
        <property type="protein sequence ID" value="ABX05794"/>
        <property type="gene ID" value="Haur_3157"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3157"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3189-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="275" mass="28608" checksum="1B0FFB3CDE2E97E7" modified="2008-01-15" version="1">MALLAEKVALITGAGRGIGAAAARLFSQHGARVVLCDLDAAPVEQLAAELKAAGGQALAFAGDVTSAEFAPQAIAATLEHFGGLDVLVNNAGYTWDGVLHTMDDAQWQAMLDVHLSAPFRLIRAAAPYLRDTAKAEIKAHGAAKARKIINVSSVSGVYGNAGQVNYSAAKSGVIGLTKTLAKEWGRFNVQTNAVCYGFIETRLTAAKEQGETIQRGDQAIKLGVPENLMAGITMFHPMGRAGTPEEAAGPMVFLASSLANYVNGEILEVTGGMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B605</accession>
    <name>A9B605_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3161"/>
    <dbReference type="EnsemblBacteria" id="ABX05798">
        <property type="protein sequence ID" value="ABX05798"/>
        <property type="gene ID" value="Haur_3161"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3161"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_0"/>
    <dbReference type="OMA" id="AREIFME"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3193-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="195" mass="21812" checksum="A42BCD21EECDD288" modified="2008-01-15" version="1">MARTADPHRREAILRAAREIFMEQGYTKARMLDIAARAEMATGTLYLYFDSKQTLAMALADSVLEGLTEVILPILALESTPTMIRACVQTAIRFSLQHTDLFRLLGLEAGLSIEVEHQQPARLRLHALLAEALAQRMQQGTIYTYQPLALAEILAGLIEWVVTMAMIRGESDVSHYEPTLLQFIEQALLPPNPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B688</accession>
    <name>A9B688_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3663"/>
    <dbReference type="EnsemblBacteria" id="ABX06299">
        <property type="protein sequence ID" value="ABX06299"/>
        <property type="gene ID" value="Haur_3663"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3663"/>
    <dbReference type="eggNOG" id="COG0235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_3_0_0"/>
    <dbReference type="OMA" id="AHERYMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3702-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="23131" checksum="1299E95E57D28919" modified="2008-01-15" version="1">MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVDLNGNVIEGDLKPSSDTASHLYIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADEFGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVFTIGKSAKAAVKAAVMTEDVARTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6A5</accession>
    <name>A9B6A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dihydrodipicolinate reductase</fullName>
            <ecNumber evidence="10">1.17.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3680</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapB family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3680"/>
    <dbReference type="EnsemblBacteria" id="ABX06316">
        <property type="protein sequence ID" value="ABX06316"/>
        <property type="gene ID" value="Haur_3680"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3680"/>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_0_1_0"/>
    <dbReference type="OMA" id="HHPNKAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3719-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="9">
        <location>
            <begin position="130"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="267" mass="28243" checksum="23F2EA476F0E85AE" modified="2008-01-15" version="1">MSIRVCLAGATGWAGSALAQGIAKTNDLRLVAAVSRSHAGQQVGVVLNQPELDCPIFATAEEALSQPCDVFVEYTKPAVALDNVLKALASGAHVVIGTSGLDDPAYATINEAALKAQRGVLAVGNFALTVVLLQKFATIAARYIPHSEIIDYASDKKIDAPSGTARELAYRLGQVRDSAQTVPTEAIVGEQATRGARMAEQQVHSVRLPGYVISIEAIFGMPDQKLILRHEAGNGAEPYVDGALLAIRNVHTFVGLKRGLEHVLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D1</accession>
    <name>A9B6D1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0182"/>
    <dbReference type="EnsemblBacteria" id="ABX02834">
        <property type="protein sequence ID" value="ABX02834"/>
        <property type="gene ID" value="Haur_0182"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0182"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1223353_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-185-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="226" mass="25060" checksum="071CF21E52734355" modified="2008-01-15" version="1">MSSVHETHLLAEGITAAKAGQRAAARDFLTQVIALNARNELAWLWMSAIVDTPEQRRDCLVRVLLINPSNEAAQRGIAALEVQNKPAPSMPEPTPIVAIAAASSNLIQCPFCQANTDSSKLDCQVCGENIILTCPSCDSTINLWETTRCPCGEGLRHYIFFPDGIDHEGLGQRYALMERWEPAARQWDRALKDGSHVVMLHRKLAQAYDKIGRNQEAEFHRQVAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6M5</accession>
    <name>A9B6M5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobalamin (Vitamin B12) biosynthesis CbiX protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1691"/>
    <dbReference type="EnsemblBacteria" id="ABX04334">
        <property type="protein sequence ID" value="ABX04334"/>
        <property type="gene ID" value="Haur_1691"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1691"/>
    <dbReference type="eggNOG" id="COG2138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1501530_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1715-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="179" mass="19915" checksum="C141AC3358006C2A" modified="2008-01-15" version="1">MTEQQPMAAAPIKYREDGEVDWANMWETFCDLALEGGPAHRGAEANIPIQINANPQHPNYMQVYAELCRGIYEVSGLSAHIGEKPEWLAIECPIVGQAQWLAGAINQEHVAAQATGQQLLVPIHQDFSLKSEIKSVITVVAKTTHYWTEHLPQSVKQSFAIQAQLSKAGKKIKRLFNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6S9</accession>
    <name>A9B6S9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="3">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1745"/>
    <dbReference type="EnsemblBacteria" id="ABX04388">
        <property type="protein sequence ID" value="ABX04388"/>
        <property type="gene ID" value="Haur_1745"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1745"/>
    <dbReference type="eggNOG" id="COG1648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_8_1_0"/>
    <dbReference type="OMA" id="VYMPKIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1772-MON"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042518">
        <property type="entry name" value="SirC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="PTHR35330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="21789" checksum="B3CB9D50EC0337D4" modified="2008-01-15" version="1">MYPIVLTNLAQQRCVVVGGGAVAERKVAGLITGGANPIVISPQLTPQLQHWQASNQIQHLAREYQFGDCEAAFLVVAATNQRLVNQQIAHECHNRPILLNIADAAEEGNFITTANHRQGSLLFSVSSSGASPALSRYLRQQLSNYFDQRYATLAQIVAAQRAELATLTTTEREQYFDQLLVELAQQPPTLNHLPTEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B755</accession>
    <name>A9B755_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3702"/>
    <dbReference type="EnsemblBacteria" id="ABX06338">
        <property type="protein sequence ID" value="ABX06338"/>
        <property type="gene ID" value="Haur_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3702"/>
    <dbReference type="eggNOG" id="COG1364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1080828_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3744-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="26769" checksum="F317BB1956440910" modified="2008-01-15" version="1">MAYRLLNEGSITTPTGFRVTGIHCGLKTTSRDRDLGLLITKTGCTVTGHFGATSGITGAWTTANLRRNAEDVRAVLLLTGVDGGRGASAVHNCQELAGLLAEEAWIKPEQVVLLAAGAAGPFDMDLLRRGVPRALDELDSKGGRRLALALAQEPNPTAQAAVEVEASDGTSASIGGLASSGDAPRWLITTNAQLSTRLLNRAVLALLEAYPALDQAAILILANPSASLAPTHSNQAAYREWYAGLAGLIAHLSEQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B761</accession>
    <name>A9B761_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ctaB</name>
        <name evidence="9" type="ordered locus">Haur_3708</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3708"/>
    <dbReference type="EnsemblBacteria" id="ABX06344">
        <property type="protein sequence ID" value="ABX06344"/>
        <property type="gene ID" value="Haur_3708"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3708"/>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029631_3_2_0"/>
    <dbReference type="OMA" id="QFFWQFP"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="443" mass="48811" checksum="5AAD502BEEA85188" modified="2008-01-15" version="1">MPALATPEQQNEVSAAISERLPAKPRDSFRPTAALTAVFSALTTINSLWWVLSPQHTLAPVLFAWLLLTALLGLVSLVGSSRAAHRPIQWLTWLAQPLGIAVIALVNTTYADWVGWANLACSVATTIITGLVAYMAYHSDISTPKAQANSKLADFRVLMKFRIISLLLLTTLIPMYLANGGEWPKFYIVVLTLLGGTLAAGGANAINMFYDRDIDAVMSRTKKRPLPNNRLTQWEVLGFGLTLSVLSFLVLLPVNLLTAILAVSGIFYYVVIYTMWLKRTTVQNIVIGGAAGAIPPMVGWAAGTDINLFVDSPIKWLPAVFLFAIVFYWTPPHFWALAIIRREDYAKAGVPMLPVVKGEAETRRQIVLYTFIMIALSFMLVSLQVVGLLYLGLAMVLGAIFLYYAANMMRDHSHAAAWKLYRYSLLYLALLFVAMGIDRALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E6</accession>
    <name>A9B7E6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmC</name>
        <name evidence="9" type="ordered locus">Haur_0267</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0267"/>
    <dbReference type="EnsemblBacteria" id="ABX02919">
        <property type="protein sequence ID" value="ABX02919"/>
        <property type="gene ID" value="Haur_0267"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0267"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_3_1_0"/>
    <dbReference type="OMA" id="FDARYWE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="123"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="189"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX02919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="30682" checksum="D198E4D7CF5249D2" modified="2008-01-15" version="1">MAITTVREALIEAASSLISASLTPQLDARVLLGHVLGLTQTQILAAFNDQLSTEQVEQFQGLIERRSALEPIAYLIGSREFYGLMFNVDRRVLVPRPDTEILVEQALTWIKQQQRPLVVADIGTGSGCIAVAVTKHAPTIKMYAVDLSPAALAVAQSNVERHGLQQQIELIHGDGVSQLPEPIDLLLSNPPYTLLDEIEPGVRLHEPTLALDGGPDGLDCYRQLLPATAAILRQGLPSAALFEIGAWQGSEVIALAQASFPQAKIQLVRDLAARDRVVQIEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q0</accession>
    <name>A9B7Q0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1785"/>
    <dbReference type="EnsemblBacteria" id="ABX04428">
        <property type="protein sequence ID" value="ABX04428"/>
        <property type="gene ID" value="Haur_1785"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1785"/>
    <dbReference type="eggNOG" id="ENOG502ZQ8Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025053_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1813-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="693" mass="78512" checksum="FAE5C0DA4B610EEB" modified="2008-01-15" version="1">MQRLTGKTIALLQRLAHFYAPAEAGELLLLFAEMFGRRLERAELDLYHVLRSHHVETATNQGSQGYIAPIEQRGDLDKIFALYLEALGGTSQLIKMNPRFTQRSFDAYRLSQIILTEQSPLPAYLDQLIDPTTWKLLRRYTVDYAYVLGSEVQAGLVLELLVQRTPISAIIAQQIAERSPQEYQQIQRYNGASSISRELALAVARALNQAILADTQFFTRHYAVLSNLSLPAHAWSLIYSLYREFLRPIYEQEPNPDRRSQLLNVLDQSESSPNPLSDDVARLNRMIVDAALGYDARLRPWGLSVRRISSLQEVRQALMMLLNQLLDDPHLVNAERFPDLAEDLPILQTTYADDLIRLNRYALETTWDYALEPSHAPYRERLQGLIAVLKRGASTRQGILDIVAANLGIVGNDPAVAAAKALIDIEEFLPKRALFFADNLKFYQEFEVDNINRSPETPHIWITMLNGPFRELTNIELIDIKSGQRVRFPGRLQIGDRLTLEGKQVLRNGIVPPEGLIGTIPQLKPGVARWRLNADIIGADGKVYPAGAFDKQAFDQTLFVPDEPIVRVEVSSYALTYGVFTVTIPWHIAGFTDKFDEGGDHPRQQILNLVNRVKAAGVQALVAYKQVFQEDHDQLDRLDLRMQGRLLNQQHDVSDSFDLESQQRSNEQHDVSDSLVLAGQFDYTRFDSLNTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Z1</accession>
    <name>A9B7Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Disulphide bond formation protein DsbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DsbB family. BdbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3287"/>
    <dbReference type="EnsemblBacteria" id="ABX05924">
        <property type="protein sequence ID" value="ABX05924"/>
        <property type="gene ID" value="Haur_3287"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3287"/>
    <dbReference type="eggNOG" id="COG1495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128688_0_0_0"/>
    <dbReference type="OMA" id="INWFGFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3324-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00287">
        <property type="entry name" value="BdbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012187">
        <property type="entry name" value="Disulphide_bond_form_BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43469">
        <property type="entry name" value="PTHR43469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18294" checksum="FA1D6CC6D63A650F" modified="2008-01-15" version="1">MQPSAIESSALSEPDEHITISFGQRVRENLGYLAWLQAVVATLGSLYFSEIKGFPPCNLCWYQRILMYPLVLILTVGIIRRDPAMRWYGLPLSIGGWLVASYHCLLTYGVISAELAPCSAGVSCLARWINWYGFITIPLLAWVAFSVITVALLFAKPAKELDHE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B890</accession>
    <name>PDXT_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="1">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="1">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pdxT</name>
        <name type="ordered locus">Haur_3807</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="1"/>
    <dbReference type="EC" id="3.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B890"/>
    <dbReference type="SMR" id="A9B890"/>
    <dbReference type="STRING" id="316274.Haur_3807"/>
    <dbReference type="MEROPS" id="C26.A32"/>
    <dbReference type="EnsemblBacteria" id="ABX06443">
        <property type="protein sequence ID" value="ABX06443"/>
        <property type="gene ID" value="Haur_3807"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3807"/>
    <dbReference type="eggNOG" id="COG0311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069674_2_0_0"/>
    <dbReference type="OMA" id="VFIRAPI"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000185891" description="Pyridoxal 5'-phosphate synthase subunit PdxT">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <sequence length="190" mass="20529" checksum="C303B165B405223B" modified="2008-01-15" version="1">MTVGVLALQGAFIEHETMLQGLGVATLQVRLPEQLVQVERLIIPGGESTTIGKLLVRFDLLEPIQQRAAEGMPIWGTCAGMILLAKEIAEGRVEGQPALGLMDITARRNAFGRQVDSFETNLQVPVLGEAPFHAVFIRAPQIDKVGEAVETLASLDDGRIVAARQGKLLATAFHPELTGDARFHELFLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8H9</accession>
    <name>A9B8H9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxylesterase NA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07643">
        <property type="protein sequence ID" value="ABX07643"/>
        <property type="gene ID" value="Haur_5013"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5013"/>
    <dbReference type="HOGENOM" id="CLU_020336_27_3_0"/>
    <dbReference type="OMA" id="SSTMWYP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5076-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="58"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="315" mass="35089" checksum="79D0A473B1E6A65C" modified="2008-01-15" version="1">MSVPPYHPFRSAAAQAVYYAHDAQASQRWPVPTETTMVETTYGQTFVRISGPVDAPPLVLLPGAGSCSRMWTFTIAPLAQHYRTYALDSLIHTGCLGRSIPTRAIATATDATSWLDQLIDGLRLTTGIHLLGASFGGWLASQYALQFQQRLATMALIAPAGTIMPFQKTYLQRTILTSLIPFRWMQQRFFRWCCADLARQAPAVLEAMVDEAMLCKRCFVPPHYKHLPTLTAMTDHELQHLTIPIAVFVGENEVLYSAHAALRRLRQVAPQIHAEIIPHAGHDLLLAQKAIVNQKLVTFFRTALGRAVQETTTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K5</accession>
    <name>A9B8K5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07669">
        <property type="protein sequence ID" value="ABX07669"/>
        <property type="gene ID" value="Haur_5039"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5039"/>
    <dbReference type="HOGENOM" id="CLU_117165_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5102-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="135" mass="14904" checksum="DC626038F32F7B96" modified="2008-01-15" version="1">MASKKPTPDQSTHDPEVRPKAARTHWSARDRLRILAAADACAPGELGALRREGIYSSHLARWRRQRAEGELAALTPKRKAAPTPEAQRQTAELARLRRENQRLQAKLAQAEVIIDVQKKLATLLGITLPAPPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Z3</accession>
    <name>A9B8Z3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XisH protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07807">
        <property type="protein sequence ID" value="ABX07807"/>
        <property type="gene ID" value="Haur_5180"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5180"/>
    <dbReference type="HOGENOM" id="CLU_132053_0_0_0"/>
    <dbReference type="OMA" id="YVIQYRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5242-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014919">
        <property type="entry name" value="XisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08814">
        <property type="entry name" value="XisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="16628" checksum="BE88FDA9192051DF" modified="2008-01-15" version="1">MQDRIHRHGCSRSLSHLGALCLRNPWLDGDPYVLTVGGVDFAIDLGAEHLMAAKRDDVQIAVEIKSFLGPSLITDFHAALGQFLNYQLALEQTDPTRQLYLAVPLDAYLTFFQLPFAQTARDLYAVRLLIYDPAQPEVLTWTPHPPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B906</accession>
    <name>A9B906_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetylmuramoyl-L-alanine amidase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_5193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4 5">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4 5">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07820">
        <property type="protein sequence ID" value="ABX07820"/>
        <property type="gene ID" value="Haur_5193"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5193"/>
    <dbReference type="HOGENOM" id="CLU_752032_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5255-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0614">Plasmid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGRP" evidence="3">
        <location>
            <begin position="40"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="356" mass="38117" checksum="4614905AC006B57D" modified="2008-01-15" version="1">MKQYSRRSFGKLTVGVGMSVVVGLTELQLLRPSHAAVAIPAIGGTATWGAAAPKEPIKRLAQKPIGIVVHHTTSPNSNDFTQTKARQVARSIQQSHFNRGWIDTGQHFTISRGGWILEGRHQSLAAVQQGTTHVQGAHVDGHNETHIGIECDGLYMEHAPSLPLWNNLVALLAYLCHQYGLTAQTIVGHRDLDATLCPGDTFYSLLPQLRAAVETHLAGGNVGRMWPTLKRNTPATSLAKTAQYLLRTHGASITADGAFGPATEAAVKAFQTAKGLTVNGIIGAATWESLIRTVRLGDSGDAVRAVQTRLAAQGYTTTSDGQFTATLNALVKTFQTNRQLSVDGVVGINSWNHLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B928</accession>
    <name>A9B928_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07842">
        <property type="protein sequence ID" value="ABX07842"/>
        <property type="gene ID" value="Haur_5215"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5215"/>
    <dbReference type="HOGENOM" id="CLU_021082_0_1_0"/>
    <dbReference type="OMA" id="MARWFFM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5277-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="13"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="690" mass="79920" checksum="8CC13021CE63C7CD" modified="2008-01-15" version="1">MNDTQSQTESLLDIVAGIKQRTIMLPEFQRDFRWELPQTYDLFDSLIRDIFIGTVIYGKPSFEMTLREIDTRPRKGKGANAPLVTHYYSAQQITTKSQTQNLRIVLDGQQRLTSLYRAITGEGNDSVFVILHEGIDLESVSQKSLEELVDRIAGEESRTAISVKLSLAYLSETDSSIEPEDQYQWFADTVYGRDVIQTADLDFQKKAERAYRRILTKLTDLFKQQKMVAFYLLDMSLDKFCLFFERSNSRGIQLNFTDILAAKLYHGFNLRAKIEEFESQAKIKVNREIIIRAIAYIVGSSRGRSPEIDKKYILETLNADDFNTYWDEVCRLYRECLGYLTNQHYILSQDWMPFENMVIPLMMFLRQIKSFDRMNEQQRSFLEFWYWASIFANRYSSASNATIIIDCKVLIQVAHGERIDNRSYFMRLRSLVTESLDLLSYTKKTSSIYRGILNLINYAAKGLRDWSNAQILDVSMRLEDHHIYPRGYITSKPELDIDHNEAEQLVDCVVNRTLIPKIKNITIGKKAPYTYLADLATQNSQLSLSLATHLLPKDFDSEPTWNTCFKLFLEERAQALFALIDKYVIEPLPDMIHQHAVVGEATEQPSEGRKPRFNDMVQAKKVVPGDQLYTKKYPQRRATVVDGETVEYDGVRYPINVWGEKVTGWSSINIYDSVILERTGKPLRSLREEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B959</accession>
    <name>A9B959_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5246"/>
    <dbReference type="EnsemblBacteria" id="ABX07873">
        <property type="protein sequence ID" value="ABX07873"/>
        <property type="gene ID" value="Haur_5246"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5246"/>
    <dbReference type="HOGENOM" id="CLU_377135_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5308-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="735" mass="78483" checksum="BBB8D1312C144612" modified="2008-01-15" version="1">MPDWMDNLVQQPLYQLEQTIAQVTWGFNRAGLFIIDVLDRFRAQLVSHGFTKALDTVSTEILGISRPVVELSLTIGMLLIIATPVIRFQWVNIKKVLGLAVIVPLLLPMLAGGFQDIDAARSDLGSLFYNQIFSGSSFNIAPGDANQGTDRGILVDGSGQIPAYGPRNDGRSGLRGVDIAASYLWATRADVMESSRLLPTAFEQQYFPYDIGAFGDQDSAVRWQLIERAGGGITRTVYGLILVAFAFLETLINVAFTLALGFQLIALIIATLFMWFTPFEGMVVGIIKKMADLMLQSWGISAVQGLTLAAVVGAANQSGSIAVLGVGILGLALEIVYVTVAYKAVIGAITGMGSGGGISSVGRALAPAAALATGGIGAAVGMATAAPKAAAAYATARQSGASSSAALGYAAQSNRPLAAIGNLATLMGYGNSEFTAGAAIGQNARERRYGMHSPMARHQLGMHADREQQRGERQQDRQMAMARQQQQEADRVQAMERQAQQAMVRDQAQARQAQQDAERQAERQKRMAREAYEAPIKAIGRPQITEAMTSAYVSAYASDPTSPASVDSVTSAMGLAPGAFGHQTAAVQTVLESLHQTPFAPDLAQRLMVEAGQEGQFRPDTRAEAQNDLIASGMRETAATRRMQTMEQQMQRVPGAIQVSDAEAAAALQQQSSAYAGYSAEHRQRPIERDPVITPTPERLASPPPAALTAPAEQRRTTGYGRTPRRSRAGHSATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B968</accession>
    <name>A9B968_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5255"/>
    <dbReference type="EnsemblBacteria" id="ABX07882">
        <property type="protein sequence ID" value="ABX07882"/>
        <property type="gene ID" value="Haur_5255"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5255"/>
    <dbReference type="HOGENOM" id="CLU_2523004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5317-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9855" checksum="4945F61F4EDCBB57" modified="2008-01-15" version="1">MCCHEIGHIVFNHVEPTELSLQEFITEFESGRIDQIPTIYRQHKTVFDHPWEQIAEDIGVLFIEAIERWESTLPDLAQDIYGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B979</accession>
    <name>A9B979_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_5266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5266"/>
    <dbReference type="EnsemblBacteria" id="ABX07893">
        <property type="protein sequence ID" value="ABX07893"/>
        <property type="gene ID" value="Haur_5266"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5266"/>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036805_8_0_0"/>
    <dbReference type="OMA" id="CAQLANR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5328-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="386" mass="43935" checksum="8BA5CFACD2782CE2" modified="2008-01-15" version="1">MTPSKKHTHSPVIGQAEAQASFQQLVQHQIRQAIRATFIDILEDEVAAFIGAQPYERTDERRDHRAGHRSRTLGTTAGVIDDLPVPRTRGGFRTQLFDRYQRRMHDVDTLMQDMFVGGVSQTAVGTVVEHLTGNAPSPSTVSRVFHTLDDEFQAWQARPLPPRYCYAFADGTYFSVIYNGQGQKMPILALIGITPDGQREVIAFTTGERENQGAWENLLADIKDRGVDTIDLWITDGHQAMLNAIAAKFPASQRQRCVVHKMSNIESHIPEKYRDALHAELRAIFYQPDRAQADQAAAAFMAKYERQYPSAIRCMQRDWEACLTFYAYPEGHWVNIRTSNIIERTFEEVKKRSKKMATAFRNEGSCLLLFYAVVRTLQLRKIRMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B997</accession>
    <name>A9B997_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5284"/>
    <dbReference type="EnsemblBacteria" id="ABX07911">
        <property type="protein sequence ID" value="ABX07911"/>
        <property type="gene ID" value="Haur_5284"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5284"/>
    <dbReference type="eggNOG" id="ENOG5032YPG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162353_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5346-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10584" checksum="60DFB7CA9017CF01" modified="2008-01-15" version="1">MNSPLRPAFDLGRVLLTRGINALNIPPYDLLWLIQQHTCCQWQMEAEDIEANMEAINEGYRVFGSLRFEGITIWIITEADRASTTILLPDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF2</accession>
    <name>A9AUF2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0420"/>
    <dbReference type="EnsemblBacteria" id="ABX03071">
        <property type="protein sequence ID" value="ABX03071"/>
        <property type="gene ID" value="Haur_0420"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0420"/>
    <dbReference type="HOGENOM" id="CLU_1701842_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-426-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17453" checksum="99901AB8B6C278D4" modified="2008-01-15" version="1">MQYADRSESISEYLKRCPFHNTITITNRLTSDGDRIITILNNHTIAIEIYLAKSNYCLINAGLGFNVDDIYWPNFPAISVLEYLVNGHLVEKQRMLGSTCVGVSSYVAINTDIIYSNRTFCLLGELLHVFTKATRFVQYPKLVDSKSVIDQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK6</accession>
    <name>A9AUK6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1890"/>
    <dbReference type="EnsemblBacteria" id="ABX04533">
        <property type="protein sequence ID" value="ABX04533"/>
        <property type="gene ID" value="Haur_1890"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1890"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_0_1_0"/>
    <dbReference type="OMA" id="KSIWIAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1919-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="414" mass="44054" checksum="BFF221E493959A2E" modified="2008-01-15" version="1">MKALTIAWKDTLIRFRDINALLLMILAPLVISGIMGAAFGNQSATPTISDIPLIVVNQDQGVLGQRFIEALNAGELADLLEPTIMTDAEAAKDLVETGEVRAVVLIPSDFSASLETTQTNDAGQQPAKIMVYTDPAARITPTIVRSVVTEIANVFSNTAIASEITVAQIVEQLGGNNPALANLEPALNQSLPSLTAAQPSAQVQARVISSTSANLDPIAFFAPSMAIFFLMFTMFDGTRSLLVEQINGTMSRLKSTPTGIGQILIGKLLGTFLTGSAQFVCLVVSSSLIFGLDWGDSIAGLALMLVAFVAAATGLGSVITAFSRDLPQANLLGSMITLLFGFLGGNFFMIENFPQWLQILSKLTVNRWGLDGFSDLTVRGLGIQDVFLEAGVLLGIALVCFTLAAWRLPRRFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUM2</accession>
    <name>A9AUM2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized peroxidase-related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1906"/>
    <dbReference type="EnsemblBacteria" id="ABX04549">
        <property type="protein sequence ID" value="ABX04549"/>
        <property type="gene ID" value="Haur_1906"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1906"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_7_0_0"/>
    <dbReference type="OMA" id="LNRWNDS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1935-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010195">
        <property type="entry name" value="Uncharacterised_peroxidase-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01926">
        <property type="entry name" value="peroxid_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="41"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="180" mass="20427" checksum="9759EF21EFE1DB77" modified="2008-01-15" version="1">MPRLKPLAPNEVDPESLKVFEGFFAKRGNVPNMFRTFARRPEMMIAASNLMSAVLSTGTLDLRLKEMVVVRTSQLNECSYCLTSHSTILRNLGLLQENIDALQSPDDPRWTERERVALRYAEQVTLNAKGISDELWSSLREHFDEGEIVELTATTSLFSMFNRFNDALDMAITEPGWPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUV1</accession>
    <name>A9AUV1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3905"/>
    <dbReference type="EnsemblBacteria" id="ABX06539">
        <property type="protein sequence ID" value="ABX06539"/>
        <property type="gene ID" value="Haur_3905"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3905"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_0"/>
    <dbReference type="OMA" id="RNSKHTE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3947-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="34168" checksum="6775BE9B65C001D2" modified="2008-01-15" version="1">MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPSVPGNEAAGVIAALGEGVTGWDVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDAQAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAMLQLSAVRGFKVVATVRKPEQAQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLIIYGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVDTTVALDDLAGIVRVATEGGAGKVVITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVB7</accession>
    <name>A9AVB7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1965"/>
    <dbReference type="EnsemblBacteria" id="ABX04608">
        <property type="protein sequence ID" value="ABX04608"/>
        <property type="gene ID" value="Haur_1965"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1965"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1994-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="23235" checksum="0ECD53D89C6D0037" modified="2008-01-15" version="1">MATQNPEASLNQRRRSQILDAAAQVFAQQGFHQTTIRQVAKAAGIADGTIYLYFASKHELLLGILERLNDREQREIDFTQALDSRPSGFIASYFEERVGRLMEQMTDLQAALPAVLSDVSLRERYFREIFGPTFELANPVVQLWIDQGILRPAQAELLTRSLASSILGLVLLRMLGDEVAINQWPELARTTINLVLYGILQEPPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVD5</accession>
    <name>A9AVD5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1983"/>
    <dbReference type="EnsemblBacteria" id="ABX04626">
        <property type="protein sequence ID" value="ABX04626"/>
        <property type="gene ID" value="Haur_1983"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1983"/>
    <dbReference type="HOGENOM" id="CLU_1068625_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2012-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="260" mass="28663" checksum="3DDE541A4E0E3975" modified="2008-01-15" version="1">MLCSAIHQTLDNLLVSDSFASLDAETLRHIRTCAVCRGYIEVLLAAIGGQMLPIAAEPAADHHLDEELASYIDLERLNPGQGRLRYPAVDSHLRICPDCYKEYSFMNEMLQDASLVQLTIPSPSLNPAIDPTKIWASLPASLNPTIWSWSRPVMNRLVQRIQSLSGLIQGVRGDGDLGPAFYRHTLGFGYNLAFRVLHVDDQYWQIVVALEPPLQATVVLAFGNEEFQATFSEDGLATLPPIPATLFTNPAGPALNIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH2</accession>
    <name>A9AVH2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoribosylglycinamide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2020"/>
    <dbReference type="EnsemblBacteria" id="ABX04663">
        <property type="protein sequence ID" value="ABX04663"/>
        <property type="gene ID" value="Haur_2020"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2020"/>
    <dbReference type="eggNOG" id="COG0151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029016_4_1_0"/>
    <dbReference type="OMA" id="FGACHTE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2049-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040570">
        <property type="entry name" value="LAL_C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18603">
        <property type="entry name" value="LAL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="112"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="407" mass="44418" checksum="A0838B9793EB86E7" modified="2008-01-15" version="1">MSRHFLLIGTAREVHPKIKQLGHRLSLLCPVKNIKTLKNHGDYDRIVGMAANATIDQWIEQARLIHCHAPIDVLGGFNEVTQHIAADVAAALKLPYHSSATIHYTRQKDAMRQVLREANLDPTIAQSVETADDIKVFGERYGYPLVLKPRDGRASMGVSIIRSAAEIATAQAWFEAGAAGHAMLVEEYLSGEEYSVEAFSEYGQHHIICVTQKFKDPQTSVETGHCLPAPLPQATVAEITSFVEQVLTALDLQNGPSHTEIILTARGPRIVETHARLAGDSIVELIELASGIDVDQLWIKQVAGETVFEQLPRSFQRWAAIAYASPHAIGRLERVDGQEQATHCPGVVKADVLQELGSFFQGASDSFARGAFAIATGDTATLATMQARQAAQCFRFLVNCADPSTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVI9</accession>
    <name>A9AVI9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04680">
        <property type="protein sequence ID" value="ABX04680"/>
        <property type="gene ID" value="Haur_2037"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2037"/>
    <dbReference type="eggNOG" id="ENOG5033KUP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174117_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2066-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="27046" checksum="B26AF8F56239952B" modified="2008-01-15" version="1">MITPDVFKDALLTQDYETMRFAIATGFDVNTVWQLGRPSFLQIAQTMNDMESLRILYEAGAVPDTPWLENLFKDFSRGVIRTHDGSAHNPCLQPGIRDLTENFTVLSLEYERGICHFSRGMHTIEITLKPFILDGECVQTSIQADRIALPPSLDDLLGQRFIFPRNPDAGYIDASLYLRQAHNPVYISSILFKNFVHDKRQIEVVMQMMFDFEEEMIGFANEALTLEIALFLEGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVK5</accession>
    <name>A9AVK5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2055"/>
    <dbReference type="EnsemblBacteria" id="ABX04696">
        <property type="protein sequence ID" value="ABX04696"/>
        <property type="gene ID" value="Haur_2055"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2055"/>
    <dbReference type="HOGENOM" id="CLU_2508181_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2083-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="85" mass="9569" checksum="7F32A65CC778783B" modified="2008-01-15" version="1">MAAVRLRDPDLQAKLAAVTRHEREVSHDESISQEQLVAMLIDEAHREMLAFHAAPTATIDSTNNQFTTLAMRDVTARWAKEEGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVN7</accession>
    <name>A9AVN7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4005"/>
    <dbReference type="EnsemblBacteria" id="ABX06637">
        <property type="protein sequence ID" value="ABX06637"/>
        <property type="gene ID" value="Haur_4005"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4005"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_3_1_0"/>
    <dbReference type="OMA" id="QGADEMM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4047-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="622" mass="70318" checksum="206790D5B0B5C4C7" modified="2008-01-15" version="1">MCGITGHLEWHGTAQTAILEQQTEAIRHRGPDSAGFFCVAQVALGMRRLAIIDLTSGDQPMFSRDGDLALVFNGEIYNFQALRQQLQQLGQHFATNSDTEVIVRGIEQWGILGCVQRLNGMFALAIWQQQAQRLTLVRDRLGIKPLYWYSDAQRLVFGSEIKAILAHPAVPRQINLQGLANYLSFGHSLAPQTMLQAIYKVEPAHILTWDVASRAMQTQRYWQLQPNPIAIAPAEAAAECYSRLREAVRLQLISDVPLGAFLSGGLDSSIIVGLMQRLGAAPINTFSVGFEHAGFNELPDAALVAQHFGTKHHELRLNANDLVGALQTLVYHYDEPFGDAAGLPVYLVSRFAREHVKVVLTGEGSDEQWAGYRRYQAELIARMAQYLPGRSAIAALIRQLPRNRRLKQAIRTLDQRDPGRRYAAWLTIADVQQRQRLLQPHISAVLGDYAPEQIYDQVYPRSGAAMTNMGLADLQTWLPDTYLEKVDKASMAASIEARVPFLDHTLVEWTMNLPPTLKLRGTKTKWLLRQAFGEMLPQRTLRKPKHGFAVPTDPWFRGALSNWTAEILFDQRTLSRGLFNPHEVQRIYQAHRDGKETADTVLWLLLNIELWQRIYLDREERL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV4</accession>
    <name>ATPB_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit beta</fullName>
            <ecNumber evidence="1">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpD</name>
        <name type="ordered locus">Haur_4072</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AVV4"/>
    <dbReference type="SMR" id="A9AVV4"/>
    <dbReference type="STRING" id="316274.Haur_4072"/>
    <dbReference type="PRIDE" id="A9AVV4"/>
    <dbReference type="EnsemblBacteria" id="ABX06704">
        <property type="protein sequence ID" value="ABX06704"/>
        <property type="gene ID" value="Haur_4072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4072"/>
    <dbReference type="eggNOG" id="COG0055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022398_0_2_0"/>
    <dbReference type="OMA" id="GFNMIMD"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000143516" description="ATP synthase subunit beta">
        <location>
            <begin position="1"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="152"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <sequence length="471" mass="50910" checksum="F0B01076211A9BFC" modified="2008-01-15" version="1">MATGKILQITGVVIDAEFPADGLPQIYNALEIPLGEGRSSLICEVQQQLGDSVVRAVAMSTTDGLVRGMDVIDTGAPISVPVGPETLGRVFDVQGRPIDGEGAVGTTKTMPIHRPAPTFEEQSNRAELFETGIKVIDLIAPFTKGGKTGVFGGAGVGKTVIIQELISNIAKEQSGYSVFAGVGERSREGNDLIHEMKDSKIPGTDQTVFDKTVMVFGQMNEPPGARLRVALSALTMAEYFREEGRDVLLFVDNIFRFTQAGSEVSALLGRMPSQVGYQPTLGTEMGELQERITSTKTGSITSLQAVYVPADDYTDPAPATTFAHLDATISLERSISEKGIYPAVDPLASTSRILDPNIVGEEHYRVATEVQRMLQRYKDLQDIIAILGVEELSDDDKLTVSRARKLERFFSQPFGVAEVFTNIPGKYVAVGDTVKSFARVLAGEFDHIPESFFFMKGGIDDVVAAYDASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW08</accession>
    <name>A9AW08_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0598"/>
    <dbReference type="EnsemblBacteria" id="ABX03246">
        <property type="protein sequence ID" value="ABX03246"/>
        <property type="gene ID" value="Haur_0598"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0598"/>
    <dbReference type="eggNOG" id="ENOG502ZK7M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2752296_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-607-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="70" mass="7915" checksum="8C455B957C239A6E" modified="2008-01-15" version="1">MQQLTLKPEEVPANLAEWLRASQQTTILLAVELDADGYLSLQALPEVDPQLVPRVRKAMAQYAETLRRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWI2</accession>
    <name>A9AWI2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4109"/>
    <dbReference type="EnsemblBacteria" id="ABX06741">
        <property type="protein sequence ID" value="ABX06741"/>
        <property type="gene ID" value="Haur_4109"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4109"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_3_0_0"/>
    <dbReference type="OMA" id="QTLYHRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4155-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="243"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="405"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="477" mass="51646" checksum="6981124BE6F52946" modified="2008-01-15" version="1">MATLYEIWRLALPPTTSLRAGEANTLAVRAVVLARPTQPALPDLAGSEVVLVSTTVLDSLRLSLARLIERLNGTSVLAVGLTGMVDERAVAAAETANITLFELPHNADLRMVQRESERLLSDPEAQYERRAAQLYSALTTNGLSEGRTTLLRMLELWTGHSVVFPADAGMPTTVPVLLDGHRVGFLGSIGSHPWDAGALEQGSAALSLLLDKERAIEATEDRLRGSVLESLLAGIPLDVPGQRRAAEQGILLDSAYALAALRPQDSLQIDRVMAAVRRACDRLRYPAFIADHDGIIVLAMPIDSLDNPEQRLREVHSALHEASWVLDGGFGIASENGAWSGAWAEAIGALRLGRELLGAGVLAGGAELGVYRLLLSVADSARARMFYDRTIGPLAAHDAKQDGDLLYTLQMFFAYLGNHSQAAAALHIHRNTLLYRLGRIENITSHHLDRAPDRLALQLGLALHRIYQSQKPDLKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWL2</accession>
    <name>A9AWL2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">argJ</name>
        <name evidence="8" type="ordered locus">Haur_4139</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4139"/>
    <dbReference type="MEROPS" id="T05.002"/>
    <dbReference type="EnsemblBacteria" id="ABX06771">
        <property type="protein sequence ID" value="ABX06771"/>
        <property type="gene ID" value="Haur_4139"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4139"/>
    <dbReference type="eggNOG" id="COG1364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_1_0_0"/>
    <dbReference type="OMA" id="DYVHENS"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023517361" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023517360" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="185"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="395" mass="40269" checksum="A6892F5B7838E3F5" modified="2008-01-15" version="1">MSIFRFAAGFRSAAGRCGLKASGNPDLSLLVADNVCTGAGVFTTSLVKAAPVLYDQAVLAEHASEIRAIIANAGCANACTGAQGDAAAREMARLAAEAVGCEPHQVLVLSTGVIGHQLNVEKVAKGVAAIAPELGVEHAPALSEAIMTTDTRPKTSSATAVIDGVEVTVAGVAKGAGMIHPMMATMLSIVTTDAAIDADLAQSLLREVTDASFNCVTVDGDPSTNDTLLLLASGVSGVTINASNIAAFRQALEIVCIDLAKQIAADGEGATKLITITVDHAPSVAAARTVARKIACSPLVKTAIHGGDPNWGRILAAAGVAGVPFDPSHVELWLGEVQLVAGGTPTNYNEREAASQIGGQQVAIRLNLGAGAATGYAWTCDFSAEYVRINADYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWN7</accession>
    <name>A9AWN7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4164"/>
    <dbReference type="EnsemblBacteria" id="ABX06796">
        <property type="protein sequence ID" value="ABX06796"/>
        <property type="gene ID" value="Haur_4164"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4164"/>
    <dbReference type="HOGENOM" id="CLU_1893325_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4210-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="134" mass="14179" checksum="C3DBFB3E3217898D" modified="2008-01-15" version="1">MIANARIRLIGLVGLGALLGAVGAFMAYQSRAIAPSPEQLKPYVWAVVAVPLGSFIGSLLGQWRLYRPFAGWLGLTYLLSLFAAARLERVFVGQEAAVANGHASYLILAIILQSIGALLVAWRLSATATSTPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWW1</accession>
    <name>A9AWW1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0714"/>
    <dbReference type="EnsemblBacteria" id="ABX03362">
        <property type="protein sequence ID" value="ABX03362"/>
        <property type="gene ID" value="Haur_0714"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0714"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_0"/>
    <dbReference type="OMA" id="TSWQALK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-726-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="36931" checksum="C6412EBFCCBCA7B1" modified="2008-01-15" version="1">MMKAFFIERYGNKDRVRAGDLPIPELRDTDLLIQIHAAGVNPLDNKIRDGEFKAILPYRFPLILGNDVAGVVVKVGAKVQRFKLGDEVYARPAADRIGTFAEFIAINEADVAIKPKKLSMAEAASFPLVGLTAWQALIEQAQLKKGQKIFIQAGSGGVGTIAIQLAKHVGAIVATTTSKANFDFVKRLGADIVIDYKTEDFETILKDYDVVLNSQEGAIVEKSLRVLKPGGTLISISGPPDPTFAQEIGAKWPIRMLLRFLSYRIRKKAKQRQVRYSFLFMRAHSEQLSELSSLIDAGIIHPVVDRSFAFEATKEALDYVETGRVKGKVVITMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX26</accession>
    <name>A9AX26_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA or RNA helicase of superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2194"/>
    <dbReference type="REBASE" id="16530">
        <property type="entry name" value="HauORF2194P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04834">
        <property type="protein sequence ID" value="ABX04834"/>
        <property type="gene ID" value="Haur_2194"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2194"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002151_1_1_0"/>
    <dbReference type="OMA" id="PPYNANQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2222-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041635">
        <property type="entry name" value="Type_ISP_LLaBIII_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18135">
        <property type="entry name" value="Type_ISP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="286"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Type_ISP_C" evidence="2">
        <location>
            <begin position="657"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1021" mass="118151" checksum="8FCB299629CB8CB6" modified="2008-01-15" version="1">MPTIAPKVLNTYRVELARVMKVGGLNEGAIRNAFQNLLSEAGRAWGMTLVAEQTLTLGSRKALRFDGELRDSLKLRHGIWEAKDPADDLEREISNKLRAGYPTKNTLFENSRQAVLYQHNQRVLSIDMHDDHQLVRLLETFFSYAEPQVDDFHLAVARFRREIPDLATSVAEIIANELKHSRDFKLAFDSFVALCRSSLNPQTSEQQVEEMLIQHLLTERIFRSVFDNPDFVRRNAIAAELEKVIAALPKRAFSRDKFLASLDYFYKAIENSARTISDYSEKSTFLNTVYEQFFQGYSTDIADTHGIVYTPAPIVRWMVTSVEQLLRDQFDSSLSDKGVHVLDPCVGTGTFMLEILNQLQNSTLEHKYRHELHCNELLLLPYYIAAQNIEHEFYDRTQNYAPFEGLCFADNLEMEANKRQASMFVPENAQRVQQQQDAPIFVIIGNPPYNVGQQNENDNNKNRKYPHIDARIRQTYAKSSKASLQTKLYDMYSRFFRWATDRLGDNDGVIAYVSNGSFVEQIAFDGMRKELLKDFTSIYVLDLGGNVRKNPKLSGTTHNVFGIQVSVAITLLIRNRAQYPQRQQAELHYARLDEWWWRGEKYSYLNQHADYRAIAWQQLQPTSNGTWITEGISDDFATFVPIGSKESRSGSAGAEPTIFNTYSLGVSTNRDTWVYDFNREALAKRMQTFITTYNTEVDRWHNRQTEVALDDFVLQDDTKIKWSRNIKRDLKRSKKVSFYENNVLLSLYRPFTHRYIYFSDVIIDEMSKMGLFFKGANTSICVTGVGSEKPFSFFISNYISDLNFYGGGSATQWFPFYIYDEDGSNRRENISDWALQHVQAHTGNNNFDKWDIFYYIYGLLHVPSYRERYAANLKLELPRIPLLAPSVIEQLSAAGRQLAELHLNYEQQREYKLKHNENCNVPWTWRVEKMRLSRDKSAIIYNQALTLEGIPVEVYEYRLGNRSALEWVIDQYQVSTDRRSGITSDPNDLDDREAIVRLLKQVITVSLKTIAIIQQLRAISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX87</accession>
    <name>A9AX87_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative serine protein kinase, PrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4175"/>
    <dbReference type="EnsemblBacteria" id="ABX06807">
        <property type="protein sequence ID" value="ABX06807"/>
        <property type="gene ID" value="Haur_4175"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4175"/>
    <dbReference type="eggNOG" id="COG2766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028588_2_0_0"/>
    <dbReference type="OMA" id="DFYGMED"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4221-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016230">
        <property type="entry name" value="Ser_kinase_PrkA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000549">
        <property type="entry name" value="Ser_prot_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="29"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="692" mass="80487" checksum="C86C716A01B6D844" modified="2008-01-15" version="1">MTTPSGSQLMSLLSTLQDQQNYQNLNWAGSFQDYLDIVANNPKVTRNAFQRIYDMIMSYGLEEFIDAKKKLIRYNFFTTNEFDEQDAIFGLEIPLMRLVNFFKAAAHGYGTEKRVLLLHGPVGSAKSTIARRLKRGLERYSRSEEGALYTFDWFLGDIEDLDAGKVKDADWDPCPMHEDPLHLIPMEMREAFLNEFNANLEPDDHITITGDLDPSCRYNFRDLMRRYNGDFAKVLRHVRVRRFVFSEQDRVGIGTFQPKDEKNQDSTELTGDINYRKIAIYGSDSDPRAFSFDGEFNIANRGIIEFVEMLKLDTAFLYDLLGASQEHRIKSKKFAQTHIDEVIVGHTNEPEFRKLENNEFMEALKDRTVRIDIPYITRLRDEIRIYEKDFNSENVRVHIAPHTIEVAAMWAILTRLEEPKRANLTLLQKMKLYNGKSLPGFTEDNIKELRKESRREGMEGISPRYIQDKISNALVNYQSDGGINPFMVMNELESGLKTHSLITNEEDRKRYRELLAIVKEEYADIVKNEVQRAISADEEAIKRLCANYIDNIKAYTQREKVRNKFTGAYEEPDERLMRSIEEKIDIPDNRKDDFRREIMNYIGALAIEGKTFDYRTNERLHRALELKLFEDQKDSIKLTSLVSSVVDKDTQEKIDVVKTRLIRDFGYNDQSATDVLNYVASIFARGDATQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXH7</accession>
    <name>A9AXH7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="5" type="ordered locus">Haur_0743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0743"/>
    <dbReference type="EnsemblBacteria" id="ABX03391">
        <property type="protein sequence ID" value="ABX03391"/>
        <property type="gene ID" value="Haur_0743"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0743"/>
    <dbReference type="eggNOG" id="COG0333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_1_3_0"/>
    <dbReference type="OMA" id="HRACRHC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="63" mass="7163" checksum="096C352F6BBB690C" modified="2008-01-15" version="1">MGALPRRKITREQRGHRRQHLALTAPSLSACPNCGGYRRPHRVCLNCGTYKGRQYLKKDNAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ5</accession>
    <name>A9AXJ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0761"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03409">
        <property type="protein sequence ID" value="ABX03409"/>
        <property type="gene ID" value="Haur_0761"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0761"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_0"/>
    <dbReference type="OMA" id="SCEMARD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-773-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="272" mass="30400" checksum="86AFD109F3CBBD0E" modified="2008-01-15" version="1">MLQPTPTNAQTASGQDPDLSVIIPCFNEQKRIIPTINTIIDYLNSLGRSWELIVSDDGSSDQTISLVEAQRYPNLTIIKSTRNYGKGHAVRAGIIAARGNFILFTDADNATPITELDTMLPLLELGSYDIAIGSRAKQLLQTKQRSLGRCMMSAGLRVIVEHGLKLNIHDSQCGFKLFHRTVAKHLAQVQTINSFAFDLELLVIADIFGYQTIEIPVDWVDIAGSKVHPIRDAYQFLRDIMSIQINHWRGRYPSSLPKTPKSKSPQSNHWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ1</accession>
    <name>A9AXQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03465">
        <property type="protein sequence ID" value="ABX03465"/>
        <property type="gene ID" value="Haur_0817"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0817"/>
    <dbReference type="HOGENOM" id="CLU_2450550_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-831-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="89" mass="9155" checksum="BDB399A1345CD958" modified="2008-01-15" version="1">MLKPIFGIARVLIAAQVGSYLGDTPKHGAGTPKGLALGPVNVTLSNVAPAAVVGLLCGNSMIYSLLTSYALSSIIGDKFEEKVLQQIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY28</accession>
    <name>A9AY28_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4278"/>
    <dbReference type="EnsemblBacteria" id="ABX06910">
        <property type="protein sequence ID" value="ABX06910"/>
        <property type="gene ID" value="Haur_4278"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4278"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_0"/>
    <dbReference type="OMA" id="GPRMPRD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4330-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="312" mass="33528" checksum="515579DC9DE02A82" modified="2008-01-15" version="1">MARYLVTGGAGFIGSHLVDALLQRGDEVRVFDNFSTGYEHNLAHCINDIELVRGDLRDAEAVSQAVAGCEVIFHEGALPSVPRSVSDPLTTDAVNTGGSLHVLQAARQHGARRVVFAASSSVYGDTPILPKVETMAMSPKSPYAVSKMAAESYLKVFHHVYGLETVGLRYFNVFGPRQDPTSQYSGVIARFMTLALQGEPYTMNGTGNQSRDFTYVANVVQANLLAASVPAAAGHVFNIACGLRISLNDVVAMLNKLVGKELPIIYSPARTGDVEHSLADISAARQILGFEPSVDIETGIARTLDWYRTQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY86</accession>
    <name>A9AY86_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4336"/>
    <dbReference type="CAZy" id="CBM34">
        <property type="family name" value="Carbohydrate-Binding Module Family 34"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06968">
        <property type="protein sequence ID" value="ABX06968"/>
        <property type="gene ID" value="Haur_4336"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4336"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_6_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4389-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02857">
        <property type="entry name" value="E_set_CDase_PDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004185">
        <property type="entry name" value="Glyco_hydro_13_lg-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735322" evidence="4">
        <location>
            <begin position="28"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="5">
        <location>
            <begin position="404"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="914" mass="98545" checksum="DE295D4F7936BFF7" modified="2008-01-15" version="1">MRNKRFGGLLALVLLALALLPNPKSVAAGDNNVHWDELYHAAPSANPRTELVPGESFSFQQAEVNGTIVSTTNVQISILALAGDLTSAQIRYWNGTEQIVAMSKVKTLTASFRNTASTSYDLWRGTIPAHAAGSTVYYRVRVYDGSVLALLKAQNGSYTNPRGQHVRGANYDPDDYSFTVQSGGMPTATPTIAPTATRTATPSATATRTPTPVGTISATPTPSRTPTATATNTSTPTVSATPSGACSGAAVGNNTIISSAVYHDSTNSVYRDPLGSLQAGQSASIRLRTCSNDVSAVSLSVWLTGAPFSQPSFSYPLTVVSNDGTYAMWQASVPAPSSSTDQWYQFKLTDGSTIGYYVVANTSNTGPGVWSATALDRSWKLGTVPAPPQDYAVPTWLQDAVIYQIFPDRFRDGDSSNNFNNVRVYGPNTCNGYSGAGAPNCLASIHSNWNETPTTPGYGIDFYGGDLQGIVDKINAGYFNDLGVNVLYLNPIFDASSNHGYDTNDYYGINPRFGNLAKFDEMIAAADAKGLKVILDGVFNHAGMDSIYLQGYPGYKTDRWTGINGACESDSSPYRSWFTQGSAGTSGSYPCVGGWGWKGWYGYETIPEFIENDPVKQFFYRDGSAQSPNGKSVTRFWLERGIAGWRFDVAQDITHAWWSDMRPYVKNGYGDSESLLLGEVTGGCDWGLYRAYLNQNELDSVMNYCFRDWAVSFANGNAPSSFDSSYNAFRAQMPASPWFGMMNLVSSHDSTRALRLLNDDKARMKLMVLLQMTLPGAPSVYYGDEVGVTGGGDPDNRRTYPWADKGGSPDTVMYAHFKKLIALRRTYPALSSGDVATLLVNDASKLYGYRRWKGTQEAVVVLNNGTANQTATVNVSHLANGTVLTDVLNGGSYTVSNGQLTLPVAAQSGVVLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY94</accession>
    <name>A9AY94_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4344"/>
    <dbReference type="EnsemblBacteria" id="ABX06976">
        <property type="protein sequence ID" value="ABX06976"/>
        <property type="gene ID" value="Haur_4344"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4344"/>
    <dbReference type="HOGENOM" id="CLU_1710767_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4397-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="16777" checksum="3CEECBCC5A43CB8B" modified="2008-01-15" version="1">MIIRGDQADLIHNHEGRLAPNQQRQLQAMRAFRVPFLPMLLIGLALISYGTLRFDTLGWVVAGLGGVLIINAWVRRQSQAALKAGVVQAITGELEKIQPVPFAMFESELVINKRSYALLAKLGNQPLQVGQPYTIYVAKGVSRMGIIVAVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYA0</accession>
    <name>A9AYA0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CpXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4350"/>
    <dbReference type="EnsemblBacteria" id="ABX06982">
        <property type="protein sequence ID" value="ABX06982"/>
        <property type="gene ID" value="Haur_4350"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4350"/>
    <dbReference type="HOGENOM" id="CLU_1308721_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4403-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025682">
        <property type="entry name" value="CpXC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14353">
        <property type="entry name" value="CpXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpXC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="210" mass="23655" checksum="0B17D229A891BCBB" modified="2008-01-15" version="1">MRSRHEVAVVQCPACGAQFDAPLWLILDAEEQPGLVQQLFDGRLRETQCPYCDALGSLTAPLLYHDARYEQLILALPLSVASASEAEALAQQLVGLLHSRLELEKLDQAEYLAHVQLAADLDDLQLMLIHASYRRELIALMATIEWPIHQLATIDQFETLLQSHDRDHHQAFWQSLNADQQSDLTLLFDRLAAVVPIDSGLSDFLRRLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYB5</accession>
    <name>A9AYB5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MazG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0849"/>
    <dbReference type="EnsemblBacteria" id="ABX03497">
        <property type="protein sequence ID" value="ABX03497"/>
        <property type="gene ID" value="Haur_0849"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0849"/>
    <dbReference type="eggNOG" id="COG3956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038356_2_1_0"/>
    <dbReference type="OMA" id="HMERHWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-863-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="149"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="296"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="42210" checksum="1816DF79BD27958E" modified="2008-01-15" version="1">MLSQLLTQLPLDLSQGFQVVPAHKLLAPIPAPAEGADRAWCELQNIAEYPSFVSPLPFQATQALIITEIDVSKLATVRASLLRRYPAEHPVHNLNETGLSQQTLATASSAQAWYLPALSIETDVASPSTLEWIMARLAGPHGCPWDRKQTHASLREFLLEETHETLEALDAEDWPNLKEELGDLLLQIVFHAEFGRQAGRFNLDQVYTAINSKLIRRHPHIFGTTEVSDADEVLRNWDAIKATEHQEKGSQRESALDGIAKTLPPLATAQLIGKKAAKVGFDWPDVSGVWAKVHEEIAELQAATSPEEQAAEFGDVLFALTNLARWLKIDSESALRGTITKFRRRFVAVEQAAQAQGRQLSQLSLSEADTLWEAAKRAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYH1</accession>
    <name>A9AYH1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0905"/>
    <dbReference type="EnsemblBacteria" id="ABX03553">
        <property type="protein sequence ID" value="ABX03553"/>
        <property type="gene ID" value="Haur_0905"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0905"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_0"/>
    <dbReference type="OMA" id="YIQTHIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-919-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="138"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="26931" checksum="9B3AFB4CA22AA009" modified="2008-01-15" version="1">MAEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLPQLDGLEVLRTIRQTKSTPVLMLTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALLRRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQELDLTPTEFAILDLLLRNPGRAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZB9</accession>
    <name>A9AZB9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_1017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1017"/>
    <dbReference type="EnsemblBacteria" id="ABX03665">
        <property type="protein sequence ID" value="ABX03665"/>
        <property type="gene ID" value="Haur_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1017"/>
    <dbReference type="eggNOG" id="COG2224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019214_2_0_0"/>
    <dbReference type="OMA" id="LEKDWAE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1034-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="90"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="311"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX03665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="430" mass="47247" checksum="EB351B145D3D605C" modified="2008-01-15" version="1">MNTTNGISTTELERGWATDARWQGIQRDYTAEDVVRLRGSVIIEQTLARMGAERLWDLLHTEDYVHALGALTGNQAMQMVKAGLKAIYLSGWQVAADANMAGQMYPDQSLYPANSVPQVVKRINQTLQRCDQIYHSEAKDGTYWFAPIIADAEAGFGGPLNAFEMMKAMIEAGAAGVHFEDQLSSEKKCGHLGGKVLIPTSHFIRTLQAARLAADVMDVPTLVVARTDANGAYLLTSDVDPRDREFCTGERTPEGFFCIRGGIDSAIARGLAYAPYADLIWCETSTPDLEEARKFAEAIHAQYPGKLLAYNCSPSFNWKRNLDDATIAKFQSELGAMGYKFQFITLAGFHALNYSMFDLATGYRDQGMSAYVQLQQAEFNRESEGYTAVKHQREVGTGYFDLVAQAVSGGMSSTTALSGSTEHEQFVGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZG0</accession>
    <name>A9AZG0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibronectin type III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2466"/>
    <dbReference type="EnsemblBacteria" id="ABX05104">
        <property type="protein sequence ID" value="ABX05104"/>
        <property type="gene ID" value="Haur_2466"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2466"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_236094_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2493-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1255"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1525"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1625"/>
            <end position="1715"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1887" mass="200603" checksum="329CCE3E4FAB7F07" modified="2008-01-15" version="1">MMDSATLSRHRIVRTITLLILTSFILGLFAFTLQSTAAQTTPTASDKAYGWLQAQQLPNGLVDSFEHGGAADDLCVVYDQAVAAIAFVVKADYDRARAVLTALRGSQWDDGSWHNIYACSNPNQVMEWHRDVGPAVWVALAVASYEAATGDLVTYREMALRAVNFGFGFQQDDGGVNGGFEATQQGYRFHSWGSTEHAIDLYAAARYFYGDQPRTGQVKQFLETVVWDSVDGRWLGGRADLRDPLDVNTWGVAALGDEYIMALEYALATHRVTLGGIDAVDFNSDRNDIWFEGTGQLIVALQAVGRTSDAQYFLQQMAKGQKANGGIPYSLQGTNNGYWTMSTANAVSSAAWLIFADAAFNPLGVGTATITSVAPTPDPVVVEPPVSASDKAYGWLRSQQLANGLVDSFEHGGAADDLCVVYDQAVAAIAFVVKADYDRARAVLTALRGSQWGDGSWHNIYACSNPNQVMEWHRDVGPAVWVALAVASYEAATGDLVTYREMALRAVNFGFGFQQDDGGVNGGFEATQQGYRFHSWGSTEHAIDLYAAARYFYGDQPRTGQVKQFLETVVWEAAKGRWLGGRADQRDPLDVNTWGVAALGDEYIMALEYALGTHRVTLGGIDAMDFNSDRNDIWFEGTGQLIVALHAVGRTSDAQYFLQQMAKGQTANGGIPYSLQGTNNGYWTMSTANAVSSAAWLIFADAAFNPLGLGTATITSVAPTPDPVVVEPPVSASDKAYGWLRSQQLPNGLVDSFEQGGAADDLCVVYDQAVAAIAFVVKADYDRARAVLTALRGSQWGDGSWHNIYACSNPNQVMEWHRDVGPAVWVALAVASYEDATGDLVTYREMALRAVNFGFGFQQDDGGVNGGFEATQQGYRFHSWGSTEHAIDLYAAARYFYGDQPRIGQVKQFLETVVWEAAKGRWLGGRADQRDPLDVNTWGVAALGDEYIMALEYALGTHRVTLGGIDAVDFNSDRNDIWFEGTGQLIVALHAVGRTSDAAYFLHQMAKGQTANGGIPYSLQGTNNGYWTMSTANAVSSAAWLIFADAAFNPLGLIGDDQAPTAPTNLTASLITATTAQLAWNAANDNIGVEGYAVYLNNAATPATECRAVRTTQCTLTSLNPLTTYSITVKAFDAAGNVSLASNSINITTPDVDRIAPTAPTNLNATNVTAASILLSWTASSDNVGVVGYNAYLGTNPIAVTSCNGVITTVCNLTGLAPDTQYSITVKAFDAAGNASLASNSILVTTLIDTQAPTPPLNLQVLAKTTTTVDINWTASSDNVGVIGYNAYLGTNPIAVTSCNAVTATMCSLTGLTPNTQYSITVKAFDAVGNVSAASDGLVVRTNPLPTFGNPWYLLDGATHITPSQLSTTSGNAAASDSIPAASATNIDGQATQTISYEAENLTASYDSSKTTEFELFIDAGTAVGNGTQARIAYDFTGDGTWDRIETYNYFATDPVNSWERYTHTRGLRSATGSFANLTNGKVKLELWNAIGNNPSLIRTNASSADGQQSTLVLPFLVTTVDNEAPTAPTNLLRGVTTANSAAFTWQAASDNVGVVGYSAYLNGSQVAVANCQMVTGLGCNLTGLSANTSYSVVVTAFDAAGNQSEASASITFTTSDLDSIQPTAPTNVAIANIGATTATVSWNAATDNLGVVGYSVYLNGADQAASGCSMVDALNCTLSGLNADTSYTLVVTAFDAAGNQSEPSATVTFTTQANPFRSQLYLLDGASQTADGILSVIPGNAADSDPLASAQNGNWDGLPTNAITYQINDLTATYDPAKTTQFNLYLDAGIGVGNASQVRVSYDFTGDGTWDRIETYNYFATDPVVGWELYNHTRGLRSATGSFANLTNGRLKVELWNAIGNGGSLVRTSATTADGQQSTLTLPFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZK9</accession>
    <name>A9AZK9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2515"/>
    <dbReference type="EnsemblBacteria" id="ABX05153">
        <property type="protein sequence ID" value="ABX05153"/>
        <property type="gene ID" value="Haur_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2515"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620763_0_0_0"/>
    <dbReference type="OMA" id="NSIVWEN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2543-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735138" evidence="2">
        <location>
            <begin position="30"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="46116" checksum="8A178FFA51D8F3D5" modified="2008-01-15" version="1">MNTWWKIRSFGVLVLLGLVFGLAPQPSQAGGVVYVVPGGAGSQTGTDWANAKDLQEAIQSSTTGTEIWVKQGIYRPTAGTDRTAAFTLTSGIQLFGGFAGDETSRQARNPSQNPTILSGDLLGNDVGAASQSNPTRSDNSYHVLYCITKPEPMLIDGFVISGGQATNQIFPQNMGGGGLFDRCNLTILNSRFISNAGLFGGGILNFNTSLTINQSIFAGNWALSTGGGLENQQNGIVNLRSSAFVGNISQQNTVSAIANASGTLNLHNSIVWENNGIAPINGSNNNLNLNVSYSIVQGGFIGTGNSSSDPQFVDADGADNLVGTLDDDLNLQANSAARNTGNPSLLPSDQTDLDGDNDVSEAIPLTIDYRPRINEGFVDMGPYEYQGNEPTITPTATATPSPTVTATATATATVMPSETPTPTATAEIPPTTQIYLPAVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZP5</accession>
    <name>A9AZP5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ordered locus">Haur_4467</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4467"/>
    <dbReference type="EnsemblBacteria" id="ABX07099">
        <property type="protein sequence ID" value="ABX07099"/>
        <property type="gene ID" value="Haur_4467"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4467"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025574_2_2_0"/>
    <dbReference type="OMA" id="IAMPGKA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4522-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX07099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="357" mass="39040" checksum="7641B833FA5DEC15" modified="2008-01-15" version="1">MRRLIRALLIVATIGALVVACVATLFLRELTQPAGESNIAQDFTIAPSESLAVISSNLESEGLVRRAIVFRVFADLRNAETDLYPGTYKISPNMTINQILEMFRVAPEVQTAVRFTVPEGLRIEEIAAVIESTGVVSADDFLAVARDGSQFKADYSFLSSLPDSATLEGYLFPDTYEIFSDATSEEIIRKMLDTFAIRWADSPLSSATTGRSVHEVVTLASIVQREASNNEEMPRIAAAFWNRLKPEFAGNQLGADPTIQYILGESGNWWPKLDQLTVEQINSAAGPYNTRVNPGLPPGPISAPGLFALQAAASPAAEDVTYFVTKCVAAGERPTHNFTNDYSEFLQFQEEFLACPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV8</accession>
    <name>A9AZV8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4531"/>
    <dbReference type="EnsemblBacteria" id="ABX07162">
        <property type="protein sequence ID" value="ABX07162"/>
        <property type="gene ID" value="Haur_4531"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4531"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388654_0_0_0"/>
    <dbReference type="OMA" id="GERIAYW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4586-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="646" mass="70791" checksum="355B72BA197C1120" modified="2008-01-15" version="1">MRERYRFVEQLGKGGFATVWLAYDQQIGGLCAVKQSIAAESEVVEMLEAEATILAGLAHPSLPRIRDHFVHEGRACVVMDYIEGVDLSVLLATEHDGIAPKRVVEWAQQLCTAVQYIHTLPQPVLHRDIKPSNIKLTPDGRLVLIDFGIARDLKVSSLGLRRAVTAGYSPPEQYRGQTDARSDIYALTATIYALLTGRAPLAAPARLIGESLPAPSALRPSLPSALDQPLLRGLAIEPEARQQSAGQLALELMTAWRSVQPASPKLPNIRTKPLIQARTWRHWLGLGLVGSLSLGGFSATIWSLLNQQNAAEASPNWQTYFPALLNNSATSAPLLTPTPAPTSTPAPTATPAPTSTIQPLIAGLTGYFFVGMREEDGDYQIYRIPAMGGEPQQLTTLGSNYGGVVSPDGRQIAFTSERDGREQVYVMKVDGSDQRRVTNDPGRCEYPSWSPDGKQLAYAHRRLDDLKENSSTIYIQALDQTEGQQLTKMWGTMPTWGQQGIVFTSRDIVENIEQLGLAIIQPDGSGLKIINPTRDRDEHYAEWSPDGKSIAYVAGDSQRTITRQIWVMNADGSNPHPLTKGLGGVTQPRWSPDGKWIVFLAKWGMPDDLQNNRPRFNVWVVSTEGGPAKPFTISEANKFGLGWGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZY9</accession>
    <name>A9AZY9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1048"/>
    <dbReference type="EnsemblBacteria" id="ABX03696">
        <property type="protein sequence ID" value="ABX03696"/>
        <property type="gene ID" value="Haur_1048"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1048"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040419_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1065-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032267">
        <property type="entry name" value="DUF4832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16116">
        <property type="entry name" value="DUF4832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_42" evidence="1">
        <location>
            <begin position="78"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4832" evidence="2">
        <location>
            <begin position="303"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="484" mass="55737" checksum="02E40C2F83DC0E9C" modified="2008-01-15" version="1">MRWFRVLFVLLIVAGFGLTWYLLQPQNSLVWQTFTPTVIPLEQAELANPGRGLYQWRGQTMICPSELISNRERYDRWTWAELEPNENQYDWQEIHQLLDMAEQNGQRVWLGLGASAGPSNNGPFLPIYLQKPEFGANFEGDWYPNYNHPFVQNRLEALLAAFVAEFAGDQRILGVQMRSYGRYGEGYLPWNADKSHGMWASESTARWLVDAWHTRLSPHFLISIPLSNNPVFYYAMTKQPYWSITRDALGMPEQMGNIDQLIQSDITVDGQAIGPLVAERWKVAPMFSEMIGEYGERDYSGQFLAAQTQVISYHISYVSNGNFAQPYRASPWDFWRDPINCPEQASNWSNADIENFMLAGKLAGYRYAPTTIKLAIDNQQLQIESSWQNAGVAPIYERWPLVWQLRDATQTVVWQGESSLDLRQLLPAQAYEHRQQFEQFKLPAGEYELRLVAPAINRYVRPLQLAIEGQLDDGAYRIGILSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B021</accession>
    <name>A9B021_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1080"/>
    <dbReference type="EnsemblBacteria" id="ABX03728">
        <property type="protein sequence ID" value="ABX03728"/>
        <property type="gene ID" value="Haur_1080"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1080"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_3_0"/>
    <dbReference type="OMA" id="FYSGMRD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1100-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="322" mass="34674" checksum="7E6321195FB53768" modified="2008-01-15" version="1">MSIVYDILIIGGGPSALAAAFYAQNKQLRTLMIYADLGGKAGWAHNRTVNGTINVLPGHDLVERLISQLSNHQSSVAHINDRVVGLRKTNSMFVVDTQQYGERYARSVVVASGAAPNRLPLPGIQHLFGVGLGYSITTFAHQTQGQRVAVYGVTPRTIRGVAEIVLGSNHIYWVSPDEDLPEVPLVDAIRRMPNVTIIPQATIRDVVGINSVKQIVIERGTSLQHIPVDRLFVDIGIQPNTGFLNNGNVDVLDEDGFVIVDEYNSSPCHGIFAAGDVSNSVLGEQVLIAIGDGVRAAVSAYEYLLVHKLTLEEVSHAAGKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B024</accession>
    <name>A9B024_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1083"/>
    <dbReference type="EnsemblBacteria" id="ABX03731">
        <property type="protein sequence ID" value="ABX03731"/>
        <property type="gene ID" value="Haur_1083"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1083"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_2_1_0"/>
    <dbReference type="OMA" id="AYVFEWL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1103-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="449" mass="49120" checksum="B7A186FC1B6ABD9D" modified="2008-01-15" version="1">MSYSIVIIDPDQGSAQTTAARFQRRWGQNVQVNIVKQADWASVQAHSPNLVVIDPAPYRLHGLRLLEQLCEEQPSTAIAVVASGSSPSMRQRLRNLPITSYLEKPSSLAPLLGELDHLVESNVALQSKGGLVMERQMLIPLDGSLLAEQALDYAVVLARRNSSVLHLVRVIGYPPLVPAYEWPVPSAVDSRQWLADERQAAQTYLDELKARYEQQGLAVRTTVLDGEPAHAIVQFATEQNSVREIVLASHGRSGLGRWVLGSIAEKLVQATPVPILVIHGDERKVETFKIPPELRTIVVPLDGSAIAEQALPLASQLAEAHSAELVLLSVTPGIDDPGLIESGLVPMWSAGEKAQARDQAQKYLQQLEQSLQTPRLRLRHLVVSGTPAEMIDEIAQEAVASMIVMATHGRSGFSRMWMGSVATKLIRSSQRPIFLVRAVEQAAERGQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F3</accession>
    <name>A9B0F3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2624"/>
    <dbReference type="EnsemblBacteria" id="ABX05262">
        <property type="protein sequence ID" value="ABX05262"/>
        <property type="gene ID" value="Haur_2624"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2624"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_729143_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2652-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="41103" checksum="D7A7488F4F75EECF" modified="2008-01-15" version="1">MQIAALLAEARQALSVGDRAKAKQFASQALRLDSKHIETWLLLADLVEVPAQKRDCFQRILAIDPTNAQAKQALNQLDAPAPVAAASFELPKSAWFGSKSAEPELTAQVGGPIATAPLATNAPSGIRPLGSSQAASLVELSNTAVGGTTPTGYVQPIQPSYNQTNYPQPNQAYSLPAASYGQAQPQYGQVTYPYVEPSGAAKFLKWLVFATLGLIVVCAGIGLMVNFGKEPPPTPKVSAQDRTTAMLGDTMKIIVNPDFYDKSKQKAIVEPYLNNYFIEAARTNTGRLDQTVLDSFDNGVDQQAFLAALPYIKDAYVTPTQYTVESQTNEMITLKLISGDLVFTFHNGKFLQVPLKDTYDTFTWVNDDGRWYLAGISLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y4</accession>
    <name>A9B0Y4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1206"/>
    <dbReference type="EnsemblBacteria" id="ABX03854">
        <property type="protein sequence ID" value="ABX03854"/>
        <property type="gene ID" value="Haur_1206"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1206"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_3_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1228-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="139" mass="15335" checksum="CF5A8DF0D0F77603" modified="2008-01-15" version="1">MSYSLAFSQAIAISLYITYKIEEQIYDFVPTHEIADFLGIAKPSVVKVVQSLTNAGLIETREGAKGGVRLTRNSQAINLLDIFNAIEQAKPLFRLNIHPTEPKIEALAARQRMVASLQRAEAAMKQELQAVTLADLYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B113</accession>
    <name>A9B113_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2653"/>
    <dbReference type="EnsemblBacteria" id="ABX05291">
        <property type="protein sequence ID" value="ABX05291"/>
        <property type="gene ID" value="Haur_2653"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2653"/>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062599_0_0_0"/>
    <dbReference type="OMA" id="SMTIQEF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2683-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="96"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="38569" checksum="8DC4C70AAE9D2A41" modified="2008-01-15" version="1">MHYPMRGCMLVVMDAHATPEDIQAVCTVIEDMGLQANTMPGPTRTAIGITGNKGAIAEAARLKLMPGVRDVIRVTAPYKLVSREYREADTIIEINGVQIGGPSLVVMAGPCSVEGRKQLLTTAEAVKAAGATILRGGAFKPRTSPYSFQGMGEDGLKLLAEARELTGMPVITEVMDTEQVDLVAEYADILQLGARNMQNFALLKRVGRTRRPVMLKRGLSSTVKDWLLSAEYIMAEGNQAVILCERGIRTFDDHSRGTFDLSVVPVLRELTHLPIIVDPSHATGRWQSILPMARAGIASGADGLMIEVHPNPAEAWSDGEQSLLPERFVELMEQVERIADAMDRPIQGRTKAATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B122</accession>
    <name>A9B122_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ordered locus">Haur_2662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2662"/>
    <dbReference type="EnsemblBacteria" id="ABX05300">
        <property type="protein sequence ID" value="ABX05300"/>
        <property type="gene ID" value="Haur_2662"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2662"/>
    <dbReference type="eggNOG" id="COG0319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106710_3_0_0"/>
    <dbReference type="OMA" id="RMRIHPL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="174" mass="19819" checksum="269C512813F319EA" modified="2008-01-15" version="1">MLELTAHIEVVPTDLALDTSLLEQVVAQVLADEGQTGTWEIGIRITNDQELHELNRQYRGVDRPTDVLSFGEYEDDDDDFIVPDGVYDDDEFDDPEADEAAYLGDLAISYERVLAQAQEYAHSSRRELCYLVAHGTLHLLGYDHETDEEREDMRQREEKALSTLGITREAEPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B143</accession>
    <name>A9B143_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2683"/>
    <dbReference type="EnsemblBacteria" id="ABX05321">
        <property type="protein sequence ID" value="ABX05321"/>
        <property type="gene ID" value="Haur_2683"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2683"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138490_0_0_0"/>
    <dbReference type="OMA" id="MSNLMGA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2713-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="13624" checksum="7185920D304E14D3" modified="2008-01-15" version="1">MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSFVGRLISDIAAMARLMGTTVVITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITENNADGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1B6</accession>
    <name>A9B1B6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigA</name>
        <name evidence="7" type="ordered locus">Haur_4672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4672"/>
    <dbReference type="EnsemblBacteria" id="ABX07303">
        <property type="protein sequence ID" value="ABX07303"/>
        <property type="gene ID" value="Haur_4672"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4672"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_0"/>
    <dbReference type="OMA" id="YWWISEE"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="141"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="5">
        <location>
            <begin position="220"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="309"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="43295" checksum="26D0220E51F0BE00" modified="2008-01-15" version="1">MGAARQHRYLTHDQVLLHLPPSDKNTALFDELCVRCQAEDIPILEEPPTAAVHLRSRDVDDDDLERSLIREGVSLDDPVRMYLREIGQVHLLTAHEETMLAKQLERGERAMIRLARHEYLLEEKARLQQQVLESEAARQHLIQANLRLVVSIAKKYVGRGMSFLDLIQEGNIGLMRATEKFDYHKGFKFSTYATWWIRQAITRSISDHSRTIRLPVHVGETINRVKRTAHKLQQALEREPSAEEIGEALGLPADKVRRVLEVARQPVSLETPVGNEGDSVLGDFIEDDRSSEPLDHATEHLLREQLDEVLCKLDERERRIIELRYGLVDGKYRTLEEVGREFGITRERIRQIEAKVLRKLRHPAFGGRKLRAYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1L9</accession>
    <name>A9B1L9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_1256</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1256"/>
    <dbReference type="EnsemblBacteria" id="ABX03904">
        <property type="protein sequence ID" value="ABX03904"/>
        <property type="gene ID" value="Haur_1256"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1256"/>
    <dbReference type="eggNOG" id="COG3202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_608035_0_0_0"/>
    <dbReference type="OMA" id="VTIHPHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1278-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX03904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="450" mass="49568" checksum="F786BD86DB4CB0F7" modified="2008-01-15" version="1">MLKRLEQGLKLRPNEWRLVLTLMGLLALNTLVLELADVVAMAGFISSLGTEQLLWLWPVGMLLTIVAAGSYALIVDRTERVRLIQRLLAGFGACYLAILGLFWLSAPAWLIYPALSILNEQQYAIFPLAFWALANDIYATSEAKRLFPLLGAGATIGSLLGNGLAALIATWLVGSDQQNTSLVLGLCAVLCFLGIGQVWLMFHKHPVRARQSKTERESIRETFKVGADVIRHVPLFSLLALVLFTTGLALTVVEFHFLRSIDQIAAADPLRFQQVYGSYKLAFVVMLLAFQWLLAGRLLSTTSPKQGFIALPIVLLLCILGALVQPLIGGLIGRFGARLAQSGWDEPLRKSVQSIIPDERRGRVSVFLDSYCYSFATIVGCGVISVLLLPSWLGELAASVSTLIYLGFAAVATAVGLWAAWRIRHVYDKSLLNWRLSRSRRRSVLDGIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1P9</accession>
    <name>A9B1P9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1286</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1286"/>
    <dbReference type="EnsemblBacteria" id="ABX03934">
        <property type="protein sequence ID" value="ABX03934"/>
        <property type="gene ID" value="Haur_1286"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1286"/>
    <dbReference type="eggNOG" id="COG2453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047330_3_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1308-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022778">
        <property type="entry name" value="CDKN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05706">
        <property type="entry name" value="CDKN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="104"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="21182" checksum="48D7ED90338903A6" modified="2008-01-15" version="1">MTNKSLWHQINEPTMPATPISASYWVLPGCLLAGEHPMLLEKEPLHERLQHFSKAKITVFIDLTEETETQELGDYSAALHQIQASPALVRHHFPIPDMHIPSIPQIQAILAQIISALDQQQNVYVHCWGGLGRTGTVIGCLLVEQGWEYAQALAQIVNLRQATRDSRYPSPSNDLQRQFVADWAMQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B210</accession>
    <name>A9B210_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4729"/>
    <dbReference type="EnsemblBacteria" id="ABX07360">
        <property type="protein sequence ID" value="ABX07360"/>
        <property type="gene ID" value="Haur_4729"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4729"/>
    <dbReference type="eggNOG" id="COG3910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079631_2_0_0"/>
    <dbReference type="OMA" id="MSHGESF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4787-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="37"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="30144" checksum="7FECE6BC155363C0" modified="2008-01-15" version="1">MLLASLTIKPPAAHDAEQFPLNVPAIQALVGQTFDFEAPVTIIVGDNGSGKSTFLEGLAVATRSISVGTYDLERDQSLTSAQRLAKYLKLSWHKRTGRGFFLRAEDFFGYAQRLNQLRLEAEAGLCEIEADTTLSPLARAQARQTHSRTLGELRHHYGNGLDHMSHGESFLRLFQSRFVPNGLYLLDEPEAPLAPIRQLSLLALIRDAVEQQQSQFVIVTHSPIIMAYPKARLLQISPTGLQPIEYNAIEHVSLLRDFLNHPERFLRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N1</accession>
    <name>A9B2N1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2844"/>
    <dbReference type="EnsemblBacteria" id="ABX05482">
        <property type="protein sequence ID" value="ABX05482"/>
        <property type="gene ID" value="Haur_2844"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2844"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_4_3_0"/>
    <dbReference type="OMA" id="WVVLRGM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2875-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="30286" checksum="65219E8D377AF994" modified="2008-01-15" version="1">MNQLLEPLSFSFFRYGILAALLIGSLCGLLGVYIVLRGMSYIGHGLSHAIFGGAVVSFVLAWNFYLGAGLWGFAAAVLINQTARRTKINADAAIGVITTASFAVGVALISRYRNFTRSFDAALFGNILGVTSDDLWAIGGVCIMVGLVVFFSYKQLLFMTFNNDVAQVYGVRTNWLDTLFSLMLAATLIVSMKILGVTLIAAALVIPPITARLLTDSFHRMLGLSTLIGGLTGCIGMYLSYFFDLASGATIVLTQTSCFVLALGIAALRKQLRNRMIHTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N9</accession>
    <name>A9B2N9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2852"/>
    <dbReference type="EnsemblBacteria" id="ABX05490">
        <property type="protein sequence ID" value="ABX05490"/>
        <property type="gene ID" value="Haur_2852"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2852"/>
    <dbReference type="eggNOG" id="ENOG5034C5Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1358875_0_0_0"/>
    <dbReference type="OMA" id="GEMRITE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2883-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="201" mass="21201" checksum="F5CCEF052AD3CFEC" modified="2008-01-15" version="1">MGYGYGYAPPPPPRRRGCLFGCLTTLTIFVFLALGGLLGVYFYLRPMLSEQAGNTLGGQLEQQIDRKLDEQLGGPNSEIPAGFQGVVQVTDTEINQYIQANPNEISPLDSATVRFTPGRLGATVGAYGMTGSASAGVQVTADGRIDVVDAQIDGALGFFLDAEQLAQTLETKLNSQLTANGQRITAIEVGEGVLTATVEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P1</accession>
    <name>A9B2P1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05492">
        <property type="protein sequence ID" value="ABX05492"/>
        <property type="gene ID" value="Haur_2854"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2854"/>
    <dbReference type="HOGENOM" id="CLU_1978462_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2885-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735410" evidence="1">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="126" mass="14005" checksum="3F03A33CF21648C3" modified="2008-01-15" version="1">MRNVVQWFVFASLLIVLGACAMNSTPTPIVNPAPIEYPQTKPDSLILAYGVPHVQFAQHWVRIASYDRVSESMLVEIRPHRDTTGVEQSLKVGDSLTIGNQHYRVLALQAPQSGLGWLEIDSQPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2P3</accession>
    <name>A9B2P3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2856"/>
    <dbReference type="EnsemblBacteria" id="ABX05494">
        <property type="protein sequence ID" value="ABX05494"/>
        <property type="gene ID" value="Haur_2856"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2856"/>
    <dbReference type="HOGENOM" id="CLU_486417_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2887-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021454">
        <property type="entry name" value="DUF3105"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11303">
        <property type="entry name" value="DUF3105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="560" mass="62356" checksum="225DDB34C8CC3F42" modified="2008-01-15" version="1">MEPTNWQREVEQALAQNDHNRAKQLLAAVIRQNVHEREAWRILASIVNDPAQQAECLRRIAAIDAATPTVIKPIKPIAAVAPSTELPSDPSTSPTTPLVAVQDTPNFTPSSIQTEPLFDSQASFTLPANYSMGQATQKLDQPMPQPARSLPKMLMLIGASLCGLGLLLLLGLQFWPLLNDINSTPASEQPLLAVVELTIVRSGVGQVPMTDQAMVYFEIENPSDQALYNIPYTMTLTSQFDKVLKNTNTIELLLPKQKIVVVDGIFTGDSFRAKSVEISLGQGYPITIDQPIPQVEALTPTTFGMPFRGRLQESWGYEYPTYHVSAIATDSGVVTSTLVSMLFYDTNDQIIGAGSGYIDYINKKTSLPNTRRGETMVYPIIWGTSEVDRVEIVPAFTLATFSQQPPIKPKKAEIDQMWLGEYIPEVDPPYHVQGIVEYPTLPPTSGYHAMVPAEWGHYDNFITDEAMVHNLEHGAVIIFYNPQLITANELGQLEATFENLYQREHHTILQKRFDLDATVAMTAWEYRLMLRDNVNLDAVNTFFSEHIARGPECVNLRCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Q1</accession>
    <name>A9B2Q1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfite oxidase</fullName>
            <ecNumber evidence="8">1.8.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_2864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.1" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2864"/>
    <dbReference type="EnsemblBacteria" id="ABX05502">
        <property type="protein sequence ID" value="ABX05502"/>
        <property type="gene ID" value="Haur_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2864"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_5_2_0"/>
    <dbReference type="OMA" id="WARHVQF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2895-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022407">
        <property type="entry name" value="OxRdtase_Mopterin_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00559">
        <property type="entry name" value="MOLYBDOPTERIN_EUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="49"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Mo-co_dimer" evidence="7">
        <location>
            <begin position="247"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX05502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="363" mass="40253" checksum="F18FF708918979CB" modified="2008-01-15" version="1">MRDSLPSFDVAKSATMQVVQAEPFNAGTPLDELASSYIQPTSQFFVRTHGTIPSLDPETTTIQLQGLLAQPLSISIADIKQQLPYVEQVSTLQCAGNRRQEMHAYQPIYGELPWGANGLSTANWGGAPLRSLLERCEIDSTALHLVFESYDQVERHGQTFGYGGSIPLNEPMIEHALLAYTMNGTALPALHGGPLRLVIPGIVGARSVKWLRSIEFSSEPSHNYFQRRAYRLAQSSEPEAWQNAPMLHELPVNAVLYLPTADQTLLAGTITLAGYAITGGQALVEQVEISLDHGQHWQHARLIDPPRLGCWSRWQIELELTAGEYQCWVRATDSLGQQQPEQPAWNVKGYHHNAIQRIQLSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V7</accession>
    <name>A9B2V7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cellulase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3384</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3384"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06020">
        <property type="protein sequence ID" value="ABX06020"/>
        <property type="gene ID" value="Haur_3384"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3384"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041401_2_0_0"/>
    <dbReference type="OMA" id="WKDIEGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3421-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735415" description="Cellulase domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="5">
        <location>
            <begin position="79"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="45434" checksum="EBE043A5D91438B4" modified="2008-01-15" version="1">MPKSRWLSAAMVCLLAVNLLAACGGDSAPTTQPTNPEAATATPETAAPTTDSNLPVTTGNPLQLPYLQYGAAAQLYYTDRNRALTLMNNAGFDWVRQQIQWKDIEGPKGNFGWGELDAIVADANAKNIKVLLSIVRSPSWARADGTNGMPDNIKDFGDFVEALVVRYKGKVQAYEIWNEQNLDHENGGSRDSIDATKYVDLLVEAYNRIKPIDPEAFVISGALTSTGDSPAAIDDMTYFEQMFSYKDGIFKDHIDGVGFHPSPSYNPPATLWPDQPGPGPGWLESPTHYFRHIENLKILMDKYGMQDYQVWVTEFGWATQNTSPGYEYGNEISFEQQGQYVLDALQMTRRDYPWVATMFVWNLNFAVTSPDPLDQTASFGILNPDWSPRPVFEKIQGFVNAVKTEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X1</accession>
    <name>A9B2X1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone family protein DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3398"/>
    <dbReference type="EnsemblBacteria" id="ABX06034">
        <property type="protein sequence ID" value="ABX06034"/>
        <property type="gene ID" value="Haur_3398"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3398"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_1_0"/>
    <dbReference type="OMA" id="PAHEGIN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3435-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="9765" checksum="E258CE19B14A5909" modified="2008-01-15" version="1">MHQSDLIKAIAEKSGLSQAQAGKAVNALLESITEALAAGDRVVLTGFGTFEVRERQARTGFNPKTREPLEIPATRAPAFSAGSNLKKAVTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Y4</accession>
    <name>A9B2Y4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3411"/>
    <dbReference type="EnsemblBacteria" id="ABX06047">
        <property type="protein sequence ID" value="ABX06047"/>
        <property type="gene ID" value="Haur_3411"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3411"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086011_0_1_0"/>
    <dbReference type="OMA" id="YILIDYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3448-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041494">
        <property type="entry name" value="PIN7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18475">
        <property type="entry name" value="PIN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN7" evidence="1">
        <location>
            <begin position="7"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="21863" checksum="5BDE4EA91C49940F" modified="2008-01-15" version="1">MRTNFVLIDYENVQPATIESLNHEHIKLLIFVGANQTKVPIEIAVALQQLGSRASYVKISGNGSNALDFHIAFYIGQLAAQEPSAYFHIVSKDTGFDPLIQHLKSKKIFANRVQNVNDIPRVKIALASTLDAQVEVIITSLQGNKSSKPRTIKTLSSTINAIFLKKLSEAELEALINQLKTMGLIEVDDTKVSYKLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2Z1</accession>
    <name>A9B2Z1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH dehydrogenase</fullName>
            <ecNumber evidence="2">1.6.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.99.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4824"/>
    <dbReference type="EnsemblBacteria" id="ABX07454">
        <property type="protein sequence ID" value="ABX07454"/>
        <property type="gene ID" value="Haur_4824"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4824"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_4_2_0"/>
    <dbReference type="OMA" id="VNAQPWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4883-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="208" mass="22266" checksum="0C2599E1EDE51F91" modified="2008-01-15" version="1">MTQPAVNNTLSVAEAISSRRSVRKYTNDQVSQADLNTILELTGKAPSAWNIQPWRFVAVRNQEVKNKLQAAAYGQGQVGSAPVVIAVYSNTAEALDTLADVIHPGVPAEQRQGAIDGILGAFAQRSPEEKEAWGLAQTNIALGYLSLAARSLGYDTSLMLGFDPAQVKEILGLPTHVQLAGLVALGVAAEEGYPHHRHAVEKITQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B329</accession>
    <name>A9B329_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4862"/>
    <dbReference type="EnsemblBacteria" id="ABX07492">
        <property type="protein sequence ID" value="ABX07492"/>
        <property type="gene ID" value="Haur_4862"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4862"/>
    <dbReference type="eggNOG" id="COG1183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049944_3_0_0"/>
    <dbReference type="OMA" id="IFFDFFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4922-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="24647" checksum="667D36A9D7620A7F" modified="2008-01-15" version="1">MKFRRSWVPNLVTSGNLFCGFLAVIAAVDGQAFKAAVLICLAASFDTLDGRAARMLGVSGEFGKELDSLADVVSFGTAPALLIYQISLREVGWIGTIAAGIFVCCGAGRLARYNLITSSDKRFFVGMPIPMAGMTAASLALYTGALNPYVATALIGFTGFLMISTLRFPSVEQIAFETFLPIRIAFIVIFVLALARPSQFLYVLPLSYISYGMIANIVWAIRGRGSRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3F4</accession>
    <name>A9B3F4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Multi-sensor hybrid histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_1473</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1473"/>
    <dbReference type="EnsemblBacteria" id="ABX04117">
        <property type="protein sequence ID" value="ABX04117"/>
        <property type="gene ID" value="Haur_1473"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1473"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_271678_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1495-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="158"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="369"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="441"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="530"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="899"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1257"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="865"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX04117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1380" mass="157340" checksum="31809DED039C88C8" modified="2008-01-15" version="1">MTCYANESLLELQLKQQVSLLETELQHVRSHTAKLQALIDHTESLIWSIDSSQHLIMSNRTFHDYLHQWYDQHIELGQPMSMLHLPKPIAKPWNEAYRRALQGEAFAQEFVHHYAGATRYYEFHFAPILDEQRVVQGVNISGRDISSRRLAEVMLRSSEARYRAINEAAPYGVFFCDTQGQCVYANTALLHMLEVKLEDVLGDAWMEFLHPKDASDSESFWHNLALSVNQQPIPSVLFDQTVRLHTKLNQLIWLRLRISPVIEAGVLCGFVGITDDLSALKKAETAAQAKQHFIQKIADTLPSQLFIYDRASASLIYTNEVSRQWFKSFNIDPSDMNTIRPLFHPDDHAIIRKVLQGRTVTSSDPQLIVDFECRLRSPEGIYRYFALRMTPFVIDADGTVSQLLGVASDITERKLQEQQIRQLNEQLEQRVIERTQELAQSYRFQRTMIQHAPSIIISLDAGGVVRGFNRAAEFEFGYQETELLGRPFPTKLFDRSDLRYRWETEQHRNRGLFYSDLDILLAEARRGVAEPHEWQAIHRSGSRFPLELTITPLLHADVLEGFLLIGNNIAARKRTEEEFHLLYRTTRSVSEAADFNSALEVVLRNICAAIGWDLSVAWVPDANQDFLALAPIRWSSNERFQHFYTYLQSLELPQGAGLAGRVWQTKHSANYAIEHDHWTEGNLNQRGYELAQQVGLQSAVAVPILANDQVVAILEFFRSSRGVDHERTTNLISVIATQLGTLFQRKHAEMQLRQSEAKNRALLAAMPDLMIRFTLKGEILDYHTNDPSDLFLPQDAMIGANAHNHQPQPQILNIMSATQRAIETNSTQNVEYELTLPKGNTVFEARIAPSANDEVVMVIRNITERKRIEQTLQQQTDELSIANAELAKAARLKDEFLASMSHELRTPLTGILAFTEALRYDQYGALNQAQAQALQQIDENSRHLLDLINDILDLSKIEAGKLTINHQSMLIDEICQASIRMVQKLAQNKQLELLYEPCAADAMLCADSRRLKQMLVNLLSNAVKFTPAGGRIGLSVKLDSQFHQVELTVWDTGIGINTQDIPKLFRPFSQLDSKLSRQYAGTGLGLALVYHMANLHGGRVELQSEVGVGSQFRLVLPWYGNAEIVEPTEQPMLLAVTEDRTLNMQLAAYAEQLGLALRFCKPYFDVQAYLQQPNQTLIYDLRQTSLSQQLFEQLRHQTAAHPVILFCDQDFKLDLTIPAHWHCMYQPLNQARLLNALQYIDSRYQLPQKLPINQAKQILFAADNLANSLLIRDFLSEFGWNVNLVYNQHDIYEAIANQPIDLLMLDLQLAGGDALQMVNTIRRHKRYYDLPIIALSALAILDQPQLAEQADTVLYKPLNLVELEQLINTLCNQQRSLDRE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B457</accession>
    <name>EFTS_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor Ts</fullName>
            <shortName evidence="1">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tsf</name>
        <name type="ordered locus">Haur_4960</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B457"/>
    <dbReference type="SMR" id="A9B457"/>
    <dbReference type="STRING" id="316274.Haur_4960"/>
    <dbReference type="EnsemblBacteria" id="ABX07590">
        <property type="protein sequence ID" value="ABX07590"/>
        <property type="gene ID" value="Haur_4960"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4960"/>
    <dbReference type="eggNOG" id="COG0264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047155_1_1_0"/>
    <dbReference type="OMA" id="DAGMMDC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000116747" description="Elongation factor Ts">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="1">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <sequence length="198" mass="21945" checksum="42D6B40AEE018A19" modified="2008-01-15" version="1">MSISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGRIEVYVHPGNKVVAIVEVNCETDFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVEREREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQEFVKDPSVKIKDLVQEAIAKLGENIVVRRFSRFEVGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B491</accession>
    <name>A9B491_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07624">
        <property type="protein sequence ID" value="ABX07624"/>
        <property type="gene ID" value="Haur_4994"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4994"/>
    <dbReference type="eggNOG" id="COG3459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023780_0_0_0"/>
    <dbReference type="OMA" id="TERSICE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5057-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731873" evidence="1">
        <location>
            <begin position="23"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="804" mass="90658" checksum="D29892C669709131" modified="2008-01-15" version="1">MRRVFCWLGCLLIGLSFVPSHTSTVAATYQVQAEFQQFWQANGGAAIFGQPISEALWFDSQLVQYFENQRLHLVNNQVVPAKLGLELFQASRRTWQNQRQHLPTSQCLRVETTERSICEPFRRYWQANGEASRLGNPITETVSETNPLTGQQQIMQYFEQQLLISTNQQIMLSPLGRWQADWLLNGTRQASPIRANLTGPSQPLKPLDQFEIQIDAGNYNGAANLRIFDSAGQLETSQTLNLTGQSQTLAFQAQGALGQHYAVLLIDGKVAAINSSIYQLEATTSLQTGVAAYDTLPNKVRSFLRNDLSIYQYQGYTIRGYRSPDSYLIWLRDHVHQGLGYRYFEQDMTSTLDYFRREQKPNGAFDDYFAMLGGAPVQGRTAVEADLEYLFVQGVHQAWQATGDTSWMLEQKPAMLRGINYSLSDPQRWNPTLRLIRRPYTIDTWDFEYGGPTIAPDGKTSPRHWIDEKTRFGIMHGDNTGMAHGLYLLSKLELTQANFEQATQWLVRSQQLTKQLNQVAWNGKFYTHNVLEQPFDIPELDEARQLSLSNSYALNRYGMEASKALAIIDEYYQRRVADSSSLSSEWFSIDPPFPAESFGTLPGWGNVPGEYVNGGRMPLVGGELARGAFRWGQPAYGFDILRRYAQMIEAQGGSYLWYYPVGNPGISGPDTLATDGWGSTAMLAALIEGAAGVTDQSALYQHAVLSPRWIVEPDVQQAQVTTRYAASQGYMSYRWQRQARGFQLDFTGSAEQVTLQLLLPNDAPQHVNLTINGLPSFGHERTIGQSRYLELRLNKATGSIMVNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C0</accession>
    <name>A9B4C0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0025"/>
    <dbReference type="EnsemblBacteria" id="ABX02677">
        <property type="protein sequence ID" value="ABX02677"/>
        <property type="gene ID" value="Haur_0025"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0025"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073173_0_0_0"/>
    <dbReference type="OMA" id="SWISHAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-25-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="116"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="238" mass="25479" checksum="CC671F84536870B8" modified="2008-01-15" version="1">MTFSTPIHTNDQSFERVLNTGYPLMVVWSSKTDPQSQAFDKVLNLLAIQFEGRALIVKVNPEENPKLTKDYAISAIPSAVFIRQGEVQGRCVGGLSKEQLQPVLEALVNGQALGNLPNAASTPLTPAAAVAGGSTPLTLTDANFEQTIRSGQTVLVDFWAAWCGPCRAIAPSIESLAKEFAGRAVVAKLNVDENPRIAQRFNIQGIPALLVFKGGKVVEQVTGAQPLPALRQVLARHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E7</accession>
    <name>A9B4E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0052"/>
    <dbReference type="EnsemblBacteria" id="ABX02704">
        <property type="protein sequence ID" value="ABX02704"/>
        <property type="gene ID" value="Haur_0052"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0052"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_791737_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-52-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="232"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX02704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="350" mass="39008" checksum="B464F75F05D72E69" modified="2008-01-15" version="1">MSADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFTGVVVISISQYWIRKGYPRRGAFFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILIGFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLSLIIQIIVVLSMLIVTALVINMAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILADTVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAIYVLGAKVFLTGIQPKTAHIFVDLDLHTALPSTYATIADAIEDLTALHRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4F9</accession>
    <name>A9B4F9_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cellulase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0064"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02716">
        <property type="protein sequence ID" value="ABX02716"/>
        <property type="gene ID" value="Haur_0064"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0064"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034735_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-65-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="68"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="544" mass="62664" checksum="A4A919959BA083BB" modified="2008-01-15" version="1">MACAMQRSRFFQFQSLLWLLIAGVCAGGLAAWSWLENEQWRGVATSVDQPIAWANVPQGGVNLPSLHLESPEVISRTLDTAKAAGFYWLRVQFPWEDIEIHAKNDFRDYRHDYNGDGMVDQTDAISAWTKYDGIVAAAQARNLQLIVRLDRPPSWARQNLPMDSFRVAKRQQDPGSTGPPDNYGDYGDYVTAVVERYRGKVRFFQIWNEPNYGHEWNWADPNPDEFFKLLQLGYTRAKAANPDAIILFPSLTPADGFDWQAMNDLQFLEQLYQLGAADYFDIFTAQGYGLGQPATENRYVRPLFNADGSLRRDTLWQRPLDSRTDVTRVVFLREVMERYGDAHKAVWISEFGWNSSAVATQYGPPVSEEQKAQYLVEYLQRARQQWPWLGAMNIWFLRPGVNFSPEDPTIHFALLKNDWTELPAYTAVKAYLTQAPQLGIGRYQPNDLLWQQGEYSANWWGEHLIVQSAGPIEVVVDGQVLAEPEFRGELGQHQLEIRGDWQALTISRQRAWWWLWASIPFGLWLGLLLALKRFYRVLVRKRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G7</accession>
    <name>A9B4G7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0072"/>
    <dbReference type="EnsemblBacteria" id="ABX02724">
        <property type="protein sequence ID" value="ABX02724"/>
        <property type="gene ID" value="Haur_0072"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0072"/>
    <dbReference type="eggNOG" id="ENOG5033I4N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857110_0_0_0"/>
    <dbReference type="OMA" id="VWYGHAP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-73-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735255" description="DUF4129 domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="3">
        <location>
            <begin position="226"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="301" mass="34108" checksum="6C61FF7F9A85A980" modified="2008-01-15" version="1">MDRIWRITACLLLFGWLLAQPLTAMAQASEVSVSEYTQLLREAFTAAQRNDEIGLREVSDKIIALKQLRTADNQTLAVNHQWLKDSLASNTPNLLLIRERLAAMLEALTAGRETGPQDLETLKVILNNPPFDALNPERNQSRPDFDFGFLSWLFNDGLTGCFTIIALVFVVGLLGYIVSTVRRNSVSVARRKAPAEEQKLTSVQAIERADKVAAEEGDFRDAVRYLYLSTLLWLEERGLLRYDRTLTNREVLAAVPSNSPLHQRLAPVVQTFDRVWYGIAEVDQGTFDQYRQQVTTLREVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4M2</accession>
    <name>A9B4M2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1544</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1544"/>
    <dbReference type="EnsemblBacteria" id="ABX04187">
        <property type="protein sequence ID" value="ABX04187"/>
        <property type="gene ID" value="Haur_1544"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1544"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096770_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1568-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="20065" checksum="798C33CA7C778F4C" modified="2008-01-15" version="1">MSSPKSWILSLYYFLTFGGFVAMAVYLPTLLTDLFGISKTDAGLRTAGFVLVATAARPFGGVLADKIGGTTILKWVFPITTCMAGLMAFSNVMPFTIGALGMAAAIGLGNGAVFKLVPEYFPQSVGIVTGLVGAAGGLGGFFPPLLLGYIRQQTGSFSYGFVALAMFTLVCWFVLYYNNRPRRPTPQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R8</accession>
    <name>A9B4R8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3003"/>
    <dbReference type="EnsemblBacteria" id="ABX05641">
        <property type="protein sequence ID" value="ABX05641"/>
        <property type="gene ID" value="Haur_3003"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3003"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="OMA" id="EHDMRFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3035-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="29547" checksum="9566ED133BEF176C" modified="2008-01-15" version="1">MAPLLLARGITKRFGGLTAVSDVSFEIEKGSIVGLIGPNGAGKTTFFNMITGLYTPSDGDMIFDGQRINGTKPSEVTKLGIGRTFQNIRLFAHMTALENVLVGQHCRMHTGLLGTLFRTPSMRAEEKEARHKAFELLEYVGLGRNSADEMAKNLPYGDQRRLEVARALATNPKLLLLDEPTAGMNPKETDALTKLIYQVRDERDLTVLLIEHDMKVVMGISERVTVLDRGIKISEGLPREVQTDPKVVEAYLGTGHAAKGKGGGAPVFDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A3</accession>
    <name>A9B5A3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02728">
        <property type="protein sequence ID" value="ABX02728"/>
        <property type="gene ID" value="Haur_0076"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0076"/>
    <dbReference type="eggNOG" id="COG1408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025443_3_2_0"/>
    <dbReference type="OMA" id="LGDYPAG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-77-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="60"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="297" mass="32489" checksum="ABFA23EED2423260" modified="2008-01-15" version="1">MAAALSRRSFLKIMGYSALATTATTLGAAAYGFQVEAEWLSIHEETIVLPRLASAYDGYRIAHLSDIHIDDVLMTREHWLTTVRMVNAQKPDLIAISGDFITHDPSRFTEDLAAGLAMLEAPDGVVGVLGNHDYWGDGNGETVRQVLRTTGITDLTNRAISLNRGSSKLHLAGHDDLWPNPIGPNDPSTMKPVLDRLVAELPKTDAAIILVHEPDTADFTASYNRFDLQLSGHAHGGQVRVPVKGALLLPYLGMRYPDHRYDVGSMVQFTSWGLGCSWPQVRFGCRPEIVMLSLACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A5</accession>
    <name>A9B5A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0078"/>
    <dbReference type="EnsemblBacteria" id="ABX02730">
        <property type="protein sequence ID" value="ABX02730"/>
        <property type="gene ID" value="Haur_0078"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0078"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067342_0_0_0"/>
    <dbReference type="OMA" id="KMGQPNR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-79-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023856">
        <property type="entry name" value="Bacillithiol_biosynth_YpdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04018">
        <property type="entry name" value="Bthiol_YpdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35941" checksum="29B06E4CBA516616" modified="2008-01-15" version="1">MQSYDVIIIGAGPSGLSAAIAAQQAGFNYLVLERGAITNTIIDYPLQTVFFSTAPNLTIGNVPWSSIHPHPTRTEALAYYRGVVEHFQLNVQMYEPVQALERLSDGTFQLHTTRHDQTSARYAARAVIVASGSYDTPNRLAIAGAELGKVKHYYREGHPFYRQNVAVIGGGNSAAEAALDLYYHGANVTIIHQFAGLDQRIKPWIAADLKAWIEAGKIQTFWEANLSAITPTSIHITSAAGSQHEQANDWVFALIGYRPNTSMLEAVGVTVDQDAVPSHNSTTFETNVPNLFIAGVLAAGAHPSKIFIENGREHGPAIIAELRQRWAGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5A8</accession>
    <name>A9B5A8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PBS lyase HEAT domain protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0081"/>
    <dbReference type="EnsemblBacteria" id="ABX02733">
        <property type="protein sequence ID" value="ABX02733"/>
        <property type="gene ID" value="Haur_0081"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0081"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053482_0_0_0"/>
    <dbReference type="OMA" id="QIELAYA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-82-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="334" mass="37250" checksum="44E1986C4D49133D" modified="2008-01-15" version="1">MTEEQNERDIEEALAEIGDHNRPIVLSELKVFNDLDQDETEIFEIEWLRIEPSHRRNLAQAMQEVGEASLELDFRAVFSILLTDQDPAIRIAAVKGMAEDTRRSSLRRLSELLTTDPDDGVRANAAITLGAWALRAGEGNLDQRTSNELLQTLWAVFDDRQTSTLVRQRLLETLGYLADSDPRVNQEIGAAHQRLDDGWQAAALCAMGRTGLDQWLPTITASLRSHEPLLRFEAVRAAGELGDLAESIVNHVARATADGDVEVATTAIWALGQIGGAAARRFLEQLVNDSEGVRREAAAEALKELQFFDDPIQSLPLDDDEDEDEYWYGDDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5D9</accession>
    <name>A9B5D9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
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    </evidence>
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    <sequence length="119" mass="13199" checksum="9E213BC00E1F1936" modified="2008-01-15" version="1">MTGIIELIAQTTGCCAPASAGLNETEAEAISADFQVFAHPVRVQLLTLLTNSTDDVCVCDLEAAVAVKQPTVSYHLKLLREAGLVSCERRGPWAYYRVERERLASLKARINRHLDTWNR</sequence>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
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</entry>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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                <person name="Martin K."/>
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                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
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                <person name="Richardson P."/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <sequence length="187" mass="19711" checksum="B7EE5EC1839251E2" modified="2008-01-15" version="1">MSDSTNQQAVLESQVRSLVELSEDDLFRKLGIQVKQAEEADAAALEVAQAEGAFAEPVGVEMGLGENLRAFGARWWAEIEPKLYNLLCASESKERSQILAQLPESKGGTAAAVVGGDSGNAAADNIATALAPLLIGLLPFNLPIIASVGATIAAKMILSSGLKTTCEMWQESIEAREEAKAKENPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Pitluck S."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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                <person name="Nett M."/>
                <person name="Domin N."/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="372"/>
            <end position="391"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="628" mass="67929" checksum="BD000375287DB732" modified="2008-01-15" version="1">MAQSARWRGWFWLGLGLICLLWPNLSHAQNADAITITIDQVGFDAQGHVANGGWYPIITTIENSGADLQAQVVVTTGFGQADLLQNVDLPGGSRKQVRLLMRANLNQTVVEIKVIDAQGKQLARNRSNVRVHDSQEILVGVFGGPASSLAGASVPGRLTTVMPLDPAQLPSTDGELFNFAAIVLQDVQPTAEQAAALERWVATGGTLIVSGGPNSAELPKELASLLPASVSRSNSSAVLTTLNGRNTPAFAQINLRVNQLQPTADASIFGVGANNEALVISRKLGMGQILVTAFNPSDLPAEVNDRLVWPVLLQPQLYRDWNVALSPWSIQIRGTDQNLPSVLGLMGILFGYILLIGPINYFILRRLDRREWAWFSIPLVVLGFVGIMYLAGGDLRTGNINVTTINIIDSQLGADQGRLSVNYGFNAGRRGAWNGSIDANLIAGNQPMQGFGDEGSGTIEQTNDGKTRLPNWQSNIGQMQTLAAIGSSAVPYNFEVKVAKANSWEGATITNRSERKVEYAILFNGEESIILPALEPGASITIDNSLDRVMQSSPYLNNNDQLTQALQLLWNAGNERTNYSGLPKNSLYTKPHITVLDTEVLNEIMVDGVAAPQKSSNIYNLYVDLEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B615</accession>
    <name>A9B615_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="3">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="5" type="ordered locus">Haur_3171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:47668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:11877"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:87830"/>
            <dbReference type="ChEBI" id="CHEBI:87832"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">2 residues (Tyr-68 and Arg-71) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sirtuin family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3171"/>
    <dbReference type="EnsemblBacteria" id="ABX05808">
        <property type="protein sequence ID" value="ABX05808"/>
        <property type="gene ID" value="Haur_3171"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3171"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_0"/>
    <dbReference type="OMA" id="SMQVYPA"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034979">
        <property type="term" value="F:NAD-dependent protein deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006476">
        <property type="term" value="P:protein deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01121">
        <property type="entry name" value="Sirtuin_ClassIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="191"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="27384" checksum="59FE015D225A5985" modified="2008-01-15" version="1">MAKFPEELLQRLRQAERIAILTGAGISAESGIPTFRDAQTGFWSRMKPEDLATPEAFERNPKLVWDWYAYRREMVDQASPNAGHYALAKMAEHVPNLTLITQNVDSLHQRAGSTNVLELHGNIGRVKCSKEHVVIEPSAWLPDEEIGVPRCPRCQALLRPDIVWFGEVLPTKTFNHAKAACIQADVVFSIGTSGLVPPAATLPVTAIEHGAYGIEVNTDQTYLSDTFECCLRGASGIILPALVKAAWPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B654</accession>
    <name>A9B654_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3629"/>
    <dbReference type="EnsemblBacteria" id="ABX06265">
        <property type="protein sequence ID" value="ABX06265"/>
        <property type="gene ID" value="Haur_3629"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3629"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077889_0_0_0"/>
    <dbReference type="OMA" id="QFTYKPT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3668-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029059">
        <property type="entry name" value="AB_hydrolase_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12695">
        <property type="entry name" value="Abhydrolase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_5" evidence="1">
        <location>
            <begin position="65"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="245" mass="25987" checksum="87F29368BFC2F8ED" modified="2008-01-15" version="1">MKLVKRLAIGLVLLLIIGVVGFVVWASNPAAAMATANEALVSDQTVTVTETDWLIFEPSAAPTTGLIFYPGARVTPAAYAPLAHELASAGYLVVIVPMPLNMAIFGSDRADAVLAAYPQIEHWALGGHSLGGAMAAKYTYEHPDTIDGLILLAAYPTASNSLAERELASSMIYASNDGLATLVDIEAARPLMPSTTRWVEIQGGNHAQFGWYGEQSGDLPATISHAEQQQQTLDAALDVLQQLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B658</accession>
    <name>A9B658_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3633"/>
    <dbReference type="EnsemblBacteria" id="ABX06269">
        <property type="protein sequence ID" value="ABX06269"/>
        <property type="gene ID" value="Haur_3633"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3633"/>
    <dbReference type="eggNOG" id="COG0816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098240_0_0_0"/>
    <dbReference type="OMA" id="PMGWTAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3672-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="158" mass="17670" checksum="8254BD0E88C5697A" modified="2008-01-15" version="1">MSERPTHGRIIALDVGNKRIGVAMCDPDRIIASGQPTLPAQPTDKAYAQLLHMITEHEVVEVVIGLPLTLRGEVGAQAKAVQAFSRGLEKRTKIPITLYDERFTSVEAERSLEAMGIKKSKHRDHVDELAAILILQDYMSSIAPPRPRYHDPDHDDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B662</accession>
    <name>A9B662_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3637"/>
    <dbReference type="EnsemblBacteria" id="ABX06273">
        <property type="protein sequence ID" value="ABX06273"/>
        <property type="gene ID" value="Haur_3637"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3637"/>
    <dbReference type="HOGENOM" id="CLU_1265497_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3676-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="218" mass="23877" checksum="66ACC4ED7C9B125F" modified="2008-01-15" version="1">MSRLNHETNEWHCKVVLFGPPTRNAVKLAAQLVTAIPLAEREVTWDTPPAEEPTLVARYRPANAALGDIKPVYMLHTLRSAGSTAADRQHVLHNTDGVILLLDLESEDQSIFAERELERFLSTYGKTIASMPVILLGASPLDDGQQARLNANSLSYFAAENATTLQRALHTLTSGLEEDSGLAGIGFDLDDFDSDGSAVDLDDIEFDDLHAYDDDDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B666</accession>
    <name>A9B666_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3641"/>
    <dbReference type="EnsemblBacteria" id="ABX06277">
        <property type="protein sequence ID" value="ABX06277"/>
        <property type="gene ID" value="Haur_3641"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3641"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_4_0"/>
    <dbReference type="OMA" id="PWDSGPV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3680-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732509" evidence="1">
        <location>
            <begin position="26"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="444" mass="47788" checksum="417706788A05C129" modified="2008-01-15" version="1">MMVRRKIHGSLISLLVLTLILAACGSDSTATTTSNTGSTNPAEVKGEITVWAWNVAAKSLEATVPSFNQKYPNVKVTVQDIGRTDVYDKLTSGLQAGGAGLPDVVAIESDRMDVYTSTFPDGLADLTSRASKYEKDFDPSKWAQSKISDKIRSIPWDSGPTGLWYRVDIFEQAGVDPKSIETWADLIAAGEKILAATDGKTKLLPVDIVADDAGFRMMTSQLGVCCYFNNDGKINLTNDKSVQALTLLKEINDKGLVANINGWDGTVAATKNGDVATVPFGVWYSGTIIDQAPDLSGKWDVMLLPAFEKGGNRAANLGGSTLAIPAATKNLDAAWLFVEHALATSEGQNIMMEKFGIWPSYQPAYSADLYSKPVAFFNNQPIWKLFADEIKNIPPATYTKDYAKGQAVLASAQAKVLSQGMDPKQALQEAAAELANQTGREIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B673</accession>
    <name>A9B673_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ABX06284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3648"/>
    <dbReference type="EnsemblBacteria" id="ABX06284">
        <property type="protein sequence ID" value="ABX06284"/>
        <property type="gene ID" value="Haur_3648"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3648"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705506_0_0_0"/>
    <dbReference type="OMA" id="AYHEISH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3687-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF1058"/>
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    </dbReference>
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        <property type="entry name" value="Papain-like_cys_pep_sf"/>
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    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3b"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <end position="35"/>
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        <location>
            <begin position="263"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="391" mass="42278" checksum="79075E4C647A5CD6" modified="2008-01-15" version="1">MPRLPILARDRRRLQIAGLLLGAGLTVPLLLWWTFPATSPAPLGATATPQIVRVGATLDEPIPADWQAPVLNPELEAQALAIPETLPLTASALLYDSISADTVFTTTIAGLVASEELNLRDGPSVDYLPMAILLNTTPLTVVGRFEGWLQVVTPQRALGWVDDSYVALASSAQTLPQVNLHADPNPVLVAGLTVERANVRSKPQTEAEIITTLSAEHGQVNLLQQREGWFNVRTNDGTEGWVSAELLQADAYILRRVPTLSASPNALEAVRLARKYVGYPYVWGGETPRGGFDCSGLVLYVYGKLGIDMPHSAAEQWTGGYGEKVASRRDLVPGDIVFFKNTYKKGVSHVGIYAGNGKVIQALSESLGIRVSDLSNSYWSSRYVGAIRPFP</sequence>
</entry>
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        <submittedName>
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        </submittedName>
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    </gene>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0171"/>
    <dbReference type="EnsemblBacteria" id="ABX02823">
        <property type="protein sequence ID" value="ABX02823"/>
        <property type="gene ID" value="Haur_0171"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0171"/>
    <dbReference type="eggNOG" id="COG2442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146679_2_0_0"/>
    <dbReference type="OMA" id="ETILYEY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-174-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="106" mass="12106" checksum="4F7265635985C741" modified="2008-01-15" version="1">MMMNIEDFFEFRADGAIRIRGHRIDLAHILPYYHDGYSPEMIGLEFPSLPLTTIYAAILYYLSNQVRVDAYMETYFASAQAAITAHEAQATSPVSQRLVMRRNQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6C4</accession>
    <name>A9B6C4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0175"/>
    <dbReference type="EnsemblBacteria" id="ABX02827">
        <property type="protein sequence ID" value="ABX02827"/>
        <property type="gene ID" value="Haur_0175"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0175"/>
    <dbReference type="eggNOG" id="COG1287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432625_0_0_0"/>
    <dbReference type="OMA" id="WGRYTLL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-178-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="632" mass="69731" checksum="B0BC02C367AEBEA1" modified="2008-01-15" version="1">MNRQRMIGLGGLLGLALLILILPNSRFWFAALVCALAPGYVLERWLDLDLAPLVRPSLWIGLSLAVWPLGYLWLTTLGLSLSTGMITLIAFGLLAGVGWRLWREGERPWALPAPVPILGLALLIVTFAISTRISHIRNVAFPPWVDSLHHATIMRVIAESGQVPYSLRPYMPVDNFGYHWGFHATAATIYNLSGMSIPQFMLWYGQFLGVLVVISVGSATIGLTKSPIAGLAAATMTGFISIMPAYYLSWGRYTLLSGLAMVPVVLLLAWVALDRPDRKGLILLTLVVGGLLPTHFVAAGFALLWCVAVWLGRDVWTEQRWQILGKQAASVGMAILLMSPWLALLIREIQPAGSGTPKQLIGGGYNTYEAAKGLYWTWNNLLLFLVGLLAAWIGLFQHWRLVLISFLWASLVMLFANPVVIGLPYLSFFNNNIVALAIFLPISLWFGFGVASLDQGLSKHLKQGVARGWRAIRTAILAITVLISATKMHSVINDGTIIAKADDLTALNWIVQRIPKNARFAINTEGWLYNVARGSDGGWWILPYAGLQVSTPPVVYNQGTAEYIAAVEAETSWLRNANEKSAAELAQWMREHNYDYAYATTNGKIFNQAKLANTAEFELVYENASVAIYLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6L9</accession>
    <name>A9B6L9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_1685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial lectin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1685"/>
    <dbReference type="EnsemblBacteria" id="ABX04328">
        <property type="protein sequence ID" value="ABX04328"/>
        <property type="gene ID" value="Haur_1685"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1685"/>
    <dbReference type="eggNOG" id="ENOG502ZAWW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150581_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1709-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040964">
        <property type="entry name" value="SBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17882">
        <property type="entry name" value="SBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SBD" evidence="4">
        <location>
            <begin position="3"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="SBD" evidence="4">
        <location>
            <begin position="69"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14379" checksum="4861E6A436602428" modified="2008-01-15" version="1">MSVYWVENQWGGDSAPWHPGGTWVLGARDNQNVVAINISSADNGQTFTGTMTYINEGPIGFRATRTSANNYAVENQWGGDSAPWHPGGHWIIGTRDNQNPVNLDVDSRDGGQTLNGTMVYAGEGPIGFRGKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R3</accession>
    <name>A9B6R3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1729"/>
    <dbReference type="EnsemblBacteria" id="ABX04372">
        <property type="protein sequence ID" value="ABX04372"/>
        <property type="gene ID" value="Haur_1729"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1729"/>
    <dbReference type="HOGENOM" id="CLU_1693092_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1756-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="155" mass="17510" checksum="31F2A631BF89C5F9" modified="2008-01-15" version="1">MVKVSIVQPANSTGELLADYDRSSKIISVYNPLPRQWAYTINVDHQLTIDLDAQGWVANIDLFAKPRLNHTIVVPYNAKRGAIQCAIPQSGERFIPNPIVVETDQARRLIRISLDPTNDPEQGQWLKTSEQVYLQINADLLRTIVIDFGTKGLWD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6X4</accession>
    <name>SECA_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="1">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">secA</name>
        <name type="ordered locus">Haur_3205</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">May bind 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B6X4"/>
    <dbReference type="SMR" id="A9B6X4"/>
    <dbReference type="STRING" id="316274.Haur_3205"/>
    <dbReference type="EnsemblBacteria" id="ABX05842">
        <property type="protein sequence ID" value="ABX05842"/>
        <property type="gene ID" value="Haur_3205"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3205"/>
    <dbReference type="eggNOG" id="COG0653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_0"/>
    <dbReference type="OMA" id="MVHYDVQ"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008564">
        <property type="term" value="F:protein-exporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000215113" description="Protein translocase subunit SecA">
        <location>
            <begin position="1"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="945"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="139"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="994"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="996"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1005"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1006"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="1032" mass="116075" checksum="0F022C16EC7FBC81" modified="2008-01-15" version="1">MFKWLGKLLGDPNAKVVKKMQPTLDEINALEPKMKALSDEQLREKTAELRTRFAELTKADREALDDRYADENRHDSTVEKDYQKELRVIEDAALDELLPEAFALVREASSRVIGQRHYDVQMIGGIVLHEGRIAEMKTGEGKTLVASLPLFLNAIAGRGAHLITVNDYLAKVGGGWMGPIFHSLGMSTGYIAHDYSAIYDPNYIDPNAKQDDSRLVHWRPCSRREAYMADMTYGTNNEYGFDYLRDNMVQHKDQCVQRELHYAIVDEVDNILIDEARTPLIISGPAQESSDNYRRFSSLVRGLKRSSISPDEVRKGLKDDFDGDYWIDEKSRSITLTESGLEVMEKRLNLPDGENMYDAKNFELTHYLENALKAEYVFHRDVDYVVQNGEVVIVDEFTGRTMPGRRWSDGLHQAVEAKEAVEVRRENVTLATITFQNYFRMYNKLGGMTGTAITEAEEFSKIYNLEVVIIPTNRQVVREDYRDHIYASQKAKYNAVLREIKEMHEVGRPVLVGTTSVESSEIVSNLLKQEGLEHYLLNAKQHEREAYIVAQAGRTGAITIATNMAGRGTDILLGGNPDGLIEEHLKALGTTITDATPEQLAQAQAQAKADVEAERKAVMEAGGLHIIGTERHEARRIDNQLRGRAGRQGDPGSSRFFISLEDELMTRFGRIDTIKRLMERMSDGDEELPLESGLLDKAIESAQTRVEGYNFDVRKHVVEYDDVVNKQREVIYADRHAILGGEDMGDRILEMVVDEIDIHVEEFLDNRELDKPDLEGFLRQLYSIVPQLKAQETELAARFKGKQADEIGEIATEVVEEAYNRLGEELATQYTTLLQRGVQPIPGVSGPEAFFAHFERQEMLGAIDREWIDYLTAVDELRQGIGNVAIAQQDPLVAFKREAFKMFDELKGNIQNRIVYNFFTDAANWQVRLRQVELEMEARLALAQTAGGSENATEDAPKPAKRGVGGAARRVSNAAGQAAPARRIVIKIGRNDPCPCDSGKKFKACHGLPGKEAELEAILAVKHTHAQAVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Y7</accession>
    <name>A9B6Y7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LmbE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3218"/>
    <dbReference type="EnsemblBacteria" id="ABX05855">
        <property type="protein sequence ID" value="ABX05855"/>
        <property type="gene ID" value="Haur_3218"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3218"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_1_0"/>
    <dbReference type="OMA" id="PLKLYYN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3253-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="33669" checksum="95BCFC2B73F7ACE0" modified="2008-01-15" version="1">MHFPRDLRAYGIESHWLNTAPMTRRLLFVYAHPDDESFGNAGTIAYYAHHGVSVHYICATRGEAGDVDPSLLQGYGDIATLRSTELGDAANAMGLAAYHFLNYRDSGMPNTPANEHPEALVQAPVEAVAAKVTAAIRAIQPQVVITFNEYGGYGHPDHIAMHHATHLAFARAGDGAWLPEQLDAGLPTWTPRKLYYSTFNPLLIKMMLRLWRLSGRDPRKGGNNGDIDFVKILEAVNPPTASVDCSSVVDQKVAAWQAHRSQLGQMGLSLKLPRLLRQRFLGREQFSRVVPQPNGYERDLFEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B742</accession>
    <name>A9B742_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3273"/>
    <dbReference type="EnsemblBacteria" id="ABX05910">
        <property type="protein sequence ID" value="ABX05910"/>
        <property type="gene ID" value="Haur_3273"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3273"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_464431_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3308-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735497" evidence="1">
        <location>
            <begin position="25"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="587" mass="62272" checksum="59A369301B7C5F86" modified="2008-01-15" version="1">MRRITFRYLALIGLLLLGSSWLPAASAETSVANLSDLATGATSSISNESINLAYNGLSYFVANDGNNGVGLWRSDGTAAGTFMLTTAAQNAISPQYLVGYGAYVYIAAHTETDGYSIWQTDGSSNSITKVVSLDPSNYSTGYVKISLMQVVQNTLYFIFSYEGQIEIWKLDQALAPVLVKKAVAFNSAWSASNIDRLVEYNGAIYFVTSTITIITYGATSDLWRTDGTAEGTYKVHSIDTRKYAQVLGPIVAGGKLIFNSFHDGVVTSDGTPTGMVRFENRIDVGEGPMQLTSVNGIGLMTYFGGERLWSTDGTVAGTYPIDVNPNGLDNVSFGPVIGKYLYFTADHANYGRELWRTDGTIAGTTLVHDGIPGVNASNPKNLAAVGNQLYFSAATAQGGVQPWKLTCAGANPTMLGLVGSNTVNADPGLFLATTQGVVFGATTPSLGHEPWLYRESGNTWLKSSTVVGTASEQVGAIPVTIGNDGTLMQQSITVTLTLTDGVEYLSDTSGITPTIQGSMLTWQLNQIPTNCSEQSFVVYVGLPDAEVGEQRPFSVTIGGMVAGDISNDNQSNGLIVVGNPLFLPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B770</accession>
    <name>A9B770_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Galactokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3717</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3717"/>
    <dbReference type="EnsemblBacteria" id="ABX06353">
        <property type="protein sequence ID" value="ABX06353"/>
        <property type="gene ID" value="Haur_3717"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3717"/>
    <dbReference type="eggNOG" id="COG0153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_2_1_0"/>
    <dbReference type="OMA" id="PVCYNLR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3759-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="9">
        <location>
            <begin position="7"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="7">
        <location>
            <begin position="100"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="8">
        <location>
            <begin position="271"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX06353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="376" mass="40403" checksum="793AF5EADE146DCF" modified="2008-01-15" version="1">MTEVKAAFFVRSPGRVNLIGEHTDYNAGFVMPLALERGTTFQVQPRDDQQLIVHALRFNAHDQADLANLAAGTHGDWRDYVRGTAQSLLDAGYALQGAEINIDGDLPLSGGLSSSASLEVGLAFSLLYAQGITIAPAELAKIAQRAEIEYAHVNCGIMDQLAIAAGVAGHATLIDCRSLEIEAVPIPAEVAVLVIDSGVPRTLAGSAYNQRRAECEQAVAILRQLDPNINDLRDVNSDLLAQAVEQDRFEEVIYRRARHVVSENERVHKAAAAFRAGDFGYVGELMNESHWSLRDDYEVSGPELDQLTELLRDMPGVWGARLTGAGFGGCCVALVEASHVDAVIVALSPAYHAATGRTCEAFSTKASALTIEEPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B781</accession>
    <name>A9B781_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3728"/>
    <dbReference type="EnsemblBacteria" id="ABX06364">
        <property type="protein sequence ID" value="ABX06364"/>
        <property type="gene ID" value="Haur_3728"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3728"/>
    <dbReference type="HOGENOM" id="CLU_2825224_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3770-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="66" mass="7559" checksum="E57A306F50A888D2" modified="2008-01-15" version="1">MQVFVHLDELLTPALLQQHQRHIVDFLEMEGITPEAEVGRTKVNERTAKELLAELAHDLDQAPENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7C5</accession>
    <name>A9B7C5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="8">FGAM synthase</shortName>
            <ecNumber evidence="8">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="8">FGAR amidotransferase II</shortName>
            <shortName evidence="8">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purL</name>
        <name evidence="12" type="ordered locus">Haur_3772</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3772"/>
    <dbReference type="EnsemblBacteria" id="ABX06408">
        <property type="protein sequence ID" value="ABX06408"/>
        <property type="gene ID" value="Haur_3772"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3772"/>
    <dbReference type="eggNOG" id="COG0046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003100_0_0_0"/>
    <dbReference type="OMA" id="FIEPYQG"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
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    <sequence length="959" mass="101903" checksum="731D663657A47C84" modified="2008-01-15" version="1">MSAYLVTVCPREADNHERLYLLAGDLSSEDVQRLTLELLHDPVAHTATWQALDAELATPKAGALVEIAFRPGVTDNEAETILVGARHIGINGLKQAKTLRRVYVSDVQDEAVLRQFAGEHLLNDLIETAYSTLEARSAERLQFYQHLLQLPAPHTPTITRVALRGVSDSELERISREGILALSLAEMQAVRDYFEDLGRDPTDGELETLAQTWSEHCRHKTFRATISYQQVAADQGIDAALHPALAELNAANGATINGLLNHYLRSATNAVSNEALLSAFVDNAGIVAFDEQYEISFKVETHNHPSALEPFGGANTGVGGVVRDVLGVSAKPIAVTDVLCFGYPDLPESELSQGVLHPRRIREGVVAGVRDYGNKLGIPNVNGAVWYDHGYTANPLVFCGTLGIAPRGSHPRGVQAGDAIVVIGGRTGRDGIHGATFSSVELTHDTAETVGAAVQIGDPVTEKTVIDVLLQARDLGLYSAITDCGAGGLSSAVGEMGEETGAVVELRDVPLKYAGLQPWEIWISEAQERMVVSVPPQNVQTLLDLCRGEDVEATVIGHFTADGVLTVKHNQLTVVELDMAFLHSGGVQFKLNADWQPSPAPASQPATIDHTALLKATLGQPIVASNENIVRTYDHEVQAATVLKPLVGVNEDGPGDAGVLQPRVDSNRGVVLGCGLNPLYGKIDPYWMALAAVDEALRNIVAAGGDPEQTWILDNFCWGDPKLPDRLAGLVRASAGCHDAALAYRTPFISGKDSLNNEYRDAEGKRVAIPPTLLISAMALVPDVLQTISMDAKAAGNAIYLVGLTHNERGGAVSALVGGIDNGNLPKVNLATAPSVHKALHAAIRANSVRACHDLSEGGLAVAAAEMAFAGGFGLSLELSAMPTSGSLSADALLWSESTTRFLVEVAPEQAANFEAQLSNIAYAKIGQVLAEPRLIINDLAGQPIIDSDLASLKAAWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E2</accession>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
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                <person name="Ivanova N."/>
                <person name="Goker M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
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    </evidence>
    <sequence length="180" mass="20341" checksum="31173A906388697F" modified="2008-01-15" version="1">MSTIAFLRAINITNHFVKMEELRDVLVAHGFSNVQTYIQSGNVVFDDPTQSYAEAEHLIATQLEDCFGFAVATFLRSAAELVELEQACPFTPSEIDPQAALYVTFVQHEPDAEAQARLAQYQNELDTFRITGRHVWWLRHKQRGESKFSGAKLERAIKQAGTARNITTIRAMIAKYGFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y0</accession>
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        <submittedName>
            <fullName evidence="4">Integrin alpha beta-propellor repeat protein</fullName>
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    <reference evidence="5" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
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                <person name="Richardson P."/>
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                <person name="Han C."/>
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                <person name="Schmutz J."/>
                <person name="Brettin T."/>
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            <dbReference type="PubMed" id="22675585"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ABX04508.1"/>
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        <property type="protein sequence ID" value="ABX04508"/>
        <property type="gene ID" value="Haur_1865"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="4"/>
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        <property type="entry name" value="FG-GAP"/>
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    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
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    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
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        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="575" mass="59979" checksum="BDAED0ACB6375084" modified="2008-01-15" version="1">MDRSGFAPRWFRRIVWMVLLVQVVVIAATISSSPTSVMATAPLSSADWAAIRTLLPLEQQAYFKPSQVSETDYFGLSVAMSGDTVVVGAPYENSSTAGVQNSATPTVDELAPESGAAYVFVRNGPTWSQQAYLKASQVSIADLFGSSVAVSGDTIVVNALYEDSSTTGVQNSATPTVDEAADSAGAAYVFVRNGTTWSQQAYLKASQVSETDFFGGTVAVSGDTIVVGAHFEDSSTAGVQNSATPTVNEAADNAGAAYVFVRNGATWSQQAYLKASQVTGLSPFEEGRFGWSVAVSGDTIVVGATYEDSTTAGVQNSATPTVDELAPESGAAYVFVRNGTTWTQQAYLKASNVSMYNYFGRSVAVSGDTIVVGAPYERSNIAGVQNSATPTVDESAFTFMAGAAYVFVRNGTQWSQQAYLKASQVSSSDGFGWSVAVSGDTVVVGIPNEDSDTAGVQQSDTPVVNEDASDSGAVVVMVRNGTTWSQQAYLKASNVSSFDVFGNAVAVAGDTVIVGAPFENGSIAGIQYGSSLVVDDDVIDAGAIYSFRLPVVDPYLMYLPFVATSDRAAAQTAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y1</accession>
    <name>A9B7Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1866</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1866"/>
    <dbReference type="EnsemblBacteria" id="ABX04509">
        <property type="protein sequence ID" value="ABX04509"/>
        <property type="gene ID" value="Haur_1866"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1866"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_5_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1895-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="536"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX04509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="812" mass="91490" checksum="D5FF4859CB7A6906" modified="2008-01-15" version="1">MSESFGYWLKQRRKELNFTQEYLAELVSCSTITIRKIESNERRPSRQIAARIAKFCQVEANRAFVDAAWAGQSPSPSDGGSPPEPAPSNLLPPFSSIIGRDSAIESICVQFQAQKARLVTIVGSPGVGKTRLAQAIGQQLLTHFSDGVFWISLDPIVNASLVPSLITRVLGIHENPNQSIEETIFNWLKNRHLLLILDNCEHIIELRQFVNQLLSYCPTLSILATSREVLHLRWEQRFPLRPLTVPVRGMQLDLAQLAQIPAIALFLERSRAINPQAELNASNARAISTICMQLEGLPLSIELIAARSAMLSPQMLVHRLNNQLNVLTQGSRDLPHRQQTLRNAIQWSIDLLDSAEQFLLVALALAPESCTLLSLEALADCYSPWPWSIFDGLTNLFDKSLIWIQQQQTDEPRFGMLRVLREYVLEQLAEPTTIQQLRQSFASYYLNIAETIYQKMLNSRTNSLFQEIAAEYYNFHTVITWCLEPPYDLENAIKLIATLIDFLHLYGYQREGISWLQHILGLIEQQTVTLSPAILADAYNALGFLYYHQGNINQAQHFFERVLELIGGHTSFKHARILYNLGLVKKNKGEFLQAEADLQASLASWRTLGLQPGEAYSLWGLGSLALDQGLYTHGLTYLQQSLAIWQTLESTHGQVMVLSDLAELALLQANPHEAEQILAQIKTIVEASNYTITSSRIALLEGKCAMQRHDFSHAQTCFEEAEEIAEEQQSTAYLAKIHLEQAKLALVQAHYHQASYHGYEGLRLATMLEHQTGIAKAHHVLAQVYQQLANPSQAEQHWQAYAAIYQHVGLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B806</accession>
    <name>A9B806_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-isopropylmalate dehydratase, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3303"/>
    <dbReference type="EnsemblBacteria" id="ABX05939">
        <property type="protein sequence ID" value="ABX05939"/>
        <property type="gene ID" value="Haur_3303"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3303"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_1_1_0"/>
    <dbReference type="OMA" id="APFMVGE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3340-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="2">
        <location>
            <begin position="48"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18175" checksum="55A900D07D96403B" modified="2008-01-15" version="1">MPRIWVFGNDVNTDQMVPGRYAPYMLGANDDVRRYAFIEARPDFAPNVQPGDLIIAGPNFGCGSSREYAPLALKRCGVGAIIAPLFARIFFRNALNLGIPCFTADLREQVADGDFVDFDLAAGLITNNANQIQLPPPEGWMREVWAEGGIVPFYRRHGRFPATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B825</accession>
    <name>A9B825_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl transferase family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3322"/>
    <dbReference type="EnsemblBacteria" id="ABX05958">
        <property type="protein sequence ID" value="ABX05958"/>
        <property type="gene ID" value="Haur_3322"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3322"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_2_4_0"/>
    <dbReference type="OMA" id="NYPFGKI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3359-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="355" mass="38321" checksum="7D8A2DA165EF9EB0" modified="2008-01-15" version="1">MRALRPCLIFIKRIHMSVSLAQIFLIFLSALTMSIVSTPLVRRLAIAVGIIDQPNARKVHTNPVPLLGGLAIYGGVVVTLLIWDDQFILRELAAILGGATIVVVCGMLDDKWGLSASLKLLGQIIACFVLIYAGIQVQLFASPWLNALITIAWVAGISNAINFLDNMDGLSAGLTAVASAFFLQLAVLNGQFLVAALSAATMGACIGFLRHNFVPTKIFMGDTGSLFLGFILAVLGIKLRFPSNSIIVTWMIPIVVLGVPIFDTSMVIVARLRRRVNPFNTPGKDHISHRFVALGSSRREAVLICYMLGVGCGITATMLSKADVQEAYALAALLIGIALVGIWLFERYARYNPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B833</accession>
    <name>A9B833_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3330"/>
    <dbReference type="EnsemblBacteria" id="ABX05966">
        <property type="protein sequence ID" value="ABX05966"/>
        <property type="gene ID" value="Haur_3330"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3330"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081551_1_0_0"/>
    <dbReference type="OMA" id="DCCRGRP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3367-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="257" mass="28846" checksum="718358D14143FB02" modified="2008-01-15" version="1">MQSLGLEPPVVLKLLSHDLRWRLLQLLVHSDYRVHECVAALQAPMNVVSYHLRLLREAALVIERRSEADGRDVYYHLDLPSLQTAYQASAQALHPDLDPFAAKTTSQAYQLSKPVRILYLCTHNSARSQLAEAITRHLGGSMLDVVSAGTQPAEVNPLVLATLEEKKISSAGLYSKTLQPYLEQDFDYVITVCDRAREQCPTLAGHPTSMHWSFADPLRETSELAQAATIETTAQQLMTRIRFLLTTIERQQREGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8K9</accession>
    <name>A9B8K9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07673">
        <property type="protein sequence ID" value="ABX07673"/>
        <property type="gene ID" value="Haur_5043"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5043"/>
    <dbReference type="HOGENOM" id="CLU_027562_39_2_0"/>
    <dbReference type="OMA" id="YACGLRI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5106-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="160" mass="18101" checksum="995480C6B768C278" modified="2008-01-15" version="1">MVIYACGLRIQEGVSLQVSHIDSARMVLHIHAGKGNKDRRVPLPLPALVRLRTHWRTHRHPIWLFPARYRDSLDQPMAQRSVARAFQVALQESGIQKPATVHTLRHSWATHLLEAGINLRIIQDWLGHRSPRTTALYTHLTPQAEAAAATTSQRLLDAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8L4</accession>
    <name>A9B8L4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07678">
        <property type="protein sequence ID" value="ABX07678"/>
        <property type="gene ID" value="Haur_5050"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5050"/>
    <dbReference type="HOGENOM" id="CLU_629726_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5112-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="143"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="435" mass="49640" checksum="711D21EAFFD7F76A" modified="2008-01-15" version="1">MVTDRWFAARRTLYELLHTNPDWSNRQFATALNVSPDWVRLWKQRIGSPPHPDPDVVCQSQSRARKTPPPAWSDRVIHRILTLRQELAAQFHRTVGAKTILAYLQRDPDLADDRIPRSPTTVNRILRDHQLLVDPPTHQRQPRTPCPPMQEIEIDFTDVTTIPTNPDGKRQHAAEAFMWVDAGTSIRVAARISTDFHMASVIRTTASILQQIGLPARIRMDCDVRLVSNKRVADFPSPFQRLLLNLGIQVDVCPPHRPDLKPFVERFHKNYKGESVYPNWPTTEAEAQVQVDAYCDWYRTERPHQGRACGNRPPAEAFPELPVLPPVPAQVDADGWLKQIDGWTFVRRVNAQGKLMLDGATYTAGIAYAGQELAVQVDAAARELVLIQRERAVKRVTLKRLLGGMMPFEQMVEALCGLAAQETKRLNQRQQRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S7</accession>
    <name>A9B8S7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07741">
        <property type="protein sequence ID" value="ABX07741"/>
        <property type="gene ID" value="Haur_5113"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5113"/>
    <dbReference type="HOGENOM" id="CLU_520513_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5175-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735381" evidence="2">
        <location>
            <begin position="26"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="523" mass="52823" checksum="75DD174118A246F6" modified="2008-01-15" version="1">MIGVRRVSAWLAAITTIVVSWPSPAAQPVPLATPVVQLVAQPSVAVPGMAVTVVVTQPAEAVTATLTLTLSPVVAWDRVVTSHNRACVISGVVATCGELDDPALPAVATLAFTVPVTATEPLVITAWRSDVPAHPMITTVLLDLTRTVTPVATATATVVVPSATATEEPAVTHALPSLVPATATDAPTATAPPTATPTSAPTATATASSTPQPTASPTSLPTALPAPLPILPTAVASDGGLPPIIVFPTLTTVPIAPVVDAPSGTTTPPVPTACVVDGQPVAVVDSQIRAGVEPCALLSLPLAVQAIPPALAHVVAEADSELRAGPGLAYVPLAHIPRGYGVTLTGRMFQGYVEVTAFRVGAAPLAGWLWSADLIVDALLTTPLPPVADPVAALPSPAATLPPMADPVGVRPTATLPVLGWRVQALPATTRTVTVQVCRGTATCGRDQGIAGLAVVVDSAAGDRVAQGWTDATGRWVVTLPMQEGLVVRVPWLGSVVALAATAERVHLPVNEAVLPPRFGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8U0</accession>
    <name>A9B8U0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07754">
        <property type="protein sequence ID" value="ABX07754"/>
        <property type="gene ID" value="Haur_5126"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5126"/>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5188-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1531" mass="168542" checksum="EFECA80383EF5D03" modified="2008-01-15" version="1">MDDRALRLALEALLDEPTLKSTHRASIERGLTDLKTQRITPDEWEYLCYLIEHYGASTPLPADPVAALIAAFQDKLPSVDPIALSTAIHALVGGDTAQLDGKSLALTIERRGQTQIANLAERNVVMGNLNQLDISVHIPIPDARFDSLMQAAFQRQTHERITNAAQQTESDRLLNLRLQGFVGRDNELAAIRAQIATVRPTGGYVLIKSEAGEGKSSIIAKLIQDAGFAQTPHHFIALTTGRDYQLSLLRAVVAQLILKHRLPVSYFPEESYSTMKGEFARILDELSKHGIQETIYLDGLDQLPPEGDRLIDLSFLPSQPPPGIVIVLGSRPDEAFKPLHHLNKAAYHLPPMSEIDAFTVWRSVQSGVADTLFHDLYTALKGNALFVYLAADTIRNQSVVDMASLIRQIEQNPKDIFGIKLERIKNRSEHRWPTIWRPMLALLVVTQEPLPMRVIGRLLGQPRAVIQDAVWVMGGLVSQGSDQRVALHHLLFREYIQAHEFDSEELHDIHQRLADWCAQDGDAIWADHRDALEQARRVYARHHYITHLALAENWPTLWRVLDAGDYGAQKTRFDPSMRLYALDLDRGRESAIKAGQSTEEHIQHLPRLWKYSLLRTSLTNRVDQWPNKVFAILATIGQTHEVLERIELLSSTRKQVQCWDTILPWCDTQQQKTMLVRLYQVAGHLSGIDEIFTLSIIAKITIMLGENEQAIGILDHALAIAHTLKTPEQCNEAIRAITKITTMLATNEHVLGILDRSFTIAQCIDHANYRSEALSVIAAAIAVHGDRGRVLTRNQMIDTSGRRNETISVIAAAIAVHGDIDYALTITQSIDNPVQYILAIAFIANILTILDKPEHVLGILDRALFIAQSIDNPEQRDKAMGAIAAVIVTHGDIDRALSIAQSIDNVWQRDSSLAEIAVVIATHGDIDRALSIAQSIDPPKGHTLTLAAIAVAIATHGNIDRALSITQSIEHTKERAETMSSVAVAAATHGDIDRAVIIAQSINSWQYSETMSSVAVAAATHGDINRALSITQSIESTKERAETMSRIAEVAVTYGQHEQALAILNMALSSITQSVNEAWQQRDEAIKAIAVAIATNGDIDRALTIAQSIDNIWERYQTLGILAEAIAGYGDIDHALTIAQSIDDPVQCTWALAAIAEVTITRGQDQQALAILNMAQTITHAIDNAKGRAMAFPAIAEVTATHGDIDHALSITQSIDGSWERNRTLAAIVEAIASHGNIDRALSIAQSIDNPEQRNKAMGAIAAVIVTRGDIDRALSIAQSIDNVWQRDSTLAEIVVVIASHGDIDRALTIAQSIDPQKERAEALAAIAEFTVTPGQRKQALEILNTTLTIFHTLDDQLGLHDEVIGAIAVAIASHGDIDRALSITQFIGNTWPRRDNTVGAIAKVAATHGDIDRALSIAQFIDNLDRRDNAVGAIAEATATRGDTDRALTIAQSIDDPTLRAQTFHVILQKAQSVIGILRILHHEWFRSLRSTDVWAMTVISTPLINEYPWLGVTMLDAEEWVNVQLKRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y0</accession>
    <name>A9B8Y0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C14 caspase catalytic subunit p20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07794">
        <property type="protein sequence ID" value="ABX07794"/>
        <property type="gene ID" value="Haur_5166"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5166"/>
    <dbReference type="HOGENOM" id="CLU_003004_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5228-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1494" mass="165560" checksum="16FD6B7393A765C4" modified="2008-01-15" version="1">MILPPRSPLPGLRHAIVIGANGSIASGLAPLIAPEAHDAPRMAAVLASPACGFHVQPFLGDQALMQPIRDAIETQMRAGTIGDSLIIYFSGHGTITQTAEGPDVVLVTTDTTLETIQDDPLICLRVGWLKTVLRGNTQMYPIGHVVVILDCCSSGIIDQLGNQPQMGDMPAFRRMLVSTYTSHPAYEWNRTSLYTYHLLNALEGQAVDSFGAVTMERVHQYCSEKLAGTEQRCGLGGWDYTGRWQFAWYDLQHPKLIHAAHHVESDRLLNLRLEGFVGRVTELADIHEHIAAIRPTGGYVVIKALAGEGKSSIIAKLIQDAGIAQTPHHFIALTTGRTYQLELLHTVVAQLILKHNLSRAFGLGDHVQLLKGEFFRLLDYLSKQGIEETIYLDGLDQLQPDIDGSRDLSFLPPQPPPGIVIVLGSRPDETLIPFKEKGLYCIEYDLRPLGKSDALALWRSVQPGVADDLFHDLYDALKGNALFVRLAADTMRDQSMADTASLIKQIKRNPNDLFGITLGRIKGRSLADWRAIWKPMLAFLLVAQEPLHLDVLGDLLGHDHDTMQDATLVLGGLVSQGIDQRVALHHLLFRDYLAASVFNDREVKRWQQRLADWCAVDLNTIWADDRDPIEQARRVYARHHYVTHLSLAENWPALWQVLDSDDYGEQKTRFDPSTRLYALDLDRGRESAINAGKSIDEHIQNLPRLWKYSLLRTSLTSRVDQWPDEAFEVLAMLGRTHEALERIELISDVMRQIRLWGKVIQWCDEQQQIITLRMRQCLRVIGGNHAALIEIIRIIATIGDIGQALTIAHTVQDNQQQAEAYTTIASIINTTEDSIPLLEQATFLGQAIHNPLLRAHTLATVINAFATVNAIDHALALAYSIDIDRIRTKVLAGIAQTVAARGDQNSAELLIGQAINISDTLKKDSSRSTVLIAIAKAIVATGNVDYALTIINNIDTNGSQELAREHIALTASEYEFFDHAIRLTESISDNWRRNKTFSSIALIAAKKGFFDQAIAITQYTSSYKQVETLAYIAEAAARLNNYDYAKTLSEKVFSVVQTMSDEKHRAEALIILARTAAILKDHNRAIMILKQTLLNKYNQDDRYRDESLRAIADVYITVNDLNQAITIAQTLTRNVDRDSLLSVIAKAFALDGNINQAHIIAGSIKSVWSRSHTVASIAKATAMMGNIEDAVTQAQSIQEVDAQVTALSAISQILSSKGNQQKARSLRKQAIQTSRLITESDSHDKAIMAIAQLYAVSHYFDHAISIIKGINNIWTCTETLISIAQIALTSDKVQEALLIFNQACLIVKSRTSDIVLAEVLSVIGQATARAGFIEQAILITQDIEDHGKKSKTLSIIAQAMAAAGDYKQAQSLVKEAISLTLFITELDDRLEALVAIIVTLAVSGDLGTAIHLAQLIPDLWNRTKALTSILEAHSYNNEVAIDVIQWEWLMGVTNSDMWNLLLLSTPLLKTNLCMGIVLLEGEQWVQEQLIRIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B935</accession>
    <name>A9B935_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase Tn3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_5222</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="7 8">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="8">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="7 8">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07849">
        <property type="protein sequence ID" value="ABX07849"/>
        <property type="gene ID" value="Haur_5222"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5222"/>
    <dbReference type="HOGENOM" id="CLU_009098_2_2_0"/>
    <dbReference type="OMA" id="VGEQHGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5284-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002513">
        <property type="entry name" value="Tn3_Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01526">
        <property type="entry name" value="DDE_Tnp_Tn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0614">Plasmid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DDE_Tnp_Tn3" evidence="6">
        <location>
            <begin position="6"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="47696" checksum="A41887CF01F79185" modified="2008-01-15" version="1">MISLLDMLKETDLRVGVTTDFHTSTAREHLDRATLQRRLLLCCYGLGTNIGLKRVCAGSPGDQHKDLAYVRRRFLLRDQLRNGIAKVVNALFDARLPQIWGEGTTACASDSKLFGAWDQNLMTDWHPRHRAAGVKIYWHVDKKAACIYSQLKHPFASEVAAMMEGLLHHNTTMTVERNYVDTHGQSEIAFGFCHVLGFTLMPRFKAIHRQKLYRPERGNRTAYPNLQPVLQRPINWERIRREYDQIIKYATALRLRTAETDAILRRFSRRNFQHPTFKALLELGRAIKTIFLCQYLHSEDMRREIHEGLQVVENWNGTNDFIFYGKGRAFNTNQRADMEVSMLCLHLLQVSMVYINTLLIQEVLREPAWANRLTPDDLRALTPLIYSHVNPFGVFLLDLSQRLPLKPMRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B937</accession>
    <name>A9B937_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07851">
        <property type="protein sequence ID" value="ABX07851"/>
        <property type="gene ID" value="Haur_5224"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5224"/>
    <dbReference type="HOGENOM" id="CLU_2436776_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5286-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="90" mass="10183" checksum="EAB4B6699F88808C" modified="2008-01-15" version="1">MDSSQTLQFTSSLTDRPLEWRIKFDPLVWDATAQGIPIVSDGVMQADPPATIRLIPRAHGITTMRIDLSYRLCPGCDTMLDETRYEITIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B989</accession>
    <name>A9B989_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction modification system DNA specificity domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_5276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="5 6">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="6">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="5 6">pHAU02</plasmid>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5276"/>
    <dbReference type="REBASE" id="16924">
        <property type="entry name" value="S.HauORF5277P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07903">
        <property type="protein sequence ID" value="ABX07903"/>
        <property type="gene ID" value="Haur_5276"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5276"/>
    <dbReference type="eggNOG" id="COG0732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021095_10_2_0"/>
    <dbReference type="OMA" id="MLAIDAC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5338-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0614">Plasmid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="15"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="226"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="418" mass="47765" checksum="D81BB0B02D1ABB9D" modified="2008-01-15" version="1">MKIEDTTTSSIWDLPSHWGVKKLKLIAKEISQQIKPADNPSTVYNYWGLDAITKGQFQEPKQNLVKGSNIESTCVTFTENQIIYSKLRPYLNKVIVPSIPGIGTTEWIVVEPDANVVDRKYLAYVLRSPAFLRYVSRGENINGARMPRLRKDSFWNFPIPLPSLSNPARSLQIQQSIVVRIESLLSELGEIRELHRRIDLDVSNVMDSIFRDVYIDLENKYPSRQRIDSFTQVKTGGTPSRKHSEYYNGDIPWVKTGELKDGLIKKTEEYITLEAMQNSNAKKIPIGTLLVAMYGQGQTRGRTGLLAIEATTNQACCAILPNPYIFIPRYLQFWFIFMYHDLRKKSDARGGNQANLNSQIIKELKPPLPPIFVQQQVVSYLDAAYNELIDMQSIQSINKLLFDQIEQSILEQAFRGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AU93</accession>
    <name>A9AU93_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,5-didehydrogluconate reductase</fullName>
            <ecNumber evidence="5">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0361</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.274" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0361"/>
    <dbReference type="EnsemblBacteria" id="ABX03012">
        <property type="protein sequence ID" value="ABX03012"/>
        <property type="gene ID" value="Haur_0361"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0361"/>
    <dbReference type="eggNOG" id="COG0656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_0"/>
    <dbReference type="OMA" id="WRHPDEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-364-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="27"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="286" mass="31847" checksum="A531A9EBC8C1CC8C" modified="2008-01-15" version="1">MTIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGAAIARSGVAREDLFVTTKLWIQDTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAWRAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQIETHPFQQQIDTQQFLQQQGVQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEENFNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUC8</accession>
    <name>A9AUC8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0396"/>
    <dbReference type="EnsemblBacteria" id="ABX03047">
        <property type="protein sequence ID" value="ABX03047"/>
        <property type="gene ID" value="Haur_0396"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0396"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_0"/>
    <dbReference type="OMA" id="IEGPCHH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-399-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="300" mass="33242" checksum="C480B687E3E044C9" modified="2008-01-15" version="1">MLDLQKLRMFVAAAQSRNFTRAAEQLDLTQPTVSQQIQTLERELGVSLFERLSRGIELTAAGRALLPHAEQMIALERIAEQAVRAAAGQSERTLLLGVGNTLATYALPDLLQRFNWEHPAFVVHIGTGNTEQLLAQVISGEFELALVGSPIVHTQLIIMPFLTTELVVIVSPDDPWARLKQINIEALHGRRMLLREEGSALQASVSELLNAQQIRPKQPIVLGNLEAIKRSVEVGLGIALVPAMAVRREVAAGRLRQIHLANVPTRRVYNVVHHRDRHITNAAQLFLDLLRKPLGPDTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUF9</accession>
    <name>A9AUF9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0427"/>
    <dbReference type="EnsemblBacteria" id="ABX03078">
        <property type="protein sequence ID" value="ABX03078"/>
        <property type="gene ID" value="Haur_0427"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0427"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-433-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="35452" checksum="2DCA4F9BED7E57F4" modified="2008-01-15" version="1">MSELAIQTVDLLRRYGKYTAVNKLNLKITLGSIFGFLGPNGAGKTTTLRMLAGLLEPSSGQVFLHGQLIQKTSTAAAIVGYMPDFFGVYDDLRVWEYLDFYARCHGIEPAKRKSTVDGLLDLVDLSEKRNAFVQHLSRGMQQRLCLAHALVHDPKILLLDEPASGLDPQARVELRELLRTLRDMGKTIILSSHILNELEDICTDFGIMARGELLAQGSLETLRQRSRPALQIKVLDDLDRAMRLIAAQSGVLRVLEPAEATPMLIEVEFDGDEQQASQLLLNLARAELPIADFHREDDSLERLFLQLVNNHGLEERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUH8</accession>
    <name>A9AUH8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0446"/>
    <dbReference type="EnsemblBacteria" id="ABX03097">
        <property type="protein sequence ID" value="ABX03097"/>
        <property type="gene ID" value="Haur_0446"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0446"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_0"/>
    <dbReference type="OMA" id="GYGTMQL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-452-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="18"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="283" mass="31217" checksum="3031DE0C51B1B9C0" modified="2008-01-15" version="1">MSLGSLTFRLGGDLEIRRLGFGAMRITGDGIWGEPSDREQSKAVLRRAVELGVNFIDTADSYGPDVSECLIGEALHPYSADMVIATKGGLLRGGPNIWYSNGRPEHLRISLEKSLRQLKLERIDLYQLHRIDAQVPLEESLGALSDLRNEGKIRHIGLSEVNNEQLAQAQKVVPIVSVQNRYSIGDHEWESMVDACEAQNIAFIPWFPLAAGRLTAPGGTLDQIAKKYEASVGQIALAWLLKRSPVILPIPGTSKVKHLEENMGAEKIALSDEDFQTLRELQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUI2</accession>
    <name>A9AUI2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0450"/>
    <dbReference type="EnsemblBacteria" id="ABX03101">
        <property type="protein sequence ID" value="ABX03101"/>
        <property type="gene ID" value="Haur_0450"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0450"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105860_0_0_0"/>
    <dbReference type="OMA" id="ECFIANS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-456-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="153" mass="16997" checksum="C15E17F51C3F68F7" modified="2008-01-15" version="1">MAKYTVTIEWERQAATFSDGKYSRAHRWIFDGGQVVKGSSSPHVVPLPYSDEQAVDPEEAFIAALSSCHMLWFLSIVAEAGLVVEHYQDQASGKMGKNSTGKIAMTKVTLRPNIIWAEPAPSSEQIEQFHHQAHEQCFIANSVLTQISIEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV16</accession>
    <name>A9AV16_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_3972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3972"/>
    <dbReference type="EnsemblBacteria" id="ABX06604">
        <property type="protein sequence ID" value="ABX06604"/>
        <property type="gene ID" value="Haur_3972"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3972"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_4_0"/>
    <dbReference type="OMA" id="AFEWVER"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4014-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX06604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1126" mass="123724" checksum="FEF7082593A3278B" modified="2008-01-15" version="1">MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLWFLQQLDPANAAFNGLRPMMIAGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQDLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMGQAPMMRLTLISLDAAEHALLLSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEAQLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFMALLSAFKTLLFYYTNQPESIVGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVLKQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAMFVLQNVPKPGDAAEPSALVIREWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAVSSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGKERLTYGELNRRANQLSHYLRTSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPTYPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEALGNLDAYPPDDPPARATAASPAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLIRALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMRLLIAGSDTWYGEEYARVARLCGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIGRPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRRPGLTAERFVPDPFAGEPGARMYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQLGHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPDLGRSEMSAAYEAPGSLIEETLAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEAFELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQQLIEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV45</accession>
    <name>A9AV45_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0472"/>
    <dbReference type="EnsemblBacteria" id="ABX03123">
        <property type="protein sequence ID" value="ABX03123"/>
        <property type="gene ID" value="Haur_0472"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0472"/>
    <dbReference type="HOGENOM" id="CLU_2649496_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-478-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734352" evidence="2">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="7612" checksum="4F8D85484CE7DEE7" modified="2008-01-15" version="1">MRKQILASLLVLAILAGCSTTGSAPTTAPVVSQPTSAAPAATPATYPTPAEGNVVVEPTLEPAQYPVPQAYPAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA3</accession>
    <name>A9AVA3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0533"/>
    <dbReference type="EnsemblBacteria" id="ABX03181">
        <property type="protein sequence ID" value="ABX03181"/>
        <property type="gene ID" value="Haur_0533"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0533"/>
    <dbReference type="HOGENOM" id="CLU_1852448_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-542-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15103" checksum="B1EC5E6D7DB906E9" modified="2008-01-15" version="1">MEVEVTVKGIIVFDEAGVYGEYEEVEIETKAVWIPGFGLLVNANIGIGGHYPLLHCAGFDSTTHAEAVRTAVAYSDAVIHHLTKHEAMVKTIDTYMSAKKAFYAQGGTNAKLEGAFLDSQEPLDQVWATFTFTPEAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVC5</accession>
    <name>A9AVC5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail Collar domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1973"/>
    <dbReference type="EnsemblBacteria" id="ABX04616">
        <property type="protein sequence ID" value="ABX04616"/>
        <property type="gene ID" value="Haur_1973"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1973"/>
    <dbReference type="eggNOG" id="COG4675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331146_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2002-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="934" mass="98711" checksum="82923C399F67A8E2" modified="2008-01-15" version="1">MTTIDDGLIVYLQLDALSAGQTVLDISGNNNNAIAHGSLQLVSDDVFGSVLDFDGNGYLELNPASIPAGNAITVSFWACGAENLPGAGVSAIAALTAADERSLNVHLPWSDGQVYFDCGAEGNTWDRMNQAANASDYKGSWTYWAFTKDVATGTMQIYANGTLWAQATGKTLPIKAVSQATFGAYSPNTAPYYGKLSSLRIYNRALSGDEILQVMAADPAAAATFDSLYPVGFNLLDDDGHATMYIDDNPQGYNLFLTISNNSPRTINLVAPNDQTPSASNHHFVLNFRPGTLSTATLSQVKLTDQTWQLSTGQAVDGTTSLYLLSTQARSLTPNQSLNLALQSISASASSGARNTRVELSYQQLQYANSLTPLIGSRLQNMVVLNAQGAHTPPLHVGFVGPNMVLNNGTTANQLTLHITNLLDDAALALSPSTSNSPTTFIVAFDSQDNQNNRDWALGTTSQVNAIAITLDNWTGGKDPESAEWIFTTTQTSLAAEAFIQMNLSNIVSSLPSGAANLYLLYENLPGYRDGYFVVAIEKTPLIITSNQRVGVGTNAPTRPLAIRGSGAGEEAISFENSSGTTKWHINQKVTTQGGFNIAETGVKDGRLFLQTGGNTGIGTVTPRTGLDTGTGVLSGAANDYTKAQFAFTGGGRVTWNGINNRLKWSQRFIAISMERSVSFAGGHVNVIQPTSDLPAAQVYDNQVRSCTADGIVLKAWEALYAVHTVGGNENAVSYQITCYTTASFFVPSNWLLVAVVNGDDGTVRLANGLVLNPGASSLNGSSIPSGTINMWSGADNALPGGWLLCNGQNGTPDLRNRFVVGAGAAYPVGTTGGADSVTLAVNQMPSHNHAASTSNDGQHNHTLYFDTGGGGNGPGGDMAKTNDGLQKNVIANFSVKTDKDGNHSHSVTIQNNGGNQAHENRPPFYALCYIMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVD2</accession>
    <name>A9AVD2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">META domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1980"/>
    <dbReference type="EnsemblBacteria" id="ABX04623">
        <property type="protein sequence ID" value="ABX04623"/>
        <property type="gene ID" value="Haur_1980"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1980"/>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075808_3_2_0"/>
    <dbReference type="OMA" id="TIWNCES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2009-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731660" description="META domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="38"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="149" mass="15351" checksum="CA9F652611359142" modified="2008-01-15" version="1">MRHILSIAIAALLIVGCGNQAASTSQPTNTPSIIVDPAELIGSRWNVLTINGQPIIGPNPLPLTIDSASQVSGNGGCNGYGGGITIDGSKLTIGPLVSTLMACAEADLQAQEGSLLQSLEKVRSYQQTETTLSLLDDQGTVVVTLARQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVH1</accession>
    <name>A9AVH1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2019"/>
    <dbReference type="EnsemblBacteria" id="ABX04662">
        <property type="protein sequence ID" value="ABX04662"/>
        <property type="gene ID" value="Haur_2019"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2019"/>
    <dbReference type="eggNOG" id="ENOG5033FMM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133158_0_0_0"/>
    <dbReference type="OMA" id="MTYFPDL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2048-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="163" mass="17877" checksum="47652CF55F291DD4" modified="2008-01-15" version="1">MMTWYDDLTPCTYFDLDQPHGDKLLAVGWLERGHPYPKGSIASAVQTKLVSLCENPWEPLAFLGWHACDRCLPDGQPDALHADGMTVPMGSENLFVPGHGLLYVAPSLIVHFIAVHGYQPPPAFCAAVLACPPMGSEDYLQAISSNGPTTFAKWVRETPRKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL3</accession>
    <name>A9AVL3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3981"/>
    <dbReference type="EnsemblBacteria" id="ABX06613">
        <property type="protein sequence ID" value="ABX06613"/>
        <property type="gene ID" value="Haur_3981"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3981"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081790_1_0_0"/>
    <dbReference type="OMA" id="PCFDDFY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4023-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="54"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="235" mass="26001" checksum="86E7209BAD1C2E67" modified="2008-01-15" version="1">MAKSTVETIRARFDADVERFSNLETGQSATVDAPLAMTLVAQAAAATTPNARHVLDIGCGAGNYSLRVLQELPNLDVTLIDLSSSMLERAQQRVGAATTGKVTALQGDVRQLELGSEQVDIIVAAAVFHHLRDDAEWQAVFAQCYAALRPGGSLWIFDLVEHSSEAVHSLMWQRYGQYLSDFRDEAYRNQVFEYIEIEDSPRPLLWQIDVLRSVGFQKLDILHKNSCFAAFGGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVQ1</accession>
    <name>A9AVQ1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SNARE associated Golgi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4019"/>
    <dbReference type="EnsemblBacteria" id="ABX06651">
        <property type="protein sequence ID" value="ABX06651"/>
        <property type="gene ID" value="Haur_4019"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4019"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1560838_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4061-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="171" mass="18727" checksum="DBB4552CED57A107" modified="2008-01-15" version="1">MWDSIVQAFNSAVIQLEANVYWLTLSYLLFSEFGAPLPIPGNFVLVAGGFLLGRQGDLPIWLMGLAILALVPGAVTMFWIGRRGGLPLLNRIGPKIGLSQRRRDRIVGWLERRAVLGLIVIRILPTFRLGTTLIPGALGMPWPRFALGMGCGLVAWVITYMGLGYAMGLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR7</accession>
    <name>A9AVR7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4035"/>
    <dbReference type="EnsemblBacteria" id="ABX06667">
        <property type="protein sequence ID" value="ABX06667"/>
        <property type="gene ID" value="Haur_4035"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4035"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_0"/>
    <dbReference type="OMA" id="FRQSTKM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4078-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="93"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX06667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="298" mass="32794" checksum="8F5B2B7A8B797A60" modified="2008-01-15" version="1">MSSNSLVSEPSMAQPKASPKALRPSRWLTPLLVHAVLGSYTLLAIAPVVLVVMNSFKGSQAIFQQPYSLPVGANFDPVGYTTVFEQTAIFRYLGNSLMVTLGSILLILLFGAMTAFGLTEYRFRGRGFLTLYALIGLMIPIRLATVSILKLMVTLNLQDTIWSLIMVYSAQGLPMAIFVLSQYMRQVPTDLKDAARLDGANEYQVFWLVLPLMRPALATLAIFVMLPIWNDLWFPLVLAPGEASRTLTLGAQQFLGQFQTDWSALLAMLTLAIAPVLVLYLIFSRQLIRGLTAGTVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW16</accession>
    <name>A9AW16_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multi-sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0606"/>
    <dbReference type="EnsemblBacteria" id="ABX03254">
        <property type="protein sequence ID" value="ABX03254"/>
        <property type="gene ID" value="Haur_0606"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0606"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_0"/>
    <dbReference type="OMA" id="IPWATHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-615-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="241"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="545"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="785" mass="88727" checksum="8B55B2B487363E49" modified="2008-01-15" version="1">MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVDLATKVIFAKTQYLGIATPPVAWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEWHHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAAGTLILLQALVLSSSLYQNQIIALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHILMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEHLRWEYTLHRDEKKLVLDVQLSPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLVEVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQHQMVTHSILAREKATRIEQQNLVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGILMLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKSQFLANMSHELRTPLTAIIGYADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDLSKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLMIDQTYHNLMFWTDISKLRRVLINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADASTTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDGPPYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW48</accession>
    <name>A9AW48_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0638"/>
    <dbReference type="EnsemblBacteria" id="ABX03286">
        <property type="protein sequence ID" value="ABX03286"/>
        <property type="gene ID" value="Haur_0638"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0638"/>
    <dbReference type="HOGENOM" id="CLU_1203502_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-647-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="230" mass="26264" checksum="9C9F1905178E2F11" modified="2008-01-15" version="1">MQTTISWRITWILLGLFVAIVGLAAYPLLQHQPQSQVFRRTTRVQIDSSLAAEAVMWGMDAYLFPDYGGVVTHTTTINNVTTTRTFTRQQDYYGVVFHNTLQAGREYVALVGQPIEQGGIKRINFYRIEYAIGEEQLQFLPYPYRGVKIYTGLEVGYEVCHYNQPTCEPIVMTDFLTAEPSPARKKALSHKFFSEEVIRHMRHDFTSALINAGPGSFFEQDEWLGALPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW87</accession>
    <name>A9AW87_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2097"/>
    <dbReference type="EnsemblBacteria" id="ABX04737">
        <property type="protein sequence ID" value="ABX04737"/>
        <property type="gene ID" value="Haur_2097"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2097"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="DKHICTC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2125-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="224" mass="24062" checksum="6974BD6761ABDDF5" modified="2008-01-15" version="1">MTMLWTEATAISAQPARLIIEQLVCRYGATCVVDHVDLALNPGDHVALIGGNGSGKSTVLRAIMGFHPISSGTLVLDQQTIHPRTKRANQYRHIAWMPQRQTLGHFPLRVRELLERSGNVRLAIQAAAHLAVDQLMDRPMQTLSGGQIQRIFLARAIGSLGAGAGLLLADEPTAALDFAGQTVVADVLASLPVTMLVVTHDRAVVARCQRVLEMAGGSLRELAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWB9</accession>
    <name>A9AWB9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2129"/>
    <dbReference type="EnsemblBacteria" id="ABX04769">
        <property type="protein sequence ID" value="ABX04769"/>
        <property type="gene ID" value="Haur_2129"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2129"/>
    <dbReference type="HOGENOM" id="CLU_1862426_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2157-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="137" mass="15604" checksum="8545F3D5371FF554" modified="2008-01-15" version="1">MALSLQLFWYQNIKAIASQSDAYGLMQFDGTTLEVLREQRWVGPEVTGTELRFKSASLSANNDLLWHANRLSLIDGTTWEVREILPYKPGFTETSNINPDGSSYAIGRSNDAVVVDRASNRAWSLRREREIRLLNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWH0</accession>
    <name>A9AWH0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4097"/>
    <dbReference type="EnsemblBacteria" id="ABX06729">
        <property type="protein sequence ID" value="ABX06729"/>
        <property type="gene ID" value="Haur_4097"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4097"/>
    <dbReference type="eggNOG" id="COG1058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_9_3_0"/>
    <dbReference type="OMA" id="PGVPYEM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4143-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041424">
        <property type="entry name" value="CinA_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18146">
        <property type="entry name" value="CinA_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="2">
        <location>
            <begin position="4"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="392" mass="42153" checksum="BE7D104DBB7B9E67" modified="2008-01-15" version="1">MQAELIAIGTELTLGTTVDTNSAWLARTLATVGVEVQRVTLVADDIGAITEVIAAAWQRSPLVLCTGGLGPTADDLTREAVAQATQRPLEFHQDLFDGIAARFRSFGRTMSESNRQQAFVPMGARPVPNARGTAPSFIIDEGSRALMVFPGVPSEMKFLVETELLPFLRNERGLKSVLLVRSIWLSGTSEAEAGEIIADLMQASYPTVGISAKAAQYEVRISAQGEDPAQVEADIEACAAEVERRLERFLMDRDGLAAHVLRRLTNRSASVAIYEGLRGAPIFNALRSAKPDLVQALRGVTIHPLDQAVDREAAESLAIAGANTVRNNWQASYGIAAVPAQVGADGFTDVCIVLVGKDLQRSFTRRVELKSDDALGFIATAALDLIRRSLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWS8</accession>
    <name>A9AWS8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0681"/>
    <dbReference type="EnsemblBacteria" id="ABX03329">
        <property type="protein sequence ID" value="ABX03329"/>
        <property type="gene ID" value="Haur_0681"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0681"/>
    <dbReference type="eggNOG" id="COG3593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028862_0_0_0"/>
    <dbReference type="OMA" id="NCTIWVE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-693-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="34"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="619" mass="71681" checksum="45185846D1D28EC3" modified="2008-01-15" version="1">MQQIETLYLPDSVKSSYQNVENQPLTQLDSLSRVNILVGANNSGKSRFMCLLTETANFSIRIRDVDFINRTIENAIDKIINIYTFIGHPQISRYDTSFLTQLKSKLITKNNTNTNNNYQNIFDVFNHLSEYKSIYEQLKEIKNISKEIVEILKSTQLNLTKNIYIPTLRGLRPLNNAYNDFYKQQTLESYFKDAEHKPEVFTGLGLYTELRSYLLGDNAKRKKIKEYQEFISRSLFEGQEVTLIPSEEQKIVVVKIGNELERPIHELGDGIQSAIILTFLPFVSLENCIFFIEEPELFLHPSMQRKILEFYHSLGRHLFFMTTHSNHLLDITIDIPEISIYSFRKSITSSDDDQTPQFVVENVDNNQSSSLELLGVRNSSVLLVNATIWVEGITDRWYLREMLQMYMKTLPNPKPKLEEDIHYAFVEYGGGNITNFSFFEEQDNEKLINIKNLCAKAILVIDHDGESKKNRKQQLKDKLGTDLIILPCREIENSLPPEVIRSVVIEYETSTQKPNPEINSFAYTDYQNESLGDFIENYVIKGEKHRRGSYKADSGTITDKLGFCKRALKYINPLTDAELAKLDTEERQLRHLELFKALPESTQQIIIKIYDFIAKLNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX75</accession>
    <name>A9AX75_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_2243</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2243"/>
    <dbReference type="EnsemblBacteria" id="ABX04883">
        <property type="protein sequence ID" value="ABX04883"/>
        <property type="gene ID" value="Haur_2243"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2243"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_2_0"/>
    <dbReference type="OMA" id="FLINIAM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2271-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX04883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="47300" checksum="8195921BD5322446" modified="2008-01-15" version="1">MDTLTAARAQMEVSLAFHMVFAALGIGFPLLMVISEGLGLKTGQAHYLALAKKWAKATALTFAIGAVSGTALAFELGLLWPTFMGFAGSIIGSAFTLEGFAFFIEAIFLGLYLYGWKRLSPLAHWLTGIPVAISGMLSGALVVAANAWMQTPVGFDLVDGKAVNVNPLAPFLSPAWLDMALHSTLSCYIATGFAVAGVYAMGLLKGRNDHYHRSALTISLGLATVTALLQPISGHISAQRVAKDQPAKLAAMEALFETQAGAPLLIGGIPDPETGEIHFGIEIPKALSFMATNDFNAELRGLNSFPPDERPNVVITHIAFQVMVGAGFALIGLGLWFWWRRWRGNLALSRKLLWALVFGSPLGFIALQAGWIVTEVGRQPWIIYGVMRTRDAVTTVAGVPQVFYLFSLLYIGLASVLVYLLRQLATGYPAETSESEATHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXM1</accession>
    <name>A9AXM1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0787"/>
    <dbReference type="EnsemblBacteria" id="ABX03435">
        <property type="protein sequence ID" value="ABX03435"/>
        <property type="gene ID" value="Haur_0787"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0787"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_380267_0_0_0"/>
    <dbReference type="OMA" id="WRAMMAQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-799-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="297"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="644"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="728" mass="81709" checksum="E8E7C7795FA04E52" modified="2008-01-15" version="1">MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPTELHYVLLHKPSSVMTTLHDPEGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTFRLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKTAPAWIELLNETADGTWVRVVIHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSKAWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSIEEERSTDRPRRRPEPRREGGFSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDRGPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRGPRREGGDFGDRGPRREGGGFGERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGDGPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPRREGGGFGERGPRREGGGFGDRGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRREEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGSFDRRGFDNRGRDDRRGFDNRGRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLKKAGGDEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXQ3</accession>
    <name>A9AXQ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal transduction histidine kinase, nitrogen specific, NtrB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0819"/>
    <dbReference type="EnsemblBacteria" id="ABX03467">
        <property type="protein sequence ID" value="ABX03467"/>
        <property type="gene ID" value="Haur_0819"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0819"/>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_71_0"/>
    <dbReference type="OMA" id="FDLCFFD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-833-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="185"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="393" mass="43123" checksum="1C197EAD8828DD55" modified="2008-01-15" version="1">MLSREQLETENASLKREVELLRHQLATQPAEPLFQSLLEAAPDGVVIVNAHGIISVVNAQAEAIFGYDRESMVGQPIELLIPERVRGVHVAYRSNYTREPRTRPMGIGSDLLARRSDGTEFYTEISLSPLKTADQLLIIAVVRDVTEQKKLAKEHEHRLTQRVSAAEAALLQGARLAAVGQLSASIAHEINNPLYAARNALLLLEEDLPEEVRESTVMQLARDQLTRIAGIIERMRDFYRPMRGEMAPTDLNAVIEETLALAGLHARHNNTMITFTPDIHLPAVVCNADQLRQVFLNLVLNALDAMTNGGTLTVTTEAATSFVTIEICDTGTGIPDDIRAHLFEPFFTNKPNGTGLGLPISAHIVTQHGGQIEVDSTVGVGSTFRVVLPYQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXR6</accession>
    <name>A9AXR6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intracellular protease, PfpI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0832"/>
    <dbReference type="MEROPS" id="C56.001"/>
    <dbReference type="EnsemblBacteria" id="ABX03480">
        <property type="protein sequence ID" value="ABX03480"/>
        <property type="gene ID" value="Haur_0832"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0832"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_4_0"/>
    <dbReference type="OMA" id="YAWMREF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-846-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01382">
        <property type="entry name" value="PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="8"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="186" mass="20302" checksum="E5DC66757A9EE970" modified="2008-01-15" version="1">MSQHLNGKRVAIIATDGFEQSELEEPKAALEQAGAKTHVISLKAGTIRGWKEQDWGSEVAVDYTLEQVNPADYDGLLLPGGVMNPDKLRRETSVLNFVRAMAEAGKPIAAICHGPWTLIDAGIAKGRMLTSYPTLQNDLKNAGAEWVDREVVVDNGLVTSRNPQDIPAFNRKFIEELGEGLHKQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXY3</accession>
    <name>A9AXY3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 10">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Haur_2309</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 10"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2309"/>
    <dbReference type="EnsemblBacteria" id="ABX04949">
        <property type="protein sequence ID" value="ABX04949"/>
        <property type="gene ID" value="Haur_2309"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2309"/>
    <dbReference type="eggNOG" id="COG0029">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_3_0_0"/>
    <dbReference type="OMA" id="HCVQWLI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2337-MON"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="11">
        <location>
            <begin position="3"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="12">
        <location>
            <begin position="417"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ABX04949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="507" mass="54057" checksum="362F132355F44285" modified="2008-01-15" version="1">MNDYIIVGSGIAGLYTAQLAAQHNLKIVLVTKEAVEECNTRYAQGGIAAAIGEHDSPELHIEDTLVAGAGISDPAAVRVLCEEGPARVHELINLGVPFDTHDGAIALTREAAHSERRILHAGGDATGAAIETTLAGVVANTNVDVRAWTLATEIMLENGQAVGVRTLDARTGERGEVRAKRIVLATGGAGQLFQATTNPTVATGDGVALAYRAGAGVSNMEFFQFHPTALRLAGAPGFLISEAVRGEGGFLRNVAGERFMLKLHPDAELAPRDVVARGIAAEMVSTDADHVYLDVTHLPADLVLLRFPTIAKVCRSHGLDITKEPIPVAPAAHYMTGGVVTDLHGRTSVPNLFAVGEVSMTGVHGANRLASNSLLEVLVWAKRVIEAPDGPIEAPTFPQTTQAITMAAEADDTPFSRAALQRLMWRNVGIVREADGLGSALRQLVAWRDAQAEPATVREYEDANLLVTATLLTYAALLREESRGAHARRDFTETREVWQRYLVLKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYA5</accession>
    <name>A9AYA5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0839"/>
    <dbReference type="EnsemblBacteria" id="ABX03487">
        <property type="protein sequence ID" value="ABX03487"/>
        <property type="gene ID" value="Haur_0839"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0839"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_0"/>
    <dbReference type="OMA" id="WRSVAFS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-853-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="263" mass="28300" checksum="0C04F3D0AA14F6AB" modified="2008-01-15" version="1">MSGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVFSAGIDLGDLMDLPNRYGEHWLRQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEIALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGVGRAKELIMTGRTFSATDAERWGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLIRTADFSEGVQAAIARRAAEFKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYE0</accession>
    <name>A9AYE0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0874"/>
    <dbReference type="EnsemblBacteria" id="ABX03522">
        <property type="protein sequence ID" value="ABX03522"/>
        <property type="gene ID" value="Haur_0874"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0874"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082704_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-888-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33852" checksum="99EB42C3CC1FB733" modified="2008-01-15" version="1">MTYGPPAHTSFDHSSITHQQQAVRQVVETMRQNFWNPMSLNDMAEMANFSPCYFNQVFRSIVGIPPSRYLTALRIDAAKRLLIDTTLRVIDICYEVGYNSLGTFSSRFTELVGISPQGFRELADQDNWRLFQAFLQAQKRALPSVFHSHKQIAMGSVYAPQATQTPVAIKTKRPATPTLIGLYPLPMPQGKPIAYTIAPASRLYMLPPVADGRYYVFATAFEWSQDPRSFLLLDWQREDLLVGMGDRPLWVRNGRYQNHIDLNLRPMQPTDPPLLSALFYFMVLAQQQLELFVQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN5</accession>
    <name>A9AYN5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2373"/>
    <dbReference type="EnsemblBacteria" id="ABX05013">
        <property type="protein sequence ID" value="ABX05013"/>
        <property type="gene ID" value="Haur_2373"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2373"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_317312_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2401-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="651"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="918" mass="103108" checksum="DBA809035732F2F4" modified="2008-01-15" version="1">MHAPERMLERQQRYQVADDHEFAWRQYCLGLANLRLQRLAALQLALSQARQAFGLSHDPLGLLYCEGLALAGAWLAGTNVENLQRLEGLAHRFRALGYPLEATRTDLLRVLHYYSLGQVERGLSLIQPLEASIDQLGSRYDQAYWLWISGMTYSHNHDFNQAGRLLDQAFVLFSSLHMQPECARCLFDRSWLWQRQERYAAAFNDLAAAQTLADDLNLVYLIAACAKNTGLALSRLGRYAAALDWTLDARRRYGQLARHDFINGCELNLANILYYAGLYELALKMFERLEGNYRRLNLLRMAAGSVRNQALVLRAQHQAQAAYDLLRSIEAPILQGTNQLEQAEYWQALAFALAEQGDIEQATTIFGHAESLFKQLDNQPAAAKCRLELAWLALKQHQSTDDSDNAQIHTIKHQLQQTLGYLDDRPFYRWRILYGLGLCEAAFGKTAAALDYYTQVSLIITNLRLEFFDEHASSAIFVQAHDLFTAALDLTLQANNPLALLQLSEQQRALVLRQHLDSGRSNRRIPRALQAQLWRGLRTDSLGFLDDLPPVGKLEIPEIQFDITEAFDQLDIAQLRQHLTAVYQARWVVLAYICHGSRLIRLTLTPTMLQADVIVLDAGLKRLIERASLARYRWFTYSGQQASDQPIWPELESLASHLLPPIVSQPLDYLLIVPAEPLHGIAWGTLRLNQKWLAQHTAINILPNLSHIQPTAMVVKPYSQGVMIGCSEFRDDLPALPNVEPEIAQLEAIYADQPTLTLQNAAVTKARIFELSNAGSLLGCRFLHIASHAQLRSGAGQAAYIQLWDERLSFDQIIDLQLQGTWVILSVCDGSASDVLAGEEVLSLSRAFLAAGATAVIANLWKQADDASPRLMARLHSLLHAGSDPVRALCLLQNDWLMHYDNASPLVWGGLQVISSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR4</accession>
    <name>A9AYR4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA-(Apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="11">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_2402</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="11"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2402"/>
    <dbReference type="EnsemblBacteria" id="ABX05042">
        <property type="protein sequence ID" value="ABX05042"/>
        <property type="gene ID" value="Haur_2402"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2402"/>
    <dbReference type="eggNOG" id="COG0177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2430-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="10">
        <location>
            <begin position="38"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX05042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="222" mass="24727" checksum="E0AC80BBF3412DCF" modified="2008-01-15" version="1">MLNPEKVLETLHILRERFGPRVLHTQRDPLDELVLTILSQNTSDRNSGRAFRELKGRYPTWAAVLNAESSELEETIRVGGLAKIKAARIQNTLAVILEQRGEFSLDFLRELGLHEARAWLTALPGIGPKTAGCVLCFACNQPAMIVDTHIHRVAKRVGMIGPKVSADAAHDLLESAVPVDQMYQFHVSVLLHGRQICHAQRPACERCPLTEICDFYQANSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYV5</accession>
    <name>A9AYV5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">LPXTG-motif cell wall anchor domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_4363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 3'-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19621"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:66949"/>
            <dbReference type="ChEBI" id="CHEBI:66954"/>
            <dbReference type="EC" id="3.1.4.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 3'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10144"/>
            <dbReference type="ChEBI" id="CHEBI:13197"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.1.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4363"/>
    <dbReference type="EnsemblBacteria" id="ABX06995">
        <property type="protein sequence ID" value="ABX06995"/>
        <property type="gene ID" value="Haur_4363"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4363"/>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_4_4_0"/>
    <dbReference type="OMA" id="EKAQYPM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4416-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008663">
        <property type="term" value="F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008254">
        <property type="term" value="F:3'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07410">
        <property type="entry name" value="MPP_CpdB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041827">
        <property type="entry name" value="CpdB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735113" evidence="7">
        <location>
            <begin position="29"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="9">
        <location>
            <begin position="36"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="10">
        <location>
            <begin position="353"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="633" mass="69076" checksum="73E7F9D00D3766B2" modified="2008-01-15" version="1">MRLLRAFALLLLLAVLAPLGLQSGVVSAQNEQRTVTILETSDIHGNLMAWDYYANKPAEWGMTKVASLIKQERAIDPNLLLVDNGDTIQGTPLTYYYNVIDQNAAHPMAAVFNALKYDVSSLGNHEFNYGMDVLNRYISQAQYPVMSANVRKSDGSEAFKPYIIKDVNGVKVGFLALTTPTVPTWEKPANIAGLQFADPVEVAKQYVPQIRAEGAHIVVLLQHTGWEKQPAEATKPEAWLTDPSTWRDTGSLPGENVSIKLAQEVPGVDVILTGHSHLSVPKAIINNVLLIEPSYWGRALGKVTITVEKNGDSWNVVNKDSTNISVTNVAEDQEIKALVQPYHDQTLSYISQPVGTASAEFAGGPKARYRDSALADLINNVQKQAAADAGYPVDLSLAAIFTDGGMIPAGQITLRDAYSIYIYDNTLYVMEINGDILRRALERNAEYFRQLDPNALPSDPKAVVNDNARDYNWDLYTDIDYSYDLTKPAGQRVTKLQLNGVDITPEQTLRIAINNYRAGGGGGFAMFREGKIVYQSTSEIRDLIAESVKNAGTIDPTVVNKVNFTLVPDLYAHYFGAASQPTATPVPAQPTATPAPGVPITLPDTSGNQPSYAWVWAAVAMALLALGLVVRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ39</accession>
    <name>A9AZ39_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0937"/>
    <dbReference type="EnsemblBacteria" id="ABX03585">
        <property type="protein sequence ID" value="ABX03585"/>
        <property type="gene ID" value="Haur_0937"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0937"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_0"/>
    <dbReference type="OMA" id="HERAICE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-951-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="244"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="300"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="534" mass="59115" checksum="C32EC082FCEA7BF6" modified="2008-01-15" version="1">MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLEIRAAYGLTPSLWSAFDEILHVLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQQLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQLYAEAIAERGRLDAIIESSADGMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPDNDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISVMSHELKTPVAIIKGYASTLSRTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQAGGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPKLPHVYADQERIRMVLSNLISNAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGAGLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZC5</accession>
    <name>A9AZC5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03671">
        <property type="protein sequence ID" value="ABX03671"/>
        <property type="gene ID" value="Haur_1023"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1023"/>
    <dbReference type="eggNOG" id="ENOG502ZBE0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028658_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1040-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="477" mass="52969" checksum="17F12AFBFAECB273" modified="2008-01-15" version="1">MKITTSQELIGWHRYLEQLGPRLTGSEAHQAFIEFLATELTSLGCEVQRDRYYFTRWQAQNWSLALLDSAGNETSIPCSFYYPYSGSTPPEGIIGELVDCGKSPGNFQQAAGKIALVEVAVPALPTMLFLHPTKFAQAQKLPKLLRNPTLGSFLTGPNLAAAKQAGVKGVICIWSKISAANADAQYLPFTTSYQACPALWVNAAVGQQLKQAVGQKIRFTLEATLTEQCPTDSLYVVLPGQQSNESLLINTHTDGPNAPEENGALGLLALVRWFKQQQHQRNLIFIFATGHFQLPQLGKHGQATSTWLAEHPELWNGQQMRAIAGVTLEHLGCTEWLDNRALSDYQPSQQPELELTYTTSPMLEQLYYTALLQRTKQRVLTIMPINEIYFGEGEPFYKANIPTISLIPAPNYLCATPSNAVIDKLDFDLMQQQIETFARVIKMIDQISTSHLGVAEPQPFSLVGSVFRRMVGANQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZI0</accession>
    <name>A9AZI0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05124">
        <property type="protein sequence ID" value="ABX05124"/>
        <property type="gene ID" value="Haur_2486"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2486"/>
    <dbReference type="eggNOG" id="COG1002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2012100_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2514-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="123" mass="14013" checksum="576AAE4AE8DA18A5" modified="2008-01-15" version="1">MNPPLLIVSDLDSLVIHTNCTNTVKKVTTHTLDETLTKNGLGMIRSIFYAPNTFRSPITPERVTEEVAAKFARLAQLITRYEKHAAPQEIAHFLTRLLFCLFAEDIRLCFCRSFNPLPRILVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ3</accession>
    <name>A9AZJ3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2499"/>
    <dbReference type="EnsemblBacteria" id="ABX05137">
        <property type="protein sequence ID" value="ABX05137"/>
        <property type="gene ID" value="Haur_2499"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2499"/>
    <dbReference type="eggNOG" id="COG3938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036729_1_0_0"/>
    <dbReference type="OMA" id="SHVLWTG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2527-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="309" mass="32980" checksum="92E44C266AA4F0CF" modified="2008-01-15" version="1">MRLAIVDSHTAGEPTRIVIAGGPDLGGGTVAQQRDVLTQHHDWLRSAVVNEPRGSDVLVGALLCPPSDQRCCTGVIFFNNVGYLGMCGHGTIGLVATLAHLGNIEVGEHLIETPVGIVSATLHADGQATIENVPSYRYRANVPVDLPNHGRIHGDIAWGGNWFFLVNDHGQDLQLANVEQLTAFSWQIRQALEAAGITGADNGLIDHIELFGAAAEGANSRSFVLCPGKAYDRSPCGTGTSAKLACLAADGKLAPNTPWVQESIIGSRFQAEYHHHEQAIIPKITGSAFVTLEGQLILHEADPFRWGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZJ5</accession>
    <name>A9AZJ5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sarcosine oxidase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2501"/>
    <dbReference type="EnsemblBacteria" id="ABX05139">
        <property type="protein sequence ID" value="ABX05139"/>
        <property type="gene ID" value="Haur_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2501"/>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153062_2_1_0"/>
    <dbReference type="OMA" id="PRAPFCG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2529-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="80" mass="8729" checksum="41A0870511130C1E" modified="2008-01-15" version="1">MKQIRISINGTEYQVTEHSNLAAVLMDKAIANRRSVTGEPRMAVCGMGSCGECRVTINQQAHQLACLLQCCDGMEVDCEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZM7</accession>
    <name>A9AZM7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_4449</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4449"/>
    <dbReference type="EnsemblBacteria" id="ABX07081">
        <property type="protein sequence ID" value="ABX07081"/>
        <property type="gene ID" value="Haur_4449"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4449"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_0"/>
    <dbReference type="OMA" id="CFGTSGP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4504-MON"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="194"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="386"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX07081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="570" mass="62558" checksum="DB7B3531ADF0F393" modified="2008-01-15" version="1">MKTLTGAQMMCEALIAEGVDVMFGYPGGAIMPFYHALPEYPQLRHILVRHEQAAGHAAEGYARTSGKVGVCVATSGPGATNLVTAIADAMMDSIPIVAITGQVVTSLIGKDGFQETDVTGITQPITKHNYLVTDVRDLPRVFKEAFHIARTGRPGPVLIDVAKDTQNARGVFEYPESVDLPGYKPNYDGNRRQIKEAANLLNQAKKPLIMAGHGILLGHASVELREFAEKTGIPVITTLLGISCIPEDHPLSLGMPGMHGWVHVNRAIQECDVLFTIGARFDDRVTGKLDTFARNAKIIHVDIDPAEVGKNVITAVPIVGDAKRVLENLTEIVNANEHSEWLNHIRDIQATRSKRQRDPESGMFTPHHVYAEFTRIMQGEFRVCTDVGQHQMWAAQLIEYMKPHTHITSGGLGTMGFALPAAMGVQVACPNEEVWAIAGDGGFQMNLQELATVVQESLPLKICIINNGYLGMVRQWQELFHERRYSATPMWSPDFIKLADAYGIPGVRVERAEDVAEAIQQARSTNGPFLIEFVVEREVNVYPMVAPGASISDMFEDPNEVEIEDVVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B038</accession>
    <name>A9B038_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1097"/>
    <dbReference type="EnsemblBacteria" id="ABX03745">
        <property type="protein sequence ID" value="ABX03745"/>
        <property type="gene ID" value="Haur_1097"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1097"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_0"/>
    <dbReference type="OMA" id="HVTPHEI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1117-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14512" checksum="EAB91FFC8B89C9E8" modified="2008-01-15" version="1">MHILIVDDDQDNRTILTTRLQRRGFQISTAKTGIEGLMLALQLKPDLILMDMSMPELHGWGATAQLKASPQTRAIPVIAITAYTLSGDRERCMAVGCDAYVEKPIDFNHLLSTIQRVAERHSIALEIKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B075</accession>
    <name>A9B075_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05184">
        <property type="protein sequence ID" value="ABX05184"/>
        <property type="gene ID" value="Haur_2546"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2546"/>
    <dbReference type="eggNOG" id="ENOG502ZMUU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2142438_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2574-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="13029" checksum="C3F326FFB03FD566" modified="2008-01-15" version="1">MAEFTLWSPEEMQERAKPKRAVQRETRERIIAEYTNYFQNAKAGFGGQVVLGDDEDKRKLRALVREAASRSNLVLRFRPIKDKNRIEFLVIDPQSQPARKTGARRGRPKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F7</accession>
    <name>A9B0F7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_4544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4544"/>
    <dbReference type="EnsemblBacteria" id="ABX07175">
        <property type="protein sequence ID" value="ABX07175"/>
        <property type="gene ID" value="Haur_4544"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4544"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_8_1_0"/>
    <dbReference type="OMA" id="ATTLMTQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4599-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX07175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="41787" checksum="476D751B049455D6" modified="2008-01-15" version="1">MPKELTVRVSARTVGWTLLIFSGVWITILLNHVLVLFFVAVLLAVAISGVVQRFEQLRIARPITILVIYTIIIAMFISLGFVLVPMVSQQVRLLAEQFPNLVRQPTQQASAWLAQQFPTLRVPLPTGDLAGQAAHYAGTVVGGFSGAAFTFGRTLMGVIINFIVVLVLAFFLVSRANVASNFIKLMIPNRFQERLINVTNVIGRRLGRWVWAQLTVATFYAVCFGMGLWMLGVPYPVALGVIGGMLELIPYVGGFVATILTMLVAFTVQPMLAVWVLVLHLIVGNIEVHIIAPKVMGHAVETHPVITILALFSGIELLGIIGGVIAIPLAVVGQALVEEFWIKRIREAQPAAESLAVQAKAPIVRRTQLRRRPTLRKRQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0I9</accession>
    <name>A9B0I9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4576"/>
    <dbReference type="REBASE" id="16540">
        <property type="entry name" value="HauMrrP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07207">
        <property type="protein sequence ID" value="ABX07207"/>
        <property type="gene ID" value="Haur_4576"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4576"/>
    <dbReference type="eggNOG" id="COG1787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101688_2_1_0"/>
    <dbReference type="OMA" id="MRYYAAD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4631-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="50"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="169" mass="19304" checksum="07D56EC7AE29EE8D" modified="2008-01-15" version="1">MNIFPESWNTIGRWLIIISAGIIILTIIISFLEVFIRRRRLIRSGIVDVDRMSGTEFEHFLGVVFRQYGYQIEHTGKSGDYGADLIIKKAQSRTVIQAKRYTKNVGVKAIQEAVAAKKVYHCQGAIVITNSHYTKQAQVLAKANDVVLWDRERLLKVMLMLKNQPINQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0L8</accession>
    <name>A9B0L8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4605"/>
    <dbReference type="EnsemblBacteria" id="ABX07236">
        <property type="protein sequence ID" value="ABX07236"/>
        <property type="gene ID" value="Haur_4605"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4605"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_0"/>
    <dbReference type="OMA" id="DIYVLIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4660-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="14"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="391"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="618" mass="65592" checksum="2A38B4A29F98075D" modified="2008-01-15" version="1">MRIEDLIGKQLGRYKINHILGRGGMAAVFEAEDTMLRRLVALKVLYAQYVADANLVERFRREAILAARLEHAHIVPIYDVGEADGVVYIAMKLLTGQSLQDSLLIDSTLSPERVGEIVRQVASALDYAHGRGVVHRDIKPGNVMLDADNQVVLTDFGIAKSLDAPGLTTTGVMVGTPDYMAPEQIDSKIGPVDARADIYALAVMAYRMLTGARPFDGSTTDILLAHLSRVPEAASLRNPHVPPSIDAVLSAALAKNPADRTKSAGLFARALNEAIGSPTGIAATPPPGAKQAVVIPSVAAEQIVAKAQGATQTSAITRRKRPSTWPILLLIGLIITGVLMFVTDTVLDNRQEAKQTLATEAAERGQYQTQVAQIGITQTALAAQINPTPTATMPVSSTATVEASAPSPTAEAAQPSQAAQTTARPVATQVVPIASSPTSAPTNNPPTPIVATPTVLAACVGPLQGGFGTLWRTNLNIAEALGCPSSGEAASTASIQYFDGGMMYWVGNSDQIYVYYGAAASGSWQSFANPNDPSYDEPRETAPAGKLEPIRGFGTLWHTISAIRSALSWANSPEYPITGVVQYFPNGMMLFSPALEGRPDRIWVMTNDGSWSRYTDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0T0</accession>
    <name>A9B0T0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1152"/>
    <dbReference type="EnsemblBacteria" id="ABX03800">
        <property type="protein sequence ID" value="ABX03800"/>
        <property type="gene ID" value="Haur_1152"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1152"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_0"/>
    <dbReference type="OMA" id="FQRNIMS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1174-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="85"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="296" mass="33658" checksum="291F24DA4262DDD4" modified="2008-01-15" version="1">MQRPAIEPTKRWQKSSRTFGIYLLMTGIALFTLFPILFMLVTAIKADESQILREMSTFAAFLPTGELSLQNFRDVFERVPFAQYLINSVIIALSIVICGLFVNSLIAYALARMQFRGQKLLLAIVVALIIIPFQAVAVPLLLIVNQLPWFDGRMTWLDSYHVQIIPFIADAFSIFLFYQFFLNIPKDIEEAALVDGASRFRMYSQIIVPLSRPVFATVAILQFLTHWGDFLWPLMVVRDPAVRPLTVGMQAFFGQMPRQWGDIMAFATMVTLPVLIIFLLFQKWFVQSVASSGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0Y5</accession>
    <name>A9B0Y5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1207"/>
    <dbReference type="EnsemblBacteria" id="ABX03855">
        <property type="protein sequence ID" value="ABX03855"/>
        <property type="gene ID" value="Haur_1207"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1207"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_0_0"/>
    <dbReference type="OMA" id="IAQHCIL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1229-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="37503" checksum="88CB84B154C703ED" modified="2008-01-15" version="1">MSKRVLVTGANGHLGSVLAQMLVERGVDVRASVRNRSQIKPQLAYEQVYADLMDMDSLQQALVGVDTLYQVAAVFKHWSRNPQREIIQPNVEGTRNILRAAAQAGVKRVVYVSSIAAVDKNNPQRQIPADETTWNQYTYGNPYYQSKIASEQLAWKLAKEYGLEMMAGLPGTIIGDPNGRTTPSLGILELVLSNKMPLDINMDFNFVDVADVAEGLIAAERQGRAGERYILANDQSLPLRRIFEIAQEFNPKIKVPMRVSKGITNVVAGMMELVANVTGREPMILRSQVGLYCGIEQRLSIAKAKRELGYNPLPAVDAVRKTFQILARQAPKQVALGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B181</accession>
    <name>A9B181_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4637"/>
    <dbReference type="EnsemblBacteria" id="ABX07268">
        <property type="protein sequence ID" value="ABX07268"/>
        <property type="gene ID" value="Haur_4637"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4637"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_2_0"/>
    <dbReference type="OMA" id="FLAEGPQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4694-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="34"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="262" mass="28144" checksum="665786D6244CF075" modified="2008-01-15" version="1">MLIDLITSTANHHVKYLRSLLRSRKDRHSERRFVVEGVRLVGEALNFATPSLLLYVPEQLASTERGQQLLDLIAQLPNAFATTPAILAGLSDVETPQGIIAVIPMPQFTSQSASLILMLDGVQDPGNVGTLLRSAEAAGVGQVLCLPGTADVWSPKVVRSGMGVHFRLPIVDGLNWETALPLIEHCQQRFAAVQDSPLSYDQADLTQPTVLIIGNEANGVSATTLSYSSTITIPMLGSLESLNAAVAGSVLLFEAARQRRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B183</accession>
    <name>A9B183_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="9" type="ordered locus">Haur_4639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4639"/>
    <dbReference type="EnsemblBacteria" id="ABX07270">
        <property type="protein sequence ID" value="ABX07270"/>
        <property type="gene ID" value="Haur_4639"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4639"/>
    <dbReference type="eggNOG" id="COG0290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054919_3_2_0"/>
    <dbReference type="OMA" id="RNMIMFL"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="8">
        <location>
            <begin position="19"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="7">
        <location>
            <begin position="95"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX07270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="219" mass="25365" checksum="30459451E3FE9516" modified="2008-01-15" version="1">MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEVAPNASPPVCRLMDYGKYRYEQTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARRFLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHGVLEQKPTLEGRAYSLIMAPSPSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1A1</accession>
    <name>A9B1A1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_4657</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4657"/>
    <dbReference type="EnsemblBacteria" id="ABX07288">
        <property type="protein sequence ID" value="ABX07288"/>
        <property type="gene ID" value="Haur_4657"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4657"/>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_0"/>
    <dbReference type="OMA" id="LAFNQMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4714-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029150">
        <property type="entry name" value="dCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14827">
        <property type="entry name" value="dCache_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="343"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="539"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="657"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="893" mass="98106" checksum="44BC542874FEBDC0" modified="2008-01-15" version="1">MFVNLRRRLKSRIRYKITLPYLLLLAFLSGLLIVIIFWLYAQSLQNQLNQSLRTSATNTGVGLETIEAQILDNLRLIVTSPANEKEALLSTAEAFSKNDVDQVEQIINNAFNYFKPSRLIALNADGQVLVDAASSTVLSRSPSLVGSTELAKDSLIQAVLRGQVDDYGDKYASLLRIGANPPYTMFFVVAPVKLTVGSSEQVVGAIIYAEPLERIVNEELPPRNGATITAILNSDGSVLTSNPPQEADELLIDANQIEQIKASQTNPDPETRGTLFTTIQRGDTSYQVMYSPMRIRRALNGYFAVGLPRSNIDRAWQQARVLIFLFGVLSLISIIWISVRVTRSITVPLSELVSTALRIKSGDLEGRSFVSEENELGTLATVLNDMTDRLLDLYRTSRQLGTELTLDGVLTQTTAAVQRLIPDSEVDALVVEQGVWHYVTTESVREIERPFPATSLETLAPMVTITENPALDSALRPLAPNLQLVLPLRTQQQVIGSLLVKNDRALPPASSIREPLSAIASMTATAMQNAVLYTTVQDEASRKQAILQSIADGVIVLDPDGKVILVNHTATAMLGASEADLLGKSFAEFQLTPLSGGAELFATPTATTFYETTSQRILTMNAAPVEREGLQSGEVLVLHDVTEERAMDRAKTDFIATISHELRTPLTSICGYADLLLRGFVGPLTDEQTQFMSTIRQQGQSMVEVLQNVIVIASIEAGNMEPQIEQHSLDELLPPIAQALQKGFDQKQLKLIIDLPENMPYIVVDRDHFKIMLTQLLENARRYTQTGTVTVQAKAVEQRIQIAVIDTGPGIASQDFERLFERFQRGGEQSGLTSKERGIGLGLAITKQLVEQNNGKIWVESEQGVGSSFIMQFPLMQLEPSEYNLVNATATNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1C5</accession>
    <name>A9B1C5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4681"/>
    <dbReference type="EnsemblBacteria" id="ABX07312">
        <property type="protein sequence ID" value="ABX07312"/>
        <property type="gene ID" value="Haur_4681"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4681"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_3_0"/>
    <dbReference type="OMA" id="EERWHKD"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4738-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="54"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="358" mass="38568" checksum="ECB11970C5CD3CA6" modified="2008-01-15" version="1">MRRRFVLLVLLLVLVGCGGAEAPKAKIIALLLPEQTTKRYETVDRPWFEREMNLLCNDCQVLYYNAQNNPSLQQQQAEEAIKAGARVLVLDPVDSVDARTIADHAAEQSIPVVAYDRLILNSPGVTAYISFDNQKIGELQAESLIAGLAARGLSNPKILLLHGSLSDNNASEYKRGAKKVFDPLVAAGKLTIIGEFDTPDWKPAEAQQYVERMLAAGDQIDGIYAANDGTAGGALVAVQAAKLEPLPLITGQDAELTAVQRIITGEQHMTVYKAIRPQAEAAAKIAHALMVGQPIPTNLVNNRTVANGIMNVPAILLNPVVVTKATVKDTIVSDNFWSPQQLCPVKLVPACEAVGIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1K0</accession>
    <name>A9B1K0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1237"/>
    <dbReference type="EnsemblBacteria" id="ABX03885">
        <property type="protein sequence ID" value="ABX03885"/>
        <property type="gene ID" value="Haur_1237"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1237"/>
    <dbReference type="eggNOG" id="COG0398">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038944_8_2_0"/>
    <dbReference type="OMA" id="GILRINW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1259-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="26393" checksum="D2DBEF730A4D83C1" modified="2008-01-15" version="1">MTTSTSTSTKSFWQRHWQKLLAAGFWVLLVGGYLWYSWRNQLSPAAAVGQLIELLKSDVGVLIYIGVYLLRPLIFFPATFLTLAGGSVFGSVWGLIYTVIGANGSALVAYTIGRFFGQPEQNQNQTGLVNGYIERLRRNSFETIMLMRLIFLPYDLVNYLAGILRINWKQFLLATMLGSFPGTLTFVLFGASFEGDFAKAEFSFNPWAFAGSIVIFIISIAISRWLKRREAAKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1S9</accession>
    <name>A9B1S9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VanW family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2733"/>
    <dbReference type="EnsemblBacteria" id="ABX05371">
        <property type="protein sequence ID" value="ABX05371"/>
        <property type="gene ID" value="Haur_2733"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2733"/>
    <dbReference type="eggNOG" id="COG2720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_587728_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2764-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007391">
        <property type="entry name" value="Vancomycin_resist_VanW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04294">
        <property type="entry name" value="VanW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735399" evidence="1">
        <location>
            <begin position="29"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="480" mass="54397" checksum="4EFC6594CD232EBB" modified="2008-01-15" version="1">MPGQRWRLLPSLVLGLALLGLAPSVPTASVSAAVQAQQTTAWEPYRYFAATGHNISFDVKRFYERQGDLEVFGLPLTEVIWENGFQVQYFERARLEIHPENKGTDFYILATRLGAVAAEGRQNEDPFVWRTGPSYEGATFYPESGHSLGNGFRDYWTKYGGLYTFGYPISEEFSEVNAEDGQTYTVQYFERARMEWHPEHAGTKWEIQLGLLGKQYINRMGIDQNLLKPALEVQKLGSATTYYRGSNAERINNIKRAADRFKGVTVKAGQVYSFNQNVGDVSEEAGFTDGYAIVDGKLEKVVGGGLCQVSTTMYRAVFNSGMPIIERYGHSYIVYYYENILGFDATVFVPDVDFRWKNDLGTDIFMWTDTDTSAGRVTFSLWGYGDGRRATMEGPTYSNEQKPGKPVWQYDKTMRRGAVEQLVHGRAGMDVTMYRVINKANGTSNRERFFTRYYPWEDFYLYGPGVKPPAGVTIAPPRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X8</accession>
    <name>A9B1X8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2782"/>
    <dbReference type="EnsemblBacteria" id="ABX05420">
        <property type="protein sequence ID" value="ABX05420"/>
        <property type="gene ID" value="Haur_2782"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2782"/>
    <dbReference type="eggNOG" id="ENOG5032S2F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2301665_0_0_0"/>
    <dbReference type="OMA" id="QLIYIKE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2813-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010753">
        <property type="entry name" value="DUF1330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07045">
        <property type="entry name" value="DUF1330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1330" evidence="1">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="100" mass="11489" checksum="D91980A9B6C8348B" modified="2008-01-15" version="1">MIYLTQLIYVNSGQAGVVEQFEALVLPLLPQYNGRLLLRIRPNDATIIEQTIETPYEIHLLEFASQADFERYLADPERQACLHLKEQAIRSTFVIQGQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z5</accession>
    <name>A9B1Z5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2799"/>
    <dbReference type="EnsemblBacteria" id="ABX05437">
        <property type="protein sequence ID" value="ABX05437"/>
        <property type="gene ID" value="Haur_2799"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2799"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_0"/>
    <dbReference type="OMA" id="IDRVWGS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2830-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="132"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="132"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX05437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="236" mass="26487" checksum="F0C4AA0C5042ABBA" modified="2008-01-15" version="1">MSQPQAAARILVVEDEKEIAGYLRRGLAFEGFTVEVAHDGPTGIAAARERPADLVILDIMLPGMDGFEVCRRLRAGSDVPIIMLTAKETVPDRVMGLESGADDYLIKPFAFEELLARIRALLRRHVARTEGPVVLQVNGLEMNTASREVTIAGRAVQLTAKEYELLELFMRHPGQVLTRDVIYDRVWGYDFGGESNIIEVYVRYLRQKLEESGEGRMLHTVRGAGYILREQPYGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1Z8</accession>
    <name>A9B1Z8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2802</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2802"/>
    <dbReference type="EnsemblBacteria" id="ABX05440">
        <property type="protein sequence ID" value="ABX05440"/>
        <property type="gene ID" value="Haur_2802"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2802"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045539_5_1_0"/>
    <dbReference type="OMA" id="RHVLVWY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2833-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="368" mass="40040" checksum="F7EF37AAF53FB430" modified="2008-01-15" version="1">MKEWVTKTAWPLTQRTFKAWTVDDCSRMAASLAYYAVFSIFPLILLLLSILGFWLRLQGDTNTNAEETLVNSLMQVFQTSPQVGVDDSAIRTALTEILKSLSQQAGTNAPIALATTFFAASGIFVQIDKAFDVIWDIQPQQGNFLHTVKSTLIERGKAFALVLVIGLLLISSLILSSVLQALENLSKSFDLPGVGVGWQIFTFATAFAINVLVFFLLFFAMPKPKMRWRDVLPGAILTAALWEIGKIVLSLFLGGNKYTASTTVAAFIALLAWIYYASQIIFFGAEFCRVYTDWNSTKRAKQAPAVALPTPPDLPTTALPPALATAQQKASYAVGGTALGVVLGVLMSIVGTLVAIIQFIQTLRKGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A9B253</accession>
    <name>A9B253_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4772"/>
    <dbReference type="EnsemblBacteria" id="ABX07403">
        <property type="protein sequence ID" value="ABX07403"/>
        <property type="gene ID" value="Haur_4772"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4772"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024955_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4830-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019139">
        <property type="term" value="F:cytokinin dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009690">
        <property type="term" value="P:cytokinin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015345">
        <property type="entry name" value="Cytokinin_DH_FAD/cytokin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09265">
        <property type="entry name" value="Cytokin-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="68"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="483" mass="53686" checksum="232A6DAF761ECDEB" modified="2008-01-15" version="1">MTQLSRRTFLKSLVAGAVVVGFDRATSSWVTSAHAAEQLAPNFPTFDGVLYTDAATRAEAADDYGHIIHRTPNAVLKPGSVNDIVRLVRFAKNNNIKISGRGQGHSTYGQPQIQGGVVIDMSTMNAIHEIGRDYVIADAGLKWHQLLDSTLAEGLTPPVMTDYIELSIGGTLSVGGIGGASHQHGVQIDNVIELTVVTGEGNLETCSKNRNKDLFESVLGGLGQFAIIVRAKLKLIRAETHARVFNLFYDDIETFTGDQTRLIRDGRFDYVEGQVVPKAGGGWNFMLEAVKYFSANNTPNNTRLLRNLSYNQGTEVISDTTYFAFLNRLEATEAFLRSIGVWFLPHPWFDVFVKSRHVNQYVGNILETLTLDDTGQGPILLYPVKTNKFTKPFFRVPDGEIVFLFDILRTAPNIPEVINAMMASNRELFETNRDLGGNRYAIGAIEFDQNDWRQHFGNVWNDFRRAKNRYDPCNILGGGQGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2A4</accession>
    <name>A9B2A4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1301"/>
    <dbReference type="EnsemblBacteria" id="ABX03949">
        <property type="protein sequence ID" value="ABX03949"/>
        <property type="gene ID" value="Haur_1301"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1301"/>
    <dbReference type="HOGENOM" id="CLU_1270865_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1323-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735199" evidence="1">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="217" mass="23856" checksum="97646EDCF7956FCD" modified="2008-01-15" version="1">MRFCCLLGWIIVLLMGCQAKQDPLADPEQETSMLAIDQATVVTLREGTDLHIEGLNLGVLQILYAADQPQQSIGVRIRFLTKPAIFNYHTQLMLDQTITVANYQVQLLSIEQSSIQVAIRLTAEQAPILPIEALGQEQLLIAPANSSVGDGYLTITIGDYDPANGQVELSFWVSSSVPELKQTATLGQVIEYQGYRVRVLWLPNAAYPMVALGLQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2B5</accession>
    <name>A9B2B5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ABX03960">
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    </dbReference>
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    <dbReference type="eggNOG" id="COG0823">
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    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
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    <feature type="chain" id="PRO_5002731811" description="LTD domain-containing protein" evidence="1">
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            <end position="345"/>
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    </feature>
    <feature type="domain" description="LTD" evidence="2">
        <location>
            <begin position="243"/>
            <end position="345"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="345" mass="38043" checksum="6D7FD3EADA2EA754" modified="2008-01-15" version="1">MRRWIWLLLVVGFLPRPVAAHNLCFVEVSNPYCLEEPFSDYWEDNGGLPVFGYPIAAAKAEANPDTDMSYHTQWLERNRFEVHPENAGTAYEVLLGLLGKERLQQLGRGVAPREVGPQTGCLWFEETGHNVCDQANGLGFKSYWQSHGLKIPGLDTYARSLQLFGLPLTGVNLETNANGDTVQTQWFERARLEWHPNNPDQFKVLLGLLGKEVYTNRGNPILPVPTPTPAPIVTPTPAPPPPSFNDCQADPTVASNFPVRIVSVDKRAETVMIQNVSNAPVAIDGWKICSIRGNQLHATLGGSLAAGETRTINSTAGAPIWSNTEKDDATLYDGQGRLISFLEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2I8</accession>
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
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                <person name="Ivanova N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
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    </reference>
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    <dbReference type="BioCyc" id="HAUR316274:GHYA-1409-MON"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="EMBL" id="ABX04033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="373" mass="42077" checksum="F07E148A186CBC90" modified="2008-01-15" version="1">MKSVRELHMQAMDFADLALHAKHTGDIHSFIAYSRQALDLEIEAAALVAPFDTEPTRSILHRSAATLALDCDEHRLAERLIATALAGNPPYEIAEELRDLLEQVHFQRHLAIRDVKIDPGQVQVSMTGQEIYPGLTLMDIFLSRLQDIERMIFRTVERLLKREFRERGGTAQVLQEGYSVYMSAPRAGSFAVTLQLGRQQRFDIPEIDLSSIVLEDVIQNISLVNKGDFQSLKERIPNESYYNNFVALAKKIAPDGQDVRMVGLTTLQSGSNEVLSVAFDKTPPEISTLAGSNIATKKDKSKHQTFVGQLKHADEISANNTIQLLFSDNKKQKIIVPPGMMNDIVRPLWGEKVEVFCEKRGNSYYLREIKRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2M2</accession>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
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                <person name="Schmutz J."/>
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                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2835"/>
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        <property type="gene ID" value="Haur_2835"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2835"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2680991_0_0_0"/>
    <dbReference type="OMA" id="IHGTRFY"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="74" mass="8179" checksum="68533A7DBAFE14FD" modified="2008-01-15" version="1">MILSGTRPAVIQAVQAVSLHGSIFYDVTFAHDDQPERLIKARLGSEVMYANPQAGDQVTISYLMNMPTQVSKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2N5</accession>
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        <submittedName>
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    <organism evidence="2 3">
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Glavina del Rio T."/>
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                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
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                <person name="Richardson P."/>
                <person name="Bruce D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="AKR"/>
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    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
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    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="311" mass="34040" checksum="A33A40C2A5D9983A" modified="2008-01-15" version="1">MQLRQLGKSELRIPKVVIGGNVFGWTVDRAQTFRLLDAFVAAGLNTIDTADVYSAWVEGNQGGESETLIGEWIKQRQRRDDLIILSKVGAGTGLAKAHIAQAIDASLQRLQTDYLDLYQAHVDDANTPLDQTLSAFAELIQQGKIRVIGASNYSAERLQAALAISQELNIPRYESLQPLYNLYDREAYEAQLETVCQEADLGVIPYSTLASGFLTGKYRSEADLSQSARGSRVRSYLNPRGWIILKALDEVAAEVQATPGQVALAWQIARPSITAPIASATNLDQVNDLIKAAQLELTSSMIDYLNQASQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V8</accession>
    <name>A9B2V8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH ubiquinone oxidoreductase, 20 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3385"/>
    <dbReference type="EnsemblBacteria" id="ABX06021">
        <property type="protein sequence ID" value="ABX06021"/>
        <property type="gene ID" value="Haur_3385"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3385"/>
    <dbReference type="eggNOG" id="COG3260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2000767_0_0_0"/>
    <dbReference type="OMA" id="WATSPHE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3422-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="124" mass="13055" checksum="2693AF97DCE0F30C" modified="2008-01-15" version="1">MIAVYHLNAGSTGIEVRILAEAIRSARNLTWAATPAHADIFVLTGPIPLLLRPALSNVWRDFIADRAPLIALGRASIDGHPFGRGGLAELPEIQVAAKIDGDPPTVAAIQAGIVQALNARTAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2V9</accession>
    <name>A9B2V9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3386"/>
    <dbReference type="EnsemblBacteria" id="ABX06022">
        <property type="protein sequence ID" value="ABX06022"/>
        <property type="gene ID" value="Haur_3386"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3386"/>
    <dbReference type="eggNOG" id="ENOG503472Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1022634_0_0_0"/>
    <dbReference type="OMA" id="HERWLAY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3423-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="281" mass="29833" checksum="35FE55E00164F4FF" modified="2008-01-15" version="1">MNTLLQQLIAALLYPGMLTTMLLTLAVIGITKLHAPGGGLSRGFLAALQGKTSLNLALAALLALIAPAFLPWAGSPLATPRLGQLWLAWALLETSFMLALMPGLQSLAASSVRAAMREAQLSSAGRIVLWLALGVALWTGDNWQWNIVPARVLALIAAAMALPVALGWGPFAHDWSLTPGGPEAELNRASAELAQWGRAIRATVLLTLIPLLGFPITAGLHWSLHVALTIATTLALAGVGRYINGSTVRQPLNESLRWCYTRALPLALLSGIVLVAMQRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X2</accession>
    <name>A9B2X2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipid transport protein domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3399"/>
    <dbReference type="EnsemblBacteria" id="ABX06035">
        <property type="protein sequence ID" value="ABX06035"/>
        <property type="gene ID" value="Haur_3399"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3399"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_331978_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3436-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015819">
        <property type="entry name" value="Lipid_transp_b-sht_shell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011030">
        <property type="entry name" value="Lipovitellin_superhlx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015816">
        <property type="entry name" value="Vitellinogen_b-sht_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001747">
        <property type="entry name" value="Vitellogenin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01347">
        <property type="entry name" value="Vitellogenin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00638">
        <property type="entry name" value="LPD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48431">
        <property type="entry name" value="SSF48431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56968">
        <property type="entry name" value="SSF56968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51211">
        <property type="entry name" value="VITELLOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002734518" evidence="2">
        <location>
            <begin position="32"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="Vitellogenin" evidence="3">
        <location>
            <begin position="55"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="865" mass="94142" checksum="93B7F90791CFA3DD" modified="2008-01-15" version="1">MAHPRLVRLFSLILLTALTVQLVLIPSSAAAQSQSKQATPASELPATLPGEHYNYPANSIYQYYWSTLVDTVSTTQEQSSGVRNDSNSFNLQGYLQVERYAYDSYSAYLRAQVINPVMYNKTEAGWQQVTDPEVIGRTADAELARPFYFQQDRNGTIYGLYFDSADTEDVQNIKRAALSQLQMYLFYDPNPIGECSDPTQIQCLQPYSIGESDVSGVYTADYTSRMIDAQTVEITKKRTEKSYKSFADRSIANAEATKIESTSVAIYDLRAGILLKNTTTQRIRSGFSTENSLNNYEGSGYGIQSGADSDDSIRYEGTIPGFLEPQSFEGKASTKSITNLIRTIEGKEYKSADIVASVTSNKANADRGLAAADLATALKELAAAPSDPNAVTRLRATLNTVDGALAQLDQQLSKGRTNPALHEGIIGALTGVVDSQAQAMIIKHFVGNQSLNQTTRTQALTALTVGEPSAETIAAVRNLVQANGSDAKQALLVLGAIANNVQAKQPQLAQELSQIIETKLAKAKTDLDRDLALRALGNAGPATNLSVISGYLSHSNEIVRTSAIDALRKFPAAETQALLLQAYTNETSPVARHTARELLYANGDAPTLNAFDWNWQKFVGGGDLKGELKARLYLSDGPDITALAHGEAKAHAWSWSYTLADAKATSYVQTENGTKYRYFEAYVKVLGNNVFTPIKERIACGVQRTGNLYQTTMTFFSVTKTFMVGPIPIQLGLSASGSISIPWKIVATACDVPISASANVSITPTVWASASATAAVTIFIARGGVGINADFLKTSLEAKASATYHITNGFHGNLGLNISVQPLAVRIFLWYQLRKWNGSWKSRNEWTIWNWSAATQTWPIWNTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2X6</accession>
    <name>A9B2X6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3403"/>
    <dbReference type="EnsemblBacteria" id="ABX06039">
        <property type="protein sequence ID" value="ABX06039"/>
        <property type="gene ID" value="Haur_3403"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3403"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1040916_0_0_0"/>
    <dbReference type="OMA" id="PSHFNSQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3440-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="265" mass="30148" checksum="A176AF30F5794484" modified="2008-01-15" version="1">MDLLDAIRSRRTTNGPFEDRPLDPTHVQTILEMAACAPSHFNSQPWRFVVIQDQTTRMQLAEIAGESMQKLMAGGRFWQRYRKYFRFSKQEVDQRGDGILIDNMPAILKPFAKYIFTERGGELMAKFQVPKVLGKDARKLVAGSPLILGITLDKSEYKPDDLSGMYSLLSLGAVMQTIWLTATSLGIGMQFISTPMEVEGQWEKITKLLQIPDEHSLMVLYRLGYIPQAADRPTIDWTSSQRKRTAALAYANRWDQPFEPATKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3H9</accession>
    <name>A9B3H9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2913"/>
    <dbReference type="EnsemblBacteria" id="ABX05551">
        <property type="protein sequence ID" value="ABX05551"/>
        <property type="gene ID" value="Haur_2913"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2913"/>
    <dbReference type="HOGENOM" id="CLU_2142439_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2944-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="112" mass="12594" checksum="92E9450124922A7D" modified="2008-01-15" version="1">MPAIIAILGLFMLRTQVLAMPNLARVAIMLVGCGFLLWIAWQIWQNRQGSRLFSSSPQVQYWRGQRIEMKPTQSYKKSLKLEPRTIALIALYGLAGLTGIIGTLLNLGRFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3L1</accession>
    <name>A9B3L1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2945"/>
    <dbReference type="EnsemblBacteria" id="ABX05583">
        <property type="protein sequence ID" value="ABX05583"/>
        <property type="gene ID" value="Haur_2945"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2945"/>
    <dbReference type="eggNOG" id="COG2236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096723_0_0_0"/>
    <dbReference type="OMA" id="FPWDYEP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2977-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="184" mass="21162" checksum="071BE9DD264F7758" modified="2008-01-15" version="1">MASYDYRTRRGVDPISWQRFEELTRQLAVQIAPWGPELVLGIARGGLFPATLLSYALRRELYPIRLTRRFEDQVVRRDPSWLVKPPEKVRNRRVLIVDEMADSGQTLLVAALVVRDMGAADVKTVALYAHTWANPRPDYVGLLSDQLIMNPWDREILQDGHFVQHPEYTAAIRAQDDEQPSEQP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B412</accession>
    <name>RL3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplC</name>
        <name type="ordered locus">Haur_4915</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B412"/>
    <dbReference type="SMR" id="A9B412"/>
    <dbReference type="STRING" id="316274.Haur_4915"/>
    <dbReference type="EnsemblBacteria" id="ABX07545">
        <property type="protein sequence ID" value="ABX07545"/>
        <property type="gene ID" value="Haur_4915"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4915"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044142_4_1_0"/>
    <dbReference type="OMA" id="KRMAGRY"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000141876" description="50S ribosomal protein L3">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="212" mass="22881" checksum="A80FE8806F67645B" modified="2008-01-15" version="1">MLNGILGRKIGMTQIFTEKGETIPVTVIEAGPCVVTQLRTKDKDGYEAVQLGFGEIKPRKVTKPIQGHLKAAGRLVRFMREVKTTDLNAHNVGDVVNVDIFQIGEKIDVVGTSKGRGFAGVVKRHGFRGGPATHGQSDRHRAPGSIGSGTTPGRVWKNMRMAGRMGNDRVTVQNLEVVKIDLERHVILVKGSVPGAKNGLVMVSRAAKATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B448</accession>
    <name>A9B448_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved repeat domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4951"/>
    <dbReference type="EnsemblBacteria" id="ABX07581">
        <property type="protein sequence ID" value="ABX07581"/>
        <property type="gene ID" value="Haur_4951"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4951"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_224995_0_0_0"/>
    <dbReference type="OMA" id="RDYTYTV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5014-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026466">
        <property type="entry name" value="Fim_isopep_form_D2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04226">
        <property type="entry name" value="RrgB_K2N_iso_D2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735436" evidence="3">
        <location>
            <begin position="21"/>
            <end position="3394"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="3098"/>
            <end position="3193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="3394" mass="348909" checksum="079A5B6721A603BE" modified="2008-01-15" version="1">MVAALLVGVLFVLQGSGAFAAPKPVQQAQTSAERPMAAPLLGSNDVLLSDMGGVGNADGSIAVNPVVAYNVTDSQYLLVWEGLETATGSLNLHGQLIDAVTGLEIGTNDFLIADDVDANDAYGKPQVVWNSVNNEYLVIFEGDSQVAVGLTNELEVYAQRVAANGSLIGTPLRVSQMGTDGVNTADAFEPSVTHNATNNQYAVVWYGDDLAGGRIDGEFEVYVQLLGFSGGNLIEVGGDVKVSDVGTTGSATIRPEDPNIVWNSAANEYLVVWRSDDSGTDGDFDVYGQRLTAALAEVGADDFLIANNANQDSFDVNVGYNPTNNLYLVLWSGDNVANSVYNVYGQIVSGAGAVTGGLLTLSSTNTGVSTDPVITYNSRDNQFIIAWMAPSAAGNTEREIFTQKINAATGARIAPNDVQVSDMGPNGNDNFFANGFIGIAYAGQTLNHTLVVWGGADNRDGQTTGESEIFGQLITPILNVRKTITSNITNLDAFDTLTYQIEVEHATIVEGADTVSLSLADAFNLNLTDDLPAQLNSPTIVSALVSDGANSTNVAGNLSVGSGDLATSTPFGLRYRSNGNNSEKLTLVLNTKVANTSVAGAIFGNTANATWSNTSLLGSVTGLTDSSANVNATMARAFTVSKSSLETEALINQDVTYHLDVGVIEGTTNSLQFVDTLPANTSYVPGSINVSNSNGMTINGLIANVSGQTLTINASSVVNPGNVDNGATADSDVFRLSYQVKVLDVPANVSGVVLTNSVNASASPGQVDNGNTHNLTIVEPFLDVSKTIVGVSTAVDAGDTVRYQIRVSHTAASTAQAYDVSVVDNLPAVLGSPVVESATISDGATNTDVTSNFTINGSGQLSTTTATNLNINTNGPNDQSLTIVVRGVVNNTVAPGATIANTANITWRNATSLQRSNYNDSSTAPNITVPAPFTVTKSVIAGSTPTIGSLVTYQLTVTVLEGTTSNIQLVDTLPAGMSYVTGSSSLNANGMTIATVTVSPVGQVVTFSTASVVNPGNSDAPNIMDTDSFTITYQARVNDVPGNVAGTVLANDVDATADGVAADNNNSVSVTVREPLLSIDKSITTSTAGVDAADTVRYRIEVFPQAASNANAFGLNITDDMPAALQGTVIESATISDGATNTDVASNFSINGSGDLVTLTPVDLALNTNGPSDQVLVIVMRGTVRNTVNPGGTIANAATVVWRNSENLQRASYTATDLAPSITIPASFSVTKTVAAPGTNVAVGATVTYRLSTTVIEGTTNNLQWVDTLPAGMSYVPGSATVETANGMTIPSLNVSLSGQVLTIGASSVTNPGNVDNAAAADTDSFTITYQATVNDVAGNVTGTVLTNDVDATANPGLSDNNNSASITVVEPLLAIDKALTTSAVGVDAGDTVRYRIEVSPQATSDSNAFDLNISDDMPAGIINMVIESATISDGATNTDVASSFSINGSGDLVTLTPPDLLLNTNGTNDQRLTIVVAGQVRNQINPGGSIANAATVTWRNSAGVQRASYTATALAPTITVANNFSVTKTVVAPGPEVGAGATVTYRLSTTLIEGTTDNIQWVDTLPVGMTYVPASAVIENANGMTVNGFAANISGQVLTISTSSVVNPGNVDNAAVADTDSFTITYQATVAGNATSGTLLTNDVDASADPGLSDTNNQVTVTVVEPELNISKTINSVTTGIDAGDEVRYFIKVQPTAGSGANATSVMITDTLPSQLTATSILSATISDGATTTNVAGNFTIVGGQLRTTGNLGLDLNTNGANDQVLTLMVRGLVADSTTPLSTINNTADLTWRNPGGVFNANYNDSATTPTINVASTWTVGKFIVPPITQVSIGQVVTYTVSTTVIEGTTLNPVWVDTIPTGMSYVPGSAQISNANGVTINDFSVALSGQTLTISATSIVNPGNTNNAGNVDIDTFLMTYQTVVGNVAGGTVLTNDLDSSASPSLVDNNNQVSVTVVEPTLSVVKTITTATGGVDAGDTVRYQIRVAHVPSSNNNATSVLLTDTLPLQLQNLTLVSAIVSDGATSTNVSGNFSLSGGVLRVTGNLNLLIDTNGSNDQVLTVIVQGTVRDLITPDSTIDNSATTTWSNASGVSRPVYTATGSAPTITAPSVWSVTKAISPAVSTVSPGQVVEYTLTTTVLEGTTTNPRWVDTLPVGMSYVAGSAQVLDANGMTINGFSANVSGQTLTIAASSVVNPGNVNNAAATDSDSFVIRYRAMVDNDVSLGTTLTNDVDATADPSLSDNDNSVSVTVREPDLTLSVAETSDAQLEAGDPITFVVTVNNPAGANAQDANTVAITSSFTSNLSNLNIVSAQQTGGATGGSFTIVGNNLQTNTPASMPIGSQIVLTISAEVNNTAAPASLAGMQSGVTWRNAADVSLPRYSKTDSIDASIASFFTVTKAIVPAASTVSAGQTVTYTLEVEVIEGSTSNIVLTDTLPVGMSYEVGSGAILSNGGITLNNFTVTSVGQTVIFRVDPATNPGSYPGDGLDTDNFSLVYRATIGQNVPSGTALTNNVDATASPNLSDNDNSVTVTVVEPDLNINLSKLTADGGVDAADRIRQQLVISHTTNSLASAYDVDLNVDLPASFGTPTLISAIVSDGATSTNFSGNLGFDANGDLINTGNINLLINTNGNNDQRLTVIVEYTLPNSINQGATASSEGSITWKNVSGSQLPSFTADSNVLDYSVATSFALEKAVANTSIASTVGNQVTFGEVVTYVLTATVLEGTTNNLSFVDSLPVGLTYVAGSASVANANGMTVNGLTANLSGQTLTIAASSVVNPGNVNDADTIDSDSFTITYQATVDGSSSVVRGAKLLNSVNGSADPSLTDTVNTATVDVAEPTLTIVKAVDDSTPDFGQVLDYTLTIEHTAQSNSIAYDLLVADSLPTGLSAVAGSLSVISGPAPTSFVINGSTIEATFASFATGSTTVLGYQARVASPPALAIGASLVNEVDLTWTSASGTVNLERSYNASDDVTVTLTSVDLAISKQVTPSVATPGTPVTFTIHLTNTGNLQTSNIVLTDIVSPLLTNVNVSSQGLTITDTGANPSYVWTVNDLPAGASGSIQISGIISPSLASDTTLINNVSVSDDIDQLLANNSASAIVALVVPRISFSLNNYEVVEATGSATVTVQLNAPNPNSAVQVTFATSNGTATLSDYTPVTQTLTIPQGQTSVQVIVPIIDDSTYELNETILLSLTNPAGTAFGTPITSTITIINDDRALVFIPMATKPASVDVVVDSIQVLNGTVRVTIRNTGSEPLSGGYWVDAYINPFQAPTAVNQPWNSISLFGMAWAVPTNAPVLAPNATLTLISGGQYYRSDLSFVPPGQLSAGSRIYAQADSFGLTNYGAILETHEINGGTYNNIRGPYIVPANTTLVFDEQRPSTPEDLTGVPERPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B481</accession>
    <name>A9B481_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4984"/>
    <dbReference type="EnsemblBacteria" id="ABX07614">
        <property type="protein sequence ID" value="ABX07614"/>
        <property type="gene ID" value="Haur_4984"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4984"/>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_715403_0_0_0"/>
    <dbReference type="OMA" id="FRPTMKP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5047-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="330" mass="35285" checksum="9BE52C9DD37877B3" modified="2008-01-15" version="1">MTLSHLATEDVFVVERNDADFRAGQGMTKGLGIVFRKFRKALFGKPNSDRADTEGQFNVQYPEERLVLPEAYRNMPILLYDDATGHELCTSCFQCERICPPQVIHITQAKDPATGKPVPAAANFVLEYDTCMSCGYCAEVCPFDAIKMDHDFELSTGNHPELDVNYDRLLRPISYYEAIAPTMWSDVKEQAMKKLQNNIKRRPGAIGRDHGQKVKGGAAVAVAATPVAGAAPAAAAKPRGPVAAIGKNMPEEKVAKLISIRAANAAKRGGGDAGAAPVAEAAPIVETVVDTPAASAAPSGPVAAIGQNMSEDKRAKLEAIRAAKRAQRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4G8</accession>
    <name>A9B4G8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4350 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0073"/>
    <dbReference type="EnsemblBacteria" id="ABX02725">
        <property type="protein sequence ID" value="ABX02725"/>
        <property type="gene ID" value="Haur_0073"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0073"/>
    <dbReference type="eggNOG" id="ENOG5032W7Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_713476_0_0_0"/>
    <dbReference type="OMA" id="MGWLMRR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-74-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025646">
        <property type="entry name" value="DUF4350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14258">
        <property type="entry name" value="DUF4350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4350" evidence="1">
        <location>
            <begin position="41"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="388" mass="43589" checksum="9F9A8A3AAE2148E4" modified="2008-01-15" version="1">MNSKVKFFAIFIGIVALSFFLFRSCDPQARNLRPGSMYNQGGDGTAALQLWLSKIGYQTESFEYRDFDELDQTIDTLLVIKPSDTNNWRKEEIDAVLAWVEDTGGTLIVADDQQNGLLTRLDLTVTRIEALEMVSTSDTSHALVNPIVNGLQGYQTISYFERVRPNSQVIVGSEAQPTTLGISRGRGMIYASTNIWLFTNAGLFYESNAKIILNMVNRMPAGSVIAFDEVHHGRALPPKAAPVPAQPYSPLVAAMVYSAMVVGLWALLSGRRFGQIVPSRIDLMRRNSSEYVQSMANLFQRGRQAEHMQAHYKTYLKRRVAKPYGINPKLDDQSFLSEVQRYSDTIDRNHLAHLLNHLSQPNPSEATILALVNDIDRFINLWEQQGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H1</accession>
    <name>A9B4H1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spore coat protein CotH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1492"/>
    <dbReference type="EnsemblBacteria" id="ABX04136">
        <property type="protein sequence ID" value="ABX04136"/>
        <property type="gene ID" value="Haur_1492"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1492"/>
    <dbReference type="eggNOG" id="COG5337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034916_0_0_0"/>
    <dbReference type="OMA" id="WDNNEAL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1514-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="PTHR40050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731877" evidence="1">
        <location>
            <begin position="21"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="564" mass="60799" checksum="50B97A2D66E555FA" modified="2008-01-15" version="1">MKFWRWLCLLAIGLNLAACATSTPTTVVTAEPTAEDAAVTRPVGWNEASHGDSAEPNYAVVFAQNKVNQLTITIDSASWQAMQDNMTELLGEPGSRQMGGGFPGGVFTDTAGLPMRPGGAFTDTLGMPMRPNGAFTDTAGMPMLPGGAFTDTNRMPGGFGGGMPNMGNFSIENPMWVTATLTFEGQTWTNVGVRYKGNSSLMSAWNSQQANLPFKIDFDEFEKSYPEIENQRFYGFKQLALSNNLGDATAMRETLAYDVFEQMGLPAAETATYEVLINHGDGVESLGLYTAVEVIDDTAIARVFGDDSGNIYEGDGSAASFAAGTKDAIEESFQKENNDTTDWADVEALYDVLHSSERTSDPAAWRAKLEAIFDVPSFLKWLGVSTLLEHWDTYGAMTHNYYLYNNPATGKLTWISWDHNFVLGAMGGGGMRGNQAIPNVANPAVGAGNQMPNNANAGGMRGPGGGFGGQNNTFDKASITSDWPLIRYLLDDPTYYAAYIAALRETSNQFDAEALVQKYTALAATISPSAAQTISLDDYNSAVTTLMERIKTRSADLKTFLATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4M1</accession>
    <name>A9B4M1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_1543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1543"/>
    <dbReference type="EnsemblBacteria" id="ABX04186">
        <property type="protein sequence ID" value="ABX04186"/>
        <property type="gene ID" value="Haur_1543"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1543"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_14_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1567-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="17"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX04186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="206" mass="21385" checksum="A0BF063CAB298030" modified="2008-01-15" version="1">MTAQATANDGQARGNLGQLILATGAFAVCFAIFGSVSAMMPTIKTDLNLTPVQVSVALALPVLLGSLGRIPLGMLTDRYGGRVVFSAVMAGSIIPSLGMGWIDTYNQLLIAAFGCGLALASFSVGVGFVSGWYPPQRQGFALGVYGAGNAGQSLAAFGAPVLAANLGYQWGFWVFSALTVVWLICFMLFARNAPRQGPAKSLSQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4Q7</accession>
    <name>A9B4Q7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NMT1/THI5 like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1579"/>
    <dbReference type="EnsemblBacteria" id="ABX04222">
        <property type="protein sequence ID" value="ABX04222"/>
        <property type="gene ID" value="Haur_1579"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1579"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_1_0_0"/>
    <dbReference type="OMA" id="YVMAMYQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1603-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002731880" evidence="1">
        <location>
            <begin position="24"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="49"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="342" mass="36812" checksum="F7FF0566E0B4E8C6" modified="2008-01-15" version="1">MRYRRILAVVGLFFLAACGGQTATPTAVTGNDQAKPLTKVTIAMPYVPNIQFAPFYLAKTQGYYEAEGLDVTFDYQYETDSVQRVANGSVQFGMAGGDSVLLARAQGLPIMTVATISQRSPIVFYSKAELNIKTPADLKGKSVGIPGRFGASYIGLLALMYSNSLQESDLNIQEIGFAQVQALSEDKVQVASGYGNNEPIQLAEAGVKLNVIRVSDSFALTSDGLIVSESLIKEQPTVVMGFVKATLKGMSATIADPTQAFNSSLREIPELQAADDATKALQQKVLAETIGYWQSDSTAKYGLGFTDQATWQATHDFLRQQNILKQDVAVGESFVNGFIATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4R1</accession>
    <name>A9B4R1_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1583"/>
    <dbReference type="EnsemblBacteria" id="ABX04226">
        <property type="protein sequence ID" value="ABX04226"/>
        <property type="gene ID" value="Haur_1583"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1583"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136060_2_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1607-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="127" mass="14455" checksum="33607084DE8C3B8A" modified="2008-01-15" version="1">MMSNAHALVTQFWQLMQTNDFVAVGSVLHDEYILDWPQSNERIRGRAAFAQMNQEYPAAGAWQFTINRLIASETQACSDVSVTDGQVEARVISFFTIRDGLIINQVEYWPEPYPAPANRQHLVEPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4V8</accession>
    <name>A9B4V8_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_3043</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3043"/>
    <dbReference type="REBASE" id="16536">
        <property type="entry name" value="M.HauORF3043P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05681">
        <property type="protein sequence ID" value="ABX05681"/>
        <property type="gene ID" value="Haur_3043"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3043"/>
    <dbReference type="eggNOG" id="COG2189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024927_5_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3075-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040843">
        <property type="entry name" value="RAMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18755">
        <property type="entry name" value="RAMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RAMA" evidence="9">
        <location>
            <begin position="267"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX05681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="375" mass="42397" checksum="9F9DAD5143274AD4" modified="2008-01-15" version="1">MADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDWDSFRDFAAYDAFTRAWLQACQRVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWIKRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRHLNDDKQMRSDWEFPLCTGNERLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERDPSYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPNLVATLLADASLRMSDGTRGSIHKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVRRLREQTPSADDLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A9B515</accession>
    <name>A9B515_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ordered locus">Haur_3516</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3516"/>
    <dbReference type="EnsemblBacteria" id="ABX06152">
        <property type="protein sequence ID" value="ABX06152"/>
        <property type="gene ID" value="Haur_3516"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3516"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031507_1_2_0"/>
    <dbReference type="OMA" id="VEMGANH"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="33"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="139"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="355"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="141"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="489" mass="52325" checksum="6290A3340A428FB3" modified="2008-01-15" version="1">MLTLQTVVDGVKIASEPRLQLPAALANLPIRSACIDSREASVDGLFVALQGERVDGHDFIAAAAARGVRAALVQRGRLADPSQLGLDRPFVLLDPDQGQIANEAPANAFFLISVDQTLTAMHRLATRYRQQQDLVVVGITGSVGKTSTKEVLAAMLAPTMRTHKSPRSYNSENTLPLVVLGIEPEHQIAVLEMGIYNKGDLALLTTIAQPQIGIVTNVGASHLERMHTIENVAEAKSELVQALPADGWAILNYDDQRVRAMQQVTKAQVFTYGLDPEADLWADNIESRGLDGIGFDAHYRGEQWHIKLPLIGLHSVHTALAAAAVGIVLGLSWDSLIQGLRSSAQLRLLSYPAVGGATLIDDTYNASPVSCIAALNLLAELQGRRIAVFGDMAELGPHDESGHRLVGVRAADVVDQLYVVGEKARWIGEEAIEVGLPAEQVHVLPDKAALIAALQSTLQANDYVLVKGSRAAAMEAVANALQVRPEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B557</accession>
    <name>A9B557_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3558"/>
    <dbReference type="EnsemblBacteria" id="ABX06194">
        <property type="protein sequence ID" value="ABX06194"/>
        <property type="gene ID" value="Haur_3558"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3558"/>
    <dbReference type="HOGENOM" id="CLU_1452587_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3595-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="187" mass="21250" checksum="F3C235FCDEA6FCDD" modified="2008-01-15" version="1">MRYWWLLIVLIGCIQTDQTPPAANQLTSYRLYFFEHKVLSQQKDAHIAANQEWNILRDPDLSQASYVLSDSAIVEYNWPKQTLVLQNPWAEGNQKTPLWMSEGTTLVVFNGQIIRAYQRELSITSKYIAPETAVMYHELQANVGDTTKLSYRLMQTGATSPAAIVSDDGAMAEAVKQHFRQLGKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B573</accession>
    <name>A9B573_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_3574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3574"/>
    <dbReference type="EnsemblBacteria" id="ABX06210">
        <property type="protein sequence ID" value="ABX06210"/>
        <property type="gene ID" value="Haur_3574"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3574"/>
    <dbReference type="eggNOG" id="ENOG502ZP62">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959361_0_0_0"/>
    <dbReference type="OMA" id="HTYLTIV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3613-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="33179" checksum="B87C85661328F0AE" modified="2008-01-15" version="1">MKYLRRSIIALVLYLAAFFNIERLDFQGENVIDLRSFVYVLGLAAILTTIVLPFFRQRRLLVALTYWGAIYAIIRLAFFNDVSFVGVDIYLSLTELVFLLVGVRFAHQVAIDLYDFEQAVINITLPQVNRQIRPLNDSNDEIQTEMVRSRRHRRPMSVLVIKPDPQSVNLAIHRSVEEVQKSMMTRYVVTSLTRVVADVMRRTDMIFEQPSSNQFIVMSPETNAANSVSFAERIKAAASERLGVDVLCGIASFPDDALTFDELIREADTRALRQLKGVKPQDTRSTVQTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A9B583</accession>
    <name>A9B583_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3584</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3584"/>
    <dbReference type="EnsemblBacteria" id="ABX06220">
        <property type="protein sequence ID" value="ABX06220"/>
        <property type="gene ID" value="Haur_3584"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3584"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_3_1_0"/>
    <dbReference type="OMA" id="LYRPKMG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3623-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="362"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="628" mass="70577" checksum="F8FE4DA37EC05698" modified="2008-01-15" version="1">MCGICGIVYFDRSRTAERPLLEALCDNIHHRGPDQNGFYLNGPVGLGSVRLSIIDVAGGKMPIANEDGSIWIVYNGEVYNFTELRPRLEKAGHKFETHSDTETIVHLYEEIGDEFPKHLNGMFACAIWDDRRQRLVIARDHVGIKPVYYANLGDRLVFGSEIKAMLDTGISREIDPIGLHDYLSLNYVPGPNTIFKAIKKLQPGHMLTYEAETNAVEVKQYWDIPRVVSPHFKITDDVETDLLNLLRTVVQDQLISDVPLGAFLSGGVDSSLVVALMSEVTNQPVKTFSVGFAEKSYDESPYARIVAERFRTDHHEIIMNPDAQATVDAMVKYFDEPFADSSSVAVYAVSELARQHVKVALSGDGGDEVFGGYATYQADKIAALYRRLPQAIGGGLVPSLVNMLPTSDGKVSFDFKAKRFVQGGMLAPLPAHAAWKAFMSESMKEQLYAGSAILTKQRPTVDLLQGYYDAYNADDVLNRLLYVDSKVQLADDMLVKVDRMSMAHSLEVRVPLLDTRLVEWMAKLPSHTKINGMKLKYLLKRVAAKVLPAQILERRKAGFSVPIPQWLKTDLRPLVNQKLSVEALTEQGFFNPQYIATMLSDHWAGRHDYSRQIWNLLMFSMWYERYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5F2</accession>
    <name>A9B5F2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA polymerase, sigma 54 subunit, RpoN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0125</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0125"/>
    <dbReference type="EnsemblBacteria" id="ABX02777">
        <property type="protein sequence ID" value="ABX02777"/>
        <property type="gene ID" value="Haur_0125"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0125"/>
    <dbReference type="eggNOG" id="COG1508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020569_1_1_0"/>
    <dbReference type="OMA" id="VTTQKFM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-128-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="10">
        <location>
            <begin position="109"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="9">
        <location>
            <begin position="319"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX02777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="461" mass="52580" checksum="E8D60E097361B254" modified="2008-01-15" version="1">MEFRMGMSPEALAQQAMSTKASPALIALNNMLVLSTHELQQLIQQELEENPALENVDLEPDETCSRCGRPLIEMLCLYCVHEDQRLAEAERGDYTAAGEDDEFDPLMMVATPAQLSEVLLRDLRASLPEQDYFIAEYLVGCLDDQGFLDANTGDIAATLTIDEERVIAVLLKLQDIAPVGVGARDVQECLLLQLRRLDEEDVRHPYVERVITEFWNDLAEHRYGAIAQALNAEYDAVVEVREFIREHLRPYPLALSGEGSARTNYIMPDVIIRENEGKLEAEVLMSDRSFLRINPLYQSLVKRGREAEAEMSSEDRDHLSQYVARAQMFLTNIRQRRETIRRISEFLIETQEDFLRQGVRFLRPMTRAEVADGIGVHESTVSRATANKYVQLPNRSVIPFSHFFTASLNVKDVLLELVQNEVRPLTDQELVELLAERGFEVARRTIAKYRNQLNILPSTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5H4</accession>
    <name>A9B5H4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartate/glutamate/uridylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0147"/>
    <dbReference type="EnsemblBacteria" id="ABX02799">
        <property type="protein sequence ID" value="ABX02799"/>
        <property type="gene ID" value="Haur_0147"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0147"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1213478_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-150-MON"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="228" mass="24057" checksum="6CE964B22EB44F21" modified="2008-01-15" version="1">MTHVIKISGYEVDHADSLQTLISALSSIDDQVVLIHGGGSILPRVLNAIGGTNHPAAAEIAAMALRGGINPRLVAALTQHHLQAIGLCGSDLELMYLLPKSDEPIVRFEVLHYLLEQAWLPVLAPLAMESATGAVKLLNADTAAQMIASALAADQLTYIVQTPGVYASGRRISGISGRQCERYIKQGAFDATYTSVVKAASLAAPHVGRVRITDLNGFLDGVETVVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S2</accession>
    <name>A9B5S2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1662"/>
    <dbReference type="EnsemblBacteria" id="ABX04305">
        <property type="protein sequence ID" value="ABX04305"/>
        <property type="gene ID" value="Haur_1662"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1662"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_4_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1686-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="173"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="290" mass="31789" checksum="EF69BCBD019D7652" modified="2008-01-15" version="1">MSNSASDSAALQAQIAELQAQLAHAQRQAELFENLVKRLPIGIDLLQREDPNDPTSLRLIFTNGLMPNAPIDMRLHVGKLIKDIFPDVPPMVFDRYQHALDSGEMVHLNELTVKVPDIGVRIAQLSAIPLTNDILCIKVADITEQKQVLEAQRHMMEQQAIINSQQEALADISTPLIPITDSVVIMPLIGAVDTRRAQQMMETLLHGISHMTARFAILDITGVPIVDTQVAHVLIQAAQSVRLLGGQVILTGIRPEVAQTLVGLGVNLNDLIVRGNLQSGVAYATLERYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S7</accession>
    <name>A9B5S7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1667"/>
    <dbReference type="EnsemblBacteria" id="ABX04310">
        <property type="protein sequence ID" value="ABX04310"/>
        <property type="gene ID" value="Haur_1667"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1667"/>
    <dbReference type="eggNOG" id="ENOG5030IRU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126433_0_1_0"/>
    <dbReference type="OMA" id="VFHISRG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1691-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="118" mass="12592" checksum="73687D66DED06428" modified="2008-01-15" version="1">MNIVLWIIQGLLALVFGGAGAFKLIQPKDKIAAQLAWAKDFTPNTIKLIGGVEVLGALGLILPWLTGIAPILTPLAALGLALTMFVAGLVHARLKEYPMVGINIVLLSLALFVAYERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5W8</accession>
    <name>A9B5W8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3124"/>
    <dbReference type="EnsemblBacteria" id="ABX05761">
        <property type="protein sequence ID" value="ABX05761"/>
        <property type="gene ID" value="Haur_3124"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3124"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_729144_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3156-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="263"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="379" mass="43142" checksum="00BC5AEA23901C84" modified="2008-01-15" version="1">MQPRRWIHRLVLAGTSLIFLVLLVLLGFNLQTLGMATRFFTLDGGIWNPTQLEREILRLRVIANEISMGTPNLGNEFVLRRNLVGSRINVLSDFYRVEHEDQRSMLERSSFEVIKREFFTLENQTRFNISDHSVQALIPVLVNMESNARVMVNERRQIVDRASQFQRQSLERLRVTLLFMLGGILIQVPIFFLLTRRRFDTTLQKAYSTLQERSTALEQSQRELASSHTHAQQQNEALQKTLADLEHSMAERSALQTTVQQMQFPIIPLRNRMAIMPVIGNLSAERIKIATDSAGHYVEAKRIKILLFDITGVSAIDQAAAASMQQLLQMLRLLGCEPVLVGVTPAVAEELVHTGLIQQNLQTYANLQQAIEVTAKTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B670</accession>
    <name>A9B670_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Neutral metalloproteinase</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_3645</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Extracellular zinc metalloprotease.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3645"/>
    <dbReference type="MEROPS" id="M04.018"/>
    <dbReference type="EnsemblBacteria" id="ABX06281">
        <property type="protein sequence ID" value="ABX06281"/>
        <property type="gene ID" value="Haur_3645"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3645"/>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008590_5_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3684-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023157613" description="Neutral metalloproteinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="220"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="368"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="532" mass="56660" checksum="D7E46CCD6D1E7EF9" modified="2008-01-15" version="1">MVRKRLITVAALLGLVGAVFGSAVSTGAQDYDKVRGQLIRTYREAEAKGVRPDWVTAAVDTSLNHFAGKGANSANLQVRGVDQDDLGINVRLDQTYAGLPVFGGQVIAHLDNKGNVTQESGELFAVDGIDTSASLSSAEAIKIAQSQVKYDFNAKNASGTEVSSELKILPREGKDSVIVFQVSLHIEDGSEATAHHEFFINAKTGETELYYNDMDGVNATGTGKSLYSGNVSITTDLVSGVYYLRDNSRGGMYTTNMNNRTTGGSTFTDADNVWGTNTTANVQSAGVDAHYGAQLTWDYYLSSFGRRGIDGNGFRVLSRVHYGNRYNNAFWNGSSMTYGDGDGTTFRPLVSLDVAGHEITHGLTEKTAGLIYSNESGAANESFSDIFGTMVEYSSGTGDYLIGEDIYTPATAGDALRNMSNPAAEGDPDHYSKRYTGTGDNGGVHINSGIQNQVFYLLAQGGTNRTSGLAVTGIGRPKAAAIFYRALTVYLTPSSNFKAVRTATLNAARDLYGASSAEYNATAQAWTACGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B675</accession>
    <name>A9B675_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3650"/>
    <dbReference type="EnsemblBacteria" id="ABX06286">
        <property type="protein sequence ID" value="ABX06286"/>
        <property type="gene ID" value="Haur_3650"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3650"/>
    <dbReference type="HOGENOM" id="CLU_200481_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3689-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="70" mass="7514" checksum="487A9D917F7D618A" modified="2008-01-15" version="1">MKELIAQLVEKANLNEEQANKAVEVVKGFLGDKLPEGLRGQVEGFLTGENIMDVADKAKGLLGGLFGNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B794</accession>
    <name>A9B794_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3741</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3741"/>
    <dbReference type="MEROPS" id="C39.005"/>
    <dbReference type="EnsemblBacteria" id="ABX06377">
        <property type="protein sequence ID" value="ABX06377"/>
        <property type="gene ID" value="Haur_3741"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3741"/>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="CACVVIA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3783-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="172"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="483"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="517"/>
            <end position="524"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="720" mass="79406" checksum="1350C40631415EF6" modified="2008-01-15" version="1">MLKRWLASFKRRRVPVLLQLSAIECGAACLAMVLSYWGRATSVAEAREVCRPSRDGLSAQTIAAAGRHYGLIVRAFALQNLDFGSLQLPAILHWNFNHFVVLEQWSPRGATIVDPALGRRFVELSELDQRFTGIVLSCQPGPNFEQRQRSNTNQWRLIRSTLLAKPSLLGQIIVASGLLQLVGLALPLLTKSLVQQVTLPSFEVLLGRVLIGLGLIISIRFLIQYMRSLLLIQLQLRFDTDLSEHFLSHLLRLPLAFFEQRSSGDLLLRLTSNSTIRELITNQVLSVVLDGGLMLVYGGLLFWQSGSFGLTVAIIALLQVAIIWLTQGRLRPLVETDLLEQSEAQSYLVELLSGITTIKAMGVEHYAFGYWQNLARRQRNTSLRRQRLSAIVDSMLGTLQTATPLILLWVGLREVHQGQMDLSTMLALNAIGTLALAPLVTLISQGQRLQLLTSYLERLNDVLMAQPEPDGSFAPEANLQGAIRLENVSFGYNPHTAPILRDISLQIAPGQKVALVGRTGSGKSTLAKLLLGLYQPSSGQILIDERPIEDYDRQALRQQFGVVLQDAFLFSGSIRQNINLQRASLPAAQLIAASQRAGLHSDIVSMPMGYETRVGEAAGGISGGQRQRIALARALLRQPAILILDEATSQLDTLTEQIVEQQLNQLNCTRIVIAHRLSTVKNADLIIVLDRGQIAEQGTHSELVGTNGVYAKMVLNQQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E3</accession>
    <name>A9B7E3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06426">
        <property type="protein sequence ID" value="ABX06426"/>
        <property type="gene ID" value="Haur_3790"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3790"/>
    <dbReference type="HOGENOM" id="CLU_905429_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3832-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="307" mass="34776" checksum="8CFC5E7340E6BA0E" modified="2008-01-15" version="1">MQLAVSAKPETPLQPYVVSADYAPGTLIKQQTLELPIYHSPEQKLYELEIAGFRVEDADPETALRQAVPVLKALVNLARLPTYVFIARRSRQVYPIYSIGDDVLATTPGGPVFRHVELAKVREYLNEYLHLTGVLGRPGASDKLHVRGVDAKTLGLIRPTCYFKKRITGQTDFWAPVFANEQELYTFAASKRHAVALSEPNALMGLHALVAKALIKDKRLFHEHDLRVDRMFAEPWEIWKKDLTAVNEPIVLGDVSLNVYQYGPTWLAVEKRRDRDELRPSLFLGENLYDLTARVTADFKRRGLIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7E5</accession>
    <name>A9B7E5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">Shikimate kinase</fullName>
                <shortName evidence="13">SK</shortName>
                <ecNumber evidence="13">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">3-dehydroquinate synthase</fullName>
                <shortName evidence="14">DHQS</shortName>
                <ecNumber evidence="14">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">aroB</name>
        <name evidence="13" type="synonym">aroK</name>
        <name evidence="16" type="ordered locus">Haur_0266</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="function">
        <text evidence="13">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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    </evidence>
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    <sequence length="539" mass="58050" checksum="52EE57BC1FD03A7F" modified="2008-01-15" version="1">MQPSGQSIALIGPSGAGKSTVGVGLAQALGWRFIDLDQLIIERAEKSISDIFSQEGEAGFRERETAALVQALQTDQAVIACGGGIVLREINRQLLREQAWCVYLTSAISTLVKRLTADQANPRPLLASDINEQLVIQLAERLPLYSTLANWTIQTDGLAPQIVVEQLIRAWGLVGKPQVSEVFSSFNSRYYVKSGALAALPNELANLGLTGTCWLISDSHVGPMYAPTLIQALENSGFSCQRYDIPAQEASKSWQQAGELYTWLLENGVQRGDTVLALGGGVVGDLAGFIAASILRGIAVVQLPTTILAMIDSSIGGKTGINHPRGKNLIGAFHPPRLVLIDDAVLSSLPRRERAAGWAEAVKHGVIADAQLFADLEQAGASLNDVPAKITSDLLVRSAAVKIGVVNRDERETGERMLLNYGHTLGQAVEAATQYKRYVHGEAVAIGMTFAANLAVQLGMWSSAEAERQRALLQALELPTALPRDLDIEATLAALNLDKKRAKGSVRWVLPTRIGHAQVESHVDPELVRKLVHELVEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7G2</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Haur_0283</name>
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    <organism evidence="1 2">
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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    </dbReference>
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        <property type="gene ID" value="Haur_0283"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0283"/>
    <dbReference type="HOGENOM" id="CLU_1701841_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-286-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="154" mass="17739" checksum="1448536FD19F4A19" modified="2008-01-15" version="1">MDSHWFTPDHQHYFQVGIDSYPHPVPVTNALRCLLFGFSQQDHPLVIHPLTFAEPNHFGTFTQRWMSPQMQGNAIAGWTGFMALRYLLGYFSQWVLLPPAIRYQAWHPTARTVTPPVQVIAAIRAWDVGWEHQLDNLLPRIETLRHPQYAALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7I1</accession>
    <name>A9B7I1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0302"/>
    <dbReference type="EnsemblBacteria" id="ABX02954">
        <property type="protein sequence ID" value="ABX02954"/>
        <property type="gene ID" value="Haur_0302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0302"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1719835_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-305-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="4">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="4">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX02954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="152" mass="17013" checksum="7EEC4B0C160E30C1" modified="2008-01-15" version="1">MSSAILWISIAVVMGLMLWSWSKRSERPSSMINFNQPPIKPTQTPSFDSAKLDQAQIQLLLSQGKKLEAIKHVRLQTSLGLKEAKDYVEAIERGQSPLSPVVVEPPVLQLPEDLLREAQIVAQQGNKIQAIKMVREATKLSLKEAKDLVESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R6</accession>
    <name>A9B7R6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="2">2.5.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.54" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1801"/>
    <dbReference type="EnsemblBacteria" id="ABX04444">
        <property type="protein sequence ID" value="ABX04444"/>
        <property type="gene ID" value="Haur_1801"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1801"/>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062599_1_1_0"/>
    <dbReference type="OMA" id="YRNIPEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1829-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="285" mass="30120" checksum="47657B8E09E101A1" modified="2008-01-15" version="1">MSNANASTKPAPYRLAARTDAHQATIVDLGSVKIGGGQPVVMAGPCSVESESQLLNTAYAVAEAGAHMLRGGAFKPRTSPYAFRGLGEAGLKILAKARAETGLPIITEALNTADLDLVAEYTDVIQIGARNMQNFALLEAAGRTGRPVMVKRGPAGTIEEWLLAAEYVLATGNPNVILCERGIRTFENATRNTLDLNAVAMAKHRSHLPVIVDPSHGTGKWYLVAPLALAGLAVGGDGLMIEVHHDPDHASSDGPQSLNHEHFADLMEKINQQSAQPVAREVGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7U7</accession>
    <name>A9B7U7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1832"/>
    <dbReference type="EnsemblBacteria" id="ABX04475">
        <property type="protein sequence ID" value="ABX04475"/>
        <property type="gene ID" value="Haur_1832"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1832"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_979241_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1860-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="32576" checksum="965E5B71617AB390" modified="2008-01-15" version="1">MLDNAEPILLLAEDAQTDATIVQVIAQRCGWQVVWLKSLFAMWQYCVSMLDREQPPLNCVIMLDMKMPDPAYRNLEGSVLATWLSHAMHEQRLQQAPIFGMTTDKTLHREWEAKIAGCYQLFEKPLRPEHFQRLQQSLNNPTPPAIDGVDQIACEIIRKQHLDIMHTVIAAYQNQAAPSASTDWSLDELRVLLSHLTNSIYCPRHLQQQREQILERAGGLMQLQRSIRDFLTNQQLSTFELKILNRILQGVSQERIAAQEAIGRRKLEATIEHILVAFGLFLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7V1</accession>
    <name>A9B7V1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1836"/>
    <dbReference type="EnsemblBacteria" id="ABX04479">
        <property type="protein sequence ID" value="ABX04479"/>
        <property type="gene ID" value="Haur_1836"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1836"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_0"/>
    <dbReference type="OMA" id="RYVFGNK"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1864-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="5">
        <location>
            <begin position="5"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="325" mass="33194" checksum="545EB44121965E76" modified="2008-01-15" version="1">MASGVWVLIEHKNGEVGAISKELLGKGKEIADALGQAVAALVLGNNTASLVEQAFAAGASKAYVVDDANLAQYTTDGYVAAAKAAIEAHQPEVFLTGSSLQMRDFTGALAAELGVGLAPDVTNIGVEAGQLTAVRPSHGANVINSLSFGAARPAIASVRRQVGKPIAGAGAGEVVNVAMPAVNIRTKVRNVEQRTGAVNLADATVIVSGGRGLGSPENYEKLIPELARVMGGTHGASRAVVDAGWIAYERQVGQTGKTVAPKLYVACGISGAIQHLAGMRSSNTIVAINKDPEAPIFKVATYGIVGDINEVLPALTAEVKAKTGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9B805</accession>
    <name>LEUC_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="1">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM isomerase</fullName>
            <shortName evidence="1">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuC</name>
        <name type="ordered locus">Haur_3302</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9B805"/>
    <dbReference type="SMR" id="A9B805"/>
    <dbReference type="STRING" id="316274.Haur_3302"/>
    <dbReference type="EnsemblBacteria" id="ABX05938">
        <property type="protein sequence ID" value="ABX05938"/>
        <property type="gene ID" value="Haur_3302"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3302"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_0"/>
    <dbReference type="OMA" id="GCGPCMG"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01027">
        <property type="entry name" value="LeuC_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011826">
        <property type="entry name" value="HAcnase/IPMdehydase_lsu_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006251">
        <property type="entry name" value="Homoacnase/IPMdehydase_lsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01343">
        <property type="entry name" value="hacA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02086">
        <property type="entry name" value="IPMI_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000135734" description="3-isopropylmalate dehydratase large subunit">
        <location>
            <begin position="1"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01027"/>
        </source>
    </evidence>
    <sequence length="421" mass="44522" checksum="A2B587A90171DFF2" modified="2008-01-15" version="1">MGQTFAEQILGHASGRSDVQAGDMVVVNVDLVMMHDSLSPSIIETLHNELGAERVWDRDKVAVVIDHVAPAATVRQAEQQQQVRRWVAQQGISHLFDVGRGISHPVLIEEGLVQPGMLVVGSDSHSTGYGAAAAFGSGMGTTDIALALATGQTWFRVPETVRVNAVGNFQPGVSVKDFGLWAARTLRADGATYQSVEWHGVDFLSWRERMTLATLSIEVGAKAGIVAPTGLGAEHPVPEWLRVEADASYSRVVECDLSTLEPQVSVPHYVDNVVDLADVGRVAVDVVYLGTCTNGHYEDMAAAASILKGRRLAPNVRMIVVPASSESLHRAASDGTLATLLAAGATIGTPGCGACIGRHMGVLAPDEVCVFTGNRNFRGRMGSPGANIYLASPEVAAATAVTGYITHPRNVLDSTEQAVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8G8</accession>
    <name>A9B8G8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07632">
        <property type="protein sequence ID" value="ABX07632"/>
        <property type="gene ID" value="Haur_5002"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5002"/>
    <dbReference type="HOGENOM" id="CLU_1832422_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5065-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="140" mass="15654" checksum="E099CBA35D3B8BA9" modified="2008-01-15" version="1">MADWLVTEQQATSDLAAIIQSKDAMLARVAANDQRREVKGLILRSLVAEVIDAATLATLDRQRAKIPMAGAYTAEFWFAQLRAHRPHEAYARCEHRESHPVFAEWDARCPRCHLPLTKPPTVIPPQAEQTMLPFSTPTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I3</accession>
    <name>A9B8I3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5017</name>
    </gene>
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        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
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    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="hau:Haur_5017"/>
    <dbReference type="HOGENOM" id="CLU_066192_31_3_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5080-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="77" mass="8575" checksum="4822E4F7C0A34C88" modified="2008-01-15" version="1">MAIQIRLRHVLDDRALSMYAVAKGTGLTYPTVYNLATKPITRIDIETIDKLCAFLQIQPGELFVWTPDEDAAPLAAE</sequence>
</entry>
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    <name>A9B8I5_HERA2</name>
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            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
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                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
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                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
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    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
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                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
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    </reference>
    <dbReference type="EMBL" id="CP000876">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07649">
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    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5019"/>
    <dbReference type="HOGENOM" id="CLU_2232833_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5082-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
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    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="107" mass="11811" checksum="91F2E338659D3C61" modified="2008-01-15" version="1">MTPLDVNMTRRVRLAQVSRILQLAVIIREEESVDDDEAYTMAEALLDEVNATADDWGSHQPASPLGVIATAWGLALRRNGTVLTLVPADLTLLREAITAWEQQYHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8X6</accession>
    <name>A9B8X6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5162</name>
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    <organism evidence="2 3">
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            <taxon>Herpetosiphon</taxon>
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        <name>pHAU01</name>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
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    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07790">
        <property type="protein sequence ID" value="ABX07790"/>
        <property type="gene ID" value="Haur_5162"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5162"/>
    <dbReference type="HOGENOM" id="CLU_2617165_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5224-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="78" mass="8932" checksum="0CEFFA14936D3C92" modified="2008-01-15" version="1">MPAYPRYTDGAQPRPEEDSGGAYAYAQKLARSRRAKAAAKQRRRNEQGDEKALDARADLQPSRRSTYARDWTRNQFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Y8</accession>
    <name>A9B8Y8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5174</name>
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    <organism evidence="2 3">
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            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
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    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07802">
        <property type="protein sequence ID" value="ABX07802"/>
        <property type="gene ID" value="Haur_5174"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5174"/>
    <dbReference type="HOGENOM" id="CLU_1515910_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5236-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="177" mass="19691" checksum="DFC1D158923BD13E" modified="2008-01-15" version="1">MDESTLLPPADADARPIVTDHRTALTIRGIQADTAAQSVMITEYRSRLAPKTRRRHEVDLQGFSDFLTTVGVVIPVDDQEVSVLAHDPAAWHGITAGLISAFRTWMLTEGYAIGTINIRLATVRTYARLAHLAGVIPADTYSRIRALSGYRRRKLSNDIVCLYLSFGWHKPIEHVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A9B994</accession>
    <name>A9B994_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5281"/>
    <dbReference type="EnsemblBacteria" id="ABX07908">
        <property type="protein sequence ID" value="ABX07908"/>
        <property type="gene ID" value="Haur_5281"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5281"/>
    <dbReference type="HOGENOM" id="CLU_1400806_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5343-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="194" mass="22046" checksum="01578FF48E71929C" modified="2008-01-15" version="1">MNALILPEAERMRQALYAQITTTTSARDLHALARSLSAIDHAVALIKTQHPQVIDALSDDVVQRVLVHDGTRTYRVTVGHHPSGVAWACHCSGRRRGYKGTCVHMLAVSLWFAVERERQRQAQQYTAQHMLNDAITVYEDATERRMICEEQLAEAHRAEANAWQVVCERREDVARIERHAPPLIVPRLRERDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A2</accession>
    <name>A9B9A2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5289"/>
    <dbReference type="EnsemblBacteria" id="ABX07916">
        <property type="protein sequence ID" value="ABX07916"/>
        <property type="gene ID" value="Haur_5289"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5289"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5351-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="155"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="548"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="716"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="857" mass="96469" checksum="67978BB2CB8BD79E" modified="2008-01-15" version="1">MDIRTLIPPLVDAVLAVCPVYERATIATALERVLVGEHITLGNNTISMLFGQNNDFSNAKIMIGSIQAGHTISINVQPIIDKSFSDSTHTTDDDLKQARLLLSHIPLASLPKKGLLPKGSRIPFKDNPFFVGRDDMLLSIASTFFSCHSDAPIPTIGLVGMGGIGKTQLAVEFVYRYGSYFAGGIFWLSFAQPDSINTEVIDCYKYYCPQVIEDSAEKQIAYMKSLWMNPLPRLLVFDDCNEVDLLEKWRPQSGGCYVLVTSRRQQWPATVELSLLSVSTLDLAGSLDLLCLYRPDIREDQALGQKIAQKLANLPLAIHMAGSYLAHYKLKLEVYLAQLDQGITHESMKGRGTFHQPTNHESVNVTFNMALNNLSNHEPVNIISRLLLARTSWLMCNEPIPKTLLQSFAVDKGYDDLDIIDSIHKIVNLGLLEITIHTGFRIHELIAGLIKDKINDVSAYSDVERILGSKLASRSTWEEREELQWLIPHAYTIVQYALKRQDTNSADFMYGFARSLKRNSDYKASFMYHQKALAIRKKIFGDNHVNTAKSLNMLGMLCRKMANFNMAKEFYEQALEIYQRDLGDDHPTTLSTLNNLGYLLKAQGDLLQARECYQKVLKSRLINRGEEHRTTGTIFNNLGMVLKDLGDLKSAQEHVKKAVEIRKRICGDNHPDTLIALYNLASILFDLGLIEDSYKVAKSVLDDRCRILGDEHSSTASSLYQVGKLLHTKGEIDSALYNLEKALTIQKKLLGIDNPYTALTLQELGRLFQSKGEFELARHNIEYALGIQQRIFGLNHPAIGLSFHNLGELYEKMGNLQIAHFYYKQALEVRIHILGENHPSTIGTIDCLNRSSNWNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUR1</accession>
    <name>A9AUR1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1945"/>
    <dbReference type="EnsemblBacteria" id="ABX04588">
        <property type="protein sequence ID" value="ABX04588"/>
        <property type="gene ID" value="Haur_1945"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1945"/>
    <dbReference type="eggNOG" id="COG2764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_11_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1974-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="166" mass="18556" checksum="16479A88289325B4" modified="2008-01-15" version="1">MGHVPAGYCTVNPFIISNAATQLSAFLQAVFGAQPVEAAHTIDTDGLVLHSELKLGDSTLMVVDRKPDWPWTPSFLQVYVADLAQTLQTAVTHGATIVTEPTPMYGELFSRFVDPWHNLWWVYQSIGMDSWEATVPEGETWDTQSPELNYIHRTLLETMPRLGQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV40</accession>
    <name>A9AV40_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_0467</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0467"/>
    <dbReference type="EnsemblBacteria" id="ABX03118">
        <property type="protein sequence ID" value="ABX03118"/>
        <property type="gene ID" value="Haur_0467"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0467"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_3_2_0"/>
    <dbReference type="OMA" id="YVIATIE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-473-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="148" mass="15453" checksum="694AA4A55ECC0EE8" modified="2008-01-15" version="1">MASINKLLDKPGFGIAILRIVVGFIFFMHGLDKFNGGIEGTAGFLTSLGIPAPTFMAILLIATELIGGIMLMLGLFTRYVAVAEAIAMVVALVTVHLDAGFSSREGGYEYVLALIAASVALVLLGSGSLALDNLLSPRLTGRQITARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV43</accession>
    <name>A9AV43_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_0470</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0470"/>
    <dbReference type="EnsemblBacteria" id="ABX03121">
        <property type="protein sequence ID" value="ABX03121"/>
        <property type="gene ID" value="Haur_0470"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0470"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_0"/>
    <dbReference type="OMA" id="EHTMVRN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-476-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="221"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="286"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX03121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="432" mass="47753" checksum="52D4E1532C3DB8B5" modified="2008-01-15" version="1">MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDRLLATVQVGITLIGTFAAAFGGANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLIIGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLTTSSTVILTLIGQNKKPDSSVTEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEITRIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVSKMLTLFRRTGSHMALVVDEYGQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSWLIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLPNVGDHVTWDEYDVEVIDMDGRRIDKVLIKKRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVM2</accession>
    <name>PYRR_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional protein PyrR</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Pyrimidine operon regulatory protein</fullName>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Uracil phosphoribosyltransferase</fullName>
                <shortName evidence="1">UPRTase</shortName>
                <ecNumber evidence="1">2.4.2.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrR</name>
        <name type="ordered locus">Haur_3990</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AVM2"/>
    <dbReference type="SMR" id="A9AVM2"/>
    <dbReference type="STRING" id="316274.Haur_3990"/>
    <dbReference type="EnsemblBacteria" id="ABX06622">
        <property type="protein sequence ID" value="ABX06622"/>
        <property type="gene ID" value="Haur_3990"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3990"/>
    <dbReference type="eggNOG" id="COG2065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094234_2_1_0"/>
    <dbReference type="OMA" id="PIQPDFC"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01219">
        <property type="entry name" value="PyrR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023050">
        <property type="entry name" value="PyrR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000164848" description="Bifunctional protein PyrR">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PRPP-binding" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01219"/>
        </source>
    </evidence>
    <sequence length="178" mass="19720" checksum="00471E7A46D3B8A2" modified="2008-01-15" version="1">MTPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQVPVGELDIGLYRDDLHSRGPAPILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDWGRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDVQLSEIDAAQDSVVIVQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVR3</accession>
    <name>A9AVR3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron (Metal) dependent repressor, DtxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_4031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4031"/>
    <dbReference type="EnsemblBacteria" id="ABX06663">
        <property type="protein sequence ID" value="ABX06663"/>
        <property type="gene ID" value="Haur_4031"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4031"/>
    <dbReference type="eggNOG" id="COG1321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1918">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_0_2_0"/>
    <dbReference type="OMA" id="HGHPIPG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4073-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="223" mass="25144" checksum="DDEF75F966EC3417" modified="2008-01-15" version="1">MRITAGVQDYVKAIYTLQQEEAPVSNGRLASYFGFSAPTITEMLKKLESLELVDYQARYGVRLTEIGEKIALEMIRHHRLLELYLVQALGMSWDEVHDEAEVLEHVLSEALEERIAEYLGHPQFDPHGSPIPARDGSIPQRDSCSLALLELNQIARIVEVEDRDAARLRYLADLGLTPNNVITIIARAPFDGPLTLWVGAEQTQQVLDSRLATRIQVQIERSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW22</accession>
    <name>A9AW22_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0612"/>
    <dbReference type="EnsemblBacteria" id="ABX03260">
        <property type="protein sequence ID" value="ABX03260"/>
        <property type="gene ID" value="Haur_0612"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0612"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_9_0"/>
    <dbReference type="OMA" id="MHINVDE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-621-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="183" mass="20485" checksum="58CB9763AF4F2567" modified="2008-01-15" version="1">MAHFESIFSVRLCHPEDAPLLAPLISALATEEGVTPPEPEALEEIIRAMLTTGFSDFVIAERGPNEDEVVGCIQINYRLSTWAAAPYAYLEDFYLVPEARAQGIGTKLLDYACQRAEGKGCQNVQLDVREANKGAMRLYARYGFKVTNSMIWKRDKPECEHDYSAEINELVDHLRGNEETEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW88</accession>
    <name>A9AW88_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2098"/>
    <dbReference type="EnsemblBacteria" id="ABX04738">
        <property type="protein sequence ID" value="ABX04738"/>
        <property type="gene ID" value="Haur_2098"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2098"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_1_0"/>
    <dbReference type="OMA" id="MITARNG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2126-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="231" mass="24774" checksum="2FEEE0F29888901C" modified="2008-01-15" version="1">MSMATNEPSITMSTTRRSVAIVLYEGFTALDAIGPYEVLVSLPDTDVYFVADQQGPIYADTGQLALVATATWDELPHPTVVVIPGGAGTMQALAHQPLLNWLQTAAPTVEWMTSVCTGVFVLGAAGLLHGLQVTSHWTSREFIHQYCAATYTAERFIQQGNIITAAGVSAGIDMALFLAQQLSSSQTAQAIQLAIEYDPQPPFSGAGDFQQADQALIDETYTVLSKYRVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW89</accession>
    <name>A9AW89_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_2099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2099"/>
    <dbReference type="EnsemblBacteria" id="ABX04739">
        <property type="protein sequence ID" value="ABX04739"/>
        <property type="gene ID" value="Haur_2099"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2099"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_0"/>
    <dbReference type="OMA" id="IAMVICQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2127-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX04739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="261" mass="28729" checksum="640D664104A83B11" modified="2008-01-15" version="1">MKLTIHHVAVSVSSRQIVSNIDLAVQPGEIVGLVGPNGSGKSTILRTVYRMLRPSAGFVQLGDDDVWQMSPRTSARQTAAVVQESTHDVAFTVAKMVQMGRTPHKGFFAGDTDHDWQVTTTALARVQMLDCANRPFNTLSGGEKQRVLIARALAQEPQLLVLDEPTNHLDIHYQLDILELVRSLGITTLVTVHDLNLAAAYCDRLYVLSAGTIVAEGTPEQVLTPHWLRDIFLVNAVIQRHPVTNRIQLALFPLSHRHEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW92</accession>
    <name>A9AW92_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2102"/>
    <dbReference type="EnsemblBacteria" id="ABX04742">
        <property type="protein sequence ID" value="ABX04742"/>
        <property type="gene ID" value="Haur_2102"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2102"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062440_3_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2130-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="269" mass="29450" checksum="B5D22D99A332A254" modified="2008-01-15" version="1">MTTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGNDARSIAQRVGAEGLVIGLDNSEAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCRADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLIDGPDKTLLRQVVQRITDRVRNGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAALDWQRYCQTASRLGVFFSAITGFGVVGIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW96</accession>
    <name>A9AW96_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_2106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2106"/>
    <dbReference type="EnsemblBacteria" id="ABX04746">
        <property type="protein sequence ID" value="ABX04746"/>
        <property type="gene ID" value="Haur_2106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2106"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_12_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2134-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="934"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX04746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1927" mass="212452" checksum="2AFB9EF0B1468A60" modified="2008-01-15" version="1">MQQHEVEHFRLSPQQTHTWLVQPQSQQPLGTWLLVELTTPLRYERWQAGLNVVIERHEALRTRFEQIAGLKLPAQVLHNQTVVLHQQQIAESHQIAELAAPADAGLMQITLFEHGQQQWLGLWLAALVGDATSARLLLEELTQAALAPHELSASDELMQYIDAAEWQNGLLEAAESAAERAFWQTQAIKQAPHDLRGFARLTQTQPTRIKLNLPASSSIAINAWFTQHNVDLASTVLSLWRWLLSRSNYGQTPALALACDGRSYAELANAQGLFERYLPLLPNELAADQPIAEAITTLAQQLADLAQFQEYFSWQQLALDQPLALAFAHYRWETAAHYQLEHLTSHTDLFRCKLSLIEQATSWQLTLDYDATSMRSEVAEALAESLITMLVWLGQQSNPTFGQLPIIGSNTQTLLTKQVNATDRPFAATPIHDLIDQQALHNPQAIAVQFGAEQLSYAELAQQANQLAQQLIQHGIQPEQRVGLYLERSPLMVVALLACLKAGAAYVPLEPEYPAERIQYILADAAIQLVLSQTSLMPSLPCSVAQLAVDQLQFDQASAAPRLNYQPAQLAYLLYTSGSTGQPKGVMVSHAGLSNYVQWAITAYDLAAGTGSLVHSPLAFDLTVTSLLVPLCAGQTVRLLPSNAGVETLAQALRASTDLSLLKLTPAHLAVLNQLITSADLAQRSRALVIGGEALDATTLAPWRTHAPETRLFNEYGPTETVVGCSIYQTQTTDSAAGAVSIGLPIANMRLYVLDERLQPVPFGVVGELYIGGVGVARGYNQRPDLTAAQFVPDNLSGIAGARLYRTGDLACWAWDGTLEYLGRRDTQIKLRGYRIELGEIEAVLQRLPMVASALVLLRGTGDDQRLVAYLQATPDADSTQLSEQVVLKYAQQFLPQYMLPSNVVLVEQWPLTANGKIDRAALPEPTAINNYVAPTTPEEEILAAIWEQVLEHPMIGIDDNFFALGGNSIRSIQVVAQAKQRGLNLSVEMLFNQPTIRSLVQTMVCSTENQIIEYTPFSLISPADHALLPNTIVDAFPIAKLQGGMIFHNQFNPEQALYHDIFSYRMRVVLDLALLQLIVDDLVVRHPALRTSFDLTSASEPLQVVHAQGANLLNIIDLRNQPVEQHDQLIEAWIAAEKQRGFEPSSLPLLRFQVHVRADDELQFSLSFHHAVIDGWSDAIMLTELFSDYARRLQGQTSSLVAPQIGYHEFVRLEQAAIQNPATQQFWADHLAQASPMRLPRWPNVPRSNTSQSQPVAISAELSQALKALARQLAVPIKDVLLAAHLRVISILTGQFDVVTSMVSSGRPETLDGERVLGLFINSIPLRMQLNQPTWRELIMQTFAAERASLEHRRYPTAELQRHNGGLAWSESLFYFTHYHIFQALQNISELELLDVLPYEVSSFPLVANFRIDPFTNDINLSLTCDGRILTNAQIEAIAGYYQVCLTAMVADPAADYRAMPLLSDTEQHLLLGFNRTEVAQSSPDLVGWLAEVAQQQPTAQAIQAYDGALSYAELEQRATALAGYLQTQGIGAETRVGISLEHSTSLIVAILAVLKTGAAYVPLDPNYPRERLELMASDAELKLLICQQPDIWQNLPANSACLGLADLDSAQAPFVPVTIHPAQAAYLIYTSGSTGRPKGVVVSHANLHSSTFARTLAYREPLTSFLLLSSYAFDSSIAGIFWTLSQAGCLVLPDQAQRHDVLALASMVEHHQISHTLAIPSLYAVLLEQAELSQLASLRVVVVAGEACTTSLVNRHYQQLSTCALYNEYGPTEATVWASVAKLVPQQPISIGGPIATIQAYVVDPSLQPVPIGVAGELLIAGAGISRGYWQQPALTAERFMPDPWAEQPGQRLYRTGDLARWLPDGQLEFLGRIDQQVKIRGFRIELEEIAQLLRQHPALREAVVTAQPDQHGQLRLVAYIEPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWA7</accession>
    <name>A9AWA7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_2117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2117"/>
    <dbReference type="EnsemblBacteria" id="ABX04757">
        <property type="protein sequence ID" value="ABX04757"/>
        <property type="gene ID" value="Haur_2117"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2117"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_3_3_0"/>
    <dbReference type="OMA" id="IGFWGIS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2145-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="326" mass="35066" checksum="07282B29456DB0C2" modified="2008-01-15" version="1">MTQRLKLSVMRHGPLLTTITIFLMAYIIGAQLYPAMQRPQAFFNLFINNGFLLIIGIGMTFVILTGGIDLSVGGVLALTTAASAALLKIGFSAAFVIPLMLVMGTAIGLGLGSIIHFFKVQPFIVTLMGLFFARGLAYIISLTSVTITDPFYKYLALTPIYMPFFEKAYIYIPTLVGPLLLLVAIYLAYFTRFGRIMYALGNNEQSAGLMGFPVGRTKIMVYGFNGFCSALAGIVFSISLLAGYGQFATGVELDVIAAVVMGGTLLTGGVGSVIGTLFGILIEGTIISILQYNGTLSSWWTRICVGALTLIFIGIQSGFARRKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWP1</accession>
    <name>A9AWP1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0644"/>
    <dbReference type="EnsemblBacteria" id="ABX03292">
        <property type="protein sequence ID" value="ABX03292"/>
        <property type="gene ID" value="Haur_0644"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0644"/>
    <dbReference type="eggNOG" id="COG5459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982248_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-655-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="118"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="314" mass="34248" checksum="7C2230F9DE8D46CA" modified="2008-01-15" version="1">MSLEQLWEAYREHGYRADQPVGTDPLDLFYAALLAFGHQDVARAADFASRAAAGAPDERVFTEAAAYLGRVASQGKHNVYVSGEAFAAFIGGGGNIPLYAATSAALHAAYGEYERLDVLDIGAGNGHALIPALTPNIDRLGVVEPSAALLAELRERLGASGRPIEAFAVTAQEFARQESSSWTIIQATYSLHSIPPEERPELLRRLRDLGQRLLIVEFDVPEFASMYDPARVRDILGRYQRGLAEYADDGGLVAQGFLMPVLMGYFDQTAARTTYEQPIVEWAELVRAAGFAAVEVRPLYDYWWATACLVSGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWR8</accession>
    <name>A9AWR8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0671"/>
    <dbReference type="EnsemblBacteria" id="ABX03319">
        <property type="protein sequence ID" value="ABX03319"/>
        <property type="gene ID" value="Haur_0671"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0671"/>
    <dbReference type="HOGENOM" id="CLU_844048_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-682-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="329" mass="37790" checksum="A0A4261558095106" modified="2008-01-15" version="1">MDTSGNTLELCIDIQQKVDQSVTSMYQDWLAEVKNRSIFFKLYAIIYTIVSLGIIFSLSRNMNWQEINYPIIFTLIILSILAIPFYNLIIYLKKRFNLGSISILILIKVYFICSLFSIYIILHKYGEFNIITNLANSILYSLFFTFFAWIMFGHIVNRTFFVIFLELPYSESQWIPSFEAIQIQLVQTLKDTFDKQPLSKLTNALELLHQRRESRIHHTTILSFAVAVLALLGIVISMNPSIFTQIDKFLLLFSITKQPTSGMSMTMGIVMFIGLVLVGGFISARIYYGAFLSSSTQIVLRAYLQDRQIEEAKKDAAFLERSLTVSTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWU4</accession>
    <name>A9AWU4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated RAMP protein, Cmr4 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0697"/>
    <dbReference type="EnsemblBacteria" id="ABX03345">
        <property type="protein sequence ID" value="ABX03345"/>
        <property type="gene ID" value="Haur_0697"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0697"/>
    <dbReference type="eggNOG" id="COG1336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047795_0_0_0"/>
    <dbReference type="OMA" id="IQMSLWR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-709-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013410">
        <property type="entry name" value="CRISPR-assoc_RAMP_Cmr4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36700">
        <property type="entry name" value="PTHR36700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02580">
        <property type="entry name" value="cas_RAMP_Cmr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="32422" checksum="6F41D407495DC1B4" modified="2008-01-15" version="1">MTTKLVFVHALSPLHAGTGQGAGVIDLPIAREKATNLPYLPGSSLKGPLRDGYTGARKDEIFGTASDNATGNAGFVQFSDLRLLCMPVRSLYGTFAWVTSPYILNRLAREIKNLFTENTPPSWIENPDVDQCFVVAGSALKSNLPKSAKRKDIYLEDLDFESQADQAELVTQWADWLKKRIFGDSPEWQTMFVERFCIVNDDVFSFLLNTATEITARIRLNDETKTVADGQLWYEEALPAESILAGLMLIAPPASKTDLIQSITTELPRLWQKPIQLGGKATVGRGICRVIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AWV0</accession>
    <name>A9AWV0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0703"/>
    <dbReference type="EnsemblBacteria" id="ABX03351">
        <property type="protein sequence ID" value="ABX03351"/>
        <property type="gene ID" value="Haur_0703"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0703"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011540_4_0_0"/>
    <dbReference type="OMA" id="MFHMEHC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-715-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3656" evidence="1">
        <location>
            <begin position="401"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="841" mass="92038" checksum="E7B71CE5B1249B78" modified="2008-01-15" version="1">MSEQRRFSKPEVMSPAGYWPQLHAAIEAGADAVYFGLKHFTARAKVGFTLSELPDVMRTLHQRGVRGFVTFNTLVFEHELREATRSLAAIAEAGADAVIVQDIGIAQLARQIAPEMEVHGSTQMSITSAEGVELARRFGANRVVLARELSLAEIAAIRQATDCELEMFVHGALCVSYSGQCFSSEAWGGRSANRGQCAQACRLPYQLLVDGKHKPLADARYLLSPGDLYAVPLMHDIIKLGISSLKIEGRYKDADYVALTTSAYRKAVDEAWAGLPLSITPAEELQLEQVYSRGLGTFFIGGTNHQTVVNGRAPRHRGVLIGTVSDIYGERIVLKPHENHAIAPLKAGDGVVFDAANWRSPEEREEGGRIYGIEALPTGEIELRFGPQAIKPNRIRIGDLIWRSHDPELDRAAKPFLEAAAPVAKQPLQVHVVAHEGQPLQLTWTVSNYPQFSVTVQSPEPLPRSQNRALTNEFLFDQASRLGNTAYSLAEMNVDSSGQPFVPSSLLNNLRRQAIEQLSALQAATPTRQIQAPLEVLAQAQQTVQATPSLSNTPQLHILVRTPEQLQAAIAAKPDSITLDYLELYGLKPAVELVQAHGITVRVASPRVLKPSEQRIIHFLLKLGCEIVVRSTGLLEALRQEQHPALIGDFSLNAANSITANTLLELGLERITPTHDLNAAQVAALAEQLGSAAVEVIAYQHLPVFHTEHCVFCRFLSNGTSFKDCGHPCEKHRVELRDLNGRAHPVMADVGCRNTVFGAEAQTAVEHLDAWRAAGIVHYRLEFVHETAEQVAAIIAAFDRTLLGQQPSSVLAEQLRKAAPQGITQGSLFIPNDYLRVPLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A9AX20</accession>
    <name>A9AX20_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2188"/>
    <dbReference type="EnsemblBacteria" id="ABX04828">
        <property type="protein sequence ID" value="ABX04828"/>
        <property type="gene ID" value="Haur_2188"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2188"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_24_1_0"/>
    <dbReference type="OMA" id="CTNIITH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2216-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="17"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="142" mass="16402" checksum="C693130BA4885DD7" modified="2008-01-15" version="1">MVDIVIPARIDLLVEIASTVRRFLQTLPIIEQHPQLIYNIELAVHEICTNIITHAYEFNNAGSIAINVRFYSLTNQLEINIYDWGKPFYADQRRLPDLEHGQEGGYGLFIVEQVLDSLCYRRTATGNHWQLIKQLGATYEHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXI0</accession>
    <name>A9AXI0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0746"/>
    <dbReference type="EnsemblBacteria" id="ABX03394">
        <property type="protein sequence ID" value="ABX03394"/>
        <property type="gene ID" value="Haur_0746"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0746"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_0"/>
    <dbReference type="OMA" id="MFEVNVY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-758-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="156"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="249" mass="26379" checksum="B83667A406FB3EA0" modified="2008-01-15" version="1">MRGMQDHVAIVTGASRGIGRAIALELASWGVKVVVNYQSSAAKAEAVVAEIQAAGGVAMAIQADVTDQQAVETMVTQTLAEWGTIQILINNAGITRDNLFQRLKDEEWDDVIKADLTSAFLCTQAVLPAMRANSYGRIVSIASLAGLAGNVGQTNYAAAKMGLVGFSKAVAREVTSDGIVVNVVAPGYIDTDFIDHIPQWLRTWALDVIPLKRFGKVEEVAPAVAFLASPAASYIIGHVLTIDGGWVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXJ6</accession>
    <name>A9AXJ6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0762"/>
    <dbReference type="EnsemblBacteria" id="ABX03410">
        <property type="protein sequence ID" value="ABX03410"/>
        <property type="gene ID" value="Haur_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0762"/>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022138_3_2_0"/>
    <dbReference type="OMA" id="FHNTRGT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-774-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016833">
        <property type="term" value="F:oxo-acid-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="PTHR42738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="327" mass="34972" checksum="CD93DEEC4A8DFF9D" modified="2008-01-15" version="1">MIPLTNLPSTVSIREVGPRDGLQNEDRILTTEQKILLINALNNSGLRQIEVGSFVNPRYVPQMADTAEVFARIERRPDVIYSAIAPNLRGAQRAIEARADSVQVFLSASESHNQSNVRMSINESLAAAADIALALKEASIEFEAVLSVVFGCPFENDVPIERVVTMTERLLALGASQITLGDTTGMAHPRLVQAVVRALRERFPQAPLRLHPHSARGAGLANVLAALEVGIDRIDASIGGIGGCPFAPGAPGNICTEDTVHMLHEMGINTGLDIPKLVSCAKLIESLLGHEVPGQVIKGGICGHIPGGTMRPWNETEILGQQASRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXK5</accession>
    <name>A9AXK5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03419">
        <property type="protein sequence ID" value="ABX03419"/>
        <property type="gene ID" value="Haur_0771"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0771"/>
    <dbReference type="HOGENOM" id="CLU_2752297_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-783-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029502">
        <property type="entry name" value="Ribosomal_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14407">
        <property type="entry name" value="Frankia_peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="70" mass="7799" checksum="7255D15A266D9674" modified="2008-01-15" version="1">MSSTYSDEFQRLIDQATSDEAFRQELLDSSNIAETLKNHGFNLTDDELQQVEASASNFQGLGISARGTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A9AXV0</accession>
    <name>A9AXV0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">kdpB</name>
        <name evidence="14" type="ordered locus">Haur_2276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="12"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2276"/>
    <dbReference type="EnsemblBacteria" id="ABX04916">
        <property type="protein sequence ID" value="ABX04916"/>
        <property type="gene ID" value="Haur_2276"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2276"/>
    <dbReference type="eggNOG" id="COG2216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025728_2_0_0"/>
    <dbReference type="OMA" id="ILWLWFT"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
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            <begin position="588"/>
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            <begin position="631"/>
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        <location>
            <begin position="368"/>
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            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="359"/>
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        <ligand>
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</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY14</accession>
    <name>A9AY14_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <reference evidence="3" key="1">
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            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="69" mass="7544" checksum="97AAA8674924B5ED" modified="2008-01-15" version="1">MTEQPPKRDDDQGFEGQAGYDSGFQDGKYTNPEVAESGGVEDRAGSYEDGLRIERDDALDQTLDDQGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY18</accession>
    <name>A9AY18_HERA2</name>
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        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding LysM</fullName>
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        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
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                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
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                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ABX06900"/>
        <property type="gene ID" value="Haur_4268"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4268"/>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1914173_0_0_0"/>
    <dbReference type="OMA" id="GLYIVQP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4315-MON"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="62"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="132" mass="13974" checksum="4BC3C8209CAA332C" modified="2008-01-15" version="1">MKRRDQLAIGLICAALVGCGTPVASRPTPKPIVNLTAAPTIDLDATREAYKNELQPTAQPLGLYIVRDGDTLESIALAFNTSVEEISATNKLEDINVIAIGQPLIIPSLISGTSNLTITLPLNQSKDLTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AY22</accession>
    <name>A9AY22_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4272"/>
    <dbReference type="EnsemblBacteria" id="ABX06904">
        <property type="protein sequence ID" value="ABX06904"/>
        <property type="gene ID" value="Haur_4272"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4272"/>
    <dbReference type="eggNOG" id="COG3463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_470804_0_0_0"/>
    <dbReference type="OMA" id="IFNQVFW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4324-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="478" mass="53521" checksum="FA596B9A1EF49493" modified="2008-01-15" version="1">MQRFFATIDTYAKALLTTMIVGYIGVFATLSCLKLAWFRQGFDMAGNEQTIWNTLHGRPFQISVFAMMRYDFDDGPVLLQLPLALLYGIYQSPYTLLVLQTIALGIAAWPLYAIVRDLLPKPWHALVIAAIYLLHPTTQHINMYEFQLRSFMIPFALAALLYLRRERLGLYCLFLFLMMCTKTEAGFTLIAFGLYAAWQRKPWKFIAFPLVLGPAWVAVALGVIVPAFSEGNFIADIYSYGRLGKTVGDVITTMLTNPALAFSVMTEPPKLKYLWQLFGLGGFLALLSPTLLLALPVLALNLISPNAVQFSLNYQYGSLVYPFLLVASVEGLLNLTRWTVRNSQWRERAVHGAVLVLLLIGIIGNLTLNNVVKTALSNRENPTRVADARAILAQVPADAAVAASTFLAPHLAQRQEIYFFPGNKSYPAEYIERAEYLVFDRRPPGNSAETRAAIERYLNDPDWVIVAEAGDFALLKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD4</accession>
    <name>A9AYD4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ASPIC/UnbV domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0868"/>
    <dbReference type="EnsemblBacteria" id="ABX03516">
        <property type="protein sequence ID" value="ABX03516"/>
        <property type="gene ID" value="Haur_0868"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0868"/>
    <dbReference type="eggNOG" id="COG4658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432058_0_0_0"/>
    <dbReference type="OMA" id="VYIANDF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-882-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UnbV_ASPIC" evidence="2">
        <location>
            <begin position="561"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="638" mass="69267" checksum="FCAC57F37FBD0096" modified="2008-01-15" version="1">MKQTLLKYQTQLLAVAVLVGTFIVAQPPTLSQAEQADLSQSFGFAQQPLAALAGHTQRFIRPVNPSLAHIDAWISSVGAAIALNDLDNDGLSNDICYVDTRIDQVVVQPAQTSNARYPAFALDPNSLKYDASTMAPMGCLPSDINEDGMLDLIVYYWGRTPIIFVQQYQGANVDLSSQSYVAQELVTTGERWFTNTGLVSDFDGDGHQDLLFANYFPDGAAILDAKSSRKQTMQASMSRAFNGGDKHFFLWQQTSTEQAPFVAVPDVLSGELNHGWTLALGTYDFNNDLLPELYIGNDFGPDRFLINRSTPGTIKLELAEGSGGFTIPTSKVIGHDSFKGMGVDFSDINSDQHPDIFVSNITTPFGLHESNFAYVSDPSAKLDQSELPNYTDQSEQLGFGRSGWAWDIKLADFNNDQRDEILQATGFVKGTINRWPELQELATGNDQLLADPASWPRFSAGDDIAGHQINPFFSQAADGRYYDLAKTLGFAPTVSRGIAVGDVDGDGKLDFASANQWEDSIFYHNTSQSSNQALGLRLRIASDGKASNITGFQPTSAAIPAIGAHVTVKLPDGRTVSSQVDGGNGHSGKRSYDLHFGLGALDPQTQLEVTVRWRGRDGSVQTSVVQLTPGNHTLILGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYD5</accession>
    <name>A9AYD5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0869"/>
    <dbReference type="EnsemblBacteria" id="ABX03517">
        <property type="protein sequence ID" value="ABX03517"/>
        <property type="gene ID" value="Haur_0869"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0869"/>
    <dbReference type="eggNOG" id="ENOG502Z8MJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074815_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-883-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012964">
        <property type="entry name" value="DUF1702"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08012">
        <property type="entry name" value="DUF1702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="317" mass="35565" checksum="72A5E93C6EB45FA1" modified="2008-01-15" version="1">MLLNRVLTYPLRLSPLEATFARRGFPIGDRQNQARLETIGKTFLHGYHAALDNQGLGQLKRQLEQIDPQLQGFGFEGTGMGLAILDQITPWKGQRVQAFLANEGQHQRYVIHVGVGWAVARMRWTLPKVVQALDPILRWLVLDGYGFHQGYFAWHESFIQQHYPQKFDAKQLAIFDQGLGRSLWFVTSSNPRMIANVISRFAQERQINLWAGVGLACTYAGSNNPEALHAIAELGATYSTAITQGVSFAAKTRLHAGYVPEHSELACQILCQQSVAEAAAITDQQLLRVNQNGSIDSYHHWQELIRACYLKKEAIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYN9</accession>
    <name>A9AYN9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2377"/>
    <dbReference type="EnsemblBacteria" id="ABX05017">
        <property type="protein sequence ID" value="ABX05017"/>
        <property type="gene ID" value="Haur_2377"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2377"/>
    <dbReference type="eggNOG" id="ENOG502ZY2M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170234_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2405-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="114" mass="13082" checksum="4646199071D3CB64" modified="2008-01-15" version="1">MSDGFFTLPCRVVLPAEQRDRLERLCRARSMEVSDLVSELVVQYLDEVPDSALAEPIPEPYAPSLSEQLRQNERELRRLLMRQNQLGASAPGWLDNYVADVEREIAVLRRKLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR2</accession>
    <name>A9AYR2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05040">
        <property type="protein sequence ID" value="ABX05040"/>
        <property type="gene ID" value="Haur_2400"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2400"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043258_0_0_0"/>
    <dbReference type="OMA" id="ATMVAIC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2428-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="58"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="444" mass="49046" checksum="A5BF3BCE332B480F" modified="2008-01-15" version="1">MLKRQLTRLGYLLLACLPLLLAASIGSYYSMQVAMSIRSDKPNIQSQPIVYDAQKPTAVILLGNTVSEITDVLAPYALLAKTGLYNVYTVAETSSVRSLSGGLDLLPDYSFAGLATLLKQPPALVIVPAITEIQASQNQPVLAWLRQQSQAASTVMSWCTGAEVLAESGLLDGLPATAHWADLSSLQKRYPKVKWQNNQRYVDINQQIITTAGLTSGIDATLYFLQKMHGADVSQQLADMINYSDQSYLEHATMQPFSITPSDSVYLLNAAFYWPKQTLGIWLSQGVDELALAAFFDVYTGSWVYDFRTIGAEPNIRSAHGLQLIPRYQAATHIDRLVGFGPNQQAQTWAEQQQMTYHELDLAQQGNMFEQALVRFAIDQDQASAQFAAKRMEYRQPLTLHGASWPWRTLIGIGVWLGVGIGACYGLRRISNKRKSAATNENLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYR9</accession>
    <name>A9AYR9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2407"/>
    <dbReference type="EnsemblBacteria" id="ABX05047">
        <property type="protein sequence ID" value="ABX05047"/>
        <property type="gene ID" value="Haur_2407"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2407"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_0"/>
    <dbReference type="OMA" id="CEQYISV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2435-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="411"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="498" mass="55113" checksum="0C6E70BCDDD4FCF3" modified="2008-01-15" version="1">MNIAQHIEKARLHSPNKLALIFEHTHYSYQELDQQANQVANGLAQLGIRVGERVALFLPNIPEFMVGYLGIIKLGAIAVSLNVQLQRDEIKFIINDSQATAMITTPELAQRVPTAECPSLKHVLVTDSADASTSLARLIESAPKEYQARAMQPHDPAAIVYSSGTTGFPKGVTLSHHNIISNMQAKNRYCDMRSSDSLLLCVPLFHCFGQNAIFNSALNAGATIVLHRSFNLDLVLRSIQTDQVTMFFGVPTIYLLLLNKTEPEQFHAVRYFFSGAAILPVEIAQRWYAKYKLPIHEGYGLTETSPFAAYNHISNYKLGSVGVPIEQVEIKIVDIETDVEVLPDEVGEIIIRGPNVMLGYWNNPTATAQAIRNGWFHTGDLGKKDQAGYLFIVDRLKDMINVAGIKVYPAEVENVIYQLPEVAEVAVYGVADAITGERVEAQIVFKPKQQLPIQAIIAFCRQHMASFKVPTAIKVVDSIPKNPTGKVLKRLLRNEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYU8</accession>
    <name>A9AYU8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX06988">
        <property type="protein sequence ID" value="ABX06988"/>
        <property type="gene ID" value="Haur_4356"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4356"/>
    <dbReference type="HOGENOM" id="CLU_1765532_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4409-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX06988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="147" mass="16041" checksum="C4BC56673F0C2BD9" modified="2008-01-15" version="1">MPVAKRLRGLWIDAVLLGLAISLFIPAIGAAQVAGFSLELTIALLLLLIGGLIAKAIRHGMHLYSPPAEREAKLNGQLQQALVVSATPTGWLRGTYGRRIFEFELELRLEQTALKIYPFLELLKAPDAGDMVQVKIHPDNPNVIVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9AYW7</accession>
    <name>A9AYW7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein serine phosphatase with GAF(S) sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4375"/>
    <dbReference type="EnsemblBacteria" id="ABX07007">
        <property type="protein sequence ID" value="ABX07007"/>
        <property type="gene ID" value="Haur_4375"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4375"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_527626_0_0_0"/>
    <dbReference type="OMA" id="MDASARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4429-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="132"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="297"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX07007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="516" mass="56633" checksum="3A3FA02F45308927" modified="2008-01-15" version="1">MNRARRHRDVISISLLLSVITIVMYLGEGRWAAAPALRYLYLIPIAQAAMGFGLMGSMAVAILADLLFAPLVATALAKYGMFGAPTVEIIVTLVLMPVLAYFAGSGWGRLSRQRELYQFLSRMGDLFGRSLPRDQLLAEILQEGGLLIDAQGGEIILLEQGQARIAASWGIEAQATAAYQTSLAAYILKRNEPWSATSLENNSDFQRVGFGQRIDAALAVPLRLEGKPIGLLAFYNRPGGFSKQEQATVEAMGSKVEVVLENFRQVEERSERARLQREFDLAAEVQQRFLPQQLPAISGYEIAGFTQPAREVGGDFFNVLSLPDGRWYIAVGDVSGKGVVGAFFMAIAMSVIDLHLQEGQSTTQLSLANRLNPLFYRRMAQQKINTGLAYALLDAKTGHMQLGNAGLIAPLHVRKNGECDYLDLTGFPLGAVAQAEYSESVLELQAGESLIFISDGVVEAANHDRELFGLNRLRNLISMLSQRPASQLVSEIMNAANRWSDGQYQDDMTVVVLRRI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ03</accession>
    <name>TAL_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable transaldolase</fullName>
            <ecNumber evidence="1">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tal</name>
        <name type="ordered locus">Haur_4411</name>
    </gene>
    <organism>
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transaldolase family. Type 3B subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A9AZ03"/>
    <dbReference type="SMR" id="A9AZ03"/>
    <dbReference type="STRING" id="316274.Haur_4411"/>
    <dbReference type="EnsemblBacteria" id="ABX07043">
        <property type="protein sequence ID" value="ABX07043"/>
        <property type="gene ID" value="Haur_4411"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4411"/>
    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079764_0_0_0"/>
    <dbReference type="OMA" id="VRHPMHV"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00494">
        <property type="entry name" value="Transaldolase_3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022999">
        <property type="entry name" value="Transaldolase_3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004731">
        <property type="entry name" value="Transaldolase_3B/F6P_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00875">
        <property type="entry name" value="fsa_talC_mipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0570">Pentose shunt</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0704">Schiff base</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000126320" description="Probable transaldolase">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00494"/>
        </source>
    </evidence>
    <sequence length="221" mass="23819" checksum="016FECAE19C284F8" modified="2008-01-15" version="1">MKIFLDTADVEEIRQGVAMGVVDGVTTNPSLAAKAGRNFRDVVLEIVEICPGPVSAETVALQADEIVREGRILAKWAPNIVVKVPLMAEGLKAVKQLTSEGIKTNVTLIFSASQALLAAKAGATFVSPFLGRLDDIGQDGMILIRDIVQIFKNYNIQTEVLAASIRHPVHVLQSALAGSHVATMPFKVLQQLVKHPLTDKGIETFLVDWQQVPDAATVFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ30</accession>
    <name>A9AZ30_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4438"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07070">
        <property type="protein sequence ID" value="ABX07070"/>
        <property type="gene ID" value="Haur_4438"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4438"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_6_0"/>
    <dbReference type="OMA" id="VKFLDYV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4493-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="202"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="381" mass="41640" checksum="5EF48604CD6EC788" modified="2008-01-15" version="1">MHIAIDYNAAVRQGGGIGRFVREITQVAAQAAPQHRFSLWYAARGLDPKSAQMQALHELQRRLPNIKPRPIPINERLLTILWQRLRMPLPVETIVGAVDVVHGTDFVLPPTKAKTLLSIHDFAYIIHPETAPPELRRYLGGVVPRNVRRADHIHVNSRATKADMERLLGTAPSKSTIVYSGSGSDFYPRPAAEIAEMRQRLGLPERYLLNVGTVQPRKNVERLIEAFGQLPAELRSQPLVIGGKRGWLAEPIYAAVQRHGLEQAVIFLDFVSDSDLPKLYSGATAMVYPSLYEGFGVPIVEAQACGTPVITSTISSLPEIAGNAALLVDPHDTAALTAALQKILTEPDVCQSLAEAGPRQAAKFTWEGTGLGVLGLYELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ75</accession>
    <name>A9AZ75_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_0973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0973"/>
    <dbReference type="EnsemblBacteria" id="ABX03621">
        <property type="protein sequence ID" value="ABX03621"/>
        <property type="gene ID" value="Haur_0973"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0973"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_0"/>
    <dbReference type="OMA" id="NCIFLLN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-987-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX03621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="412" mass="45547" checksum="D46EEAC55041FBE1" modified="2008-01-15" version="1">MTQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYAEAVQVLKDSRFTVDATILNPEAGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVAKAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAYPLPINVISEMLGVPTHERDQMREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESELLATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSPAPRFALEDVEIAGQPIRRGDLVLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHFCLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNVNLRGLKALPVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZ83</accession>
    <name>A9AZ83_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0981"/>
    <dbReference type="EnsemblBacteria" id="ABX03629">
        <property type="protein sequence ID" value="ABX03629"/>
        <property type="gene ID" value="Haur_0981"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0981"/>
    <dbReference type="HOGENOM" id="CLU_2342907_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-997-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="97" mass="10544" checksum="DF8E934136751A3C" modified="2008-01-15" version="1">MAGLIGIAALVNLLWQPFSWALLLQTIVHSCVAGLIATYGLAVRSTPNHHHRYRRSLGDMLGLRFSWMPWHVARLAYGLVLVGCVAGLGVVLLVLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZG5</accession>
    <name>A9AZG5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2471"/>
    <dbReference type="EnsemblBacteria" id="ABX05109">
        <property type="protein sequence ID" value="ABX05109"/>
        <property type="gene ID" value="Haur_2471"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2471"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_3_0_0"/>
    <dbReference type="OMA" id="GVVWDFN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2499-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002732275" evidence="1">
        <location>
            <begin position="34"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="390" mass="41644" checksum="F9596D6E8B4BF852" modified="2008-01-15" version="1">MAQSKLGAFRLRAAKLAALFLVVSLMISACGSAASESTTAPTAGSGGTSSTMDALIAAAKAEGELTVIALPHNWLNYGEMIENFSKKYGIKINELNPDAGSGDEIEAIKANKDNKGPQAPDVIDVGFAFGPSAKQENLLQPYKVSTWDTIPNELKDPEGYWFGDYYGVLAFAVNKDVVKNVPQDWADLLKPEYKGQVALAGDPRVSNLAIQSVYAAALANGGSLDNVQPGLDFFSKLNQAGNFVPVIAKQGTLAQGETPIMITWDYLAISARDELGGNPEIEVVVPKSGVLGGVYVQAISAYAPHPNAAKLWMEYLYSDEGQLTWLKGGGHPVRYNDLVARNVIPAEIAEKLPPAELYANAVFPTLAQLEAAKKVIVDGWDTTVNVDVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZN9</accession>
    <name>A9AZN9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_4461</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4461"/>
    <dbReference type="CAZy" id="GH57">
        <property type="family name" value="Glycoside Hydrolase Family 57"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07093">
        <property type="protein sequence ID" value="ABX07093"/>
        <property type="gene ID" value="Haur_4461"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4461"/>
    <dbReference type="eggNOG" id="COG1543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008192_1_0_0"/>
    <dbReference type="OMA" id="CAYYEGL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4516-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037090">
        <property type="entry name" value="57_glycoside_trans_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015293">
        <property type="entry name" value="BE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09210">
        <property type="entry name" value="DUF1957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="4">
        <location>
            <begin position="8"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1957" evidence="5">
        <location>
            <begin position="540"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="649" mass="72794" checksum="13B04A0EE95D82D5" modified="2008-01-15" version="1">MPKQGAFTFVLHSHLPYCRKAGRWPHGEEWIHEAASETYIPLLNALNDLINDGVTPRLTIGITPILTEQLADPTILHNFEEYLDEKITAAQADMDRLADVQAVWDAAQVAEPETEPTPLLSSEELESLISKSDALLSSTAGDAPAPLHAGLLSATAAASTEAEADDEAESEETEEAAVEEPAPIEQPDPHKAYLAMWYRDWYSMIKRSFIERYNRDIVGAFRQLQDAGYIEIITCGATHGYLPLVSRDSTIYAQIAVAVQSYERHYGRKPKAIWLPECAYRPAYYPENPSETERKPGIEEFLEAQGIECFFVETTTIEGGAPMDKAEGKILGPYGDTLRRYVVPVSREIPPTGNSTLQPYLVGLSDKVAAIGRHHKTGLQVWSAEWGYPGEANYREFHRKDSESGMQYWRITGPKVDLGYKDYYHPDWVNDKVNAHAEHFTGLVQQVISEYRGQTGRYGLISSNYDTELFGHWWFEGVDWMREVLRRLATNPDIDLTTASEYIASNPPRESLNLPESSWGSNGTHQTWLNPETEWMWPIIHAAEKRMEGLVASYPQADGALAEALAQTARELLLLQSSDWPFLVTTGQAQDYATKRFNEHVDRYNQLADAIEANDVGLMAELTASFNELDNPFPTIDYHVFAAREGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9AZV9</accession>
    <name>A9AZV9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_4532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4532"/>
    <dbReference type="EnsemblBacteria" id="ABX07163">
        <property type="protein sequence ID" value="ABX07163"/>
        <property type="gene ID" value="Haur_4532"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4532"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388654_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4587-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX07163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="642" mass="70869" checksum="24C4092D35EF1FE9" modified="2008-01-15" version="1">MLKSGTIIQDRYTIVRPLGSGGFGAVFLATDGRLGQRNVAIKYFATAHMRPDELDSLAHLFQQEAHTLASLSHPNLAPVLDYFAVDDGWMLVMGYVPGESLSALQKRLNGPFGEQQVIDWAIELCHVLEYLHNQRPPLIFRDLKPANIMRTPEGKVILIDFGIVRRFKEGQHQDTIQIGTPGYAPPEQYGGQTEPRSDLYSLGSTMYVLLTNERVTSGLRLPPVSQSVEWVSPALDDLITQLTSLHIDQRPASAAAVRAELERIRDTPIVPIADPFAIVPQAAPYRNAEAPTRVNPQVQQQQSYGHASVTPQPIQANPQPEFSPRKAQIWPWLLLFVLLFGGGGACWWYLNRSSTPDQPLVVPTLPSALPDSAEGDLIISSREGNSGAYNLLSLDIPTGAVSEVVPHHDDNAIASRRRSDGRVAYSHGVDGLEQIFTISANGSDEQQLTSAPGESRAPRWSPDGSKIAFESDRDHSNNNSFDIYIMDADGSNVQRVTAEGGWQGGPAWSPDGTKLAFHSQTSGLYEIVVLDLTTNKQYLLASVDDSAFWADWSPDGQTIAFMTGDNDSRTKIYTVPTSGGEPRELTNLGTGKNRWPRWSPDGRYLAFESYRNDHWGIYLQHLATGKVEALSDGTRHDRWPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9B004</accession>
    <name>A9B004_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ornithine carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_1063</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1063"/>
    <dbReference type="EnsemblBacteria" id="ABX03711">
        <property type="protein sequence ID" value="ABX03711"/>
        <property type="gene ID" value="Haur_1063"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1063"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_0_0"/>
    <dbReference type="OMA" id="FPMFVWG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1080-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="86"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX03711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="293" mass="32483" checksum="B229D9CABD4C3036" modified="2008-01-15" version="1">MMAKILADKRIETKHGRSRPVAKRHMPWGTWALTLNAIFVYTFLYVPIIVLVLFSFNAAKVGSQWQGFTLQWYNELFADARLGDALWTSLKIAGSSTLIATTIGTLAALALEKRGWWGRKTFDTALYLPVIIPDVVMAVSLLGFFTLAFRQFQALIGLNLAMGLWTVIISHVAFNISFVTVVVGTSLANFDRRLEEAAADLGATPWQTFWRIKFPLIGPGVLGGALLSFTLSLDDFVVTFFTRGPGVNTLTTEVYGRIKKSISPEINAISSLMLLASTTLVVTSLWMQRRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B040</accession>
    <name>A9B040_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1099"/>
    <dbReference type="EnsemblBacteria" id="ABX03747">
        <property type="protein sequence ID" value="ABX03747"/>
        <property type="gene ID" value="Haur_1099"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1099"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773641_0_0_0"/>
    <dbReference type="OMA" id="EAFEEEW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1119-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="269"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="359" mass="41048" checksum="AD4AAA214E4033A0" modified="2008-01-15" version="1">MTELVRAQPAFKVDFVPSLGLDLLSTMGLIGIVHDFEGLDAWLVEAAASVPPRLRHDIQLAMRMGVYPYVVVETVSDQILQPGAAGHDDFNGLIEDLKALSPQECAAMVHKIVQRTAANADVELLHTPAEIIADQEQLEELLAKMQFPVDTDELIELLQQPTEWRDLLVSTIQRFWDRIYREQYELQQARRERNAHYHRTHQYSVNFRDLFAGVTGRRLPDHIHERLGTISTVRFVPSQYIGPYLSFLFNGSLLTVFYNSSTTPAEGDEQTERTQSLYQPLAALADKTRLQIMTLLHGRELYAQEIVNLLDIHQSAVSRHLKLMETSGVLNVRRDKGAKYYSINRQRIEEISARLREFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B085</accession>
    <name>A9B085_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2556"/>
    <dbReference type="ESTHER" id="hera2-a9b085">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05194">
        <property type="protein sequence ID" value="ABX05194"/>
        <property type="gene ID" value="Haur_2556"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2556"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_2_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2584-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="82"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="32265" checksum="3D0E6DA6447C4AFC" modified="2008-01-15" version="1">MDEYTISVQGTVGQEAIRVLQRSTGAEQFIAWHGITAVNRFWLWDALWPHGEVQLVGLPGHGAVPNQPNQQWSRWTQEHLIETGIASLKKLNNGKPATIIGHSTGGLIALGIAHRAPELVKRLIVLSPVVWSELTGIVNVWQRFVGQPSLLKAIIHSSLGLGRCSHWAFSKSLVAFIKDRQGFYSNPKVVKTIRDGYEQMQQTPIAGIAGITTVLKQADIRPLIMAKPTTVPTLIVHGQHDPIVPFKQAQWLKLNIPQANLLAIPHVGHLPYAEQETYVNKEVTNWVEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0A8</accession>
    <name>A9B0A8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2579"/>
    <dbReference type="EnsemblBacteria" id="ABX05217">
        <property type="protein sequence ID" value="ABX05217"/>
        <property type="gene ID" value="Haur_2579"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2579"/>
    <dbReference type="HOGENOM" id="CLU_2316445_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2607-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="99" mass="10736" checksum="9CA95976CD162930" modified="2008-01-15" version="1">MAEVEVYLEQGPVEKIAKTLNTIGQVLKTVAKVLEVLSTTLKATAFIGLVGGYAVAQYIDQFRPTIEKMSEKLLETAGEVNKAVQAYINQDSTLSGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0E7</accession>
    <name>A9B0E7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_2618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX05256">
        <property type="protein sequence ID" value="ABX05256"/>
        <property type="gene ID" value="Haur_2618"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2618"/>
    <dbReference type="HOGENOM" id="CLU_2464813_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2646-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX05256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="88" mass="10288" checksum="E19F890E8AF11784" modified="2008-01-15" version="1">MTADMLIETQADGIKGRIWFSINRDTRREHKNQQQENEAIIPFHTSAPTKTRVINYQTLLSLQRAIYALINLNKWSIVRHLVPSRSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A9B0F0</accession>
    <name>A9B0F0_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosyl pyrophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.6.1" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2621"/>
    <dbReference type="EnsemblBacteria" id="ABX05259">
        <property type="protein sequence ID" value="ABX05259"/>
        <property type="gene ID" value="Haur_2621"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2621"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_2_0_0"/>
    <dbReference type="OMA" id="HYAYARS"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2649-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="35664" checksum="CBF965A67C168FD9" modified="2008-01-15" version="1">MSRFDEMRIFSGTGNPTLAQAISSYIGIRHGELSIHTFPNENIFVKIEESVREQDVFVVQSLGAPLNHLIMEMLIMLDAFKRASAGRITAVIPYLAYSRTDKKDQPRVPITARLLADLIVAAGAQRVLTLDLHAGQVQGFFSVPVDEMSTMHLLTNEVKSWGLENGIIVSPGLGFAKKARNFAEAVNMPLALVEKRRINHHDGTVGHLAILGDVADHDCVIVDDEVATGHTMVRVSELLMERGARSVRACCIHPLLYGDSVERIKRSPIERFVTTDTITLPPEKRWPALVVKSVAPLLGEVIQRIHTGISVGAMFPAGPQIGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B139</accession>
    <name>A9B139_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_2679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2679"/>
    <dbReference type="EnsemblBacteria" id="ABX05317">
        <property type="protein sequence ID" value="ABX05317"/>
        <property type="gene ID" value="Haur_2679"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2679"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914568_0_0_0"/>
    <dbReference type="OMA" id="WPASFPM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2709-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="86"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="304" mass="35099" checksum="35AE69C5BD7C74CB" modified="2008-01-15" version="1">MSWPRFWLGLWLFGLGLSYSNVIDLLSVLQPWFFAPALPLLLWAIPQRRRWLSVMAIFIGLIWLWLYAERWLPQPRPDTTPALRLLSWNVAGWNLNSVDILRVIDDEQPDLIALQEVDVGLGKPLQTALASKYPYVEFRPASGAAQPADLALWSKWPFALIHPCAYWQCYRRAYRVQHPQQPLILVNVHIEHSPIRWLRFEREREEAAIGQMIADFGQTTEPVLLAGDFNTVEQQAGYAALNTVWGDSWHERGVGMGFSWPQRSWHPPIVRIDYIWHNAAIRPIQLETGAGVSDHRYLIGAFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B163</accession>
    <name>A9B163_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Squalene/phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2703"/>
    <dbReference type="EnsemblBacteria" id="ABX05341">
        <property type="protein sequence ID" value="ABX05341"/>
        <property type="gene ID" value="Haur_2703"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2703"/>
    <dbReference type="eggNOG" id="COG1562">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037269_1_3_0"/>
    <dbReference type="OMA" id="KLYCYRV"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2734-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="324" mass="37218" checksum="3D66748B13D381E0" modified="2008-01-15" version="1">MSWPSLDPQMCAGLTLPAQFIPTVAECVSHQPSNQWLNHAYAHCTELTNVHSKSFYFSTQLLPARKRDAIRVLYAFCRTSDDLVDMHPETAPERLQQWLKTLRSTPRHDDPVPLAWHHVRNHFRISSKLESELLAGVEMDLSINRYATFADLWLYCYRVASVVGLLSMQVIGYAAGAVPYAIKLGVALQLTNILRDIGEDARRNRIYLPKEDLERFGVSEQDILNGVRSPQMQQLLQFEMQRAHQLYDESWQGIGLLHPDSRFAVATAATVYRGILDQIVRNNYDVFNRRASLSLGAKLAYLPKILWRLRKLNREFPLDQWGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1N1</accession>
    <name>A9B1N1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_1268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1268"/>
    <dbReference type="EnsemblBacteria" id="ABX03916">
        <property type="protein sequence ID" value="ABX03916"/>
        <property type="gene ID" value="Haur_1268"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1268"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_707314_0_0_0"/>
    <dbReference type="OMA" id="CIILADR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1290-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="PTHR13323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="410" mass="43702" checksum="FB34EE9212A08651" modified="2008-01-15" version="1">MGYRVFVVAGDNPVLQSLSTAVTGEIELSMLQSSNEALWELQQIAPDVLIADYDLPGFSGLDLADLVPNFAPDTRVILVARSANPEVAEQAAQRGVFRFIDRNLTAVLVLDALDEALQAVPPPRPVEPEPVYEPEPEPEPQPEAPARFAPPPSVSKAPAPARMGGPPPVSKAPTPVARSTAPASVSKAPPPVSPRPTAPPQRTRTAPPPVSARPTPVSRSAPPPVSPRPATQQPNRQAPAPARPTAPAQQTPPPAQQAPPPAPTTNFDDSFGSKLRSGGSLVLTAETLAPLVAKLKDLGVQLGAQSTILTDRWGVPLVEEGHTSLPLPPFLPLLATSFSTMVDYTRQLHNDPGSGLYMHEGDIYDFYIFDVGRQFLLVMVFDKTIAAPKLGTVWLYAKRAVRELADELEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B1X3</accession>
    <name>A9B1X3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF5667 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_2777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2777"/>
    <dbReference type="EnsemblBacteria" id="ABX05415">
        <property type="protein sequence ID" value="ABX05415"/>
        <property type="gene ID" value="Haur_2777"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2777"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_540664_0_0_0"/>
    <dbReference type="OMA" id="PRIMHWQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2808-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043725">
        <property type="entry name" value="DUF5667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18915">
        <property type="entry name" value="DUF5667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5667" evidence="3">
        <location>
            <begin position="113"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="428" mass="46290" checksum="7FC1893B88CD23BE" modified="2008-01-15" version="1">MNDNLSHMIIDAWQNGASLETLCQQYPHHAEAIQQLINPLIQLQRVNPPTMPARASHAQADFMRLAQHYRAQTAPKPKPRRRLLTQRWVWATATILLLVCLSGNLVLSASASALPGDSLYGIKRWSESISLVFTPSAEQLTARIDLVNERQHEIASLVALNKPVPSELLDEVVNETQSIELALAPTHTNDPRRSKLSQVNQQLQTTIAIIPVENATDNLKHHDLIETLDQSRQRIDIANLTTIPTQPAKVLVGPTATKQPSIAPAATDLPHIANPKLPPKPHTPTQEPTEVVLPTSTSTPWPTAKPTRVPPPVIKPTATATSLPTSAPTDVPMPTSAPTDVPMPTSAPTDVPVPTEIPSIGLPTATPTIVREQPTAPVPTKDPGDIKPTEVPPTSPPTSPPPTKEPPPPSPTKEPEDTKGQPNPILQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B214</accession>
    <name>A9B214_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4733"/>
    <dbReference type="EnsemblBacteria" id="ABX07364">
        <property type="protein sequence ID" value="ABX07364"/>
        <property type="gene ID" value="Haur_4733"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4733"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1765533_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4791-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="147" mass="16762" checksum="83692FDFD0F596B1" modified="2008-01-15" version="1">MATLRHTRYQVAIMDHDCLLLIRFASATTTFWLLPGGGREPDESENDCLIREAWEELGVRIVVEGLILHQQDQPDQTYQAFKTYRCRIIEGTPQPGYETINPNDPSAGIVEVGWVDLTAPETWPALIVNNLYTFKLLQQLRQSLGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B223</accession>
    <name>A9B223_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4742"/>
    <dbReference type="EnsemblBacteria" id="ABX07373">
        <property type="protein sequence ID" value="ABX07373"/>
        <property type="gene ID" value="Haur_4742"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4742"/>
    <dbReference type="eggNOG" id="COG5530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089301_0_0_0"/>
    <dbReference type="OMA" id="VIQENLF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4800-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014470">
        <property type="entry name" value="UCP01500"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10028">
        <property type="entry name" value="DUF2270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="258" mass="29799" checksum="9109BCBAAFD6121D" modified="2008-01-15" version="1">MASYNAYMRPSRSAQQAAPPAAMVHLYRGLMDRAVTWRSRIDTPTNWAVAITGTVSSFVLGDANHHHAVVLLTIVFCMGFWFIEARRYRYYDLWATWVRILETDYYVPLLGQNTLAVDQYWHKLLLTDMNTPHFKITTLEALGRRLRHNYMAIFLFLLFIWLLKLMIHPQITNRPSLETFIYDASLGPFNGKFVILSVLGFYALLIIVALITIPRWGARTEMVSHERVLRKLALPEAMPVGKAKRRGGRRKSYGKAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B266</accession>
    <name>A9B266_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4785"/>
    <dbReference type="EnsemblBacteria" id="ABX07416">
        <property type="protein sequence ID" value="ABX07416"/>
        <property type="gene ID" value="Haur_4785"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4785"/>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4843-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="216" mass="23924" checksum="71B63E4467BB1F05" modified="2008-01-15" version="1">MRLGLLADIHGDGVGFQQALAWFESQAIEQILCAGDVVDRGPDADAIVQGLIARSIPCIKGNHEFTLLREHGRWSQSSQRERLASRGRIVTQATLAYVAALPTSLRLQVEHRSLVLAHGAPWSDVVDMLPESRSSKWQRLVREHPNDQIIVLGHTHRPMHVRCGHLTVLNPGSVYGVTIRDSHTCAIYDTTSDSLTLYDLRSQQTRICPVVEVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2G4</accession>
    <name>A9B2G4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04009">
        <property type="protein sequence ID" value="ABX04009"/>
        <property type="gene ID" value="Haur_1364"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1364"/>
    <dbReference type="HOGENOM" id="CLU_1553167_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1385-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="172" mass="19483" checksum="23B638E31CA697A2" modified="2008-01-15" version="1">MSDDNQYSDIPHAALRSYIEQKGWVRRYPNLTGGKPIGYVYFDDRYIDANILKFVEPLNLANAIHFAPKVPKQVEQFIPNNPMGSLRLNIQNTIFYFVIPKQELEDLFNKSGMSVAEVIKSHNEEKIREMGIIYSDHQGVLDSAIGKHVVIPKGGGFVDLDGSEIHLPTVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2H2</accession>
    <name>A9B2H2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1372"/>
    <dbReference type="EnsemblBacteria" id="ABX04017">
        <property type="protein sequence ID" value="ABX04017"/>
        <property type="gene ID" value="Haur_1372"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1372"/>
    <dbReference type="HOGENOM" id="CLU_1376512_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1393-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="198" mass="21160" checksum="C154C3905EB5DCE8" modified="2008-01-15" version="1">MPTDVAAVTMSNATLFYAPVGTTLPADSLAVGAAWPVGWVQYGLTSAPLVVAYSYETKAPEIQEALGAVKRKKVSEELTAETTMAQLDFAGLPSTWGGTNTVVASGVGQVGKETFKIGGAAQLPIRMWGFEAEQEDEEGNVFPVRGFIWKATAEEGGELEFSKEDWTGLPLKLSALEDLSRTKGERLFQLVRVVEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2L7</accession>
    <name>A9B2L7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_2830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2830"/>
    <dbReference type="EnsemblBacteria" id="ABX05468">
        <property type="protein sequence ID" value="ABX05468"/>
        <property type="gene ID" value="Haur_2830"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2830"/>
    <dbReference type="eggNOG" id="COG2316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090635_1_1_0"/>
    <dbReference type="OMA" id="EMLGWEL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2861-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX05468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="193" mass="21404" checksum="AD36927FC5F73D06" modified="2008-01-15" version="1">MVNSYAAAEALLAEWVQSESLRKHCLAVSTSMRHMAQRQQVDAELWATVGLIHDLDYERFPNAAQSPTAEHPSEAVRVLRELGWSEEICRAILSHADYCHVERITPMEKTLYAVDELSGFVTAVALVRPDKSVHSVEVSSVKKKMKDKAFARAVNREDIIRGAQELDVPLETLIEEVITALRGNAVALGLNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A9B2U5</accession>
    <name>A9B2U5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP oxidoreductase coenzyme F420-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3372"/>
    <dbReference type="EnsemblBacteria" id="ABX06008">
        <property type="protein sequence ID" value="ABX06008"/>
        <property type="gene ID" value="Haur_3372"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3372"/>
    <dbReference type="eggNOG" id="COG5495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055635_1_0_0"/>
    <dbReference type="OMA" id="WQVVEEE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3409-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018931">
        <property type="entry name" value="DUF2520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019665">
        <property type="entry name" value="OxRdtase/DH_put_Rossmann_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037108">
        <property type="entry name" value="TM1727-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10728">
        <property type="entry name" value="DUF2520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10727">
        <property type="entry name" value="Rossmann-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rossmann-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2520" evidence="2">
        <location>
            <begin position="137"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="271" mass="28437" checksum="7683EB4487157C09" modified="2008-01-15" version="1">MAFSARPTVGILGAGKVGTALALALQRADYSIVGVSSRSPTSAQALAQSLVCPVLVPNQLFAQAQLIFLTIPDDHLATTAQALADVLDHGTGIVVHCSGALTSAVLQPLQLRGWQVAGCHPLAPFASRTTPLPPAITWAIEAEADVYLVLAELVQAVGGTPRPIQAEHKVLYHSAAVLSANYAIMLAARAVDLLQLCGWSSQESLQALVPLLRDNVENLARVGLPQALTGPLARGDYGTVERHLQALDANAPDIASLYRACIEATQPLLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9B332</accession>
    <name>A9B332_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5668 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_4865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07495">
        <property type="protein sequence ID" value="ABX07495"/>
        <property type="gene ID" value="Haur_4865"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4865"/>
    <dbReference type="HOGENOM" id="CLU_955699_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4925-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043726">
        <property type="entry name" value="DUF5668"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18917">
        <property type="entry name" value="DUF5668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="2">
        <location>
            <begin position="13"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="291" mass="32078" checksum="C5D3B9F6BF9DE3ED" modified="2008-01-15" version="1">MTVMTEQVQRRSLFWPCLLIGLGVLGALSAINLFDASLFDLLDEFWPVLLIGAGLDLLVARNRPRFGLGLALVVLSVLGLYGLTYTEPNYEIYSEALAAPQMARVVVNERGSTLEIKPEILDGQTSIAGVVQATNIGLRELNPDSEHISIVLGQDEPFGGNKGPQTILVSMNHPVDFDWDLRDVTLNADLSTLQIGRVDAELDAGSAVINLAERGEYHFNIDATTLELNLPINIPVRIQRDDNATAFNLNRDLNIQQVDDDLYRSPDWEATPEEYRLDIYLSGSASSITIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9B370</accession>
    <name>A9B370_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4903"/>
    <dbReference type="EnsemblBacteria" id="ABX07533">
        <property type="protein sequence ID" value="ABX07533"/>
        <property type="gene ID" value="Haur_4903"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4903"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054927_2_0_0"/>
    <dbReference type="OMA" id="WNVTARY"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4964-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="295" mass="34255" checksum="42F68E0496D755FF" modified="2008-01-15" version="1">MNLQELMRQVRFIELKTTKLVTGVFAGMYMSSFKGRGVEFDEIREYEPGDDVRAIDWNVTARTGRPFIKRFVEEREMTVMLLVDMSASADFGTTRKLKRELEAELCATLAFSAVRNNDRVGMLLFTEEVERFIPPRKGRNHVMQIVRSLLTTDPEHRGTNITKALDYLNNVVEGKALVFIISDFRSLDNWIRPLRITARRHDVVAVRVEDPRERKLPKVGLVRLQDAETGQELVVDLRNEKLRDMFEKQAEAQHQSHVAELRALGVDHMSLQTDGRYADSLQSFFNRRMKRRERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B393</accession>
    <name>A9B393_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1412"/>
    <dbReference type="EnsemblBacteria" id="ABX04056">
        <property type="protein sequence ID" value="ABX04056"/>
        <property type="gene ID" value="Haur_1412"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1412"/>
    <dbReference type="eggNOG" id="COG1585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1364645_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1434-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010840">
        <property type="entry name" value="YqiJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07290">
        <property type="entry name" value="DUF1449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="200" mass="21789" checksum="290233C976CAE722" modified="2008-01-15" version="1">MKVWTTWYNLPFLISLGLGLVFAVLQIVGGFGDHDSDADIDSDGHDFFDGALDTLGVGKVPLMFILVSFLSLFGLIGLLLNAVAFQFDSVYPSWFFAVVLVLSLPLAFVGTSRTSRLFAKLAPENSLIVGFEQLVGRVGRVSSPTISVTYGRVEVRDPHGTVHTVFAQLATGEPLPTNTEVALVEYDQAKRCFIAKQFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3B1</accession>
    <name>A9B3B1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1430"/>
    <dbReference type="EnsemblBacteria" id="ABX04074">
        <property type="protein sequence ID" value="ABX04074"/>
        <property type="gene ID" value="Haur_1430"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1430"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004435_3_1_0"/>
    <dbReference type="OMA" id="LEYWVEA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1452-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1160" mass="129379" checksum="BB3EC8AC79C147C7" modified="2008-01-15" version="1">MQCTECLNLNPASARFCSQCGRMLADAPLPRSERRRVTVMFADLVGFSSIAEQLDAEAVHRLINACFDRLVPIIEHYGGVVDKFIGDAIMAIFGAPLAHEDDPIRAVHAASAMLDAIAELSQQEGLALGLHIGINTGVVIAGGIGSLGRQHYSVIGDAVNLAARLQDLASNGEILVGPETQRMTAHVFDFAALGEKAIKGRSEQVAVFKLRGLNPRPSSGRGIKGLQSPMVGRSNELDSLLAVTDNLAQQRGRVVIAVGEAGIGKSRLLTEWRNQSLEQLPQVVWYEARCLSYTQESAYALLRDLVRSLIGVSLNDGEDEMAAALHQIATALLADQADQVIPALSHLLLLPASRRFDELSPQALQALYITAVRRLVLAQGQHTPVIWSIEDIHWADEASVDVLQSLLQLHNDIPLVILATSRPDREVVGWRLVEAARDLKGLELNLAPLSLANGRELIANLLHFDGLPEHLRTAILNKADGNPFFVEEVIRTLIDREAIMHDGNSWVALEAINQIELPDSVHGLLAARIDRLPTELRQLLHIAAVIGRRFAIRVVAEVLGSTAERLSNSIDLLVDRELLRRDRTNPNGYLRFRHALVHEVVYSTTLQTERRRLHGVVGETLETLYPSRREELAAALANHFMHAEHPKAFEYALLAGDVAYRQYALREAIRHYERAHDLSHQYELPLAVVRGLYLNYARATELVGETKQALDLYNHVLERCDSENDTESLTIVLIERARLLMLPSLHRDLERSRSDTMRALDLATQQGDRQSEARCYWLLALIEGHLSRFTDAEPWGEKALSLARELGMRELQAYCLNDFHRVAINRGQHELAEQMLREAIELWRSLNNLPMLADSLSGMADFYYSRRDLEQAVRYAREAERLSVMIGNAWNLGFSRSVLGGIALETGDIQQALHMFQSSIEQSSISGPIMLNMYSRTELLRLYRMLGDYASALAVVDAAEAYLEQINDQALSTLRQLTAALRLLISLEQTQPEPAAMAEAMHQVLAFDLGDQQVIAGVMLRVAHIELSLKLSEYAHGERLLEQVVEQLSSLWFGTSLVVNYRARLAAAQGKISEALQLSEGLINEQPAGDVHDLWRFHAWRAEWLETQGQSDQALTERQQAQRLIRHISSNILRDELRDHFLGMPLVQATLQEPSSSFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3H6</accession>
    <name>A9B3H6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_2910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_2910"/>
    <dbReference type="EnsemblBacteria" id="ABX05548">
        <property type="protein sequence ID" value="ABX05548"/>
        <property type="gene ID" value="Haur_2910"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_2910"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053828_0_0_0"/>
    <dbReference type="OMA" id="WCAACDW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-2941-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="150"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX05548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="420" mass="47576" checksum="2B59695300F8A73C" modified="2008-01-15" version="1">MREFMQQQCPQCQRQLAFNPAYLPWCECGWNIKPRSLPETYGMFDKIYTNVSRRLGNQMLRQMQSLNDLKPRWTFGKVVVGLMAGLIHGFTLLILVLGVLLIFDGWPNPFAVVFGVVLLGMVWLLRPRLAKFSKDELILTPKEAPTLFNLLNQMTTQLGAKPIEVVVVDERFNASFSSLGWHRTPVLGLGLPLWLALSNQERVALIAHEIDHSINNDINRSFLIHSAINALATWVQTIYPVELVQPELGLKGFLLLPFNLLLRGFCWLLLGWMRLMVLLAGRESQRAEYLADYKAAELGGSAAAIDLLDRIHLDDSCHLAIQRAVLSPAKPHILQYLAEHITTIPDHERERLRRVARLEGSLLDASHPPTAQRIEFLSTIAPQQATIKPETNIMTAITNELLGYESQIIQRLRSQWISIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3T8</accession>
    <name>A9B3T8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_3438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3438"/>
    <dbReference type="EnsemblBacteria" id="ABX06074">
        <property type="protein sequence ID" value="ABX06074"/>
        <property type="gene ID" value="Haur_3438"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3438"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155828_0_0_0"/>
    <dbReference type="OMA" id="HIIADHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3475-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="121" mass="13636" checksum="4A851FB146945868" modified="2008-01-15" version="1">MNQPQVESLMFILNDVDLLNEVLRVWEEHGVRGVTVLRSTGLGRIGNALYRDDAPLFPSLRELLEDDEMHHFTLLTVVQSSQVEQLVAVTEQITGSLNNPNTGLIFTMPINRVFGGTRNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U3</accession>
    <name>A9B3U3_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 5">Acylphosphatase</fullName>
            <ecNumber evidence="3 4 5">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Haur_3443</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4 5"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3443"/>
    <dbReference type="EnsemblBacteria" id="ABX06079">
        <property type="protein sequence ID" value="ABX06079"/>
        <property type="gene ID" value="Haur_3443"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3443"/>
    <dbReference type="eggNOG" id="COG1254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141932_3_2_0"/>
    <dbReference type="OMA" id="ISWCYIG"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3480-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ABX06079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="92" mass="10291" checksum="FAC4CBE2C647DA05" modified="2008-01-15" version="1">METTRAHVIVTGTVQGVNFRATCRDQARLAKIGGWVKNLPDGSVEAIFEGSQAGVQRMISWCYSGPIHAKVQHVEVTWQEPTHREPTFDIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3U6</accession>
    <name>A9B3U6_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Haur_3446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3446"/>
    <dbReference type="EnsemblBacteria" id="ABX06082">
        <property type="protein sequence ID" value="ABX06082"/>
        <property type="gene ID" value="Haur_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3446"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_104_15_0"/>
    <dbReference type="OMA" id="SGMNAYL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3483-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="214"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="295"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="540"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="663"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="258"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABX06082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="791" mass="88798" checksum="432162AD13527759" modified="2008-01-15" version="1">MKRGSVRRTMITIAAIILSLMTGLNIIGVVERSMLNNDIEYVIDLEDAERLAREISLYTQYQAHALDAYALGEIEEREHYTRYRQAFDDKRLELEQFFKNMQPNPETKTAFENVQKLSADYEDAGVAYLAQIDLRIQESAPTRSTAELAAWKILDEQADQLDEATQVLSDIIDDQSEALEATITKQNGRMIVALTGRSLAILVLLSLFVYYLLGRVGNQFKLVRDGAQRFADGDFTTDIPIRRYDEVGRLAAMFNTMAQTIRGQIERLEQAKDHAQRLQFVAEEANRAKSNFLANMSHELRTPLNAIIGYSEILQEECEDLGQTAMIEDLDRIRLSGRHLLTLINDILDLAKIESGKVEILPEEISLPQLLHDVRSTVDPMIIKNENRLVIESAAGLLTMISDETRLRQILVNLLSNAAKFTEHGRITLRVQPSEEEGWIDFSVHDNGIGMSNAQLSRLFQPFTQADASTTRKYGGTGLGLALSRRLAQLLGGDIRVQSELGVGSTFSVHLPQSVIDMAPVSLLDEAPVIISDANNNQPKVLIIDDDRNVHHLLSRTLKREGWSVLSAFDGENGLAMVRNHHPTAILLDVLLPGHVNGWEILAEIKADPKIATIPVIMHTIVAEPNQGVSFGVYDYLIKPVDRGQLLRTLRSCIDPQNAKTQLVLVVDDDHDSRAMLRRMLEGAGWKVYEAANGREALGALHSRPFGAMILDLMMPEMDGFETIAALQELEQFRDLPIIVVSAKELTEEERQQLEETVERVVSKGNVRREEILALVREQVRRRVEQPPTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A9B3X2</accession>
    <name>A9B3X2_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_3472</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3472"/>
    <dbReference type="EnsemblBacteria" id="ABX06108">
        <property type="protein sequence ID" value="ABX06108"/>
        <property type="gene ID" value="Haur_3472"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3472"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015664_0_0_0"/>
    <dbReference type="OMA" id="YIAMKFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3509-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="14"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="656"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="802"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="836"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABX06108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="916" mass="101079" checksum="B876E7F0AAF53128" modified="2008-01-15" version="1">MQDPQLIGRMLNHFKIVDKLGQGGMAMVYRAYQENLNRTVALKLLPPEMTFDQSYIARFQQEARAAAGLEHSHIVPIYEVGQAEGFYYIVMKYIEGNTLKENIEQEAPMSVHRVLELLEPVGKALDYAHRKGVIHRDIKPSNVMLTPEGWVYLTDFGLARGGSSDSGLTQVGTVMGTPEYMSPEQAQGLTVGAASDLYALAVMAYEMLTKQMPFVANNAQAVLLARVIRAPRAPSDLIPTMPSAVEDVLMKALARTPEARYPTAAAFFEALRQASNGARPNVAAATPFAQNQPAQYAPTSPSSPQVYPPTPLSNQQAVAPHYPPTPLSNQQAVAPHYPPTPVSNQQVMPNYPPTNPSNQQVVIHSQSPYDGYVAANTQATRPAIMPNAAQPAQYNQQPISQPSPVAYTGATSVLRNKQKLTIWVGLGVLLLVAVVVGVILASGSDAEDIIAQGDAAFERRGGLIEAINLYKEATAADDESFEAHEKLAITYLMRGQTPDADQAIRQAIAIDANQASAHAWLSQVHSDNRQFNESLAEAEEAVRLDANHPLAYMARATARADVGNEQGDSELLADALADTNKAIELATNRSRFEQAMAYSAKGYVQWVTYQDQTSRDAGAGKEFVVDGIDNFNRAIGLQEQLPLLRNNIGYFYAEQARVALHLGEDETAAQRFEKAYQSFDDALALDPNYGLAFAGKGWTQIYERKYEEAQQFFDLALERNQRDPNALNGRALTNWWLGRNNSSDPQSDYAAAIRDYEAAIAEAPSWLSVYVDLGYVYLYDTKDTDKAIETFKKALERDPEYPNAIAGLADTYYDTRYYDEALKLYEQTINLQPDYATAYLGKANILYNNKDYDAAIDQYSTALDYNPSLKNAYIGKAYCYQAKGDIDEARQVLQDGLESVAYVDQSELQTILDKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A9B455</accession>
    <name>A9B455_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="6" type="ordered locus">Haur_4958</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4958"/>
    <dbReference type="EnsemblBacteria" id="ABX07588">
        <property type="protein sequence ID" value="ABX07588"/>
        <property type="gene ID" value="Haur_4958"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4958"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_0"/>
    <dbReference type="OMA" id="FNPMNNG"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="28"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX07588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="192" mass="21734" checksum="AD69E2C401DE9928" modified="2008-01-15" version="1">MTRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQLANIATPESRMITIQPYDQGAIKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKELVKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDERRGQEELQKLTDRFQKEVETIGTTKEAEVMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B469</accession>
    <name>A9B469_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_4972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX07602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07602">
        <property type="protein sequence ID" value="ABX07602"/>
        <property type="gene ID" value="Haur_4972"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4972"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_996668_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5035-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="279" mass="32238" checksum="AD6B79BEFE516CFF" modified="2008-01-15" version="1">MTKPDDLTDIVADLNQQQCWNLDGAGCQLLCQRSCEILQRNPIPNPAKFADVVVNVYHDYATVAAACDPQHPSHELIWVSIMDEILSWYRCKRFSLGNGSQLCEHSPDLVAYENVKRSLPQFRFEARLRSYIHTIADRAIIHWWRAKDAKKHGGSGGRRIHESSNVYTPKPQDQTYYLSQSHGRDHQRELGDTIASPDLSPDEHVERCELQRHMAAEVHAMVDDPLYPIAQQYWYALLCEDNNITALAKQLGLQANDLYNLRDRLRRRCKPFLVQWFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4C2</accession>
    <name>A9B4C2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX02679">
        <property type="protein sequence ID" value="ABX02679"/>
        <property type="gene ID" value="Haur_0027"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0027"/>
    <dbReference type="eggNOG" id="ENOG502ZSJ7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_979239_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-27-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX02679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="284" mass="32324" checksum="AEBC4BA7F1D5379F" modified="2008-01-15" version="1">MSHILPAWHRELRRNQTLNQWGFRWHSQRRLSRTPARADGLISLGSCPSVTTRHTRASILLDPSQPQQLWLDFCGEPDAPRLSCEPSFDALSLVYQRYFQRFNGRPQSRGINLLRQVVQLRSQPAPFDLATFLGDGYHQFHLFLGLIDDQTIIELENSMVFNPWLSLQALALDSGSGCGYSQYRTAFSGSILTMEFNRQFVTKDAACIARIAYHPVPVAEQASVQRWQMQNPANVVATLPQAVPFDVLGLYHHLDWQWWQTAEHAQSMAAEGDKHAAIVVRLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4D3</accession>
    <name>A9B4D3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphate protein domain protein TPP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0038"/>
    <dbReference type="EnsemblBacteria" id="ABX02690">
        <property type="protein sequence ID" value="ABX02690"/>
        <property type="gene ID" value="Haur_0038"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0038"/>
    <dbReference type="eggNOG" id="COG1013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048564_0_0_0"/>
    <dbReference type="OMA" id="NTVHGRM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-38-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="62"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="348" mass="37840" checksum="0F7B131DF89D0865" modified="2008-01-15" version="1">MATTKATPKPKINLLGFEQGEYKGAPSTLCPGCGHDSISSRIVSVCFELGVQPYQVAKFSGIGCSSKTPAYFLGRSHGFNSVHGRMPSVATGAIVTNRNLIGLAVSGDGDTGSIGMGQFKHLVRRNVPMVYIVENNGVYGLTKGQFSATADIGQKLKYAGLNELPPIDLCAEAIIGGATFVARSFAGDPRQVEALLKAALSHRGLAILDIISPCVTFNNHEDSTKSYAYGKEHEERLHDMTFIRAQEEITVDYEEGEAIPVKMHDGSTIVLKKLENEYDPTNRVAALARLDAARENQEFITGLIYVNQNNNRTIHDLLHMDEQPLSQLSAEQLRPSKEALESVLADLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4E5</accession>
    <name>A9B4E5_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA_ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0050"/>
    <dbReference type="EnsemblBacteria" id="ABX02702">
        <property type="protein sequence ID" value="ABX02702"/>
        <property type="gene ID" value="Haur_0050"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0050"/>
    <dbReference type="eggNOG" id="ENOG502Z95W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1286998_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-50-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_ligase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="217" mass="25092" checksum="01FD8A068C366972" modified="2008-01-15" version="1">MLYYPKMPDSRNAPLTRCWAFEKYDGTNLHWDWDREAGWHRFGTRREAFELTSHGIEQFSQAHAHIQAAPSLFQATLAQPLTEILLSHANYQSYKAYNEIRVFAEFFGPNSFAGLHKTSDPKQLCLFDVWLEGYGFIGPQQFVADFASLNSARVVYEGKLTGQFFEDVRNGKFGVQEGVVCKGGTGGSDLWMVKIKTRYYQARLKQAFAERWEDYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4H9</accession>
    <name>A9B4H9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1500"/>
    <dbReference type="EnsemblBacteria" id="ABX04144">
        <property type="protein sequence ID" value="ABX04144"/>
        <property type="gene ID" value="Haur_1500"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1500"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_0"/>
    <dbReference type="OMA" id="NITIKYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1522-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002735257" evidence="1">
        <location>
            <begin position="24"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="6"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="441" mass="49234" checksum="71F4D993918E53E8" modified="2008-01-15" version="1">MQRQRAVVIGASMAGLVAARALANHFQTVTIVERDAMSDETQPRKGVPQANHVHILLTGGFNVLQHYFPNFTNDLHSAGVPELNWSRDVQWFQGGSWKTRQPCKISFYPQARVTLESRIRGYVHQHPKIEFRSQTNVEQLLFDPSKTSVTGVLLKHADQTSELAADLVVDTTGRGSRTNQWLEAAGYPAPPKEVMPIDLVYVSQIFKKTNSPRNWQCLACHPSADSPRGAIIAPIDDEHWIVTLFGYLGQHPTPTSEGVLEFVKTLPVPDIYTTLAEATPAGEAMRFGYPQQAFQRYDKLKRFPQGFLVLGDALCSLDPVFGQGMTIACKEAHTLDQVLASAQGQQAATLAQAFFKQAQKIIDVPWLITQSEALRFKGMPGSRNPKIRFLQWYTDHVFWLSAQSTEIYQAFLDVMHLLAGPEALLRPKVVRGVLGRMFGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9B4W2</accession>
    <name>A9B4W2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3047</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3047"/>
    <dbReference type="EnsemblBacteria" id="ABX05685">
        <property type="protein sequence ID" value="ABX05685"/>
        <property type="gene ID" value="Haur_3047"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3047"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_0"/>
    <dbReference type="OMA" id="WLHRITI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3079-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="125"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="188" mass="21418" checksum="CA23880A0ECC67B7" modified="2008-01-15" version="1">MLAFQPSNQELNEASLVAGLRQRDDAAFNYFLQTFAPQLQRLARRYVYSDDEADDIVQESFIRAAEHINRFEGRSSLGTWLHRITINAALDYRRRQRPQTNLNELDERMSVSDLGDATLSAELSQYIYAALETLPTRQRMAINLCYLQGMTAQEASCSLGISPDTVYGYLQQAYPTLRRALACYMAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5C8</accession>
    <name>A9B5C8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase IV (Family X)-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0101"/>
    <dbReference type="EnsemblBacteria" id="ABX02753">
        <property type="protein sequence ID" value="ABX02753"/>
        <property type="gene ID" value="Haur_0101"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0101"/>
    <dbReference type="eggNOG" id="COG1796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1487121_0_0_0"/>
    <dbReference type="OMA" id="ATILEMT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-102-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HHH_8" evidence="1">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20062" checksum="7E58D17C05FEA283" modified="2008-01-15" version="1">MNNRAIAQILFNIATLLKRQNANPYRVRRYREVARAILRLRHSLTERALAGKALGINKLGASLTRKITVLAAQGQLDFYDDLCALLPPSQQRLLKIAGIGPILAERISQELGDVELATLLREAAYQRLTAIWGVGPQRADLIVSNMFPDDPPPPANAAHSARKSNIIYTQPTLWEYGQKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5S8</accession>
    <name>A9B5S8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Haur_1668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1668"/>
    <dbReference type="EnsemblBacteria" id="ABX04311">
        <property type="protein sequence ID" value="ABX04311"/>
        <property type="gene ID" value="Haur_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1668"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_2_0"/>
    <dbReference type="OMA" id="DTVSFHN"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1692-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="192" mass="21114" checksum="4B01B040D133F7DC" modified="2008-01-15" version="1">MTTPRIAIIISSTRQARLGEKVAQWVLEHAATRTDLAFELVDLREVNLPFFDEVASNAWVPSTNETAQQWQKTVGSFDGYIFITAEYNHSITAALKNALDYASPEWNKKPAAAVGYGGVGGARAVEHLRGIAVELQMAPTRTAVHIGGTDFIGIWQQGVALNDLPHLLPTLNTLFDELSWWAKALKTAREQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B5V1</accession>
    <name>A9B5V1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3106"/>
    <dbReference type="EnsemblBacteria" id="ABX05744">
        <property type="protein sequence ID" value="ABX05744"/>
        <property type="gene ID" value="Haur_3106"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3106"/>
    <dbReference type="eggNOG" id="COG2331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136025_1_1_0"/>
    <dbReference type="OMA" id="TYQYQCT"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3138-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX05744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="108" mass="11231" checksum="F951361ACE8D2AB5" modified="2008-01-15" version="1">MPTYVYACQACGAQFEQFQRFSDEPLTICPRCQGTIKRVFQPVGVVFKGSGWYINDSRSGNNNSASSKSSTPAPGSSDASSAAPAATSESKPEAPKAEASKSESSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B617</accession>
    <name>A9B617_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_3173</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3173"/>
    <dbReference type="EnsemblBacteria" id="ABX05810">
        <property type="protein sequence ID" value="ABX05810"/>
        <property type="gene ID" value="Haur_3173"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3173"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_569504_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3208-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX05810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="594" mass="65980" checksum="5C8B7C323AB6E862" modified="2008-01-15" version="1">MTQPSAPSTPLLHNRYRVQARLGENRLALVFRATDERLNRSVLVHLLRPDLLENAQLRKRFNDEAQGLAKRTHPGLLDVYDNGEVGNRPYMITEDVDGDLLRDRLPLAAERALEVLRQVVGAVAITINTQTPTPPIGSRSILLTSSDRAVLIEPWWLNNEELRGDMQLYRAPERLKGAAPDERSIVYSLGLLGYELLTGITPDPNAKDMPSIYQQVNGFVPSLVAALQVATAADPDQRTATVAALARDLAAVDSAADAPTKQLVRPLPALRDTMRDMRQNLAQRRTQPTPTPPPQQSPSASAAPNWNVAPPKPMMPPRQAPPPIQQQAVQQPPPQYYAPQPAPPVQQGISREELRSELRSEIRRETYRRGCLNFIWRRAFGLTLITLLVIGCVWGFTFGRNWLVGGAAKTWACERIPTWACNLLPGQQSETYIIIQDNTPVYTNQDRNSALVVSLPRNTEVVIRDPATNLTSNGWAKIEIDDYQGRRITGWIDSLNIAKPQPTVQPNEPDLPTTVGELVFKTLQESNVRTTAEYKSDGSNIIMAIPANTRVIAPDPDAIVTQGGIVWINIVFEKDGQAMTGWISRDLLQQEETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6B2</accession>
    <name>A9B6B2_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3687"/>
    <dbReference type="EnsemblBacteria" id="ABX06323">
        <property type="protein sequence ID" value="ABX06323"/>
        <property type="gene ID" value="Haur_3687"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3687"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1298975_0_0_0"/>
    <dbReference type="OMA" id="WPAGNHI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3729-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="118"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="213" mass="22343" checksum="68820DBCF68E87E0" modified="2008-01-15" version="1">MNWYDLSDYGNNYKRGAVALGLIVVLFLLLNRPSTPTISAWRGENPSVAGLSGSAIQVGQGDTLVAPPGISSDQPWGNPVAANRVVMTQGYGVGSHAPAEVWGAIDLAVDGNGDGAADPAGSVGAPVRATMSGYIEVTADSWPAGNHIWVIGNEYKTGYAHLSEFKVQDGDYVERGTIIGTIGSTGSSSGPHLDYQIWHNGVNQNPLNYHPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6D4</accession>
    <name>A9B6D4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PilT protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf81 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0185"/>
    <dbReference type="EnsemblBacteria" id="ABX02837">
        <property type="protein sequence ID" value="ABX02837"/>
        <property type="gene ID" value="Haur_0185"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0185"/>
    <dbReference type="eggNOG" id="COG4956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050839_0_0_0"/>
    <dbReference type="OMA" id="TMPTDLL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-188-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="300"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX02837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="385" mass="42369" checksum="3316BED1CF4DACCA" modified="2008-01-15" version="1">MTISEKKAVAVNRNRLLSIDFWVRILGMVVLGYIGWYFGSSSASNPRTSDETLAMQLLTLSGAGLGLLISHRITLYPIRNINQRLRRSTAQELIALALGSLLGVMLAALLSIPLSQLPGLLGSYSPALASFFIIYFCVVAFEYHKKNLVNFGVSLQTPKVRAVKEAVPMRRTCLVDTSAIIDGRVLAVVRSGFLDGILVVPRFVLNELQLLADSSDDMKRMRGRRGLDMLEEIRKDDQLRLEMPNDDIANARGVDQKLVTLALQDGHALITNDKNLSQVAELQGVQVLNLNVLSDAVRPPVGAGEMLVVKVREEGREREQGIGYLEDGTMVVVEDARERIGDEVRVIVSRVWTNDRGRMVFGRIMGSAGAFYGGKNDAGNYPARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6E8</accession>
    <name>A9B6E8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0199"/>
    <dbReference type="EnsemblBacteria" id="ABX02851">
        <property type="protein sequence ID" value="ABX02851"/>
        <property type="gene ID" value="Haur_0199"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0199"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1677035_0_0_0"/>
    <dbReference type="OMA" id="HREQICA"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-202-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX02851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="165" mass="18436" checksum="D83D28937E37FBC9" modified="2008-01-15" version="1">MHGVLFDSFEHNRWATALLLQTCSDLSAEQLATTVVGSYGDIIATFNHIIRADARYLQHLSGKAPDWLINREETSDFARLQVWAEEAASNWAEFLTMPFDAEQIVTLVTGDYEIHGGALIAQALHHSNIHREQICAILTSLGIEPPDLQPWAYAHETGRGHNRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6G8</accession>
    <name>A9B6G8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_0219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0219"/>
    <dbReference type="EnsemblBacteria" id="ABX02871">
        <property type="protein sequence ID" value="ABX02871"/>
        <property type="gene ID" value="Haur_0219"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0219"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_0"/>
    <dbReference type="OMA" id="STLAICW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-222-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="37"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="347"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="380"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX02871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="582" mass="64429" checksum="EB16F6DD15D37CCF" modified="2008-01-15" version="1">MALSNSEFVVERSWKINRSTPLRWVWSHARRNLWWIIGLFIGAFGNALFAAQVPVVTGQAFEAVKAGDKNGLWWAALLIVGGQFLRAFVQLLRNFSSEVIGQRLERDVRDELYTSLLGKSMAFHDSQPTGDVMARATNDVREMNLMLNPGVNLVVGSAMFLIMPLIASPHPQLLVVPILYLVFYGLLVWHYLRQLKPVTTAVRQSFGELNATLAEAIDGVETVKATAQEERERNRFRTAVSKWRNAFVAQGNVEAVFLPVLLLGLGQGLGFIHSLILFRNGLINVGDVVSFNGLLLLFGFPTFTAQFAYSQLSSGLAGGRRILELITTETELDENAQGYAEPMRGEIIFENVAFGYHSDVDAVQKVSFRIAPGQTVALVGQTGAGKTTLTKLLNRTYDTREGRILIDGVDVRDWNLAALRRQISIIEQDIFLFSRSIADNIGFGVPNATREQIIEAAKAAQAHDFIGRLADGYDTIIGERGVTLSGGQRQRLALARAFLTDPTILVLDDSTSAIDSATEDRIQQAIEQASQDRTTILITHRLSQIRWADLIIVIRKGTISAVGTHEDLMQQSEAYRAIFAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6K7</accession>
    <name>A9B6K7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate transport system permease protein CysT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Haur_0258</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX02910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0258"/>
    <dbReference type="EnsemblBacteria" id="ABX02910">
        <property type="protein sequence ID" value="ABX02910"/>
        <property type="gene ID" value="Haur_0258"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0258"/>
    <dbReference type="eggNOG" id="COG4208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_0_0"/>
    <dbReference type="OMA" id="VFISGNM"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-261-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011865">
        <property type="entry name" value="CysT_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
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    </dbReference>
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        <property type="entry name" value="permease_CysT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="52"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="268"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABX02910.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
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    </evidence>
    <sequence length="279" mass="29922" checksum="7C9FC8B1339C9F2D" modified="2008-01-15" version="1">MTTQTIERTAPRLPWGRWSIRGAALTYLAVFLVLPLIVVVVDGLGAGVESIVSVVSSPIARHAIWLTIWTGLVMSLINAVMGLLTAFVLVRYEFPGKTLLNAVVDLPFAIPTLVTGVMLVILYGPQAAIGGWLNQQLGWQVIFAPSGIILALLFTSFPFVVRSVQPVLINLDRSSEEAAATLGAPAWQIFWRVTLPALLPALVSGTLLSFARAIGEFGAIVVVAGNIPLRSQTAAVYVYGEIESGSQRDASAMSLVMLAIALGTMSLVDWLSRRREVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6R1</accession>
    <name>A9B6R1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ABX04370">
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        <property type="gene ID" value="Haur_1727"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1727"/>
    <dbReference type="eggNOG" id="ENOG502ZF5I">
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    <dbReference type="OMA" id="EIGICFW"/>
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    </dbReference>
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        <property type="entry name" value="DUF4386"/>
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    <proteinExistence type="predicted"/>
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            <end position="57"/>
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        <location>
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    </feature>
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        <location>
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    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="247" mass="26769" checksum="79B4381C79349162" modified="2008-01-15" version="1">MKLQTGRISLPHTAEQPQPDLAGLRFKSRMAGAIYLLIIIGGLFAVGFVPAALIVVNDAAATALNIQTQPSLYRMGLAVHLIIALCNIPLAAIFYDLFRRANQSLARMVLFFILVAVAIESVNLLNHFEPLILLQSTRYANGMPTEQLYLHAASTLELETTGFNLSLAFVGCYCLTAGMLILRSRILPRFVGVLLALGGAAYVINCFISILAPHIAASLFPFIQIPSFLGEASICLWLLIKGVKVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B6Y1</accession>
    <name>A9B6Y1_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Haur_3212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
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                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="6"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3212"/>
    <dbReference type="EnsemblBacteria" id="ABX05849">
        <property type="protein sequence ID" value="ABX05849"/>
        <property type="gene ID" value="Haur_3212"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3212"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_4_0"/>
    <dbReference type="OMA" id="GHMGFVL"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3247-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="404"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="134"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ABX05849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="517" mass="57305" checksum="A4A5C5EA153598CB" modified="2008-01-15" version="1">MTNTNDLGFTILSLVVFLPAVGAIILAFMRGQRGAARIFALGWSTLVFAVSLPILFNFKHDAAGLQFYEYFNWIPDWGVRYELGLDGISLWLVLLTTFVTPLAIWSAWNVEEKTNNFLMLILLQEMGMLGVFLAQDLFLFYIFWEFTLIPMYFLIGMWGGKRRIYATVKFFLYTFAASVFMLIGIIALGLLNYKYLAQQGLPTDTAFQVQTLMANINQFGLSDTELKLLFLSFFVAFAVKVPLWPVHTWLPDAHVEAPTAGSVILAAVLLKMGGYGMIRFCVQLFPQIAQEWARPIALLAVIGIIYGAVLSYAQSDIKKLVAYSSVSHMGFIVLGIFALNEVGLQGAVLQMINHGLSTGALFLLIGMVYERTHTRELADYGGLWKVVPVFVYFLLFATMASVGLPGLNGFVGEFLIMLGAFDSPIGWTFTAFAAVGVILAAVYLLKMFQGIASGPFSERRTPHLSDLTRREVAILLPLCILMLVIGLYSSYFTRPMETTIKALEAFVANAAPLIAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7D6</accession>
    <name>A9B7D6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_3783</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3783"/>
    <dbReference type="EnsemblBacteria" id="ABX06419">
        <property type="protein sequence ID" value="ABX06419"/>
        <property type="gene ID" value="Haur_3783"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3783"/>
    <dbReference type="eggNOG" id="COG2009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1924683_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3825-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045281">
        <property type="term" value="C:succinate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039023">
        <property type="entry name" value="SdhC_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41910">
        <property type="entry name" value="PTHR41910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="131" mass="14471" checksum="44DF5312D7680665" modified="2008-01-15" version="1">MSTRTILDRYQTSASYLARILLRFSGLLLTVYMLTYIWELSTVIRTSDEPAGTAAAAFNTAMAAYNTTFWHITHAVVVALVVLHALTGLRVLTLEAGFGARFQRASFWLSLVLTVALFVLLFIKIIANLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7N5</accession>
    <name>A9B7N5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1770"/>
    <dbReference type="EnsemblBacteria" id="ABX04413">
        <property type="protein sequence ID" value="ABX04413"/>
        <property type="gene ID" value="Haur_1770"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1770"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_18_4_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1798-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="133" mass="14717" checksum="106413333C15B021" modified="2008-01-15" version="1">MNQATQWTDGAISAITLFVPDSTMQQTSQFYQQVFGLPMVFSDEHSMVFQFGSTLINLLTESAAVELLAPMAVPKNDSRALYTITVANTDQIYAELRSRGVEFLNGPIDRAWGVRTASFADPAGHLWEIAQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Q4</accession>
    <name>A9B7Q4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1789"/>
    <dbReference type="EnsemblBacteria" id="ABX04432">
        <property type="protein sequence ID" value="ABX04432"/>
        <property type="gene ID" value="Haur_1789"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1789"/>
    <dbReference type="HOGENOM" id="CLU_1487123_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1817-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="181" mass="20340" checksum="7033BEB0105CEF9C" modified="2008-01-15" version="1">MIQQLLESVGALLHYHLFDNDPAAKAQVLIGIPATNPPAKLPSVAIYSTPTSFGMKQQDDQAWREFSQSCTIAIYTKEPAQAERWLSLSIGAVLLSQTELLHHYNQQNPVRYRSSVVESLHQIYSIQLLGAEPQAASDCYQWQIQLLVHGQFQAKLRQPVEADYIREVLLQLNSSDPSLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7R4</accession>
    <name>A9B7R4_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3644 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_1799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04442">
        <property type="protein sequence ID" value="ABX04442"/>
        <property type="gene ID" value="Haur_1799"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1799"/>
    <dbReference type="eggNOG" id="ENOG502Z8HD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051002_0_0_0"/>
    <dbReference type="OMA" id="FPYREES"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1827-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022104">
        <property type="entry name" value="DUF3644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12358">
        <property type="entry name" value="DUF3644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3644" evidence="1">
        <location>
            <begin position="153"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX04442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="438" mass="50971" checksum="D25DCC74B6F86A9C" modified="2008-01-15" version="1">MTTSSIVTERKESVRQCLISFGFPEDTEYSYELLTLSYFPSKHSKKTLAFLILTYKQECPVSILKRVSDQPAGIVRSLRDKGFVFKSNPNDPSEFQYQNQDGIQCRSIESFDPHKIKVGGRAKALLSKALAAVISSIEIYNKPDFRYREETFAILLVNAWELLLKSKIMADNNNQISSIQVFDSSGFPKQTRSGNIMTIDIIKALNMLSSQGKINKFCTDNLVILVELRDNSIHFINKNTELSKKVLELGTASLKNFVSIILEWFDEDLSHYNFFLMPISFFHVDETRNNIFSSDKELNKLISFIYNKELNNKYEEDSDYSITLAYEVKFKKVSTANISITTNKEDTAVRVYIDEDEKIKNQYPIDSNRLKEILASRYIDFKANKRYHQIRKSLENQEIYGERYCCIRYLNSITKKGTHKKFYSTEIIKEFDKHYQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7S9</accession>
    <name>A9B7S9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_1814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1814"/>
    <dbReference type="EnsemblBacteria" id="ABX04457">
        <property type="protein sequence ID" value="ABX04457"/>
        <property type="gene ID" value="Haur_1814"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1814"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_491571_0_0_0"/>
    <dbReference type="OMA" id="WAGYILE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1842-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX04457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="554" mass="58368" checksum="B8319896DC58CC9A" modified="2008-01-15" version="1">MKTTMVFRRAVLASIGTIVVSSLLVVNANSRGLLAQTLPNPIDFHPVVTYSSPSRPCELGRGDFNGDGFVDLATANQASSEVQIFLNNGAGAFPTHTTYSVATPCGIDVGNVDGDNDLDIVVTKQTSNQLGVLLGNGDGTFQIAQSFSTGARPTDVILRDLNQDTELDAVITNQDSQGVSILLGNGNGTFANQTIYTVQASPTLEAVGDLTGDGYADVVVANAGSDSVSVLINNANGTFSSAVHYGVGNIPHSAGIGDIDGDNDNDIIAVNRWEQSMTRLINNESGSFTPLAPTIFLQGPSDIEITDLDGDGVLDILATNTVNDVDPGTVSIYFGLGNANFSSPQLVTSGVHPTSLIYADLNNDGLVDIATSNFYGNSISVLLRRVPAATSTPTITPTATSTPTATNTPTATPTSQPSVTPVAGSSTTFLPLVTDSRPIFPIVINAVAQPLIPITQQGQIYYTTTLTINTPLPTTGRFYLSSRPDAIAEVRVDDQMTVWADNAVLYERSLTTPQVVEISRSELTSWLDQELTITFRDVAGSVYGNSAVWLIWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7W6</accession>
    <name>A9B7W6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_1851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_1851"/>
    <dbReference type="EnsemblBacteria" id="ABX04494">
        <property type="protein sequence ID" value="ABX04494"/>
        <property type="gene ID" value="Haur_1851"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1851"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_32_0_0"/>
    <dbReference type="OMA" id="SHQAHFI"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1880-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="246" mass="26422" checksum="31960AD5AC46CA81" modified="2008-01-15" version="1">MPQDFSGQVALVTGASRGIGAEISRQLAQRGADIVINYRSKASRAEAVASEITALGRTALLAQADLTQINDLITTQTQIQQAFGKLDLLVLNASGGLEKDKPASYAMDLNLTAQVQTVETMLPLMQAGSCIVFVTSHWAHFYGERPIIAGYEPVASSKKAGEMALRERIDQFTQRGIHFYVVSGDMIEGTITPKLLDRAQPGFLAARKEHSPEPIPTIEEFASAIVATAADRSQANGHTVFVGPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A9B7Y9</accession>
    <name>A9B7Y9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_3285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX05922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3285"/>
    <dbReference type="EnsemblBacteria" id="ABX05922">
        <property type="protein sequence ID" value="ABX05922"/>
        <property type="gene ID" value="Haur_3285"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3285"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035002_0_0_0"/>
    <dbReference type="OMA" id="DVAHPAW"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3322-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="18"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX05922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="405" mass="43193" checksum="2FC3985B743A9856" modified="2008-01-15" version="1">MLSPKAHPAINQTGLRANLGQFSLLMLINAMVGGMIGLERTILPILGSQTFGLSSTTTVLSFIISFGLVKALMNLIAGVLADRYGRKRILVLGWLVGLPVPWMLIYAPSWGWIVAANVLLGINQGLAWSMAVVMKIDLVGPQQRGFAVGLNEFTGYMAVAITAWLTGYLASSYGVRPVPFYLGIGYAIIGLGLSIGLVRETHGLVQQTTSTNSNFWQLVQQTSWGNRTLFGASQAGLINNLNDGMAWGILPLFFASYGLELPAIGLLKFMYPAVWSVGQLITGPLSDKLGRKALIVQGMLLQAAALGLIVNTTSFGWWLLSSIGLGIGTAMVYPTLIAVVSDNATPASRARVLGIYRFWRDLGYAIGALLAGIIADWLGMAWAIGLVAGLTAISSLLAHLNLNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A9B878</accession>
    <name>A9B878_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin</fullName>
            <ecNumber evidence="1">1.16.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_3795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-storage protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide</text>
            <dbReference type="Rhea" id="RHEA:11972"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:78619"/>
            <dbReference type="EC" id="1.16.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferritin family. Prokaryotic subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.2" evidence="1"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3795"/>
    <dbReference type="EnsemblBacteria" id="ABX06431">
        <property type="protein sequence ID" value="ABX06431"/>
        <property type="gene ID" value="Haur_3795"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3795"/>
    <dbReference type="eggNOG" id="COG1528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065681_1_2_0"/>
    <dbReference type="OMA" id="CEDKGFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3837-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01055">
        <property type="entry name" value="Nonheme_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041719">
        <property type="entry name" value="Ferritin_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="PTHR11431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0409">Iron storage</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX06431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="164" mass="18745" checksum="60D5EAA7D577E5D7" modified="2008-01-15" version="1">MINPTIEAAINDQIKHEFESAYLYLSMSAYFESVNLSGFAHWMRLQYEEETVHAMKLFDYLHDRGGRAVLQAMAQPQSSFNSSLEVFEMALHHEQRVTALINSLYDLAIKENDHATQIHLQWFITEQVEEEKSASDVVEKLKMAGDHPGALFLLNEQLGSRAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8I7</accession>
    <name>A9B8I7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK domain protein ATP-grasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Haur_5021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="3 4">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="4">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3 4">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07651">
        <property type="protein sequence ID" value="ABX07651"/>
        <property type="gene ID" value="Haur_5021"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5021"/>
    <dbReference type="HOGENOM" id="CLU_055286_0_1_0"/>
    <dbReference type="OMA" id="CPMTFQE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5084-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0614">Plasmid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="130"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ABX07651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="339" mass="37450" checksum="08E8A4A6B3671C38" modified="2008-01-15" version="1">MILVLTSPDDTHADRVCDLLDQADAPWFRFDPAAFPHSAQLTVTTGATGLVQRLLVTRDHSLDLAQVTALWYRRPQAPVVEVPGIDPSHNAALAEECQHLVRDLWETLACLMVPASYWVIQRAQHKISQLQLATALGFELPPTMVTNDPSALIAFSRAHNGQIISKPCMGLALQRTGYYQYTRPVTRRDLAAAETIHASPMIFQKLVPKAVEVRITVVGDQVFAVAIHSQVSHHTRYDWRRYDHDHTPLTPHTLPPALAAQCVALVARMGLTYGAIDMILTPNGRYIFLEINPNGQYLWVESRTGVPISAAIARLLQTGTHRTVANLVVSEGGIACLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8J5</accession>
    <name>A9B8J5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase, MGT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07659">
        <property type="protein sequence ID" value="ABX07659"/>
        <property type="gene ID" value="Haur_5029"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5029"/>
    <dbReference type="HOGENOM" id="CLU_000537_7_1_0"/>
    <dbReference type="OMA" id="MFSIAAH"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5092-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006326">
        <property type="entry name" value="UDPGT_MGT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01426">
        <property type="entry name" value="MGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="408" mass="44839" checksum="2CFEC0DB2FB50EA3" modified="2008-01-15" version="1">MSTIIYLLPPAHGHVNPTLPVIQELVTRGETIICYNTAEFRVQIEQTGAHFRAYPPMEMTPVALSRLLQDGNLARITGLILRTTEHLLPFLLDAFAHEKPDLIVFDSIALWGKMAATILGVHAVASISHFVMDEHQLPFLDIVRLLGQVLPQMPAILFARRRLMNTYGTAYPSARPLFPMRGDLNIVFTSQELQPSIPLIDATFRFVGPAINPQTRSGTSMADELGQEKVIYISLGTIHTPQSSFVRTCFAAFADYPTRVIMSVGSQVASSAIGSIPANFIVRPSVPQLDVLQQTAVFITHGGMNSIHEGLYYGVPLILIPHQVEQLLNARIVTARGAGYLLTHQLTHTQITVPILRQAVDTVMADPHYRVAAQSLQGSLRATGGYYQAADAIQSYISESRMIVVTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8P0</accession>
    <name>A9B8P0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CRISPR-associated CXXC_CXXC protein Cst1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07704">
        <property type="protein sequence ID" value="ABX07704"/>
        <property type="gene ID" value="Haur_5076"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5076"/>
    <dbReference type="HOGENOM" id="CLU_032781_0_0_0"/>
    <dbReference type="OMA" id="LLFRIYE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5138-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010180">
        <property type="entry name" value="CRISPR-assoc_prot_CXXC-CXXC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01908">
        <property type="entry name" value="cas_CXXC_CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="492" mass="56683" checksum="75F1B0EC4AF70B65" modified="2008-01-15" version="1">MLKETGHPLVDVGFATIAAHVNKTNIKAVTAADLEKVAAYLEAEFVVNPLRSFLTVAFTSNAWFIQDAYNPDKPQLTDEQRTTRRATRKKLADAHLRQWQQPSTSEQRCVFTDEPAVGEVLSNTLTVGRAARAQIPLLQGDATINFFPNGNAGLPVSGIALLALQAFPLGSAKAGNGILVVHSANPRLTLNFAKTFYQRNKSKIERARIAGDDRVPGEVRSPKTLLIETLFEITAERENYDDDQITSIVAYNLNNGKTPSLAIYELPHEIILFMLEAKGHFPKQWNQLVHGAWEQASAASKKSNQHFEPRRNYFYEDMFDLPNNAKRFVRTYFLKMPYLGTLDDDNQSRYYLHDYYHLIDFPIVELFLRRIFLMDDLRIARIKHFGDKLANYVRAENGKRFFRAFASEYKYQDFRQRLIKASEDYVRSSQEPLFTIDEYVDVFERQYSDQAPDWRLSRDLVLIRMIEQLKDWLSRNPDAMPERPEPKQEQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8Q9</accession>
    <name>A9B8Q9_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase 28 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07723">
        <property type="protein sequence ID" value="ABX07723"/>
        <property type="gene ID" value="Haur_5095"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5095"/>
    <dbReference type="HOGENOM" id="CLU_085408_1_1_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5157-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="173" mass="19351" checksum="C6DBFBAF897158BC" modified="2008-01-15" version="1">MIFVSVGTRPEPFTRLVTAMDGVAAQINEAVMIQTGHTPCPVRYAHTRPWMNEADYHLMLQQARVVISQAGAGSILGARHHGRPLIVVARSRRFHECPDDHQYELAYAIEQLGYAQFVQDITPDALIAALNHVIDPGDTPILPSPLVATVHHYLTQWDQPAASWVQRFRRKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8S3</accession>
    <name>A9B8S3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV secretory pathway VirB4 protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07737">
        <property type="protein sequence ID" value="ABX07737"/>
        <property type="gene ID" value="Haur_5109"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5109"/>
    <dbReference type="HOGENOM" id="CLU_396273_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5171-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="338"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="695" mass="76418" checksum="EE6A88990D60DC8B" modified="2008-01-15" version="1">MTPPLLLHLHGLEVVNLHPHQWEVAIDRVRQALQSLVVDWRLISVVAPRSLAQRRQRIHDHLRLLDPSDPRHPRLTAQLLHLQDLEQHAMTSMTHYLVVWCPPSLAHTTVEHTLGRACGGATRLTSLPFLLGAPTVQLTAASCVADTPTGQRCWQGMLAERWHGSLSPLLFRPLLLEQTHAIIVVDALTMAPDRARTTMDVALQRLDAHAALNPTYDEARRHAVQDWQAASTHLERGALLHTVQVAVFVGAASPALARTHAQAARQALGSTISFSPMLGRQPDLLPLLGTRATATLDLPTTGHPMITAQLATLLPIYLAQRSQPPASALLAGVDEVRGTPLLLDLTALPALHGFFCGATGSGKSSYVATLGSRLVDDAGYQLILLDPQGAFAPLAAAYAGRASVNRVALDTLRLNLLDPIVDLQHDLVTQVLHVEEVLQWLLDGALTQLHRQTLRRVLSLVYATHAAPRLSDVVALLAEDTTGLRELLLPWTLSPFAEVFDQPSTMDLTLDPTTPVVIYDVSDAAMPDHIKQFFLILIASAIQREIRLRPRKAIIGIDEAGVLFANPLLASFAERLAKTARRFGAGVWVIDQTTHLLDTKAGAEIFENSFITVLGTMRSDQLPALRERFPMVTDAQLQWITGLGMTDAQRQERAGQYLIIVNETPYLIYNHLSHWEWQLLPQRAVLHTEVGYGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A9B8W3</accession>
    <name>A9B8W3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Haur_5149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="10 11">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="11" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="11">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="10 11">pHAU01</plasmid>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07777">
        <property type="protein sequence ID" value="ABX07777"/>
        <property type="gene ID" value="Haur_5149"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5149"/>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5211-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-0614">Plasmid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="663"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="747"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ABX07777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="1105" mass="121902" checksum="78EC39334CB990AD" modified="2008-01-15" version="1">MHLLDIQHKISRLMARFVEEVKSSTAMGHSDINRVAETVLIPLLGRVYECPSLQNLNSLHPNYPAVDLGDVARRIAFQVTTTPDSKKIKDTLTTFIAHNLHTQFDTVYVYILTEKQHSYSPAIFSTITGNHLLFDPKRHILDANDLLKQIATYHVDKAQQILTILEANFDTPIDPLAHALAVYGTLPLDYVPMARLDLPQASRIPFESSAYFVGREAELKALARAIIQTQPTVVVPAVTTGLGGIGKTSLVTEFAYRYGVYFHGGIFWLNCADANQVASQIAACAVGLKIDTTGMALDEQVQQVLYAWQSPMPRLLIFDNCEDPAILTQWKPTIGGCRVLVTARSDQWPTLTQIRLGLLSPVESRALLQRLCTRLTDTAADAIAEDLGHLPLALHLAGSYLNTYSHHTVEQYRTELTIAHRSLKGRGAFPSPTQHELDVEATFMVSVNQLDPNDPIDALALGMLDGAAWCAPSVPLPRYVILSFVPDGTDGDDAVDALRRLQALGLLDGIETVILHRLLAQVIHVHMGWSATLALVEQRMVAAAEQAHKTGIPKQMNPLEPHLRGMTLRVLDRDTEQTARLATNLGLFAQHQGWYAEAQALHERAFGIRRVLVGENHSSTAMSINNLAEALHQQGRYLEAQDLFERALAVREVVLGLDHPDTARSVNNLALVLESQGRYSEAQDLFERALAVREAVLGLDHPDTAVSVNNLASVLESQGRYSEARGLYERALEVTEAVLGREHPDTARSVNNLASVLARQGRYSEAQPLYEQALAVNEAVLGREHPDTARSVNNLASVLESQGRYSEAQPLYEQALAVREAVLGENHPDTAMSMNNLAMVLLNQGRYSEAQGLLERTLTVHEAVLGAEHPDTAMSVNNLAVVLESQGRYSEAQGLLERALAVREAVLGAEHPDTAMSVNNLAGVLESQGRYGDAQRLYERALVVTEAVLGAEHPNTARSMNNLAMVLLNQRRYSEAQGLLERALTVHEAVLGAEHPDTAMSVHNLAVVLERQERYSDAQMLYERALAINKAVLGREHPDTMTTMGSLAGVLERQRQYGKAQSLYEHAFAIRKRVLGLTHPDTQSLQRDVGRVQRLHLTTKKKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A9B902</accession>
    <name>A9B902_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid pRiA4b ORF-3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU01</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 1 pHAU01 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU01</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU01</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000876">
        <property type="protein sequence ID" value="ABX07816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07816">
        <property type="protein sequence ID" value="ABX07816"/>
        <property type="gene ID" value="Haur_5189"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5189"/>
    <dbReference type="HOGENOM" id="CLU_085055_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5251-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU01"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012912">
        <property type="entry name" value="Plasmid_pRiA4b_Orf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41878">
        <property type="entry name" value="PTHR41878"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="SSF159941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="189" mass="21342" checksum="8634ED5B16760A5A" modified="2008-01-15" version="1">MTLAASTPLIYHLKIVLRDITPQVWRRVQVAATTTIADLHAIIQTAMGWEDAHLHQLLIYGKAYGVYHDGGFSFADDPDQVRLADFRLRVGERFRYDYDMGDFWQHDIWIEHIRPAVPHRVYPHCHAGSGACPPEDCGGPPGYRALLRERTSWDMLDPLHAAMQLILERVQTFAAGGERKKLGGSGLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A9B954</accession>
    <name>A9B954_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5241"/>
    <dbReference type="EnsemblBacteria" id="ABX07868">
        <property type="protein sequence ID" value="ABX07868"/>
        <property type="gene ID" value="Haur_5241"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5241"/>
    <dbReference type="HOGENOM" id="CLU_1852451_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5303-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="138" mass="15121" checksum="932D9C4982DCD053" modified="2008-01-15" version="1">MARELEQFLGRGEEAAFWILTYKNVGSAILGGFMGSRVGQLMGTGGIVMLLSVVGVALGLGLSLNRRGLMWGRRLWLALLFYLRSAIKPRMIDAGDWYRVIEEREHAVGVRQAGQLVVAPRRMAAEAVAHGRPEGESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A9B976</accession>
    <name>A9B976_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07890">
        <property type="protein sequence ID" value="ABX07890"/>
        <property type="gene ID" value="Haur_5263"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5263"/>
    <dbReference type="HOGENOM" id="CLU_2523005_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5325-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="84" mass="9571" checksum="CD49513BB1E661DD" modified="2008-01-15" version="1">MKKEAESAMRLYHYLVDCPCDDAVWIRALNAILTDGSTIDRAMAHGFIVHPEQRYPVNRGVLHPTKRSMIPVLTVLWYTTIDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9A5</accession>
    <name>A9B9A5_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_5292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="1 2">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="1 2">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5292"/>
    <dbReference type="EnsemblBacteria" id="ABX07919">
        <property type="protein sequence ID" value="ABX07919"/>
        <property type="gene ID" value="Haur_5292"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5292"/>
    <dbReference type="HOGENOM" id="CLU_2023533_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5354-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0614">Plasmid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX07919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="122" mass="13326" checksum="BB5AC1C38EAD83A0" modified="2008-01-15" version="1">MPNGDMNIHQNHAVIGNNYIGQNFYIGSGVGGIDQRDLIPLLEEIRLNIVGLQKTGVIDDEKAIEAKHKVELAEVEAKKDEPAKKTLLERVTGAKMVLESVASASNLVIALTKATDLINQYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A9B9B4</accession>
    <name>A9B9B4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_5301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>pHAU02</name>
    </geneLocation>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of plasmid 2 pHAU02 of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="3">pHAU02</plasmid>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
            <plasmid evidence="2 3">pHAU02</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000877">
        <property type="protein sequence ID" value="ABX07928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_5301"/>
    <dbReference type="ESTHER" id="hera2-a9b9b4">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX07928">
        <property type="protein sequence ID" value="ABX07928"/>
        <property type="gene ID" value="Haur_5301"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_5301"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_43_3_0"/>
    <dbReference type="OMA" id="RPGFGTC"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-5363-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Plasmid pHAU02"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="59"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX07928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="275" mass="28122" checksum="1C8BEFB5F435ACE1" modified="2008-01-15" version="1">MSYTGANTGRITPPLFGTEVMMDFIQSSDGTRIAYEQAGTGPLLIVLGGAFNDRTVGIPLMEALAPTATVLTYDRRGRGASSDAPTYAIEREIADLAALIAHHGGTARVIGYSSGAILALRAVAAGLPITGVVLYEPPPTGRVGDELAPQLAALLAADQRGAAVELFQTVAVGLPATVVADLRHAPFRPALEAIAHTLVYDTLLLAALPDGLLAAVTIPTLVLAGDQSHPIMAATAQALAAAIPQGQYQLLVGEGHGITPAVVAPLIHAFFSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUD3</accession>
    <name>A9AUD3_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0401"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX03052">
        <property type="protein sequence ID" value="ABX03052"/>
        <property type="gene ID" value="Haur_0401"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0401"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062624_1_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-404-MON"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="PTHR12726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="402" mass="46263" checksum="0BB26E017E9CA2F6" modified="2008-01-15" version="1">MIKRIWIVLCGLMLGQRCWKWWQVWRFFGKPTPTAQHEPATTLVSLLQPILSGDPHLAICLRANLNAPSSYKREWLWLIDDDDRIAQQLCYGLQAEYAEQTIRIISLPAPAERVNPKTFKLIAGLQQAQGQIICVLDDDTSLPAYGLEQCLPWLDQAGVGLAFGLPYYRSFDNTWSSLVALFVNSNSLLTYVPYSQVSEPFTINGMFYAMRRDVLEQLHGFVGLEHILADDFAVAQRVQQAGLRLQQTSMRHAIRTTVTNAQRYRSLIQRWFIFPRESLLRHLNRRERSLLFCLAIVPTLFPLVLAIVSVLRPSQRQRWFAATYTLLGLISFIQIDQAYLEQATPRRYWLFVPFLELLIPVQLIQALLAPQRIVWRGHVMDVEKGGAFRFVQRRDDGSANGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUE6</accession>
    <name>A9AUE6_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0414"/>
    <dbReference type="EnsemblBacteria" id="ABX03065">
        <property type="protein sequence ID" value="ABX03065"/>
        <property type="gene ID" value="Haur_0414"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0414"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078469_3_0_0"/>
    <dbReference type="OMA" id="CAYLIRP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-417-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="220" mass="24296" checksum="691D19298BB5CFD2" modified="2008-01-15" version="1">MTVFGIREGTPAGDIVSYIQRKGSATVKELEDALAVSTTAVREQLTHLTNQGLIAPTKIRQGPGRPSYRYTLTAKAQSLFPKGYDVLLNVLLEEILATEGPEGMAQLLSRVGTRLATLYTGDHPANVALRERLMQFVYTMNRKGMSINVAESPGGGWVVSEYACPYFEVAQTHDSLCSMERQMMETALGHEVEIQRRMVEGHNGCHFVIKADEIGIEKHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUK4</accession>
    <name>A9AUK4_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Haur_1888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
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    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="316274.Haur_1888"/>
    <dbReference type="EnsemblBacteria" id="ABX04531">
        <property type="protein sequence ID" value="ABX04531"/>
        <property type="gene ID" value="Haur_1888"/>
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    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_034004_1_1_0"/>
    <dbReference type="OMA" id="DAQFAFE"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1917-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
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    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="15"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="172"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ABX04531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="366" mass="40655" checksum="A4C68D27AF3D8A92" modified="2008-01-15" version="1">MTSPTSLDTTPQLDDFDYVEFYVGNARQTAHFLRTAFGFKPIAYAGLETGVRDRASILLQQGAIRLIITEALDPESPIADHVKLHGDSIKDIAFTVANVHSAFEAAVKRGARPILEPVTIESPQGSIIKATIGTYGDTTHSLIQRVDLADNAFPQFQPIENPAHVIDGGFSVVDHVAISLEPGRLAEWVDFYINVLGFHQSHEENIVTEYSGMNSRVVQNHAGTIKFPMQEPIQGKRRSQVEEFLTFHHGAGAQHLAILTDDIIHSIQTLRANGIEFVRTPATYYENLQERVGLIDEDIAMLRDLHILVDRDSSGYLLQIFTKPLQSRPTMFFEIIQRKNAIGFGSGNIKALFAAVEREQALRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        </submittedName>
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    <organism evidence="1 2">
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    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
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                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX04590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ABX04590">
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        <property type="gene ID" value="Haur_1947"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_1947"/>
    <dbReference type="HOGENOM" id="CLU_2649498_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-1976-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX04590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="76" mass="8762" checksum="F9C71BE614480266" modified="2008-01-15" version="1">MDWQALSDRALIAEIDHALRHRAHAALKLWQLIAPQIDPAQQAYGDLLQRYLEQNIELAEAIHQWLLVQIAKQIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A9AUU9</accession>
    <name>A9AUU9_HERA2</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Haur_3903</name>
    </gene>
    <organism evidence="1 2">
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            <taxon>Bacteria</taxon>
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            <taxon>Chloroflexia</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
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                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
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            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3903"/>
    <dbReference type="EnsemblBacteria" id="ABX06537">
        <property type="protein sequence ID" value="ABX06537"/>
        <property type="gene ID" value="Haur_3903"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3903"/>
    <dbReference type="eggNOG" id="ENOG50349BS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1412938_0_0_0"/>
    <dbReference type="OMA" id="LITWERR"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-3945-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX06537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="172" mass="19054" checksum="18EEEE56132A25AD" modified="2008-01-15" version="1">MRFPKSQALQLHSCFEELIPGRMHTSGQRFLPLIVLGFKQVRLGVVDRHNHVNQSHAGRYGTARLVFQLSRVALQPADTQRMGIEPEVGNGLSTMPLAYGCIQDLITWERRDDLGYAVSYVEAIIAVGVGSIGLRTTLTGQNVAKLPNEQLQTGDWVVLSNSRIDILGFEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A9AV65</accession>
    <name>A9AV65_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_0492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0492"/>
    <dbReference type="EnsemblBacteria" id="ABX03143">
        <property type="protein sequence ID" value="ABX03143"/>
        <property type="gene ID" value="Haur_0492"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0492"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_7_0_0"/>
    <dbReference type="OMA" id="HADTVWP"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-498-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017150">
        <property type="entry name" value="Pept_M20_glutamate_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037238">
        <property type="entry name" value="Carboxypeptidase_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="182"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX03143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="376" mass="40537" checksum="23E09ED14D5EDC66" modified="2008-01-15" version="1">MPRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGKPQADHLLASWPGEGEPLLIVGHVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTCAALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQARGCRAALIIESAEEGGWLKTWRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGGTATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPATMALYAAAEQIANQLDLPIKASGTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSISQFAPRAALLARLIETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVA7</accession>
    <name>A9AVA7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0537"/>
    <dbReference type="EnsemblBacteria" id="ABX03185">
        <property type="protein sequence ID" value="ABX03185"/>
        <property type="gene ID" value="Haur_0537"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0537"/>
    <dbReference type="HOGENOM" id="CLU_902464_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-546-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="308" mass="35459" checksum="9F518A4F6D47E2D6" modified="2008-01-15" version="1">MTPAGFSDETIIKEWNDVLHGVRLMQRYDPSYYEQIRDEPLTLVKGKSCFIRMAYLVEDLVSTTMNFQDYMEWRQEDFDPYDDADDIANDDPALSESYSLDLRFEIAGQWLDETPLAVFGLPIHAGEAGDMFHLAMWLTRYPFHTTPYDVMRFDGDRYFVKDKEIFQALKTFDPLPEHIHIHGLIQELNRKKIYGFELGTLIQYALRITGDVFADVSMAELEVGGWDDGIDWANPDMVASVQDRQRRADALCSQFHDFAAWLDRNNEYAIDILLNIYGAAAVVLANDTQRPATLMELVNANDEVPQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVL7</accession>
    <name>A9AVL7_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gatA</name>
        <name evidence="9" type="ordered locus">Haur_3985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_3985"/>
    <dbReference type="EnsemblBacteria" id="ABX06617">
        <property type="protein sequence ID" value="ABX06617"/>
        <property type="gene ID" value="Haur_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_3985"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_0"/>
    <dbReference type="OMA" id="EVSCPHF"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ABX06617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="489" mass="52518" checksum="7BFB63B0691F5F3C" modified="2008-01-15" version="1">MREDVIMALHELTIAEARAQLDRGEITSVQLTEALLERIAALEPTLHSFLTQTPDLALQQAQAADERIKAGNATSLTGIPLGIKDVIVTKDVRTTCGSKVLENWVPPYDATVVSKLNEAGTVTLGKLNMDEFAMGSSNENSAFGGTRNPWDTERVPGGSSGGSAAAVAAGQAFGTLGTDTGGSIRQPAALCGIVGLKPTYGRVSRYGLVAFASSLDQCGPFARTVEDVALLLETIAGHDPKDSTSANLPVPDYRASLTGDIRGLKVGVPSEYFVDGMEPGVEKAVRTAIEQIKDLGAEIVEVSLPHTKYALPVYYIIAPAECSTNLARFDGVRYGVRLEGNGLFDEIESTRGQLFGAEVRRRIMLGTYALSSGYYDAYYRRAQQVRTLIRRDFQEVWSKVDLLAAPTSPSVAFKIGEKADDPVAMYLSDVCTLPINLAGVPGLVVPCGFSDNLPTGLQLIGKPFDEATLLRVGHAYEQNNSWHKQHPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVS8</accession>
    <name>A9AVS8_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Haur_4046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX06678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_4046"/>
    <dbReference type="EnsemblBacteria" id="ABX06678">
        <property type="protein sequence ID" value="ABX06678"/>
        <property type="gene ID" value="Haur_4046"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_4046"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047530_1_0_0"/>
    <dbReference type="OMA" id="RVYLDGF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-4089-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABX06678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="319" mass="34355" checksum="24659378FC25AD7E" modified="2008-01-15" version="1">MACFLRTFVRLGPVIVNMRLLGGSVATTAPSSTPFPMDEYQHADNHHHGTRQSMTNAGQNRLGLRFREAREARGISLAQASSETRIIQRYLAALENGEYHHLPGDVYARGFIRNYAQYLNLPADELIDLYRIERGASTPIRIVPAAVPPRRNTIFLPSLWTVILVVLALVVIGYLTLNALGLTTINSTSVSGGATTTLAIATPTLLATPTAQPTNPDGSVPSPINPLATPTVTITPTQDVPVQVVLRIDGGSSWLQVLVDGQNTIEGIQNNGWTQTFSAQQTIQVKAGNAAVVEVIHNGKPPVRMGAPNQVVTTIYTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVV7</accession>
    <name>A9AVV7_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Haur_0547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0547"/>
    <dbReference type="EnsemblBacteria" id="ABX03195">
        <property type="protein sequence ID" value="ABX03195"/>
        <property type="gene ID" value="Haur_0547"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0547"/>
    <dbReference type="HOGENOM" id="CLU_487262_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-556-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABX03195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="561" mass="60898" checksum="6DC4635515AB1C7F" modified="2008-01-15" version="1">MSMQYAISLYDPFTNVQLARFDRQVTDATLSTNGLTVSVRLVPFIAKTLYAQARLLTAVVQRSDGKTLRYRTVTLRLIDQGLAIECHNLIVTLDDLEYDGWWSVTKLDGWLPVETASSTPERWEMRHDDGTISLSPRKNEQFSNAKGIGRQSLFIPANLNTTGFQVIQFDWRSKGPTNWLATFLAAERDYSSQTGATTIALGNGTAQTGSLCFTFAARPLVSVAMYYNAALATYIGETGDDYLKISNLRVATVTTNMVNTTTSGAIAIGTAFVPVASTLNIAVGQRLTIESGGVNSESVVVLAVNATQFQAAFTKTHVLGVTVRGIVVTDKEIVEDVLSRNLTTNPGSGIKQSSARIIKSSRDCLEAAWSAASGLSVVQELADQAQYVTYVDDAQYLYYGPKETGRTFALVDGSIELEKALGEATNQIRVAYKNASNQPLYTAFAEHASERYALGIVRQRTIASETTDSTEAATLRSVALTDAAPTVRASLNVRAVRNEYNVREPLDLLSRGDVITIGDLSGAINKRSYTLAETSVNLMTGEVSVTPEAPIKQLDLWLAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A9AVY0</accession>
    <name>A9AVY0_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Haur_0570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0570"/>
    <dbReference type="EnsemblBacteria" id="ABX03218">
        <property type="protein sequence ID" value="ABX03218"/>
        <property type="gene ID" value="Haur_0570"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0570"/>
    <dbReference type="HOGENOM" id="CLU_1052794_0_0_0"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-579-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABX03218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="264" mass="29220" checksum="136CACB5B16B54F9" modified="2008-01-15" version="1">MLEQHNRQSIKSLIIFGSGLAYVLSIVMMEVLVGFALGDISESPLMQALVGIGILGTFISACLIPLALHYWLAPGTQFIVGILFWLVDVAVLAINATTSYQLIKKLELSSFFTMWQLAIPFIGPAITIIGWGLVYLADDGQKDRQSDRLLETSKRALMREAEYARVSAEHEFAMKQIAQVKQSLMMALQASDIAKVAEQGAYNSALQITRQIVGLPLNGSNHDQTESLHSQTHDHIEPQQELPFDTTPIIYTNNEGYADQPKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW19</accession>
    <name>A9AW19_HERA2</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zeta-phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Haur_0609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 3">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0609"/>
    <dbReference type="EnsemblBacteria" id="ABX03257">
        <property type="protein sequence ID" value="ABX03257"/>
        <property type="gene ID" value="Haur_0609"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0609"/>
    <dbReference type="eggNOG" id="COG1233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_0"/>
    <dbReference type="OMA" id="FTMRWVF"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-618-MON"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="4">
        <location>
            <begin position="11"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ABX03257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000787"/>
        </source>
    </evidence>
    <sequence length="495" mass="53769" checksum="D67ACFC2000CF413" modified="2008-01-15" version="1">MQHVVIVGGGLGGLAAALRLRAAGVAVTLFEKNTALGGKMAQVVQHGFRFDTGPSLFTMPWVVEELLASVGRDLASELTIKPVDPTCRYQWPDGTRLDAWSDLPKLLKEIERLEPADVAGFLGFMAFSAQIYQAAAEPFLLEPFQGLRTMLQPRLLRDVWKIAPLKTVDQAVRHYFKHPYLRQLFNRYATYNGSSPYRSPATFCIIPYVEIAQGGWYIDGGMYQLAATLGRIAGEMGVDIQLNSLVSEVIVTNKTATGVRLSDGRTINADYVIVNADAMYALDQLIPTTKAPTHELACSGFVLLLGVNRDYAQLQHHNIFFSGDYAAEFRAIFEHGVPAVDPTIYIAATCRSNPEHAPPGMLNLFVLVNAPVTGRVNWQREAAAYRDLVVRRLEQHGLVGLNQAIISETMLTPADLASMTNAQRGSLYGPASHGLQAAFLRPANQPAGLQNLALVGGATHPGGGIPLVLLSGKAGARWALQRLGVAEKPKLGTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-01-15" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A9AW26</accession>
    <name>A9AW26_HERA2</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanophycinase</fullName>
            <ecNumber evidence="4">3.4.15.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Haur_0616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)</name>
        <dbReference type="NCBI Taxonomy" id="316274"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Chloroflexia</taxon>
            <taxon>Herpetosiphonales</taxon>
            <taxon>Herpetosiphonaceae</taxon>
            <taxon>Herpetosiphon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2007-10" db="EMBL/GenBank/DDBJ databases">
            <title>Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute"/>
                <person name="Copeland A."/>
                <person name="Lucas S."/>
                <person name="Lapidus A."/>
                <person name="Barry K."/>
                <person name="Glavina del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Kiss H."/>
                <person name="Brettin T."/>
                <person name="Bruce D."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Schmutz J."/>
                <person name="Larimer F."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N."/>
                <person name="Kim E."/>
                <person name="Bryant D.A."/>
                <person name="Richardson P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="journal article" date="2011" name="Stand. Genomic Sci." volume="5" first="356" last="370">
            <title>Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).</title>
            <authorList>
                <person name="Kiss H."/>
                <person name="Nett M."/>
                <person name="Domin N."/>
                <person name="Martin K."/>
                <person name="Maresca J.A."/>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Lucas S."/>
                <person name="Berry K.W."/>
                <person name="Glavina Del Rio T."/>
                <person name="Dalin E."/>
                <person name="Tice H."/>
                <person name="Pitluck S."/>
                <person name="Richardson P."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Han C."/>
                <person name="Detter J.C."/>
                <person name="Schmutz J."/>
                <person name="Brettin T."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Kyrpides N.C."/>
                <person name="Ivanova N."/>
                <person name="Goker M."/>
                <person name="Woyke T."/>
                <person name="Klenk H.P."/>
                <person name="Bryant D.A."/>
            </authorList>
            <dbReference type="PubMed" id="22675585"/>
            <dbReference type="DOI" id="10.4056/sigs.2194987"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 23779 / DSM 785 / 114-95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + H2O = [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate</text>
            <dbReference type="Rhea" id="RHEA:12845"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13734"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137991"/>
            <dbReference type="EC" id="3.4.15.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.6" evidence="4"/>
    <dbReference type="EMBL" id="CP000875">
        <property type="protein sequence ID" value="ABX03264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="316274.Haur_0616"/>
    <dbReference type="EnsemblBacteria" id="ABX03264">
        <property type="protein sequence ID" value="ABX03264"/>
        <property type="gene ID" value="Haur_0616"/>
    </dbReference>
    <dbReference type="KEGG" id="hau:Haur_0616"/>
    <dbReference type="eggNOG" id="COG4242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053928_0_0_0"/>
    <dbReference type="OMA" id="FMTGGDQ"/>
    <dbReference type="BioCyc" id="HAUR316274:GHYA-625-MON"/>
    <dbReference type="Proteomes" id="UP000000787">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011811">
        <property type="entry name" value="Peptidase_S51_cyanophycinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032067">
        <property type="entry name" value="Cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02069">
        <property type="entry name" value="cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
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